POMZP3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	POMZP3
Entrez Gene ID	22932
Full Name	POM121 and ZP3 fusion
Synonyms	POM-ZP3,POM121
General protein information	Preferred Names POM121 and ZP3 fusion Names POM121 and ZP3 fusion protein POM (POM121 homolog, rat) and ZP3 fusion POM (POM121 rat homolog) and ZP3 fusion POM-ZP3 fusion protein POM121/ZP3 fusion protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q11.23
Summary	This gene appears to have resulted from a fusion of DNA sequences derived from 2 distinct loci, specifically through the duplication of two internal exons from the POM121 gene and four 3' exons from the ZP3 gene. The 5' end of this gene is similar to the 5` coding region of the POM121 gene which encodes an integral nuclear pore membrane protein. However, the protein encoded by this gene lacks the nuclear pore localization motif. The 3' end of this gene is similar to the last 4 exons of the zona pellucida glycoprotein 3 (ZP3) gene and the encoded protein retains one zona pellucida domain. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	600587

mRNA and Protein(s)

mRNA	Protein	Name
NM_152992.2	NP_694537.1	POM121 and ZP3 fusion protein isoform 2
NM_012230.3	NP_036362.3	POM121 and ZP3 fusion protein isoform 1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Creation of genome-wide protein expression libraries using random activation of gene expression.
Harrington JJ, Sherf B, Rundlett S, Jackson PD, Perry R, Cain S, Leventhal C, Thornton M, Ramachandran R, Whittington J, Lerner L, Costanzo D, McElligott K, Boozer S, Mays R, Smith E, Veloso N, Klika A, Hess J, Cothren K, Lo K, Offenbacher J, Danzig J, Ducar M
Nature biotechnology19(5)440-5(2001 May)

POM-ZP3, a bipartite transcript derived from human ZP3 and a POM121 homologue.
Kipersztok S, Osawa GA, Liang LF, Modi WS, Dean J
Genomics25(2)354-9(1995 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We observed functional nuclear pore complexes and intact nuclear envelopes in severely POM121-depleted cells.
Title: Nuclear pore complex assembly and maintenance in POM121- and gp210-deficient cells.

The following POMZP3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the POMZP3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu10226	NM_152992.2 Latest version!	Homo sapiens POM121 and ZP3 fusion (POMZP3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu11155	NM_012230.3 Latest version!	Homo sapiens POM121 and ZP3 fusion (POMZP3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

POMZP3 ( NM_152992.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_694537.1 Homo sapiens POM121 and ZP3 fusion (POMZP3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu10226
Clone ID Related Accession (Same CDS sequence)	NM_152992.2
Accession Version	NM_152992.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 348bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	POM121 and ZP3 fusion protein isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI084456.1, AC004980.5 and BG461659.1. On Aug 4, 2006 this sequence version replaced NM_152992.1. Transcript Variant: This variant (2) lacks two exons in the coding region which results in a frameshift and early stop codon, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: BC000487.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGTGTA GCCCAGTGAC TCTGAGGATC GCCCCTCCTG ACAGAAGATT TTCGCGTTCT 
GCGATACCAG AGCAGATAAT CAGCTCAACA CTGTCCTCAC CATCAAGTAA TGCCCCAGAC 
CCATGTGCAA AGGAGACTGT ACTGAGTGCC CTCAAAGAGA AGAAGAAGAA AAGGACAGTG 
GAGGAAGAAG ACCAAATATT CCTTGATGGC CAGGAAAATA AAAGAAGCTG TCTTGTCGAC 
GGTCTCACTG ATGCCTCTTC TGCATTCAAA GTTCCTCGAC CCGGGCCAGA TACACTCCAG 
TTCACAGTGG ATGTCTTCCA CTTTGCTAAT GACTCCAGAA ACATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_694537.1
CDS	748..1095
Translation	MVCSPVTLRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRSCLVDGLTDASSAFKVPRPGPDTLQFTVDVFHFANDSRNM

Target ORF information:

RefSeq Version	NM_152992.2
Organism	Homo sapiens(human)
Definition	Homo sapiens POM121 and ZP3 fusion (POMZP3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152992.2

ORF Insert Sequence:

ATGGTGTGTA GCCCAGTGAC TCTGAGGATC GCCCCTCCTG ACAGAAGATT TTCGCGTTCT 
GCGATACCAG AGCAGATAAT CAGCTCAACA CTGTCCTCAC CATCAAGTAA TGCCCCAGAC 
CCATGTGCAA AGGAGACTGT ACTGAGTGCC CTCAAAGAGA AGAAGAAGAA AAGGACAGTG 
GAGGAAGAAG ACCAAATATT CCTTGATGGC CAGGAAAATA AAAGAAGCTG TCTTGTCGAC 
GGTCTCACTG ATGCCTCTTC TGCATTCAAA GTTCCTCGAC CCGGGCCAGA TACACTCCAG 
TTCACAGTGG ATGTCTTCCA CTTTGCTAAT GACTCCAGAA ACATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

