IRX2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	IRX2
Entrez Gene ID	153572
Full Name	iroquois homeobox 2
Synonyms	IRXA2
General protein information	Preferred Names iroquois homeobox 2 Names iroquois-class homeodomain protein IRX-2 homeodomain protein IRXA2 iroquois homeobox protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5p15.33
Summary	IRX2 is a member of the Iroquois homeobox gene family. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos.[supplied by OMIM, Apr 2004].
Disorder MIM:	606198

mRNA and Protein(s)

mRNA	Protein	Name
XM_011513978.1	XP_011512280.1	iroquois-class homeodomain protein IRX-2 isoform X1
NM_001134222.2	NP_001127694.1	iroquois-class homeodomain protein IRX-2
XM_011513979.2	XP_011512281.1	iroquois-class homeodomain protein IRX-2 isoform X1
NM_001134222.1	NP_001127694.1	iroquois-class homeodomain protein IRX-2
XM_024454379.1	XP_024310147.1	iroquois-class homeodomain protein IRX-2 isoform X2
NM_033267.4	NP_150366.1	iroquois-class homeodomain protein IRX-2
XM_011513979.1	XP_011512281.1	iroquois-class homeodomain protein IRX-2 isoform X1
NM_033267.5	NP_150366.1	iroquois-class homeodomain protein IRX-2

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	irx2	NP_001008113.1
Canis lupus familiaris (dog)	IRX2	XP_848580.1
Homo sapiens (human)	IRX2	NP_150366.1
Pan troglodytes (chimpanzee)	IRX2	XP_526826.2
Mus musculus (house mouse)	Irx2	NP_034704.1
Gallus gallus (chicken)	IRX2	NP_001025507.1
Danio rerio (zebrafish)	irx2a	NP_957351.1
Rattus norvegicus (Norway rat)	Irx2	NP_001034594.1

Gene Ontology
Bibliography

Related articles in PubMed

Iroquois homeobox 2 suppresses cellular motility and chemokine expression in breast cancer cells.
Werner S, Stamm H, Pandjaitan M, Kemming D, Brors B, Pantel K, Wikman H
BMC cancer15896(2015 Nov)

IRX2-mediated upregulation of MMP-9 and VEGF in a PI3K/AKT-dependent manner.
Liu T, Zhou W, Cai B, Chu J, Shi G, Teng H, Xu J, Xiao J, Wang Y
Molecular medicine reports12(3)4346-51(2015 Sep)

Genome-wide association study of selenium concentrations.
Cornelis MC, Fornage M, Foy M, Xun P, Gladyshev VN, Morris S, Chasman DI, Hu FB, Rimm EB, Kraft P, Jordan JM, Mozaffarian D, He K
Human molecular genetics24(5)1469-77(2015 Mar)

Knockdown of IRX2 inhibits osteosarcoma cell proliferation and invasion by the AKT/MMP9 signaling pathway.
Liu T, Zhou W, Zhang F, Shi G, Teng H, Xiao J, Wang Y
Molecular medicine reports10(1)169-74(2014 Jul)

DNA-binding specificities of human transcription factors.
Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J
Cell152(1-2)327-39(2013 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

IRX2 transcription factor might represent a novel metastasis associated protein that acts as a negative regulator of cellular motility and as a repressor of chemokine expression and loss of IRX2 expression could therefore contribute to early hematogenous dissemination of breast cancer by sustaining chemokine secretion and enabling mobilization of tumor cells.
Title: Iroquois homeobox 2 suppresses cellular motility and chemokine expression in breast cancer cells.

IRX2 modulates the expression levels of MMP2 and VEGF in an AKTdependent manner.
Title: IRX2-mediated upregulation of MMP-9 and VEGF in a PI3K/AKT-dependent manner.

The mechanism by which IRX2 promoted cell proliferation and invasion by activating AKT and MMP9 was detected.
Title: Knockdown of IRX2 inhibits osteosarcoma cell proliferation and invasion by the AKT/MMP9 signaling pathway.

Results revealed 3 genes highly predictive of event-free survival (EFS), beyond age and MLL status: FLT3, IRX2, and TACC2.
Title: Gene expression profiles predictive of outcome and age in infant acute lymphoblastic leukemia: a Children's Oncology Group study.

Observational study of gene-disease association. (HuGE Navigator)
Title: A genome-wide scan maps a novel high myopia locus to 5p15.

