NLRP1 gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
NM_033006.3	NP_127499.1	NACHT, LRR and PYD domains-containing protein 1 isoform 3
NM_001033053.2	NP_001028225.1	NACHT, LRR and PYD domains-containing protein 1 isoform 5
NM_033007.4	NP_127500.1	NACHT, LRR and PYD domains-containing protein 1 isoform 4
NM_001033053.3	NP_001028225.1	NACHT, LRR and PYD domains-containing protein 1 isoform 5
NM_033006.4	NP_127499.1	NACHT, LRR and PYD domains-containing protein 1 isoform 3
NM_033007.3	NP_127500.1	NACHT, LRR and PYD domains-containing protein 1 isoform 4
NM_033004.3	NP_127497.1	NACHT, LRR and PYD domains-containing protein 1 isoform 1
NM_014922.5	NP_055737.1	NACHT, LRR and PYD domains-containing protein 1 isoform 2
NM_014922.4	NP_055737.1	NACHT, LRR and PYD domains-containing protein 1 isoform 2
NM_033004.4	NP_127497.1	NACHT, LRR and PYD domains-containing protein 1 isoform 1

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25361	NM_033004.4 Latest version!	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$519.50-$727.30 $1039.00
OHu25606	NM_001033053.3 Latest version!	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
OHu25373	NM_014922.5 Latest version!	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$923.30 $1319.00
OHu25556	NM_033007.4 Latest version!	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$923.30 $1319.00
OHu25557	NM_033006.4 Latest version!	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$923.30 $1319.00
View Old Accession Versions >>
OHu25606	NM_001033053.2	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
OHu25557	NM_033006.3	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$923.30 $1319.00
OHu25556	NM_033007.3	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$923.30 $1319.00
OHu25373	NM_014922.4	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$923.30 $1319.00
OHu25361	NM_033004.3	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$519.50-$727.30 $1039.00
Hide Old Accession Versions >>

NLRP1 ( NM_033004.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_127497.1 Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu25361
Clone ID Related Accession (Same CDS sequence)	NM_033004.3 , NM_033004.4
Accession Version	NM_033004.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4422bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055839.9, AF229060.1, AB023143.1 and AI819334.1. On Dec 14, 2006 this sequence version replaced NM_033004.2. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF229060.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GCTGGACCAG 
ACAACTCTGA GTGATGAGAT GAGGCAGGAA CTGAGGGCCC TGGAGCAGGA GAAACCTCAG 
CTGCTCATCT TCAGCAGACG GAAACCAAGT GTGATGACCC CTACTGAGGG CCTGGATACG 
GGAGAGATGA GTAATAGCAC ATCCTCACTC AAGCGGCAGA GACTCGGATC AGAGAGGGCG 
GCTTCCCATG TTGCTCAGGC TAATCTCAAA CTCCTGGACG TGAGCAAGAT CTTCCCAATT 
GCTGAGATTG CAGAGGAAAG CTCCCCAGAG GTAGTACCGG TGGAACTCTT GTGCGTGCCT 
TCTCCTGCCT CTCAAGGGGA CCTGCATACG AAGCCTTTGG GGACTGACGA TGACTTCTGG 
GGCCCCACGG GGCCTGTGGC TACTGAGGTA GTTGACAAAG AAAAGAACTT GTACCGAGTT 
CACTTCCCTG TAGCTGGCTC CTACCGCTGG CCCAACACGG GTCTCTGCTT TGTGATGAGA 
GAAGCGGTGA CCGTTGAGAT TGAATTCTGT GTGTGGGACC AGTTCCTGGG TGAGATCAAC 
CCACAGCACA GCTGGATGGT GGCAGGGCCT CTGCTGGACA TCAAGGCTGA GCCTGGAGCT 
GTGGAAGCTG TGCACCTCCC TCACTTTGTG GCTCTCCAAG GGGGCCATGT GGACACATCC 
CTGTTCCAAA TGGCCCACTT TAAAGAGGAG GGGATGCTCC TGGAGAAGCC AGCCAGGGTG 
GAGCTGCATC ACATAGTTCT GGAAAACCCC AGCTTCTCCC CCTTGGGAGT CCTCCTGAAA 
ATGATCCATA ATGCCCTGCG CTTCATTCCC GTCACCTCTG TGGTGTTGCT TTACCACCGC 
GTCCATCCTG AGGAAGTCAC CTTCCACCTC TACCTGATCC CAAGTGACTG CTCCATTCGG 
AAGGCCATAG ATGATCTAGA AATGAAATTC CAGTTTGTGC GAATCCACAA GCCACCCCCG 
CTGACCCCAC TTTATATGGG CTGTCGTTAC ACTGTGTCTG GGTCTGGTTC AGGGATGCTG 
GAAATACTCC CCAAGGAACT GGAGCTCTGC TATCGAAGCC CTGGAGAAGA CCAGCTGTTC 
TCGGAGTTCT ACGTTGGCCA CTTGGGATCA GGGATCAGGC TGCAAGTGAA AGACAAGAAA 
GATGAGACTC TGGTGTGGGA GGCCTTGGTG AAACCAGGAG ATCTCATGCC TGCAACTACT 
CTGATCCCTC CAGCCCGCAT AGCCGTACCT TCACCTCTGG ATGCCCCGCA GTTGCTGCAC 
TTTGTGGACC AGTATCGAGA GCAGCTGATA GCCCGAGTGA CATCGGTGGA GGTTGTCTTG 
GACAAACTGC ATGGACAGGT GCTGAGCCAG GAGCAGTACG AGAGGGTGCT GGCTGAGAAC 
ACGAGGCCCA GCCAGATGCG GAAGCTGTTC AGCTTGAGCC AGTCCTGGGA CCGGAAGTGC 
AAAGATGGAC TCTACCAAGC CCTGAAGGAG ACCCATCCTC ACCTCATTAT GGAACTCTGG 
GAGAAGGGCA GCAAAAAGGG ACTCCTGCCA CTCAGCAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_127497.1
CDS	556..4977
Translation	MAGGAWGRLACYLEFLKKEELKEFQLLLANKAHSRSSSGETPAQPEKTSGMEVASYLVAQYGEQRAWDLALHTWEQMGLRSLCAQAQEGAGHSPSFPYSPSEPHLGSPSQPTSTAVLMPWIHELPAGCTQGSERRVLRQLPDTSGRRWREISASLLYQALPSSPDHESPSQESPNAPTSTAVLGSWGSPPQPSLAPREQEAPGTQWPLDETSGIYYTEIREREREKSEKGRPPWAAVVGTPPQAHTSLQPHHHPWEPSVRESLCSTWPWKNEDFNQKFTQLLLLQRPHPRSQDPLVKRSWPDYVEENRGHLIEIRDLFGPGLDTQEPRIVILQGAAGIGKSTLARQVKEAWGRGQLYGDRFQHVFYFSCRELAQSKVVSLAELIGKDGTATPAPIRQILSRPERLLFILDGVDEPGWVLQEPSSELCLHWSQPQPADALLGSLLGKTILPEASFLITARTTALQNLIPSLEQARWVEVLGFSESSRKEYFYRYFTDERQAIRAFRLVKSNKELWALCLVPWVSWLACTCLMQQMKRKEKLTLTSKTTTTLCLHYLAQALQAQPLGPQLRDLCSLAAEGIWQKKTLFSPDDLRKHGLDGAIISTFLKMGILQEHPIPLSYSFIHLCFQEFFAAMSYVLEDEKGRGKHSNCIIDLEKTLEAYGIHGLFGASTTRFLLGLLSDEGEREMENIFHCRLSQGRNLMQWVPSLQLLLQPHSLESLHCLYETRNKTFLTQVMAHFEEMGMCVETDMELLVCTFCIKFSRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAYWQILFSVLKVTRNLKELDLSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSFNVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVLSASPSLKELDLQQNNLDDVGVRLLCEGLRHPACKLIRLGLDQTTLSDEMRQELRALEQEKPQLLIFSRRKPSVMTPTEGLDTGEMSNSTSSLKRQRLGSERAASHVAQANLKLLDVSKIFPIAEIAEESSPEVVPVELLCVPSPASQGDLHTKPLGTDDDFWGPTGPVATEVVDKEKNLYRVHFPVAGSYRWPNTGLCFVMREAVTVEIEFCVWDQFLGEINPQHSWMVAGPLLDIKAEPGAVEAVHLPHFVALQGGHVDTSLFQMAHFKEEGMLLEKPARVELHHIVLENPSFSPLGVLLKMIHNALRFIPVTSVVLLYHRVHPEEVTFHLYLIPSDCSIRKAIDDLEMKFQFVRIHKPPPLTPLYMGCRYTVSGSGSGMLEILPKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVWEALVKPGDLMPATTLIPPARIAVPSPLDAPQLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQYERVLAENTRPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMELWEKGSKKGLLPLSS

Target ORF information:

RefSeq Version	NM_033004.3
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033004.3

ORF Insert Sequence:

