ENG cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ENG
Entrez Gene ID	2022
Full Name	endoglin
Synonyms	END,HHT1,ORW1
General protein information	Preferred Names endoglin Names endoglin CD105 antigen
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9q34.11
Summary	This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013].
Disorder MIM:	131195
Disorder Html:	Telangiectasia, hereditary hemorrhagic, type 1, 187300 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001114753.2	NP_001108225.1	endoglin isoform 1 precursor
NM_000118.3	NP_000109.1	endoglin isoform 2 precursor
NM_001278138.1	NP_001265067.1	endoglin isoform 3

Pathways from BioSystems

Homologies

Homo sapiens (human)	ENG	NP_001108225.1
Mus musculus (house mouse)	Eng	NP_001139820.1
Pan troglodytes (chimpanzee)	ENG	XP_001143396.3
Gallus gallus (chicken)	ENG	NP_001074356.1
Bos taurus (cattle)	ENG	NP_001069865.1
Rattus norvegicus (Norway rat)	Eng	NP_001010968.1
Xenopus tropicalis (tropical clawed frog)	eng	XP_002935546.2
Canis lupus familiaris (dog)	ENG	XP_851469.2

Gene Ontology

The following ENG gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ENG cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16795	NM_001278138.1 Latest version!	Homo sapiens endoglin (ENG), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu27541	NM_001114753.2 Latest version!	Homo sapiens endoglin (ENG), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu22900	NM_000118.3 Latest version!	Homo sapiens endoglin (ENG), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ENG ( NM_001278138.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001265067.1 Homo sapiens endoglin (ENG), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu16795
Clone ID Related Accession (Same CDS sequence)	NM_001278138.1
Accession Version	NM_001278138.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	endoglin isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK301171.1, BC014271.2 and J05481.1. Transcript Variant: This variant (3) contains a distinct 5' UTR, lacks a portion of the 5' coding region, and uses a downstream in-frame start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK301171.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145245 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGGAAG CCAGCCAGGA CATGGGCCGC ACGCTCGAGT GGCGGCCGCG TACTCCAGCC 
