The following EVI2A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EVI2A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu08129 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_001003927.2 , NM_001003927.3 | |
| Accession Version | NM_001003927.2 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 780bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-06-23 | |
| Organism | Homo sapiens(human) | |
| Product | protein EVI2A isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA364537.1, AC134669.4, AK295311.1 and CF135330.1. On Oct 23, 2009 this sequence version replaced NM_001003927.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.87363.1, SRR1660803.87917.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2163105 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGTTGCTTA GGAGTTGGTT TGGAAACAAA GACTTTCAGG CCCTACCTAT ACTAGCTAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001003927.1 |
| CDS | 338..1117 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001003927.2 |
1 | ATGTTGCTTA GGAGTTGGTT TGGAAACAAA GACTTTCAGG CCCTACCTAT ACTAGCTAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu08129 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_001003927.2 , NM_001003927.3 | |
| Accession Version | NM_001003927.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 780bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-29 | |
| Organism | Homo sapiens(human) | |
| Product | protein EVI2A isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK295311.1, AC134669.4 and CF135330.1. On Jun 2, 2019 this sequence version replaced NM_001003927.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.87363.1, SRR1660805.122108.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2163105 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGTTGCTTA GGAGTTGGTT TGGAAACAAA GACTTTCAGG CCCTACCTAT ACTAGCTAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001003927.1 |
| CDS | 211..990 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001003927.3 |
1 | ATGTTGCTTA GGAGTTGGTT TGGAAACAAA GACTTTCAGG CCCTACCTAT ACTAGCTAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu08588 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_014210.4 , NM_014210.3 | |
| Accession Version | NM_014210.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 711bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-28 | |
| Organism | Homo sapiens(human) | |
| Product | protein EVI2A isoform 2 precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK312348.1, BC035572.1, AC134669.4 and CF135330.1. On Jun 2, 2019 this sequence version replaced NM_014210.3. Transcript Variant: This variant (2) lacks a portion of the 5' UTR and 5' coding region, and uses a downstream translational start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. CCDS Note: This CCDS representation uses the 5'-most in-frame start codon, which is conserved in higher primates. An alternative downstream start codon, which is more widely conserved and has a stronger Kozak signal, also exists. It is possible that leaky scanning by ribosomes would allow the downstream start codon to be used, at least some of the time. The use of the downstream start codon would result in a protein that is 4 aa shorter at the N-terminus. Both the longer and shorter N-termini have predicted signal peptides according to SignalP 3.0. There is no experimental evidence showing which start codon is preferentially used in vivo. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.346121.1, SRR1803615.477039.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267782 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## | |
1 | ATGCCCACGG ACATGGAACA CACAGGACAT TACCTACATC TTGCCTTTCT GATGACAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_055025.2 |
| CDS | 139..849 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_014210.4 |
1 | ATGCCCACGG ACATGGAACA CACAGGACAT TACCTACATC TTGCCTTTCT GATGACAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu08588 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_014210.4 , NM_014210.3 | |
| Accession Version | NM_014210.3 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 711bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-02-21 | |
| Organism | Homo sapiens(human) | |
| Product | protein EVI2A isoform 2 precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA364537.1, AC134669.4, AK312348.1, BC035572.1 and CF135330.1. On Oct 23, 2009 this sequence version replaced NM_014210.2. Transcript Variant: This variant (2) lacks a portion of the 5' UTR and 5' coding region, and uses a downstream translational start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. CCDS Note: This CCDS representation uses the 5'-most in-frame start codon, which is conserved in higher primates. An alternative downstream start codon, which is more widely conserved and has a stronger Kozak signal, also exists. It is possible that leaky scanning by ribosomes would allow the downstream start codon to be used, at least some of the time. The use of the downstream start codon would result in a protein that is 4 aa shorter at the N-terminus. Both the longer and shorter N-termini have predicted signal peptides according to SignalP 3.0. There is no experimental evidence showing which start codon is preferentially used in vivo. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.230336.1, SRR1660803.59104.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267782 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGCCCACGG ACATGGAACA CACAGGACAT TACCTACATC TTGCCTTTCT GATGACAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_055025.2 |
| CDS | 266..976 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_014210.3 |
1 | ATGCCCACGG ACATGGAACA CACAGGACAT TACCTACATC TTGCCTTTCT GATGACAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
TAGLN expression is upregulated in NF1-associated malignant peripheral nerve sheath tumors by hypomethylation in its promoter and subpromoter regions. |
Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth. |
Identification and characterization of transcripts from the neurofibromatosis 1 region: the sequence and genomic structure of EVI2 and mapping of other transcripts. |
The human homolog of murine Evi-2 lies between two von Recklinghausen neurofibromatosis translocations. |
Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients. |
