SLC26A3 cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLC26A3
Entrez Gene ID	1811
Full Name	solute carrier family 26 member 3
Synonyms	CLD,DRA
General protein information	Preferred Names solute carrier family 26 member 3 Names chloride anion exchanger down-regulated in adenoma protein solute carrier family 26 (anion exchanger), member 3
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: 7 Map Location: 7q22.3-q31.1
Summary	The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea. [provided by RefSeq, Oct 2008].
Disorder MIM:	126650
Disorder Html:	Diarrhea 1, secretory chloride, congenital, 214700 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_000111.2	NP_000102.1	chloride anion exchanger
NM_000111.3	NP_000102.1	chloride anion exchanger
XM_011515867.2	XP_011514169.1	chloride anion exchanger isoform X1
XM_011515867.1	XP_011514169.1	chloride anion exchanger isoform X1

Pathways from BioSystems

Homologies

	SLC26A3	XP_001090155.2
Gallus gallus (chicken)	SLC26A3	NP_001186373.1
Homo sapiens (human)	SLC26A3	NP_000102.1
Mus musculus (house mouse)	Slc26a3	NP_067328.1
Rattus norvegicus (Norway rat)	Slc26a3	NP_446207.1
Pan troglodytes (chimpanzee)	SLC26A3	XP_527858.2
Bos taurus (cattle)	SLC26A3	NP_001077145.1
Caenorhabditis elegans (roundworm)	sulp-6	NP_491138.2
Xenopus tropicalis (tropical clawed frog)	LOC101731072	XP_004913063.1
Canis lupus familiaris (dog)	SLC26A3	XP_540380.3
Danio rerio (zebrafish)	slc26a3	NP_001129155.1
Danio rerio (zebrafish)	si:dkey-31f5.1	NP_001035265.1

Gene Ontology
Bibliography

Related articles in PubMed

SLC26A3 (DRA) prevents TNF-alpha-induced barrier dysfunction and dextran sulfate sodium-induced acute colitis.
Ding X, Li D, Li M, Wang H, He Q, Wang Y, Yu H, Tian D, Yu Q
Laboratory investigation; a journal of technical methods and pathology(2018 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In intestinal cells, TNF activates NF-kappaB, which reduces expression of the Cl(-) / HCO3(-) exchanger SLC26A3, via direct binding to the promoter region.
Title: Activation of Nuclear Factor-?B by Tumor Necrosis Factor in Intestinal Epithelial Cells and Mouse Intestinal Epithelia Reduces Expression of the Chloride Transporter SLC26A3.

Genetic variations of the SLC26A3 rs2108225 is associated with enhance the risk of ulcerative colitis.
Title: [Association of solute-linked carrier family 26 member A3 gene polymorphisms with ulcerative colitis among Chinese patients].

Expression of NHE3 and DRA was reduced with high tacrolimus levels and impaired renal function after intestinal transplantation.
Title: After Intestinal Transplantation Kidney Function Is Impaired by Downregulation of Epithelial Ion Transporters in the Ileum.

We report the first Tunisian case of SLC26A3 gene mutation in congenital chloride diarrhea. Our patient was homozygous for G187X mutation. Both parents were heterozygous for the same mutation.
Title: SLC26A3 gene mutations in Tunisian patients with congenital chloride diarrhea.

A variety of mutations in SLC26A3 are responsible for CCD. A total of 55 mutations in SLC26A3 have been reported
Title: Japanese neonate with congenital chloride diarrhea caused by SLC26A3 mutation.

The following SLC26A3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC26A3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26676	NM_000111.3 Latest version!	Homo sapiens solute carrier family 26 member 3 (SLC26A3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu26676	XM_011515867.2 Latest version!	Homo sapiens solute carrier family 26 member 3 (SLC26A3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
View Old Accession Versions >>
OHu26676	NM_000111.2	Homo sapiens solute carrier family 26 member 3 (SLC26A3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu26676	XM_011515867.1	Homo sapiens solute carrier family 26 (anion exchanger), member 3 (SLC26A3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLC26A3 ( NM_000111.2 ) cDNA ORF clone, Homo sapiens(Human) -> NP_000102.1 Homo sapiens solute carrier family 26 member 3 (SLC26A3), mRNA.