TTGGTCCGGG GCTGCCACTT GGAAGGCGTG GCCGGCCACA AGGAGGCGCA CATCCTGAGG 
GTCCTGCCGG GCCACTCGGC CGGGCCCCGG ACGGTGACGG TGAAGGTGGA ACTGAGCTGC 
GCACCCGGGG ATCTCGATGC CGTCCTCATC CTGCAGGGTC CCCCCTACGT GTCCTGGCTC 
ATCGACGCCA ACCACAACAT GCAGATCTGG ACCACTGGAG AATACTCCTT CAAGATCTTT 
CCAGAGAAAA ACATTCGTGG CTTCAAGCTC CCAGACACAC CTCAAGGCCT CCTGGGGGAG 
GCCCGGATGC TCAATGCCAG CATTGTGGCA TCCTTCGTGG AGCTACCGCT GGCCAGCATT 
GTCTCACTTC ATGCCTCCAG CTGCGGTGGT AGGCTGCAGA CCTCACCCGC ACCGATCCAG 
ACCACTCCTC CCAAGGACAC TTGTAGCCCG GAGCTGCTCA TGTCCTTGAT CCAGACAAAG 
TGTGCCGACG ACGCCATGAC CCTGGTACTA AAGAAAGAGC TTGTTGCGCA TTTGAAGTGC 
ACCATCACGG GCCTGACCTT CTGGGACCCC AGCTGTGAGG CAGAGGACAG GGGTGACAAG 
TTTGTCTTGC GCAGTGCTTA CTCCAGCTGT GGCATGCAGG TGTCAGCAAG TATGATCAGC 
AATGAGGCGG TGGTCAATAT CCTGTCGAGC TCATCACCAC AGCGGAAAAA GGTGCACTGC 
CTCAACATGG ACAGCCTCTC TTTCCAGCTG GGCCTCTACC TCAGCCCACA CTTCCTCCAG 
GCCTCCAACA CCATCGAGCC GGGGCAGCAG AGCTTTGTGC AGGTCAGAGT GTCCCCATCC 
GTCTCCGAGT TCCTGCTCCA GTTAGACAGC TGCCACCTGG ACTTGGGGCC TGAGGGAGGC 
ACCGTGGAAC TCATCCAGGG CCGGGCGGCC AAGGGCAACT GTGTGAGCCT GCTGTCCCCA 
AGCCCCGAGG GTGACCCGCG CTTCAGCTTC CTCCTCCACT TCTACACAGT ACCCATACCC 
AAAACCGGCA CCCTCAGCTG CACGGTAGCC CTGCGTCCCA AGACCGGGTC TCAAGACCAG 
GAAGTCCATA GGACTGTCTT CATGCGCTTG AACATCATCA GCCCTGACCT GTCTGGTTGC 
ACAAGCAAAG GCCTCGTCCT GCCCGCCGTG CTGGGCATCA CCTTTGGTGC CTTCCTCATC 
GGGGCCCTGC TCACTGCTGC ACTCTGGTAC ATCTACTCGC ACACGCGTTC CCCCAGCAAG 
CGGGAGCCCG TGGTGGCGGT GGCTGCCCCG GCCTCCTCGG AGAGCAGCAG CACCAACCAC 
AGCATCGGGA GCACCCAGAG CACCCCCTGC TCCACCAGCA GCATGGCATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001265067.1
CDS	705..2135
Translation	MLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHILRVLPGHSAGPRTVTVKVELSCAPGDLDAVLILQGPPYVSWLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQGLLGEARMLNASIVASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTCSPELLMSLIQTKCADDAMTLVLKKELVAHLKCTITGLTFWDPSCEAEDRGDKFVLRSAYSSCGMQVSASMISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNTIEPGQQSFVQVRVSPSVSEFLLQLDSCHLDLGPEGGTVELIQGRAAKGNCVSLLSPSPEGDPRFSFLLHFYTVPIPKTGTLSCTVALRPKTGSQDQEVHRTVFMRLNIISPDLSGCTSKGLVLPAVLGITFGAFLIGALLTAALWYIYSHTRSPSKREPVVAVAAPASSESSSTNHSIGSTQSTPCSTSSMA

