TRPV3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TRPV3
Entrez Gene ID	162514
Full Name	transient receptor potential cation channel subfamily V member 3
Synonyms	FNEPPK2,OLMS,VRL3
General protein information	Preferred Names transient receptor potential cation channel subfamily V member 3 Names transient receptor potential cation channel subfamily V member 3 VRL-3 vanilloid receptor-like 3 vanilloid receptor-related osmotically activated channel protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17p13.2
Summary	This gene product belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. This gene lies in close proximity to another family member gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].
Disorder MIM:	607066
Disorder Html:	Olmsted syndrome, 614594 (3); ?Palmoplantar keratoderma, nonepidermolytic, focal 2, 616400 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001258205.1	NP_001245134.1	transient receptor potential cation channel subfamily V member 3 isoform 1
NM_001258205.2	NP_001245134.1	transient receptor potential cation channel subfamily V member 3 isoform 1
NM_145068.3	NP_659505.1	transient receptor potential cation channel subfamily V member 3 isoform 2
NM_145068.4	NP_659505.1	transient receptor potential cation channel subfamily V member 3 isoform 2

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	trpv3	NP_001243218.1
Pan troglodytes (chimpanzee)	TRPV3	XP_003952990.1
Gallus gallus (chicken)	TRPV3	XP_004946732.1
Canis lupus familiaris (dog)	TRPV3	XP_005625015.1
Homo sapiens (human)	TRPV3	NP_659505.1
Mus musculus (house mouse)	Trpv3	NP_659567.2
Rattus norvegicus (Norway rat)	Trpv3	NP_001020928.2

Gene Ontology
Bibliography

Related articles in PubMed

The human transient receptor potential vanilloid 3 channel is sensitized via the ERK pathway.
Vyklicka L, Boukalova S, Macikova L, Chvojka S, Vlachova V
The Journal of biological chemistry292(51)21083-21091(2017 Dec)

Expression and distribution of three transient receptor potential vanilloid(TRPV) channel proteins in human odontoblast-like cells.
Wen W, Que K, Zang C, Wen J, Sun G, Zhao Z, Li Y
Journal of molecular histology48(5-6)367-377(2017 Dec)

TRPV3 Channel in Keratinocytes in Scars with Post-Burn Pruritus.
Park CW, Kim HJ, Choi YW, Chung BY, Woo SY, Song DK, Kim HO
International journal of molecular sciences18(11)(2017 Nov)

Activation of TRPV3 Regulates Inflammatory Actions of Human Epidermal Keratinocytes.
Sz?ll?si AG, Vasas N, Angyal ?, Kistam?s K, N?n?si PP, Mih?ly J, B?ke G, Herczeg-Lisztes E, Szegedi A, Kawada N, Yanagida T, Mori T, Kem?ny L, B?r? T
The Journal of investigative dermatology(2017 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TRPV3 mutants causing Olmsted Syndrome induce impaired cell adhesion and nonfunctional lysosomes
Title: TRPV3 mutants causing Olmsted Syndrome induce impaired cell adhesion and nonfunctional lysosomes.

The results of the present study show that polymorphism of TRPV3 contributed towards symptom severity in FM.
Title: Polymorphisms of the TRPV2 and TRPV3 genes associated with fibromyalgia in a Korean population.

*We describe two cases of Olmsted-like syndrome in a Mongolian family. *The underlying cause was a previously undescribed G573V point mutation in TRPV3.
Title: Two familial cases of Olmsted-like syndrome with a G573V mutation of the TRPV3 gene.

High Transient receptor potential vanilloid 3 protein expression could promote the proliferation of lung cancer cells. Transient receptor potential vanilloid 3 inhibition decreased [Ca2+]i of lung cancer cells and cell cycle arrest at the G1/S boundary.
Title: Overexpression of TRPV3 Correlates with Tumor Progression in Non-Small Cell Lung Cancer.

A novel mutation in TRPV3 gene causes atypical familial Olmsted syndrome in a Chinese family.
Title: A novel mutation in TRPV3 gene causes atypical familial Olmsted syndrome.