Price & Availability↑

CloneID	OHu26676
Clone ID Related Accession (Same CDS sequence)	NM_000111.2 , NM_000111.3 , XM_011515867.2 , XM_011515867.1
Accession Version	NM_000111.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2295bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-10
Organism	Homo sapiens(human)
Product	chloride anion exchanger
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP262081.1, BC025671.1 and AC002467.1. This sequence is a reference standard in the RefSeqGene project. On Apr 1, 2008 this sequence version replaced NM_000111.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC025671.1, L02785.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGATTGAAC CCTTTGGGAA TCAGTATATT GTGGCCAGGC CAGTGTATTC TACAAATGCT 
TTTGAGGAAA ATCATAAAAA GACAGGAAGA CATCATAAGA CATTTCTGGA TCATCTCAAA 
GTGTGTTGTA GCTGTTCCCC ACAAAAGGCC AAGAGAATTG TCCTCTCTTT GTTCCCCATA 
GCATCTTGGT TGCCAGCATA CCGGCTTAAA GAATGGTTGC TCAGTGATAT TGTTTCTGGT 
ATCAGCACAG GGATTGTGGC CGTACTACAA GGTTTAGCAT TTGCTCTGCT GGTCGACATT 
CCCCCAGTCT ATGGGTTGTA TGCATCCTTT TTCCCAGCCA TAATCTACCT TTTCTTCGGC 
ACTTCCAGAC ACATATCCGT GGGTCCGTTT CCGATTCTGA GTATGATGGT GGGACTAGCA 
GTTTCAGGAG CAGTTTCAAA AGCAGTCCCA GATCGCAATG CAACTACTTT GGGATTGCCT 
AACAACTCGA ATAATTCTTC ACTACTGGAT GACGAGAGGG TGAGGGTGGC GGCGGCGGCA 
TCAGTCACAG TGCTTTCTGG AATCATCCAG TTGGCTTTTG GGATTCTGCG GATTGGATTT 
GTAGTGATAT ACCTGTCTGA GTCCCTCATC AGTGGCTTCA CTACTGCTGC TGCTGTTCAT 
GTTTTGGTTT CCCAACTCAA ATTCATTTTT CAGTTGACAG TCCCGTCACA CACTGATCCA 
GTTTCAATTT TCAAAGTACT ATACTCTGTA TTCTCACAAA TAGAGAAGAC TAATATTGCA 
GACCTGGTGA CAGCTCTGAT TGTCCTTTTG GTTGTATCCA TTGTTAAAGA AATAAATCAG 
CGCTTCAAAG ACAAACTTCC AGTGCCCATT CCAATCGAAT TCATTATGAC CGTGATTGCA 
GCAGGTGTAT CCTACGGCTG TGACTTTAAA AACAGGTTTA AAGTGGCTGT GGTTGGGGAC 
ATGAATCCTG GATTTCAGCC CCCTATTACA CCTGACGTGG AGACTTTCCA AAACACCGTA 
GGAGATTGCT TCGGCATCGC AATGGTTGCA TTTGCAGTGG CCTTTTCAGT TGCCAGCGTC 
TATTCCCTCA AATACGATTA TCCACTTGAT GGCAATCAGG AGTTAATAGC CTTGGGACTG 
GGTAACATAG TCTGTGGAGT ATTCAGAGGA TTTGCTGGGA GTACTGCCCT CTCCAGATCA 
GCAGTTCAGG AGAGCACAGG AGGCAAAACA CAGATTGCTG GGCTTATTGG TGCCATCATC 
GTGCTGATTG TCGTTCTAGC CATTGGATTT CTCCTGGCGC CTCTACAAAA GTCCGTCCTG 
GCAGCTTTAG CATTGGGAAA CTTAAAGGGA ATGCTGATGC AGTTTGCTGA AATAGGCAGA 
TTGTGGCGAA AGGACAAATA TGATTGTTTA ATTTGGATCA TGACCTTCAT CTTCACCATT 
GTCCTGGGAC TCGGGTTAGG CCTGGCAGCT AGTGTGGCAT TTCAACTGCT AACCATCGTG 
TTCAGGACCC AATTTCCAAA ATGCAGCACG CTGGCTAATA TTGGAAGAAC CAACATCTAT 
AAGAATAAAA AAGATTATTA TGATATGTAT GAGCCAGAAG GAGTGAAAAT TTTCAGATGT 
CCATCTCCTA TCTACTTTGC AAACATTGGT TTCTTTAGGC GGAAACTTAT CGATGCTGTT 
GGCTTTAGTC CACTTCGAAT TCTACGCAAG CGCAACAAAG CTTTGAGGAA AATCCGAAAA 
CTGCAGAAGC AAGGCTTGCT ACAAGTGACA CCAAAAGGAT TTATATGTAC TGTTGACACC 
ATAAAAGATT CTGACGAAGA GCTGGACAAC AATCAGATAG AAGTACTGGA CCAGCCAATC 
AATACCACAG ACCTGCCTTT CCACATTGAC TGGAATGATG ATCTTCCTCT CAACATTGAG 
GTCCCCAAAA TCAGCCTCCA CAGCCTCATT CTTGACTTTT CAGCAGTGTC CTTTCTTGAT 
GTTTCTTCAG TGAGGGGCCT TAAATCGATT TTGCAAGAAT TTATCAGGAT CAAGGTAGAT 
GTGTATATCG TTGGAACTGA TGATGACTTC ATTGAGAAGC TTAACCGGTA TGAATTTTTT 
GATGGTGAAG TGAAAAGCTC AATATTTTTC TTAACAATCC ATGATGCTGT TTTGCATATT 
TTGATGAAGA AAGATTACAG TACTTCAAAG TTTAATCCCA GTCAGGAAAA AGATGGAAAA 
ATTGATTTTA CCATAAATAC AAATGGAGGA TTACGTAATC GGGTATATGA GGTGCCAGTT 
GAAACAAAAT TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000102.1
CDS	212..2506
Translation	MIEPFGNQYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGCDFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFRRKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDTIKDSDEELDNNQIEVLDQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVLHILMKKDYSTSKFNPSQEKDGKIDFTINTNGGLRNRVYEVPVETKF

Target ORF information:

RefSeq Version	NM_000111.2
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 26 member 3 (SLC26A3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000111.2

ORF Insert Sequence:

ATGATTGAAC CCTTTGGGAA TCAGTATATT GTGGCCAGGC CAGTGTATTC TACAAATGCT 
TTTGAGGAAA ATCATAAAAA GACAGGAAGA CATCATAAGA CATTTCTGGA TCATCTCAAA 
GTGTGTTGTA GCTGTTCCCC ACAAAAGGCC AAGAGAATTG TCCTCTCTTT GTTCCCCATA 
GCATCTTGGT TGCCAGCATA CCGGCTTAAA GAATGGTTGC TCAGTGATAT TGTTTCTGGT 
ATCAGCACAG GGATTGTGGC CGTACTACAA GGTTTAGCAT TTGCTCTGCT GGTCGACATT 
CCCCCAGTCT ATGGGTTGTA TGCATCCTTT TTCCCAGCCA TAATCTACCT TTTCTTCGGC 
ACTTCCAGAC ACATATCCGT GGGTCCGTTT CCGATTCTGA GTATGATGGT GGGACTAGCA 
GTTTCAGGAG CAGTTTCAAA AGCAGTCCCA GATCGCAATG CAACTACTTT GGGATTGCCT 
AACAACTCGA ATAATTCTTC ACTACTGGAT GACGAGAGGG TGAGGGTGGC GGCGGCGGCA 
TCAGTCACAG TGCTTTCTGG AATCATCCAG TTGGCTTTTG GGATTCTGCG GATTGGATTT 
GTAGTGATAT ACCTGTCTGA GTCCCTCATC AGTGGCTTCA CTACTGCTGC TGCTGTTCAT 
GTTTTGGTTT CCCAACTCAA ATTCATTTTT CAGTTGACAG TCCCGTCACA CACTGATCCA 
GTTTCAATTT TCAAAGTACT ATACTCTGTA TTCTCACAAA TAGAGAAGAC TAATATTGCA 
GACCTGGTGA CAGCTCTGAT TGTCCTTTTG GTTGTATCCA TTGTTAAAGA AATAAATCAG 
CGCTTCAAAG ACAAACTTCC AGTGCCCATT CCAATCGAAT TCATTATGAC CGTGATTGCA 
GCAGGTGTAT CCTACGGCTG TGACTTTAAA AACAGGTTTA AAGTGGCTGT GGTTGGGGAC 
ATGAATCCTG GATTTCAGCC CCCTATTACA CCTGACGTGG AGACTTTCCA AAACACCGTA 
GGAGATTGCT TCGGCATCGC AATGGTTGCA TTTGCAGTGG CCTTTTCAGT TGCCAGCGTC 
TATTCCCTCA AATACGATTA TCCACTTGAT GGCAATCAGG AGTTAATAGC CTTGGGACTG 
GGTAACATAG TCTGTGGAGT ATTCAGAGGA TTTGCTGGGA GTACTGCCCT CTCCAGATCA 
GCAGTTCAGG AGAGCACAGG AGGCAAAACA CAGATTGCTG GGCTTATTGG TGCCATCATC 
GTGCTGATTG TCGTTCTAGC CATTGGATTT CTCCTGGCGC CTCTACAAAA GTCCGTCCTG 
GCAGCTTTAG CATTGGGAAA CTTAAAGGGA ATGCTGATGC AGTTTGCTGA AATAGGCAGA 
TTGTGGCGAA AGGACAAATA TGATTGTTTA ATTTGGATCA TGACCTTCAT CTTCACCATT 
GTCCTGGGAC TCGGGTTAGG CCTGGCAGCT AGTGTGGCAT TTCAACTGCT AACCATCGTG 
TTCAGGACCC AATTTCCAAA ATGCAGCACG CTGGCTAATA TTGGAAGAAC CAACATCTAT 
AAGAATAAAA AAGATTATTA TGATATGTAT GAGCCAGAAG GAGTGAAAAT TTTCAGATGT 
CCATCTCCTA TCTACTTTGC AAACATTGGT TTCTTTAGGC GGAAACTTAT CGATGCTGTT 
GGCTTTAGTC CACTTCGAAT TCTACGCAAG CGCAACAAAG CTTTGAGGAA AATCCGAAAA 
CTGCAGAAGC AAGGCTTGCT ACAAGTGACA CCAAAAGGAT TTATATGTAC TGTTGACACC 
ATAAAAGATT CTGACGAAGA GCTGGACAAC AATCAGATAG AAGTACTGGA CCAGCCAATC 
AATACCACAG ACCTGCCTTT CCACATTGAC TGGAATGATG ATCTTCCTCT CAACATTGAG 
GTCCCCAAAA TCAGCCTCCA CAGCCTCATT CTTGACTTTT CAGCAGTGTC CTTTCTTGAT 
GTTTCTTCAG TGAGGGGCCT TAAATCGATT TTGCAAGAAT TTATCAGGAT CAAGGTAGAT 
GTGTATATCG TTGGAACTGA TGATGACTTC ATTGAGAAGC TTAACCGGTA TGAATTTTTT 
GATGGTGAAG TGAAAAGCTC AATATTTTTC TTAACAATCC ATGATGCTGT TTTGCATATT 
TTGATGAAGA AAGATTACAG TACTTCAAAG TTTAATCCCA GTCAGGAAAA AGATGGAAAA 
ATTGATTTTA CCATAAATAC AAATGGAGGA TTACGTAATC GGGTATATGA GGTGCCAGTT 
GAAACAAAAT TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC26A3 ( NM_000111.3 ) cDNA ORF clone, Homo sapiens(Human) -> NP_000102.1 Homo sapiens solute carrier family 26 member 3 (SLC26A3), mRNA.

Price & Availability↑

CloneID	OHu26676
Clone ID Related Accession (Same CDS sequence)	NM_000111.2 , NM_000111.3 , XM_011515867.2 , XM_011515867.1
Accession Version	NM_000111.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2295bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Homo sapiens(human)
Product	chloride anion exchanger
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP262081.1, BC025671.1 and AC002467.1. On Aug 31, 2019 this sequence version replaced NM_000111.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L02785.1, BC025671.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGATTGAAC CCTTTGGGAA TCAGTATATT GTGGCCAGGC CAGTGTATTC TACAAATGCT 
TTTGAGGAAA ATCATAAAAA GACAGGAAGA CATCATAAGA CATTTCTGGA TCATCTCAAA 
GTGTGTTGTA GCTGTTCCCC ACAAAAGGCC AAGAGAATTG TCCTCTCTTT GTTCCCCATA 
GCATCTTGGT TGCCAGCATA CCGGCTTAAA GAATGGTTGC TCAGTGATAT TGTTTCTGGT 
ATCAGCACAG GGATTGTGGC CGTACTACAA GGTTTAGCAT TTGCTCTGCT GGTCGACATT 
CCCCCAGTCT ATGGGTTGTA TGCATCCTTT TTCCCAGCCA TAATCTACCT TTTCTTCGGC 
ACTTCCAGAC ACATATCCGT GGGTCCGTTT CCGATTCTGA GTATGATGGT GGGACTAGCA 
GTTTCAGGAG CAGTTTCAAA AGCAGTCCCA GATCGCAATG CAACTACTTT GGGATTGCCT 
AACAACTCGA ATAATTCTTC ACTACTGGAT GACGAGAGGG TGAGGGTGGC GGCGGCGGCA 
TCAGTCACAG TGCTTTCTGG AATCATCCAG TTGGCTTTTG GGATTCTGCG GATTGGATTT 
GTAGTGATAT ACCTGTCTGA GTCCCTCATC AGTGGCTTCA CTACTGCTGC TGCTGTTCAT 
GTTTTGGTTT CCCAACTCAA ATTCATTTTT CAGTTGACAG TCCCGTCACA CACTGATCCA 
GTTTCAATTT TCAAAGTACT ATACTCTGTA TTCTCACAAA TAGAGAAGAC TAATATTGCA 
GACCTGGTGA CAGCTCTGAT TGTCCTTTTG GTTGTATCCA TTGTTAAAGA AATAAATCAG 
CGCTTCAAAG ACAAACTTCC AGTGCCCATT CCAATCGAAT TCATTATGAC CGTGATTGCA 
GCAGGTGTAT CCTACGGCTG TGACTTTAAA AACAGGTTTA AAGTGGCTGT GGTTGGGGAC 
ATGAATCCTG GATTTCAGCC CCCTATTACA CCTGACGTGG AGACTTTCCA AAACACCGTA 
GGAGATTGCT TCGGCATCGC AATGGTTGCA TTTGCAGTGG CCTTTTCAGT TGCCAGCGTC 
TATTCCCTCA AATACGATTA TCCACTTGAT GGCAATCAGG AGTTAATAGC CTTGGGACTG 
GGTAACATAG TCTGTGGAGT ATTCAGAGGA TTTGCTGGGA GTACTGCCCT CTCCAGATCA 
GCAGTTCAGG AGAGCACAGG AGGCAAAACA CAGATTGCTG GGCTTATTGG TGCCATCATC 
GTGCTGATTG TCGTTCTAGC CATTGGATTT CTCCTGGCGC CTCTACAAAA GTCCGTCCTG 
GCAGCTTTAG CATTGGGAAA CTTAAAGGGA ATGCTGATGC AGTTTGCTGA AATAGGCAGA 
TTGTGGCGAA AGGACAAATA TGATTGTTTA ATTTGGATCA TGACCTTCAT CTTCACCATT 
GTCCTGGGAC TCGGGTTAGG CCTGGCAGCT AGTGTGGCAT TTCAACTGCT AACCATCGTG 
TTCAGGACCC AATTTCCAAA ATGCAGCACG CTGGCTAATA TTGGAAGAAC CAACATCTAT 
AAGAATAAAA AAGATTATTA TGATATGTAT GAGCCAGAAG GAGTGAAAAT TTTCAGATGT 
CCATCTCCTA TCTACTTTGC AAACATTGGT TTCTTTAGGC GGAAACTTAT CGATGCTGTT 
GGCTTTAGTC CACTTCGAAT TCTACGCAAG CGCAACAAAG CTTTGAGGAA AATCCGAAAA 
CTGCAGAAGC AAGGCTTGCT ACAAGTGACA CCAAAAGGAT TTATATGTAC TGTTGACACC 
ATAAAAGATT CTGACGAAGA GCTGGACAAC AATCAGATAG AAGTACTGGA CCAGCCAATC 
AATACCACAG ACCTGCCTTT CCACATTGAC TGGAATGATG ATCTTCCTCT CAACATTGAG 
GTCCCCAAAA TCAGCCTCCA CAGCCTCATT CTTGACTTTT CAGCAGTGTC CTTTCTTGAT 
GTTTCTTCAG TGAGGGGCCT TAAATCGATT TTGCAAGAAT TTATCAGGAT CAAGGTAGAT 
GTGTATATCG TTGGAACTGA TGATGACTTC ATTGAGAAGC TTAACCGGTA TGAATTTTTT 
GATGGTGAAG TGAAAAGCTC AATATTTTTC TTAACAATCC ATGATGCTGT TTTGCATATT 
TTGATGAAGA AAGATTACAG TACTTCAAAG TTTAATCCCA GTCAGGAAAA AGATGGAAAA 
ATTGATTTTA CCATAAATAC AAATGGAGGA TTACGTAATC GGGTATATGA GGTGCCAGTT 
GAAACAAAAT TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000102.1
CDS	202..2496
Translation	MIEPFGNQYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGCDFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFRRKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDTIKDSDEELDNNQIEVLDQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVLHILMKKDYSTSKFNPSQEKDGKIDFTINTNGGLRNRVYEVPVETKF

