GBP6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GBP6
Entrez Gene ID	163351
Full Name	guanylate binding protein family member 6
General protein information	Preferred Names guanylate binding protein family member 6 Names guanylate-binding protein 6 GBP-6 GTP-binding protein 6 guanine nucleotide-binding protein 6
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p22.2
Summary	Guanylate-binding proteins, such as GBP6, are induced by interferon and hydrolyze GTP to both GDP and GMP (Olszewski et al., 2006 [PubMed 16689661]).[supplied by OMIM, Dec 2008].
Disorder MIM:	612467

mRNA and Protein(s)

mRNA	Protein	Name
NM_001320257.1	NP_001307186.1	guanylate-binding protein 6 isoform 2
NM_198460.2	NP_940862.2	guanylate-binding protein 6 isoform 1
NM_198460.3	NP_940862.2	guanylate-binding protein 6 isoform 1
XM_011540835.3	XP_011539137.1	guanylate-binding protein 6 isoform X1
XM_011540835.2	XP_011539137.1	guanylate-binding protein 6 isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Gbp6	NP_919317.2
Mus musculus (house mouse)	Gbp9	NP_766365.1
Danio rerio (zebrafish)	gbp3	XP_005171472.1
	GBP6	XP_001086706.1
Bos taurus (cattle)	LOC526823	XP_003585927.1
Rattus norvegicus (Norway rat)	Mpa2l	XP_006250671.1
Danio rerio (zebrafish)	LOC100330518	XP_002660932.2
Xenopus tropicalis (tropical clawed frog)	gbp2	NP_001072267.1
Mus musculus (house mouse)	Gbp11	NP_001034736.2
Xenopus tropicalis (tropical clawed frog)	gbp1	NP_001016773.1
Xenopus tropicalis (tropical clawed frog)	LOC100489592	XP_002939179.2
Xenopus tropicalis (tropical clawed frog)	gbp4	XP_002939170.2
Pan troglodytes (chimpanzee)	GBP6	XP_001149964.1
Mus musculus (house mouse)	Gbp10	NP_001034735.2
Mus musculus (house mouse)	Gbp4	NP_001242934.1
Danio rerio (zebrafish)	gbp2	XP_699217.2
Homo sapiens (human)	GBP6	NP_940862.2
Canis lupus familiaris (dog)	GBP6	XP_547290.2
Bos taurus (cattle)	GBP7	XP_002686308.1
Danio rerio (zebrafish)	si:ch211-195h23.3	NP_001123874.1
Xenopus tropicalis (tropical clawed frog)	gbp6	NP_001120628.1
Xenopus tropicalis (tropical clawed frog)	gbp5	NP_001120244.2

Gene Ontology
Bibliography

Related articles in PubMed

New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes and immunity11(3)232-8(2010 Apr)

Lack of replication of genetic predictors for the rheumatoid arthritis response to anti-TNF treatments: a prospective case-only study.
Suarez-Gestal M, Perez-Pampin E, Calaza M, Gomez-Reino JJ, Gonzalez A
Arthritis research & therapy12(2)R72(2010)

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal of proteome research8(3)1304-14(2009 Mar)

In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters.
Olszewski MA, Gray J, Vestal DJ
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research26(5)328-52(2006 May)

Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.
Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S
EMBO reports1(3)287-92(2000 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: New genetic associations detected in a host response study to hepatitis B vaccine.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Lack of replication of genetic predictors for the rheumatoid arthritis response to anti-TNF treatments: a prospective case-only study.

The following GBP6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GBP6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu33076	NM_001320257.1 Latest version!	Homo sapiens guanylate binding protein family member 6 (GBP6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu08935	XM_011540835.3 Latest version!	Homo sapiens guanylate binding protein family member 6 (GBP6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu08935	NM_198460.3 Latest version!	Homo sapiens guanylate binding protein family member 6 (GBP6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu08935	NM_198460.2	Homo sapiens guanylate binding protein family member 6 (GBP6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu08935	XM_011540835.2	Homo sapiens guanylate binding protein family member 6 (GBP6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GBP6 ( NM_198460.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_940862.2 Homo sapiens guanylate binding protein family member 6 (GBP6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu08935
Clone ID Related Accession (Same CDS sequence)	NM_198460.2 , NM_198460.3 , XM_011540835.3 , XM_011540835.2
Accession Version	NM_198460.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1902bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-30
Organism	Homo sapiens(human)
Product	guanylate-binding protein 6 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA437660.1, DA447005.1, AK131356.1, AL691464.4 and AI199897.1. On Sep 26, 2007 this sequence version replaced NM_198460.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BX537949.1, AK131356.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145245, SAMEA2147975 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAATCTG GACCCAAAAT GTTGGCCCCC GTTTGCCTGG TGGAAAATAA CAATGAGCAG 
CTATTGGTGA ACCAGCAAGC TATACAGATT CTTGAAAAGA TTTCTCAGCC AGTGGTGGTG 
GTGGCCATTG TAGGACTGTA CCGTACAGGG AAATCCTACT TGATGAACCA TCTGGCAGGA 
CAGAATCATG GCTTCCCTCT GGGCTCCACG GTGCAGTCTG AAACCAAGGG CATCTGGATG 
TGGTGCGTGC CCCACCCATC CAAGCCAAAC CACACCCTGG TCCTTCTGGA CACCGAAGGT 
CTGGGCGATG TGGAAAAGGG TGACCCTAAG AATGACTCCT GGATCTTTGC CCTGGCTGTG 
CTCCTGTGCA GCACCTTTGT CTACAACAGC ATGAGCACCA TCAACCACCA GGCCCTGGAG 
CAGCTGCATT ATGTGACGGA GCTCACAGAA CTAATTAAGG CAAAGTCCTC CCCAAGGCCT 
GATGGAGTAG AAGATTCCAC AGAGTTTGTG AGTTTCTTCC CAGACTTTCT TTGGACAGTA 
CGGGATTTCA CTCTGGAGCT GAAGTTGAAC GGTCACCCTA TCACAGAAGA TGAATACCTG 
GAGAATGCCT TGAAGCTGAT TCAAGGCAAT AATCCCAGAG TTCAAACATC CAATTTTCCC 
AGGGAGTGCA TCAGGCGTTT CTTTCCAAAA CGGAAGTGTT TCGTCTTTGA CCGGCCAACA 
AATGACAAAG ACCTTCTAGC CAATATTGAG AAGGTGTCAG AAAAGCAACT GGATCCCAAA 
TTCCAGGAAC AAACAAACAT TTTCTGTTCT TACATCTTCA CTCATGCAAG AACCAAGACC 
CTCAGGGAGG GAATCACAGT CACTGGGAAT CGTCTGGGAA CTCTGGCAGT GACTTATGTA 
GAGGCCATCA ACAGTGGAGC AGTGCCTTGT CTGGAGAATG CAGTGATAAC TCTGGCCCAG 
CGTGAGAACT CAGCGGCCGT GCAGAGGGCA GCTGACTACT ACAGCCAGCA GATGGCCCAG 
CGAGTGAAGC TCCCCACAGA CACGCTCCAG GAGCTGCTGG ACATGCATGC GGCCTGTGAG 
AGGGAAGCCA TTGCAATCTT CATGGAGCAC TCCTTCAAGG ATGAAAATCA GGAATTCCAG 
AAGAAGTTCA TGGAAACCAC AATGAATAAG AAGGGGGATT TCTTGCTGCA GAATGAAGAG 
TCATCTGTTC AATACTGCCA GGCTAAACTC AATGAGCTCT CAAAGGGACT AATGGAAAGT 
ATCTCAGCAG GAAGTTTCTC TGTTCCTGGA GGGCACAAGC TCTACATGGA AACAAAGGAA 
AGGATTGAAC AGGACTATTG GCAAGTTCCC AGGAAAGGAG TAAAGGCAAA AGAGGTCTTC 
CAGAGGTTCC TGGAGTCACA GATGGTGATA GAGGAATCCA TCTTGCAGTC AGATAAAGCC 
CTCACTGATA GAGAGAAGGC AGTAGCAGTG GATCGGGCCA AGAAGGAGGC AGCTGAGAAG 
GAACAGGAAC TTTTAAAACA GAAATTACAG GAGCAGCAGC AACAGATGGA GGCTCAAGAT 
AAGAGTCGCA AGGAAAACAT AGCCCAACTG AAGGAGAAGC TGCAGATGGA GAGAGAACAC 
CTACTGAGAG AGCAGATTAT GATGTTGGAG CACACGCAGA AGGTCCAAAA TGATTGGCTT 
CATGAAGGAT TTAAGAAGAA GTATGAGGAG ATGAATGCAG AGATAAGTCA ATTTAAACGT 
ATGATTGATA CTACAAAAAA TGATGATACT CCCTGGATTG CACGAACCTT GGACAACCTT 
GCCGATGAGC TAACTGCAAT ATTGTCTGCT CCTGCTAAAT TAATTGGTCA TGGTGTCAAA 
GGTGTGAGCT CACTCTTTAA AAAGCATAAG CTCCCCTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_940862.2
CDS	275..2176
Translation	MESGPKMLAPVCLVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAGQNHGFPLGSTVQSETKGIWMWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTVRDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPTNDKDLLANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVTYVEAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIARTLDNLADELTAILSAPAKLIGHGVKGVSSLFKKHKLPF

