AGER cDNA ORF clone, Homo sapiens(human)

The following AGER gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AGER cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu26878 NM_001206934.1
Latest version!
Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 4, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$159.50-$223.30
$319.00
OHu27282 NM_001206966.1
Latest version!
Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 9, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$159.50-$223.30
$319.00
OHu27282 NM_001206940.1
Latest version!
Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 6, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$159.50-$223.30
$319.00
OHu27315 NM_001206929.1
Latest version!
Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$159.50-$223.30
$319.00
OHu27334 NM_001136.4
Latest version!
Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$189.50-$265.30
$379.00
OHu27399 NM_001206954.1
Latest version!
Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 8, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$99.50-$139.30
$199.00
OHu26803 NM_001206936.1
Latest version!
Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 5, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
OHu27251 NM_001206932.1
Latest version!
Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
OHu27340 NM_172197.2
Latest version!
Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 7, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $202.30
$289.00
OHu107680 NM_001136.5
Latest version!
Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OHu108645 NM_001206936.2
Latest version!
Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 5, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OHu108647 NM_001206932.2
Latest version!
Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OHu108654 NM_001206966.2
Latest version!
Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 9, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OHu108654 NM_001206940.2
Latest version!
Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 6, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OHu108658 NM_001206954.2
Latest version!
Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 8, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $139.30
$199.00
OHu108659 NM_172197.3
Latest version!
Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 7, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OHu96333 XM_017010328.2
Latest version!
Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
View Old Accession Versions >>
OHu96333 XM_017010328.1 Homo sapiens advanced glycosylation end product-specific receptor (AGER), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OHu26878
    Clone ID Related Accession (Same CDS sequence) NM_001206934.1
    Accession Version NM_001206934.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1092bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-15
    Organism Homo sapiens(human)
    Product advanced glycosylation end product-specific receptor isoform 4 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298100.1, AY755622.1 and BM971899.1. Transcript Variant: This variant (4, also known as RAGE_v6) lacks the penultimate coding exon, and uses alternate donor splice sites at two internal coding exons compared to variant 1. This results in a frame-shift and a shorter isoform (4) with a distinct C-terminus compared to isoform 1. Sequence Note: This Refseq, containing two in-frame translation initiation codons (at nt 8-10 and nt 101-103), is annotated with a CDS starting from the downstream AUG (dAUG) because the AGE receptor encoded by this gene is a known type 1 transmembrane protein requiring signal peptide for its function, and a signal peptide of 22 aa is predicted for the dAUG initiated protein. Translation initiation from the upstream AUG (uAUG) will add an extra 31 aa to the N-terminus, and no signal peptide is predicted for the uAUG initiated protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY755622.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2147920 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGGCAGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTAGTGGAAG AAAGCAGGAG AAGTAGAAAA CGGCCCTGTG AACAGGAGGT GGGGACATGT
    GTGTCAGAGG GAAGCTACCC TGCAGGGACT CTTAGCTGGC ACTTGGATGG GAAGCCCCTG
    GTGCCTAATG AGAAGGGAGT ATCTGTGAAG GAACAGACCA GGAGACACCC TGAGACAGGG
    CTCTTCACAC TGCAGTCGGA GCTAATGGTG ACCCCAGCCC GGGGAGGAGA TCCCCGTCCC
    ACCTTCTCCT GTAGCTTCAG CCCAGGCCTT CCCCGACACC GGGCCTTGCG CACAGCCCCC
    ATCCAGCCCC GTGTCTGGGA GCCTGTGCCT CTGGAGGAGG TCCAATTGGT GGTGGAGCCA
    GAAGGTGGAG CAGTAGCTCC TGGTGGAACC GTAACCCTGA CCTGTGAAGT CCCTGCCCAG
    CCCTCTCCTC AAATCCACTG GATGAAGGAT GGTGTGCCCT TGCCCCTTCC CCCCAGCCCT
    GTGCTGATCC TCCCTGAGAT AGGGCCTCAG GACCAGGGAA CCTACAGCTG TGTGGCCACC
    CATTCCAGCC ACGGGCCCCA GGAAAGCCGT GCTGTCAGCA TCAGCATCAT CGAACCAGGC
    GAGGAGGGGC CAACTGCAGG TGAGGGGTTT GATAAAGTCA GGGAAGCAGA AGATAGCCCC
    CAACACATGT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001193863.1
    CDS101..1192
    Translation

    Target ORF information:

    RefSeq Version NM_001206934.1
    Organism Homo sapiens(human)
    Definition Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 4, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001206934.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGGCAGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTAGTGGAAG AAAGCAGGAG AAGTAGAAAA CGGCCCTGTG AACAGGAGGT GGGGACATGT
    GTGTCAGAGG GAAGCTACCC TGCAGGGACT CTTAGCTGGC ACTTGGATGG GAAGCCCCTG
    GTGCCTAATG AGAAGGGAGT ATCTGTGAAG GAACAGACCA GGAGACACCC TGAGACAGGG
    CTCTTCACAC TGCAGTCGGA GCTAATGGTG ACCCCAGCCC GGGGAGGAGA TCCCCGTCCC
    ACCTTCTCCT GTAGCTTCAG CCCAGGCCTT CCCCGACACC GGGCCTTGCG CACAGCCCCC
    ATCCAGCCCC GTGTCTGGGA GCCTGTGCCT CTGGAGGAGG TCCAATTGGT GGTGGAGCCA
    GAAGGTGGAG CAGTAGCTCC TGGTGGAACC GTAACCCTGA CCTGTGAAGT CCCTGCCCAG
    CCCTCTCCTC AAATCCACTG GATGAAGGAT GGTGTGCCCT TGCCCCTTCC CCCCAGCCCT
    GTGCTGATCC TCCCTGAGAT AGGGCCTCAG GACCAGGGAA CCTACAGCTG TGTGGCCACC
    CATTCCAGCC ACGGGCCCCA GGAAAGCCGT GCTGTCAGCA TCAGCATCAT CGAACCAGGC
    GAGGAGGGGC CAACTGCAGG TGAGGGGTTT GATAAAGTCA GGGAAGCAGA AGATAGCCCC
    CAACACATGT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu27282
    Clone ID Related Accession (Same CDS sequence) NM_001206940.1 , NM_001206966.1
    Accession Version NM_001206940.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1044bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-03-03
    Organism Homo sapiens(human)
    Product advanced glycosylation end product-specific receptor isoform 6 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298100.1, AY755620.1 and BM971899.1. Transcript Variant: This variant (6, also known as RAGE_v1) lacks the penultimate coding exon, and uses an alternate donor splice site at another coding exon compared to variant 1. This results in a frame-shift and a shorter isoform (6, also known as esRAGE and soluble RAGE) with a distinct C-terminus compared to isoform 1. This isoform lacks the transmembrane and intracellular domains, is secreted (PMID:18089847), and thought to function as a decoy receptor that inhibits RAGE signaling, and thus prevent the pathological progression of some pathologic conditions, such as Alzheimer's disease (PMID:18431028). Variants 6 and 9 encode the same isoform. Sequence Note: This Refseq, containing two in-frame translation initiation codons (at nt 8-10 and nt 101-103), is annotated with a CDS starting from the downstream AUG (dAUG) because the AGE receptor encoded by this gene is a known type 1 transmembrane protein requiring signal peptide for its function, and a signal peptide of 22 aa is predicted for the dAUG initiated protein. Translation initiation from the upstream AUG (uAUG) will add an extra 31 aa to the N-terminus, and no signal peptide is predicted for the uAUG initiated protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB061668.1, AY755620.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2147920 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGCAGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATGGTGTGCC CTTGCCCCTT
    CCCCCCAGCC CTGTGCTGAT CCTCCCTGAG ATAGGGCCTC AGGACCAGGG AACCTACAGC
    TGTGTGGCCA CCCATTCCAG CCACGGGCCC CAGGAAAGCC GTGCTGTCAG CATCAGCATC
    ATCGAACCAG GCGAGGAGGG GCCAACTGCA GGTGAGGGGT TTGATAAAGT CAGGGAAGCA
    GAAGATAGCC CCCAACACAT GTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001193869.1
    CDS101..1144
    Translation

    Target ORF information:

    RefSeq Version NM_001206940.1
    Organism Homo sapiens(human)
    Definition Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 6, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001206940.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGCAGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATGGTGTGCC CTTGCCCCTT
    CCCCCCAGCC CTGTGCTGAT CCTCCCTGAG ATAGGGCCTC AGGACCAGGG AACCTACAGC
    TGTGTGGCCA CCCATTCCAG CCACGGGCCC CAGGAAAGCC GTGCTGTCAG CATCAGCATC
    ATCGAACCAG GCGAGGAGGG GCCAACTGCA GGTGAGGGGT TTGATAAAGT CAGGGAAGCA
    GAAGATAGCC CCCAACACAT GTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu27282
    Clone ID Related Accession (Same CDS sequence) NM_001206940.1 , NM_001206966.1
    Accession Version NM_001206966.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1044bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-03-03
    Organism Homo sapiens(human)
    Product advanced glycosylation end product-specific receptor isoform 6 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298100.1, AY755628.1 and BM971899.1. Transcript Variant: This variant (9, also known as RAGE_v10) lacks the penultimate coding exon, and uses alternate splice sites at other exons at the 3' end compared to variant 1. This results in a frame-shift and a shorter isoform (6, also known as esRAGE and soluble RAGE) with a distinct C-terminus compared to isoform 1. Variants 6 and 9 encode the same isoform. Sequence Note: This Refseq, containing two in-frame translation initiation codons (at nt 8-10 and nt 101-103), is annotated with a CDS starting from the downstream AUG (dAUG) because the AGE receptor encoded by this gene is a known type 1 transmembrane protein requiring signal peptide for its function, and a signal peptide of 22 aa is predicted for the dAUG initiated protein. Translation initiation from the upstream AUG (uAUG) will add an extra 31 aa to the N-terminus, and no signal peptide is predicted for the uAUG initiated protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY755628.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGCAGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATGGTGTGCC CTTGCCCCTT
    CCCCCCAGCC CTGTGCTGAT CCTCCCTGAG ATAGGGCCTC AGGACCAGGG AACCTACAGC
    TGTGTGGCCA CCCATTCCAG CCACGGGCCC CAGGAAAGCC GTGCTGTCAG CATCAGCATC
    ATCGAACCAG GCGAGGAGGG GCCAACTGCA GGTGAGGGGT TTGATAAAGT CAGGGAAGCA
    GAAGATAGCC CCCAACACAT GTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001193895.1
    CDS101..1144
    Translation

    Target ORF information:

    RefSeq Version NM_001206966.1
    Organism Homo sapiens(human)
    Definition Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 9, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001206966.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGCAGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATGGTGTGCC CTTGCCCCTT
    CCCCCCAGCC CTGTGCTGAT CCTCCCTGAG ATAGGGCCTC AGGACCAGGG AACCTACAGC
    TGTGTGGCCA CCCATTCCAG CCACGGGCCC CAGGAAAGCC GTGCTGTCAG CATCAGCATC
    ATCGAACCAG GCGAGGAGGG GCCAACTGCA GGTGAGGGGT TTGATAAAGT CAGGGAAGCA
    GAAGATAGCC CCCAACACAT GTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu27315
    Clone ID Related Accession (Same CDS sequence) NM_001206929.1
    Accession Version NM_001206929.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1263bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-15
    Organism Homo sapiens(human)
    Product advanced glycosylation end product-specific receptor isoform 2 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298100.1, AY755621.1 and BM971899.1. Transcript Variant: This variant (2, also known as RAGE_v5) uses an alternate in-frame donor splice site at an internal coding exon compared to variant 1. This results in a longer isoform (2) containing an additional protein segment compared to isoform 1. Sequence Note: This Refseq, containing two in-frame translation initiation codons (at nt 8-10 and nt 101-103), is annotated with a CDS starting from the downstream AUG (dAUG) because the AGE receptor encoded by this gene is a known type 1 transmembrane protein requiring signal peptide for its function, and a signal peptide of 22 aa is predicted for the dAUG initiated protein. Translation initiation from the upstream AUG (uAUG) will add an extra 31 aa to the N-terminus, and no signal peptide is predicted for the uAUG initiated protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY755621.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2147920 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGGCAGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTAGTGGAAG AAAGCAGGAG AAGTAGAAAA CGGCCCTGTG AACAGGAGGT GGGGACATGT
    GTGTCAGAGG GAAGCTACCC TGCAGGGACT CTTAGCTGGC ACTTGGATGG GAAGCCCCTG
    GTGCCTAATG AGAAGGGAGT ATCTGTGAAG GAACAGACCA GGAGACACCC TGAGACAGGG
    CTCTTCACAC TGCAGTCGGA GCTAATGGTG ACCCCAGCCC GGGGAGGAGA TCCCCGTCCC
    ACCTTCTCCT GTAGCTTCAG CCCAGGCCTT CCCCGACACC GGGCCTTGCG CACAGCCCCC
    ATCCAGCCCC GTGTCTGGGA GCCTGTGCCT CTGGAGGAGG TCCAATTGGT GGTGGAGCCA
    GAAGGTGGAG CAGTAGCTCC TGGTGGAACC GTAACCCTGA CCTGTGAAGT CCCTGCCCAG
    CCCTCTCCTC AAATCCACTG GATGAAGGAT GGTGTGCCCT TGCCCCTTCC CCCCAGCCCT
    GTGCTGATCC TCCCTGAGAT AGGGCCTCAG GACCAGGGAA CCTACAGCTG TGTGGCCACC
    CATTCCAGCC ACGGGCCCCA GGAAAGCCGT GCTGTCAGCA TCAGCATCAT CGAACCAGGC
    GAGGAGGGGC CAACTGCAGG CTCTGTGGGA GGATCAGGGC TGGGAACTCT AGCCCTGGCC
    CTGGGGATCC TGGGAGGCCT GGGGACAGCC GCCCTGCTCA TTGGGGTCAT CTTGTGGCAA
    AGGCGGCAAC GCCGAGGAGA GGAGAGGAAG GCCCCAGAAA ACCAGGAGGA AGAGGAGGAG
    CGTGCAGAAC TGAATCAGTC GGAGGAACCT GAGGCAGGCG AGAGTAGTAC TGGAGGGCCT
    TGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001193858.1
    CDS101..1363
    Translation

    Target ORF information:

    RefSeq Version NM_001206929.1
    Organism Homo sapiens(human)
    Definition Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001206929.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGGCAGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTAGTGGAAG AAAGCAGGAG AAGTAGAAAA CGGCCCTGTG AACAGGAGGT GGGGACATGT
    GTGTCAGAGG GAAGCTACCC TGCAGGGACT CTTAGCTGGC ACTTGGATGG GAAGCCCCTG
    GTGCCTAATG AGAAGGGAGT ATCTGTGAAG GAACAGACCA GGAGACACCC TGAGACAGGG
    CTCTTCACAC TGCAGTCGGA GCTAATGGTG ACCCCAGCCC GGGGAGGAGA TCCCCGTCCC
    ACCTTCTCCT GTAGCTTCAG CCCAGGCCTT CCCCGACACC GGGCCTTGCG CACAGCCCCC
    ATCCAGCCCC GTGTCTGGGA GCCTGTGCCT CTGGAGGAGG TCCAATTGGT GGTGGAGCCA
    GAAGGTGGAG CAGTAGCTCC TGGTGGAACC GTAACCCTGA CCTGTGAAGT CCCTGCCCAG
    CCCTCTCCTC AAATCCACTG GATGAAGGAT GGTGTGCCCT TGCCCCTTCC CCCCAGCCCT
    GTGCTGATCC TCCCTGAGAT AGGGCCTCAG GACCAGGGAA CCTACAGCTG TGTGGCCACC
    CATTCCAGCC ACGGGCCCCA GGAAAGCCGT GCTGTCAGCA TCAGCATCAT CGAACCAGGC
    GAGGAGGGGC CAACTGCAGG CTCTGTGGGA GGATCAGGGC TGGGAACTCT AGCCCTGGCC
    CTGGGGATCC TGGGAGGCCT GGGGACAGCC GCCCTGCTCA TTGGGGTCAT CTTGTGGCAA
    AGGCGGCAAC GCCGAGGAGA GGAGAGGAAG GCCCCAGAAA ACCAGGAGGA AGAGGAGGAG
    CGTGCAGAAC TGAATCAGTC GGAGGAACCT GAGGCAGGCG AGAGTAGTAC TGGAGGGCCT
    TGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu27334
    Clone ID Related Accession (Same CDS sequence) NM_001136.4
    Accession Version NM_001136.4 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1215bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2017-12-31
    Organism Homo sapiens(human)
    Product advanced glycosylation end product-specific receptor isoform 1 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298100.1 and BM971899.1. This sequence is a reference standard in the RefSeqGene project. On May 13, 2011 this sequence version replaced NM_001136.3. Transcript Variant: This variant (1, also known as RAGE) represents the predominant transcript, and encodes isoform 1. Sequence Note: This Refseq, containing two in-frame translation initiation codons (at nt 8-10 and nt 101-103), is annotated with a CDS starting from the downstream AUG (dAUG) because the AGE receptor encoded by this gene is a known type 1 transmembrane protein requiring signal peptide for its function, and a signal peptide of 22 aa is predicted for the dAUG initiated protein. Translation initiation from the upstream AUG (uAUG) will add an extra 31 aa to the N-terminus, and no signal peptide is predicted for the uAUG initiated protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M91211.1, AK298100.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2147920 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal (PMID:18089847) ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGGCAGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATGGTGTGCC CTTGCCCCTT
    CCCCCCAGCC CTGTGCTGAT CCTCCCTGAG ATAGGGCCTC AGGACCAGGG AACCTACAGC
    TGTGTGGCCA CCCATTCCAG CCACGGGCCC CAGGAAAGCC GTGCTGTCAG CATCAGCATC
    ATCGAACCAG GCGAGGAGGG GCCAACTGCA GGCTCTGTGG GAGGATCAGG GCTGGGAACT
    CTAGCCCTGG CCCTGGGGAT CCTGGGAGGC CTGGGGACAG CCGCCCTGCT CATTGGGGTC
    ATCTTGTGGC AAAGGCGGCA ACGCCGAGGA GAGGAGAGGA AGGCCCCAGA AAACCAGGAG
    GAAGAGGAGG AGCGTGCAGA ACTGAATCAG TCGGAGGAAC CTGAGGCAGG CGAGAGTAGT
    ACTGGAGGGC CTTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001127.1
    CDS101..1315
    Translation