Target ORF information:

RefSeq Version	NM_000111.3
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 26 member 3 (SLC26A3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000111.3

ORF Insert Sequence:

ATGATTGAAC CCTTTGGGAA TCAGTATATT GTGGCCAGGC CAGTGTATTC TACAAATGCT 
TTTGAGGAAA ATCATAAAAA GACAGGAAGA CATCATAAGA CATTTCTGGA TCATCTCAAA 
GTGTGTTGTA GCTGTTCCCC ACAAAAGGCC AAGAGAATTG TCCTCTCTTT GTTCCCCATA 
GCATCTTGGT TGCCAGCATA CCGGCTTAAA GAATGGTTGC TCAGTGATAT TGTTTCTGGT 
ATCAGCACAG GGATTGTGGC CGTACTACAA GGTTTAGCAT TTGCTCTGCT GGTCGACATT 
CCCCCAGTCT ATGGGTTGTA TGCATCCTTT TTCCCAGCCA TAATCTACCT TTTCTTCGGC 
ACTTCCAGAC ACATATCCGT GGGTCCGTTT CCGATTCTGA GTATGATGGT GGGACTAGCA 
GTTTCAGGAG CAGTTTCAAA AGCAGTCCCA GATCGCAATG CAACTACTTT GGGATTGCCT 
AACAACTCGA ATAATTCTTC ACTACTGGAT GACGAGAGGG TGAGGGTGGC GGCGGCGGCA 
TCAGTCACAG TGCTTTCTGG AATCATCCAG TTGGCTTTTG GGATTCTGCG GATTGGATTT 
GTAGTGATAT ACCTGTCTGA GTCCCTCATC AGTGGCTTCA CTACTGCTGC TGCTGTTCAT 
GTTTTGGTTT CCCAACTCAA ATTCATTTTT CAGTTGACAG TCCCGTCACA CACTGATCCA 
GTTTCAATTT TCAAAGTACT ATACTCTGTA TTCTCACAAA TAGAGAAGAC TAATATTGCA 
GACCTGGTGA CAGCTCTGAT TGTCCTTTTG GTTGTATCCA TTGTTAAAGA AATAAATCAG 
CGCTTCAAAG ACAAACTTCC AGTGCCCATT CCAATCGAAT TCATTATGAC CGTGATTGCA 
GCAGGTGTAT CCTACGGCTG TGACTTTAAA AACAGGTTTA AAGTGGCTGT GGTTGGGGAC 
ATGAATCCTG GATTTCAGCC CCCTATTACA CCTGACGTGG AGACTTTCCA AAACACCGTA 
GGAGATTGCT TCGGCATCGC AATGGTTGCA TTTGCAGTGG CCTTTTCAGT TGCCAGCGTC 
TATTCCCTCA AATACGATTA TCCACTTGAT GGCAATCAGG AGTTAATAGC CTTGGGACTG 
GGTAACATAG TCTGTGGAGT ATTCAGAGGA TTTGCTGGGA GTACTGCCCT CTCCAGATCA 
GCAGTTCAGG AGAGCACAGG AGGCAAAACA CAGATTGCTG GGCTTATTGG TGCCATCATC 
GTGCTGATTG TCGTTCTAGC CATTGGATTT CTCCTGGCGC CTCTACAAAA GTCCGTCCTG 
GCAGCTTTAG CATTGGGAAA CTTAAAGGGA ATGCTGATGC AGTTTGCTGA AATAGGCAGA 
TTGTGGCGAA AGGACAAATA TGATTGTTTA ATTTGGATCA TGACCTTCAT CTTCACCATT 
GTCCTGGGAC TCGGGTTAGG CCTGGCAGCT AGTGTGGCAT TTCAACTGCT AACCATCGTG 
TTCAGGACCC AATTTCCAAA ATGCAGCACG CTGGCTAATA TTGGAAGAAC CAACATCTAT 
AAGAATAAAA AAGATTATTA TGATATGTAT GAGCCAGAAG GAGTGAAAAT TTTCAGATGT 
CCATCTCCTA TCTACTTTGC AAACATTGGT TTCTTTAGGC GGAAACTTAT CGATGCTGTT 
GGCTTTAGTC CACTTCGAAT TCTACGCAAG CGCAACAAAG CTTTGAGGAA AATCCGAAAA 
CTGCAGAAGC AAGGCTTGCT ACAAGTGACA CCAAAAGGAT TTATATGTAC TGTTGACACC 
ATAAAAGATT CTGACGAAGA GCTGGACAAC AATCAGATAG AAGTACTGGA CCAGCCAATC 
AATACCACAG ACCTGCCTTT CCACATTGAC TGGAATGATG ATCTTCCTCT CAACATTGAG 
GTCCCCAAAA TCAGCCTCCA CAGCCTCATT CTTGACTTTT CAGCAGTGTC CTTTCTTGAT 
GTTTCTTCAG TGAGGGGCCT TAAATCGATT TTGCAAGAAT TTATCAGGAT CAAGGTAGAT 
GTGTATATCG TTGGAACTGA TGATGACTTC ATTGAGAAGC TTAACCGGTA TGAATTTTTT 
GATGGTGAAG TGAAAAGCTC AATATTTTTC TTAACAATCC ATGATGCTGT TTTGCATATT 
TTGATGAAGA AAGATTACAG TACTTCAAAG TTTAATCCCA GTCAGGAAAA AGATGGAAAA 
ATTGATTTTA CCATAAATAC AAATGGAGGA TTACGTAATC GGGTATATGA GGTGCCAGTT 
GAAACAAAAT TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC26A3 ( XM_011515867.2 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011514169.1 Homo sapiens solute carrier family 26 member 3 (SLC26A3), transcript variant X1, mRNA.