The following TRPV3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TRPV3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu21719	NM_001258205.2 Latest version!	Homo sapiens transient receptor potential cation channel subfamily V member 3 (TRPV3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu27629	NM_145068.4 Latest version!	Homo sapiens transient receptor potential cation channel subfamily V member 3 (TRPV3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu21719	NM_001258205.1	Homo sapiens transient receptor potential cation channel subfamily V member 3 (TRPV3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu27629	NM_145068.3	Homo sapiens transient receptor potential cation channel subfamily V member 3 (TRPV3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TRPV3 ( NM_001258205.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001245134.1 Homo sapiens transient receptor potential cation channel subfamily V member 3 (TRPV3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21719
Clone ID Related Accession (Same CDS sequence)	NM_001258205.1 , NM_001258205.2
Accession Version	NM_001258205.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2376bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	transient receptor potential cation channel subfamily V member 3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC027796.9, EU295940.1, AC025125.15 and BX537539.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY118268.1, BC104866.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAAGCCC ACCCCAAGGA GATGGTGCCT CTCATGGGCA AGAGAGTTGC TGCCCCCAGT 
GGGAACCCTG CCATCCTGCC AGAGAAGAGG CCGGCGGAGA TCACCCCCAC AAAGAAGAGT 
GCACACTTCT TCCTGGAGAT AGAAGGGTTT GAACCCAACC CCACAGTTGC CAAGACCTCT 
CCTCCTGTCT TCTCCAAGCC CATGGATTCC AACATCCGGC AGTGCATCTC TGGTAACTGT 
GATGACATGG ACTCCCCCCA GTCTCCTCAG GATGATGTGA CAGAGACCCC ATCCAATCCC 
AACAGCCCCA GTGCACAGCT GGCCAAGGAA GAGCAGAGGA GGAAAAAGAG GCGGCTGAAG 
AAGCGCATCT TTGCAGCCGT GTCTGAGGGC TGCGTGGAGG AGTTGGTAGA GTTGCTGGTG 
GAGCTGCAGG AGCTTTGCAG GCGGCGCCAT GATGAGGATG TGCCTGACTT CCTCATGCAC 
AAGCTGACGG CCTCCGACAC GGGGAAGACC TGCCTGATGA AGGCCTTGTT AAACATCAAC 
CCCAACACCA AGGAGATAGT GCGGATCCTG CTTGCCTTTG CTGAAGAGAA CGACATCCTG 
GGCAGGTTCA TCAACGCCGA GTACACAGAG GAGGCCTATG AAGGGCAGAC GGCGCTGAAC 
ATCGCCATCG AGCGGCGGCA GGGGGACATC GCAGCCCTGC TCATCGCCGC CGGCGCCGAC 
GTCAACGCGC ACGCCAAGGG GGCCTTCTTC AACCCCAAGT ACCAACACGA AGGCTTCTAC 
TTCGGTGAGA CGCCCCTGGC CCTGGCAGCA TGCACCAACC AGCCCGAGAT TGTGCAGCTG 
CTGATGGAGC ACGAGCAGAC GGACATCACC TCGCGGGACT CACGAGGCAA CAACATCCTT 
CACGCCCTGG TGACCGTGGC CGAGGACTTC AAGACGCAGA ATGACTTTGT GAAGCGCATG 
TACGACATGA TCCTACTGCG GAGTGGCAAC TGGGAGCTGG AGACCACTCG CAACAACGAT 
GGCCTCACGC CGCTGCAGCT GGCCGCCAAG ATGGGCAAGG CGGAGATCCT GAAGTACATC 
CTCAGTCGTG AGATCAAGGA GAAGCGGCTC CGGAGCCTGT CCAGGAAGTT CACCGACTGG 
GCGTACGGAC CCGTGTCATC CTCCCTCTAC GACCTCACCA ACGTGGACAC CACCACGGAC 
AACTCAGTGC TGGAAATCAC TGTCTACAAC ACCAACATCG ACAACCGGCA TGAGATGCTG 
ACCCTGGAGC CGCTGCACAC GCTGCTGCAT ATGAAGTGGA AGAAGTTTGC CAAGCACATG 
TTCTTTCTGT CCTTCTGCTT TTATTTCTTC TACAACATCA CCCTGACCCT CGTCTCGTAC 
TACCGCCCCC GGGAGGAGGA GGCCATCCCG CACCCCTTGG CCCTGACGCA CAAGATGGGG 
TGGCTGCAGC TCCTAGGGAG GATGTTTGTG CTCATCTGGG CCATGTGCAT CTCTGTGAAA 
GAGGGCATTG CCATCTTCCT GCTGAGACCC TCGGATCTGC AGTCCATCCT CTCGGATGCC 
TGGTTCCACT TTGTCTTTTT TATCCAAGCT GTGCTTGTGA TACTGTCTGT CTTCTTGTAC 
TTGTTTGCCT ACAAAGAGTA CCTCGCCTGC CTCGTGCTGG CCATGGCCCT GGGCTGGGCG 
AACATGCTCT ACTATACGCG GGGTTTCCAG TCCATGGGCA TGTACAGCGT CATGATCCAG 
AAGGTCATTT TGCATGATGT TCTGAAGTTC TTGTTTGTAT ATATCGTGTT TTTGCTTGGA 
TTTGGAGTAG CCTTGGCCTC GCTGATCGAG AAGTGTCCCA AAGACAACAA GGACTGCAGC 
TCCTACGGCA GCTTCAGCGA CGCAGTGCTG GAACTCTTCA AGCTCACCAT AGGCCTGGGT 
GACCTGAACA TCCAGCAGAA CTCCAAGTAT CCCATTCTCT TTCTGTTCCT GCTCATCACC 
TATGTCATCC TCACCTTTGT TCTCCTCCTC AACATGCTCA TTGCTCTGAT GGGCGAGACT 
GTGGAGAACG TCTCCAAGGA GAGCGAACGC ATCTGGCGCC TGCAGAGAGC CAGGACCATC 
TTGGAGTTTG AGAAAATGTT ACCAGAATGG CTGAGGAGCA GATTCCGGAT GGGAGAGCTG 
TGCAAAGTGG CCGAGGATGA TTTCCGACTG TGTTTGCGGA TCAATGAGGT GAAGTGGACT 
GAATGGAAGA CGCACGTCTC CTTCCTTAAC GAAGACCCGG GGCCTGTAAG ACGAACAGCA 
GATTTCAACA AAATCCAAGA TTCTTCCAGG AACAACAGCA AAACCACTCT CAATGCATTT 
GAAGAAGTCG AGGAATTCCC GGAAACCTCG GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001245134.1
CDS	323..2698
Translation	MKAHPKEMVPLMGKRVAAPSGNPAILPEKRPAEITPTKKSAHFFLEIEGFEPNPTVAKTSPPVFSKPMDSNIRQCISGNCDDMDSPQSPQDDVTETPSNPNSPSAQLAKEEQRRKKRRLKKRIFAAVSEGCVEELVELLVELQELCRRRHDEDVPDFLMHKLTASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILGRFINAEYTEEAYEGQTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYILSREIKEKRLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDNSVLEITVYNTNIDNRHEMLTLEPLHTLLHMKWKKFAKHMFFLSFCFYFFYNITLTLVSYYRPREEEAIPHPLALTHKMGWLQLLGRMFVLIWAMCISVKEGIAIFLLRPSDLQSILSDAWFHFVFFIQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYIVFLLGFGVALASLIEKCPKDNKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSKYPILFLFLLITYVILTFVLLLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPEWLRSRFRMGELCKVAEDDFRLCLRINEVKWTEWKTHVSFLNEDPGPVRRTADFNKIQDSSRNNSKTTLNAFEEVEEFPETSV

Target ORF information:

RefSeq Version	NM_001258205.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transient receptor potential cation channel subfamily V member 3 (TRPV3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001258205.1

ORF Insert Sequence:

ATGAAAGCCC ACCCCAAGGA GATGGTGCCT CTCATGGGCA AGAGAGTTGC TGCCCCCAGT 
GGGAACCCTG CCATCCTGCC AGAGAAGAGG CCGGCGGAGA TCACCCCCAC AAAGAAGAGT 
GCACACTTCT TCCTGGAGAT AGAAGGGTTT GAACCCAACC CCACAGTTGC CAAGACCTCT 
CCTCCTGTCT TCTCCAAGCC CATGGATTCC AACATCCGGC AGTGCATCTC TGGTAACTGT 
GATGACATGG ACTCCCCCCA GTCTCCTCAG GATGATGTGA CAGAGACCCC ATCCAATCCC 
AACAGCCCCA GTGCACAGCT GGCCAAGGAA GAGCAGAGGA GGAAAAAGAG GCGGCTGAAG 
AAGCGCATCT TTGCAGCCGT GTCTGAGGGC TGCGTGGAGG AGTTGGTAGA GTTGCTGGTG 
GAGCTGCAGG AGCTTTGCAG GCGGCGCCAT GATGAGGATG TGCCTGACTT CCTCATGCAC 
AAGCTGACGG CCTCCGACAC GGGGAAGACC TGCCTGATGA AGGCCTTGTT AAACATCAAC 
CCCAACACCA AGGAGATAGT GCGGATCCTG CTTGCCTTTG CTGAAGAGAA CGACATCCTG 
GGCAGGTTCA TCAACGCCGA GTACACAGAG GAGGCCTATG AAGGGCAGAC GGCGCTGAAC 
ATCGCCATCG AGCGGCGGCA GGGGGACATC GCAGCCCTGC TCATCGCCGC CGGCGCCGAC 
GTCAACGCGC ACGCCAAGGG GGCCTTCTTC AACCCCAAGT ACCAACACGA AGGCTTCTAC 
TTCGGTGAGA CGCCCCTGGC CCTGGCAGCA TGCACCAACC AGCCCGAGAT TGTGCAGCTG 
CTGATGGAGC ACGAGCAGAC GGACATCACC TCGCGGGACT CACGAGGCAA CAACATCCTT 
CACGCCCTGG TGACCGTGGC CGAGGACTTC AAGACGCAGA ATGACTTTGT GAAGCGCATG 
TACGACATGA TCCTACTGCG GAGTGGCAAC TGGGAGCTGG AGACCACTCG CAACAACGAT 
GGCCTCACGC CGCTGCAGCT GGCCGCCAAG ATGGGCAAGG CGGAGATCCT GAAGTACATC 
CTCAGTCGTG AGATCAAGGA GAAGCGGCTC CGGAGCCTGT CCAGGAAGTT CACCGACTGG 
GCGTACGGAC CCGTGTCATC CTCCCTCTAC GACCTCACCA ACGTGGACAC CACCACGGAC 
AACTCAGTGC TGGAAATCAC TGTCTACAAC ACCAACATCG ACAACCGGCA TGAGATGCTG 
ACCCTGGAGC CGCTGCACAC GCTGCTGCAT ATGAAGTGGA AGAAGTTTGC CAAGCACATG 
TTCTTTCTGT CCTTCTGCTT TTATTTCTTC TACAACATCA CCCTGACCCT CGTCTCGTAC 
TACCGCCCCC GGGAGGAGGA GGCCATCCCG CACCCCTTGG CCCTGACGCA CAAGATGGGG 
TGGCTGCAGC TCCTAGGGAG GATGTTTGTG CTCATCTGGG CCATGTGCAT CTCTGTGAAA 
GAGGGCATTG CCATCTTCCT GCTGAGACCC TCGGATCTGC AGTCCATCCT CTCGGATGCC 
TGGTTCCACT TTGTCTTTTT TATCCAAGCT GTGCTTGTGA TACTGTCTGT CTTCTTGTAC 
TTGTTTGCCT ACAAAGAGTA CCTCGCCTGC CTCGTGCTGG CCATGGCCCT GGGCTGGGCG 
AACATGCTCT ACTATACGCG GGGTTTCCAG TCCATGGGCA TGTACAGCGT CATGATCCAG 
AAGGTCATTT TGCATGATGT TCTGAAGTTC TTGTTTGTAT ATATCGTGTT TTTGCTTGGA 
TTTGGAGTAG CCTTGGCCTC GCTGATCGAG AAGTGTCCCA AAGACAACAA GGACTGCAGC 
TCCTACGGCA GCTTCAGCGA CGCAGTGCTG GAACTCTTCA AGCTCACCAT AGGCCTGGGT 
GACCTGAACA TCCAGCAGAA CTCCAAGTAT CCCATTCTCT TTCTGTTCCT GCTCATCACC 
TATGTCATCC TCACCTTTGT TCTCCTCCTC AACATGCTCA TTGCTCTGAT GGGCGAGACT 
GTGGAGAACG TCTCCAAGGA GAGCGAACGC ATCTGGCGCC TGCAGAGAGC CAGGACCATC 
TTGGAGTTTG AGAAAATGTT ACCAGAATGG CTGAGGAGCA GATTCCGGAT GGGAGAGCTG 
TGCAAAGTGG CCGAGGATGA TTTCCGACTG TGTTTGCGGA TCAATGAGGT GAAGTGGACT 
GAATGGAAGA CGCACGTCTC CTTCCTTAAC GAAGACCCGG GGCCTGTAAG ACGAACAGCA 
GATTTCAACA AAATCCAAGA TTCTTCCAGG AACAACAGCA AAACCACTCT CAATGCATTT 
GAAGAAGTCG AGGAATTCCC GGAAACCTCG GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRPV3 ( NM_001258205.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001245134.1 Homo sapiens transient receptor potential cation channel subfamily V member 3 (TRPV3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21719
Clone ID Related Accession (Same CDS sequence)	NM_001258205.1 , NM_001258205.2
Accession Version	NM_001258205.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2376bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-01
Organism	Homo sapiens(human)
Product	transient receptor potential cation channel subfamily V member 3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC027796.9, EU295940.1, AC025125.15 and BX537539.1. On Jun 2, 2019 this sequence version replaced NM_001258205.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY118268.1, BC143330.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAAGCCC ACCCCAAGGA GATGGTGCCT CTCATGGGCA AGAGAGTTGC TGCCCCCAGT 
GGGAACCCTG CCATCCTGCC AGAGAAGAGG CCGGCGGAGA TCACCCCCAC AAAGAAGAGT 
GCACACTTCT TCCTGGAGAT AGAAGGGTTT GAACCCAACC CCACAGTTGC CAAGACCTCT 
CCTCCTGTCT TCTCCAAGCC CATGGATTCC AACATCCGGC AGTGCATCTC TGGTAACTGT 
GATGACATGG ACTCCCCCCA GTCTCCTCAG GATGATGTGA CAGAGACCCC ATCCAATCCC 
AACAGCCCCA GTGCACAGCT GGCCAAGGAA GAGCAGAGGA GGAAAAAGAG GCGGCTGAAG 
AAGCGCATCT TTGCAGCCGT GTCTGAGGGC TGCGTGGAGG AGTTGGTAGA GTTGCTGGTG 
GAGCTGCAGG AGCTTTGCAG GCGGCGCCAT GATGAGGATG TGCCTGACTT CCTCATGCAC 
AAGCTGACGG CCTCCGACAC GGGGAAGACC TGCCTGATGA AGGCCTTGTT AAACATCAAC 
CCCAACACCA AGGAGATAGT GCGGATCCTG CTTGCCTTTG CTGAAGAGAA CGACATCCTG 
GGCAGGTTCA TCAACGCCGA GTACACAGAG GAGGCCTATG AAGGGCAGAC GGCGCTGAAC 
ATCGCCATCG AGCGGCGGCA GGGGGACATC GCAGCCCTGC TCATCGCCGC CGGCGCCGAC 
GTCAACGCGC ACGCCAAGGG GGCCTTCTTC AACCCCAAGT ACCAACACGA AGGCTTCTAC 
TTCGGTGAGA CGCCCCTGGC CCTGGCAGCA TGCACCAACC AGCCCGAGAT TGTGCAGCTG 
CTGATGGAGC ACGAGCAGAC GGACATCACC TCGCGGGACT CACGAGGCAA CAACATCCTT 
CACGCCCTGG TGACCGTGGC CGAGGACTTC AAGACGCAGA ATGACTTTGT GAAGCGCATG 
TACGACATGA TCCTACTGCG GAGTGGCAAC TGGGAGCTGG AGACCACTCG CAACAACGAT 
GGCCTCACGC CGCTGCAGCT GGCCGCCAAG ATGGGCAAGG CGGAGATCCT GAAGTACATC 
CTCAGTCGTG AGATCAAGGA GAAGCGGCTC CGGAGCCTGT CCAGGAAGTT CACCGACTGG 
GCGTACGGAC CCGTGTCATC CTCCCTCTAC GACCTCACCA ACGTGGACAC CACCACGGAC 
AACTCAGTGC TGGAAATCAC TGTCTACAAC ACCAACATCG ACAACCGGCA TGAGATGCTG 
ACCCTGGAGC CGCTGCACAC GCTGCTGCAT ATGAAGTGGA AGAAGTTTGC CAAGCACATG 
TTCTTTCTGT CCTTCTGCTT TTATTTCTTC TACAACATCA CCCTGACCCT CGTCTCGTAC 
TACCGCCCCC GGGAGGAGGA GGCCATCCCG CACCCCTTGG CCCTGACGCA CAAGATGGGG 
TGGCTGCAGC TCCTAGGGAG GATGTTTGTG CTCATCTGGG CCATGTGCAT CTCTGTGAAA 
GAGGGCATTG CCATCTTCCT GCTGAGACCC TCGGATCTGC AGTCCATCCT CTCGGATGCC 
TGGTTCCACT TTGTCTTTTT TATCCAAGCT GTGCTTGTGA TACTGTCTGT CTTCTTGTAC 
TTGTTTGCCT ACAAAGAGTA CCTCGCCTGC CTCGTGCTGG CCATGGCCCT GGGCTGGGCG 
AACATGCTCT ACTATACGCG GGGTTTCCAG TCCATGGGCA TGTACAGCGT CATGATCCAG 
AAGGTCATTT TGCATGATGT TCTGAAGTTC TTGTTTGTAT ATATCGTGTT TTTGCTTGGA 
TTTGGAGTAG CCTTGGCCTC GCTGATCGAG AAGTGTCCCA AAGACAACAA GGACTGCAGC 
TCCTACGGCA GCTTCAGCGA CGCAGTGCTG GAACTCTTCA AGCTCACCAT AGGCCTGGGT 
GACCTGAACA TCCAGCAGAA CTCCAAGTAT CCCATTCTCT TTCTGTTCCT GCTCATCACC 
TATGTCATCC TCACCTTTGT TCTCCTCCTC AACATGCTCA TTGCTCTGAT GGGCGAGACT 
GTGGAGAACG TCTCCAAGGA GAGCGAACGC ATCTGGCGCC TGCAGAGAGC CAGGACCATC 
TTGGAGTTTG AGAAAATGTT ACCAGAATGG CTGAGGAGCA GATTCCGGAT GGGAGAGCTG 
TGCAAAGTGG CCGAGGATGA TTTCCGACTG TGTTTGCGGA TCAATGAGGT GAAGTGGACT 
GAATGGAAGA CGCACGTCTC CTTCCTTAAC GAAGACCCGG GGCCTGTAAG ACGAACAGCA 
GATTTCAACA AAATCCAAGA TTCTTCCAGG AACAACAGCA AAACCACTCT CAATGCATTT 
GAAGAAGTCG AGGAATTCCC GGAAACCTCG GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001245134.1
CDS	140..2515
Translation	MKAHPKEMVPLMGKRVAAPSGNPAILPEKRPAEITPTKKSAHFFLEIEGFEPNPTVAKTSPPVFSKPMDSNIRQCISGNCDDMDSPQSPQDDVTETPSNPNSPSAQLAKEEQRRKKRRLKKRIFAAVSEGCVEELVELLVELQELCRRRHDEDVPDFLMHKLTASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILGRFINAEYTEEAYEGQTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYILSREIKEKRLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDNSVLEITVYNTNIDNRHEMLTLEPLHTLLHMKWKKFAKHMFFLSFCFYFFYNITLTLVSYYRPREEEAIPHPLALTHKMGWLQLLGRMFVLIWAMCISVKEGIAIFLLRPSDLQSILSDAWFHFVFFIQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYIVFLLGFGVALASLIEKCPKDNKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSKYPILFLFLLITYVILTFVLLLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPEWLRSRFRMGELCKVAEDDFRLCLRINEVKWTEWKTHVSFLNEDPGPVRRTADFNKIQDSSRNNSKTTLNAFEEVEEFPETSV