    Target ORF information:

    RefSeq Version NM_001136.4
    Organism Homo sapiens(human)
    Definition Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001136.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGGCAGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATGGTGTGCC CTTGCCCCTT
    CCCCCCAGCC CTGTGCTGAT CCTCCCTGAG ATAGGGCCTC AGGACCAGGG AACCTACAGC
    TGTGTGGCCA CCCATTCCAG CCACGGGCCC CAGGAAAGCC GTGCTGTCAG CATCAGCATC
    ATCGAACCAG GCGAGGAGGG GCCAACTGCA GGCTCTGTGG GAGGATCAGG GCTGGGAACT
    CTAGCCCTGG CCCTGGGGAT CCTGGGAGGC CTGGGGACAG CCGCCCTGCT CATTGGGGTC
    ATCTTGTGGC AAAGGCGGCA ACGCCGAGGA GAGGAGAGGA AGGCCCCAGA AAACCAGGAG
    GAAGAGGAGG AGCGTGCAGA ACTGAATCAG TCGGAGGAAC CTGAGGCAGG CGAGAGTAGT
    ACTGGAGGGC CTTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu27399
    Clone ID Related Accession (Same CDS sequence) NM_001206954.1
    Accession Version NM_001206954.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 978bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-03-03
    Organism Homo sapiens(human)
    Product advanced glycosylation end product-specific receptor isoform 8 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298100.1, EU117141.1 and BM971899.1. Transcript Variant: This variant (8, also known as RAGE_v8) lacks two internal coding exons, and uses an alternate donor splice site at another coding exon compared to variant 1. This results in a frame-shift, and a shorter isoform (8) with a distinct C-terminus compared to isoform 1. Sequence Note: This Refseq, containing two in-frame translation initiation codons (at nt 8-10 and nt 101-103), is annotated with a CDS starting from the downstream AUG (dAUG) because the AGE receptor encoded by this gene is a known type 1 transmembrane protein requiring signal peptide for its function, and a signal peptide of 22 aa is predicted for the dAUG initiated protein. Translation initiation from the upstream AUG (uAUG) will add an extra 31 aa to the N-terminus, and no signal peptide is predicted for the uAUG initiated protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EU117141.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGCAGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATAACCAGGC GAGGAGGGGC
    CAACTGCAGG TGAGGGGTTT GATAAAGTCA GGGAAGCAGA AGATAGCCCC CAACACATGT
    GACTGGGGGG ATGGTCAACA AGAAAGGAAT GGAAGGCCCC AGAAAACCAG GAGGAAGAGG
    AGGAGCGTGC AGAACTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001193883.1
    CDS101..1078
    Translation

    Target ORF information:

    RefSeq Version NM_001206954.1
    Organism Homo sapiens(human)
    Definition Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 8, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001206954.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGCAGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATAACCAGGC GAGGAGGGGC
    CAACTGCAGG TGAGGGGTTT GATAAAGTCA GGGAAGCAGA AGATAGCCCC CAACACATGT
    GACTGGGGGG ATGGTCAACA AGAAAGGAAT GGAAGGCCCC AGAAAACCAG GAGGAAGAGG
    AGGAGCGTGC AGAACTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu26803
    Clone ID Related Accession (Same CDS sequence) NM_001206936.1
    Accession Version NM_001206936.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1068bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-03-03
    Organism Homo sapiens(human)
    Product advanced glycosylation end product-specific receptor isoform 5 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298100.1, AY755623.1 and BM971899.1. Transcript Variant: This variant (5, also known as RAGE_v9) lacks the penultimate coding exon, and uses alternate acceptor and donor splice sites at two internal coding exons compared to variant 1. This results in a frame-shift and a shorter isoform (5) with a distinct C-terminus compared to isoform 1. Sequence Note: This Refseq, containing two in-frame translation initiation codons (at nt 8-10 and nt 101-103), is annotated with a CDS starting from the downstream AUG (dAUG) because the AGE receptor encoded by this gene is a known type 1 transmembrane protein requiring signal peptide for its function, and a signal peptide of 22 aa is predicted for the dAUG initiated protein. Translation initiation from the upstream AUG (uAUG) will add an extra 31 aa to the N-terminus, and no signal peptide is predicted for the uAUG initiated protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY755623.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2147920 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGCAGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATGGCCTCAG GACCAGGGAA
    CCTACAGCTG TGTGGCCACC CATTCCAGCC ACGGGCCCCA GGAAAGCCGT GCTGTCAGCA
    TCAGCATCAT CGAACCAGGC GAGGAGGGGC CAACTGCAGG TGAGGGGTTT GATAAAGTCA
    GGGAAGCAGA AGATAGCCCC CAACACATGT GACTGGGGGG ATGGTCAACA AGAAAGGAAT
    GGAAGGCCCC AGAAAACCAG GAGGAAGAGG AGGAGCGTGC AGAACTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001193865.1
    CDS101..1168
    Translation

    Target ORF information:

    RefSeq Version NM_001206936.1
    Organism Homo sapiens(human)
    Definition Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 5, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001206936.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGCAGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATGGCCTCAG GACCAGGGAA
    CCTACAGCTG TGTGGCCACC CATTCCAGCC ACGGGCCCCA GGAAAGCCGT GCTGTCAGCA
    TCAGCATCAT CGAACCAGGC GAGGAGGGGC CAACTGCAGG TGAGGGGTTT GATAAAGTCA
    GGGAAGCAGA AGATAGCCCC CAACACATGT GACTGGGGGG ATGGTCAACA AGAAAGGAAT
    GGAAGGCCCC AGAAAACCAG GAGGAAGAGG AGGAGCGTGC AGAACTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu27251
    Clone ID Related Accession (Same CDS sequence) NM_001206932.1
    Accession Version NM_001206932.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1173bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-03-03
    Organism Homo sapiens(human)
    Product advanced glycosylation end product-specific receptor isoform 3 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298100.1, AY755624.1 and BM971899.1. Transcript Variant: This variant (3, also known as RAGE_v4) uses alternate in-frame acceptor and donor splice sites at two internal coding exons compared to variant 1. This results in a shorter isoform (2) missing two internal protein segments compared to isoform 1. Sequence Note: This Refseq, containing two in-frame translation initiation codons (at nt 8-10 and nt 101-103), is annotated with a CDS starting from the downstream AUG (dAUG) because the AGE receptor encoded by this gene is a known type 1 transmembrane protein requiring signal peptide for its function, and a signal peptide of 22 aa is predicted for the dAUG initiated protein. Translation initiation from the upstream AUG (uAUG) will add an extra 31 aa to the N-terminus, and no signal peptide is predicted for the uAUG initiated protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY755624.1, DQ104252.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2147920 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGGCAGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGG GAGGAGGCCC CTGGGACAGT
    GTGGCTCGTG TCCTTCCCAA CGGCTCCCTC TTCCTTCCGG CTGTCGGGAT CCAGGATGAG
    GGGATTTTCC GGTGCCAGGC AATGAACAGG AATGGAAAGG AGACCAAGTC CAACTACCGA
    GTCCGTGTCT ACCAGATTCC TGGGAAGCCA GAAATTGTAG ATTCTGCCTC TGAACTCACG
    GCTGGTGTTC CCAATAAGGT GGGGACATGT GTGTCAGAGG GAAGCTACCC TGCAGGGACT
    CTTAGCTGGC ACTTGGATGG GAAGCCCCTG GTGCCTAATG AGAAGGGAGT ATCTGTGAAG
    GAACAGACCA GGAGACACCC TGAGACAGGG CTCTTCACAC TGCAGTCGGA GCTAATGGTG
    ACCCCAGCCC GGGGAGGAGA TCCCCGTCCC ACCTTCTCCT GTAGCTTCAG CCCAGGCCTT
    CCCCGACACC GGGCCTTGCG CACAGCCCCC ATCCAGCCCC GTGTCTGGGA GCCTGTGCCT
    CTGGAGGAGG TCCAATTGGT GGTGGAGCCA GAAGGTGGAG CAGTAGCTCC TGGTGGAACC
    GTAACCCTGA CCTGTGAAGT CCCTGCCCAG CCCTCTCCTC AAATCCACTG GATGAAGGAT
    GGTGTGCCCT TGCCCCTTCC CCCCAGCCCT GTGCTGATCC TCCCTGAGAT AGGGCCTCAG
    GACCAGGGAA CCTACAGCTG TGTGGCCACC CATTCCAGCC ACGGGCCCCA GGAAAGCCGT
    GCTGTCAGCA TCAGCATCAT CGAACCAGGC GAGGAGGGGC CAACTGCAGG CTCTGTGGGA
    GGATCAGGGC TGGGAACTCT AGCCCTGGCC CTGGGGATCC TGGGAGGCCT GGGGACAGCC
    GCCCTGCTCA TTGGGGTCAT CTTGTGGCAA AGGCGGCAAC GCCGAGGAGA GGAGAGGAAG
    GCCCCAGAAA ACCAGGAGGA AGAGGAGGAG CGTGCAGAAC TGAATCAGTC GGAGGAACCT
    GAGGCAGGCG AGAGTAGTAC TGGAGGGCCT TGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001193861.1
    CDS101..1273
    Translation

    Target ORF information:

    RefSeq Version NM_001206932.1
    Organism Homo sapiens(human)
    Definition Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 3, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001206932.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGGCAGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGG GAGGAGGCCC CTGGGACAGT
    GTGGCTCGTG TCCTTCCCAA CGGCTCCCTC TTCCTTCCGG CTGTCGGGAT CCAGGATGAG
    GGGATTTTCC GGTGCCAGGC AATGAACAGG AATGGAAAGG AGACCAAGTC CAACTACCGA
    GTCCGTGTCT ACCAGATTCC TGGGAAGCCA GAAATTGTAG ATTCTGCCTC TGAACTCACG
    GCTGGTGTTC CCAATAAGGT GGGGACATGT GTGTCAGAGG GAAGCTACCC TGCAGGGACT
    CTTAGCTGGC ACTTGGATGG GAAGCCCCTG GTGCCTAATG AGAAGGGAGT ATCTGTGAAG
    GAACAGACCA GGAGACACCC TGAGACAGGG CTCTTCACAC TGCAGTCGGA GCTAATGGTG
    ACCCCAGCCC GGGGAGGAGA TCCCCGTCCC ACCTTCTCCT GTAGCTTCAG CCCAGGCCTT
    CCCCGACACC GGGCCTTGCG CACAGCCCCC ATCCAGCCCC GTGTCTGGGA GCCTGTGCCT
    CTGGAGGAGG TCCAATTGGT GGTGGAGCCA GAAGGTGGAG CAGTAGCTCC TGGTGGAACC
    GTAACCCTGA CCTGTGAAGT CCCTGCCCAG CCCTCTCCTC AAATCCACTG GATGAAGGAT
    GGTGTGCCCT TGCCCCTTCC CCCCAGCCCT GTGCTGATCC TCCCTGAGAT AGGGCCTCAG
    GACCAGGGAA CCTACAGCTG TGTGGCCACC CATTCCAGCC ACGGGCCCCA GGAAAGCCGT
    GCTGTCAGCA TCAGCATCAT CGAACCAGGC GAGGAGGGGC CAACTGCAGG CTCTGTGGGA
    GGATCAGGGC TGGGAACTCT AGCCCTGGCC CTGGGGATCC TGGGAGGCCT GGGGACAGCC
    GCCCTGCTCA TTGGGGTCAT CTTGTGGCAA AGGCGGCAAC GCCGAGGAGA GGAGAGGAAG
    GCCCCAGAAA ACCAGGAGGA AGAGGAGGAG CGTGCAGAAC TGAATCAGTC GGAGGAACCT
    GAGGCAGGCG AGAGTAGTAC TGGAGGGCCT TGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu27340
    Clone ID Related Accession (Same CDS sequence) NM_172197.2
    Accession Version NM_172197.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1029bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-03-03
    Organism Homo sapiens(human)
    Product advanced glycosylation end product-specific receptor isoform 7 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298100.1, AJ133822.1 and BM971899.1. On May 13, 2011 this sequence version replaced NM_172197.1. Transcript Variant: This variant (7, also known as RAGE_v16) uses alternate splice sites at several internal coding exons compared to variant 1. This results in a frame-shift and a shorter isoform (7, also known as hRAGEsec) with a distinct C-terminus compared to isoform 1. Sequence Note: This Refseq, containing two in-frame translation initiation codons (at nt 8-10 and nt 101-103), is annotated with a CDS starting from the downstream AUG (dAUG) because the AGE receptor encoded by this gene is a known type 1 transmembrane protein requiring signal peptide for its function, and a signal peptide of 22 aa is predicted for the dAUG initiated protein. Translation initiation from the upstream AUG (uAUG) will add an extra 31 aa to the N-terminus, and no signal peptide is predicted for the uAUG initiated protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ133822.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142363, SAMEA2147920 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGCAGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGG GAGGAGGCCC CTGGGACAGT
    GTGGCTCGTG TCCTTCCCAA CGGCTCCCTC TTCCTTCCGG CTGTCGGGAT CCAGGATGAG
    GGGATTTTCC GGTGCCAGGC AATGAACAGG AATGGAAAGG AGACCAAGTC CAACTACCGA
    GTCCGTGTCT ACCAGATTCC TGGGAAGCCA GAAATTGTAG ATTCTGCCTC TGAACTCACG
    GCTGGTGTTC CCAATAAGGT GGGGACATGT GTGTCAGAGG GAAGCTACCC TGCAGGGACT
    CTTAGCTGGC ACTTGGATGG GAAGCCCCTG GTGCCTAATG AGAAGGGAGT ATCTGTGAAG
    GAACAGACCA GGAGACACCC TGAGACAGGG CTCTTCACAC TGCAGTCGGA GCTAATGGTG
    ACCCCAGCCC GGGGAGGAGA TCCCCGTCCC ACCTTCTCCT GTAGCTTCAG CCCAGGCCTT
    CCCCGACACC GGGCCTTGCG CACAGCCCCC ATCCAGCCCC GTGTCTGGGA GCCTGTGCCT
    CTGGAGGAGG TCCAATTGGT GGTGGAGCCA GAAGGTGGAG CAGTAGCTCC TGGTGGAACC
    GTAACCCTGA CCTGTGAAGT CCCTGCCCAG CCCTCTCCTC AAATCCACTG GATGAAGGAT
    GTGAGTGACC TGGAGAGAGG GGCTGGGAGA ACCAGGCGAG GAGGGGCCAA CTGCAGGCTC
    TGTGGGAGGA TCAGGGCTGG GAACTCTAGC CCTGGCCCTG GGGATCCTGG GAGGCCTGGG
    GACAGCCGCC CTGCTCATTG GGGTCATCTT GTGGCAAAGG CGGCAACGCC GAGGAGAGGA
    GAGGAAGGCC CCAGAAAACC AGGAGGAAGA GGAGGAGCGT GCAGAACTGA ATCAGTCGGA
    GGAACCTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_751947.1
    CDS101..1129
    Translation

    Target ORF information:

    RefSeq Version NM_172197.2
    Organism Homo sapiens(human)
    Definition Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 7, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_172197.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGCAGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGG GAGGAGGCCC CTGGGACAGT
    GTGGCTCGTG TCCTTCCCAA CGGCTCCCTC TTCCTTCCGG CTGTCGGGAT CCAGGATGAG
    GGGATTTTCC GGTGCCAGGC AATGAACAGG AATGGAAAGG AGACCAAGTC CAACTACCGA
    GTCCGTGTCT ACCAGATTCC TGGGAAGCCA GAAATTGTAG ATTCTGCCTC TGAACTCACG
    GCTGGTGTTC CCAATAAGGT GGGGACATGT GTGTCAGAGG GAAGCTACCC TGCAGGGACT
    CTTAGCTGGC ACTTGGATGG GAAGCCCCTG GTGCCTAATG AGAAGGGAGT ATCTGTGAAG
    GAACAGACCA GGAGACACCC TGAGACAGGG CTCTTCACAC TGCAGTCGGA GCTAATGGTG
    ACCCCAGCCC GGGGAGGAGA TCCCCGTCCC ACCTTCTCCT GTAGCTTCAG CCCAGGCCTT
    CCCCGACACC GGGCCTTGCG CACAGCCCCC ATCCAGCCCC GTGTCTGGGA GCCTGTGCCT
    CTGGAGGAGG TCCAATTGGT GGTGGAGCCA GAAGGTGGAG CAGTAGCTCC TGGTGGAACC
    GTAACCCTGA CCTGTGAAGT CCCTGCCCAG CCCTCTCCTC AAATCCACTG GATGAAGGAT
    GTGAGTGACC TGGAGAGAGG GGCTGGGAGA ACCAGGCGAG GAGGGGCCAA CTGCAGGCTC
    TGTGGGAGGA TCAGGGCTGG GAACTCTAGC CCTGGCCCTG GGGATCCTGG GAGGCCTGGG
    GACAGCCGCC CTGCTCATTG GGGTCATCTT GTGGCAAAGG CGGCAACGCC GAGGAGAGGA
    GAGGAAGGCC CCAGAAAACC AGGAGGAAGA GGAGGAGCGT GCAGAACTGA ATCAGTCGGA
    GGAACCTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu107680
    Clone ID Related Accession (Same CDS sequence) NM_001136.5
    Accession Version NM_001136.5 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1215bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-15
    Organism Homo sapiens(human)
    Product advanced glycosylation end product-specific receptor isoform 1 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL662884.11. On Nov 24, 2018 this sequence version replaced NM_001136.4. Transcript Variant: This variant (1, also known as RAGE) represents the predominant transcript, and encodes isoform 1. Sequence Note: This Refseq, containing two in-frame translation initiation codons (at nt 8-10 and nt 101-103), is annotated with a CDS starting from the downstream AUG (dAUG) because the AGE receptor encoded by this gene is a known type 1 transmembrane protein requiring signal peptide for its function, and a signal peptide of 22 aa is predicted for the dAUG initiated protein. Translation initiation from the upstream AUG (uAUG) will add an extra 31 aa to the N-terminus, and no signal peptide is predicted for the uAUG initiated protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279847.2396.1, AK298100.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2147920 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000375076.9/ ENSP00000364217.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGGCTGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATGGTGTGCC CTTGCCCCTT
    CCCCCCAGCC CTGTGCTGAT CCTCCCTGAG ATAGGGCCTC AGGACCAGGG AACCTACAGC
    TGTGTGGCCA CCCATTCCAG CCACGGGCCC CAGGAAAGCC GTGCTGTCAG CATCAGCATC
    ATCGAACCAG GCGAGGAGGG GCCAACTGCA GGCTCTGTGG GAGGATCAGG GCTGGGAACT
    CTAGCCCTGG CCCTGGGGAT CCTGGGAGGC CTGGGGACAG CCGCCCTGCT CATTGGGGTC
    ATCTTGTGGC AAAGGCGGCA ACGCCGAGGA GAGGAGAGGA AGGCCCCAGA AAACCAGGAG
    GAAGAGGAGG AGCGTGCAGA ACTGAATCAG TCGGAGGAAC CTGAGGCAGG CGAGAGTAGT
    ACTGGAGGGC CTTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001127.1
    CDS32..1246
    Translation