Target ORF information:

RefSeq Version	NM_001278138.1
Organism	Homo sapiens(human)
Definition	Homo sapiens endoglin (ENG), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001278138.1

ORF Insert Sequence:

ATGCTGGAAG CCAGCCAGGA CATGGGCCGC ACGCTCGAGT GGCGGCCGCG TACTCCAGCC 
TTGGTCCGGG GCTGCCACTT GGAAGGCGTG GCCGGCCACA AGGAGGCGCA CATCCTGAGG 
GTCCTGCCGG GCCACTCGGC CGGGCCCCGG ACGGTGACGG TGAAGGTGGA ACTGAGCTGC 
GCACCCGGGG ATCTCGATGC CGTCCTCATC CTGCAGGGTC CCCCCTACGT GTCCTGGCTC 
ATCGACGCCA ACCACAACAT GCAGATCTGG ACCACTGGAG AATACTCCTT CAAGATCTTT 
CCAGAGAAAA ACATTCGTGG CTTCAAGCTC CCAGACACAC CTCAAGGCCT CCTGGGGGAG 
GCCCGGATGC TCAATGCCAG CATTGTGGCA TCCTTCGTGG AGCTACCGCT GGCCAGCATT 
GTCTCACTTC ATGCCTCCAG CTGCGGTGGT AGGCTGCAGA CCTCACCCGC ACCGATCCAG 
ACCACTCCTC CCAAGGACAC TTGTAGCCCG GAGCTGCTCA TGTCCTTGAT CCAGACAAAG 
TGTGCCGACG ACGCCATGAC CCTGGTACTA AAGAAAGAGC TTGTTGCGCA TTTGAAGTGC 
ACCATCACGG GCCTGACCTT CTGGGACCCC AGCTGTGAGG CAGAGGACAG GGGTGACAAG 
TTTGTCTTGC GCAGTGCTTA CTCCAGCTGT GGCATGCAGG TGTCAGCAAG TATGATCAGC 
AATGAGGCGG TGGTCAATAT CCTGTCGAGC TCATCACCAC AGCGGAAAAA GGTGCACTGC 
CTCAACATGG ACAGCCTCTC TTTCCAGCTG GGCCTCTACC TCAGCCCACA CTTCCTCCAG 
GCCTCCAACA CCATCGAGCC GGGGCAGCAG AGCTTTGTGC AGGTCAGAGT GTCCCCATCC 
GTCTCCGAGT TCCTGCTCCA GTTAGACAGC TGCCACCTGG ACTTGGGGCC TGAGGGAGGC 
ACCGTGGAAC TCATCCAGGG CCGGGCGGCC AAGGGCAACT GTGTGAGCCT GCTGTCCCCA 
AGCCCCGAGG GTGACCCGCG CTTCAGCTTC CTCCTCCACT TCTACACAGT ACCCATACCC 
AAAACCGGCA CCCTCAGCTG CACGGTAGCC CTGCGTCCCA AGACCGGGTC TCAAGACCAG 
GAAGTCCATA GGACTGTCTT CATGCGCTTG AACATCATCA GCCCTGACCT GTCTGGTTGC 
ACAAGCAAAG GCCTCGTCCT GCCCGCCGTG CTGGGCATCA CCTTTGGTGC CTTCCTCATC 
GGGGCCCTGC TCACTGCTGC ACTCTGGTAC ATCTACTCGC ACACGCGTTC CCCCAGCAAG 
CGGGAGCCCG TGGTGGCGGT GGCTGCCCCG GCCTCCTCGG AGAGCAGCAG CACCAACCAC 
AGCATCGGGA GCACCCAGAG CACCCCCTGC TCCACCAGCA GCATGGCATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ENG ( NM_001114753.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001108225.1 Homo sapiens endoglin (ENG), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu27541
Clone ID Related Accession (Same CDS sequence)	NM_001114753.2
Accession Version	NM_001114753.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1977bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	endoglin isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB079257.1, X72012.1, BC014271.2 and J05481.1. This sequence is a reference standard in the RefSeqGene project. On May 11, 2013 this sequence version replaced NM_001114753.1. Transcript Variant: This variant (1) encodes the longer isoform (1, also known as L-endoglin). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: J05481.1, SRR1660805.113756.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145245 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGACCGCG GCACGCTCCC TCTGGCTGTT GCCCTGCTGC TGGCCAGCTG CAGCCTCAGC 
CCCACAAGTC TTGCAGAAAC AGTCCATTGT GACCTTCAGC CTGTGGGCCC CGAGAGGGGC 