Target ORF information:

RefSeq Version	NM_001258205.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transient receptor potential cation channel subfamily V member 3 (TRPV3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001258205.2

ORF Insert Sequence:

ATGAAAGCCC ACCCCAAGGA GATGGTGCCT CTCATGGGCA AGAGAGTTGC TGCCCCCAGT 
GGGAACCCTG CCATCCTGCC AGAGAAGAGG CCGGCGGAGA TCACCCCCAC AAAGAAGAGT 
GCACACTTCT TCCTGGAGAT AGAAGGGTTT GAACCCAACC CCACAGTTGC CAAGACCTCT 
CCTCCTGTCT TCTCCAAGCC CATGGATTCC AACATCCGGC AGTGCATCTC TGGTAACTGT 
GATGACATGG ACTCCCCCCA GTCTCCTCAG GATGATGTGA CAGAGACCCC ATCCAATCCC 
AACAGCCCCA GTGCACAGCT GGCCAAGGAA GAGCAGAGGA GGAAAAAGAG GCGGCTGAAG 
AAGCGCATCT TTGCAGCCGT GTCTGAGGGC TGCGTGGAGG AGTTGGTAGA GTTGCTGGTG 
GAGCTGCAGG AGCTTTGCAG GCGGCGCCAT GATGAGGATG TGCCTGACTT CCTCATGCAC 
AAGCTGACGG CCTCCGACAC GGGGAAGACC TGCCTGATGA AGGCCTTGTT AAACATCAAC 
CCCAACACCA AGGAGATAGT GCGGATCCTG CTTGCCTTTG CTGAAGAGAA CGACATCCTG 
GGCAGGTTCA TCAACGCCGA GTACACAGAG GAGGCCTATG AAGGGCAGAC GGCGCTGAAC 
ATCGCCATCG AGCGGCGGCA GGGGGACATC GCAGCCCTGC TCATCGCCGC CGGCGCCGAC 
GTCAACGCGC ACGCCAAGGG GGCCTTCTTC AACCCCAAGT ACCAACACGA AGGCTTCTAC 
TTCGGTGAGA CGCCCCTGGC CCTGGCAGCA TGCACCAACC AGCCCGAGAT TGTGCAGCTG 
CTGATGGAGC ACGAGCAGAC GGACATCACC TCGCGGGACT CACGAGGCAA CAACATCCTT 
CACGCCCTGG TGACCGTGGC CGAGGACTTC AAGACGCAGA ATGACTTTGT GAAGCGCATG 
TACGACATGA TCCTACTGCG GAGTGGCAAC TGGGAGCTGG AGACCACTCG CAACAACGAT 
GGCCTCACGC CGCTGCAGCT GGCCGCCAAG ATGGGCAAGG CGGAGATCCT GAAGTACATC 
CTCAGTCGTG AGATCAAGGA GAAGCGGCTC CGGAGCCTGT CCAGGAAGTT CACCGACTGG 
GCGTACGGAC CCGTGTCATC CTCCCTCTAC GACCTCACCA ACGTGGACAC CACCACGGAC 
AACTCAGTGC TGGAAATCAC TGTCTACAAC ACCAACATCG ACAACCGGCA TGAGATGCTG 
ACCCTGGAGC CGCTGCACAC GCTGCTGCAT ATGAAGTGGA AGAAGTTTGC CAAGCACATG 
TTCTTTCTGT CCTTCTGCTT TTATTTCTTC TACAACATCA CCCTGACCCT CGTCTCGTAC 
TACCGCCCCC GGGAGGAGGA GGCCATCCCG CACCCCTTGG CCCTGACGCA CAAGATGGGG 
TGGCTGCAGC TCCTAGGGAG GATGTTTGTG CTCATCTGGG CCATGTGCAT CTCTGTGAAA 
GAGGGCATTG CCATCTTCCT GCTGAGACCC TCGGATCTGC AGTCCATCCT CTCGGATGCC 
TGGTTCCACT TTGTCTTTTT TATCCAAGCT GTGCTTGTGA TACTGTCTGT CTTCTTGTAC 
TTGTTTGCCT ACAAAGAGTA CCTCGCCTGC CTCGTGCTGG CCATGGCCCT GGGCTGGGCG 
AACATGCTCT ACTATACGCG GGGTTTCCAG TCCATGGGCA TGTACAGCGT CATGATCCAG 
AAGGTCATTT TGCATGATGT TCTGAAGTTC TTGTTTGTAT ATATCGTGTT TTTGCTTGGA 
TTTGGAGTAG CCTTGGCCTC GCTGATCGAG AAGTGTCCCA AAGACAACAA GGACTGCAGC 
TCCTACGGCA GCTTCAGCGA CGCAGTGCTG GAACTCTTCA AGCTCACCAT AGGCCTGGGT 
GACCTGAACA TCCAGCAGAA CTCCAAGTAT CCCATTCTCT TTCTGTTCCT GCTCATCACC 
TATGTCATCC TCACCTTTGT TCTCCTCCTC AACATGCTCA TTGCTCTGAT GGGCGAGACT 
GTGGAGAACG TCTCCAAGGA GAGCGAACGC ATCTGGCGCC TGCAGAGAGC CAGGACCATC 
TTGGAGTTTG AGAAAATGTT ACCAGAATGG CTGAGGAGCA GATTCCGGAT GGGAGAGCTG 
TGCAAAGTGG CCGAGGATGA TTTCCGACTG TGTTTGCGGA TCAATGAGGT GAAGTGGACT 
GAATGGAAGA CGCACGTCTC CTTCCTTAAC GAAGACCCGG GGCCTGTAAG ACGAACAGCA 
GATTTCAACA AAATCCAAGA TTCTTCCAGG AACAACAGCA AAACCACTCT CAATGCATTT 
GAAGAAGTCG AGGAATTCCC GGAAACCTCG GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRPV3 ( NM_145068.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_659505.1 Homo sapiens transient receptor potential cation channel subfamily V member 3 (TRPV3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu27629
Clone ID Related Accession (Same CDS sequence)	NM_145068.3 , NM_145068.4
Accession Version	NM_145068.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2373bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	transient receptor potential cation channel subfamily V member 3 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC027796.9, AF514998.1, AC025125.15 and BX537539.1. This sequence is a reference standard in the RefSeqGene project. On Apr 19, 2012 this sequence version replaced NM_145068.2. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region compared to variant 1. The resulting protein (isoform 2) is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ487035.2, AF514998.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAAGCCC ACCCCAAGGA GATGGTGCCT CTCATGGGCA AGAGAGTTGC TGCCCCCAGT 