    Target ORF information:

    RefSeq Version NM_001136.5
    Organism Homo sapiens(human)
    Definition Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001136.5

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGGCTGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATGGTGTGCC CTTGCCCCTT
    CCCCCCAGCC CTGTGCTGAT CCTCCCTGAG ATAGGGCCTC AGGACCAGGG AACCTACAGC
    TGTGTGGCCA CCCATTCCAG CCACGGGCCC CAGGAAAGCC GTGCTGTCAG CATCAGCATC
    ATCGAACCAG GCGAGGAGGG GCCAACTGCA GGCTCTGTGG GAGGATCAGG GCTGGGAACT
    CTAGCCCTGG CCCTGGGGAT CCTGGGAGGC CTGGGGACAG CCGCCCTGCT CATTGGGGTC
    ATCTTGTGGC AAAGGCGGCA ACGCCGAGGA GAGGAGAGGA AGGCCCCAGA AAACCAGGAG
    GAAGAGGAGG AGCGTGCAGA ACTGAATCAG TCGGAGGAAC CTGAGGCAGG CGAGAGTAGT
    ACTGGAGGGC CTTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu108645
    Clone ID Related Accession (Same CDS sequence) NM_001206936.2
    Accession Version NM_001206936.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1068bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-15
    Organism Homo sapiens(human)
    Product advanced glycosylation end product-specific receptor isoform 5 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL662884.11. On Jun 3, 2019 this sequence version replaced NM_001206936.1. Transcript Variant: This variant (5, also known as RAGE_v9) lacks the penultimate coding exon, and uses alternate acceptor and donor splice sites at two internal coding exons compared to variant 1. This results in a frame-shift and a shorter isoform (5) with a distinct C-terminus compared to isoform 1. Sequence Note: This Refseq, containing two in-frame translation initiation codons (at nt 8-10 and nt 101-103), is annotated with a CDS starting from the downstream AUG (dAUG) because the AGE receptor encoded by this gene is a known type 1 transmembrane protein requiring signal peptide for its function, and a signal peptide of 22 aa is predicted for the dAUG initiated protein. Translation initiation from the upstream AUG (uAUG) will add an extra 31 aa to the N-terminus, and no signal peptide is predicted for the uAUG initiated protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY755623.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2147920 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGCTGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATGGCCTCAG GACCAGGGAA
    CCTACAGCTG TGTGGCCACC CATTCCAGCC ACGGGCCCCA GGAAAGCCGT GCTGTCAGCA
    TCAGCATCAT CGAACCAGGC GAGGAGGGGC CAACTGCAGG TGAGGGGTTT GATAAAGTCA
    GGGAAGCAGA AGATAGCCCC CAACACATGT GACTGGGGGG ATGGTCAACA AGAAAGGAAT
    GGAAGGCCCC AGAAAACCAG GAGGAAGAGG AGGAGCGTGC AGAACTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001193865.1
    CDS32..1099
    Translation

    Target ORF information:

    RefSeq Version NM_001206936.2
    Organism Homo sapiens(human)
    Definition Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 5, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001206936.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGCTGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATGGCCTCAG GACCAGGGAA
    CCTACAGCTG TGTGGCCACC CATTCCAGCC ACGGGCCCCA GGAAAGCCGT GCTGTCAGCA
    TCAGCATCAT CGAACCAGGC GAGGAGGGGC CAACTGCAGG TGAGGGGTTT GATAAAGTCA
    GGGAAGCAGA AGATAGCCCC CAACACATGT GACTGGGGGG ATGGTCAACA AGAAAGGAAT
    GGAAGGCCCC AGAAAACCAG GAGGAAGAGG AGGAGCGTGC AGAACTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu108647
    Clone ID Related Accession (Same CDS sequence) NM_001206932.2
    Accession Version NM_001206932.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1173bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-15
    Organism Homo sapiens(human)
    Product advanced glycosylation end product-specific receptor isoform 3 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL662884.11. On Jun 3, 2019 this sequence version replaced NM_001206932.1. Transcript Variant: This variant (3, also known as RAGE_v4) uses alternate in-frame acceptor and donor splice sites at two internal coding exons compared to variant 1. This results in a shorter isoform (2) missing two internal protein segments compared to isoform 1. Sequence Note: This Refseq, containing two in-frame translation initiation codons (at nt 8-10 and nt 101-103), is annotated with a CDS starting from the downstream AUG (dAUG) because the AGE receptor encoded by this gene is a known type 1 transmembrane protein requiring signal peptide for its function, and a signal peptide of 22 aa is predicted for the dAUG initiated protein. Translation initiation from the upstream AUG (uAUG) will add an extra 31 aa to the N-terminus, and no signal peptide is predicted for the uAUG initiated protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ104252.1, AY755624.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2147920 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGGCTGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGG GAGGAGGCCC CTGGGACAGT
    GTGGCTCGTG TCCTTCCCAA CGGCTCCCTC TTCCTTCCGG CTGTCGGGAT CCAGGATGAG
    GGGATTTTCC GGTGCCAGGC AATGAACAGG AATGGAAAGG AGACCAAGTC CAACTACCGA
    GTCCGTGTCT ACCAGATTCC TGGGAAGCCA GAAATTGTAG ATTCTGCCTC TGAACTCACG
    GCTGGTGTTC CCAATAAGGT GGGGACATGT GTGTCAGAGG GAAGCTACCC TGCAGGGACT
    CTTAGCTGGC ACTTGGATGG GAAGCCCCTG GTGCCTAATG AGAAGGGAGT ATCTGTGAAG
    GAACAGACCA GGAGACACCC TGAGACAGGG CTCTTCACAC TGCAGTCGGA GCTAATGGTG
    ACCCCAGCCC GGGGAGGAGA TCCCCGTCCC ACCTTCTCCT GTAGCTTCAG CCCAGGCCTT
    CCCCGACACC GGGCCTTGCG CACAGCCCCC ATCCAGCCCC GTGTCTGGGA GCCTGTGCCT
    CTGGAGGAGG TCCAATTGGT GGTGGAGCCA GAAGGTGGAG CAGTAGCTCC TGGTGGAACC
    GTAACCCTGA CCTGTGAAGT CCCTGCCCAG CCCTCTCCTC AAATCCACTG GATGAAGGAT
    GGTGTGCCCT TGCCCCTTCC CCCCAGCCCT GTGCTGATCC TCCCTGAGAT AGGGCCTCAG
    GACCAGGGAA CCTACAGCTG TGTGGCCACC CATTCCAGCC ACGGGCCCCA GGAAAGCCGT
    GCTGTCAGCA TCAGCATCAT CGAACCAGGC GAGGAGGGGC CAACTGCAGG CTCTGTGGGA
    GGATCAGGGC TGGGAACTCT AGCCCTGGCC CTGGGGATCC TGGGAGGCCT GGGGACAGCC
    GCCCTGCTCA TTGGGGTCAT CTTGTGGCAA AGGCGGCAAC GCCGAGGAGA GGAGAGGAAG
    GCCCCAGAAA ACCAGGAGGA AGAGGAGGAG CGTGCAGAAC TGAATCAGTC GGAGGAACCT
    GAGGCAGGCG AGAGTAGTAC TGGAGGGCCT TGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001193861.1
    CDS32..1204
    Translation

    Target ORF information:

    RefSeq Version NM_001206932.2
    Organism Homo sapiens(human)
    Definition Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 3, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001206932.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGGCTGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGG GAGGAGGCCC CTGGGACAGT
    GTGGCTCGTG TCCTTCCCAA CGGCTCCCTC TTCCTTCCGG CTGTCGGGAT CCAGGATGAG
    GGGATTTTCC GGTGCCAGGC AATGAACAGG AATGGAAAGG AGACCAAGTC CAACTACCGA
    GTCCGTGTCT ACCAGATTCC TGGGAAGCCA GAAATTGTAG ATTCTGCCTC TGAACTCACG
    GCTGGTGTTC CCAATAAGGT GGGGACATGT GTGTCAGAGG GAAGCTACCC TGCAGGGACT
    CTTAGCTGGC ACTTGGATGG GAAGCCCCTG GTGCCTAATG AGAAGGGAGT ATCTGTGAAG
    GAACAGACCA GGAGACACCC TGAGACAGGG CTCTTCACAC TGCAGTCGGA GCTAATGGTG
    ACCCCAGCCC GGGGAGGAGA TCCCCGTCCC ACCTTCTCCT GTAGCTTCAG CCCAGGCCTT
    CCCCGACACC GGGCCTTGCG CACAGCCCCC ATCCAGCCCC GTGTCTGGGA GCCTGTGCCT
    CTGGAGGAGG TCCAATTGGT GGTGGAGCCA GAAGGTGGAG CAGTAGCTCC TGGTGGAACC
    GTAACCCTGA CCTGTGAAGT CCCTGCCCAG CCCTCTCCTC AAATCCACTG GATGAAGGAT
    GGTGTGCCCT TGCCCCTTCC CCCCAGCCCT GTGCTGATCC TCCCTGAGAT AGGGCCTCAG
    GACCAGGGAA CCTACAGCTG TGTGGCCACC CATTCCAGCC ACGGGCCCCA GGAAAGCCGT
    GCTGTCAGCA TCAGCATCAT CGAACCAGGC GAGGAGGGGC CAACTGCAGG CTCTGTGGGA
    GGATCAGGGC TGGGAACTCT AGCCCTGGCC CTGGGGATCC TGGGAGGCCT GGGGACAGCC
    GCCCTGCTCA TTGGGGTCAT CTTGTGGCAA AGGCGGCAAC GCCGAGGAGA GGAGAGGAAG
    GCCCCAGAAA ACCAGGAGGA AGAGGAGGAG CGTGCAGAAC TGAATCAGTC GGAGGAACCT
    GAGGCAGGCG AGAGTAGTAC TGGAGGGCCT TGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu108654
    Clone ID Related Accession (Same CDS sequence) NM_001206966.2 , NM_001206940.2
    Accession Version NM_001206966.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1044bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-15
    Organism Homo sapiens(human)
    Product advanced glycosylation end product-specific receptor isoform 6 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL662884.11. On Jun 3, 2019 this sequence version replaced NM_001206966.1. Transcript Variant: This variant (9, also known as RAGE_v10) lacks the penultimate coding exon, and uses alternate splice sites at other exons at the 3' end compared to variant 1. This results in a frame-shift and a shorter isoform (6, also known as esRAGE and soluble RAGE) with a distinct C-terminus compared to isoform 1. Variants 6 and 9 encode the same isoform. Sequence Note: This Refseq, containing two in-frame translation initiation codons (at nt 8-10 and nt 101-103), is annotated with a CDS starting from the downstream AUG (dAUG) because the AGE receptor encoded by this gene is a known type 1 transmembrane protein requiring signal peptide for its function, and a signal peptide of 22 aa is predicted for the dAUG initiated protein. Translation initiation from the upstream AUG (uAUG) will add an extra 31 aa to the N-terminus, and no signal peptide is predicted for the uAUG initiated protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY755628.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGCTGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATGGTGTGCC CTTGCCCCTT
    CCCCCCAGCC CTGTGCTGAT CCTCCCTGAG ATAGGGCCTC AGGACCAGGG AACCTACAGC
    TGTGTGGCCA CCCATTCCAG CCACGGGCCC CAGGAAAGCC GTGCTGTCAG CATCAGCATC
    ATCGAACCAG GCGAGGAGGG GCCAACTGCA GGTGAGGGGT TTGATAAAGT CAGGGAAGCA
    GAAGATAGCC CCCAACACAT GTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001193895.1
    CDS32..1075
    Translation

    Target ORF information:

    RefSeq Version NM_001206966.2
    Organism Homo sapiens(human)
    Definition Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 9, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001206966.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGCTGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATGGTGTGCC CTTGCCCCTT
    CCCCCCAGCC CTGTGCTGAT CCTCCCTGAG ATAGGGCCTC AGGACCAGGG AACCTACAGC
    TGTGTGGCCA CCCATTCCAG CCACGGGCCC CAGGAAAGCC GTGCTGTCAG CATCAGCATC
    ATCGAACCAG GCGAGGAGGG GCCAACTGCA GGTGAGGGGT TTGATAAAGT CAGGGAAGCA
    GAAGATAGCC CCCAACACAT GTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu108654
    Clone ID Related Accession (Same CDS sequence) NM_001206966.2 , NM_001206940.2
    Accession Version NM_001206940.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1044bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-15
    Organism Homo sapiens(human)
    Product advanced glycosylation end product-specific receptor isoform 6 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL662884.11. On Jun 3, 2019 this sequence version replaced NM_001206940.1. Transcript Variant: This variant (6, also known as RAGE_v1) lacks the penultimate coding exon, and uses an alternate donor splice site at another coding exon compared to variant 1. This results in a frame-shift and a shorter isoform (6, also known as esRAGE and soluble RAGE) with a distinct C-terminus compared to isoform 1. This isoform lacks the transmembrane and intracellular domains, is secreted (PMID:18089847), and thought to function as a decoy receptor that inhibits RAGE signaling, and thus prevent the pathological progression of some pathologic conditions, such as Alzheimer's disease (PMID:18431028). Variants 6 and 9 encode the same isoform. Sequence Note: This Refseq, containing two in-frame translation initiation codons (at nt 8-10 and nt 101-103), is annotated with a CDS starting from the downstream AUG (dAUG) because the AGE receptor encoded by this gene is a known type 1 transmembrane protein requiring signal peptide for its function, and a signal peptide of 22 aa is predicted for the dAUG initiated protein. Translation initiation from the upstream AUG (uAUG) will add an extra 31 aa to the N-terminus, and no signal peptide is predicted for the uAUG initiated protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB061668.1, AY755620.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2147920 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGCTGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATGGTGTGCC CTTGCCCCTT
    CCCCCCAGCC CTGTGCTGAT CCTCCCTGAG ATAGGGCCTC AGGACCAGGG AACCTACAGC
    TGTGTGGCCA CCCATTCCAG CCACGGGCCC CAGGAAAGCC GTGCTGTCAG CATCAGCATC
    ATCGAACCAG GCGAGGAGGG GCCAACTGCA GGTGAGGGGT TTGATAAAGT CAGGGAAGCA
    GAAGATAGCC CCCAACACAT GTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001193869.1
    CDS32..1075
    Translation

    Target ORF information:

    RefSeq Version NM_001206940.2
    Organism Homo sapiens(human)
    Definition Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 6, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001206940.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGCTGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATGGTGTGCC CTTGCCCCTT
    CCCCCCAGCC CTGTGCTGAT CCTCCCTGAG ATAGGGCCTC AGGACCAGGG AACCTACAGC
    TGTGTGGCCA CCCATTCCAG CCACGGGCCC CAGGAAAGCC GTGCTGTCAG CATCAGCATC
    ATCGAACCAG GCGAGGAGGG GCCAACTGCA GGTGAGGGGT TTGATAAAGT CAGGGAAGCA
    GAAGATAGCC CCCAACACAT GTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu108658
    Clone ID Related Accession (Same CDS sequence) NM_001206954.2
    Accession Version NM_001206954.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 978bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-15
    Organism Homo sapiens(human)
    Product advanced glycosylation end product-specific receptor isoform 8 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL662884.11. On Jun 3, 2019 this sequence version replaced NM_001206954.1. Transcript Variant: This variant (8, also known as RAGE_v8) lacks two internal coding exons, and uses an alternate donor splice site at another coding exon compared to variant 1. This results in a frame-shift, and a shorter isoform (8) with a distinct C-terminus compared to isoform 1. Sequence Note: This Refseq, containing two in-frame translation initiation codons (at nt 8-10 and nt 101-103), is annotated with a CDS starting from the downstream AUG (dAUG) because the AGE receptor encoded by this gene is a known type 1 transmembrane protein requiring signal peptide for its function, and a signal peptide of 22 aa is predicted for the dAUG initiated protein. Translation initiation from the upstream AUG (uAUG) will add an extra 31 aa to the N-terminus, and no signal peptide is predicted for the uAUG initiated protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EU117141.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGCTGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATAACCAGGC GAGGAGGGGC
    CAACTGCAGG TGAGGGGTTT GATAAAGTCA GGGAAGCAGA AGATAGCCCC CAACACATGT
    GACTGGGGGG ATGGTCAACA AGAAAGGAAT GGAAGGCCCC AGAAAACCAG GAGGAAGAGG
    AGGAGCGTGC AGAACTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001193883.1
    CDS32..1009
    Translation

    Target ORF information:

    RefSeq Version NM_001206954.2
    Organism Homo sapiens(human)
    Definition Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 8, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001206954.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGCTGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGA ACACAGGCCG GACAGAAGCT
    TGGAAGGTCC TGTCTCCCCA GGGAGGAGGC CCCTGGGACA GTGTGGCTCG TGTCCTTCCC
    AACGGCTCCC TCTTCCTTCC GGCTGTCGGG ATCCAGGATG AGGGGATTTT CCGGTGCCAG
    GCAATGAACA GGAATGGAAA GGAGACCAAG TCCAACTACC GAGTCCGTGT CTACCAGATT
    CCTGGGAAGC CAGAAATTGT AGATTCTGCC TCTGAACTCA CGGCTGGTGT TCCCAATAAG
    GTGGGGACAT GTGTGTCAGA GGGAAGCTAC CCTGCAGGGA CTCTTAGCTG GCACTTGGAT
    GGGAAGCCCC TGGTGCCTAA TGAGAAGGGA GTATCTGTGA AGGAACAGAC CAGGAGACAC
    CCTGAGACAG GGCTCTTCAC ACTGCAGTCG GAGCTAATGG TGACCCCAGC CCGGGGAGGA
    GATCCCCGTC CCACCTTCTC CTGTAGCTTC AGCCCAGGCC TTCCCCGACA CCGGGCCTTG
    CGCACAGCCC CCATCCAGCC CCGTGTCTGG GAGCCTGTGC CTCTGGAGGA GGTCCAATTG
    GTGGTGGAGC CAGAAGGTGG AGCAGTAGCT CCTGGTGGAA CCGTAACCCT GACCTGTGAA
    GTCCCTGCCC AGCCCTCTCC TCAAATCCAC TGGATGAAGG ATAACCAGGC GAGGAGGGGC
    CAACTGCAGG TGAGGGGTTT GATAAAGTCA GGGAAGCAGA AGATAGCCCC CAACACATGT
    GACTGGGGGG ATGGTCAACA AGAAAGGAAT GGAAGGCCCC AGAAAACCAG GAGGAAGAGG
    AGGAGCGTGC AGAACTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu108659
    Clone ID Related Accession (Same CDS sequence) NM_172197.3
    Accession Version NM_172197.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1029bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-15
    Organism Homo sapiens(human)
    Product advanced glycosylation end product-specific receptor isoform 7 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL662884.11. On Jun 3, 2019 this sequence version replaced NM_172197.2. Transcript Variant: This variant (7, also known as RAGE_v16) uses alternate splice sites at several internal coding exons compared to variant 1. This results in a frame-shift and a shorter isoform (7, also known as hRAGEsec) with a distinct C-terminus compared to isoform 1. Sequence Note: This Refseq, containing two in-frame translation initiation codons (at nt 8-10 and nt 101-103), is annotated with a CDS starting from the downstream AUG (dAUG) because the AGE receptor encoded by this gene is a known type 1 transmembrane protein requiring signal peptide for its function, and a signal peptide of 22 aa is predicted for the dAUG initiated protein. Translation initiation from the upstream AUG (uAUG) will add an extra 31 aa to the N-terminus, and no signal peptide is predicted for the uAUG initiated protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ133822.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142363, SAMEA2147920 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGCTGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGG GAGGAGGCCC CTGGGACAGT
    GTGGCTCGTG TCCTTCCCAA CGGCTCCCTC TTCCTTCCGG CTGTCGGGAT CCAGGATGAG
    GGGATTTTCC GGTGCCAGGC AATGAACAGG AATGGAAAGG AGACCAAGTC CAACTACCGA
    GTCCGTGTCT ACCAGATTCC TGGGAAGCCA GAAATTGTAG ATTCTGCCTC TGAACTCACG
    GCTGGTGTTC CCAATAAGGT GGGGACATGT GTGTCAGAGG GAAGCTACCC TGCAGGGACT
    CTTAGCTGGC ACTTGGATGG GAAGCCCCTG GTGCCTAATG AGAAGGGAGT ATCTGTGAAG
    GAACAGACCA GGAGACACCC TGAGACAGGG CTCTTCACAC TGCAGTCGGA GCTAATGGTG
    ACCCCAGCCC GGGGAGGAGA TCCCCGTCCC ACCTTCTCCT GTAGCTTCAG CCCAGGCCTT
    CCCCGACACC GGGCCTTGCG CACAGCCCCC ATCCAGCCCC GTGTCTGGGA GCCTGTGCCT
    CTGGAGGAGG TCCAATTGGT GGTGGAGCCA GAAGGTGGAG CAGTAGCTCC TGGTGGAACC
    GTAACCCTGA CCTGTGAAGT CCCTGCCCAG CCCTCTCCTC AAATCCACTG GATGAAGGAT
    GTGAGTGACC TGGAGAGAGG GGCTGGGAGA ACCAGGCGAG GAGGGGCCAA CTGCAGGCTC
    TGTGGGAGGA TCAGGGCTGG GAACTCTAGC CCTGGCCCTG GGGATCCTGG GAGGCCTGGG
    GACAGCCGCC CTGCTCATTG GGGTCATCTT GTGGCAAAGG CGGCAACGCC GAGGAGAGGA
    GAGGAAGGCC CCAGAAAACC AGGAGGAAGA GGAGGAGCGT GCAGAACTGA ATCAGTCGGA
    GGAACCTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_751947.1
    CDS32..1060
    Translation

    Target ORF information:

    RefSeq Version NM_172197.3
    Organism Homo sapiens(human)
    Definition Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 7, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_172197.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGCTGCCG GAACAGCAGT TGGAGCCTGG GTGCTGGTCC TCAGTCTGTG GGGGGCAGTA 
    GTAGGTGCTC AAAACATCAC AGCCCGGATT GGCGAGCCAC TGGTGCTGAA GTGTAAGGGG
    GCCCCCAAGA AACCACCCCA GCGGCTGGAA TGGAAACTGG GAGGAGGCCC CTGGGACAGT
    GTGGCTCGTG TCCTTCCCAA CGGCTCCCTC TTCCTTCCGG CTGTCGGGAT CCAGGATGAG
    GGGATTTTCC GGTGCCAGGC AATGAACAGG AATGGAAAGG AGACCAAGTC CAACTACCGA
    GTCCGTGTCT ACCAGATTCC TGGGAAGCCA GAAATTGTAG ATTCTGCCTC TGAACTCACG
    GCTGGTGTTC CCAATAAGGT GGGGACATGT GTGTCAGAGG GAAGCTACCC TGCAGGGACT
    CTTAGCTGGC ACTTGGATGG GAAGCCCCTG GTGCCTAATG AGAAGGGAGT ATCTGTGAAG
    GAACAGACCA GGAGACACCC TGAGACAGGG CTCTTCACAC TGCAGTCGGA GCTAATGGTG
    ACCCCAGCCC GGGGAGGAGA TCCCCGTCCC ACCTTCTCCT GTAGCTTCAG CCCAGGCCTT
    CCCCGACACC GGGCCTTGCG CACAGCCCCC ATCCAGCCCC GTGTCTGGGA GCCTGTGCCT
    CTGGAGGAGG TCCAATTGGT GGTGGAGCCA GAAGGTGGAG CAGTAGCTCC TGGTGGAACC
    GTAACCCTGA CCTGTGAAGT CCCTGCCCAG CCCTCTCCTC AAATCCACTG GATGAAGGAT
    GTGAGTGACC TGGAGAGAGG GGCTGGGAGA ACCAGGCGAG GAGGGGCCAA CTGCAGGCTC
    TGTGGGAGGA TCAGGGCTGG GAACTCTAGC CCTGGCCCTG GGGATCCTGG GAGGCCTGGG
    GACAGCCGCC CTGCTCATTG GGGTCATCTT GTGGCAAAGG CGGCAACGCC GAGGAGAGGA
    GAGGAAGGCC CCAGAAAACC AGGAGGAAGA GGAGGAGCGT GCAGAACTGA ATCAGTCGGA
    GGAACCTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu96333
    Clone ID Related Accession (Same CDS sequence) XM_017010328.1 , XM_017010328.2
    Accession Version XM_017010328.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1119bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2016-06-05
    Organism Homo sapiens(human)
    Product advanced glycosylation end product-specific receptor isoform X1
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGGGGGCTG GAGAGAGGGT GCAGGCCCCA CCTAGGGCGG AGGCCACAGC AGGGAGAGGG 
    GCAGACAGAG CCAGGACCCT GGAAGGAAGC AGGATGGCTG CCGGAACAGC AGTTGGAGCC
    TGGGTGCTGG TCCTCAGTCT GTGGGGGGCA GTAGTAGGTG CTCAAAACAT CACAGCCCGG
    ATTGGCGAGC CACTGGTGCT GAAGTGTAAG GGGGCCCCCA AGAAACCACC CCAGCGGCTG
    GAATGGAAAC TGAACACAGG CCGGACAGAA GCTTGGAAGG TCCTGTCTCC CCAGGGAGGA
    GGCCCCTGGG ACAGTGTGGC TCGTGTCCTT CCCAACGGCT CCCTCTTCCT TCCGGCTGTC
    GGGATCCAGG ATGAGGGGAT TTTCCGGTGC CAGGCAATGA ACAGGAATGG AAAGGAGACC
    AAGTCCAACT ACCGAGTCCG TGTCTACCAG ATTCCTGGGA AGCCAGAAAT TGTAGATTCT
    GCCTCTGAAC TCACGGCTGG TGTTCCCAAT AAGGTAGTGG AAGAAAGCAG GAGAAGTAGA
    AAACGGCCCT GTGAACAGGA GGTGGGGACA TGTGTGTCAG AGGGAAGCTA CCCTGCAGGG
    ACTCTTAGCT GGCACTTGGA TGGGAAGCCC CTGGTGCCTA ATGAGAAGGG AGTATCTGTG
    AAGGAACAGA CCAGGAGACA CCCTGAGACA GGGCTCTTCA CACTGCAGTC GGAGCTAATG
    GTGACCCCAG CCCGGGGAGG AGATCCCCGT CCCACCTTCT CCTGTAGCTT CAGCCCAGGC
    CTTCCCCGAC ACCGGGCCTT GCGCACAGCC CCCATCCAGC CCCGTGTCTG GGAGCCTGTG
    CCTCTGGAGG AGGTCCAATT GGTGGTGGAG CCAGAAGGTG GAGCAGTAGC TCCTGGTGGA
    ACCGTAACCC TGACCTGTGA AGTCCCTGCC CAGCCCTCTC CTCAAATCCA CTGGATGAAG
    GATAACCAGG CGAGGAGGGG CCAACTGCAG GTGAGGGGTT TGATAAAGTC AGGGAAGCAG
    AAGATAGCCC CCAACACATG TGACTGGGGG GATGGTCAAC AAGAAAGGAA TGGAAGGCCC
    CAGAAAACCA GGAGGAAGAG GAGGAGCGTG CAGAACTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016865817.1
    CDS933..2051
    Translation