GAGGTGACAT ATACCACTAG CCAGGTCTCG AAGGGCTGCG TGGCTCAGGC CCCCAATGCC 
ATCCTTGAAG TCCATGTCCT CTTCCTGGAG TTCCCAACGG GCCCGTCACA GCTGGAGCTG 
ACTCTCCAGG CATCCAAGCA AAATGGCACC TGGCCCCGAG AGGTGCTTCT GGTCCTCAGT 
GTAAACAGCA GTGTCTTCCT GCATCTCCAG GCCCTGGGAA TCCCACTGCA CTTGGCCTAC 
AATTCCAGCC TGGTCACCTT CCAAGAGCCC CCGGGGGTCA ACACCACAGA GCTGCCATCC 
TTCCCCAAGA CCCAGATCCT TGAGTGGGCA GCTGAGAGGG GCCCCATCAC CTCTGCTGCT 
GAGCTGAATG ACCCCCAGAG CATCCTCCTC CGACTGGGCC AAGCCCAGGG GTCACTGTCC 
TTCTGCATGC TGGAAGCCAG CCAGGACATG GGCCGCACGC TCGAGTGGCG GCCGCGTACT 
CCAGCCTTGG TCCGGGGCTG CCACTTGGAA GGCGTGGCCG GCCACAAGGA GGCGCACATC 
CTGAGGGTCC TGCCGGGCCA CTCGGCCGGG CCCCGGACGG TGACGGTGAA GGTGGAACTG 
AGCTGCGCAC CCGGGGATCT CGATGCCGTC CTCATCCTGC AGGGTCCCCC CTACGTGTCC 
TGGCTCATCG ACGCCAACCA CAACATGCAG ATCTGGACCA CTGGAGAATA CTCCTTCAAG 
ATCTTTCCAG AGAAAAACAT TCGTGGCTTC AAGCTCCCAG ACACACCTCA AGGCCTCCTG 
GGGGAGGCCC GGATGCTCAA TGCCAGCATT GTGGCATCCT TCGTGGAGCT ACCGCTGGCC 
AGCATTGTCT CACTTCATGC CTCCAGCTGC GGTGGTAGGC TGCAGACCTC ACCCGCACCG 
ATCCAGACCA CTCCTCCCAA GGACACTTGT AGCCCGGAGC TGCTCATGTC CTTGATCCAG 
ACAAAGTGTG CCGACGACGC CATGACCCTG GTACTAAAGA AAGAGCTTGT TGCGCATTTG 
AAGTGCACCA TCACGGGCCT GACCTTCTGG GACCCCAGCT GTGAGGCAGA GGACAGGGGT 
GACAAGTTTG TCTTGCGCAG TGCTTACTCC AGCTGTGGCA TGCAGGTGTC AGCAAGTATG 
ATCAGCAATG AGGCGGTGGT CAATATCCTG TCGAGCTCAT CACCACAGCG GAAAAAGGTG 
CACTGCCTCA ACATGGACAG CCTCTCTTTC CAGCTGGGCC TCTACCTCAG CCCACACTTC 
CTCCAGGCCT CCAACACCAT CGAGCCGGGG CAGCAGAGCT TTGTGCAGGT CAGAGTGTCC 
CCATCCGTCT CCGAGTTCCT GCTCCAGTTA GACAGCTGCC ACCTGGACTT GGGGCCTGAG 
GGAGGCACCG TGGAACTCAT CCAGGGCCGG GCGGCCAAGG GCAACTGTGT GAGCCTGCTG 
TCCCCAAGCC CCGAGGGTGA CCCGCGCTTC AGCTTCCTCC TCCACTTCTA CACAGTACCC 
ATACCCAAAA CCGGCACCCT CAGCTGCACG GTAGCCCTGC GTCCCAAGAC CGGGTCTCAA 
GACCAGGAAG TCCATAGGAC TGTCTTCATG CGCTTGAACA TCATCAGCCC TGACCTGTCT 
GGTTGCACAA GCAAAGGCCT CGTCCTGCCC GCCGTGCTGG GCATCACCTT TGGTGCCTTC 
CTCATCGGGG CCCTGCTCAC TGCTGCACTC TGGTACATCT ACTCGCACAC GCGTTCCCCC 
AGCAAGCGGG AGCCCGTGGT GGCGGTGGCT GCCCCGGCCT CCTCGGAGAG CAGCAGCACC 
AACCACAGCA TCGGGAGCAC CCAGAGCACC CCCTGCTCCA CCAGCAGCAT GGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001108225.1
CDS	419..2395
Translation	MDRGTLPLAVALLLASCSLSPTSLAETVHCDLQPVGPERGEVTYTTSQVSKGCVAQAPNAILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQALGIPLHLAYNSSLVTFQEPPGVNTTELPSFPKTQILEWAAERGPITSAAELNDPQSILLRLGQAQGSLSFCMLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHILRVLPGHSAGPRTVTVKVELSCAPGDLDAVLILQGPPYVSWLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQGLLGEARMLNASIVASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTCSPELLMSLIQTKCADDAMTLVLKKELVAHLKCTITGLTFWDPSCEAEDRGDKFVLRSAYSSCGMQVSASMISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNTIEPGQQSFVQVRVSPSVSEFLLQLDSCHLDLGPEGGTVELIQGRAAKGNCVSLLSPSPEGDPRFSFLLHFYTVPIPKTGTLSCTVALRPKTGSQDQEVHRTVFMRLNIISPDLSGCTSKGLVLPAVLGITFGAFLIGALLTAALWYIYSHTRSPSKREPVVAVAAPASSESSSTNHSIGSTQSTPCSTSSMA