GGGAACCCTG CCATCCTGCC AGAGAAGAGG CCGGCGGAGA TCACCCCCAC AAAGAAGAGT 
GCACACTTCT TCCTGGAGAT AGAAGGGTTT GAACCCAACC CCACAGTTGC CAAGACCTCT 
CCTCCTGTCT TCTCCAAGCC CATGGATTCC AACATCCGGC AGTGCATCTC TGGTAACTGT 
GATGACATGG ACTCCCCCCA GTCTCCTCAG GATGATGTGA CAGAGACCCC ATCCAATCCC 
AACAGCCCCA GTGCACAGCT GGCCAAGGAA GAGCAGAGGA GGAAAAAGAG GCGGCTGAAG 
AAGCGCATCT TTGCAGCCGT GTCTGAGGGC TGCGTGGAGG AGTTGGTAGA GTTGCTGGTG 
GAGCTGCAGG AGCTTTGCAG GCGGCGCCAT GATGAGGATG TGCCTGACTT CCTCATGCAC 
AAGCTGACGG CCTCCGACAC GGGGAAGACC TGCCTGATGA AGGCCTTGTT AAACATCAAC 
CCCAACACCA AGGAGATAGT GCGGATCCTG CTTGCCTTTG CTGAAGAGAA CGACATCCTG 
GGCAGGTTCA TCAACGCCGA GTACACAGAG GAGGCCTATG AAGGGCAGAC GGCGCTGAAC 
ATCGCCATCG AGCGGCGGCA GGGGGACATC GCAGCCCTGC TCATCGCCGC CGGCGCCGAC 
GTCAACGCGC ACGCCAAGGG GGCCTTCTTC AACCCCAAGT ACCAACACGA AGGCTTCTAC 
TTCGGTGAGA CGCCCCTGGC CCTGGCAGCA TGCACCAACC AGCCCGAGAT TGTGCAGCTG 
CTGATGGAGC ACGAGCAGAC GGACATCACC TCGCGGGACT CACGAGGCAA CAACATCCTT 
CACGCCCTGG TGACCGTGGC CGAGGACTTC AAGACGCAGA ATGACTTTGT GAAGCGCATG 
TACGACATGA TCCTACTGCG GAGTGGCAAC TGGGAGCTGG AGACCACTCG CAACAACGAT 
GGCCTCACGC CGCTGCAGCT GGCCGCCAAG ATGGGCAAGG CGGAGATCCT GAAGTACATC 
CTCAGTCGTG AGATCAAGGA GAAGCGGCTC CGGAGCCTGT CCAGGAAGTT CACCGACTGG 
GCGTACGGAC CCGTGTCATC CTCCCTCTAC GACCTCACCA ACGTGGACAC CACCACGGAC 
AACTCAGTGC TGGAAATCAC TGTCTACAAC ACCAACATCG ACAACCGGCA TGAGATGCTG 
ACCCTGGAGC CGCTGCACAC GCTGCTGCAT ATGAAGTGGA AGAAGTTTGC CAAGCACATG 
TTCTTTCTGT CCTTCTGCTT TTATTTCTTC TACAACATCA CCCTGACCCT CGTCTCGTAC 
TACCGCCCCC GGGAGGAGGA GGCCATCCCG CACCCCTTGG CCCTGACGCA CAAGATGGGG 
TGGCTGCAGC TCCTAGGGAG GATGTTTGTG CTCATCTGGG CCATGTGCAT CTCTGTGAAA 
GAGGGCATTG CCATCTTCCT GCTGAGACCC TCGGATCTGC AGTCCATCCT CTCGGATGCC 
TGGTTCCACT TTGTCTTTTT TATCCAAGCT GTGCTTGTGA TACTGTCTGT CTTCTTGTAC 
TTGTTTGCCT ACAAAGAGTA CCTCGCCTGC CTCGTGCTGG CCATGGCCCT GGGCTGGGCG 
AACATGCTCT ACTATACGCG GGGTTTCCAG TCCATGGGCA TGTACAGCGT CATGATCCAG 
AAGGTCATTT TGCATGATGT TCTGAAGTTC TTGTTTGTAT ATATCGTGTT TTTGCTTGGA 
TTTGGAGTAG CCTTGGCCTC GCTGATCGAG AAGTGTCCCA AAGACAACAA GGACTGCAGC 
TCCTACGGCA GCTTCAGCGA CGCAGTGCTG GAACTCTTCA AGCTCACCAT AGGCCTGGGT 
GACCTGAACA TCCAGCAGAA CTCCAAGTAT CCCATTCTCT TTCTGTTCCT GCTCATCACC 
TATGTCATCC TCACCTTTGT TCTCCTCCTC AACATGCTCA TTGCTCTGAT GGGCGAGACT 
GTGGAGAACG TCTCCAAGGA GAGCGAACGC ATCTGGCGCC TGCAGAGAGC CAGGACCATC 
TTGGAGTTTG AGAAAATGTT ACCAGAATGG CTGAGGAGCA GATTCCGGAT GGGAGAGCTG 
TGCAAAGTGG CCGAGGATGA TTTCCGACTG TGTTTGCGGA TCAATGAGGT GAAGTGGACT 
GAATGGAAGA CGCACGTCTC CTTCCTTAAC GAAGACCCGG GGCCTGTAAG ACGAACAGAT 
TTCAACAAAA TCCAAGATTC TTCCAGGAAC AACAGCAAAA CCACTCTCAA TGCATTTGAA 
GAAGTCGAGG AATTCCCGGA AACCTCGGTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_659505.1
CDS	323..2695
Translation	MKAHPKEMVPLMGKRVAAPSGNPAILPEKRPAEITPTKKSAHFFLEIEGFEPNPTVAKTSPPVFSKPMDSNIRQCISGNCDDMDSPQSPQDDVTETPSNPNSPSAQLAKEEQRRKKRRLKKRIFAAVSEGCVEELVELLVELQELCRRRHDEDVPDFLMHKLTASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILGRFINAEYTEEAYEGQTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYILSREIKEKRLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDNSVLEITVYNTNIDNRHEMLTLEPLHTLLHMKWKKFAKHMFFLSFCFYFFYNITLTLVSYYRPREEEAIPHPLALTHKMGWLQLLGRMFVLIWAMCISVKEGIAIFLLRPSDLQSILSDAWFHFVFFIQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYIVFLLGFGVALASLIEKCPKDNKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSKYPILFLFLLITYVILTFVLLLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPEWLRSRFRMGELCKVAEDDFRLCLRINEVKWTEWKTHVSFLNEDPGPVRRTDFNKIQDSSRNNSKTTLNAFEEVEEFPETSV