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GCTGGACCAG 
ACAACTCTGA GTGATGAGAT GAGGCAGGAA CTGAGGGCCC TGGAGCAGGA GAAACCTCAG 
CTGCTCATCT TCAGCAGACG GAAACCAAGT GTGATGACCC CTACTGAGGG CCTGGATACG 
GGAGAGATGA GTAATAGCAC ATCCTCACTC AAGCGGCAGA GACTCGGATC AGAGAGGGCG 
GCTTCCCATG TTGCTCAGGC TAATCTCAAA CTCCTGGACG TGAGCAAGAT CTTCCCAATT 
GCTGAGATTG CAGAGGAAAG CTCCCCAGAG GTAGTACCGG TGGAACTCTT GTGCGTGCCT 
TCTCCTGCCT CTCAAGGGGA CCTGCATACG AAGCCTTTGG GGACTGACGA TGACTTCTGG 
GGCCCCACGG GGCCTGTGGC TACTGAGGTA GTTGACAAAG AAAAGAACTT GTACCGAGTT 
CACTTCCCTG TAGCTGGCTC CTACCGCTGG CCCAACACGG GTCTCTGCTT TGTGATGAGA 
GAAGCGGTGA CCGTTGAGAT TGAATTCTGT GTGTGGGACC AGTTCCTGGG TGAGATCAAC 
CCACAGCACA GCTGGATGGT GGCAGGGCCT CTGCTGGACA TCAAGGCTGA GCCTGGAGCT 
GTGGAAGCTG TGCACCTCCC TCACTTTGTG GCTCTCCAAG GGGGCCATGT GGACACATCC 
CTGTTCCAAA TGGCCCACTT TAAAGAGGAG GGGATGCTCC TGGAGAAGCC AGCCAGGGTG 
GAGCTGCATC ACATAGTTCT GGAAAACCCC AGCTTCTCCC CCTTGGGAGT CCTCCTGAAA 
ATGATCCATA ATGCCCTGCG CTTCATTCCC GTCACCTCTG TGGTGTTGCT TTACCACCGC 
GTCCATCCTG AGGAAGTCAC CTTCCACCTC TACCTGATCC CAAGTGACTG CTCCATTCGG 
AAGGCCATAG ATGATCTAGA AATGAAATTC CAGTTTGTGC GAATCCACAA GCCACCCCCG 
CTGACCCCAC TTTATATGGG CTGTCGTTAC ACTGTGTCTG GGTCTGGTTC AGGGATGCTG 
GAAATACTCC CCAAGGAACT GGAGCTCTGC TATCGAAGCC CTGGAGAAGA CCAGCTGTTC 
TCGGAGTTCT ACGTTGGCCA CTTGGGATCA GGGATCAGGC TGCAAGTGAA AGACAAGAAA 
GATGAGACTC TGGTGTGGGA GGCCTTGGTG AAACCAGGAG ATCTCATGCC TGCAACTACT 
CTGATCCCTC CAGCCCGCAT AGCCGTACCT TCACCTCTGG ATGCCCCGCA GTTGCTGCAC 
TTTGTGGACC AGTATCGAGA GCAGCTGATA GCCCGAGTGA CATCGGTGGA GGTTGTCTTG 
GACAAACTGC ATGGACAGGT GCTGAGCCAG GAGCAGTACG AGAGGGTGCT GGCTGAGAAC 
ACGAGGCCCA GCCAGATGCG GAAGCTGTTC AGCTTGAGCC AGTCCTGGGA CCGGAAGTGC 
AAAGATGGAC TCTACCAAGC CCTGAAGGAG ACCCATCCTC ACCTCATTAT GGAACTCTGG 
GAGAAGGGCA GCAAAAAGGG ACTCCTGCCA CTCAGCAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP1 ( NM_033004.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_127497.1 Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu25361
Clone ID Related Accession (Same CDS sequence)	NM_033004.3 , NM_033004.4
Accession Version	NM_033004.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4422bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-10
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055839.9, AF229060.1, AB023143.1 and AI819334.1. On Nov 22, 2018 this sequence version replaced NM_033004.3. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF229060.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000572272.6/ ENSP00000460475.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GCTGGACCAG 
ACAACTCTGA GTGATGAGAT GAGGCAGGAA CTGAGGGCCC TGGAGCAGGA GAAACCTCAG 
CTGCTCATCT TCAGCAGACG GAAACCAAGT GTGATGACCC CTACTGAGGG CCTGGATACG 
GGAGAGATGA GTAATAGCAC ATCCTCACTC AAGCGGCAGA GACTCGGATC AGAGAGGGCG 
GCTTCCCATG TTGCTCAGGC TAATCTCAAA CTCCTGGACG TGAGCAAGAT CTTCCCAATT 
GCTGAGATTG CAGAGGAAAG CTCCCCAGAG GTAGTACCGG TGGAACTCTT GTGCGTGCCT 
TCTCCTGCCT CTCAAGGGGA CCTGCATACG AAGCCTTTGG GGACTGACGA TGACTTCTGG 
GGCCCCACGG GGCCTGTGGC TACTGAGGTA GTTGACAAAG AAAAGAACTT GTACCGAGTT 
CACTTCCCTG TAGCTGGCTC CTACCGCTGG CCCAACACGG GTCTCTGCTT TGTGATGAGA 
GAAGCGGTGA CCGTTGAGAT TGAATTCTGT GTGTGGGACC AGTTCCTGGG TGAGATCAAC 
CCACAGCACA GCTGGATGGT GGCAGGGCCT CTGCTGGACA TCAAGGCTGA GCCTGGAGCT 
GTGGAAGCTG TGCACCTCCC TCACTTTGTG GCTCTCCAAG GGGGCCATGT GGACACATCC 
CTGTTCCAAA TGGCCCACTT TAAAGAGGAG GGGATGCTCC TGGAGAAGCC AGCCAGGGTG 
GAGCTGCATC ACATAGTTCT GGAAAACCCC AGCTTCTCCC CCTTGGGAGT CCTCCTGAAA 
ATGATCCATA ATGCCCTGCG CTTCATTCCC GTCACCTCTG TGGTGTTGCT TTACCACCGC 
GTCCATCCTG AGGAAGTCAC CTTCCACCTC TACCTGATCC CAAGTGACTG CTCCATTCGG 
AAGGCCATAG ATGATCTAGA AATGAAATTC CAGTTTGTGC GAATCCACAA GCCACCCCCG 
CTGACCCCAC TTTATATGGG CTGTCGTTAC ACTGTGTCTG GGTCTGGTTC AGGGATGCTG 
GAAATACTCC CCAAGGAACT GGAGCTCTGC TATCGAAGCC CTGGAGAAGA CCAGCTGTTC 
TCGGAGTTCT ACGTTGGCCA CTTGGGATCA GGGATCAGGC TGCAAGTGAA AGACAAGAAA 
GATGAGACTC TGGTGTGGGA GGCCTTGGTG AAACCAGGAG ATCTCATGCC TGCAACTACT 
CTGATCCCTC CAGCCCGCAT AGCCGTACCT TCACCTCTGG ATGCCCCGCA GTTGCTGCAC 
TTTGTGGACC AGTATCGAGA GCAGCTGATA GCCCGAGTGA CATCGGTGGA GGTTGTCTTG 
GACAAACTGC ATGGACAGGT GCTGAGCCAG GAGCAGTACG AGAGGGTGCT GGCTGAGAAC 
ACGAGGCCCA GCCAGATGCG GAAGCTGTTC AGCTTGAGCC AGTCCTGGGA CCGGAAGTGC 
AAAGATGGAC TCTACCAAGC CCTGAAGGAG ACCCATCCTC ACCTCATTAT GGAACTCTGG 
GAGAAGGGCA GCAAAAAGGG ACTCCTGCCA CTCAGCAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_127497.1
CDS	553..4974
Translation	MAGGAWGRLACYLEFLKKEELKEFQLLLANKAHSRSSSGETPAQPEKTSGMEVASYLVAQYGEQRAWDLALHTWEQMGLRSLCAQAQEGAGHSPSFPYSPSEPHLGSPSQPTSTAVLMPWIHELPAGCTQGSERRVLRQLPDTSGRRWREISASLLYQALPSSPDHESPSQESPNAPTSTAVLGSWGSPPQPSLAPREQEAPGTQWPLDETSGIYYTEIREREREKSEKGRPPWAAVVGTPPQAHTSLQPHHHPWEPSVRESLCSTWPWKNEDFNQKFTQLLLLQRPHPRSQDPLVKRSWPDYVEENRGHLIEIRDLFGPGLDTQEPRIVILQGAAGIGKSTLARQVKEAWGRGQLYGDRFQHVFYFSCRELAQSKVVSLAELIGKDGTATPAPIRQILSRPERLLFILDGVDEPGWVLQEPSSELCLHWSQPQPADALLGSLLGKTILPEASFLITARTTALQNLIPSLEQARWVEVLGFSESSRKEYFYRYFTDERQAIRAFRLVKSNKELWALCLVPWVSWLACTCLMQQMKRKEKLTLTSKTTTTLCLHYLAQALQAQPLGPQLRDLCSLAAEGIWQKKTLFSPDDLRKHGLDGAIISTFLKMGILQEHPIPLSYSFIHLCFQEFFAAMSYVLEDEKGRGKHSNCIIDLEKTLEAYGIHGLFGASTTRFLLGLLSDEGEREMENIFHCRLSQGRNLMQWVPSLQLLLQPHSLESLHCLYETRNKTFLTQVMAHFEEMGMCVETDMELLVCTFCIKFSRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAYWQILFSVLKVTRNLKELDLSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSFNVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVLSASPSLKELDLQQNNLDDVGVRLLCEGLRHPACKLIRLGLDQTTLSDEMRQELRALEQEKPQLLIFSRRKPSVMTPTEGLDTGEMSNSTSSLKRQRLGSERAASHVAQANLKLLDVSKIFPIAEIAEESSPEVVPVELLCVPSPASQGDLHTKPLGTDDDFWGPTGPVATEVVDKEKNLYRVHFPVAGSYRWPNTGLCFVMREAVTVEIEFCVWDQFLGEINPQHSWMVAGPLLDIKAEPGAVEAVHLPHFVALQGGHVDTSLFQMAHFKEEGMLLEKPARVELHHIVLENPSFSPLGVLLKMIHNALRFIPVTSVVLLYHRVHPEEVTFHLYLIPSDCSIRKAIDDLEMKFQFVRIHKPPPLTPLYMGCRYTVSGSGSGMLEILPKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVWEALVKPGDLMPATTLIPPARIAVPSPLDAPQLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQYERVLAENTRPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMELWEKGSKKGLLPLSS

Target ORF information:

RefSeq Version	NM_033004.4
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033004.4

ORF Insert Sequence:

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GCTGGACCAG 
ACAACTCTGA GTGATGAGAT GAGGCAGGAA CTGAGGGCCC TGGAGCAGGA GAAACCTCAG 
CTGCTCATCT TCAGCAGACG GAAACCAAGT GTGATGACCC CTACTGAGGG CCTGGATACG 
GGAGAGATGA GTAATAGCAC ATCCTCACTC AAGCGGCAGA GACTCGGATC AGAGAGGGCG 
GCTTCCCATG TTGCTCAGGC TAATCTCAAA CTCCTGGACG TGAGCAAGAT CTTCCCAATT 
GCTGAGATTG CAGAGGAAAG CTCCCCAGAG GTAGTACCGG TGGAACTCTT GTGCGTGCCT 
TCTCCTGCCT CTCAAGGGGA CCTGCATACG AAGCCTTTGG GGACTGACGA TGACTTCTGG 
GGCCCCACGG GGCCTGTGGC TACTGAGGTA GTTGACAAAG AAAAGAACTT GTACCGAGTT 
CACTTCCCTG TAGCTGGCTC CTACCGCTGG CCCAACACGG GTCTCTGCTT TGTGATGAGA 
GAAGCGGTGA CCGTTGAGAT TGAATTCTGT GTGTGGGACC AGTTCCTGGG TGAGATCAAC 
CCACAGCACA GCTGGATGGT GGCAGGGCCT CTGCTGGACA TCAAGGCTGA GCCTGGAGCT 
GTGGAAGCTG TGCACCTCCC TCACTTTGTG GCTCTCCAAG GGGGCCATGT GGACACATCC 
CTGTTCCAAA TGGCCCACTT TAAAGAGGAG GGGATGCTCC TGGAGAAGCC AGCCAGGGTG 
GAGCTGCATC ACATAGTTCT GGAAAACCCC AGCTTCTCCC CCTTGGGAGT CCTCCTGAAA 
ATGATCCATA ATGCCCTGCG CTTCATTCCC GTCACCTCTG TGGTGTTGCT TTACCACCGC 
GTCCATCCTG AGGAAGTCAC CTTCCACCTC TACCTGATCC CAAGTGACTG CTCCATTCGG 
AAGGCCATAG ATGATCTAGA AATGAAATTC CAGTTTGTGC GAATCCACAA GCCACCCCCG 
CTGACCCCAC TTTATATGGG CTGTCGTTAC ACTGTGTCTG GGTCTGGTTC AGGGATGCTG 
GAAATACTCC CCAAGGAACT GGAGCTCTGC TATCGAAGCC CTGGAGAAGA CCAGCTGTTC 
TCGGAGTTCT ACGTTGGCCA CTTGGGATCA GGGATCAGGC TGCAAGTGAA AGACAAGAAA 
GATGAGACTC TGGTGTGGGA GGCCTTGGTG AAACCAGGAG ATCTCATGCC TGCAACTACT 
CTGATCCCTC CAGCCCGCAT AGCCGTACCT TCACCTCTGG ATGCCCCGCA GTTGCTGCAC 
TTTGTGGACC AGTATCGAGA GCAGCTGATA GCCCGAGTGA CATCGGTGGA GGTTGTCTTG 
GACAAACTGC ATGGACAGGT GCTGAGCCAG GAGCAGTACG AGAGGGTGCT GGCTGAGAAC 
ACGAGGCCCA GCCAGATGCG GAAGCTGTTC AGCTTGAGCC AGTCCTGGGA CCGGAAGTGC 
AAAGATGGAC TCTACCAAGC CCTGAAGGAG ACCCATCCTC ACCTCATTAT GGAACTCTGG 
GAGAAGGGCA GCAAAAAGGG ACTCCTGCCA CTCAGCAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP1 ( NM_001033053.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001028225.1 Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 5, mRNA.

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CloneID	OHu25606
Clone ID Related Accession (Same CDS sequence)	NM_001033053.2 , NM_001033053.3
Accession Version	NM_001033053.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4128bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 1 isoform 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055839.9, AB023143.1, AK026398.1 and BP391071.1. This sequence is a reference standard in the RefSeqGene project. On or before Nov 1, 2008 this sequence version replaced XR_041053.1, NM_001033053.1. Transcript Variant: This variant (5) has an alternate 3' sequence, as compared to variant 1. The resulting isoform (5) has a distinct and shorter C-terminus, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BC051787.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GCTGGACCAG 
ACAACTCTGA GTGATGAGAT GAGGCAGGAA CTGAGGGCCC TGGAGCAGGA GAAACCTCAG 
CTGCTCATCT TCAGCAGACG GAAACCAAGT GTGATGACCC CTACTGAGGG CCTGGATACG 
GGAGAGATGA GTAATAGCAC ATCCTCACTC AAGCGGCAGA GACTCGGATC AGAGAGGGCG 
GCTTCCCATG TTGCTCAGGC TAATCTCAAA CTCCTGGACG TGAGCAAGAT CTTCCCAATT 
GCTGAGATTG CAGGCAAGAG CCACGAGGAA AGCTCCCCAG AGGTAGTACC GGTGGAACTC 
TTGTGCGTGC CTTCTCCTGC CTCTCAAGGG GACCTGCATA CGAAGCCTTT GGGGACTGAC 
GATGACTTCT GGGGCCCCAC GGGGCCTGTG GCTACTGAGG TAGTTGACAA AGAAAAGAAC 
TTGTACCGAG TTCACTTCCC TGTAGCTGGC TCCTACCGCT GGCCCAACAC GGGTCTCTGC 
TTTGTGATGA GAGAAGCGGT GACCGTTGAG ATTGAATTCT GTGTGTGGGA CCAGTTCCTG 
GGTGAGATCA ACCCACAGCA CAGCTGGATG GTGGCAGGGC CTCTGCTGGA CATCAAGGCT 
GAGCCTGGAG CTGTGGAAGC TGTGCACCTC CCTCACTTTG TGGCTCTCCA AGGGGGCCAT 
GTGGACACAT CCCTGTTCCA AATGGCCCAC TTTAAAGAGG AGGGGATGCT CCTGGAGAAG 
CCAGCCAGGG TGGAGCTGCA TCACATAGTT CTGGAAAACC CCAGCTTCTC CCCCTTGGGA 
GTCCTCCTGA AAATGATCCA TAATGCCCTG CGCTTCATTC CCGTCACCTC TGTGGTGTTG 
CTTTACCACC GCGTCCATCC TGAGGAAGTC ACCTTCCACC TCTACCTGAT CCCAAGTGAC 
TGCTCCATTC GGAAGGCCAT AGATGATCTA GAAATGAAAT TCCAGTTTGT GCGAATCCAC 
AAGCCACCCC CGCTGACCCC ACTTTATATG GGCTGTCGTT ACACTGTGTC TGGGTCTGGT 
TCAGGGATGC TGGAAATACT CCCCAAGGAA CTGGAGCTCT GCTATCGAAG CCCTGGAGAA 
GACCAGCTGT TCTCGGAGTT CTACGTTGGC CACTTGGGAT CAGGGATCAG GCTGCAAGTG 
AAAGACAAGA AAGATGAGAC TCTGGTGTGG GAGGCCTTGG TGAAACCAGG AAGGAACACC 
AGCCAGCCGT GGAACCTCAG GTGCAACAGA GACGCCAGGA GATACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001028225.1
CDS	556..4683
Translation	MAGGAWGRLACYLEFLKKEELKEFQLLLANKAHSRSSSGETPAQPEKTSGMEVASYLVAQYGEQRAWDLALHTWEQMGLRSLCAQAQEGAGHSPSFPYSPSEPHLGSPSQPTSTAVLMPWIHELPAGCTQGSERRVLRQLPDTSGRRWREISASLLYQALPSSPDHESPSQESPNAPTSTAVLGSWGSPPQPSLAPREQEAPGTQWPLDETSGIYYTEIREREREKSEKGRPPWAAVVGTPPQAHTSLQPHHHPWEPSVRESLCSTWPWKNEDFNQKFTQLLLLQRPHPRSQDPLVKRSWPDYVEENRGHLIEIRDLFGPGLDTQEPRIVILQGAAGIGKSTLARQVKEAWGRGQLYGDRFQHVFYFSCRELAQSKVVSLAELIGKDGTATPAPIRQILSRPERLLFILDGVDEPGWVLQEPSSELCLHWSQPQPADALLGSLLGKTILPEASFLITARTTALQNLIPSLEQARWVEVLGFSESSRKEYFYRYFTDERQAIRAFRLVKSNKELWALCLVPWVSWLACTCLMQQMKRKEKLTLTSKTTTTLCLHYLAQALQAQPLGPQLRDLCSLAAEGIWQKKTLFSPDDLRKHGLDGAIISTFLKMGILQEHPIPLSYSFIHLCFQEFFAAMSYVLEDEKGRGKHSNCIIDLEKTLEAYGIHGLFGASTTRFLLGLLSDEGEREMENIFHCRLSQGRNLMQWVPSLQLLLQPHSLESLHCLYETRNKTFLTQVMAHFEEMGMCVETDMELLVCTFCIKFSRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAYWQILFSVLKVTRNLKELDLSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSFNVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVLSASPSLKELDLQQNNLDDVGVRLLCEGLRHPACKLIRLGLDQTTLSDEMRQELRALEQEKPQLLIFSRRKPSVMTPTEGLDTGEMSNSTSSLKRQRLGSERAASHVAQANLKLLDVSKIFPIAEIAGKSHEESSPEVVPVELLCVPSPASQGDLHTKPLGTDDDFWGPTGPVATEVVDKEKNLYRVHFPVAGSYRWPNTGLCFVMREAVTVEIEFCVWDQFLGEINPQHSWMVAGPLLDIKAEPGAVEAVHLPHFVALQGGHVDTSLFQMAHFKEEGMLLEKPARVELHHIVLENPSFSPLGVLLKMIHNALRFIPVTSVVLLYHRVHPEEVTFHLYLIPSDCSIRKAIDDLEMKFQFVRIHKPPPLTPLYMGCRYTVSGSGSGMLEILPKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVWEALVKPGRNTSQPWNLRCNRDARRY