Target ORF information:

RefSeq Version	NM_001114753.2
Organism	Homo sapiens(human)
Definition	Homo sapiens endoglin (ENG), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001114753.2

ORF Insert Sequence:

ATGGACCGCG GCACGCTCCC TCTGGCTGTT GCCCTGCTGC TGGCCAGCTG CAGCCTCAGC 
CCCACAAGTC TTGCAGAAAC AGTCCATTGT GACCTTCAGC CTGTGGGCCC CGAGAGGGGC 
GAGGTGACAT ATACCACTAG CCAGGTCTCG AAGGGCTGCG TGGCTCAGGC CCCCAATGCC 
ATCCTTGAAG TCCATGTCCT CTTCCTGGAG TTCCCAACGG GCCCGTCACA GCTGGAGCTG 
ACTCTCCAGG CATCCAAGCA AAATGGCACC TGGCCCCGAG AGGTGCTTCT GGTCCTCAGT 
GTAAACAGCA GTGTCTTCCT GCATCTCCAG GCCCTGGGAA TCCCACTGCA CTTGGCCTAC 
AATTCCAGCC TGGTCACCTT CCAAGAGCCC CCGGGGGTCA ACACCACAGA GCTGCCATCC 
TTCCCCAAGA CCCAGATCCT TGAGTGGGCA GCTGAGAGGG GCCCCATCAC CTCTGCTGCT 
GAGCTGAATG ACCCCCAGAG CATCCTCCTC CGACTGGGCC AAGCCCAGGG GTCACTGTCC 
TTCTGCATGC TGGAAGCCAG CCAGGACATG GGCCGCACGC TCGAGTGGCG GCCGCGTACT 
CCAGCCTTGG TCCGGGGCTG CCACTTGGAA GGCGTGGCCG GCCACAAGGA GGCGCACATC 
CTGAGGGTCC TGCCGGGCCA CTCGGCCGGG CCCCGGACGG TGACGGTGAA GGTGGAACTG 
AGCTGCGCAC CCGGGGATCT CGATGCCGTC CTCATCCTGC AGGGTCCCCC CTACGTGTCC 
TGGCTCATCG ACGCCAACCA CAACATGCAG ATCTGGACCA CTGGAGAATA CTCCTTCAAG 
ATCTTTCCAG AGAAAAACAT TCGTGGCTTC AAGCTCCCAG ACACACCTCA AGGCCTCCTG 
GGGGAGGCCC GGATGCTCAA TGCCAGCATT GTGGCATCCT TCGTGGAGCT ACCGCTGGCC 
AGCATTGTCT CACTTCATGC CTCCAGCTGC GGTGGTAGGC TGCAGACCTC ACCCGCACCG 
ATCCAGACCA CTCCTCCCAA GGACACTTGT AGCCCGGAGC TGCTCATGTC CTTGATCCAG 
ACAAAGTGTG CCGACGACGC CATGACCCTG GTACTAAAGA AAGAGCTTGT TGCGCATTTG 
AAGTGCACCA TCACGGGCCT GACCTTCTGG GACCCCAGCT GTGAGGCAGA GGACAGGGGT 
GACAAGTTTG TCTTGCGCAG TGCTTACTCC AGCTGTGGCA TGCAGGTGTC AGCAAGTATG 
ATCAGCAATG AGGCGGTGGT CAATATCCTG TCGAGCTCAT CACCACAGCG GAAAAAGGTG 
CACTGCCTCA ACATGGACAG CCTCTCTTTC CAGCTGGGCC TCTACCTCAG CCCACACTTC 
CTCCAGGCCT CCAACACCAT CGAGCCGGGG CAGCAGAGCT TTGTGCAGGT CAGAGTGTCC 
CCATCCGTCT CCGAGTTCCT GCTCCAGTTA GACAGCTGCC ACCTGGACTT GGGGCCTGAG 
GGAGGCACCG TGGAACTCAT CCAGGGCCGG GCGGCCAAGG GCAACTGTGT GAGCCTGCTG 
TCCCCAAGCC CCGAGGGTGA CCCGCGCTTC AGCTTCCTCC TCCACTTCTA CACAGTACCC 
ATACCCAAAA CCGGCACCCT CAGCTGCACG GTAGCCCTGC GTCCCAAGAC CGGGTCTCAA 