Target ORF information:

RefSeq Version	NM_145068.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transient receptor potential cation channel subfamily V member 3 (TRPV3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145068.3

ORF Insert Sequence:

ATGAAAGCCC ACCCCAAGGA GATGGTGCCT CTCATGGGCA AGAGAGTTGC TGCCCCCAGT 
GGGAACCCTG CCATCCTGCC AGAGAAGAGG CCGGCGGAGA TCACCCCCAC AAAGAAGAGT 
GCACACTTCT TCCTGGAGAT AGAAGGGTTT GAACCCAACC CCACAGTTGC CAAGACCTCT 
CCTCCTGTCT TCTCCAAGCC CATGGATTCC AACATCCGGC AGTGCATCTC TGGTAACTGT 
GATGACATGG ACTCCCCCCA GTCTCCTCAG GATGATGTGA CAGAGACCCC ATCCAATCCC 
AACAGCCCCA GTGCACAGCT GGCCAAGGAA GAGCAGAGGA GGAAAAAGAG GCGGCTGAAG 
AAGCGCATCT TTGCAGCCGT GTCTGAGGGC TGCGTGGAGG AGTTGGTAGA GTTGCTGGTG 
GAGCTGCAGG AGCTTTGCAG GCGGCGCCAT GATGAGGATG TGCCTGACTT CCTCATGCAC 
AAGCTGACGG CCTCCGACAC GGGGAAGACC TGCCTGATGA AGGCCTTGTT AAACATCAAC 
CCCAACACCA AGGAGATAGT GCGGATCCTG CTTGCCTTTG CTGAAGAGAA CGACATCCTG 
GGCAGGTTCA TCAACGCCGA GTACACAGAG GAGGCCTATG AAGGGCAGAC GGCGCTGAAC 
ATCGCCATCG AGCGGCGGCA GGGGGACATC GCAGCCCTGC TCATCGCCGC CGGCGCCGAC 
GTCAACGCGC ACGCCAAGGG GGCCTTCTTC AACCCCAAGT ACCAACACGA AGGCTTCTAC 
TTCGGTGAGA CGCCCCTGGC CCTGGCAGCA TGCACCAACC AGCCCGAGAT TGTGCAGCTG 
CTGATGGAGC ACGAGCAGAC GGACATCACC TCGCGGGACT CACGAGGCAA CAACATCCTT 
CACGCCCTGG TGACCGTGGC CGAGGACTTC AAGACGCAGA ATGACTTTGT GAAGCGCATG 
TACGACATGA TCCTACTGCG GAGTGGCAAC TGGGAGCTGG AGACCACTCG CAACAACGAT 
GGCCTCACGC CGCTGCAGCT GGCCGCCAAG ATGGGCAAGG CGGAGATCCT GAAGTACATC 
CTCAGTCGTG AGATCAAGGA GAAGCGGCTC CGGAGCCTGT CCAGGAAGTT CACCGACTGG 
GCGTACGGAC CCGTGTCATC CTCCCTCTAC GACCTCACCA ACGTGGACAC CACCACGGAC 
AACTCAGTGC TGGAAATCAC TGTCTACAAC ACCAACATCG ACAACCGGCA TGAGATGCTG 
ACCCTGGAGC CGCTGCACAC GCTGCTGCAT ATGAAGTGGA AGAAGTTTGC CAAGCACATG 
TTCTTTCTGT CCTTCTGCTT TTATTTCTTC TACAACATCA CCCTGACCCT CGTCTCGTAC 
TACCGCCCCC GGGAGGAGGA GGCCATCCCG CACCCCTTGG CCCTGACGCA CAAGATGGGG 
TGGCTGCAGC TCCTAGGGAG GATGTTTGTG CTCATCTGGG CCATGTGCAT CTCTGTGAAA 
GAGGGCATTG CCATCTTCCT GCTGAGACCC TCGGATCTGC AGTCCATCCT CTCGGATGCC 
TGGTTCCACT TTGTCTTTTT TATCCAAGCT GTGCTTGTGA TACTGTCTGT CTTCTTGTAC 
TTGTTTGCCT ACAAAGAGTA CCTCGCCTGC CTCGTGCTGG CCATGGCCCT GGGCTGGGCG 
AACATGCTCT ACTATACGCG GGGTTTCCAG TCCATGGGCA TGTACAGCGT CATGATCCAG 
AAGGTCATTT TGCATGATGT TCTGAAGTTC TTGTTTGTAT ATATCGTGTT TTTGCTTGGA 
TTTGGAGTAG CCTTGGCCTC GCTGATCGAG AAGTGTCCCA AAGACAACAA GGACTGCAGC 
TCCTACGGCA GCTTCAGCGA CGCAGTGCTG GAACTCTTCA AGCTCACCAT AGGCCTGGGT 
GACCTGAACA TCCAGCAGAA CTCCAAGTAT CCCATTCTCT TTCTGTTCCT GCTCATCACC 
TATGTCATCC TCACCTTTGT TCTCCTCCTC AACATGCTCA TTGCTCTGAT GGGCGAGACT 
GTGGAGAACG TCTCCAAGGA GAGCGAACGC ATCTGGCGCC TGCAGAGAGC CAGGACCATC 
TTGGAGTTTG AGAAAATGTT ACCAGAATGG CTGAGGAGCA GATTCCGGAT GGGAGAGCTG 
TGCAAAGTGG CCGAGGATGA TTTCCGACTG TGTTTGCGGA TCAATGAGGT GAAGTGGACT 
GAATGGAAGA CGCACGTCTC CTTCCTTAAC GAAGACCCGG GGCCTGTAAG ACGAACAGAT 
TTCAACAAAA TCCAAGATTC TTCCAGGAAC AACAGCAAAA CCACTCTCAA TGCATTTGAA 
GAAGTCGAGG AATTCCCGGA AACCTCGGTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRPV3 ( NM_145068.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_659505.1 Homo sapiens transient receptor potential cation channel subfamily V member 3 (TRPV3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu27629
Clone ID Related Accession (Same CDS sequence)	NM_145068.3 , NM_145068.4
Accession Version	NM_145068.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2373bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	transient receptor potential cation channel subfamily V member 3 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC027796.9, AF514998.1, AC025125.15 and BX537539.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_145068.3. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region compared to variant 1. The resulting protein (isoform 2) is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF514998.1, AJ487035.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAAAGCCC ACCCCAAGGA GATGGTGCCT CTCATGGGCA AGAGAGTTGC TGCCCCCAGT 
