NUDT10 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NUDT10
Entrez Gene ID	170685
Full Name	nudix hydrolase 10
Synonyms	APS2,DIPP3-alpha,DIPP3a
General protein information	Preferred Names nudix hydrolase 10 Names diphosphoinositol polyphosphate phosphohydrolase 3-alpha diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-alpha diadenosine hexaphosphate hydrolase (AMP-forming) nucleoside diphosphate-linked moiety X motif 10 nudix (nucleoside diphosphate linked moiety X)-type motif 10 nudix motif 10
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xp11.22
Summary	This gene is a member of the nudix (nucleoside diphosphate linked moiety X)-type motif containing family. The encoded protein is a phosphohydrolase and may regulate the turnover of diphosphoinositol polyphosphates. The turnover of these high-energy diphosphoinositol polyphosphates represents a molecular switching activity with important regulatory consequences. Molecular switching by diphosphoinositol polyphosphates may contribute to the regulation of intracellular trafficking. In some populations putative prostate cancer susceptibility alleles have been identified for this gene. Alternatively spliced transcript variants, which differ only in the 5' UTR, have been found for this gene. [provided by RefSeq, Feb 2015].
Disorder MIM:	300527

mRNA and Protein(s)

mRNA	Protein	Name
NM_001304963.2	NP_001291892.1	diphosphoinositol polyphosphate phosphohydrolase 3-alpha
NM_001304963.1	NP_001291892.1	diphosphoinositol polyphosphate phosphohydrolase 3-alpha
NM_153183.3	NP_694853.1	diphosphoinositol polyphosphate phosphohydrolase 3-alpha

Pathways from BioSystems

Homologies

Homo sapiens (human)	NUDT10	NP_694853.1
	LOC695921	XP_001084212.2

Gene Ontology
Bibliography

Related articles in PubMed

Validation of genome-wide prostate cancer associations in men of African descent.
Chang BL, Spangler E, Gallagher S, Haiman CA, Henderson B, Isaacs W, Benford ML, Kidd LR, Cooney K, Strom S, Ingles SA, Stern MC, Corral R, Joshi AD, Xu J, Giri VN, Rybicki B, Neslund-Dudas C, Kibel AS, Thompson IM, Leach RJ, Ostrander EA, Stanford JL, Witte J, Casey G, Eeles R, Hsing AW, Chanock S, Hu JJ, John EM, Park J, Stefflova K, Zeigler-Johnson C, Rebbeck TR
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology20(1)23-32(2011 Jan)

Prostate cancer risk-associated variants reported from genome-wide association studies: meta-analysis and their contribution to genetic Variation.
Kim ST, Cheng Y, Hsu FC, Jin T, Kader AK, Zheng SL, Isaacs WB, Xu J, Sun J
The Prostate70(16)1729-38(2010 Dec)

Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer.
Gudmundsson J, Sulem P, Rafnar T, Bergthorsson JT, Manolescu A, Gudbjartsson D, Agnarsson BA, Sigurdsson A, Benediktsdottir KR, Blondal T, Jakobsdottir M, Stacey SN, Kostic J, Kristinsson KT, Birgisdottir B, Ghosh S, Magnusdottir DN, Thorlacius S, Thorleifsson G, Zheng SL, Sun J, Chang BL, Elmore JB, Breyer JP, McReynolds KM, Bradley KM, Yaspan BL, Wiklund F, Stattin P, Lindstr?m S, Adami HO, McDonnell SK, Schaid DJ, Cunningham JM, Wang L, Cerhan JR, St Sauver JL, Isaacs SD, Wiley KE, Partin AW, Walsh PC, Polo S, Ruiz-Echarri M, Navarrete S, Fuertes F, Saez B, Godino J, Weijerman PC, Swinkels DW, Aben KK, Witjes JA, Suarez BK, Helfand BT, Frigge ML, Kristjansson K, Ober C, Jonsson E, Einarsson GV, Xu J, Gronberg H, Smith JR, Thibodeau SN, Isaacs WB, Catalona WJ, Mayordomo JI, Kiemeney LA, Barkardottir RB, Gulcher JR, Thorsteinsdottir U, Kong A, Stefansson K
Nature genetics40(3)281-3(2008 Mar)