Target ORF information:

RefSeq Version	NM_198460.2
Organism	Homo sapiens(human)
Definition	Homo sapiens guanylate binding protein family member 6 (GBP6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198460.2

ORF Insert Sequence:

ATGGAATCTG GACCCAAAAT GTTGGCCCCC GTTTGCCTGG TGGAAAATAA CAATGAGCAG 
CTATTGGTGA ACCAGCAAGC TATACAGATT CTTGAAAAGA TTTCTCAGCC AGTGGTGGTG 
GTGGCCATTG TAGGACTGTA CCGTACAGGG AAATCCTACT TGATGAACCA TCTGGCAGGA 
CAGAATCATG GCTTCCCTCT GGGCTCCACG GTGCAGTCTG AAACCAAGGG CATCTGGATG 
TGGTGCGTGC CCCACCCATC CAAGCCAAAC CACACCCTGG TCCTTCTGGA CACCGAAGGT 
CTGGGCGATG TGGAAAAGGG TGACCCTAAG AATGACTCCT GGATCTTTGC CCTGGCTGTG 
CTCCTGTGCA GCACCTTTGT CTACAACAGC ATGAGCACCA TCAACCACCA GGCCCTGGAG 
CAGCTGCATT ATGTGACGGA GCTCACAGAA CTAATTAAGG CAAAGTCCTC CCCAAGGCCT 
GATGGAGTAG AAGATTCCAC AGAGTTTGTG AGTTTCTTCC CAGACTTTCT TTGGACAGTA 
CGGGATTTCA CTCTGGAGCT GAAGTTGAAC GGTCACCCTA TCACAGAAGA TGAATACCTG 
GAGAATGCCT TGAAGCTGAT TCAAGGCAAT AATCCCAGAG TTCAAACATC CAATTTTCCC 
AGGGAGTGCA TCAGGCGTTT CTTTCCAAAA CGGAAGTGTT TCGTCTTTGA CCGGCCAACA 
AATGACAAAG ACCTTCTAGC CAATATTGAG AAGGTGTCAG AAAAGCAACT GGATCCCAAA 
TTCCAGGAAC AAACAAACAT TTTCTGTTCT TACATCTTCA CTCATGCAAG AACCAAGACC 
CTCAGGGAGG GAATCACAGT CACTGGGAAT CGTCTGGGAA CTCTGGCAGT GACTTATGTA 
GAGGCCATCA ACAGTGGAGC AGTGCCTTGT CTGGAGAATG CAGTGATAAC TCTGGCCCAG 
CGTGAGAACT CAGCGGCCGT GCAGAGGGCA GCTGACTACT ACAGCCAGCA GATGGCCCAG 
CGAGTGAAGC TCCCCACAGA CACGCTCCAG GAGCTGCTGG ACATGCATGC GGCCTGTGAG 
AGGGAAGCCA TTGCAATCTT CATGGAGCAC TCCTTCAAGG ATGAAAATCA GGAATTCCAG 
AAGAAGTTCA TGGAAACCAC AATGAATAAG AAGGGGGATT TCTTGCTGCA GAATGAAGAG 
TCATCTGTTC AATACTGCCA GGCTAAACTC AATGAGCTCT CAAAGGGACT AATGGAAAGT 
ATCTCAGCAG GAAGTTTCTC TGTTCCTGGA GGGCACAAGC TCTACATGGA AACAAAGGAA 
AGGATTGAAC AGGACTATTG GCAAGTTCCC AGGAAAGGAG TAAAGGCAAA AGAGGTCTTC 
CAGAGGTTCC TGGAGTCACA GATGGTGATA GAGGAATCCA TCTTGCAGTC AGATAAAGCC 
CTCACTGATA GAGAGAAGGC AGTAGCAGTG GATCGGGCCA AGAAGGAGGC AGCTGAGAAG 
GAACAGGAAC TTTTAAAACA GAAATTACAG GAGCAGCAGC AACAGATGGA GGCTCAAGAT 
AAGAGTCGCA AGGAAAACAT AGCCCAACTG AAGGAGAAGC TGCAGATGGA GAGAGAACAC 
CTACTGAGAG AGCAGATTAT GATGTTGGAG CACACGCAGA AGGTCCAAAA TGATTGGCTT 
CATGAAGGAT TTAAGAAGAA GTATGAGGAG ATGAATGCAG AGATAAGTCA ATTTAAACGT 
ATGATTGATA CTACAAAAAA TGATGATACT CCCTGGATTG CACGAACCTT GGACAACCTT 
GCCGATGAGC TAACTGCAAT ATTGTCTGCT CCTGCTAAAT TAATTGGTCA TGGTGTCAAA 
GGTGTGAGCT CACTCTTTAA AAAGCATAAG CTCCCCTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GBP6 ( NM_001320257.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001307186.1 Homo sapiens guanylate binding protein family member 6 (GBP6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu33076
Clone ID Related Accession (Same CDS sequence)	NM_001320257.1
Accession Version	NM_001320257.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1512bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-30
Organism	Homo sapiens(human)
Product	guanylate-binding protein 6 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA437660.1, DA447005.1, AK299466.1, AK303987.1, BX647907.1 and AL691464.4. On Feb 18, 2016 this sequence version replaced XM_005270549.3. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and uses an downstream in-frame start codon, compared to variant 1. It encodes isoform 2, which is shorter at the N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK299466.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145245, SAMEA2147975 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCACCA TCAACCACCA GGCCCTGGAG CAGCTGCATT ATGTGACGGA GCTCACAGAA 
CTAATTAAGG CAAAGTCCTC CCCAAGGCCT GATGGAGTAG AAGATTCCAC AGAGTTTGTG 
AGTTTCTTCC CAGACTTTCT TTGGACAGTA CGGGATTTCA CTCTGGAGCT GAAGTTGAAC 
GGTCACCCTA TCACAGAAGA TGAATACCTG GAGAATGCCT TGAAGCTGAT TCAAGGCAAT 
AATCCCAGAG TTCAAACATC CAATTTTCCC AGGGAGTGCA TCAGGCGTTT CTTTCCAAAA 
CGGAAGTGTT TCGTCTTTGA CCGGCCAACA AATGACAAAG ACCTTCTAGC CAATATTGAG 
AAGGTGTCAG AAAAGCAACT GGATCCCAAA TTCCAGGAAC AAACAAACAT TTTCTGTTCT 
TACATCTTCA CTCATGCAAG AACCAAGACC CTCAGGGAGG GAATCACAGT CACTGGGAAT 
CGTCTGGGAA CTCTGGCAGT GACTTATGTA GAGGCCATCA ACAGTGGAGC AGTGCCTTGT 
CTGGAGAATG CAGTGATAAC TCTGGCCCAG CGTGAGAACT CAGCGGCCGT GCAGAGGGCA 
GCTGACTACT ACAGCCAGCA GATGGCCCAG CGAGTGAAGC TCCCCACAGA CACGCTCCAG 
GAGCTGCTGG ACATGCATGC GGCCTGTGAG AGGGAAGCCA TTGCAATCTT CATGGAGCAC 
TCCTTCAAGG ATGAAAATCA GGAATTCCAG AAGAAGTTCA TGGAAACCAC AATGAATAAG 
AAGGGGGATT TCTTGCTGCA GAATGAAGAG TCATCTGTTC AATACTGCCA GGCTAAACTC 
AATGAGCTCT CAAAGGGACT AATGGAAAGT ATCTCAGCAG GAAGTTTCTC TGTTCCTGGA 
GGGCACAAGC TCTACATGGA AACAAAGGAA AGGATTGAAC AGGACTATTG GCAAGTTCCC 
AGGAAAGGAG TAAAGGCAAA AGAGGTCTTC CAGAGGTTCC TGGAGTCACA GATGGTGATA 
GAGGAATCCA TCTTGCAGTC AGATAAAGCC CTCACTGATA GAGAGAAGGC AGTAGCAGTG 
GATCGGGCCA AGAAGGAGGC AGCTGAGAAG GAACAGGAAC TTTTAAAACA GAAATTACAG 
GAGCAGCAGC AACAGATGGA GGCTCAAGAT AAGAGTCGCA AGGAAAACAT AGCCCAACTG 
AAGGAGAAGC TGCAGATGGA GAGAGAACAC CTACTGAGAG AGCAGATTAT GATGTTGGAG 
CACACGCAGA AGGTCCAAAA TGATTGGCTT CATGAAGGAT TTAAGAAGAA GTATGAGGAG 
ATGAATGCAG AGATAAGTCA ATTTAAACGT ATGATTGATA CTACAAAAAA TGATGATACT 
CCCTGGATTG CACGAACCTT GGACAACCTT GCCGATGAGC TAACTGCAAT ATTGTCTGCT 
CCTGCTAAAT TAATTGGTCA TGGTGTCAAA GGTGTGAGCT CACTCTTTAA AAAGCATAAG 
CTCCCCTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001307186.1
CDS	324..1835
Translation	MSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTVRDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPTNDKDLLANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVTYVEAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIARTLDNLADELTAILSAPAKLIGHGVKGVSSLFKKHKLPF

Target ORF information:

RefSeq Version	NM_001320257.1
Organism	Homo sapiens(human)
Definition	Homo sapiens guanylate binding protein family member 6 (GBP6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001320257.1

ORF Insert Sequence:

ATGAGCACCA TCAACCACCA GGCCCTGGAG CAGCTGCATT ATGTGACGGA GCTCACAGAA 
CTAATTAAGG CAAAGTCCTC CCCAAGGCCT GATGGAGTAG AAGATTCCAC AGAGTTTGTG 
AGTTTCTTCC CAGACTTTCT TTGGACAGTA CGGGATTTCA CTCTGGAGCT GAAGTTGAAC 
GGTCACCCTA TCACAGAAGA TGAATACCTG GAGAATGCCT TGAAGCTGAT TCAAGGCAAT 
AATCCCAGAG TTCAAACATC CAATTTTCCC AGGGAGTGCA TCAGGCGTTT CTTTCCAAAA 
CGGAAGTGTT TCGTCTTTGA CCGGCCAACA AATGACAAAG ACCTTCTAGC CAATATTGAG 
AAGGTGTCAG AAAAGCAACT GGATCCCAAA TTCCAGGAAC AAACAAACAT TTTCTGTTCT 
TACATCTTCA CTCATGCAAG AACCAAGACC CTCAGGGAGG GAATCACAGT CACTGGGAAT 
CGTCTGGGAA CTCTGGCAGT GACTTATGTA GAGGCCATCA ACAGTGGAGC AGTGCCTTGT 
CTGGAGAATG CAGTGATAAC TCTGGCCCAG CGTGAGAACT CAGCGGCCGT GCAGAGGGCA 
GCTGACTACT ACAGCCAGCA GATGGCCCAG CGAGTGAAGC TCCCCACAGA CACGCTCCAG 
GAGCTGCTGG ACATGCATGC GGCCTGTGAG AGGGAAGCCA TTGCAATCTT CATGGAGCAC 
TCCTTCAAGG ATGAAAATCA GGAATTCCAG AAGAAGTTCA TGGAAACCAC AATGAATAAG 
AAGGGGGATT TCTTGCTGCA GAATGAAGAG TCATCTGTTC AATACTGCCA GGCTAAACTC 
AATGAGCTCT CAAAGGGACT AATGGAAAGT ATCTCAGCAG GAAGTTTCTC TGTTCCTGGA 
GGGCACAAGC TCTACATGGA AACAAAGGAA AGGATTGAAC AGGACTATTG GCAAGTTCCC 
AGGAAAGGAG TAAAGGCAAA AGAGGTCTTC CAGAGGTTCC TGGAGTCACA GATGGTGATA 
GAGGAATCCA TCTTGCAGTC AGATAAAGCC CTCACTGATA GAGAGAAGGC AGTAGCAGTG 
GATCGGGCCA AGAAGGAGGC AGCTGAGAAG GAACAGGAAC TTTTAAAACA GAAATTACAG 
GAGCAGCAGC AACAGATGGA GGCTCAAGAT AAGAGTCGCA AGGAAAACAT AGCCCAACTG 
AAGGAGAAGC TGCAGATGGA GAGAGAACAC CTACTGAGAG AGCAGATTAT GATGTTGGAG 
CACACGCAGA AGGTCCAAAA TGATTGGCTT CATGAAGGAT TTAAGAAGAA GTATGAGGAG 
ATGAATGCAG AGATAAGTCA ATTTAAACGT ATGATTGATA CTACAAAAAA TGATGATACT 
CCCTGGATTG CACGAACCTT GGACAACCTT GCCGATGAGC TAACTGCAAT ATTGTCTGCT 
CCTGCTAAAT TAATTGGTCA TGGTGTCAAA GGTGTGAGCT CACTCTTTAA AAAGCATAAG 
CTCCCCTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GBP6 ( XM_011540835.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011539137.1 Homo sapiens guanylate binding protein family member 6 (GBP6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu08935
Clone ID Related Accession (Same CDS sequence)	NM_198460.2 , NM_198460.3 , XM_011540835.3 , XM_011540835.2
Accession Version	XM_011540835.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1902bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	guanylate-binding protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011540835.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAATCTG GACCCAAAAT GTTGGCCCCC GTTTGCCTGG TGGAAAATAA CAATGAGCAG 
CTATTGGTGA ACCAGCAAGC TATACAGATT CTTGAAAAGA TTTCTCAGCC AGTGGTGGTG 
GTGGCCATTG TAGGACTGTA CCGTACAGGG AAATCCTACT TGATGAACCA TCTGGCAGGA 
CAGAATCATG GCTTCCCTCT GGGCTCCACG GTGCAGTCTG AAACCAAGGG CATCTGGATG 
TGGTGCGTGC CCCACCCATC CAAGCCAAAC CACACCCTGG TCCTTCTGGA CACCGAAGGT 
CTGGGCGATG TGGAAAAGGG TGACCCTAAG AATGACTCCT GGATCTTTGC CCTGGCTGTG 
CTCCTGTGCA GCACCTTTGT CTACAACAGC ATGAGCACCA TCAACCACCA GGCCCTGGAG 
CAGCTGCATT ATGTGACGGA GCTCACAGAA CTAATTAAGG CAAAGTCCTC CCCAAGGCCT 
GATGGAGTAG AAGATTCCAC AGAGTTTGTG AGTTTCTTCC CAGACTTTCT TTGGACAGTA 
CGGGATTTCA CTCTGGAGCT GAAGTTGAAC GGTCACCCTA TCACAGAAGA TGAATACCTG 
GAGAATGCCT TGAAGCTGAT TCAAGGCAAT AATCCCAGAG TTCAAACATC CAATTTTCCC 
AGGGAGTGCA TCAGGCGTTT CTTTCCAAAA CGGAAGTGTT TCGTCTTTGA CCGGCCAACA 
AATGACAAAG ACCTTCTAGC CAATATTGAG AAGGTGTCAG AAAAGCAACT GGATCCCAAA 
TTCCAGGAAC AAACAAACAT TTTCTGTTCT TACATCTTCA CTCATGCAAG AACCAAGACC 
CTCAGGGAGG GAATCACAGT CACTGGGAAT CGTCTGGGAA CTCTGGCAGT GACTTATGTA 
GAGGCCATCA ACAGTGGAGC AGTGCCTTGT CTGGAGAATG CAGTGATAAC TCTGGCCCAG 
CGTGAGAACT CAGCGGCCGT GCAGAGGGCA GCTGACTACT ACAGCCAGCA GATGGCCCAG 
CGAGTGAAGC TCCCCACAGA CACGCTCCAG GAGCTGCTGG ACATGCATGC GGCCTGTGAG 
AGGGAAGCCA TTGCAATCTT CATGGAGCAC TCCTTCAAGG ATGAAAATCA GGAATTCCAG 
AAGAAGTTCA TGGAAACCAC AATGAATAAG AAGGGGGATT TCTTGCTGCA GAATGAAGAG 
TCATCTGTTC AATACTGCCA GGCTAAACTC AATGAGCTCT CAAAGGGACT AATGGAAAGT 
ATCTCAGCAG GAAGTTTCTC TGTTCCTGGA GGGCACAAGC TCTACATGGA AACAAAGGAA 
AGGATTGAAC AGGACTATTG GCAAGTTCCC AGGAAAGGAG TAAAGGCAAA AGAGGTCTTC 
CAGAGGTTCC TGGAGTCACA GATGGTGATA GAGGAATCCA TCTTGCAGTC AGATAAAGCC 
CTCACTGATA GAGAGAAGGC AGTAGCAGTG GATCGGGCCA AGAAGGAGGC AGCTGAGAAG 
GAACAGGAAC TTTTAAAACA GAAATTACAG GAGCAGCAGC AACAGATGGA GGCTCAAGAT 
AAGAGTCGCA AGGAAAACAT AGCCCAACTG AAGGAGAAGC TGCAGATGGA GAGAGAACAC 
CTACTGAGAG AGCAGATTAT GATGTTGGAG CACACGCAGA AGGTCCAAAA TGATTGGCTT 
CATGAAGGAT TTAAGAAGAA GTATGAGGAG ATGAATGCAG AGATAAGTCA ATTTAAACGT 
ATGATTGATA CTACAAAAAA TGATGATACT CCCTGGATTG CACGAACCTT GGACAACCTT 
GCCGATGAGC TAACTGCAAT ATTGTCTGCT CCTGCTAAAT TAATTGGTCA TGGTGTCAAA 
GGTGTGAGCT CACTCTTTAA AAAGCATAAG CTCCCCTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011539137.1
CDS	83..1984
Translation	MESGPKMLAPVCLVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAGQNHGFPLGSTVQSETKGIWMWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTVRDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPTNDKDLLANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVTYVEAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIARTLDNLADELTAILSAPAKLIGHGVKGVSSLFKKHKLPF