The following IRX2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IRX2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu105635	XM_024454379.1 Latest version!	Homo sapiens iroquois homeobox 2 (IRX2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu30549	NM_001134222.2 Latest version!	Homo sapiens iroquois homeobox 2 (IRX2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu30549	NM_033267.5 Latest version!	Homo sapiens iroquois homeobox 2 (IRX2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu30549	XM_011513978.1 Latest version!	Homo sapiens iroquois homeobox 2 (IRX2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu30549	XM_011513979.2 Latest version!	Homo sapiens iroquois homeobox 2 (IRX2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
View Old Accession Versions >>
OHu30549	NM_001134222.1	Homo sapiens iroquois homeobox 2 (IRX2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu30549	XM_011513979.1	Homo sapiens iroquois homeobox 2 (IRX2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu30549	NM_033267.4	Homo sapiens iroquois homeobox 2 (IRX2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IRX2 ( XM_024454379.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024310147.1 Homo sapiens iroquois homeobox 2 (IRX2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu105635
Clone ID Related Accession (Same CDS sequence)	XM_024454379.1
Accession Version	XM_024454379.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1137bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	iroquois-class homeodomain protein IRX-2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCGGCG CCATCAGCTA CCACCCGTAC GGCAGCGCGG CCTACCCGTA CCAGCTCAAC 
GACCCCGCGT ACCGCAAGAA CGCCACGCGG GACGCCACGG CCACTCTCAA GGCCTGGCTC 
AACGAGCACC GCAAGAACCC CTACCCCACC AAGGGCGAGA AGATCATGCT AGCCATCATC 
ACCAAGATGA CCCTCACCCA GGTCTCCACC TGGTTCGCCA ACGCGCGCCG GCGCCTCAAG 
AAGGAGAACA AGATGACCTG GGCCCCGAGA AACAAAAGCG AAGATGAGGA CGAGGACGAG 
GGCGACGCTA CCAGAAGCAA GGACGAGAGT CCCGACAAGG CGCAGGAGGG CACGGAGACC 
TCGGCAGAGG ACGAAGGGAT CAGCCTGCAC GTGGACTCGC TCACGGATCA CTCGTGCTCG 
GCCGAGTCGG ACGGGGAGAA GCTTCCGTGC CGCGCCGGGG ACCCCCTGTG CGAATCGGGC 
TCGGAGTGCA AGGACAAGTA TGACGACCTG GAGGACGACG AGGACGACGA CGAGGAGGGC 
GAGCGGGGCC TGGCGCCGCC CAAGCCCGTG ACCTCGTCGC CGCTTACCGG CTTGGAGGCG 
CCGCTGCTGA GCCCCCCGCC CGAGGCCGCG CCCCGCGGTG GCCGCAAGAC GCCCCAGGGC 
AGCCGGACGT CTCCGGGCGC GCCGCCCCCC GCCAGCAAGC CCAAGCTGTG GTCGCTGGCC 
GAGATCGCCA CGTCGGACCT CAAGCAGCCG AGCCTGGGCC CGGGCTGCGG GCCACCGGGG 
CTGCCCGCGG CCGCCGCGCC GGCCTCAACC GGGGCACCGC CAGGAGGCTC GCCCTACCCT 
GCCTCGCCGC TGCTGGGCCG CCCCCTCTAC TACACGTCGC CCTTCTACGG CAACTACACA 
AACTACGGGA ACTTGAACGC GGCGCTGCAG GGCCAGGGTC TCCTGCGGTA CAACTCTGCG 
GCCGCGGCCC CCGGCGAGGC CCTGCACACC GCGCCAAAGG CGGCCAGCGA CGCGGGCAAG 
GCGGGCGCGC ACCCGCTCGA GTCCCACTAC CGGTCCCCGG GCGGCGGCTA CGAGCCCAAG 
AAAGATGCCA GCGAGGGCTG CACCGTGGTT GGCGGGGGCG TCCAGCCCTA CCTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024310147.1
CDS	772..1908
Translation	MTGAISYHPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGDATRSKDESPDKAQEGTETSAEDEGISLHVDSLTDHSCSAESDGEKLPCRAGDPLCESGSECKDKYDDLEDDEDDDEEGERGLAPPKPVTSSPLTGLEAPLLSPPPEAAPRGGRKTPQGSRTSPGAPPPASKPKLWSLAEIATSDLKQPSLGPGCGPPGLPAAAAPASTGAPPGGSPYPASPLLGRPLYYTSPFYGNYTNYGNLNAALQGQGLLRYNSAAAAPGEALHTAPKAASDAGKAGAHPLESHYRSPGGGYEPKKDASEGCTVVGGGVQPYL

Target ORF information:

RefSeq Version	XM_024454379.1
Organism	Homo sapiens(human)
Definition	Homo sapiens iroquois homeobox 2 (IRX2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024454379.1

ORF Insert Sequence:

ATGACCGGCG CCATCAGCTA CCACCCGTAC GGCAGCGCGG CCTACCCGTA CCAGCTCAAC 
GACCCCGCGT ACCGCAAGAA CGCCACGCGG GACGCCACGG CCACTCTCAA GGCCTGGCTC 
AACGAGCACC GCAAGAACCC CTACCCCACC AAGGGCGAGA AGATCATGCT AGCCATCATC 
ACCAAGATGA CCCTCACCCA GGTCTCCACC TGGTTCGCCA ACGCGCGCCG GCGCCTCAAG 
AAGGAGAACA AGATGACCTG GGCCCCGAGA AACAAAAGCG AAGATGAGGA CGAGGACGAG 
GGCGACGCTA CCAGAAGCAA GGACGAGAGT CCCGACAAGG CGCAGGAGGG CACGGAGACC 
TCGGCAGAGG ACGAAGGGAT CAGCCTGCAC GTGGACTCGC TCACGGATCA CTCGTGCTCG 
GCCGAGTCGG ACGGGGAGAA GCTTCCGTGC CGCGCCGGGG ACCCCCTGTG CGAATCGGGC 
TCGGAGTGCA AGGACAAGTA TGACGACCTG GAGGACGACG AGGACGACGA CGAGGAGGGC 
GAGCGGGGCC TGGCGCCGCC CAAGCCCGTG ACCTCGTCGC CGCTTACCGG CTTGGAGGCG 
CCGCTGCTGA GCCCCCCGCC CGAGGCCGCG CCCCGCGGTG GCCGCAAGAC GCCCCAGGGC 
AGCCGGACGT CTCCGGGCGC GCCGCCCCCC GCCAGCAAGC CCAAGCTGTG GTCGCTGGCC 
GAGATCGCCA CGTCGGACCT CAAGCAGCCG AGCCTGGGCC CGGGCTGCGG GCCACCGGGG 
CTGCCCGCGG CCGCCGCGCC GGCCTCAACC GGGGCACCGC CAGGAGGCTC GCCCTACCCT 
GCCTCGCCGC TGCTGGGCCG CCCCCTCTAC TACACGTCGC CCTTCTACGG CAACTACACA 
AACTACGGGA ACTTGAACGC GGCGCTGCAG GGCCAGGGTC TCCTGCGGTA CAACTCTGCG 
GCCGCGGCCC CCGGCGAGGC CCTGCACACC GCGCCAAAGG CGGCCAGCGA CGCGGGCAAG 
GCGGGCGCGC ACCCGCTCGA GTCCCACTAC CGGTCCCCGG GCGGCGGCTA CGAGCCCAAG 
AAAGATGCCA GCGAGGGCTG CACCGTGGTT GGCGGGGGCG TCCAGCCCTA CCTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRX2 ( NM_001134222.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001127694.1 Homo sapiens iroquois homeobox 2 (IRX2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30549
Clone ID Related Accession (Same CDS sequence)	XM_011513978.1 , NM_001134222.2 , XM_011513979.2 , NM_001134222.1 , NM_033267.4 , XM_011513979.1 , NM_033267.5
Accession Version	NM_001134222.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1416bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	iroquois-class homeodomain protein IRX-2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC091891.3, BC065189.1, AY335940.1 and BM969863.1. On May 31, 2019 this sequence version replaced NM_001134222.1. Transcript Variant: This variant (2) differs in the 3' UTR, compared to variant 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY335940.1, BC065189.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCTACC CGCAGGGCTA CCTGTACCAG GCGCCCGGCT CGCTGGCGCT CTACTCGTGC 
CCGGCCTACG GCGCGTCGGC TTTGGCGGCT CCGCGCAGCG AGGAGCTGGC GCGCTCGGCG 
TCGGGCTCGG CGTTCAGCCC CTACCCGGGC TCGGCGGCCT TCACGGCGCA GGCGGCCACC 
GGCTTCGGGA GCCCGCTGCA GTACTCGGCC GACGCCGCCG CCGCCGCCGC CGGCTTCCCG 
TCCTACATGG GCGCACCCTA CGACGCGCAC ACCACCGGCA TGACCGGCGC CATCAGCTAC 
CACCCGTACG GCAGCGCGGC CTACCCGTAC CAGCTCAACG ACCCCGCGTA CCGCAAGAAC 
GCCACGCGGG ACGCCACGGC CACTCTCAAG GCCTGGCTCA ACGAGCACCG CAAGAACCCC 
TACCCCACCA AGGGCGAGAA GATCATGCTA GCCATCATCA CCAAGATGAC CCTCACCCAG 
GTCTCCACCT GGTTCGCCAA CGCGCGCCGG CGCCTCAAGA AGGAGAACAA GATGACCTGG 
GCCCCGAGAA ACAAAAGCGA AGATGAGGAC GAGGACGAGG GCGACGCTAC CAGAAGCAAG 
GACGAGAGTC CCGACAAGGC GCAGGAGGGC ACGGAGACCT CGGCAGAGGA CGAAGGGATC 
AGCCTGCACG TGGACTCGCT CACGGATCAC TCGTGCTCGG CCGAGTCGGA CGGGGAGAAG 
CTTCCGTGCC GCGCCGGGGA CCCCCTGTGC GAATCGGGCT CGGAGTGCAA GGACAAGTAT 
GACGACCTGG AGGACGACGA GGACGACGAC GAGGAGGGCG AGCGGGGCCT GGCGCCGCCC 
AAGCCCGTGA CCTCGTCGCC GCTTACCGGC TTGGAGGCGC CGCTGCTGAG CCCCCCGCCC 
GAGGCCGCGC CCCGCGGTGG CCGCAAGACG CCCCAGGGCA GCCGGACGTC TCCGGGCGCG 
CCGCCCCCCG CCAGCAAGCC CAAGCTGTGG TCGCTGGCCG AGATCGCCAC GTCGGACCTC 
AAGCAGCCGA GCCTGGGCCC GGGCTGCGGG CCACCGGGGC TGCCCGCGGC CGCCGCGCCG 
GCCTCAACCG GGGCACCGCC AGGAGGCTCG CCCTACCCTG CCTCGCCGCT GCTGGGCCGC 
CCCCTCTACT ACACGTCGCC CTTCTACGGC AACTACACAA ACTACGGGAA CTTGAACGCG 
GCGCTGCAGG GCCAGGGTCT CCTGCGGTAC AACTCTGCGG CCGCGGCCCC CGGCGAGGCC 
CTGCACACCG CGCCAAAGGC GGCCAGCGAC GCGGGCAAGG CGGGCGCGCA CCCGCTCGAG 
TCCCACTACC GGTCCCCGGG CGGCGGCTAC GAGCCCAAGA AAGATGCCAG CGAGGGCTGC 
ACCGTGGTTG GCGGGGGCGT CCAGCCCTAC CTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001127694.1
CDS	265..1680
Translation	MSYPQGYLYQAPGSLALYSCPAYGASALAAPRSEELARSASGSAFSPYPGSAAFTAQAATGFGSPLQYSADAAAAAAGFPSYMGAPYDAHTTGMTGAISYHPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGDATRSKDESPDKAQEGTETSAEDEGISLHVDSLTDHSCSAESDGEKLPCRAGDPLCESGSECKDKYDDLEDDEDDDEEGERGLAPPKPVTSSPLTGLEAPLLSPPPEAAPRGGRKTPQGSRTSPGAPPPASKPKLWSLAEIATSDLKQPSLGPGCGPPGLPAAAAPASTGAPPGGSPYPASPLLGRPLYYTSPFYGNYTNYGNLNAALQGQGLLRYNSAAAAPGEALHTAPKAASDAGKAGAHPLESHYRSPGGGYEPKKDASEGCTVVGGGVQPYL

Target ORF information:

RefSeq Version	NM_001134222.2
Organism	Homo sapiens(human)
Definition	Homo sapiens iroquois homeobox 2 (IRX2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001134222.2

ORF Insert Sequence:

ATGTCCTACC CGCAGGGCTA CCTGTACCAG GCGCCCGGCT CGCTGGCGCT CTACTCGTGC 
CCGGCCTACG GCGCGTCGGC TTTGGCGGCT CCGCGCAGCG AGGAGCTGGC GCGCTCGGCG 
TCGGGCTCGG CGTTCAGCCC CTACCCGGGC TCGGCGGCCT TCACGGCGCA GGCGGCCACC 
GGCTTCGGGA GCCCGCTGCA GTACTCGGCC GACGCCGCCG CCGCCGCCGC CGGCTTCCCG 
TCCTACATGG GCGCACCCTA CGACGCGCAC ACCACCGGCA TGACCGGCGC CATCAGCTAC 
CACCCGTACG GCAGCGCGGC CTACCCGTAC CAGCTCAACG ACCCCGCGTA CCGCAAGAAC 
GCCACGCGGG ACGCCACGGC CACTCTCAAG GCCTGGCTCA ACGAGCACCG CAAGAACCCC 
TACCCCACCA AGGGCGAGAA GATCATGCTA GCCATCATCA CCAAGATGAC CCTCACCCAG 
GTCTCCACCT GGTTCGCCAA CGCGCGCCGG CGCCTCAAGA AGGAGAACAA GATGACCTGG 
GCCCCGAGAA ACAAAAGCGA AGATGAGGAC GAGGACGAGG GCGACGCTAC CAGAAGCAAG 
GACGAGAGTC CCGACAAGGC GCAGGAGGGC ACGGAGACCT CGGCAGAGGA CGAAGGGATC 
AGCCTGCACG TGGACTCGCT CACGGATCAC TCGTGCTCGG CCGAGTCGGA CGGGGAGAAG 
CTTCCGTGCC GCGCCGGGGA CCCCCTGTGC GAATCGGGCT CGGAGTGCAA GGACAAGTAT 
GACGACCTGG AGGACGACGA GGACGACGAC GAGGAGGGCG AGCGGGGCCT GGCGCCGCCC 
AAGCCCGTGA CCTCGTCGCC GCTTACCGGC TTGGAGGCGC CGCTGCTGAG CCCCCCGCCC 
GAGGCCGCGC CCCGCGGTGG CCGCAAGACG CCCCAGGGCA GCCGGACGTC TCCGGGCGCG 
CCGCCCCCCG CCAGCAAGCC CAAGCTGTGG TCGCTGGCCG AGATCGCCAC GTCGGACCTC 
AAGCAGCCGA GCCTGGGCCC GGGCTGCGGG CCACCGGGGC TGCCCGCGGC CGCCGCGCCG 
GCCTCAACCG GGGCACCGCC AGGAGGCTCG CCCTACCCTG CCTCGCCGCT GCTGGGCCGC 
CCCCTCTACT ACACGTCGCC CTTCTACGGC AACTACACAA ACTACGGGAA CTTGAACGCG 
GCGCTGCAGG GCCAGGGTCT CCTGCGGTAC AACTCTGCGG CCGCGGCCCC CGGCGAGGCC 
CTGCACACCG CGCCAAAGGC GGCCAGCGAC GCGGGCAAGG CGGGCGCGCA CCCGCTCGAG 
TCCCACTACC GGTCCCCGGG CGGCGGCTAC GAGCCCAAGA AAGATGCCAG CGAGGGCTGC 
ACCGTGGTTG GCGGGGGCGT CCAGCCCTAC CTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRX2 ( NM_001134222.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001127694.1 Homo sapiens iroquois homeobox 2 (IRX2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30549
Clone ID Related Accession (Same CDS sequence)	XM_011513978.1 , NM_001134222.2 , XM_011513979.2 , NM_001134222.1 , NM_033267.4 , XM_011513979.1 , NM_033267.5
Accession Version	NM_001134222.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1416bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-17
Organism	Homo sapiens(human)
Product	iroquois-class homeodomain protein IRX-2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC065189.1, AY335940.1 and BM969863.1. Transcript Variant: This variant (2) differs in the 3' UTR, compared to variant 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY335940.1, BC065189.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCTACC CGCAGGGCTA CCTGTACCAG GCGCCCGGCT CGCTGGCGCT CTACTCGTGC 
CCGGCCTACG GCGCGTCGGC TTTGGCGGCT CCGCGCAGCG AGGAGCTGGC GCGCTCGGCG 
TCGGGCTCGG CGTTCAGCCC CTACCCGGGC TCGGCGGCCT TCACGGCGCA GGCGGCCACC 
GGCTTCGGGA GCCCGCTGCA GTACTCGGCC GACGCCGCCG CCGCCGCCGC CGGCTTCCCG 
TCCTACATGG GCGCACCCTA CGACGCGCAC ACCACCGGCA TGACCGGCGC CATCAGCTAC 
CACCCGTACG GCAGCGCGGC CTACCCGTAC CAGCTCAACG ACCCCGCGTA CCGCAAGAAC 
GCCACGCGGG ACGCCACGGC CACTCTCAAG GCCTGGCTCA ACGAGCACCG CAAGAACCCC 
TACCCCACCA AGGGCGAGAA GATCATGCTA GCCATCATCA CCAAGATGAC CCTCACCCAG 
GTCTCCACCT GGTTCGCCAA CGCGCGCCGG CGCCTCAAGA AGGAGAACAA GATGACCTGG 
GCCCCGAGAA ACAAAAGCGA AGATGAGGAC GAGGACGAGG GCGACGCTAC CAGAAGCAAG 
GACGAGAGTC CCGACAAGGC GCAGGAGGGC ACGGAGACCT CGGCAGAGGA CGAAGGGATC 
AGCCTGCACG TGGACTCGCT CACGGATCAC TCGTGCTCGG CCGAGTCGGA CGGGGAGAAG 
CTTCCGTGCC GCGCCGGGGA CCCCCTGTGC GAATCGGGCT CGGAGTGCAA GGACAAGTAT 
GACGACCTGG AGGACGACGA GGACGACGAC GAGGAGGGCG AGCGGGGCCT GGCGCCGCCC 
AAGCCCGTGA CCTCGTCGCC GCTTACCGGC TTGGAGGCGC CGCTGCTGAG CCCCCCGCCC 
GAGGCCGCGC CCCGCGGTGG CCGCAAGACG CCCCAGGGCA GCCGGACGTC TCCGGGCGCG 
CCGCCCCCCG CCAGCAAGCC CAAGCTGTGG TCGCTGGCCG AGATCGCCAC GTCGGACCTC 
AAGCAGCCGA GCCTGGGCCC GGGCTGCGGG CCACCGGGGC TGCCCGCGGC CGCCGCGCCG 
GCCTCAACCG GGGCACCGCC AGGAGGCTCG CCCTACCCTG CCTCGCCGCT GCTGGGCCGC 
CCCCTCTACT ACACGTCGCC CTTCTACGGC AACTACACAA ACTACGGGAA CTTGAACGCG 
GCGCTGCAGG GCCAGGGTCT CCTGCGGTAC AACTCTGCGG CCGCGGCCCC CGGCGAGGCC 
CTGCACACCG CGCCAAAGGC GGCCAGCGAC GCGGGCAAGG CGGGCGCGCA CCCGCTCGAG 
TCCCACTACC GGTCCCCGGG CGGCGGCTAC GAGCCCAAGA AAGATGCCAG CGAGGGCTGC 
ACCGTGGTTG GCGGGGGCGT CCAGCCCTAC CTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001127694.1
CDS	243..1658
Translation	MSYPQGYLYQAPGSLALYSCPAYGASALAAPRSEELARSASGSAFSPYPGSAAFTAQAATGFGSPLQYSADAAAAAAGFPSYMGAPYDAHTTGMTGAISYHPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGDATRSKDESPDKAQEGTETSAEDEGISLHVDSLTDHSCSAESDGEKLPCRAGDPLCESGSECKDKYDDLEDDEDDDEEGERGLAPPKPVTSSPLTGLEAPLLSPPPEAAPRGGRKTPQGSRTSPGAPPPASKPKLWSLAEIATSDLKQPSLGPGCGPPGLPAAAAPASTGAPPGGSPYPASPLLGRPLYYTSPFYGNYTNYGNLNAALQGQGLLRYNSAAAAPGEALHTAPKAASDAGKAGAHPLESHYRSPGGGYEPKKDASEGCTVVGGGVQPYL

Target ORF information:

RefSeq Version	NM_001134222.1
Organism	Homo sapiens(human)
Definition	Homo sapiens iroquois homeobox 2 (IRX2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001134222.1

ORF Insert Sequence:

ATGTCCTACC CGCAGGGCTA CCTGTACCAG GCGCCCGGCT CGCTGGCGCT CTACTCGTGC 
CCGGCCTACG GCGCGTCGGC TTTGGCGGCT CCGCGCAGCG AGGAGCTGGC GCGCTCGGCG 
TCGGGCTCGG CGTTCAGCCC CTACCCGGGC TCGGCGGCCT TCACGGCGCA GGCGGCCACC 
GGCTTCGGGA GCCCGCTGCA GTACTCGGCC GACGCCGCCG CCGCCGCCGC CGGCTTCCCG 
TCCTACATGG GCGCACCCTA CGACGCGCAC ACCACCGGCA TGACCGGCGC CATCAGCTAC 
CACCCGTACG GCAGCGCGGC CTACCCGTAC CAGCTCAACG ACCCCGCGTA CCGCAAGAAC 
GCCACGCGGG ACGCCACGGC CACTCTCAAG GCCTGGCTCA ACGAGCACCG CAAGAACCCC 
TACCCCACCA AGGGCGAGAA GATCATGCTA GCCATCATCA CCAAGATGAC CCTCACCCAG 
GTCTCCACCT GGTTCGCCAA CGCGCGCCGG CGCCTCAAGA AGGAGAACAA GATGACCTGG 
GCCCCGAGAA ACAAAAGCGA AGATGAGGAC GAGGACGAGG GCGACGCTAC CAGAAGCAAG 
GACGAGAGTC CCGACAAGGC GCAGGAGGGC ACGGAGACCT CGGCAGAGGA CGAAGGGATC 
AGCCTGCACG TGGACTCGCT CACGGATCAC TCGTGCTCGG CCGAGTCGGA CGGGGAGAAG 
CTTCCGTGCC GCGCCGGGGA CCCCCTGTGC GAATCGGGCT CGGAGTGCAA GGACAAGTAT 
GACGACCTGG AGGACGACGA GGACGACGAC GAGGAGGGCG AGCGGGGCCT GGCGCCGCCC 
AAGCCCGTGA CCTCGTCGCC GCTTACCGGC TTGGAGGCGC CGCTGCTGAG CCCCCCGCCC 
GAGGCCGCGC CCCGCGGTGG CCGCAAGACG CCCCAGGGCA GCCGGACGTC TCCGGGCGCG 
CCGCCCCCCG CCAGCAAGCC CAAGCTGTGG TCGCTGGCCG AGATCGCCAC GTCGGACCTC 
AAGCAGCCGA GCCTGGGCCC GGGCTGCGGG CCACCGGGGC TGCCCGCGGC CGCCGCGCCG 
GCCTCAACCG GGGCACCGCC AGGAGGCTCG CCCTACCCTG CCTCGCCGCT GCTGGGCCGC 
CCCCTCTACT ACACGTCGCC CTTCTACGGC AACTACACAA ACTACGGGAA CTTGAACGCG 
GCGCTGCAGG GCCAGGGTCT CCTGCGGTAC AACTCTGCGG CCGCGGCCCC CGGCGAGGCC 
CTGCACACCG CGCCAAAGGC GGCCAGCGAC GCGGGCAAGG CGGGCGCGCA CCCGCTCGAG 
TCCCACTACC GGTCCCCGGG CGGCGGCTAC GAGCCCAAGA AAGATGCCAG CGAGGGCTGC 
ACCGTGGTTG GCGGGGGCGT CCAGCCCTAC CTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRX2 ( NM_033267.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_150366.1 Homo sapiens iroquois homeobox 2 (IRX2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30549
Clone ID Related Accession (Same CDS sequence)	XM_011513978.1 , NM_001134222.2 , XM_011513979.2 , NM_001134222.1 , NM_033267.4 , XM_011513979.1 , NM_033267.5
Accession Version	NM_033267.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1416bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-27
Organism	Homo sapiens(human)
Product	iroquois-class homeodomain protein IRX-2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC065189.1, AB188492.1, AI928035.1, AI131378.1, AY335940.1 and BM969863.1. On Aug 20, 2008 this sequence version replaced NM_033267.3. Transcript Variant: This variant (1) represents the longer transcript. ##Evidence-Data-START## Transcript exon combination :: AB188492.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCTACC CGCAGGGCTA CCTGTACCAG GCGCCCGGCT CGCTGGCGCT CTACTCGTGC 
CCGGCCTACG GCGCGTCGGC TTTGGCGGCT CCGCGCAGCG AGGAGCTGGC GCGCTCGGCG 
TCGGGCTCGG CGTTCAGCCC CTACCCGGGC TCGGCGGCCT TCACGGCGCA GGCGGCCACC 
GGCTTCGGGA GCCCGCTGCA GTACTCGGCC GACGCCGCCG CCGCCGCCGC CGGCTTCCCG 
TCCTACATGG GCGCACCCTA CGACGCGCAC ACCACCGGCA TGACCGGCGC CATCAGCTAC 
CACCCGTACG GCAGCGCGGC CTACCCGTAC CAGCTCAACG ACCCCGCGTA CCGCAAGAAC 
GCCACGCGGG ACGCCACGGC CACTCTCAAG GCCTGGCTCA ACGAGCACCG CAAGAACCCC 
TACCCCACCA AGGGCGAGAA GATCATGCTA GCCATCATCA CCAAGATGAC CCTCACCCAG 
GTCTCCACCT GGTTCGCCAA CGCGCGCCGG CGCCTCAAGA AGGAGAACAA GATGACCTGG 
GCCCCGAGAA ACAAAAGCGA AGATGAGGAC GAGGACGAGG GCGACGCTAC CAGAAGCAAG 
GACGAGAGTC CCGACAAGGC GCAGGAGGGC ACGGAGACCT CGGCAGAGGA CGAAGGGATC 
AGCCTGCACG TGGACTCGCT CACGGATCAC TCGTGCTCGG CCGAGTCGGA CGGGGAGAAG 
CTTCCGTGCC GCGCCGGGGA CCCCCTGTGC GAATCGGGCT CGGAGTGCAA GGACAAGTAT 
GACGACCTGG AGGACGACGA GGACGACGAC GAGGAGGGCG AGCGGGGCCT GGCGCCGCCC 
AAGCCCGTGA CCTCGTCGCC GCTTACCGGC TTGGAGGCGC CGCTGCTGAG CCCCCCGCCC 
GAGGCCGCGC CCCGCGGTGG CCGCAAGACG CCCCAGGGCA GCCGGACGTC TCCGGGCGCG 
CCGCCCCCCG CCAGCAAGCC CAAGCTGTGG TCGCTGGCCG AGATCGCCAC GTCGGACCTC 
AAGCAGCCGA GCCTGGGCCC GGGCTGCGGG CCACCGGGGC TGCCCGCGGC CGCCGCGCCG 
GCCTCAACCG GGGCACCGCC AGGAGGCTCG CCCTACCCTG CCTCGCCGCT GCTGGGCCGC 
CCCCTCTACT ACACGTCGCC CTTCTACGGC AACTACACAA ACTACGGGAA CTTGAACGCG 
GCGCTGCAGG GCCAGGGTCT CCTGCGGTAC AACTCTGCGG CCGCGGCCCC CGGCGAGGCC 
CTGCACACCG CGCCAAAGGC GGCCAGCGAC GCGGGCAAGG CGGGCGCGCA CCCGCTCGAG 
TCCCACTACC GGTCCCCGGG CGGCGGCTAC GAGCCCAAGA AAGATGCCAG CGAGGGCTGC 
ACCGTGGTTG GCGGGGGCGT CCAGCCCTAC CTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_150366.1
CDS	243..1658
Translation	MSYPQGYLYQAPGSLALYSCPAYGASALAAPRSEELARSASGSAFSPYPGSAAFTAQAATGFGSPLQYSADAAAAAAGFPSYMGAPYDAHTTGMTGAISYHPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGDATRSKDESPDKAQEGTETSAEDEGISLHVDSLTDHSCSAESDGEKLPCRAGDPLCESGSECKDKYDDLEDDEDDDEEGERGLAPPKPVTSSPLTGLEAPLLSPPPEAAPRGGRKTPQGSRTSPGAPPPASKPKLWSLAEIATSDLKQPSLGPGCGPPGLPAAAAPASTGAPPGGSPYPASPLLGRPLYYTSPFYGNYTNYGNLNAALQGQGLLRYNSAAAAPGEALHTAPKAASDAGKAGAHPLESHYRSPGGGYEPKKDASEGCTVVGGGVQPYL