GACCAGGAAG TCCATAGGAC TGTCTTCATG CGCTTGAACA TCATCAGCCC TGACCTGTCT 
GGTTGCACAA GCAAAGGCCT CGTCCTGCCC GCCGTGCTGG GCATCACCTT TGGTGCCTTC 
CTCATCGGGG CCCTGCTCAC TGCTGCACTC TGGTACATCT ACTCGCACAC GCGTTCCCCC 
AGCAAGCGGG AGCCCGTGGT GGCGGTGGCT GCCCCGGCCT CCTCGGAGAG CAGCAGCACC 
AACCACAGCA TCGGGAGCAC CCAGAGCACC CCCTGCTCCA CCAGCAGCAT GGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ENG ( NM_000118.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000109.1 Homo sapiens endoglin (ENG), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu22900
Clone ID Related Accession (Same CDS sequence)	NM_000118.3
Accession Version	NM_000118.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1878bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	endoglin isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB079257.1, X72012.1 and AL162586.26. This sequence is a reference standard in the RefSeqGene project. On May 11, 2013 this sequence version replaced NM_000118.2. Transcript Variant: This variant (2) has an additional segment in the 3' coding region which includes an earlier stop codon, compared to variant 1. The resulting isoform (2, also known as S-endoglin) has a shorter and distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X72012.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145245 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGACCGCG GCACGCTCCC TCTGGCTGTT GCCCTGCTGC TGGCCAGCTG CAGCCTCAGC 
CCCACAAGTC TTGCAGAAAC AGTCCATTGT GACCTTCAGC CTGTGGGCCC CGAGAGGGGC 
GAGGTGACAT ATACCACTAG CCAGGTCTCG AAGGGCTGCG TGGCTCAGGC CCCCAATGCC 
ATCCTTGAAG TCCATGTCCT CTTCCTGGAG TTCCCAACGG GCCCGTCACA GCTGGAGCTG 
ACTCTCCAGG CATCCAAGCA AAATGGCACC TGGCCCCGAG AGGTGCTTCT GGTCCTCAGT 
GTAAACAGCA GTGTCTTCCT GCATCTCCAG GCCCTGGGAA TCCCACTGCA CTTGGCCTAC 
AATTCCAGCC TGGTCACCTT CCAAGAGCCC CCGGGGGTCA ACACCACAGA GCTGCCATCC 
TTCCCCAAGA CCCAGATCCT TGAGTGGGCA GCTGAGAGGG GCCCCATCAC CTCTGCTGCT 
GAGCTGAATG ACCCCCAGAG CATCCTCCTC CGACTGGGCC AAGCCCAGGG GTCACTGTCC 
TTCTGCATGC TGGAAGCCAG CCAGGACATG GGCCGCACGC TCGAGTGGCG GCCGCGTACT 
CCAGCCTTGG TCCGGGGCTG CCACTTGGAA GGCGTGGCCG GCCACAAGGA GGCGCACATC 
CTGAGGGTCC TGCCGGGCCA CTCGGCCGGG CCCCGGACGG TGACGGTGAA GGTGGAACTG 