Multiple newly identified loci associated with prostate cancer susceptibility.
Eeles RA, Kote-Jarai Z, Giles GG, Olama AA, Guy M, Jugurnauth SK, Mulholland S, Leongamornlert DA, Edwards SM, Morrison J, Field HI, Southey MC, Severi G, Donovan JL, Hamdy FC, Dearnaley DP, Muir KR, Smith C, Bagnato M, Ardern-Jones AT, Hall AL, O'Brien LT, Gehr-Swain BN, Wilkinson RA, Cox A, Lewis S, Brown PM, Jhavar SG, Tymrakiewicz M, Lophatananon A, Bryant SL, , , , Horwich A, Huddart RA, Khoo VS, Parker CC, Woodhouse CJ, Thompson A, Christmas T, Ogden C, Fisher C, Jamieson C, Cooper CS, English DR, Hopper JL, Neal DE, Easton DF
Nature genetics40(3)316-21(2008 Mar)

Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate.
Fisher DI, Safrany ST, Strike P, McLennan AG, Cartwright JL
The Journal of biological chemistry277(49)47313-7(2002 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: Validation of genome-wide prostate cancer associations in men of African descent.

Meta-analysis of gene-disease association. (HuGE Navigator)
Title: Prostate cancer risk-associated variants reported from genome-wide association studies: meta-analysis and their contribution to genetic Variation.

The NUDT10 gene, located on chromosome X, is preferentially expressed in the testis
Title: An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase.

Cloning and characterisation of NUDT10 as a diadenosine polyphosphate-metabolising Nudix hydrolase.
Title: Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases.

The following NUDT10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NUDT10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30810	NM_001304963.2 Latest version!	Homo sapiens nudix hydrolase 10 (NUDT10), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu30810	NM_153183.3 Latest version!	Homo sapiens nudix hydrolase 10 (NUDT10), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu30810	NM_001304963.1	Homo sapiens nudix hydrolase 10 (NUDT10), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NUDT10 ( NM_001304963.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001291892.1 Homo sapiens nudix hydrolase 10 (NUDT10), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30810
Clone ID Related Accession (Same CDS sequence)	NM_001304963.2 , NM_001304963.1 , NM_153183.3
Accession Version	NM_001304963.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 495bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	diphosphoinositol polyphosphate phosphohydrolase 3-alpha
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX449265.2, BC050700.1, CN399689.1 and BC049383.1. On Nov 22, 2018 this sequence version replaced NM_001304963.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.746620.1, SRR3476690.1132745.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000356450.3/ ENSP00000348831.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGTGCA AACCCAACCA GACACGGACC TACGACCCCG AGGGGTTCAA GAAGCGGGCG 
GCGTGCCTGT GCTTCCGGAG CGAGCGCGAG GACGAGGTCC TGTTAGTGAG TAGCAGCCGG 
TACCCGGACC GCTGGATCGT GCCGGGCGGG GGCATGGAGC CCGAGGAGGA GCCGGGCGGT 
GCGGCGGTCC GAGAGGTGTA CGAAGAGGCG GGAGTCAAGG GGAAGTTAGG CCGGCTCCTG 
GGCGTCTTCG AACAGAACCA GGACCCCAAG CACAGAACGT ACGTGTATGT ACTGACTGTC 
ACGGAGCTGC TGGAGGATTG GGAAGATTCG GTTAGCATTG GGAGGAAGCG AGAGTGGTTC 
AAAGTCGAAG ATGCCATCAA GGTTCTCCAG TGCCACAAGC CCGTGCACGC CGAATATCTG 
GAGAAACTAA AGCTGGGCGG TTCCCCAACC AATGGAAACT CCATGGCCCC ATCCTCGCCA 
GATAGCGATC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001291892.1
CDS	145..639
Translation	MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGGAAVREVYEEAGVKGKLGRLLGVFEQNQDPKHRTYVYVLTVTELLEDWEDSVSIGRKREWFKVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP

Target ORF information:

RefSeq Version	NM_001304963.2
Organism	Homo sapiens(human)
Definition	Homo sapiens nudix hydrolase 10 (NUDT10), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001304963.2

ORF Insert Sequence:

ATGAAGTGCA AACCCAACCA GACACGGACC TACGACCCCG AGGGGTTCAA GAAGCGGGCG 
GCGTGCCTGT GCTTCCGGAG CGAGCGCGAG GACGAGGTCC TGTTAGTGAG TAGCAGCCGG 
TACCCGGACC GCTGGATCGT GCCGGGCGGG GGCATGGAGC CCGAGGAGGA GCCGGGCGGT 
GCGGCGGTCC GAGAGGTGTA CGAAGAGGCG GGAGTCAAGG GGAAGTTAGG CCGGCTCCTG 
GGCGTCTTCG AACAGAACCA GGACCCCAAG CACAGAACGT ACGTGTATGT ACTGACTGTC 
ACGGAGCTGC TGGAGGATTG GGAAGATTCG GTTAGCATTG GGAGGAAGCG AGAGTGGTTC 
AAAGTCGAAG ATGCCATCAA GGTTCTCCAG TGCCACAAGC CCGTGCACGC CGAATATCTG 
GAGAAACTAA AGCTGGGCGG TTCCCCAACC AATGGAAACT CCATGGCCCC ATCCTCGCCA 
GATAGCGATC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NUDT10 ( NM_001304963.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001291892.1 Homo sapiens nudix hydrolase 10 (NUDT10), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30810
Clone ID Related Accession (Same CDS sequence)	NM_001304963.2 , NM_001304963.1 , NM_153183.3
Accession Version	NM_001304963.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 495bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	diphosphoinositol polyphosphate phosphohydrolase 3-alpha
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX449265.2, BC050700.1, CN399689.1 and BC049383.1. On Feb 12, 2015 this sequence version replaced XM_005262042.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BC050700.1, SRR1660803.169627.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGTGCA AACCCAACCA GACACGGACC TACGACCCCG AGGGGTTCAA GAAGCGGGCG 
GCGTGCCTGT GCTTCCGGAG CGAGCGCGAG GACGAGGTCC TGTTAGTGAG TAGCAGCCGG 
TACCCGGACC GCTGGATCGT GCCGGGCGGG GGCATGGAGC CCGAGGAGGA GCCGGGCGGT 
GCGGCGGTCC GAGAGGTGTA CGAAGAGGCG GGAGTCAAGG GGAAGTTAGG CCGGCTCCTG 
GGCGTCTTCG AACAGAACCA GGACCCCAAG CACAGAACGT ACGTGTATGT ACTGACTGTC 
ACGGAGCTGC TGGAGGATTG GGAAGATTCG GTTAGCATTG GGAGGAAGCG AGAGTGGTTC 
AAAGTCGAAG ATGCCATCAA GGTTCTCCAG TGCCACAAGC CCGTGCACGC CGAATATCTG 
GAGAAACTAA AGCTGGGCGG TTCCCCAACC AATGGAAACT CCATGGCCCC ATCCTCGCCA 
GATAGCGATC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001291892.1
CDS	158..652
Translation	MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGGAAVREVYEEAGVKGKLGRLLGVFEQNQDPKHRTYVYVLTVTELLEDWEDSVSIGRKREWFKVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP

Target ORF information:

RefSeq Version	NM_001304963.1
Organism	Homo sapiens(human)
Definition	Homo sapiens nudix hydrolase 10 (NUDT10), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001304963.1

ORF Insert Sequence:

ATGAAGTGCA AACCCAACCA GACACGGACC TACGACCCCG AGGGGTTCAA GAAGCGGGCG 
GCGTGCCTGT GCTTCCGGAG CGAGCGCGAG GACGAGGTCC TGTTAGTGAG TAGCAGCCGG 
TACCCGGACC GCTGGATCGT GCCGGGCGGG GGCATGGAGC CCGAGGAGGA GCCGGGCGGT 
GCGGCGGTCC GAGAGGTGTA CGAAGAGGCG GGAGTCAAGG GGAAGTTAGG CCGGCTCCTG 
GGCGTCTTCG AACAGAACCA GGACCCCAAG CACAGAACGT ACGTGTATGT ACTGACTGTC 
ACGGAGCTGC TGGAGGATTG GGAAGATTCG GTTAGCATTG GGAGGAAGCG AGAGTGGTTC 
AAAGTCGAAG ATGCCATCAA GGTTCTCCAG TGCCACAAGC CCGTGCACGC CGAATATCTG 
GAGAAACTAA AGCTGGGCGG TTCCCCAACC AATGGAAACT CCATGGCCCC ATCCTCGCCA 
GATAGCGATC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NUDT10 ( NM_153183.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_694853.1 Homo sapiens nudix hydrolase 10 (NUDT10), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30810
Clone ID Related Accession (Same CDS sequence)	NM_001304963.2 , NM_001304963.1 , NM_153183.3
Accession Version	NM_153183.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 495bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	diphosphoinositol polyphosphate phosphohydrolase 3-alpha
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF469196.1, AC233976.3 and AK291952.1. On Feb 12, 2015 this sequence version replaced NM_153183.2. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AF469196.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGTGCA AACCCAACCA GACACGGACC TACGACCCCG AGGGGTTCAA GAAGCGGGCG 
GCGTGCCTGT GCTTCCGGAG CGAGCGCGAG GACGAGGTCC TGTTAGTGAG TAGCAGCCGG 
TACCCGGACC GCTGGATCGT GCCGGGCGGG GGCATGGAGC CCGAGGAGGA GCCGGGCGGT 
GCGGCGGTCC GAGAGGTGTA CGAAGAGGCG GGAGTCAAGG GGAAGTTAGG CCGGCTCCTG 
GGCGTCTTCG AACAGAACCA GGACCCCAAG CACAGAACGT ACGTGTATGT ACTGACTGTC 
ACGGAGCTGC TGGAGGATTG GGAAGATTCG GTTAGCATTG GGAGGAAGCG AGAGTGGTTC 
AAAGTCGAAG ATGCCATCAA GGTTCTCCAG TGCCACAAGC CCGTGCACGC CGAATATCTG 
GAGAAACTAA AGCTGGGCGG TTCCCCAACC AATGGAAACT CCATGGCCCC ATCCTCGCCA 
GATAGCGATC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_694853.1
CDS	221..715
Translation	MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGGAAVREVYEEAGVKGKLGRLLGVFEQNQDPKHRTYVYVLTVTELLEDWEDSVSIGRKREWFKVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP

Target ORF information:

RefSeq Version	NM_153183.3
Organism	Homo sapiens(human)
Definition	Homo sapiens nudix hydrolase 10 (NUDT10), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153183.3

ORF Insert Sequence:

ATGAAGTGCA AACCCAACCA GACACGGACC TACGACCCCG AGGGGTTCAA GAAGCGGGCG 
GCGTGCCTGT GCTTCCGGAG CGAGCGCGAG GACGAGGTCC TGTTAGTGAG TAGCAGCCGG 
TACCCGGACC GCTGGATCGT GCCGGGCGGG GGCATGGAGC CCGAGGAGGA GCCGGGCGGT 
GCGGCGGTCC GAGAGGTGTA CGAAGAGGCG GGAGTCAAGG GGAAGTTAGG CCGGCTCCTG 
GGCGTCTTCG AACAGAACCA GGACCCCAAG CACAGAACGT ACGTGTATGT ACTGACTGTC 
ACGGAGCTGC TGGAGGATTG GGAAGATTCG GTTAGCATTG GGAGGAAGCG AGAGTGGTTC 
AAAGTCGAAG ATGCCATCAA GGTTCTCCAG TGCCACAAGC CCGTGCACGC CGAATATCTG 
GAGAAACTAA AGCTGGGCGG TTCCCCAACC AATGGAAACT CCATGGCCCC ATCCTCGCCA 
GATAGCGATC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Validation of genome-wide prostate cancer associations in men of African descent.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology20(1)23-32(2011 Jan)
Chang BL,Spangler E,Gallagher S,Haiman CA,Henderson B,Isaacs W,Benford ML,Kidd LR,Cooney K,Strom S,Ingles SA,Stern MC,Corral R,Joshi AD,Xu J,Giri VN,Rybicki B,Neslund-Dudas C,Kibel AS,Thompson IM,Leach RJ,Ostrander EA,Stanford JL,Witte J,Casey G,Eeles R,Hsing AW,Chanock S,Hu JJ,John EM,Park J,Stefflova K,Zeigler-Johnson C,Rebbeck TR

Prostate cancer risk-associated variants reported from genome-wide association studies: meta-analysis and their contribution to genetic Variation.
The Prostate70(16)1729-38(2010 Dec)
Kim ST,Cheng Y,Hsu FC,Jin T,Kader AK,Zheng SL,Isaacs WB,Xu J,Sun J

Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer.
Nature genetics40(3)281-3(2008 Mar)
Gudmundsson J,Sulem P,Rafnar T,Bergthorsson JT,Manolescu A,Gudbjartsson D,Agnarsson BA,Sigurdsson A,Benediktsdottir KR,Blondal T,Jakobsdottir M,Stacey SN,Kostic J,Kristinsson KT,Birgisdottir B,Ghosh S,Magnusdottir DN,Thorlacius S,Thorleifsson G,Zheng SL,Sun J,Chang BL,Elmore JB,Breyer JP,McReynolds KM,Bradley KM,Yaspan BL,Wiklund F,Stattin P,Lindstr?m S,Adami HO,McDonnell SK,Schaid DJ,Cunningham JM,Wang L,Cerhan JR,St Sauver JL,Isaacs SD,Wiley KE,Partin AW,Walsh PC,Polo S,Ruiz-Echarri M,Navarrete S,Fuertes F,Saez B,Godino J,Weijerman PC,Swinkels DW,Aben KK,Witjes JA,Suarez BK,Helfand BT,Frigge ML,Kristjansson K,Ober C,Jonsson E,Einarsson GV,Xu J,Gronberg H,Smith JR,Thibodeau SN,Isaacs WB,Catalona WJ,Mayordomo JI,Kiemeney LA,Barkardottir RB,Gulcher JR,Thorsteinsdottir U,Kong A,Stefansson K

Multiple newly identified loci associated with prostate cancer susceptibility.
Nature genetics40(3)316-21(2008 Mar)
Eeles RA,Kote-Jarai Z,Giles GG,Olama AA,Guy M,Jugurnauth SK,Mulholland S,Leongamornlert DA,Edwards SM,Morrison J,Field HI,Southey MC,Severi G,Donovan JL,Hamdy FC,Dearnaley DP,Muir KR,Smith C,Bagnato M,Ardern-Jones AT,Hall AL,O'Brien LT,Gehr-Swain BN,Wilkinson RA,Cox A,Lewis S,Brown PM,Jhavar SG,Tymrakiewicz M,Lophatananon A,Bryant SL,,,,Horwich A,Huddart RA,Khoo VS,Parker CC,Woodhouse CJ,Thompson A,Christmas T,Ogden C,Fisher C,Jamieson C,Cooper CS,English DR,Hopper JL,Neal DE,Easton DF

Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate.
The Journal of biological chemistry277(49)47313-7(2002 Dec)
Fisher DI,Safrany ST,Strike P,McLennan AG,Cartwright JL

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NUDT10 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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