Target ORF information:

RefSeq Version	NM_033267.4
Organism	Homo sapiens(human)
Definition	Homo sapiens iroquois homeobox 2 (IRX2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033267.4

ORF Insert Sequence:

ATGTCCTACC CGCAGGGCTA CCTGTACCAG GCGCCCGGCT CGCTGGCGCT CTACTCGTGC 
CCGGCCTACG GCGCGTCGGC TTTGGCGGCT CCGCGCAGCG AGGAGCTGGC GCGCTCGGCG 
TCGGGCTCGG CGTTCAGCCC CTACCCGGGC TCGGCGGCCT TCACGGCGCA GGCGGCCACC 
GGCTTCGGGA GCCCGCTGCA GTACTCGGCC GACGCCGCCG CCGCCGCCGC CGGCTTCCCG 
TCCTACATGG GCGCACCCTA CGACGCGCAC ACCACCGGCA TGACCGGCGC CATCAGCTAC 
CACCCGTACG GCAGCGCGGC CTACCCGTAC CAGCTCAACG ACCCCGCGTA CCGCAAGAAC 
GCCACGCGGG ACGCCACGGC CACTCTCAAG GCCTGGCTCA ACGAGCACCG CAAGAACCCC 
TACCCCACCA AGGGCGAGAA GATCATGCTA GCCATCATCA CCAAGATGAC CCTCACCCAG 
GTCTCCACCT GGTTCGCCAA CGCGCGCCGG CGCCTCAAGA AGGAGAACAA GATGACCTGG 
GCCCCGAGAA ACAAAAGCGA AGATGAGGAC GAGGACGAGG GCGACGCTAC CAGAAGCAAG 
GACGAGAGTC CCGACAAGGC GCAGGAGGGC ACGGAGACCT CGGCAGAGGA CGAAGGGATC 
AGCCTGCACG TGGACTCGCT CACGGATCAC TCGTGCTCGG CCGAGTCGGA CGGGGAGAAG 
CTTCCGTGCC GCGCCGGGGA CCCCCTGTGC GAATCGGGCT CGGAGTGCAA GGACAAGTAT 
GACGACCTGG AGGACGACGA GGACGACGAC GAGGAGGGCG AGCGGGGCCT GGCGCCGCCC 
AAGCCCGTGA CCTCGTCGCC GCTTACCGGC TTGGAGGCGC CGCTGCTGAG CCCCCCGCCC 
GAGGCCGCGC CCCGCGGTGG CCGCAAGACG CCCCAGGGCA GCCGGACGTC TCCGGGCGCG 
CCGCCCCCCG CCAGCAAGCC CAAGCTGTGG TCGCTGGCCG AGATCGCCAC GTCGGACCTC 
AAGCAGCCGA GCCTGGGCCC GGGCTGCGGG CCACCGGGGC TGCCCGCGGC CGCCGCGCCG 
GCCTCAACCG GGGCACCGCC AGGAGGCTCG CCCTACCCTG CCTCGCCGCT GCTGGGCCGC 
CCCCTCTACT ACACGTCGCC CTTCTACGGC AACTACACAA ACTACGGGAA CTTGAACGCG 
GCGCTGCAGG GCCAGGGTCT CCTGCGGTAC AACTCTGCGG CCGCGGCCCC CGGCGAGGCC 
CTGCACACCG CGCCAAAGGC GGCCAGCGAC GCGGGCAAGG CGGGCGCGCA CCCGCTCGAG 
TCCCACTACC GGTCCCCGGG CGGCGGCTAC GAGCCCAAGA AAGATGCCAG CGAGGGCTGC 
ACCGTGGTTG GCGGGGGCGT CCAGCCCTAC CTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRX2 ( NM_033267.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_150366.1 Homo sapiens iroquois homeobox 2 (IRX2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30549
Clone ID Related Accession (Same CDS sequence)	XM_011513978.1 , NM_001134222.2 , XM_011513979.2 , NM_001134222.1 , NM_033267.4 , XM_011513979.1 , NM_033267.5
Accession Version	NM_033267.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1416bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	iroquois-class homeodomain protein IRX-2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC091891.3, BC065189.1, AB188492.1, AI928035.1, AI131378.1, AY335940.1 and BM969863.1. On Nov 22, 2018 this sequence version replaced NM_033267.4. Transcript Variant: This variant (1) represents the longer transcript. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB188492.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000302057.6/ ENSP00000307006.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCCTACC CGCAGGGCTA CCTGTACCAG GCGCCCGGCT CGCTGGCGCT CTACTCGTGC 