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CloneID	OHu26676
Clone ID Related Accession (Same CDS sequence)	NM_000111.2 , NM_000111.3 , XM_011515867.2 , XM_011515867.1
Accession Version	XM_011515867.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2295bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	chloride anion exchanger isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011515867.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTGAAC CCTTTGGGAA TCAGTATATT GTGGCCAGGC CAGTGTATTC TACAAATGCT 
TTTGAGGAAA ATCATAAAAA GACAGGAAGA CATCATAAGA CATTTCTGGA TCATCTCAAA 
GTGTGTTGTA GCTGTTCCCC ACAAAAGGCC AAGAGAATTG TCCTCTCTTT GTTCCCCATA 
GCATCTTGGT TGCCAGCATA CCGGCTTAAA GAATGGTTGC TCAGTGATAT TGTTTCTGGT 
ATCAGCACAG GGATTGTGGC CGTACTACAA GGTTTAGCAT TTGCTCTGCT GGTCGACATT 
CCCCCAGTCT ATGGGTTGTA TGCATCCTTT TTCCCAGCCA TAATCTACCT TTTCTTCGGC 
ACTTCCAGAC ACATATCCGT GGGTCCGTTT CCGATTCTGA GTATGATGGT GGGACTAGCA 
GTTTCAGGAG CAGTTTCAAA AGCAGTCCCA GATCGCAATG CAACTACTTT GGGATTGCCT 
AACAACTCGA ATAATTCTTC ACTACTGGAT GACGAGAGGG TGAGGGTGGC GGCGGCGGCA 
TCAGTCACAG TGCTTTCTGG AATCATCCAG TTGGCTTTTG GGATTCTGCG GATTGGATTT 
GTAGTGATAT ACCTGTCTGA GTCCCTCATC AGTGGCTTCA CTACTGCTGC TGCTGTTCAT 
GTTTTGGTTT CCCAACTCAA ATTCATTTTT CAGTTGACAG TCCCGTCACA CACTGATCCA 
GTTTCAATTT TCAAAGTACT ATACTCTGTA TTCTCACAAA TAGAGAAGAC TAATATTGCA 
GACCTGGTGA CAGCTCTGAT TGTCCTTTTG GTTGTATCCA TTGTTAAAGA AATAAATCAG 
CGCTTCAAAG ACAAACTTCC AGTGCCCATT CCAATCGAAT TCATTATGAC CGTGATTGCA 
GCAGGTGTAT CCTACGGCTG TGACTTTAAA AACAGGTTTA AAGTGGCTGT GGTTGGGGAC 
ATGAATCCTG GATTTCAGCC CCCTATTACA CCTGACGTGG AGACTTTCCA AAACACCGTA 
GGAGATTGCT TCGGCATCGC AATGGTTGCA TTTGCAGTGG CCTTTTCAGT TGCCAGCGTC 
TATTCCCTCA AATACGATTA TCCACTTGAT GGCAATCAGG AGTTAATAGC CTTGGGACTG 
GGTAACATAG TCTGTGGAGT ATTCAGAGGA TTTGCTGGGA GTACTGCCCT CTCCAGATCA 
GCAGTTCAGG AGAGCACAGG AGGCAAAACA CAGATTGCTG GGCTTATTGG TGCCATCATC 
GTGCTGATTG TCGTTCTAGC CATTGGATTT CTCCTGGCGC CTCTACAAAA GTCCGTCCTG 
GCAGCTTTAG CATTGGGAAA CTTAAAGGGA ATGCTGATGC AGTTTGCTGA AATAGGCAGA 
TTGTGGCGAA AGGACAAATA TGATTGTTTA ATTTGGATCA TGACCTTCAT CTTCACCATT 
GTCCTGGGAC TCGGGTTAGG CCTGGCAGCT AGTGTGGCAT TTCAACTGCT AACCATCGTG 
TTCAGGACCC AATTTCCAAA ATGCAGCACG CTGGCTAATA TTGGAAGAAC CAACATCTAT 
AAGAATAAAA AAGATTATTA TGATATGTAT GAGCCAGAAG GAGTGAAAAT TTTCAGATGT 
CCATCTCCTA TCTACTTTGC AAACATTGGT TTCTTTAGGC GGAAACTTAT CGATGCTGTT 
GGCTTTAGTC CACTTCGAAT TCTACGCAAG CGCAACAAAG CTTTGAGGAA AATCCGAAAA 
CTGCAGAAGC AAGGCTTGCT ACAAGTGACA CCAAAAGGAT TTATATGTAC TGTTGACACC 
ATAAAAGATT CTGACGAAGA GCTGGACAAC AATCAGATAG AAGTACTGGA CCAGCCAATC 
AATACCACAG ACCTGCCTTT CCACATTGAC TGGAATGATG ATCTTCCTCT CAACATTGAG 
GTCCCCAAAA TCAGCCTCCA CAGCCTCATT CTTGACTTTT CAGCAGTGTC CTTTCTTGAT 
GTTTCTTCAG TGAGGGGCCT TAAATCGATT TTGCAAGAAT TTATCAGGAT CAAGGTAGAT 
GTGTATATCG TTGGAACTGA TGATGACTTC ATTGAGAAGC TTAACCGGTA TGAATTTTTT 
GATGGTGAAG TGAAAAGCTC AATATTTTTC TTAACAATCC ATGATGCTGT TTTGCATATT 
TTGATGAAGA AAGATTACAG TACTTCAAAG TTTAATCCCA GTCAGGAAAA AGATGGAAAA 
ATTGATTTTA CCATAAATAC AAATGGAGGA TTACGTAATC GGGTATATGA GGTGCCAGTT 
GAAACAAAAT TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011514169.1
CDS	193..2487
Translation	MIEPFGNQYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGCDFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFRRKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDTIKDSDEELDNNQIEVLDQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVLHILMKKDYSTSKFNPSQEKDGKIDFTINTNGGLRNRVYEVPVETKF