Target ORF information:

RefSeq Version	XM_011540835.3
Organism	Homo sapiens(human)
Definition	Homo sapiens guanylate binding protein family member 6 (GBP6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011540835.3

ORF Insert Sequence:

ATGGAATCTG GACCCAAAAT GTTGGCCCCC GTTTGCCTGG TGGAAAATAA CAATGAGCAG 
CTATTGGTGA ACCAGCAAGC TATACAGATT CTTGAAAAGA TTTCTCAGCC AGTGGTGGTG 
GTGGCCATTG TAGGACTGTA CCGTACAGGG AAATCCTACT TGATGAACCA TCTGGCAGGA 
CAGAATCATG GCTTCCCTCT GGGCTCCACG GTGCAGTCTG AAACCAAGGG CATCTGGATG 
TGGTGCGTGC CCCACCCATC CAAGCCAAAC CACACCCTGG TCCTTCTGGA CACCGAAGGT 
CTGGGCGATG TGGAAAAGGG TGACCCTAAG AATGACTCCT GGATCTTTGC CCTGGCTGTG 
CTCCTGTGCA GCACCTTTGT CTACAACAGC ATGAGCACCA TCAACCACCA GGCCCTGGAG 
CAGCTGCATT ATGTGACGGA GCTCACAGAA CTAATTAAGG CAAAGTCCTC CCCAAGGCCT 
GATGGAGTAG AAGATTCCAC AGAGTTTGTG AGTTTCTTCC CAGACTTTCT TTGGACAGTA 
CGGGATTTCA CTCTGGAGCT GAAGTTGAAC GGTCACCCTA TCACAGAAGA TGAATACCTG 
GAGAATGCCT TGAAGCTGAT TCAAGGCAAT AATCCCAGAG TTCAAACATC CAATTTTCCC 
AGGGAGTGCA TCAGGCGTTT CTTTCCAAAA CGGAAGTGTT TCGTCTTTGA CCGGCCAACA 
AATGACAAAG ACCTTCTAGC CAATATTGAG AAGGTGTCAG AAAAGCAACT GGATCCCAAA 
TTCCAGGAAC AAACAAACAT TTTCTGTTCT TACATCTTCA CTCATGCAAG AACCAAGACC 
CTCAGGGAGG GAATCACAGT CACTGGGAAT CGTCTGGGAA CTCTGGCAGT GACTTATGTA 
GAGGCCATCA ACAGTGGAGC AGTGCCTTGT CTGGAGAATG CAGTGATAAC TCTGGCCCAG 
CGTGAGAACT CAGCGGCCGT GCAGAGGGCA GCTGACTACT ACAGCCAGCA GATGGCCCAG 
CGAGTGAAGC TCCCCACAGA CACGCTCCAG GAGCTGCTGG ACATGCATGC GGCCTGTGAG 
AGGGAAGCCA TTGCAATCTT CATGGAGCAC TCCTTCAAGG ATGAAAATCA GGAATTCCAG 
AAGAAGTTCA TGGAAACCAC AATGAATAAG AAGGGGGATT TCTTGCTGCA GAATGAAGAG 
TCATCTGTTC AATACTGCCA GGCTAAACTC AATGAGCTCT CAAAGGGACT AATGGAAAGT 
ATCTCAGCAG GAAGTTTCTC TGTTCCTGGA GGGCACAAGC TCTACATGGA AACAAAGGAA 
AGGATTGAAC AGGACTATTG GCAAGTTCCC AGGAAAGGAG TAAAGGCAAA AGAGGTCTTC 
CAGAGGTTCC TGGAGTCACA GATGGTGATA GAGGAATCCA TCTTGCAGTC AGATAAAGCC 
CTCACTGATA GAGAGAAGGC AGTAGCAGTG GATCGGGCCA AGAAGGAGGC AGCTGAGAAG 
GAACAGGAAC TTTTAAAACA GAAATTACAG GAGCAGCAGC AACAGATGGA GGCTCAAGAT 
AAGAGTCGCA AGGAAAACAT AGCCCAACTG AAGGAGAAGC TGCAGATGGA GAGAGAACAC 
CTACTGAGAG AGCAGATTAT GATGTTGGAG CACACGCAGA AGGTCCAAAA TGATTGGCTT 
CATGAAGGAT TTAAGAAGAA GTATGAGGAG ATGAATGCAG AGATAAGTCA ATTTAAACGT 
ATGATTGATA CTACAAAAAA TGATGATACT CCCTGGATTG CACGAACCTT GGACAACCTT 
GCCGATGAGC TAACTGCAAT ATTGTCTGCT CCTGCTAAAT TAATTGGTCA TGGTGTCAAA 
GGTGTGAGCT CACTCTTTAA AAAGCATAAG CTCCCCTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GBP6 ( XM_011540835.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011539137.1 Homo sapiens guanylate binding protein family member 6 (GBP6), transcript variant X1, mRNA.

