Gene Symbol | AIF1 |
Entrez Gene ID | 199 |
Full Name | allograft inflammatory factor 1 |
Synonyms | AIF-1,IBA1,IRT-1,IRT1 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016]. |
Disorder MIM: |