AGCTGCGCAC CCGGGGATCT CGATGCCGTC CTCATCCTGC AGGGTCCCCC CTACGTGTCC 
TGGCTCATCG ACGCCAACCA CAACATGCAG ATCTGGACCA CTGGAGAATA CTCCTTCAAG 
ATCTTTCCAG AGAAAAACAT TCGTGGCTTC AAGCTCCCAG ACACACCTCA AGGCCTCCTG 
GGGGAGGCCC GGATGCTCAA TGCCAGCATT GTGGCATCCT TCGTGGAGCT ACCGCTGGCC 
AGCATTGTCT CACTTCATGC CTCCAGCTGC GGTGGTAGGC TGCAGACCTC ACCCGCACCG 
ATCCAGACCA CTCCTCCCAA GGACACTTGT AGCCCGGAGC TGCTCATGTC CTTGATCCAG 
ACAAAGTGTG CCGACGACGC CATGACCCTG GTACTAAAGA AAGAGCTTGT TGCGCATTTG 
AAGTGCACCA TCACGGGCCT GACCTTCTGG GACCCCAGCT GTGAGGCAGA GGACAGGGGT 
GACAAGTTTG TCTTGCGCAG TGCTTACTCC AGCTGTGGCA TGCAGGTGTC AGCAAGTATG 
ATCAGCAATG AGGCGGTGGT CAATATCCTG TCGAGCTCAT CACCACAGCG GAAAAAGGTG 
CACTGCCTCA ACATGGACAG CCTCTCTTTC CAGCTGGGCC TCTACCTCAG CCCACACTTC 
CTCCAGGCCT CCAACACCAT CGAGCCGGGG CAGCAGAGCT TTGTGCAGGT CAGAGTGTCC 
CCATCCGTCT CCGAGTTCCT GCTCCAGTTA GACAGCTGCC ACCTGGACTT GGGGCCTGAG 
GGAGGCACCG TGGAACTCAT CCAGGGCCGG GCGGCCAAGG GCAACTGTGT GAGCCTGCTG 
TCCCCAAGCC CCGAGGGTGA CCCGCGCTTC AGCTTCCTCC TCCACTTCTA CACAGTACCC 
ATACCCAAAA CCGGCACCCT CAGCTGCACG GTAGCCCTGC GTCCCAAGAC CGGGTCTCAA 
GACCAGGAAG TCCATAGGAC TGTCTTCATG CGCTTGAACA TCATCAGCCC TGACCTGTCT 
GGTTGCACAA GCAAAGGCCT CGTCCTGCCC GCCGTGCTGG GCATCACCTT TGGTGCCTTC 
CTCATCGGGG CCCTGCTCAC TGCTGCACTC TGGTACATCT ACTCGCACAC GCGTGAGTAC 
CCCAGGCCCC CACAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000109.1
CDS	419..2296
Translation	MDRGTLPLAVALLLASCSLSPTSLAETVHCDLQPVGPERGEVTYTTSQVSKGCVAQAPNAILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQALGIPLHLAYNSSLVTFQEPPGVNTTELPSFPKTQILEWAAERGPITSAAELNDPQSILLRLGQAQGSLSFCMLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHILRVLPGHSAGPRTVTVKVELSCAPGDLDAVLILQGPPYVSWLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQGLLGEARMLNASIVASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTCSPELLMSLIQTKCADDAMTLVLKKELVAHLKCTITGLTFWDPSCEAEDRGDKFVLRSAYSSCGMQVSASMISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNTIEPGQQSFVQVRVSPSVSEFLLQLDSCHLDLGPEGGTVELIQGRAAKGNCVSLLSPSPEGDPRFSFLLHFYTVPIPKTGTLSCTVALRPKTGSQDQEVHRTVFMRLNIISPDLSGCTSKGLVLPAVLGITFGAFLIGALLTAALWYIYSHTREYPRPPQ