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CloneID	OHu08935
Clone ID Related Accession (Same CDS sequence)	NM_198460.2 , NM_198460.3 , XM_011540835.3 , XM_011540835.2
Accession Version	XM_011540835.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1902bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	guanylate-binding protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011540835.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAATCTG GACCCAAAAT GTTGGCCCCC GTTTGCCTGG TGGAAAATAA CAATGAGCAG 
CTATTGGTGA ACCAGCAAGC TATACAGATT CTTGAAAAGA TTTCTCAGCC AGTGGTGGTG 
GTGGCCATTG TAGGACTGTA CCGTACAGGG AAATCCTACT TGATGAACCA TCTGGCAGGA 
CAGAATCATG GCTTCCCTCT GGGCTCCACG GTGCAGTCTG AAACCAAGGG CATCTGGATG 
TGGTGCGTGC CCCACCCATC CAAGCCAAAC CACACCCTGG TCCTTCTGGA CACCGAAGGT 
CTGGGCGATG TGGAAAAGGG TGACCCTAAG AATGACTCCT GGATCTTTGC CCTGGCTGTG 
CTCCTGTGCA GCACCTTTGT CTACAACAGC ATGAGCACCA TCAACCACCA GGCCCTGGAG 
CAGCTGCATT ATGTGACGGA GCTCACAGAA CTAATTAAGG CAAAGTCCTC CCCAAGGCCT 
GATGGAGTAG AAGATTCCAC AGAGTTTGTG AGTTTCTTCC CAGACTTTCT TTGGACAGTA 
CGGGATTTCA CTCTGGAGCT GAAGTTGAAC GGTCACCCTA TCACAGAAGA TGAATACCTG 
GAGAATGCCT TGAAGCTGAT TCAAGGCAAT AATCCCAGAG TTCAAACATC CAATTTTCCC 
AGGGAGTGCA TCAGGCGTTT CTTTCCAAAA CGGAAGTGTT TCGTCTTTGA CCGGCCAACA 
AATGACAAAG ACCTTCTAGC CAATATTGAG AAGGTGTCAG AAAAGCAACT GGATCCCAAA 
TTCCAGGAAC AAACAAACAT TTTCTGTTCT TACATCTTCA CTCATGCAAG AACCAAGACC 
CTCAGGGAGG GAATCACAGT CACTGGGAAT CGTCTGGGAA CTCTGGCAGT GACTTATGTA 
GAGGCCATCA ACAGTGGAGC AGTGCCTTGT CTGGAGAATG CAGTGATAAC TCTGGCCCAG 
CGTGAGAACT CAGCGGCCGT GCAGAGGGCA GCTGACTACT ACAGCCAGCA GATGGCCCAG 
CGAGTGAAGC TCCCCACAGA CACGCTCCAG GAGCTGCTGG ACATGCATGC GGCCTGTGAG 
AGGGAAGCCA TTGCAATCTT CATGGAGCAC TCCTTCAAGG ATGAAAATCA GGAATTCCAG 
AAGAAGTTCA TGGAAACCAC AATGAATAAG AAGGGGGATT TCTTGCTGCA GAATGAAGAG 
TCATCTGTTC AATACTGCCA GGCTAAACTC AATGAGCTCT CAAAGGGACT AATGGAAAGT 
ATCTCAGCAG GAAGTTTCTC TGTTCCTGGA GGGCACAAGC TCTACATGGA AACAAAGGAA 
AGGATTGAAC AGGACTATTG GCAAGTTCCC AGGAAAGGAG TAAAGGCAAA AGAGGTCTTC 
CAGAGGTTCC TGGAGTCACA GATGGTGATA GAGGAATCCA TCTTGCAGTC AGATAAAGCC 
CTCACTGATA GAGAGAAGGC AGTAGCAGTG GATCGGGCCA AGAAGGAGGC AGCTGAGAAG 
GAACAGGAAC TTTTAAAACA GAAATTACAG GAGCAGCAGC AACAGATGGA GGCTCAAGAT 
AAGAGTCGCA AGGAAAACAT AGCCCAACTG AAGGAGAAGC TGCAGATGGA GAGAGAACAC 
CTACTGAGAG AGCAGATTAT GATGTTGGAG CACACGCAGA AGGTCCAAAA TGATTGGCTT 
CATGAAGGAT TTAAGAAGAA GTATGAGGAG ATGAATGCAG AGATAAGTCA ATTTAAACGT 
ATGATTGATA CTACAAAAAA TGATGATACT CCCTGGATTG CACGAACCTT GGACAACCTT 
GCCGATGAGC TAACTGCAAT ATTGTCTGCT CCTGCTAAAT TAATTGGTCA TGGTGTCAAA 
GGTGTGAGCT CACTCTTTAA AAAGCATAAG CTCCCCTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011539137.1
CDS	104..2005
Translation	MESGPKMLAPVCLVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAGQNHGFPLGSTVQSETKGIWMWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTVRDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPTNDKDLLANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVTYVEAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIARTLDNLADELTAILSAPAKLIGHGVKGVSSLFKKHKLPF

Target ORF information:

RefSeq Version	XM_011540835.2
Organism	Homo sapiens(human)
Definition	Homo sapiens guanylate binding protein family member 6 (GBP6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011540835.2

ORF Insert Sequence:

ATGGAATCTG GACCCAAAAT GTTGGCCCCC GTTTGCCTGG TGGAAAATAA CAATGAGCAG 
CTATTGGTGA ACCAGCAAGC TATACAGATT CTTGAAAAGA TTTCTCAGCC AGTGGTGGTG 
GTGGCCATTG TAGGACTGTA CCGTACAGGG AAATCCTACT TGATGAACCA TCTGGCAGGA 
CAGAATCATG GCTTCCCTCT GGGCTCCACG GTGCAGTCTG AAACCAAGGG CATCTGGATG 
TGGTGCGTGC CCCACCCATC CAAGCCAAAC CACACCCTGG TCCTTCTGGA CACCGAAGGT 
CTGGGCGATG TGGAAAAGGG TGACCCTAAG AATGACTCCT GGATCTTTGC CCTGGCTGTG 
CTCCTGTGCA GCACCTTTGT CTACAACAGC ATGAGCACCA TCAACCACCA GGCCCTGGAG 
CAGCTGCATT ATGTGACGGA GCTCACAGAA CTAATTAAGG CAAAGTCCTC CCCAAGGCCT 
GATGGAGTAG AAGATTCCAC AGAGTTTGTG AGTTTCTTCC CAGACTTTCT TTGGACAGTA 
CGGGATTTCA CTCTGGAGCT GAAGTTGAAC GGTCACCCTA TCACAGAAGA TGAATACCTG 
GAGAATGCCT TGAAGCTGAT TCAAGGCAAT AATCCCAGAG TTCAAACATC CAATTTTCCC 
AGGGAGTGCA TCAGGCGTTT CTTTCCAAAA CGGAAGTGTT TCGTCTTTGA CCGGCCAACA 
AATGACAAAG ACCTTCTAGC CAATATTGAG AAGGTGTCAG AAAAGCAACT GGATCCCAAA 
TTCCAGGAAC AAACAAACAT TTTCTGTTCT TACATCTTCA CTCATGCAAG AACCAAGACC 
CTCAGGGAGG GAATCACAGT CACTGGGAAT CGTCTGGGAA CTCTGGCAGT GACTTATGTA 
GAGGCCATCA ACAGTGGAGC AGTGCCTTGT CTGGAGAATG CAGTGATAAC TCTGGCCCAG 
CGTGAGAACT CAGCGGCCGT GCAGAGGGCA GCTGACTACT ACAGCCAGCA GATGGCCCAG 
CGAGTGAAGC TCCCCACAGA CACGCTCCAG GAGCTGCTGG ACATGCATGC GGCCTGTGAG 
AGGGAAGCCA TTGCAATCTT CATGGAGCAC TCCTTCAAGG ATGAAAATCA GGAATTCCAG 
AAGAAGTTCA TGGAAACCAC AATGAATAAG AAGGGGGATT TCTTGCTGCA GAATGAAGAG 
TCATCTGTTC AATACTGCCA GGCTAAACTC AATGAGCTCT CAAAGGGACT AATGGAAAGT 
ATCTCAGCAG GAAGTTTCTC TGTTCCTGGA GGGCACAAGC TCTACATGGA AACAAAGGAA 
AGGATTGAAC AGGACTATTG GCAAGTTCCC AGGAAAGGAG TAAAGGCAAA AGAGGTCTTC 
CAGAGGTTCC TGGAGTCACA GATGGTGATA GAGGAATCCA TCTTGCAGTC AGATAAAGCC 
CTCACTGATA GAGAGAAGGC AGTAGCAGTG GATCGGGCCA AGAAGGAGGC AGCTGAGAAG 
GAACAGGAAC TTTTAAAACA GAAATTACAG GAGCAGCAGC AACAGATGGA GGCTCAAGAT 
AAGAGTCGCA AGGAAAACAT AGCCCAACTG AAGGAGAAGC TGCAGATGGA GAGAGAACAC 
CTACTGAGAG AGCAGATTAT GATGTTGGAG CACACGCAGA AGGTCCAAAA TGATTGGCTT 
CATGAAGGAT TTAAGAAGAA GTATGAGGAG ATGAATGCAG AGATAAGTCA ATTTAAACGT 
ATGATTGATA CTACAAAAAA TGATGATACT CCCTGGATTG CACGAACCTT GGACAACCTT 
GCCGATGAGC TAACTGCAAT ATTGTCTGCT CCTGCTAAAT TAATTGGTCA TGGTGTCAAA 
GGTGTGAGCT CACTCTTTAA AAAGCATAAG CTCCCCTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GBP6 ( NM_198460.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_940862.2 Homo sapiens guanylate binding protein family member 6 (GBP6), transcript variant 1, mRNA.

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CloneID	OHu08935
Clone ID Related Accession (Same CDS sequence)	NM_198460.2 , NM_198460.3 , XM_011540835.3 , XM_011540835.2
Accession Version	NM_198460.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1902bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-29
Organism	Homo sapiens(human)