Target ORF information:

RefSeq Version	XM_011515867.2
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 26 member 3 (SLC26A3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011515867.2

ORF Insert Sequence:

ATGATTGAAC CCTTTGGGAA TCAGTATATT GTGGCCAGGC CAGTGTATTC TACAAATGCT 
TTTGAGGAAA ATCATAAAAA GACAGGAAGA CATCATAAGA CATTTCTGGA TCATCTCAAA 
GTGTGTTGTA GCTGTTCCCC ACAAAAGGCC AAGAGAATTG TCCTCTCTTT GTTCCCCATA 
GCATCTTGGT TGCCAGCATA CCGGCTTAAA GAATGGTTGC TCAGTGATAT TGTTTCTGGT 
ATCAGCACAG GGATTGTGGC CGTACTACAA GGTTTAGCAT TTGCTCTGCT GGTCGACATT 
CCCCCAGTCT ATGGGTTGTA TGCATCCTTT TTCCCAGCCA TAATCTACCT TTTCTTCGGC 
ACTTCCAGAC ACATATCCGT GGGTCCGTTT CCGATTCTGA GTATGATGGT GGGACTAGCA 
GTTTCAGGAG CAGTTTCAAA AGCAGTCCCA GATCGCAATG CAACTACTTT GGGATTGCCT 
AACAACTCGA ATAATTCTTC ACTACTGGAT GACGAGAGGG TGAGGGTGGC GGCGGCGGCA 
TCAGTCACAG TGCTTTCTGG AATCATCCAG TTGGCTTTTG GGATTCTGCG GATTGGATTT 
GTAGTGATAT ACCTGTCTGA GTCCCTCATC AGTGGCTTCA CTACTGCTGC TGCTGTTCAT 
GTTTTGGTTT CCCAACTCAA ATTCATTTTT CAGTTGACAG TCCCGTCACA CACTGATCCA 
GTTTCAATTT TCAAAGTACT ATACTCTGTA TTCTCACAAA TAGAGAAGAC TAATATTGCA 
GACCTGGTGA CAGCTCTGAT TGTCCTTTTG GTTGTATCCA TTGTTAAAGA AATAAATCAG 
CGCTTCAAAG ACAAACTTCC AGTGCCCATT CCAATCGAAT TCATTATGAC CGTGATTGCA 
GCAGGTGTAT CCTACGGCTG TGACTTTAAA AACAGGTTTA AAGTGGCTGT GGTTGGGGAC 
ATGAATCCTG GATTTCAGCC CCCTATTACA CCTGACGTGG AGACTTTCCA AAACACCGTA 
GGAGATTGCT TCGGCATCGC AATGGTTGCA TTTGCAGTGG CCTTTTCAGT TGCCAGCGTC 
TATTCCCTCA AATACGATTA TCCACTTGAT GGCAATCAGG AGTTAATAGC CTTGGGACTG 
GGTAACATAG TCTGTGGAGT ATTCAGAGGA TTTGCTGGGA GTACTGCCCT CTCCAGATCA 
GCAGTTCAGG AGAGCACAGG AGGCAAAACA CAGATTGCTG GGCTTATTGG TGCCATCATC 
GTGCTGATTG TCGTTCTAGC CATTGGATTT CTCCTGGCGC CTCTACAAAA GTCCGTCCTG 
GCAGCTTTAG CATTGGGAAA CTTAAAGGGA ATGCTGATGC AGTTTGCTGA AATAGGCAGA 
TTGTGGCGAA AGGACAAATA TGATTGTTTA ATTTGGATCA TGACCTTCAT CTTCACCATT 
GTCCTGGGAC TCGGGTTAGG CCTGGCAGCT AGTGTGGCAT TTCAACTGCT AACCATCGTG 
TTCAGGACCC AATTTCCAAA ATGCAGCACG CTGGCTAATA TTGGAAGAAC CAACATCTAT 
AAGAATAAAA AAGATTATTA TGATATGTAT GAGCCAGAAG GAGTGAAAAT TTTCAGATGT 
CCATCTCCTA TCTACTTTGC AAACATTGGT TTCTTTAGGC GGAAACTTAT CGATGCTGTT 
GGCTTTAGTC CACTTCGAAT TCTACGCAAG CGCAACAAAG CTTTGAGGAA AATCCGAAAA 
CTGCAGAAGC AAGGCTTGCT ACAAGTGACA CCAAAAGGAT TTATATGTAC TGTTGACACC 
ATAAAAGATT CTGACGAAGA GCTGGACAAC AATCAGATAG AAGTACTGGA CCAGCCAATC 
AATACCACAG ACCTGCCTTT CCACATTGAC TGGAATGATG ATCTTCCTCT CAACATTGAG 
GTCCCCAAAA TCAGCCTCCA CAGCCTCATT CTTGACTTTT CAGCAGTGTC CTTTCTTGAT 
GTTTCTTCAG TGAGGGGCCT TAAATCGATT TTGCAAGAAT TTATCAGGAT CAAGGTAGAT 
GTGTATATCG TTGGAACTGA TGATGACTTC ATTGAGAAGC TTAACCGGTA TGAATTTTTT 
GATGGTGAAG TGAAAAGCTC AATATTTTTC TTAACAATCC ATGATGCTGT TTTGCATATT 
TTGATGAAGA AAGATTACAG TACTTCAAAG TTTAATCCCA GTCAGGAAAA AGATGGAAAA 
ATTGATTTTA CCATAAATAC AAATGGAGGA TTACGTAATC GGGTATATGA GGTGCCAGTT 
GAAACAAAAT TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC26A3 ( XM_011515867.1 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011514169.1 Homo sapiens solute carrier family 26 (anion exchanger), member 3 (SLC26A3), transcript variant X1, mRNA.