GGGAACCCTG CCATCCTGCC AGAGAAGAGG CCGGCGGAGA TCACCCCCAC AAAGAAGAGT 
GCACACTTCT TCCTGGAGAT AGAAGGGTTT GAACCCAACC CCACAGTTGC CAAGACCTCT 
CCTCCTGTCT TCTCCAAGCC CATGGATTCC AACATCCGGC AGTGCATCTC TGGTAACTGT 
GATGACATGG ACTCCCCCCA GTCTCCTCAG GATGATGTGA CAGAGACCCC ATCCAATCCC 
AACAGCCCCA GTGCACAGCT GGCCAAGGAA GAGCAGAGGA GGAAAAAGAG GCGGCTGAAG 
AAGCGCATCT TTGCAGCCGT GTCTGAGGGC TGCGTGGAGG AGTTGGTAGA GTTGCTGGTG 
GAGCTGCAGG AGCTTTGCAG GCGGCGCCAT GATGAGGATG TGCCTGACTT CCTCATGCAC 
AAGCTGACGG CCTCCGACAC GGGGAAGACC TGCCTGATGA AGGCCTTGTT AAACATCAAC 
CCCAACACCA AGGAGATAGT GCGGATCCTG CTTGCCTTTG CTGAAGAGAA CGACATCCTG 
GGCAGGTTCA TCAACGCCGA GTACACAGAG GAGGCCTATG AAGGGCAGAC GGCGCTGAAC 
ATCGCCATCG AGCGGCGGCA GGGGGACATC GCAGCCCTGC TCATCGCCGC CGGCGCCGAC 
GTCAACGCGC ACGCCAAGGG GGCCTTCTTC AACCCCAAGT ACCAACACGA AGGCTTCTAC 
TTCGGTGAGA CGCCCCTGGC CCTGGCAGCA TGCACCAACC AGCCCGAGAT TGTGCAGCTG 
CTGATGGAGC ACGAGCAGAC GGACATCACC TCGCGGGACT CACGAGGCAA CAACATCCTT 
CACGCCCTGG TGACCGTGGC CGAGGACTTC AAGACGCAGA ATGACTTTGT GAAGCGCATG 
TACGACATGA TCCTACTGCG GAGTGGCAAC TGGGAGCTGG AGACCACTCG CAACAACGAT 
GGCCTCACGC CGCTGCAGCT GGCCGCCAAG ATGGGCAAGG CGGAGATCCT GAAGTACATC 
CTCAGTCGTG AGATCAAGGA GAAGCGGCTC CGGAGCCTGT CCAGGAAGTT CACCGACTGG 
GCGTACGGAC CCGTGTCATC CTCCCTCTAC GACCTCACCA ACGTGGACAC CACCACGGAC 
AACTCAGTGC TGGAAATCAC TGTCTACAAC ACCAACATCG ACAACCGGCA TGAGATGCTG 
ACCCTGGAGC CGCTGCACAC GCTGCTGCAT ATGAAGTGGA AGAAGTTTGC CAAGCACATG 
TTCTTTCTGT CCTTCTGCTT TTATTTCTTC TACAACATCA CCCTGACCCT CGTCTCGTAC 
TACCGCCCCC GGGAGGAGGA GGCCATCCCG CACCCCTTGG CCCTGACGCA CAAGATGGGG 
TGGCTGCAGC TCCTAGGGAG GATGTTTGTG CTCATCTGGG CCATGTGCAT CTCTGTGAAA 
GAGGGCATTG CCATCTTCCT GCTGAGACCC TCGGATCTGC AGTCCATCCT CTCGGATGCC 
TGGTTCCACT TTGTCTTTTT TATCCAAGCT GTGCTTGTGA TACTGTCTGT CTTCTTGTAC 
TTGTTTGCCT ACAAAGAGTA CCTCGCCTGC CTCGTGCTGG CCATGGCCCT GGGCTGGGCG 
AACATGCTCT ACTATACGCG GGGTTTCCAG TCCATGGGCA TGTACAGCGT CATGATCCAG 
AAGGTCATTT TGCATGATGT TCTGAAGTTC TTGTTTGTAT ATATCGTGTT TTTGCTTGGA 
TTTGGAGTAG CCTTGGCCTC GCTGATCGAG AAGTGTCCCA AAGACAACAA GGACTGCAGC 
TCCTACGGCA GCTTCAGCGA CGCAGTGCTG GAACTCTTCA AGCTCACCAT AGGCCTGGGT 
GACCTGAACA TCCAGCAGAA CTCCAAGTAT CCCATTCTCT TTCTGTTCCT GCTCATCACC 
TATGTCATCC TCACCTTTGT TCTCCTCCTC AACATGCTCA TTGCTCTGAT GGGCGAGACT 
GTGGAGAACG TCTCCAAGGA GAGCGAACGC ATCTGGCGCC TGCAGAGAGC CAGGACCATC 
TTGGAGTTTG AGAAAATGTT ACCAGAATGG CTGAGGAGCA GATTCCGGAT GGGAGAGCTG 
TGCAAAGTGG CCGAGGATGA TTTCCGACTG TGTTTGCGGA TCAATGAGGT GAAGTGGACT 
GAATGGAAGA CGCACGTCTC CTTCCTTAAC GAAGACCCGG GGCCTGTAAG ACGAACAGAT 
TTCAACAAAA TCCAAGATTC TTCCAGGAAC AACAGCAAAA CCACTCTCAA TGCATTTGAA 
GAAGTCGAGG AATTCCCGGA AACCTCGGTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_659505.1
CDS	140..2512
Translation	MKAHPKEMVPLMGKRVAAPSGNPAILPEKRPAEITPTKKSAHFFLEIEGFEPNPTVAKTSPPVFSKPMDSNIRQCISGNCDDMDSPQSPQDDVTETPSNPNSPSAQLAKEEQRRKKRRLKKRIFAAVSEGCVEELVELLVELQELCRRRHDEDVPDFLMHKLTASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILGRFINAEYTEEAYEGQTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYILSREIKEKRLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDNSVLEITVYNTNIDNRHEMLTLEPLHTLLHMKWKKFAKHMFFLSFCFYFFYNITLTLVSYYRPREEEAIPHPLALTHKMGWLQLLGRMFVLIWAMCISVKEGIAIFLLRPSDLQSILSDAWFHFVFFIQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYIVFLLGFGVALASLIEKCPKDNKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSKYPILFLFLLITYVILTFVLLLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPEWLRSRFRMGELCKVAEDDFRLCLRINEVKWTEWKTHVSFLNEDPGPVRRTDFNKIQDSSRNNSKTTLNAFEEVEEFPETSV