Target ORF information:

RefSeq Version	NM_000118.3
Organism	Homo sapiens(human)
Definition	Homo sapiens endoglin (ENG), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000118.3

ORF Insert Sequence:

ATGGACCGCG GCACGCTCCC TCTGGCTGTT GCCCTGCTGC TGGCCAGCTG CAGCCTCAGC 
CCCACAAGTC TTGCAGAAAC AGTCCATTGT GACCTTCAGC CTGTGGGCCC CGAGAGGGGC 
GAGGTGACAT ATACCACTAG CCAGGTCTCG AAGGGCTGCG TGGCTCAGGC CCCCAATGCC 
ATCCTTGAAG TCCATGTCCT CTTCCTGGAG TTCCCAACGG GCCCGTCACA GCTGGAGCTG 
ACTCTCCAGG CATCCAAGCA AAATGGCACC TGGCCCCGAG AGGTGCTTCT GGTCCTCAGT 
GTAAACAGCA GTGTCTTCCT GCATCTCCAG GCCCTGGGAA TCCCACTGCA CTTGGCCTAC 
AATTCCAGCC TGGTCACCTT CCAAGAGCCC CCGGGGGTCA ACACCACAGA GCTGCCATCC 
TTCCCCAAGA CCCAGATCCT TGAGTGGGCA GCTGAGAGGG GCCCCATCAC CTCTGCTGCT 
GAGCTGAATG ACCCCCAGAG CATCCTCCTC CGACTGGGCC AAGCCCAGGG GTCACTGTCC 
TTCTGCATGC TGGAAGCCAG CCAGGACATG GGCCGCACGC TCGAGTGGCG GCCGCGTACT 
CCAGCCTTGG TCCGGGGCTG CCACTTGGAA GGCGTGGCCG GCCACAAGGA GGCGCACATC 
CTGAGGGTCC TGCCGGGCCA CTCGGCCGGG CCCCGGACGG TGACGGTGAA GGTGGAACTG 
AGCTGCGCAC CCGGGGATCT CGATGCCGTC CTCATCCTGC AGGGTCCCCC CTACGTGTCC 
TGGCTCATCG ACGCCAACCA CAACATGCAG ATCTGGACCA CTGGAGAATA CTCCTTCAAG 
ATCTTTCCAG AGAAAAACAT TCGTGGCTTC AAGCTCCCAG ACACACCTCA AGGCCTCCTG 
GGGGAGGCCC GGATGCTCAA TGCCAGCATT GTGGCATCCT TCGTGGAGCT ACCGCTGGCC 
AGCATTGTCT CACTTCATGC CTCCAGCTGC GGTGGTAGGC TGCAGACCTC ACCCGCACCG 
ATCCAGACCA CTCCTCCCAA GGACACTTGT AGCCCGGAGC TGCTCATGTC CTTGATCCAG 
ACAAAGTGTG CCGACGACGC CATGACCCTG GTACTAAAGA AAGAGCTTGT TGCGCATTTG 
AAGTGCACCA TCACGGGCCT GACCTTCTGG GACCCCAGCT GTGAGGCAGA GGACAGGGGT 
GACAAGTTTG TCTTGCGCAG TGCTTACTCC AGCTGTGGCA TGCAGGTGTC AGCAAGTATG 
ATCAGCAATG AGGCGGTGGT CAATATCCTG TCGAGCTCAT CACCACAGCG GAAAAAGGTG 
CACTGCCTCA ACATGGACAG CCTCTCTTTC CAGCTGGGCC TCTACCTCAG CCCACACTTC 
CTCCAGGCCT CCAACACCAT CGAGCCGGGG CAGCAGAGCT TTGTGCAGGT CAGAGTGTCC 
CCATCCGTCT CCGAGTTCCT GCTCCAGTTA GACAGCTGCC ACCTGGACTT GGGGCCTGAG 
GGAGGCACCG TGGAACTCAT CCAGGGCCGG GCGGCCAAGG GCAACTGTGT GAGCCTGCTG 
TCCCCAAGCC CCGAGGGTGA CCCGCGCTTC AGCTTCCTCC TCCACTTCTA CACAGTACCC 
ATACCCAAAA CCGGCACCCT CAGCTGCACG GTAGCCCTGC GTCCCAAGAC CGGGTCTCAA 
GACCAGGAAG TCCATAGGAC TGTCTTCATG CGCTTGAACA TCATCAGCCC TGACCTGTCT 
GGTTGCACAA GCAAAGGCCT CGTCCTGCCC GCCGTGCTGG GCATCACCTT TGGTGCCTTC 
CTCATCGGGG CCCTGCTCAC TGCTGCACTC TGGTACATCT ACTCGCACAC GCGTGAGTAC 
CCCAGGCCCC CACAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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ENG cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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見積依頼

Eメール

電話

FAX

オンラインフォーム

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