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CloneID	OHu26676
Clone ID Related Accession (Same CDS sequence)	NM_000111.2 , NM_000111.3 , XM_011515867.2 , XM_011515867.1
Accession Version	XM_011515867.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2295bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	chloride anion exchanger isoform X1
Comment

ATGATTGAAC CCTTTGGGAA TCAGTATATT GTGGCCAGGC CAGTGTATTC TACAAATGCT 
TTTGAGGAAA ATCATAAAAA GACAGGAAGA CATCATAAGA CATTTCTGGA TCATCTCAAA 
GTGTGTTGTA GCTGTTCCCC ACAAAAGGCC AAGAGAATTG TCCTCTCTTT GTTCCCCATA 
GCATCTTGGT TGCCAGCATA CCGGCTTAAA GAATGGTTGC TCAGTGATAT TGTTTCTGGT 
ATCAGCACAG GGATTGTGGC CGTACTACAA GGTTTAGCAT TTGCTCTGCT GGTCGACATT 
CCCCCAGTCT ATGGGTTGTA TGCATCCTTT TTCCCAGCCA TAATCTACCT TTTCTTCGGC 
ACTTCCAGAC ACATATCCGT GGGTCCGTTT CCGATTCTGA GTATGATGGT GGGACTAGCA 
GTTTCAGGAG CAGTTTCAAA AGCAGTCCCA GATCGCAATG CAACTACTTT GGGATTGCCT 
AACAACTCGA ATAATTCTTC ACTACTGGAT GACGAGAGGG TGAGGGTGGC GGCGGCGGCA 
TCAGTCACAG TGCTTTCTGG AATCATCCAG TTGGCTTTTG GGATTCTGCG GATTGGATTT 
GTAGTGATAT ACCTGTCTGA GTCCCTCATC AGTGGCTTCA CTACTGCTGC TGCTGTTCAT 
GTTTTGGTTT CCCAACTCAA ATTCATTTTT CAGTTGACAG TCCCGTCACA CACTGATCCA 
GTTTCAATTT TCAAAGTACT ATACTCTGTA TTCTCACAAA TAGAGAAGAC TAATATTGCA 
GACCTGGTGA CAGCTCTGAT TGTCCTTTTG GTTGTATCCA TTGTTAAAGA AATAAATCAG 
CGCTTCAAAG ACAAACTTCC AGTGCCCATT CCAATCGAAT TCATTATGAC CGTGATTGCA 
GCAGGTGTAT CCTACGGCTG TGACTTTAAA AACAGGTTTA AAGTGGCTGT GGTTGGGGAC 
ATGAATCCTG GATTTCAGCC CCCTATTACA CCTGACGTGG AGACTTTCCA AAACACCGTA 
GGAGATTGCT TCGGCATCGC AATGGTTGCA TTTGCAGTGG CCTTTTCAGT TGCCAGCGTC 
TATTCCCTCA AATACGATTA TCCACTTGAT GGCAATCAGG AGTTAATAGC CTTGGGACTG 
GGTAACATAG TCTGTGGAGT ATTCAGAGGA TTTGCTGGGA GTACTGCCCT CTCCAGATCA 
GCAGTTCAGG AGAGCACAGG AGGCAAAACA CAGATTGCTG GGCTTATTGG TGCCATCATC 
GTGCTGATTG TCGTTCTAGC CATTGGATTT CTCCTGGCGC CTCTACAAAA GTCCGTCCTG 
GCAGCTTTAG CATTGGGAAA CTTAAAGGGA ATGCTGATGC AGTTTGCTGA AATAGGCAGA 
TTGTGGCGAA AGGACAAATA TGATTGTTTA ATTTGGATCA TGACCTTCAT CTTCACCATT 
GTCCTGGGAC TCGGGTTAGG CCTGGCAGCT AGTGTGGCAT TTCAACTGCT AACCATCGTG 
TTCAGGACCC AATTTCCAAA ATGCAGCACG CTGGCTAATA TTGGAAGAAC CAACATCTAT 
AAGAATAAAA AAGATTATTA TGATATGTAT GAGCCAGAAG GAGTGAAAAT TTTCAGATGT 
CCATCTCCTA TCTACTTTGC AAACATTGGT TTCTTTAGGC GGAAACTTAT CGATGCTGTT 
GGCTTTAGTC CACTTCGAAT TCTACGCAAG CGCAACAAAG CTTTGAGGAA AATCCGAAAA 
CTGCAGAAGC AAGGCTTGCT ACAAGTGACA CCAAAAGGAT TTATATGTAC TGTTGACACC 
ATAAAAGATT CTGACGAAGA GCTGGACAAC AATCAGATAG AAGTACTGGA CCAGCCAATC 
AATACCACAG ACCTGCCTTT CCACATTGAC TGGAATGATG ATCTTCCTCT CAACATTGAG 
GTCCCCAAAA TCAGCCTCCA CAGCCTCATT CTTGACTTTT CAGCAGTGTC CTTTCTTGAT 
GTTTCTTCAG TGAGGGGCCT TAAATCGATT TTGCAAGAAT TTATCAGGAT CAAGGTAGAT 
GTGTATATCG TTGGAACTGA TGATGACTTC ATTGAGAAGC TTAACCGGTA TGAATTTTTT 
GATGGTGAAG TGAAAAGCTC AATATTTTTC TTAACAATCC ATGATGCTGT TTTGCATATT 
TTGATGAAGA AAGATTACAG TACTTCAAAG TTTAATCCCA GTCAGGAAAA AGATGGAAAA 
ATTGATTTTA CCATAAATAC AAATGGAGGA TTACGTAATC GGGTATATGA GGTGCCAGTT 
GAAACAAAAT TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011514169.1