Target ORF information:

RefSeq Version	NM_001033053.2
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001033053.2

ORF Insert Sequence:

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GCTGGACCAG 
ACAACTCTGA GTGATGAGAT GAGGCAGGAA CTGAGGGCCC TGGAGCAGGA GAAACCTCAG 
CTGCTCATCT TCAGCAGACG GAAACCAAGT GTGATGACCC CTACTGAGGG CCTGGATACG 
GGAGAGATGA GTAATAGCAC ATCCTCACTC AAGCGGCAGA GACTCGGATC AGAGAGGGCG 
GCTTCCCATG TTGCTCAGGC TAATCTCAAA CTCCTGGACG TGAGCAAGAT CTTCCCAATT 
GCTGAGATTG CAGGCAAGAG CCACGAGGAA AGCTCCCCAG AGGTAGTACC GGTGGAACTC 
TTGTGCGTGC CTTCTCCTGC CTCTCAAGGG GACCTGCATA CGAAGCCTTT GGGGACTGAC 
GATGACTTCT GGGGCCCCAC GGGGCCTGTG GCTACTGAGG TAGTTGACAA AGAAAAGAAC 
TTGTACCGAG TTCACTTCCC TGTAGCTGGC TCCTACCGCT GGCCCAACAC GGGTCTCTGC 
TTTGTGATGA GAGAAGCGGT GACCGTTGAG ATTGAATTCT GTGTGTGGGA CCAGTTCCTG 
GGTGAGATCA ACCCACAGCA CAGCTGGATG GTGGCAGGGC CTCTGCTGGA CATCAAGGCT 
GAGCCTGGAG CTGTGGAAGC TGTGCACCTC CCTCACTTTG TGGCTCTCCA AGGGGGCCAT 
GTGGACACAT CCCTGTTCCA AATGGCCCAC TTTAAAGAGG AGGGGATGCT CCTGGAGAAG 
CCAGCCAGGG TGGAGCTGCA TCACATAGTT CTGGAAAACC CCAGCTTCTC CCCCTTGGGA 
GTCCTCCTGA AAATGATCCA TAATGCCCTG CGCTTCATTC CCGTCACCTC TGTGGTGTTG 
CTTTACCACC GCGTCCATCC TGAGGAAGTC ACCTTCCACC TCTACCTGAT CCCAAGTGAC 
TGCTCCATTC GGAAGGCCAT AGATGATCTA GAAATGAAAT TCCAGTTTGT GCGAATCCAC 
AAGCCACCCC CGCTGACCCC ACTTTATATG GGCTGTCGTT ACACTGTGTC TGGGTCTGGT 
TCAGGGATGC TGGAAATACT CCCCAAGGAA CTGGAGCTCT GCTATCGAAG CCCTGGAGAA 
GACCAGCTGT TCTCGGAGTT CTACGTTGGC CACTTGGGAT CAGGGATCAG GCTGCAAGTG 
AAAGACAAGA AAGATGAGAC TCTGGTGTGG GAGGCCTTGG TGAAACCAGG AAGGAACACC 
AGCCAGCCGT GGAACCTCAG GTGCAACAGA GACGCCAGGA GATACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP1 ( NM_001033053.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001028225.1 Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 5, mRNA.

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CloneID	OHu25606
Clone ID Related Accession (Same CDS sequence)	NM_001033053.2 , NM_001033053.3
Accession Version	NM_001033053.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4128bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-10
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 1 isoform 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055839.9, AB023143.1, AK026398.1 and BP391071.1. This sequence is a reference standard in the RefSeqGene project. On May 31, 2019 this sequence version replaced NM_001033053.2. Transcript Variant: This variant (5) has an alternate 3' sequence, as compared to variant 1. The resulting isoform (5) has a distinct and shorter C-terminus, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GCTGGACCAG 
ACAACTCTGA GTGATGAGAT GAGGCAGGAA CTGAGGGCCC TGGAGCAGGA GAAACCTCAG 
CTGCTCATCT TCAGCAGACG GAAACCAAGT GTGATGACCC CTACTGAGGG CCTGGATACG 
GGAGAGATGA GTAATAGCAC ATCCTCACTC AAGCGGCAGA GACTCGGATC AGAGAGGGCG 
GCTTCCCATG TTGCTCAGGC TAATCTCAAA CTCCTGGACG TGAGCAAGAT CTTCCCAATT 
GCTGAGATTG CAGGCAAGAG CCACGAGGAA AGCTCCCCAG AGGTAGTACC GGTGGAACTC 
TTGTGCGTGC CTTCTCCTGC CTCTCAAGGG GACCTGCATA CGAAGCCTTT GGGGACTGAC 
GATGACTTCT GGGGCCCCAC GGGGCCTGTG GCTACTGAGG TAGTTGACAA AGAAAAGAAC 
TTGTACCGAG TTCACTTCCC TGTAGCTGGC TCCTACCGCT GGCCCAACAC GGGTCTCTGC 
TTTGTGATGA GAGAAGCGGT GACCGTTGAG ATTGAATTCT GTGTGTGGGA CCAGTTCCTG 
GGTGAGATCA ACCCACAGCA CAGCTGGATG GTGGCAGGGC CTCTGCTGGA CATCAAGGCT 
GAGCCTGGAG CTGTGGAAGC TGTGCACCTC CCTCACTTTG TGGCTCTCCA AGGGGGCCAT 
GTGGACACAT CCCTGTTCCA AATGGCCCAC TTTAAAGAGG AGGGGATGCT CCTGGAGAAG 
CCAGCCAGGG TGGAGCTGCA TCACATAGTT CTGGAAAACC CCAGCTTCTC CCCCTTGGGA 
GTCCTCCTGA AAATGATCCA TAATGCCCTG CGCTTCATTC CCGTCACCTC TGTGGTGTTG 
CTTTACCACC GCGTCCATCC TGAGGAAGTC ACCTTCCACC TCTACCTGAT CCCAAGTGAC 
TGCTCCATTC GGAAGGCCAT AGATGATCTA GAAATGAAAT TCCAGTTTGT GCGAATCCAC 
AAGCCACCCC CGCTGACCCC ACTTTATATG GGCTGTCGTT ACACTGTGTC TGGGTCTGGT 
TCAGGGATGC TGGAAATACT CCCCAAGGAA CTGGAGCTCT GCTATCGAAG CCCTGGAGAA 
GACCAGCTGT TCTCGGAGTT CTACGTTGGC CACTTGGGAT CAGGGATCAG GCTGCAAGTG 
AAAGACAAGA AAGATGAGAC TCTGGTGTGG GAGGCCTTGG TGAAACCAGG AAGGAACACC 
AGCCAGCCGT GGAACCTCAG GTGCAACAGA GACGCCAGGA GATACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001028225.1
CDS	553..4680
Translation	MAGGAWGRLACYLEFLKKEELKEFQLLLANKAHSRSSSGETPAQPEKTSGMEVASYLVAQYGEQRAWDLALHTWEQMGLRSLCAQAQEGAGHSPSFPYSPSEPHLGSPSQPTSTAVLMPWIHELPAGCTQGSERRVLRQLPDTSGRRWREISASLLYQALPSSPDHESPSQESPNAPTSTAVLGSWGSPPQPSLAPREQEAPGTQWPLDETSGIYYTEIREREREKSEKGRPPWAAVVGTPPQAHTSLQPHHHPWEPSVRESLCSTWPWKNEDFNQKFTQLLLLQRPHPRSQDPLVKRSWPDYVEENRGHLIEIRDLFGPGLDTQEPRIVILQGAAGIGKSTLARQVKEAWGRGQLYGDRFQHVFYFSCRELAQSKVVSLAELIGKDGTATPAPIRQILSRPERLLFILDGVDEPGWVLQEPSSELCLHWSQPQPADALLGSLLGKTILPEASFLITARTTALQNLIPSLEQARWVEVLGFSESSRKEYFYRYFTDERQAIRAFRLVKSNKELWALCLVPWVSWLACTCLMQQMKRKEKLTLTSKTTTTLCLHYLAQALQAQPLGPQLRDLCSLAAEGIWQKKTLFSPDDLRKHGLDGAIISTFLKMGILQEHPIPLSYSFIHLCFQEFFAAMSYVLEDEKGRGKHSNCIIDLEKTLEAYGIHGLFGASTTRFLLGLLSDEGEREMENIFHCRLSQGRNLMQWVPSLQLLLQPHSLESLHCLYETRNKTFLTQVMAHFEEMGMCVETDMELLVCTFCIKFSRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAYWQILFSVLKVTRNLKELDLSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSFNVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVLSASPSLKELDLQQNNLDDVGVRLLCEGLRHPACKLIRLGLDQTTLSDEMRQELRALEQEKPQLLIFSRRKPSVMTPTEGLDTGEMSNSTSSLKRQRLGSERAASHVAQANLKLLDVSKIFPIAEIAGKSHEESSPEVVPVELLCVPSPASQGDLHTKPLGTDDDFWGPTGPVATEVVDKEKNLYRVHFPVAGSYRWPNTGLCFVMREAVTVEIEFCVWDQFLGEINPQHSWMVAGPLLDIKAEPGAVEAVHLPHFVALQGGHVDTSLFQMAHFKEEGMLLEKPARVELHHIVLENPSFSPLGVLLKMIHNALRFIPVTSVVLLYHRVHPEEVTFHLYLIPSDCSIRKAIDDLEMKFQFVRIHKPPPLTPLYMGCRYTVSGSGSGMLEILPKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVWEALVKPGRNTSQPWNLRCNRDARRY

Target ORF information:

RefSeq Version	NM_001033053.3
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001033053.3

ORF Insert Sequence:

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GCTGGACCAG 
ACAACTCTGA GTGATGAGAT GAGGCAGGAA CTGAGGGCCC TGGAGCAGGA GAAACCTCAG 
CTGCTCATCT TCAGCAGACG GAAACCAAGT GTGATGACCC CTACTGAGGG CCTGGATACG 
GGAGAGATGA GTAATAGCAC ATCCTCACTC AAGCGGCAGA GACTCGGATC AGAGAGGGCG 
GCTTCCCATG TTGCTCAGGC TAATCTCAAA CTCCTGGACG TGAGCAAGAT CTTCCCAATT 
GCTGAGATTG CAGGCAAGAG CCACGAGGAA AGCTCCCCAG AGGTAGTACC GGTGGAACTC 
TTGTGCGTGC CTTCTCCTGC CTCTCAAGGG GACCTGCATA CGAAGCCTTT GGGGACTGAC 
GATGACTTCT GGGGCCCCAC GGGGCCTGTG GCTACTGAGG TAGTTGACAA AGAAAAGAAC 
TTGTACCGAG TTCACTTCCC TGTAGCTGGC TCCTACCGCT GGCCCAACAC GGGTCTCTGC 
TTTGTGATGA GAGAAGCGGT GACCGTTGAG ATTGAATTCT GTGTGTGGGA CCAGTTCCTG 
GGTGAGATCA ACCCACAGCA CAGCTGGATG GTGGCAGGGC CTCTGCTGGA CATCAAGGCT 
GAGCCTGGAG CTGTGGAAGC TGTGCACCTC CCTCACTTTG TGGCTCTCCA AGGGGGCCAT 
GTGGACACAT CCCTGTTCCA AATGGCCCAC TTTAAAGAGG AGGGGATGCT CCTGGAGAAG 
CCAGCCAGGG TGGAGCTGCA TCACATAGTT CTGGAAAACC CCAGCTTCTC CCCCTTGGGA 
GTCCTCCTGA AAATGATCCA TAATGCCCTG CGCTTCATTC CCGTCACCTC TGTGGTGTTG 
CTTTACCACC GCGTCCATCC TGAGGAAGTC ACCTTCCACC TCTACCTGAT CCCAAGTGAC 
TGCTCCATTC GGAAGGCCAT AGATGATCTA GAAATGAAAT TCCAGTTTGT GCGAATCCAC 
AAGCCACCCC CGCTGACCCC ACTTTATATG GGCTGTCGTT ACACTGTGTC TGGGTCTGGT 
TCAGGGATGC TGGAAATACT CCCCAAGGAA CTGGAGCTCT GCTATCGAAG CCCTGGAGAA 
GACCAGCTGT TCTCGGAGTT CTACGTTGGC CACTTGGGAT CAGGGATCAG GCTGCAAGTG 
AAAGACAAGA AAGATGAGAC TCTGGTGTGG GAGGCCTTGG TGAAACCAGG AAGGAACACC 
AGCCAGCCGT GGAACCTCAG GTGCAACAGA GACGCCAGGA GATACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP1 ( NM_014922.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_055737.1 Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu25373
Clone ID Related Accession (Same CDS sequence)	NM_014922.5 , NM_014922.4
Accession Version	NM_014922.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4290bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055839.9, AB023143.1 and AI819334.1. On May 31, 2019 this sequence version replaced NM_014922.4. Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region, as compared to variant 1. The encoded isoform 2 is missing an internal segment, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB023143.1, AF310105.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GCTGGACCAG 
ACAACTCTGA GTGATGAGAT GAGGCAGGAA CTGAGGGCCC TGGAGCAGGA GAAACCTCAG 
CTGCTCATCT TCAGCAGACG GAAACCAAGT GTGATGACCC CTACTGAGGG CCTGGATACG 
GGAGAGATGA GTAATAGCAC ATCCTCACTC AAGCGGCAGA GACTCGGATC AGAGAGGGCG 
GCTTCCCATG TTGCTCAGGC TAATCTCAAA CTCCTGGACG TGAGCAAGAT CTTCCCAATT 
GCTGAGATTG CAGAGGAAAG CTCCCCAGAG GTAGTACCGG TGGAACTCTT GTGCGTGCCT 
TCTCCTGCCT CTCAAGGGGA CCTGCATACG AAGCCTTTGG GGACTGACGA TGACTTCTGG 
GGCCCCACGG GGCCTGTGGC TACTGAGGTA GTTGACAAAG AAAAGAACTT GTACCGAGTT 
CACTTCCCTG TAGCTGGCTC CTACCGCTGG CCCAACACGG GTCTCTGCTT TGTGATGAGA 
GAAGCGGTGA CCGTTGAGAT TGAATTCTGT GTGTGGGACC AGTTCCTGGG TGAGATCAAC 
CCACAGCACA GCTGGATGGT GGCAGGGCCT CTGCTGGACA TCAAGGCTGA GCCTGGAGCT 
GTGGAAGCTG TGCACCTCCC TCACTTTGTG GCTCTCCAAG GGGGCCATGT GGACACATCC 
CTGTTCCAAA TGGCCCACTT TAAAGAGGAG GGGATGCTCC TGGAGAAGCC AGCCAGGGTG 
GAGCTGCATC ACATAGTTCT GGAAAACCCC AGCTTCTCCC CCTTGGGAGT CCTCCTGAAA 
ATGATCCATA ATGCCCTGCG CTTCATTCCC GTCACCTCTG TGGTGTTGCT TTACCACCGC 
GTCCATCCTG AGGAAGTCAC CTTCCACCTC TACCTGATCC CAAGTGACTG CTCCATTCGG 
AAGGAACTGG AGCTCTGCTA TCGAAGCCCT GGAGAAGACC AGCTGTTCTC GGAGTTCTAC 
GTTGGCCACT TGGGATCAGG GATCAGGCTG CAAGTGAAAG ACAAGAAAGA TGAGACTCTG 
GTGTGGGAGG CCTTGGTGAA ACCAGGAGAT CTCATGCCTG CAACTACTCT GATCCCTCCA 
GCCCGCATAG CCGTACCTTC ACCTCTGGAT GCCCCGCAGT TGCTGCACTT TGTGGACCAG 
TATCGAGAGC AGCTGATAGC CCGAGTGACA TCGGTGGAGG TTGTCTTGGA CAAACTGCAT 
GGACAGGTGC TGAGCCAGGA GCAGTACGAG AGGGTGCTGG CTGAGAACAC GAGGCCCAGC 
CAGATGCGGA AGCTGTTCAG CTTGAGCCAG TCCTGGGACC GGAAGTGCAA AGATGGACTC 
TACCAAGCCC TGAAGGAGAC CCATCCTCAC CTCATTATGG AACTCTGGGA GAAGGGCAGC 
AAAAAGGGAC TCCTGCCACT CAGCAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055737.1
CDS	553..4842
Translation	MAGGAWGRLACYLEFLKKEELKEFQLLLANKAHSRSSSGETPAQPEKTSGMEVASYLVAQYGEQRAWDLALHTWEQMGLRSLCAQAQEGAGHSPSFPYSPSEPHLGSPSQPTSTAVLMPWIHELPAGCTQGSERRVLRQLPDTSGRRWREISASLLYQALPSSPDHESPSQESPNAPTSTAVLGSWGSPPQPSLAPREQEAPGTQWPLDETSGIYYTEIREREREKSEKGRPPWAAVVGTPPQAHTSLQPHHHPWEPSVRESLCSTWPWKNEDFNQKFTQLLLLQRPHPRSQDPLVKRSWPDYVEENRGHLIEIRDLFGPGLDTQEPRIVILQGAAGIGKSTLARQVKEAWGRGQLYGDRFQHVFYFSCRELAQSKVVSLAELIGKDGTATPAPIRQILSRPERLLFILDGVDEPGWVLQEPSSELCLHWSQPQPADALLGSLLGKTILPEASFLITARTTALQNLIPSLEQARWVEVLGFSESSRKEYFYRYFTDERQAIRAFRLVKSNKELWALCLVPWVSWLACTCLMQQMKRKEKLTLTSKTTTTLCLHYLAQALQAQPLGPQLRDLCSLAAEGIWQKKTLFSPDDLRKHGLDGAIISTFLKMGILQEHPIPLSYSFIHLCFQEFFAAMSYVLEDEKGRGKHSNCIIDLEKTLEAYGIHGLFGASTTRFLLGLLSDEGEREMENIFHCRLSQGRNLMQWVPSLQLLLQPHSLESLHCLYETRNKTFLTQVMAHFEEMGMCVETDMELLVCTFCIKFSRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAYWQILFSVLKVTRNLKELDLSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSFNVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVLSASPSLKELDLQQNNLDDVGVRLLCEGLRHPACKLIRLGLDQTTLSDEMRQELRALEQEKPQLLIFSRRKPSVMTPTEGLDTGEMSNSTSSLKRQRLGSERAASHVAQANLKLLDVSKIFPIAEIAEESSPEVVPVELLCVPSPASQGDLHTKPLGTDDDFWGPTGPVATEVVDKEKNLYRVHFPVAGSYRWPNTGLCFVMREAVTVEIEFCVWDQFLGEINPQHSWMVAGPLLDIKAEPGAVEAVHLPHFVALQGGHVDTSLFQMAHFKEEGMLLEKPARVELHHIVLENPSFSPLGVLLKMIHNALRFIPVTSVVLLYHRVHPEEVTFHLYLIPSDCSIRKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVWEALVKPGDLMPATTLIPPARIAVPSPLDAPQLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQYERVLAENTRPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMELWEKGSKKGLLPLSS

Target ORF information:

RefSeq Version	NM_014922.5
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014922.5

ORF Insert Sequence:

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GCTGGACCAG 
ACAACTCTGA GTGATGAGAT GAGGCAGGAA CTGAGGGCCC TGGAGCAGGA GAAACCTCAG 
CTGCTCATCT TCAGCAGACG GAAACCAAGT GTGATGACCC CTACTGAGGG CCTGGATACG 
GGAGAGATGA GTAATAGCAC ATCCTCACTC AAGCGGCAGA GACTCGGATC AGAGAGGGCG 
GCTTCCCATG TTGCTCAGGC TAATCTCAAA CTCCTGGACG TGAGCAAGAT CTTCCCAATT 
GCTGAGATTG CAGAGGAAAG CTCCCCAGAG GTAGTACCGG TGGAACTCTT GTGCGTGCCT 
TCTCCTGCCT CTCAAGGGGA CCTGCATACG AAGCCTTTGG GGACTGACGA TGACTTCTGG 
GGCCCCACGG GGCCTGTGGC TACTGAGGTA GTTGACAAAG AAAAGAACTT GTACCGAGTT 
CACTTCCCTG TAGCTGGCTC CTACCGCTGG CCCAACACGG GTCTCTGCTT TGTGATGAGA 
GAAGCGGTGA CCGTTGAGAT TGAATTCTGT GTGTGGGACC AGTTCCTGGG TGAGATCAAC 
CCACAGCACA GCTGGATGGT GGCAGGGCCT CTGCTGGACA TCAAGGCTGA GCCTGGAGCT 
GTGGAAGCTG TGCACCTCCC TCACTTTGTG GCTCTCCAAG GGGGCCATGT GGACACATCC 
CTGTTCCAAA TGGCCCACTT TAAAGAGGAG GGGATGCTCC TGGAGAAGCC AGCCAGGGTG 
GAGCTGCATC ACATAGTTCT GGAAAACCCC AGCTTCTCCC CCTTGGGAGT CCTCCTGAAA 
ATGATCCATA ATGCCCTGCG CTTCATTCCC GTCACCTCTG TGGTGTTGCT TTACCACCGC 
GTCCATCCTG AGGAAGTCAC CTTCCACCTC TACCTGATCC CAAGTGACTG CTCCATTCGG 
AAGGAACTGG AGCTCTGCTA TCGAAGCCCT GGAGAAGACC AGCTGTTCTC GGAGTTCTAC 
GTTGGCCACT TGGGATCAGG GATCAGGCTG CAAGTGAAAG ACAAGAAAGA TGAGACTCTG 
GTGTGGGAGG CCTTGGTGAA ACCAGGAGAT CTCATGCCTG CAACTACTCT GATCCCTCCA 
GCCCGCATAG CCGTACCTTC ACCTCTGGAT GCCCCGCAGT TGCTGCACTT TGTGGACCAG 
TATCGAGAGC AGCTGATAGC CCGAGTGACA TCGGTGGAGG TTGTCTTGGA CAAACTGCAT 
GGACAGGTGC TGAGCCAGGA GCAGTACGAG AGGGTGCTGG CTGAGAACAC GAGGCCCAGC 
CAGATGCGGA AGCTGTTCAG CTTGAGCCAG TCCTGGGACC GGAAGTGCAA AGATGGACTC 
TACCAAGCCC TGAAGGAGAC CCATCCTCAC CTCATTATGG AACTCTGGGA GAAGGGCAGC 
AAAAAGGGAC TCCTGCCACT CAGCAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP1 ( NM_014922.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055737.1 Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu25373
Clone ID Related Accession (Same CDS sequence)	NM_014922.5 , NM_014922.4
Accession Version	NM_014922.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4290bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055839.9, AB023143.1 and AI819334.1. On Dec 14, 2006 this sequence version replaced NM_014922.3. Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region, as compared to variant 1. The encoded isoform 2 is missing an internal segment, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB023143.1, AF310105.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GCTGGACCAG 
ACAACTCTGA GTGATGAGAT GAGGCAGGAA CTGAGGGCCC TGGAGCAGGA GAAACCTCAG 
CTGCTCATCT TCAGCAGACG GAAACCAAGT GTGATGACCC CTACTGAGGG CCTGGATACG 
GGAGAGATGA GTAATAGCAC ATCCTCACTC AAGCGGCAGA GACTCGGATC AGAGAGGGCG 
GCTTCCCATG TTGCTCAGGC TAATCTCAAA CTCCTGGACG TGAGCAAGAT CTTCCCAATT 
GCTGAGATTG CAGAGGAAAG CTCCCCAGAG GTAGTACCGG TGGAACTCTT GTGCGTGCCT 
TCTCCTGCCT CTCAAGGGGA CCTGCATACG AAGCCTTTGG GGACTGACGA TGACTTCTGG 
GGCCCCACGG GGCCTGTGGC TACTGAGGTA GTTGACAAAG AAAAGAACTT GTACCGAGTT 
CACTTCCCTG TAGCTGGCTC CTACCGCTGG CCCAACACGG GTCTCTGCTT TGTGATGAGA 
GAAGCGGTGA CCGTTGAGAT TGAATTCTGT GTGTGGGACC AGTTCCTGGG TGAGATCAAC 
CCACAGCACA GCTGGATGGT GGCAGGGCCT CTGCTGGACA TCAAGGCTGA GCCTGGAGCT 
GTGGAAGCTG TGCACCTCCC TCACTTTGTG GCTCTCCAAG GGGGCCATGT GGACACATCC 
CTGTTCCAAA TGGCCCACTT TAAAGAGGAG GGGATGCTCC TGGAGAAGCC AGCCAGGGTG 
GAGCTGCATC ACATAGTTCT GGAAAACCCC AGCTTCTCCC CCTTGGGAGT CCTCCTGAAA 
ATGATCCATA ATGCCCTGCG CTTCATTCCC GTCACCTCTG TGGTGTTGCT TTACCACCGC 
GTCCATCCTG AGGAAGTCAC CTTCCACCTC TACCTGATCC CAAGTGACTG CTCCATTCGG 
AAGGAACTGG AGCTCTGCTA TCGAAGCCCT GGAGAAGACC AGCTGTTCTC GGAGTTCTAC 
GTTGGCCACT TGGGATCAGG GATCAGGCTG CAAGTGAAAG ACAAGAAAGA TGAGACTCTG 
GTGTGGGAGG CCTTGGTGAA ACCAGGAGAT CTCATGCCTG CAACTACTCT GATCCCTCCA 
GCCCGCATAG CCGTACCTTC ACCTCTGGAT GCCCCGCAGT TGCTGCACTT TGTGGACCAG 
TATCGAGAGC AGCTGATAGC CCGAGTGACA TCGGTGGAGG TTGTCTTGGA CAAACTGCAT 
GGACAGGTGC TGAGCCAGGA GCAGTACGAG AGGGTGCTGG CTGAGAACAC GAGGCCCAGC 
CAGATGCGGA AGCTGTTCAG CTTGAGCCAG TCCTGGGACC GGAAGTGCAA AGATGGACTC 
TACCAAGCCC TGAAGGAGAC CCATCCTCAC CTCATTATGG AACTCTGGGA GAAGGGCAGC 
AAAAAGGGAC TCCTGCCACT CAGCAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055737.1
CDS	556..4845
Translation	MAGGAWGRLACYLEFLKKEELKEFQLLLANKAHSRSSSGETPAQPEKTSGMEVASYLVAQYGEQRAWDLALHTWEQMGLRSLCAQAQEGAGHSPSFPYSPSEPHLGSPSQPTSTAVLMPWIHELPAGCTQGSERRVLRQLPDTSGRRWREISASLLYQALPSSPDHESPSQESPNAPTSTAVLGSWGSPPQPSLAPREQEAPGTQWPLDETSGIYYTEIREREREKSEKGRPPWAAVVGTPPQAHTSLQPHHHPWEPSVRESLCSTWPWKNEDFNQKFTQLLLLQRPHPRSQDPLVKRSWPDYVEENRGHLIEIRDLFGPGLDTQEPRIVILQGAAGIGKSTLARQVKEAWGRGQLYGDRFQHVFYFSCRELAQSKVVSLAELIGKDGTATPAPIRQILSRPERLLFILDGVDEPGWVLQEPSSELCLHWSQPQPADALLGSLLGKTILPEASFLITARTTALQNLIPSLEQARWVEVLGFSESSRKEYFYRYFTDERQAIRAFRLVKSNKELWALCLVPWVSWLACTCLMQQMKRKEKLTLTSKTTTTLCLHYLAQALQAQPLGPQLRDLCSLAAEGIWQKKTLFSPDDLRKHGLDGAIISTFLKMGILQEHPIPLSYSFIHLCFQEFFAAMSYVLEDEKGRGKHSNCIIDLEKTLEAYGIHGLFGASTTRFLLGLLSDEGEREMENIFHCRLSQGRNLMQWVPSLQLLLQPHSLESLHCLYETRNKTFLTQVMAHFEEMGMCVETDMELLVCTFCIKFSRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAYWQILFSVLKVTRNLKELDLSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSFNVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVLSASPSLKELDLQQNNLDDVGVRLLCEGLRHPACKLIRLGLDQTTLSDEMRQELRALEQEKPQLLIFSRRKPSVMTPTEGLDTGEMSNSTSSLKRQRLGSERAASHVAQANLKLLDVSKIFPIAEIAEESSPEVVPVELLCVPSPASQGDLHTKPLGTDDDFWGPTGPVATEVVDKEKNLYRVHFPVAGSYRWPNTGLCFVMREAVTVEIEFCVWDQFLGEINPQHSWMVAGPLLDIKAEPGAVEAVHLPHFVALQGGHVDTSLFQMAHFKEEGMLLEKPARVELHHIVLENPSFSPLGVLLKMIHNALRFIPVTSVVLLYHRVHPEEVTFHLYLIPSDCSIRKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVWEALVKPGDLMPATTLIPPARIAVPSPLDAPQLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQYERVLAENTRPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMELWEKGSKKGLLPLSS

Target ORF information:

RefSeq Version	NM_014922.4
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014922.4

ORF Insert Sequence:

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GCTGGACCAG 
ACAACTCTGA GTGATGAGAT GAGGCAGGAA CTGAGGGCCC TGGAGCAGGA GAAACCTCAG 
CTGCTCATCT TCAGCAGACG GAAACCAAGT GTGATGACCC CTACTGAGGG CCTGGATACG 
GGAGAGATGA GTAATAGCAC ATCCTCACTC AAGCGGCAGA GACTCGGATC AGAGAGGGCG 
GCTTCCCATG TTGCTCAGGC TAATCTCAAA CTCCTGGACG TGAGCAAGAT CTTCCCAATT 
GCTGAGATTG CAGAGGAAAG CTCCCCAGAG GTAGTACCGG TGGAACTCTT GTGCGTGCCT 
TCTCCTGCCT CTCAAGGGGA CCTGCATACG AAGCCTTTGG GGACTGACGA TGACTTCTGG 
GGCCCCACGG GGCCTGTGGC TACTGAGGTA GTTGACAAAG AAAAGAACTT GTACCGAGTT 
CACTTCCCTG TAGCTGGCTC CTACCGCTGG CCCAACACGG GTCTCTGCTT TGTGATGAGA 
GAAGCGGTGA CCGTTGAGAT TGAATTCTGT GTGTGGGACC AGTTCCTGGG TGAGATCAAC 
CCACAGCACA GCTGGATGGT GGCAGGGCCT CTGCTGGACA TCAAGGCTGA GCCTGGAGCT 
GTGGAAGCTG TGCACCTCCC TCACTTTGTG GCTCTCCAAG GGGGCCATGT GGACACATCC 
CTGTTCCAAA TGGCCCACTT TAAAGAGGAG GGGATGCTCC TGGAGAAGCC AGCCAGGGTG 
GAGCTGCATC ACATAGTTCT GGAAAACCCC AGCTTCTCCC CCTTGGGAGT CCTCCTGAAA 
ATGATCCATA ATGCCCTGCG CTTCATTCCC GTCACCTCTG TGGTGTTGCT TTACCACCGC 
GTCCATCCTG AGGAAGTCAC CTTCCACCTC TACCTGATCC CAAGTGACTG CTCCATTCGG 
AAGGAACTGG AGCTCTGCTA TCGAAGCCCT GGAGAAGACC AGCTGTTCTC GGAGTTCTAC 
GTTGGCCACT TGGGATCAGG GATCAGGCTG CAAGTGAAAG ACAAGAAAGA TGAGACTCTG 
GTGTGGGAGG CCTTGGTGAA ACCAGGAGAT CTCATGCCTG CAACTACTCT GATCCCTCCA 
GCCCGCATAG CCGTACCTTC ACCTCTGGAT GCCCCGCAGT TGCTGCACTT TGTGGACCAG 
TATCGAGAGC AGCTGATAGC CCGAGTGACA TCGGTGGAGG TTGTCTTGGA CAAACTGCAT 
GGACAGGTGC TGAGCCAGGA GCAGTACGAG AGGGTGCTGG CTGAGAACAC GAGGCCCAGC 
CAGATGCGGA AGCTGTTCAG CTTGAGCCAG TCCTGGGACC GGAAGTGCAA AGATGGACTC 
TACCAAGCCC TGAAGGAGAC CCATCCTCAC CTCATTATGG AACTCTGGGA GAAGGGCAGC 
AAAAAGGGAC TCCTGCCACT CAGCAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP1 ( NM_033007.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_127500.1 Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 4, mRNA.

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CloneID	OHu25556
Clone ID Related Accession (Same CDS sequence)	NM_033007.4 , NM_033007.3
Accession Version	NM_033007.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4200bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-10
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 1 isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055839.9, AF229061.1, AB023143.1 and AI819334.1. On May 31, 2019 this sequence version replaced NM_033007.3. Transcript Variant: This variant (4) lacks two in-frame exons in the coding region, as compared to variant 1. The encoded isoform 4 is missing two internal segments, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF229061.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GAAACCAAGT 
GTGATGACCC CTACTGAGGG CCTGGATACG GGAGAGATGA GTAATAGCAC ATCCTCACTC 
AAGCGGCAGA GACTCGGATC AGAGAGGGCG GCTTCCCATG TTGCTCAGGC TAATCTCAAA 
CTCCTGGACG TGAGCAAGAT CTTCCCAATT GCTGAGATTG CAGAGGAAAG CTCCCCAGAG 
GTAGTACCGG TGGAACTCTT GTGCGTGCCT TCTCCTGCCT CTCAAGGGGA CCTGCATACG 
AAGCCTTTGG GGACTGACGA TGACTTCTGG GGCCCCACGG GGCCTGTGGC TACTGAGGTA 
GTTGACAAAG AAAAGAACTT GTACCGAGTT CACTTCCCTG TAGCTGGCTC CTACCGCTGG 
CCCAACACGG GTCTCTGCTT TGTGATGAGA GAAGCGGTGA CCGTTGAGAT TGAATTCTGT 
GTGTGGGACC AGTTCCTGGG TGAGATCAAC CCACAGCACA GCTGGATGGT GGCAGGGCCT 
CTGCTGGACA TCAAGGCTGA GCCTGGAGCT GTGGAAGCTG TGCACCTCCC TCACTTTGTG 
GCTCTCCAAG GGGGCCATGT GGACACATCC CTGTTCCAAA TGGCCCACTT TAAAGAGGAG 
GGGATGCTCC TGGAGAAGCC AGCCAGGGTG GAGCTGCATC ACATAGTTCT GGAAAACCCC 
AGCTTCTCCC CCTTGGGAGT CCTCCTGAAA ATGATCCATA ATGCCCTGCG CTTCATTCCC 
GTCACCTCTG TGGTGTTGCT TTACCACCGC GTCCATCCTG AGGAAGTCAC CTTCCACCTC 
TACCTGATCC CAAGTGACTG CTCCATTCGG AAGGAACTGG AGCTCTGCTA TCGAAGCCCT 
GGAGAAGACC AGCTGTTCTC GGAGTTCTAC GTTGGCCACT TGGGATCAGG GATCAGGCTG 
CAAGTGAAAG ACAAGAAAGA TGAGACTCTG GTGTGGGAGG CCTTGGTGAA ACCAGGAGAT 
CTCATGCCTG CAACTACTCT GATCCCTCCA GCCCGCATAG CCGTACCTTC ACCTCTGGAT 
GCCCCGCAGT TGCTGCACTT TGTGGACCAG TATCGAGAGC AGCTGATAGC CCGAGTGACA 
TCGGTGGAGG TTGTCTTGGA CAAACTGCAT GGACAGGTGC TGAGCCAGGA GCAGTACGAG 
AGGGTGCTGG CTGAGAACAC GAGGCCCAGC CAGATGCGGA AGCTGTTCAG CTTGAGCCAG 
TCCTGGGACC GGAAGTGCAA AGATGGACTC TACCAAGCCC TGAAGGAGAC CCATCCTCAC 
CTCATTATGG AACTCTGGGA GAAGGGCAGC AAAAAGGGAC TCCTGCCACT CAGCAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_127500.1
CDS	553..4752
Translation	MAGGAWGRLACYLEFLKKEELKEFQLLLANKAHSRSSSGETPAQPEKTSGMEVASYLVAQYGEQRAWDLALHTWEQMGLRSLCAQAQEGAGHSPSFPYSPSEPHLGSPSQPTSTAVLMPWIHELPAGCTQGSERRVLRQLPDTSGRRWREISASLLYQALPSSPDHESPSQESPNAPTSTAVLGSWGSPPQPSLAPREQEAPGTQWPLDETSGIYYTEIREREREKSEKGRPPWAAVVGTPPQAHTSLQPHHHPWEPSVRESLCSTWPWKNEDFNQKFTQLLLLQRPHPRSQDPLVKRSWPDYVEENRGHLIEIRDLFGPGLDTQEPRIVILQGAAGIGKSTLARQVKEAWGRGQLYGDRFQHVFYFSCRELAQSKVVSLAELIGKDGTATPAPIRQILSRPERLLFILDGVDEPGWVLQEPSSELCLHWSQPQPADALLGSLLGKTILPEASFLITARTTALQNLIPSLEQARWVEVLGFSESSRKEYFYRYFTDERQAIRAFRLVKSNKELWALCLVPWVSWLACTCLMQQMKRKEKLTLTSKTTTTLCLHYLAQALQAQPLGPQLRDLCSLAAEGIWQKKTLFSPDDLRKHGLDGAIISTFLKMGILQEHPIPLSYSFIHLCFQEFFAAMSYVLEDEKGRGKHSNCIIDLEKTLEAYGIHGLFGASTTRFLLGLLSDEGEREMENIFHCRLSQGRNLMQWVPSLQLLLQPHSLESLHCLYETRNKTFLTQVMAHFEEMGMCVETDMELLVCTFCIKFSRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAYWQILFSVLKVTRNLKELDLSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSFNVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVLSASPSLKELDLQQNNLDDVGVRLLCEGLRHPACKLIRLGKPSVMTPTEGLDTGEMSNSTSSLKRQRLGSERAASHVAQANLKLLDVSKIFPIAEIAEESSPEVVPVELLCVPSPASQGDLHTKPLGTDDDFWGPTGPVATEVVDKEKNLYRVHFPVAGSYRWPNTGLCFVMREAVTVEIEFCVWDQFLGEINPQHSWMVAGPLLDIKAEPGAVEAVHLPHFVALQGGHVDTSLFQMAHFKEEGMLLEKPARVELHHIVLENPSFSPLGVLLKMIHNALRFIPVTSVVLLYHRVHPEEVTFHLYLIPSDCSIRKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVWEALVKPGDLMPATTLIPPARIAVPSPLDAPQLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQYERVLAENTRPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMELWEKGSKKGLLPLSS

Target ORF information:

RefSeq Version	NM_033007.4
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033007.4

ORF Insert Sequence:

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GAAACCAAGT 
GTGATGACCC CTACTGAGGG CCTGGATACG GGAGAGATGA GTAATAGCAC ATCCTCACTC 
AAGCGGCAGA GACTCGGATC AGAGAGGGCG GCTTCCCATG TTGCTCAGGC TAATCTCAAA 
CTCCTGGACG TGAGCAAGAT CTTCCCAATT GCTGAGATTG CAGAGGAAAG CTCCCCAGAG 
GTAGTACCGG TGGAACTCTT GTGCGTGCCT TCTCCTGCCT CTCAAGGGGA CCTGCATACG 
AAGCCTTTGG GGACTGACGA TGACTTCTGG GGCCCCACGG GGCCTGTGGC TACTGAGGTA 
GTTGACAAAG AAAAGAACTT GTACCGAGTT CACTTCCCTG TAGCTGGCTC CTACCGCTGG 
CCCAACACGG GTCTCTGCTT TGTGATGAGA GAAGCGGTGA CCGTTGAGAT TGAATTCTGT 
GTGTGGGACC AGTTCCTGGG TGAGATCAAC CCACAGCACA GCTGGATGGT GGCAGGGCCT 
CTGCTGGACA TCAAGGCTGA GCCTGGAGCT GTGGAAGCTG TGCACCTCCC TCACTTTGTG 
GCTCTCCAAG GGGGCCATGT GGACACATCC CTGTTCCAAA TGGCCCACTT TAAAGAGGAG 
GGGATGCTCC TGGAGAAGCC AGCCAGGGTG GAGCTGCATC ACATAGTTCT GGAAAACCCC 
AGCTTCTCCC CCTTGGGAGT CCTCCTGAAA ATGATCCATA ATGCCCTGCG CTTCATTCCC 
GTCACCTCTG TGGTGTTGCT TTACCACCGC GTCCATCCTG AGGAAGTCAC CTTCCACCTC 
TACCTGATCC CAAGTGACTG CTCCATTCGG AAGGAACTGG AGCTCTGCTA TCGAAGCCCT 
GGAGAAGACC AGCTGTTCTC GGAGTTCTAC GTTGGCCACT TGGGATCAGG GATCAGGCTG 
CAAGTGAAAG ACAAGAAAGA TGAGACTCTG GTGTGGGAGG CCTTGGTGAA ACCAGGAGAT 
CTCATGCCTG CAACTACTCT GATCCCTCCA GCCCGCATAG CCGTACCTTC ACCTCTGGAT 
GCCCCGCAGT TGCTGCACTT TGTGGACCAG TATCGAGAGC AGCTGATAGC CCGAGTGACA 
TCGGTGGAGG TTGTCTTGGA CAAACTGCAT GGACAGGTGC TGAGCCAGGA GCAGTACGAG 
AGGGTGCTGG CTGAGAACAC GAGGCCCAGC CAGATGCGGA AGCTGTTCAG CTTGAGCCAG 
TCCTGGGACC GGAAGTGCAA AGATGGACTC TACCAAGCCC TGAAGGAGAC CCATCCTCAC 
CTCATTATGG AACTCTGGGA GAAGGGCAGC AAAAAGGGAC TCCTGCCACT CAGCAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP1 ( NM_033007.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_127500.1 Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 4, mRNA.

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CloneID	OHu25556
Clone ID Related Accession (Same CDS sequence)	NM_033007.4 , NM_033007.3
Accession Version	NM_033007.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4200bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 1 isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055839.9, AF229061.1, AB023143.1 and AI819334.1. On Dec 14, 2006 this sequence version replaced NM_033007.2. Transcript Variant: This variant (4) lacks two in-frame exons in the coding region, as compared to variant 1. The encoded isoform 4 is missing two internal segments, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF229061.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GAAACCAAGT 
GTGATGACCC CTACTGAGGG CCTGGATACG GGAGAGATGA GTAATAGCAC ATCCTCACTC 
AAGCGGCAGA GACTCGGATC AGAGAGGGCG GCTTCCCATG TTGCTCAGGC TAATCTCAAA 
CTCCTGGACG TGAGCAAGAT CTTCCCAATT GCTGAGATTG CAGAGGAAAG CTCCCCAGAG 
GTAGTACCGG TGGAACTCTT GTGCGTGCCT TCTCCTGCCT CTCAAGGGGA CCTGCATACG 
AAGCCTTTGG GGACTGACGA TGACTTCTGG GGCCCCACGG GGCCTGTGGC TACTGAGGTA 
GTTGACAAAG AAAAGAACTT GTACCGAGTT CACTTCCCTG TAGCTGGCTC CTACCGCTGG 
CCCAACACGG GTCTCTGCTT TGTGATGAGA GAAGCGGTGA CCGTTGAGAT TGAATTCTGT 
GTGTGGGACC AGTTCCTGGG TGAGATCAAC CCACAGCACA GCTGGATGGT GGCAGGGCCT 
CTGCTGGACA TCAAGGCTGA GCCTGGAGCT GTGGAAGCTG TGCACCTCCC TCACTTTGTG 
GCTCTCCAAG GGGGCCATGT GGACACATCC CTGTTCCAAA TGGCCCACTT TAAAGAGGAG 
GGGATGCTCC TGGAGAAGCC AGCCAGGGTG GAGCTGCATC ACATAGTTCT GGAAAACCCC 
AGCTTCTCCC CCTTGGGAGT CCTCCTGAAA ATGATCCATA ATGCCCTGCG CTTCATTCCC 
GTCACCTCTG TGGTGTTGCT TTACCACCGC GTCCATCCTG AGGAAGTCAC CTTCCACCTC 
TACCTGATCC CAAGTGACTG CTCCATTCGG AAGGAACTGG AGCTCTGCTA TCGAAGCCCT 
GGAGAAGACC AGCTGTTCTC GGAGTTCTAC GTTGGCCACT TGGGATCAGG GATCAGGCTG 
CAAGTGAAAG ACAAGAAAGA TGAGACTCTG GTGTGGGAGG CCTTGGTGAA ACCAGGAGAT 
CTCATGCCTG CAACTACTCT GATCCCTCCA GCCCGCATAG CCGTACCTTC ACCTCTGGAT 
GCCCCGCAGT TGCTGCACTT TGTGGACCAG TATCGAGAGC AGCTGATAGC CCGAGTGACA 
TCGGTGGAGG TTGTCTTGGA CAAACTGCAT GGACAGGTGC TGAGCCAGGA GCAGTACGAG 
AGGGTGCTGG CTGAGAACAC GAGGCCCAGC CAGATGCGGA AGCTGTTCAG CTTGAGCCAG 
TCCTGGGACC GGAAGTGCAA AGATGGACTC TACCAAGCCC TGAAGGAGAC CCATCCTCAC 
CTCATTATGG AACTCTGGGA GAAGGGCAGC AAAAAGGGAC TCCTGCCACT CAGCAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_127500.1
CDS	556..4755
Translation	MAGGAWGRLACYLEFLKKEELKEFQLLLANKAHSRSSSGETPAQPEKTSGMEVASYLVAQYGEQRAWDLALHTWEQMGLRSLCAQAQEGAGHSPSFPYSPSEPHLGSPSQPTSTAVLMPWIHELPAGCTQGSERRVLRQLPDTSGRRWREISASLLYQALPSSPDHESPSQESPNAPTSTAVLGSWGSPPQPSLAPREQEAPGTQWPLDETSGIYYTEIREREREKSEKGRPPWAAVVGTPPQAHTSLQPHHHPWEPSVRESLCSTWPWKNEDFNQKFTQLLLLQRPHPRSQDPLVKRSWPDYVEENRGHLIEIRDLFGPGLDTQEPRIVILQGAAGIGKSTLARQVKEAWGRGQLYGDRFQHVFYFSCRELAQSKVVSLAELIGKDGTATPAPIRQILSRPERLLFILDGVDEPGWVLQEPSSELCLHWSQPQPADALLGSLLGKTILPEASFLITARTTALQNLIPSLEQARWVEVLGFSESSRKEYFYRYFTDERQAIRAFRLVKSNKELWALCLVPWVSWLACTCLMQQMKRKEKLTLTSKTTTTLCLHYLAQALQAQPLGPQLRDLCSLAAEGIWQKKTLFSPDDLRKHGLDGAIISTFLKMGILQEHPIPLSYSFIHLCFQEFFAAMSYVLEDEKGRGKHSNCIIDLEKTLEAYGIHGLFGASTTRFLLGLLSDEGEREMENIFHCRLSQGRNLMQWVPSLQLLLQPHSLESLHCLYETRNKTFLTQVMAHFEEMGMCVETDMELLVCTFCIKFSRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAYWQILFSVLKVTRNLKELDLSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSFNVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVLSASPSLKELDLQQNNLDDVGVRLLCEGLRHPACKLIRLGKPSVMTPTEGLDTGEMSNSTSSLKRQRLGSERAASHVAQANLKLLDVSKIFPIAEIAEESSPEVVPVELLCVPSPASQGDLHTKPLGTDDDFWGPTGPVATEVVDKEKNLYRVHFPVAGSYRWPNTGLCFVMREAVTVEIEFCVWDQFLGEINPQHSWMVAGPLLDIKAEPGAVEAVHLPHFVALQGGHVDTSLFQMAHFKEEGMLLEKPARVELHHIVLENPSFSPLGVLLKMIHNALRFIPVTSVVLLYHRVHPEEVTFHLYLIPSDCSIRKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVWEALVKPGDLMPATTLIPPARIAVPSPLDAPQLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQYERVLAENTRPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMELWEKGSKKGLLPLSS

Target ORF information:

RefSeq Version	NM_033007.3
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033007.3

ORF Insert Sequence:

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GAAACCAAGT 
GTGATGACCC CTACTGAGGG CCTGGATACG GGAGAGATGA GTAATAGCAC ATCCTCACTC 
AAGCGGCAGA GACTCGGATC AGAGAGGGCG GCTTCCCATG TTGCTCAGGC TAATCTCAAA 
CTCCTGGACG TGAGCAAGAT CTTCCCAATT GCTGAGATTG CAGAGGAAAG CTCCCCAGAG 
GTAGTACCGG TGGAACTCTT GTGCGTGCCT TCTCCTGCCT CTCAAGGGGA CCTGCATACG 
AAGCCTTTGG GGACTGACGA TGACTTCTGG GGCCCCACGG GGCCTGTGGC TACTGAGGTA 
GTTGACAAAG AAAAGAACTT GTACCGAGTT CACTTCCCTG TAGCTGGCTC CTACCGCTGG 
CCCAACACGG GTCTCTGCTT TGTGATGAGA GAAGCGGTGA CCGTTGAGAT TGAATTCTGT 
GTGTGGGACC AGTTCCTGGG TGAGATCAAC CCACAGCACA GCTGGATGGT GGCAGGGCCT 
CTGCTGGACA TCAAGGCTGA GCCTGGAGCT GTGGAAGCTG TGCACCTCCC TCACTTTGTG 
GCTCTCCAAG GGGGCCATGT GGACACATCC CTGTTCCAAA TGGCCCACTT TAAAGAGGAG 
GGGATGCTCC TGGAGAAGCC AGCCAGGGTG GAGCTGCATC ACATAGTTCT GGAAAACCCC 
AGCTTCTCCC CCTTGGGAGT CCTCCTGAAA ATGATCCATA ATGCCCTGCG CTTCATTCCC 
GTCACCTCTG TGGTGTTGCT TTACCACCGC GTCCATCCTG AGGAAGTCAC CTTCCACCTC 
TACCTGATCC CAAGTGACTG CTCCATTCGG AAGGAACTGG AGCTCTGCTA TCGAAGCCCT 
GGAGAAGACC AGCTGTTCTC GGAGTTCTAC GTTGGCCACT TGGGATCAGG GATCAGGCTG 
CAAGTGAAAG ACAAGAAAGA TGAGACTCTG GTGTGGGAGG CCTTGGTGAA ACCAGGAGAT 
CTCATGCCTG CAACTACTCT GATCCCTCCA GCCCGCATAG CCGTACCTTC ACCTCTGGAT 
GCCCCGCAGT TGCTGCACTT TGTGGACCAG TATCGAGAGC AGCTGATAGC CCGAGTGACA 
TCGGTGGAGG TTGTCTTGGA CAAACTGCAT GGACAGGTGC TGAGCCAGGA GCAGTACGAG 
AGGGTGCTGG CTGAGAACAC GAGGCCCAGC CAGATGCGGA AGCTGTTCAG CTTGAGCCAG 
TCCTGGGACC GGAAGTGCAA AGATGGACTC TACCAAGCCC TGAAGGAGAC CCATCCTCAC 
CTCATTATGG AACTCTGGGA GAAGGGCAGC AAAAAGGGAC TCCTGCCACT CAGCAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP1 ( NM_033006.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_127499.1 Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu25557
Clone ID Related Accession (Same CDS sequence)	NM_033006.3 , NM_033006.4
Accession Version	NM_033006.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4332bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 1 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055839.9, AF229062.1, AB023143.1 and AI819334.1. On Dec 14, 2006 this sequence version replaced NM_033006.2. Transcript Variant: This variant (3) lacks an in-frame exon in the middle coding region, as compared to variant 1. The encoded isoform 3 is missing an internal segment, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF229062.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GAAACCAAGT 
GTGATGACCC CTACTGAGGG CCTGGATACG GGAGAGATGA GTAATAGCAC ATCCTCACTC 
AAGCGGCAGA GACTCGGATC AGAGAGGGCG GCTTCCCATG TTGCTCAGGC TAATCTCAAA 
CTCCTGGACG TGAGCAAGAT CTTCCCAATT GCTGAGATTG CAGAGGAAAG CTCCCCAGAG 
GTAGTACCGG TGGAACTCTT GTGCGTGCCT TCTCCTGCCT CTCAAGGGGA CCTGCATACG 
AAGCCTTTGG GGACTGACGA TGACTTCTGG GGCCCCACGG GGCCTGTGGC TACTGAGGTA 
GTTGACAAAG AAAAGAACTT GTACCGAGTT CACTTCCCTG TAGCTGGCTC CTACCGCTGG 
CCCAACACGG GTCTCTGCTT TGTGATGAGA GAAGCGGTGA CCGTTGAGAT TGAATTCTGT 
GTGTGGGACC AGTTCCTGGG TGAGATCAAC CCACAGCACA GCTGGATGGT GGCAGGGCCT 
CTGCTGGACA TCAAGGCTGA GCCTGGAGCT GTGGAAGCTG TGCACCTCCC TCACTTTGTG 
GCTCTCCAAG GGGGCCATGT GGACACATCC CTGTTCCAAA TGGCCCACTT TAAAGAGGAG 
GGGATGCTCC TGGAGAAGCC AGCCAGGGTG GAGCTGCATC ACATAGTTCT GGAAAACCCC 
AGCTTCTCCC CCTTGGGAGT CCTCCTGAAA ATGATCCATA ATGCCCTGCG CTTCATTCCC 
GTCACCTCTG TGGTGTTGCT TTACCACCGC GTCCATCCTG AGGAAGTCAC CTTCCACCTC 
TACCTGATCC CAAGTGACTG CTCCATTCGG AAGGCCATAG ATGATCTAGA AATGAAATTC 
CAGTTTGTGC GAATCCACAA GCCACCCCCG CTGACCCCAC TTTATATGGG CTGTCGTTAC 
ACTGTGTCTG GGTCTGGTTC AGGGATGCTG GAAATACTCC CCAAGGAACT GGAGCTCTGC 
TATCGAAGCC CTGGAGAAGA CCAGCTGTTC TCGGAGTTCT ACGTTGGCCA CTTGGGATCA 
GGGATCAGGC TGCAAGTGAA AGACAAGAAA GATGAGACTC TGGTGTGGGA GGCCTTGGTG 
AAACCAGGAG ATCTCATGCC TGCAACTACT CTGATCCCTC CAGCCCGCAT AGCCGTACCT 
TCACCTCTGG ATGCCCCGCA GTTGCTGCAC TTTGTGGACC AGTATCGAGA GCAGCTGATA 
GCCCGAGTGA CATCGGTGGA GGTTGTCTTG GACAAACTGC ATGGACAGGT GCTGAGCCAG 
GAGCAGTACG AGAGGGTGCT GGCTGAGAAC ACGAGGCCCA GCCAGATGCG GAAGCTGTTC 
AGCTTGAGCC AGTCCTGGGA CCGGAAGTGC AAAGATGGAC TCTACCAAGC CCTGAAGGAG 
ACCCATCCTC ACCTCATTAT GGAACTCTGG GAGAAGGGCA GCAAAAAGGG ACTCCTGCCA 
CTCAGCAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_127499.1
CDS	556..4887
Translation	MAGGAWGRLACYLEFLKKEELKEFQLLLANKAHSRSSSGETPAQPEKTSGMEVASYLVAQYGEQRAWDLALHTWEQMGLRSLCAQAQEGAGHSPSFPYSPSEPHLGSPSQPTSTAVLMPWIHELPAGCTQGSERRVLRQLPDTSGRRWREISASLLYQALPSSPDHESPSQESPNAPTSTAVLGSWGSPPQPSLAPREQEAPGTQWPLDETSGIYYTEIREREREKSEKGRPPWAAVVGTPPQAHTSLQPHHHPWEPSVRESLCSTWPWKNEDFNQKFTQLLLLQRPHPRSQDPLVKRSWPDYVEENRGHLIEIRDLFGPGLDTQEPRIVILQGAAGIGKSTLARQVKEAWGRGQLYGDRFQHVFYFSCRELAQSKVVSLAELIGKDGTATPAPIRQILSRPERLLFILDGVDEPGWVLQEPSSELCLHWSQPQPADALLGSLLGKTILPEASFLITARTTALQNLIPSLEQARWVEVLGFSESSRKEYFYRYFTDERQAIRAFRLVKSNKELWALCLVPWVSWLACTCLMQQMKRKEKLTLTSKTTTTLCLHYLAQALQAQPLGPQLRDLCSLAAEGIWQKKTLFSPDDLRKHGLDGAIISTFLKMGILQEHPIPLSYSFIHLCFQEFFAAMSYVLEDEKGRGKHSNCIIDLEKTLEAYGIHGLFGASTTRFLLGLLSDEGEREMENIFHCRLSQGRNLMQWVPSLQLLLQPHSLESLHCLYETRNKTFLTQVMAHFEEMGMCVETDMELLVCTFCIKFSRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAYWQILFSVLKVTRNLKELDLSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSFNVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVLSASPSLKELDLQQNNLDDVGVRLLCEGLRHPACKLIRLGKPSVMTPTEGLDTGEMSNSTSSLKRQRLGSERAASHVAQANLKLLDVSKIFPIAEIAEESSPEVVPVELLCVPSPASQGDLHTKPLGTDDDFWGPTGPVATEVVDKEKNLYRVHFPVAGSYRWPNTGLCFVMREAVTVEIEFCVWDQFLGEINPQHSWMVAGPLLDIKAEPGAVEAVHLPHFVALQGGHVDTSLFQMAHFKEEGMLLEKPARVELHHIVLENPSFSPLGVLLKMIHNALRFIPVTSVVLLYHRVHPEEVTFHLYLIPSDCSIRKAIDDLEMKFQFVRIHKPPPLTPLYMGCRYTVSGSGSGMLEILPKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVWEALVKPGDLMPATTLIPPARIAVPSPLDAPQLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQYERVLAENTRPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMELWEKGSKKGLLPLSS

Target ORF information:

RefSeq Version	NM_033006.3
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033006.3

ORF Insert Sequence:

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GAAACCAAGT 
GTGATGACCC CTACTGAGGG CCTGGATACG GGAGAGATGA GTAATAGCAC ATCCTCACTC 
AAGCGGCAGA GACTCGGATC AGAGAGGGCG GCTTCCCATG TTGCTCAGGC TAATCTCAAA 
CTCCTGGACG TGAGCAAGAT CTTCCCAATT GCTGAGATTG CAGAGGAAAG CTCCCCAGAG 
GTAGTACCGG TGGAACTCTT GTGCGTGCCT TCTCCTGCCT CTCAAGGGGA CCTGCATACG 
AAGCCTTTGG GGACTGACGA TGACTTCTGG GGCCCCACGG GGCCTGTGGC TACTGAGGTA 
GTTGACAAAG AAAAGAACTT GTACCGAGTT CACTTCCCTG TAGCTGGCTC CTACCGCTGG 
CCCAACACGG GTCTCTGCTT TGTGATGAGA GAAGCGGTGA CCGTTGAGAT TGAATTCTGT 
GTGTGGGACC AGTTCCTGGG TGAGATCAAC CCACAGCACA GCTGGATGGT GGCAGGGCCT 
CTGCTGGACA TCAAGGCTGA GCCTGGAGCT GTGGAAGCTG TGCACCTCCC TCACTTTGTG 
GCTCTCCAAG GGGGCCATGT GGACACATCC CTGTTCCAAA TGGCCCACTT TAAAGAGGAG 
GGGATGCTCC TGGAGAAGCC AGCCAGGGTG GAGCTGCATC ACATAGTTCT GGAAAACCCC 
AGCTTCTCCC CCTTGGGAGT CCTCCTGAAA ATGATCCATA ATGCCCTGCG CTTCATTCCC 
GTCACCTCTG TGGTGTTGCT TTACCACCGC GTCCATCCTG AGGAAGTCAC CTTCCACCTC 
TACCTGATCC CAAGTGACTG CTCCATTCGG AAGGCCATAG ATGATCTAGA AATGAAATTC 
CAGTTTGTGC GAATCCACAA GCCACCCCCG CTGACCCCAC TTTATATGGG CTGTCGTTAC 
ACTGTGTCTG GGTCTGGTTC AGGGATGCTG GAAATACTCC CCAAGGAACT GGAGCTCTGC 
TATCGAAGCC CTGGAGAAGA CCAGCTGTTC TCGGAGTTCT ACGTTGGCCA CTTGGGATCA 
GGGATCAGGC TGCAAGTGAA AGACAAGAAA GATGAGACTC TGGTGTGGGA GGCCTTGGTG 
AAACCAGGAG ATCTCATGCC TGCAACTACT CTGATCCCTC CAGCCCGCAT AGCCGTACCT 
TCACCTCTGG ATGCCCCGCA GTTGCTGCAC TTTGTGGACC AGTATCGAGA GCAGCTGATA 
GCCCGAGTGA CATCGGTGGA GGTTGTCTTG GACAAACTGC ATGGACAGGT GCTGAGCCAG 
GAGCAGTACG AGAGGGTGCT GGCTGAGAAC ACGAGGCCCA GCCAGATGCG GAAGCTGTTC 
AGCTTGAGCC AGTCCTGGGA CCGGAAGTGC AAAGATGGAC TCTACCAAGC CCTGAAGGAG 
ACCCATCCTC ACCTCATTAT GGAACTCTGG GAGAAGGGCA GCAAAAAGGG ACTCCTGCCA 
CTCAGCAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP1 ( NM_033006.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_127499.1 Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 3, mRNA.

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CloneID	OHu25557
Clone ID Related Accession (Same CDS sequence)	NM_033006.3 , NM_033006.4
Accession Version	NM_033006.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4332bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-10
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 1 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC055839.9, AF229062.1, AB023143.1 and AI819334.1. On May 31, 2019 this sequence version replaced NM_033006.3. Transcript Variant: This variant (3) lacks an in-frame exon in the middle coding region, as compared to variant 1. The encoded isoform 3 is missing an internal segment, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF229062.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GAAACCAAGT 
GTGATGACCC CTACTGAGGG CCTGGATACG GGAGAGATGA GTAATAGCAC ATCCTCACTC 
AAGCGGCAGA GACTCGGATC AGAGAGGGCG GCTTCCCATG TTGCTCAGGC TAATCTCAAA 
CTCCTGGACG TGAGCAAGAT CTTCCCAATT GCTGAGATTG CAGAGGAAAG CTCCCCAGAG 
GTAGTACCGG TGGAACTCTT GTGCGTGCCT TCTCCTGCCT CTCAAGGGGA CCTGCATACG 
AAGCCTTTGG GGACTGACGA TGACTTCTGG GGCCCCACGG GGCCTGTGGC TACTGAGGTA 
GTTGACAAAG AAAAGAACTT GTACCGAGTT CACTTCCCTG TAGCTGGCTC CTACCGCTGG 
CCCAACACGG GTCTCTGCTT TGTGATGAGA GAAGCGGTGA CCGTTGAGAT TGAATTCTGT 
GTGTGGGACC AGTTCCTGGG TGAGATCAAC CCACAGCACA GCTGGATGGT GGCAGGGCCT 
CTGCTGGACA TCAAGGCTGA GCCTGGAGCT GTGGAAGCTG TGCACCTCCC TCACTTTGTG 
GCTCTCCAAG GGGGCCATGT GGACACATCC CTGTTCCAAA TGGCCCACTT TAAAGAGGAG 
GGGATGCTCC TGGAGAAGCC AGCCAGGGTG GAGCTGCATC ACATAGTTCT GGAAAACCCC 
AGCTTCTCCC CCTTGGGAGT CCTCCTGAAA ATGATCCATA ATGCCCTGCG CTTCATTCCC 
GTCACCTCTG TGGTGTTGCT TTACCACCGC GTCCATCCTG AGGAAGTCAC CTTCCACCTC 
TACCTGATCC CAAGTGACTG CTCCATTCGG AAGGCCATAG ATGATCTAGA AATGAAATTC 
CAGTTTGTGC GAATCCACAA GCCACCCCCG CTGACCCCAC TTTATATGGG CTGTCGTTAC 
ACTGTGTCTG GGTCTGGTTC AGGGATGCTG GAAATACTCC CCAAGGAACT GGAGCTCTGC 
TATCGAAGCC CTGGAGAAGA CCAGCTGTTC TCGGAGTTCT ACGTTGGCCA CTTGGGATCA 
GGGATCAGGC TGCAAGTGAA AGACAAGAAA GATGAGACTC TGGTGTGGGA GGCCTTGGTG 
AAACCAGGAG ATCTCATGCC TGCAACTACT CTGATCCCTC CAGCCCGCAT AGCCGTACCT 
TCACCTCTGG ATGCCCCGCA GTTGCTGCAC TTTGTGGACC AGTATCGAGA GCAGCTGATA 
GCCCGAGTGA CATCGGTGGA GGTTGTCTTG GACAAACTGC ATGGACAGGT GCTGAGCCAG 
GAGCAGTACG AGAGGGTGCT GGCTGAGAAC ACGAGGCCCA GCCAGATGCG GAAGCTGTTC 
AGCTTGAGCC AGTCCTGGGA CCGGAAGTGC AAAGATGGAC TCTACCAAGC CCTGAAGGAG 
ACCCATCCTC ACCTCATTAT GGAACTCTGG GAGAAGGGCA GCAAAAAGGG ACTCCTGCCA 
CTCAGCAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_127499.1
CDS	553..4884
Translation	MAGGAWGRLACYLEFLKKEELKEFQLLLANKAHSRSSSGETPAQPEKTSGMEVASYLVAQYGEQRAWDLALHTWEQMGLRSLCAQAQEGAGHSPSFPYSPSEPHLGSPSQPTSTAVLMPWIHELPAGCTQGSERRVLRQLPDTSGRRWREISASLLYQALPSSPDHESPSQESPNAPTSTAVLGSWGSPPQPSLAPREQEAPGTQWPLDETSGIYYTEIREREREKSEKGRPPWAAVVGTPPQAHTSLQPHHHPWEPSVRESLCSTWPWKNEDFNQKFTQLLLLQRPHPRSQDPLVKRSWPDYVEENRGHLIEIRDLFGPGLDTQEPRIVILQGAAGIGKSTLARQVKEAWGRGQLYGDRFQHVFYFSCRELAQSKVVSLAELIGKDGTATPAPIRQILSRPERLLFILDGVDEPGWVLQEPSSELCLHWSQPQPADALLGSLLGKTILPEASFLITARTTALQNLIPSLEQARWVEVLGFSESSRKEYFYRYFTDERQAIRAFRLVKSNKELWALCLVPWVSWLACTCLMQQMKRKEKLTLTSKTTTTLCLHYLAQALQAQPLGPQLRDLCSLAAEGIWQKKTLFSPDDLRKHGLDGAIISTFLKMGILQEHPIPLSYSFIHLCFQEFFAAMSYVLEDEKGRGKHSNCIIDLEKTLEAYGIHGLFGASTTRFLLGLLSDEGEREMENIFHCRLSQGRNLMQWVPSLQLLLQPHSLESLHCLYETRNKTFLTQVMAHFEEMGMCVETDMELLVCTFCIKFSRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAYWQILFSVLKVTRNLKELDLSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSFNVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVLSASPSLKELDLQQNNLDDVGVRLLCEGLRHPACKLIRLGKPSVMTPTEGLDTGEMSNSTSSLKRQRLGSERAASHVAQANLKLLDVSKIFPIAEIAEESSPEVVPVELLCVPSPASQGDLHTKPLGTDDDFWGPTGPVATEVVDKEKNLYRVHFPVAGSYRWPNTGLCFVMREAVTVEIEFCVWDQFLGEINPQHSWMVAGPLLDIKAEPGAVEAVHLPHFVALQGGHVDTSLFQMAHFKEEGMLLEKPARVELHHIVLENPSFSPLGVLLKMIHNALRFIPVTSVVLLYHRVHPEEVTFHLYLIPSDCSIRKAIDDLEMKFQFVRIHKPPPLTPLYMGCRYTVSGSGSGMLEILPKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVWEALVKPGDLMPATTLIPPARIAVPSPLDAPQLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQYERVLAENTRPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMELWEKGSKKGLLPLSS

Target ORF information:

RefSeq Version	NM_033006.4
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 1 (NLRP1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033006.4

ORF Insert Sequence:

ATGGCTGGCG GAGCCTGGGG CCGCCTGGCC TGTTACTTGG AGTTCCTGAA GAAGGAGGAG 
CTGAAGGAGT TCCAGCTTCT GCTCGCCAAT AAAGCGCACT CCAGGAGCTC TTCGGGTGAG 
ACACCCGCTC AGCCAGAGAA GACGAGTGGC ATGGAGGTGG CCTCGTACCT GGTGGCTCAG 
TATGGGGAGC AGCGGGCCTG GGACCTAGCC CTCCATACCT GGGAGCAGAT GGGGCTGAGG 
TCACTGTGCG CCCAAGCCCA GGAAGGGGCA GGCCACTCTC CCTCATTCCC CTACAGCCCA 
AGTGAACCCC ACCTGGGGTC TCCCAGCCAA CCCACCTCCA CCGCAGTGCT AATGCCCTGG 
ATCCATGAAT TGCCGGCGGG GTGCACCCAG GGCTCAGAGA GAAGGGTTTT GAGACAGCTG 
CCTGACACAT CTGGACGCCG CTGGAGAGAA ATCTCTGCCT CACTCCTCTA CCAAGCTCTT 
CCAAGCTCCC CAGACCATGA GTCTCCAAGC CAGGAGTCAC CCAACGCCCC CACATCCACA 
GCAGTGCTGG GGAGCTGGGG ATCCCCACCT CAGCCCAGCC TAGCACCCAG AGAGCAGGAG 
GCTCCTGGGA CCCAATGGCC TCTGGATGAA ACGTCAGGAA TTTACTACAC AGAAATCAGA 
GAAAGAGAGA GAGAGAAATC AGAGAAAGGC AGGCCCCCAT GGGCAGCGGT GGTAGGAACG 
CCCCCACAGG CGCACACCAG CCTACAGCCC CACCACCACC CATGGGAGCC TTCTGTGAGA 
GAGAGCCTCT GTTCCACATG GCCCTGGAAA AATGAGGATT TTAACCAAAA ATTCACACAG 
CTGCTACTTC TACAAAGACC TCACCCCAGA AGCCAAGATC CCCTGGTCAA GAGAAGCTGG 
CCTGATTATG TGGAGGAGAA TCGAGGACAT TTAATTGAGA TCAGAGACTT ATTTGGCCCA 
GGCCTGGATA CCCAAGAACC TCGCATAGTC ATACTGCAGG GGGCTGCTGG AATTGGGAAG 
TCAACACTGG CCAGGCAGGT GAAGGAAGCC TGGGGGAGAG GCCAGCTGTA TGGGGACCGC 
TTCCAGCATG TCTTCTACTT CAGCTGCAGA GAGCTGGCCC AGTCCAAGGT GGTGAGTCTC 
GCTGAGCTCA TCGGAAAAGA TGGGACAGCC ACTCCGGCTC CCATTAGACA GATCCTGTCT 
AGGCCAGAGC GGCTGCTCTT CATCCTCGAT GGTGTAGATG AGCCAGGATG GGTCTTGCAG 
GAGCCGAGTT CTGAGCTCTG TCTGCACTGG AGCCAGCCAC AGCCGGCGGA TGCACTGCTG 
GGCAGTTTGC TGGGGAAAAC TATACTTCCC GAGGCATCCT TCCTGATCAC GGCTCGGACC 
ACAGCTCTGC AGAACCTCAT TCCTTCTTTG GAGCAGGCAC GTTGGGTAGA GGTCCTGGGG 
TTCTCTGAGT CCAGCAGGAA GGAATATTTC TACAGATATT TCACAGATGA AAGGCAAGCA 
ATTAGAGCCT TTAGGTTGGT CAAATCAAAC AAAGAGCTCT GGGCCCTGTG TCTTGTGCCC 
TGGGTGTCCT GGCTGGCCTG CACTTGCCTG ATGCAGCAGA TGAAGCGGAA GGAAAAACTC 
ACACTGACTT CCAAGACCAC CACAACCCTC TGTCTACATT ACCTTGCCCA GGCTCTCCAA 
GCTCAGCCAT TGGGACCCCA GCTCAGAGAC CTCTGCTCTC TGGCTGCTGA GGGCATCTGG 
CAAAAAAAGA CCCTTTTCAG TCCAGATGAC CTCAGGAAGC ATGGGTTAGA TGGGGCCATC 
ATCTCCACCT TCTTGAAGAT GGGTATTCTT CAAGAGCACC CCATCCCTCT GAGCTACAGC 
TTCATTCACC TCTGTTTCCA AGAGTTCTTT GCAGCAATGT CCTATGTCTT GGAGGATGAG 
AAGGGGAGAG GTAAACATTC TAATTGCATC ATAGATTTGG AAAAGACGCT AGAAGCATAT 
GGAATACATG GCCTGTTTGG GGCATCAACC ACACGTTTCC TATTGGGCCT GTTAAGTGAT 
GAGGGGGAGA GAGAGATGGA GAACATCTTT CACTGCCGGC TGTCTCAGGG GAGGAACCTG 
ATGCAGTGGG TCCCGTCCCT GCAGCTGCTG CTGCAGCCAC ACTCTCTGGA GTCCCTCCAC 
TGCTTGTACG AGACTCGGAA CAAAACGTTC CTGACACAAG TGATGGCCCA TTTCGAAGAA 
ATGGGCATGT GTGTAGAAAC AGACATGGAG CTCTTAGTGT GCACTTTCTG CATTAAATTC 
AGCCGCCACG TGAAGAAGCT TCAGCTGATT GAGGGCAGGC AGCACAGATC AACATGGAGC 
CCCACCATGG TAGTCCTGTT CAGGTGGGTC CCAGTCACAG ATGCCTATTG GCAGATTCTC 
TTCTCCGTCC TCAAGGTCAC CAGAAACCTG AAGGAGCTGG ACCTAAGTGG AAACTCGCTG 
AGCCACTCTG CAGTGAAGAG TCTTTGTAAG ACCCTGAGAC GCCCTCGCTG CCTCCTGGAG 
ACCCTGCGGT TGGCTGGCTG TGGCCTCACA GCTGAGGACT GCAAGGACCT TGCCTTTGGG 
CTGAGAGCCA ACCAGACCCT GACCGAGCTG GACCTGAGCT TCAATGTGCT CACGGATGCT 
GGAGCCAAAC ACCTTTGCCA GAGACTGAGA CAGCCGAGCT GCAAGCTACA GCGACTGCAG 
CTGGTCAGCT GTGGCCTCAC GTCTGACTGC TGCCAGGACC TGGCCTCTGT GCTTAGTGCC 
AGCCCCAGCC TGAAGGAGCT AGACCTGCAG CAGAACAACC TGGATGACGT TGGCGTGCGA 
CTGCTCTGTG AGGGGCTCAG GCATCCTGCC TGCAAACTCA TACGCCTGGG GAAACCAAGT 
GTGATGACCC CTACTGAGGG CCTGGATACG GGAGAGATGA GTAATAGCAC ATCCTCACTC 
AAGCGGCAGA GACTCGGATC AGAGAGGGCG GCTTCCCATG TTGCTCAGGC TAATCTCAAA 
CTCCTGGACG TGAGCAAGAT CTTCCCAATT GCTGAGATTG CAGAGGAAAG CTCCCCAGAG 
GTAGTACCGG TGGAACTCTT GTGCGTGCCT TCTCCTGCCT CTCAAGGGGA CCTGCATACG 
AAGCCTTTGG GGACTGACGA TGACTTCTGG GGCCCCACGG GGCCTGTGGC TACTGAGGTA 
GTTGACAAAG AAAAGAACTT GTACCGAGTT CACTTCCCTG TAGCTGGCTC CTACCGCTGG 
CCCAACACGG GTCTCTGCTT TGTGATGAGA GAAGCGGTGA CCGTTGAGAT TGAATTCTGT 
GTGTGGGACC AGTTCCTGGG TGAGATCAAC CCACAGCACA GCTGGATGGT GGCAGGGCCT 
CTGCTGGACA TCAAGGCTGA GCCTGGAGCT GTGGAAGCTG TGCACCTCCC TCACTTTGTG 
GCTCTCCAAG GGGGCCATGT GGACACATCC CTGTTCCAAA TGGCCCACTT TAAAGAGGAG 
GGGATGCTCC TGGAGAAGCC AGCCAGGGTG GAGCTGCATC ACATAGTTCT GGAAAACCCC 
AGCTTCTCCC CCTTGGGAGT CCTCCTGAAA ATGATCCATA ATGCCCTGCG CTTCATTCCC 
GTCACCTCTG TGGTGTTGCT TTACCACCGC GTCCATCCTG AGGAAGTCAC CTTCCACCTC 
TACCTGATCC CAAGTGACTG CTCCATTCGG AAGGCCATAG ATGATCTAGA AATGAAATTC 
CAGTTTGTGC GAATCCACAA GCCACCCCCG CTGACCCCAC TTTATATGGG CTGTCGTTAC 
ACTGTGTCTG GGTCTGGTTC AGGGATGCTG GAAATACTCC CCAAGGAACT GGAGCTCTGC 
TATCGAAGCC CTGGAGAAGA CCAGCTGTTC TCGGAGTTCT ACGTTGGCCA CTTGGGATCA 
GGGATCAGGC TGCAAGTGAA AGACAAGAAA GATGAGACTC TGGTGTGGGA GGCCTTGGTG 
AAACCAGGAG ATCTCATGCC TGCAACTACT CTGATCCCTC CAGCCCGCAT AGCCGTACCT 
TCACCTCTGG ATGCCCCGCA GTTGCTGCAC TTTGTGGACC AGTATCGAGA GCAGCTGATA 
GCCCGAGTGA CATCGGTGGA GGTTGTCTTG GACAAACTGC ATGGACAGGT GCTGAGCCAG 
GAGCAGTACG AGAGGGTGCT GGCTGAGAAC ACGAGGCCCA GCCAGATGCG GAAGCTGTTC 
AGCTTGAGCC AGTCCTGGGA CCGGAAGTGC AAAGATGGAC TCTACCAAGC CCTGAAGGAG 
ACCCATCCTC ACCTCATTAT GGAACTCTGG GAGAAGGGCA GCAAAAAGGG ACTCCTGCCA 
CTCAGCAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	NLRP1
Entrez Gene ID	22861
Full Name	NLR family pyrin domain containing 1
Synonyms	AIADK,CARD7,CIDED,CLR17.1,DEFCAP,DEFCAP-L/S,MSPC,NAC,NALP1,PP1044,SLEV1,VAMAS1
General protein information	Preferred Names NLR family pyrin domain containing 1 Names NACHT, LRR and PYD domains-containing protein 1 NACHT, LRR and PYD containing protein 1 NACHT, leucine rich repeat and PYD (pyrin domain) containing 1 NACHT, leucine rich repeat and PYD containing 1 caspase recruitment domain protein 7 caspase recruitment domain-containing protein 7 death effector filament-forming Ced-4-like apoptosis protein nucleotide-binding domain and caspase recruitment domain nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17p13.2
Summary	This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008].
Disorder MIM:	606636
Disorder Html:	{Vitiligo-associated multiple autoimmune disease susceptibility 1}, 606579 (3); Palmoplantar carcinoma, multiple self-healing, 615255 (3); Autoinflammation with arthritis and dyskeratosis, 617388 (3)

Homo sapiens (human)	NLRP1	NP_127497.1
	NLRP1	NP_001107821.1
Pan troglodytes (chimpanzee)	NLRP1	XP_001167200.2
Canis lupus familiaris (dog)	NLRP1	XP_005619937.1
Bos taurus (cattle)	NLRP1	XP_003587454.2
Mus musculus (house mouse)	Nlrp1b	NP_001035786.1
Rattus norvegicus (Norway rat)	Nlrp1b	XP_006246908.1

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

NLRP1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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