Gene Symbol | FLI1 |
Entrez Gene ID | 2313 |
Full Name | Fli-1 proto-oncogene, ETS transcription factor |
Synonyms | BDPLT21,EWSR2,SIC-1 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]. |
Disorder MIM: | |
Disorder Html: | Bleeding disorder, platelet-type, 21, 617443 (3) |