Gene Symbol | AKT2 |
Entrez Gene ID | 208 |
Full Name | AKT serine/threonine kinase 2 |
Synonyms | HIHGHH,PKBB,PKBBETA,PRKBB,RAC-BETA |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Diabetes mellitus, type II, 125853 (3); Hypoinsulinemic hypoglycemia with hemihypertrophy, 240900 (3) |