Target ORF information:

RefSeq Version	NM_145068.4
Organism	Homo sapiens(human)
Definition	Homo sapiens transient receptor potential cation channel subfamily V member 3 (TRPV3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145068.4

ORF Insert Sequence:

ATGAAAGCCC ACCCCAAGGA GATGGTGCCT CTCATGGGCA AGAGAGTTGC TGCCCCCAGT 
GGGAACCCTG CCATCCTGCC AGAGAAGAGG CCGGCGGAGA TCACCCCCAC AAAGAAGAGT 
GCACACTTCT TCCTGGAGAT AGAAGGGTTT GAACCCAACC CCACAGTTGC CAAGACCTCT 
CCTCCTGTCT TCTCCAAGCC CATGGATTCC AACATCCGGC AGTGCATCTC TGGTAACTGT 
GATGACATGG ACTCCCCCCA GTCTCCTCAG GATGATGTGA CAGAGACCCC ATCCAATCCC 
AACAGCCCCA GTGCACAGCT GGCCAAGGAA GAGCAGAGGA GGAAAAAGAG GCGGCTGAAG 
AAGCGCATCT TTGCAGCCGT GTCTGAGGGC TGCGTGGAGG AGTTGGTAGA GTTGCTGGTG 
GAGCTGCAGG AGCTTTGCAG GCGGCGCCAT GATGAGGATG TGCCTGACTT CCTCATGCAC 
AAGCTGACGG CCTCCGACAC GGGGAAGACC TGCCTGATGA AGGCCTTGTT AAACATCAAC 
CCCAACACCA AGGAGATAGT GCGGATCCTG CTTGCCTTTG CTGAAGAGAA CGACATCCTG 
GGCAGGTTCA TCAACGCCGA GTACACAGAG GAGGCCTATG AAGGGCAGAC GGCGCTGAAC 
ATCGCCATCG AGCGGCGGCA GGGGGACATC GCAGCCCTGC TCATCGCCGC CGGCGCCGAC 
GTCAACGCGC ACGCCAAGGG GGCCTTCTTC AACCCCAAGT ACCAACACGA AGGCTTCTAC 
TTCGGTGAGA CGCCCCTGGC CCTGGCAGCA TGCACCAACC AGCCCGAGAT TGTGCAGCTG 
CTGATGGAGC ACGAGCAGAC GGACATCACC TCGCGGGACT CACGAGGCAA CAACATCCTT 
CACGCCCTGG TGACCGTGGC CGAGGACTTC AAGACGCAGA ATGACTTTGT GAAGCGCATG 
TACGACATGA TCCTACTGCG GAGTGGCAAC TGGGAGCTGG AGACCACTCG CAACAACGAT 
GGCCTCACGC CGCTGCAGCT GGCCGCCAAG ATGGGCAAGG CGGAGATCCT GAAGTACATC 
CTCAGTCGTG AGATCAAGGA GAAGCGGCTC CGGAGCCTGT CCAGGAAGTT CACCGACTGG 
GCGTACGGAC CCGTGTCATC CTCCCTCTAC GACCTCACCA ACGTGGACAC CACCACGGAC 
AACTCAGTGC TGGAAATCAC TGTCTACAAC ACCAACATCG ACAACCGGCA TGAGATGCTG 
ACCCTGGAGC CGCTGCACAC GCTGCTGCAT ATGAAGTGGA AGAAGTTTGC CAAGCACATG 
TTCTTTCTGT CCTTCTGCTT TTATTTCTTC TACAACATCA CCCTGACCCT CGTCTCGTAC 
TACCGCCCCC GGGAGGAGGA GGCCATCCCG CACCCCTTGG CCCTGACGCA CAAGATGGGG 
TGGCTGCAGC TCCTAGGGAG GATGTTTGTG CTCATCTGGG CCATGTGCAT CTCTGTGAAA 
GAGGGCATTG CCATCTTCCT GCTGAGACCC TCGGATCTGC AGTCCATCCT CTCGGATGCC 
TGGTTCCACT TTGTCTTTTT TATCCAAGCT GTGCTTGTGA TACTGTCTGT CTTCTTGTAC 
TTGTTTGCCT ACAAAGAGTA CCTCGCCTGC CTCGTGCTGG CCATGGCCCT GGGCTGGGCG 
AACATGCTCT ACTATACGCG GGGTTTCCAG TCCATGGGCA TGTACAGCGT CATGATCCAG 
AAGGTCATTT TGCATGATGT TCTGAAGTTC TTGTTTGTAT ATATCGTGTT TTTGCTTGGA 
TTTGGAGTAG CCTTGGCCTC GCTGATCGAG AAGTGTCCCA AAGACAACAA GGACTGCAGC 
TCCTACGGCA GCTTCAGCGA CGCAGTGCTG GAACTCTTCA AGCTCACCAT AGGCCTGGGT 
GACCTGAACA TCCAGCAGAA CTCCAAGTAT CCCATTCTCT TTCTGTTCCT GCTCATCACC 
TATGTCATCC TCACCTTTGT TCTCCTCCTC AACATGCTCA TTGCTCTGAT GGGCGAGACT 
GTGGAGAACG TCTCCAAGGA GAGCGAACGC ATCTGGCGCC TGCAGAGAGC CAGGACCATC 
TTGGAGTTTG AGAAAATGTT ACCAGAATGG CTGAGGAGCA GATTCCGGAT GGGAGAGCTG 
TGCAAAGTGG CCGAGGATGA TTTCCGACTG TGTTTGCGGA TCAATGAGGT GAAGTGGACT 
GAATGGAAGA CGCACGTCTC CTTCCTTAAC GAAGACCCGG GGCCTGTAAG ACGAACAGAT 
TTCAACAAAA TCCAAGATTC TTCCAGGAAC AACAGCAAAA CCACTCTCAA TGCATTTGAA 
GAAGTCGAGG AATTCCCGGA AACCTCGGTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The human transient receptor potential vanilloid 3 channel is sensitized via the ERK pathway.
The Journal of biological chemistry292(51)21083-21091(2017 Dec)
Vyklicka L,Boukalova S,Macikova L,Chvojka S,Vlachova V

Expression and distribution of three transient receptor potential vanilloid(TRPV) channel proteins in human odontoblast-like cells.
Journal of molecular histology48(5-6)367-377(2017 Dec)
Wen W,Que K,Zang C,Wen J,Sun G,Zhao Z,Li Y

TRPV3 Channel in Keratinocytes in Scars with Post-Burn Pruritus.
International journal of molecular sciences18(11)(2017 Nov)
Park CW,Kim HJ,Choi YW,Chung BY,Woo SY,Song DK,Kim HO

Activation of TRPV3 Regulates Inflammatory Actions of Human Epidermal Keratinocytes.
The Journal of investigative dermatology(2017 Sep)
Sz?ll?si AG,Vasas N,Angyal ?,Kistam?s K,N?n?si PP,Mih?ly J,B?ke G,Herczeg-Lisztes E,Szegedi A,Kawada N,Yanagida T,Mori T,Kem?ny L,B?r? T

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TRPV3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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