    Target ORF information:

    RefSeq Version XM_017010328.1
    Organism Homo sapiens(human)
    Definition Homo sapiens advanced glycosylation end product-specific receptor (AGER), transcript variant X1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017010328.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGGGGGCTG GAGAGAGGGT GCAGGCCCCA CCTAGGGCGG AGGCCACAGC AGGGAGAGGG 
    GCAGACAGAG CCAGGACCCT GGAAGGAAGC AGGATGGCTG CCGGAACAGC AGTTGGAGCC
    TGGGTGCTGG TCCTCAGTCT GTGGGGGGCA GTAGTAGGTG CTCAAAACAT CACAGCCCGG
    ATTGGCGAGC CACTGGTGCT GAAGTGTAAG GGGGCCCCCA AGAAACCACC CCAGCGGCTG
    GAATGGAAAC TGAACACAGG CCGGACAGAA GCTTGGAAGG TCCTGTCTCC CCAGGGAGGA
    GGCCCCTGGG ACAGTGTGGC TCGTGTCCTT CCCAACGGCT CCCTCTTCCT TCCGGCTGTC
    GGGATCCAGG ATGAGGGGAT TTTCCGGTGC CAGGCAATGA ACAGGAATGG AAAGGAGACC
    AAGTCCAACT ACCGAGTCCG TGTCTACCAG ATTCCTGGGA AGCCAGAAAT TGTAGATTCT
    GCCTCTGAAC TCACGGCTGG TGTTCCCAAT AAGGTAGTGG AAGAAAGCAG GAGAAGTAGA
    AAACGGCCCT GTGAACAGGA GGTGGGGACA TGTGTGTCAG AGGGAAGCTA CCCTGCAGGG
    ACTCTTAGCT GGCACTTGGA TGGGAAGCCC CTGGTGCCTA ATGAGAAGGG AGTATCTGTG
    AAGGAACAGA CCAGGAGACA CCCTGAGACA GGGCTCTTCA CACTGCAGTC GGAGCTAATG
    GTGACCCCAG CCCGGGGAGG AGATCCCCGT CCCACCTTCT CCTGTAGCTT CAGCCCAGGC
    CTTCCCCGAC ACCGGGCCTT GCGCACAGCC CCCATCCAGC CCCGTGTCTG GGAGCCTGTG
    CCTCTGGAGG AGGTCCAATT GGTGGTGGAG CCAGAAGGTG GAGCAGTAGC TCCTGGTGGA
    ACCGTAACCC TGACCTGTGA AGTCCCTGCC CAGCCCTCTC CTCAAATCCA CTGGATGAAG
    GATAACCAGG CGAGGAGGGG CCAACTGCAG GTGAGGGGTT TGATAAAGTC AGGGAAGCAG
    AAGATAGCCC CCAACACATG TGACTGGGGG GATGGTCAAC AAGAAAGGAA TGGAAGGCCC
    CAGAAAACCA GGAGGAAGAG GAGGAGCGTG CAGAACTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu96333
    Clone ID Related Accession (Same CDS sequence) XM_017010328.1 , XM_017010328.2
    Accession Version XM_017010328.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1119bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product advanced glycosylation end product-specific receptor isoform X1
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017010328.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGGGGGCTG GAGAGAGGGT GCAGGCCCCA CCTAGGGCGG AGGCCACAGC AGGGAGAGGG 
    GCAGACAGAG CCAGGACCCT GGAAGGAAGC AGGATGGCTG CCGGAACAGC AGTTGGAGCC
    TGGGTGCTGG TCCTCAGTCT GTGGGGGGCA GTAGTAGGTG CTCAAAACAT CACAGCCCGG
    ATTGGCGAGC CACTGGTGCT GAAGTGTAAG GGGGCCCCCA AGAAACCACC CCAGCGGCTG
    GAATGGAAAC TGAACACAGG CCGGACAGAA GCTTGGAAGG TCCTGTCTCC CCAGGGAGGA
    GGCCCCTGGG ACAGTGTGGC TCGTGTCCTT CCCAACGGCT CCCTCTTCCT TCCGGCTGTC
    GGGATCCAGG ATGAGGGGAT TTTCCGGTGC CAGGCAATGA ACAGGAATGG AAAGGAGACC
    AAGTCCAACT ACCGAGTCCG TGTCTACCAG ATTCCTGGGA AGCCAGAAAT TGTAGATTCT
    GCCTCTGAAC TCACGGCTGG TGTTCCCAAT AAGGTAGTGG AAGAAAGCAG GAGAAGTAGA
    AAACGGCCCT GTGAACAGGA GGTGGGGACA TGTGTGTCAG AGGGAAGCTA CCCTGCAGGG
    ACTCTTAGCT GGCACTTGGA TGGGAAGCCC CTGGTGCCTA ATGAGAAGGG AGTATCTGTG
    AAGGAACAGA CCAGGAGACA CCCTGAGACA GGGCTCTTCA CACTGCAGTC GGAGCTAATG
    GTGACCCCAG CCCGGGGAGG AGATCCCCGT CCCACCTTCT CCTGTAGCTT CAGCCCAGGC
    CTTCCCCGAC ACCGGGCCTT GCGCACAGCC CCCATCCAGC CCCGTGTCTG GGAGCCTGTG
    CCTCTGGAGG AGGTCCAATT GGTGGTGGAG CCAGAAGGTG GAGCAGTAGC TCCTGGTGGA
    ACCGTAACCC TGACCTGTGA AGTCCCTGCC CAGCCCTCTC CTCAAATCCA CTGGATGAAG
    GATAACCAGG CGAGGAGGGG CCAACTGCAG GTGAGGGGTT TGATAAAGTC AGGGAAGCAG
    AAGATAGCCC CCAACACATG TGACTGGGGG GATGGTCAAC AAGAAAGGAA TGGAAGGCCC
    CAGAAAACCA GGAGGAAGAG GAGGAGCGTG CAGAACTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016865817.1
    CDS66..1184
    Translation

    Target ORF information:

    RefSeq Version XM_017010328.2
    Organism Homo sapiens(human)
    Definition Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant X1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017010328.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGGGGGCTG GAGAGAGGGT GCAGGCCCCA CCTAGGGCGG AGGCCACAGC AGGGAGAGGG 
    GCAGACAGAG CCAGGACCCT GGAAGGAAGC AGGATGGCTG CCGGAACAGC AGTTGGAGCC
    TGGGTGCTGG TCCTCAGTCT GTGGGGGGCA GTAGTAGGTG CTCAAAACAT CACAGCCCGG
    ATTGGCGAGC CACTGGTGCT GAAGTGTAAG GGGGCCCCCA AGAAACCACC CCAGCGGCTG
    GAATGGAAAC TGAACACAGG CCGGACAGAA GCTTGGAAGG TCCTGTCTCC CCAGGGAGGA
    GGCCCCTGGG ACAGTGTGGC TCGTGTCCTT CCCAACGGCT CCCTCTTCCT TCCGGCTGTC
    GGGATCCAGG ATGAGGGGAT TTTCCGGTGC CAGGCAATGA ACAGGAATGG AAAGGAGACC
    AAGTCCAACT ACCGAGTCCG TGTCTACCAG ATTCCTGGGA AGCCAGAAAT TGTAGATTCT
    GCCTCTGAAC TCACGGCTGG TGTTCCCAAT AAGGTAGTGG AAGAAAGCAG GAGAAGTAGA
    AAACGGCCCT GTGAACAGGA GGTGGGGACA TGTGTGTCAG AGGGAAGCTA CCCTGCAGGG
    ACTCTTAGCT GGCACTTGGA TGGGAAGCCC CTGGTGCCTA ATGAGAAGGG AGTATCTGTG
    AAGGAACAGA CCAGGAGACA CCCTGAGACA GGGCTCTTCA CACTGCAGTC GGAGCTAATG
    GTGACCCCAG CCCGGGGAGG AGATCCCCGT CCCACCTTCT CCTGTAGCTT CAGCCCAGGC
    CTTCCCCGAC ACCGGGCCTT GCGCACAGCC CCCATCCAGC CCCGTGTCTG GGAGCCTGTG
    CCTCTGGAGG AGGTCCAATT GGTGGTGGAG CCAGAAGGTG GAGCAGTAGC TCCTGGTGGA
    ACCGTAACCC TGACCTGTGA AGTCCCTGCC CAGCCCTCTC CTCAAATCCA CTGGATGAAG
    GATAACCAGG CGAGGAGGGG CCAACTGCAG GTGAGGGGTT TGATAAAGTC AGGGAAGCAG
    AAGATAGCCC CCAACACATG TGACTGGGGG GATGGTCAAC AAGAAAGGAA TGGAAGGCCC
    CAGAAAACCA GGAGGAAGAG GAGGAGCGTG CAGAACTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.