Product	guanylate-binding protein 6 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK131356.1, AL691464.4 and AI199897.1. On Nov 30, 2019 this sequence version replaced NM_198460.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK315834.1, BX537949.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAATCTG GACCCAAAAT GTTGGCCCCC GTTTGCCTGG TGGAAAATAA CAATGAGCAG 
CTATTGGTGA ACCAGCAAGC TATACAGATT CTTGAAAAGA TTTCTCAGCC AGTGGTGGTG 
GTGGCCATTG TAGGACTGTA CCGTACAGGG AAATCCTACT TGATGAACCA TCTGGCAGGA 
CAGAATCATG GCTTCCCTCT GGGCTCCACG GTGCAGTCTG AAACCAAGGG CATCTGGATG 
TGGTGCGTGC CCCACCCATC CAAGCCAAAC CACACCCTGG TCCTTCTGGA CACCGAAGGT 
CTGGGCGATG TGGAAAAGGG TGACCCTAAG AATGACTCCT GGATCTTTGC CCTGGCTGTG 
CTCCTGTGCA GCACCTTTGT CTACAACAGC ATGAGCACCA TCAACCACCA GGCCCTGGAG 
CAGCTGCATT ATGTGACGGA GCTCACAGAA CTAATTAAGG CAAAGTCCTC CCCAAGGCCT 
GATGGAGTAG AAGATTCCAC AGAGTTTGTG AGTTTCTTCC CAGACTTTCT TTGGACAGTA 
CGGGATTTCA CTCTGGAGCT GAAGTTGAAC GGTCACCCTA TCACAGAAGA TGAATACCTG 
GAGAATGCCT TGAAGCTGAT TCAAGGCAAT AATCCCAGAG TTCAAACATC CAATTTTCCC 
AGGGAGTGCA TCAGGCGTTT CTTTCCAAAA CGGAAGTGTT TCGTCTTTGA CCGGCCAACA 
AATGACAAAG ACCTTCTAGC CAATATTGAG AAGGTGTCAG AAAAGCAACT GGATCCCAAA 
TTCCAGGAAC AAACAAACAT TTTCTGTTCT TACATCTTCA CTCATGCAAG AACCAAGACC 
CTCAGGGAGG GAATCACAGT CACTGGGAAT CGTCTGGGAA CTCTGGCAGT GACTTATGTA 
GAGGCCATCA ACAGTGGAGC AGTGCCTTGT CTGGAGAATG CAGTGATAAC TCTGGCCCAG 
CGTGAGAACT CAGCGGCCGT GCAGAGGGCA GCTGACTACT ACAGCCAGCA GATGGCCCAG 
CGAGTGAAGC TCCCCACAGA CACGCTCCAG GAGCTGCTGG ACATGCATGC GGCCTGTGAG 
AGGGAAGCCA TTGCAATCTT CATGGAGCAC TCCTTCAAGG ATGAAAATCA GGAATTCCAG 
AAGAAGTTCA TGGAAACCAC AATGAATAAG AAGGGGGATT TCTTGCTGCA GAATGAAGAG 
TCATCTGTTC AATACTGCCA GGCTAAACTC AATGAGCTCT CAAAGGGACT AATGGAAAGT 
ATCTCAGCAG GAAGTTTCTC TGTTCCTGGA GGGCACAAGC TCTACATGGA AACAAAGGAA 
AGGATTGAAC AGGACTATTG GCAAGTTCCC AGGAAAGGAG TAAAGGCAAA AGAGGTCTTC 
CAGAGGTTCC TGGAGTCACA GATGGTGATA GAGGAATCCA TCTTGCAGTC AGATAAAGCC 
CTCACTGATA GAGAGAAGGC AGTAGCAGTG GATCGGGCCA AGAAGGAGGC AGCTGAGAAG 
GAACAGGAAC TTTTAAAACA GAAATTACAG GAGCAGCAGC AACAGATGGA GGCTCAAGAT 
AAGAGTCGCA AGGAAAACAT AGCCCAACTG AAGGAGAAGC TGCAGATGGA GAGAGAACAC 
CTACTGAGAG AGCAGATTAT GATGTTGGAG CACACGCAGA AGGTCCAAAA TGATTGGCTT 
CATGAAGGAT TTAAGAAGAA GTATGAGGAG ATGAATGCAG AGATAAGTCA ATTTAAACGT 
ATGATTGATA CTACAAAAAA TGATGATACT CCCTGGATTG CACGAACCTT GGACAACCTT 
GCCGATGAGC TAACTGCAAT ATTGTCTGCT CCTGCTAAAT TAATTGGTCA TGGTGTCAAA 
GGTGTGAGCT CACTCTTTAA AAAGCATAAG CTCCCCTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_940862.2
CDS	93..1994
Translation	MESGPKMLAPVCLVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAGQNHGFPLGSTVQSETKGIWMWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTVRDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPTNDKDLLANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVTYVEAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIARTLDNLADELTAILSAPAKLIGHGVKGVSSLFKKHKLPF