POMZP3 ( NM_012230.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_036362.3 Homo sapiens POM121 and ZP3 fusion (POMZP3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu11155
Clone ID Related Accession (Same CDS sequence)	NM_012230.3
Accession Version	NM_012230.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 564bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	POM121 and ZP3 fusion protein isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI084456.1, AC004980.5 and BG461659.1. On Aug 4, 2006 this sequence version replaced NM_012230.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR1163658.300188.1, SRR1163658.17052.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTGTGTA GCCCAGTGAC TCTGAGGATC GCCCCTCCTG ACAGAAGATT TTCGCGTTCT 
GCGATACCAG AGCAGATAAT CAGCTCAACA CTGTCCTCAC CATCAAGTAA TGCCCCAGAC 
CCATGTGCAA AGGAGACTGT ACTGAGTGCC CTCAAAGAGA AGAAGAAGAA AAGGACAGTG 
GAGGAAGAAG ACCAAATATT CCTTGATGGC CAGGAAAATA AAAGAAGCTG TCTTGTCGAC 
GGTCTCACTG ATGCCTCTTC TGCATTCAAA GTTCCTCGAC CCGGGCCAGA TACACTCCAG 
TTCACAGTGG ATGTCTTCCA CTTTGCTAAT GACTCCAGAA ACATGATATA CATCACCTGC 
CACCTGAAGG TCACCCTAGC TGAGCAGGAC CCAGATGAAC TCAACAAGGC CTGTTCCTTC 
AGCAAGCCTT CCAACAGCTG GTTCCCAGTG GAAGGCCTGG CTGACATCTG TCAATGCTGT 
AACAAAGGTG ACTGTGGCAC TCCAAGCCAT TCCAGGAGGC AGCCTCGTGT CGTGAGCCAG 
TGGTCCACGT CTGCTTCCCT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036362.3
CDS	748..1311
Translation	MVCSPVTLRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRSCLVDGLTDASSAFKVPRPGPDTLQFTVDVFHFANDSRNMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGLADICQCCNKGDCGTPSHSRRQPRVVSQWSTSASL

Target ORF information:

RefSeq Version	NM_012230.3
Organism	Homo sapiens(human)
Definition	Homo sapiens POM121 and ZP3 fusion (POMZP3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012230.3

ORF Insert Sequence:

ATGGTGTGTA GCCCAGTGAC TCTGAGGATC GCCCCTCCTG ACAGAAGATT TTCGCGTTCT 
GCGATACCAG AGCAGATAAT CAGCTCAACA CTGTCCTCAC CATCAAGTAA TGCCCCAGAC 
CCATGTGCAA AGGAGACTGT ACTGAGTGCC CTCAAAGAGA AGAAGAAGAA AAGGACAGTG 
GAGGAAGAAG ACCAAATATT CCTTGATGGC CAGGAAAATA AAAGAAGCTG TCTTGTCGAC 
GGTCTCACTG ATGCCTCTTC TGCATTCAAA GTTCCTCGAC CCGGGCCAGA TACACTCCAG 
TTCACAGTGG ATGTCTTCCA CTTTGCTAAT GACTCCAGAA ACATGATATA CATCACCTGC 
CACCTGAAGG TCACCCTAGC TGAGCAGGAC CCAGATGAAC TCAACAAGGC CTGTTCCTTC 
AGCAAGCCTT CCAACAGCTG GTTCCCAGTG GAAGGCCTGG CTGACATCTG TCAATGCTGT 
AACAAAGGTG ACTGTGGCAC TCCAAGCCAT TCCAGGAGGC AGCCTCGTGT CGTGAGCCAG 
TGGTCCACGT CTGCTTCCCT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Creation of genome-wide protein expression libraries using random activation of gene expression.
Nature biotechnology19(5)440-5(2001 May)
Harrington JJ,Sherf B,Rundlett S,Jackson PD,Perry R,Cain S,Leventhal C,Thornton M,Ramachandran R,Whittington J,Lerner L,Costanzo D,McElligott K,Boozer S,Mays R,Smith E,Veloso N,Klika A,Hess J,Cothren K,Lo K,Offenbacher J,Danzig J,Ducar M

POM-ZP3, a bipartite transcript derived from human ZP3 and a POM121 homologue.
Genomics25(2)354-9(1995 Jan)
Kipersztok S,Osawa GA,Liang LF,Modi WS,Dean J

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POMZP3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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