Translation

MIEPFGNQYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGCDFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFRRKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDTIKDSDEELDNNQIEVLDQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVLHILMKKDYSTSKFNPSQEKDGKIDFTINTNGGLRNRVYEVPVETKF

Target ORF information:

RefSeq Version	XM_011515867.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens solute carrier family 26 (anion exchanger), member 3 (SLC26A3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011515867.1

ORF Insert Sequence:

ATGATTGAAC CCTTTGGGAA TCAGTATATT GTGGCCAGGC CAGTGTATTC TACAAATGCT 
TTTGAGGAAA ATCATAAAAA GACAGGAAGA CATCATAAGA CATTTCTGGA TCATCTCAAA 
GTGTGTTGTA GCTGTTCCCC ACAAAAGGCC AAGAGAATTG TCCTCTCTTT GTTCCCCATA 
GCATCTTGGT TGCCAGCATA CCGGCTTAAA GAATGGTTGC TCAGTGATAT TGTTTCTGGT 
ATCAGCACAG GGATTGTGGC CGTACTACAA GGTTTAGCAT TTGCTCTGCT GGTCGACATT 
CCCCCAGTCT ATGGGTTGTA TGCATCCTTT TTCCCAGCCA TAATCTACCT TTTCTTCGGC 
ACTTCCAGAC ACATATCCGT GGGTCCGTTT CCGATTCTGA GTATGATGGT GGGACTAGCA 
GTTTCAGGAG CAGTTTCAAA AGCAGTCCCA GATCGCAATG CAACTACTTT GGGATTGCCT 
AACAACTCGA ATAATTCTTC ACTACTGGAT GACGAGAGGG TGAGGGTGGC GGCGGCGGCA 
TCAGTCACAG TGCTTTCTGG AATCATCCAG TTGGCTTTTG GGATTCTGCG GATTGGATTT 
GTAGTGATAT ACCTGTCTGA GTCCCTCATC AGTGGCTTCA CTACTGCTGC TGCTGTTCAT 
GTTTTGGTTT CCCAACTCAA ATTCATTTTT CAGTTGACAG TCCCGTCACA CACTGATCCA 
GTTTCAATTT TCAAAGTACT ATACTCTGTA TTCTCACAAA TAGAGAAGAC TAATATTGCA 
GACCTGGTGA CAGCTCTGAT TGTCCTTTTG GTTGTATCCA TTGTTAAAGA AATAAATCAG 
CGCTTCAAAG ACAAACTTCC AGTGCCCATT CCAATCGAAT TCATTATGAC CGTGATTGCA 
GCAGGTGTAT CCTACGGCTG TGACTTTAAA AACAGGTTTA AAGTGGCTGT GGTTGGGGAC 
ATGAATCCTG GATTTCAGCC CCCTATTACA CCTGACGTGG AGACTTTCCA AAACACCGTA 
GGAGATTGCT TCGGCATCGC AATGGTTGCA TTTGCAGTGG CCTTTTCAGT TGCCAGCGTC 
TATTCCCTCA AATACGATTA TCCACTTGAT GGCAATCAGG AGTTAATAGC CTTGGGACTG 
GGTAACATAG TCTGTGGAGT ATTCAGAGGA TTTGCTGGGA GTACTGCCCT CTCCAGATCA 
GCAGTTCAGG AGAGCACAGG AGGCAAAACA CAGATTGCTG GGCTTATTGG TGCCATCATC 
GTGCTGATTG TCGTTCTAGC CATTGGATTT CTCCTGGCGC CTCTACAAAA GTCCGTCCTG 
GCAGCTTTAG CATTGGGAAA CTTAAAGGGA ATGCTGATGC AGTTTGCTGA AATAGGCAGA 
TTGTGGCGAA AGGACAAATA TGATTGTTTA ATTTGGATCA TGACCTTCAT CTTCACCATT 
GTCCTGGGAC TCGGGTTAGG CCTGGCAGCT AGTGTGGCAT TTCAACTGCT AACCATCGTG 
TTCAGGACCC AATTTCCAAA ATGCAGCACG CTGGCTAATA TTGGAAGAAC CAACATCTAT 
AAGAATAAAA AAGATTATTA TGATATGTAT GAGCCAGAAG GAGTGAAAAT TTTCAGATGT 
CCATCTCCTA TCTACTTTGC AAACATTGGT TTCTTTAGGC GGAAACTTAT CGATGCTGTT 
GGCTTTAGTC CACTTCGAAT TCTACGCAAG CGCAACAAAG CTTTGAGGAA AATCCGAAAA 
CTGCAGAAGC AAGGCTTGCT ACAAGTGACA CCAAAAGGAT TTATATGTAC TGTTGACACC 
ATAAAAGATT CTGACGAAGA GCTGGACAAC AATCAGATAG AAGTACTGGA CCAGCCAATC 
AATACCACAG ACCTGCCTTT CCACATTGAC TGGAATGATG ATCTTCCTCT CAACATTGAG 
GTCCCCAAAA TCAGCCTCCA CAGCCTCATT CTTGACTTTT CAGCAGTGTC CTTTCTTGAT 
GTTTCTTCAG TGAGGGGCCT TAAATCGATT TTGCAAGAAT TTATCAGGAT CAAGGTAGAT 
GTGTATATCG TTGGAACTGA TGATGACTTC ATTGAGAAGC TTAACCGGTA TGAATTTTTT 
GATGGTGAAG TGAAAAGCTC AATATTTTTC TTAACAATCC ATGATGCTGT TTTGCATATT 
TTGATGAAGA AAGATTACAG TACTTCAAAG TTTAATCCCA GTCAGGAAAA AGATGGAAAA 
ATTGATTTTA CCATAAATAC AAATGGAGGA TTACGTAATC GGGTATATGA GGTGCCAGTT 
GAAACAAAAT TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SLC26A3 (DRA) prevents TNF-alpha-induced barrier dysfunction and dextran sulfate sodium-induced acute colitis.
Laboratory investigation; a journal of technical methods and pathology(2018 Jan)
Ding X,Li D,Li M,Wang H,He Q,Wang Y,Yu H,Tian D,Yu Q

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SLC26A3 cDNA ORF clone, Homo sapiens(Human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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