Target ORF information:

RefSeq Version	NM_198460.3
Organism	Homo sapiens(human)
Definition	Homo sapiens guanylate binding protein family member 6 (GBP6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198460.3

ORF Insert Sequence:

ATGGAATCTG GACCCAAAAT GTTGGCCCCC GTTTGCCTGG TGGAAAATAA CAATGAGCAG 
CTATTGGTGA ACCAGCAAGC TATACAGATT CTTGAAAAGA TTTCTCAGCC AGTGGTGGTG 
GTGGCCATTG TAGGACTGTA CCGTACAGGG AAATCCTACT TGATGAACCA TCTGGCAGGA 
CAGAATCATG GCTTCCCTCT GGGCTCCACG GTGCAGTCTG AAACCAAGGG CATCTGGATG 
TGGTGCGTGC CCCACCCATC CAAGCCAAAC CACACCCTGG TCCTTCTGGA CACCGAAGGT 
CTGGGCGATG TGGAAAAGGG TGACCCTAAG AATGACTCCT GGATCTTTGC CCTGGCTGTG 
CTCCTGTGCA GCACCTTTGT CTACAACAGC ATGAGCACCA TCAACCACCA GGCCCTGGAG 
CAGCTGCATT ATGTGACGGA GCTCACAGAA CTAATTAAGG CAAAGTCCTC CCCAAGGCCT 
GATGGAGTAG AAGATTCCAC AGAGTTTGTG AGTTTCTTCC CAGACTTTCT TTGGACAGTA 
CGGGATTTCA CTCTGGAGCT GAAGTTGAAC GGTCACCCTA TCACAGAAGA TGAATACCTG 
GAGAATGCCT TGAAGCTGAT TCAAGGCAAT AATCCCAGAG TTCAAACATC CAATTTTCCC 
AGGGAGTGCA TCAGGCGTTT CTTTCCAAAA CGGAAGTGTT TCGTCTTTGA CCGGCCAACA 
AATGACAAAG ACCTTCTAGC CAATATTGAG AAGGTGTCAG AAAAGCAACT GGATCCCAAA 
TTCCAGGAAC AAACAAACAT TTTCTGTTCT TACATCTTCA CTCATGCAAG AACCAAGACC 
CTCAGGGAGG GAATCACAGT CACTGGGAAT CGTCTGGGAA CTCTGGCAGT GACTTATGTA 
GAGGCCATCA ACAGTGGAGC AGTGCCTTGT CTGGAGAATG CAGTGATAAC TCTGGCCCAG 
CGTGAGAACT CAGCGGCCGT GCAGAGGGCA GCTGACTACT ACAGCCAGCA GATGGCCCAG 
CGAGTGAAGC TCCCCACAGA CACGCTCCAG GAGCTGCTGG ACATGCATGC GGCCTGTGAG 
AGGGAAGCCA TTGCAATCTT CATGGAGCAC TCCTTCAAGG ATGAAAATCA GGAATTCCAG 
AAGAAGTTCA TGGAAACCAC AATGAATAAG AAGGGGGATT TCTTGCTGCA GAATGAAGAG 
TCATCTGTTC AATACTGCCA GGCTAAACTC AATGAGCTCT CAAAGGGACT AATGGAAAGT 
ATCTCAGCAG GAAGTTTCTC TGTTCCTGGA GGGCACAAGC TCTACATGGA AACAAAGGAA 
AGGATTGAAC AGGACTATTG GCAAGTTCCC AGGAAAGGAG TAAAGGCAAA AGAGGTCTTC 
CAGAGGTTCC TGGAGTCACA GATGGTGATA GAGGAATCCA TCTTGCAGTC AGATAAAGCC 
CTCACTGATA GAGAGAAGGC AGTAGCAGTG GATCGGGCCA AGAAGGAGGC AGCTGAGAAG 
GAACAGGAAC TTTTAAAACA GAAATTACAG GAGCAGCAGC AACAGATGGA GGCTCAAGAT 
AAGAGTCGCA AGGAAAACAT AGCCCAACTG AAGGAGAAGC TGCAGATGGA GAGAGAACAC 
CTACTGAGAG AGCAGATTAT GATGTTGGAG CACACGCAGA AGGTCCAAAA TGATTGGCTT 
CATGAAGGAT TTAAGAAGAA GTATGAGGAG ATGAATGCAG AGATAAGTCA ATTTAAACGT 
ATGATTGATA CTACAAAAAA TGATGATACT CCCTGGATTG CACGAACCTT GGACAACCTT 
GCCGATGAGC TAACTGCAAT ATTGTCTGCT CCTGCTAAAT TAATTGGTCA TGGTGTCAAA 
GGTGTGAGCT CACTCTTTAA AAAGCATAAG CTCCCCTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

New genetic associations detected in a host response study to hepatitis B vaccine.
Genes and immunity11(3)232-8(2010 Apr)
Davila S,Froeling FE,Tan A,Bonnard C,Boland GJ,Snippe H,Hibberd ML,Seielstad M

Lack of replication of genetic predictors for the rheumatoid arthritis response to anti-TNF treatments: a prospective case-only study.
Arthritis research & therapy12(2)R72(2010)
Suarez-Gestal M,Perez-Pampin E,Calaza M,Gomez-Reino JJ,Gonzalez A

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Journal of proteome research8(3)1304-14(2009 Mar)
Gonzalez-Begne M,Lu B,Han X,Hagen FK,Hand AR,Melvin JE,Yates JR

In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research26(5)328-52(2006 May)
Olszewski MA,Gray J,Vestal DJ

Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.
EMBO reports1(3)287-92(2000 Sep)
Simpson JC,Wellenreuther R,Poustka A,Pepperkok R,Wiemann S

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GBP6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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