| Gene Symbol | DNMT3A |
| Entrez Gene ID | 1788 |
| Full Name | DNA methyltransferase 3 alpha |
| Synonyms | DNMT3A2,M.HsaIIIA,TBRS |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016]. |
| Disorder MIM: | |
| Disorder Html: | Tatton-Brown-Rahman syndrome, 615879 (3) |









































User Manual