CCGGCCTACG GCGCGTCGGC TTTGGCGGCT CCGCGCAGCG AGGAGCTGGC GCGCTCGGCG 
TCGGGCTCGG CGTTCAGCCC CTACCCGGGC TCGGCGGCCT TCACGGCGCA GGCGGCCACC 
GGCTTCGGGA GCCCGCTGCA GTACTCGGCC GACGCCGCCG CCGCCGCCGC CGGCTTCCCG 
TCCTACATGG GCGCACCCTA CGACGCGCAC ACCACCGGCA TGACCGGCGC CATCAGCTAC 
CACCCGTACG GCAGCGCGGC CTACCCGTAC CAGCTCAACG ACCCCGCGTA CCGCAAGAAC 
GCCACGCGGG ACGCCACGGC CACTCTCAAG GCCTGGCTCA ACGAGCACCG CAAGAACCCC 
TACCCCACCA AGGGCGAGAA GATCATGCTA GCCATCATCA CCAAGATGAC CCTCACCCAG 
GTCTCCACCT GGTTCGCCAA CGCGCGCCGG CGCCTCAAGA AGGAGAACAA GATGACCTGG 
GCCCCGAGAA ACAAAAGCGA AGATGAGGAC GAGGACGAGG GCGACGCTAC CAGAAGCAAG 
GACGAGAGTC CCGACAAGGC GCAGGAGGGC ACGGAGACCT CGGCAGAGGA CGAAGGGATC 
AGCCTGCACG TGGACTCGCT CACGGATCAC TCGTGCTCGG CCGAGTCGGA CGGGGAGAAG 
CTTCCGTGCC GCGCCGGGGA CCCCCTGTGC GAATCGGGCT CGGAGTGCAA GGACAAGTAT 
GACGACCTGG AGGACGACGA GGACGACGAC GAGGAGGGCG AGCGGGGCCT GGCGCCGCCC 
AAGCCCGTGA CCTCGTCGCC GCTTACCGGC TTGGAGGCGC CGCTGCTGAG CCCCCCGCCC 
GAGGCCGCGC CCCGCGGTGG CCGCAAGACG CCCCAGGGCA GCCGGACGTC TCCGGGCGCG 
CCGCCCCCCG CCAGCAAGCC CAAGCTGTGG TCGCTGGCCG AGATCGCCAC GTCGGACCTC 
AAGCAGCCGA GCCTGGGCCC GGGCTGCGGG CCACCGGGGC TGCCCGCGGC CGCCGCGCCG 
GCCTCAACCG GGGCACCGCC AGGAGGCTCG CCCTACCCTG CCTCGCCGCT GCTGGGCCGC 
CCCCTCTACT ACACGTCGCC CTTCTACGGC AACTACACAA ACTACGGGAA CTTGAACGCG 
GCGCTGCAGG GCCAGGGTCT CCTGCGGTAC AACTCTGCGG CCGCGGCCCC CGGCGAGGCC 
CTGCACACCG CGCCAAAGGC GGCCAGCGAC GCGGGCAAGG CGGGCGCGCA CCCGCTCGAG 
TCCCACTACC GGTCCCCGGG CGGCGGCTAC GAGCCCAAGA AAGATGCCAG CGAGGGCTGC 
ACCGTGGTTG GCGGGGGCGT CCAGCCCTAC CTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_150366.1
CDS	265..1680
Translation	MSYPQGYLYQAPGSLALYSCPAYGASALAAPRSEELARSASGSAFSPYPGSAAFTAQAATGFGSPLQYSADAAAAAAGFPSYMGAPYDAHTTGMTGAISYHPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGDATRSKDESPDKAQEGTETSAEDEGISLHVDSLTDHSCSAESDGEKLPCRAGDPLCESGSECKDKYDDLEDDEDDDEEGERGLAPPKPVTSSPLTGLEAPLLSPPPEAAPRGGRKTPQGSRTSPGAPPPASKPKLWSLAEIATSDLKQPSLGPGCGPPGLPAAAAPASTGAPPGGSPYPASPLLGRPLYYTSPFYGNYTNYGNLNAALQGQGLLRYNSAAAAPGEALHTAPKAASDAGKAGAHPLESHYRSPGGGYEPKKDASEGCTVVGGGVQPYL

Target ORF information:

RefSeq Version	NM_033267.5
Organism	Homo sapiens(human)
Definition	Homo sapiens iroquois homeobox 2 (IRX2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033267.5

ORF Insert Sequence:

ATGTCCTACC CGCAGGGCTA CCTGTACCAG GCGCCCGGCT CGCTGGCGCT CTACTCGTGC 
CCGGCCTACG GCGCGTCGGC TTTGGCGGCT CCGCGCAGCG AGGAGCTGGC GCGCTCGGCG 
TCGGGCTCGG CGTTCAGCCC CTACCCGGGC TCGGCGGCCT TCACGGCGCA GGCGGCCACC 
GGCTTCGGGA GCCCGCTGCA GTACTCGGCC GACGCCGCCG CCGCCGCCGC CGGCTTCCCG 
TCCTACATGG GCGCACCCTA CGACGCGCAC ACCACCGGCA TGACCGGCGC CATCAGCTAC 
CACCCGTACG GCAGCGCGGC CTACCCGTAC CAGCTCAACG ACCCCGCGTA CCGCAAGAAC 
GCCACGCGGG ACGCCACGGC CACTCTCAAG GCCTGGCTCA ACGAGCACCG CAAGAACCCC 
TACCCCACCA AGGGCGAGAA GATCATGCTA GCCATCATCA CCAAGATGAC CCTCACCCAG 
GTCTCCACCT GGTTCGCCAA CGCGCGCCGG CGCCTCAAGA AGGAGAACAA GATGACCTGG 
GCCCCGAGAA ACAAAAGCGA AGATGAGGAC GAGGACGAGG GCGACGCTAC CAGAAGCAAG 
GACGAGAGTC CCGACAAGGC GCAGGAGGGC ACGGAGACCT CGGCAGAGGA CGAAGGGATC 
AGCCTGCACG TGGACTCGCT CACGGATCAC TCGTGCTCGG CCGAGTCGGA CGGGGAGAAG 
CTTCCGTGCC GCGCCGGGGA CCCCCTGTGC GAATCGGGCT CGGAGTGCAA GGACAAGTAT 
GACGACCTGG AGGACGACGA GGACGACGAC GAGGAGGGCG AGCGGGGCCT GGCGCCGCCC 
AAGCCCGTGA CCTCGTCGCC GCTTACCGGC TTGGAGGCGC CGCTGCTGAG CCCCCCGCCC 
GAGGCCGCGC CCCGCGGTGG CCGCAAGACG CCCCAGGGCA GCCGGACGTC TCCGGGCGCG 
CCGCCCCCCG CCAGCAAGCC CAAGCTGTGG TCGCTGGCCG AGATCGCCAC GTCGGACCTC 
AAGCAGCCGA GCCTGGGCCC GGGCTGCGGG CCACCGGGGC TGCCCGCGGC CGCCGCGCCG 
GCCTCAACCG GGGCACCGCC AGGAGGCTCG CCCTACCCTG CCTCGCCGCT GCTGGGCCGC 
CCCCTCTACT ACACGTCGCC CTTCTACGGC AACTACACAA ACTACGGGAA CTTGAACGCG 
GCGCTGCAGG GCCAGGGTCT CCTGCGGTAC AACTCTGCGG CCGCGGCCCC CGGCGAGGCC 
CTGCACACCG CGCCAAAGGC GGCCAGCGAC GCGGGCAAGG CGGGCGCGCA CCCGCTCGAG 
TCCCACTACC GGTCCCCGGG CGGCGGCTAC GAGCCCAAGA AAGATGCCAG CGAGGGCTGC 
ACCGTGGTTG GCGGGGGCGT CCAGCCCTAC CTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRX2 ( XM_011513978.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512280.1 Homo sapiens iroquois homeobox 2 (IRX2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu30549
Clone ID Related Accession (Same CDS sequence)	XM_011513978.1 , NM_001134222.2 , XM_011513979.2 , NM_001134222.1 , NM_033267.4 , XM_011513979.1 , NM_033267.5
Accession Version	XM_011513978.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1416bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	iroquois-class homeodomain protein IRX-2 isoform X1
Comment

ATGTCCTACC CGCAGGGCTA CCTGTACCAG GCGCCCGGCT CGCTGGCGCT CTACTCGTGC 
CCGGCCTACG GCGCGTCGGC TTTGGCGGCT CCGCGCAGCG AGGAGCTGGC GCGCTCGGCG 
TCGGGCTCGG CGTTCAGCCC CTACCCGGGC TCGGCGGCCT TCACGGCGCA GGCGGCCACC 
GGCTTCGGGA GCCCGCTGCA GTACTCGGCC GACGCCGCCG CCGCCGCCGC CGGCTTCCCG 
TCCTACATGG GCGCACCCTA CGACGCGCAC ACCACCGGCA TGACCGGCGC CATCAGCTAC 
CACCCGTACG GCAGCGCGGC CTACCCGTAC CAGCTCAACG ACCCCGCGTA CCGCAAGAAC 
GCCACGCGGG ACGCCACGGC CACTCTCAAG GCCTGGCTCA ACGAGCACCG CAAGAACCCC 
TACCCCACCA AGGGCGAGAA GATCATGCTA GCCATCATCA CCAAGATGAC CCTCACCCAG 
GTCTCCACCT GGTTCGCCAA CGCGCGCCGG CGCCTCAAGA AGGAGAACAA GATGACCTGG 
GCCCCGAGAA ACAAAAGCGA AGATGAGGAC GAGGACGAGG GCGACGCTAC CAGAAGCAAG 
GACGAGAGTC CCGACAAGGC GCAGGAGGGC ACGGAGACCT CGGCAGAGGA CGAAGGGATC 
AGCCTGCACG TGGACTCGCT CACGGATCAC TCGTGCTCGG CCGAGTCGGA CGGGGAGAAG 
CTTCCGTGCC GCGCCGGGGA CCCCCTGTGC GAATCGGGCT CGGAGTGCAA GGACAAGTAT 
GACGACCTGG AGGACGACGA GGACGACGAC GAGGAGGGCG AGCGGGGCCT GGCGCCGCCC 
AAGCCCGTGA CCTCGTCGCC GCTTACCGGC TTGGAGGCGC CGCTGCTGAG CCCCCCGCCC 
GAGGCCGCGC CCCGCGGTGG CCGCAAGACG CCCCAGGGCA GCCGGACGTC TCCGGGCGCG 
CCGCCCCCCG CCAGCAAGCC CAAGCTGTGG TCGCTGGCCG AGATCGCCAC GTCGGACCTC 
AAGCAGCCGA GCCTGGGCCC GGGCTGCGGG CCACCGGGGC TGCCCGCGGC CGCCGCGCCG 
GCCTCAACCG GGGCACCGCC AGGAGGCTCG CCCTACCCTG CCTCGCCGCT GCTGGGCCGC 
CCCCTCTACT ACACGTCGCC CTTCTACGGC AACTACACAA ACTACGGGAA CTTGAACGCG 
GCGCTGCAGG GCCAGGGTCT CCTGCGGTAC AACTCTGCGG CCGCGGCCCC CGGCGAGGCC 
CTGCACACCG CGCCAAAGGC GGCCAGCGAC GCGGGCAAGG CGGGCGCGCA CCCGCTCGAG 
TCCCACTACC GGTCCCCGGG CGGCGGCTAC GAGCCCAAGA AAGATGCCAG CGAGGGCTGC 
ACCGTGGTTG GCGGGGGCGT CCAGCCCTAC CTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011512280.1

Translation

MSYPQGYLYQAPGSLALYSCPAYGASALAAPRSEELARSASGSAFSPYPGSAAFTAQAATGFGSPLQYSADAAAAAAGFPSYMGAPYDAHTTGMTGAISYHPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGDATRSKDESPDKAQEGTETSAEDEGISLHVDSLTDHSCSAESDGEKLPCRAGDPLCESGSECKDKYDDLEDDEDDDEEGERGLAPPKPVTSSPLTGLEAPLLSPPPEAAPRGGRKTPQGSRTSPGAPPPASKPKLWSLAEIATSDLKQPSLGPGCGPPGLPAAAAPASTGAPPGGSPYPASPLLGRPLYYTSPFYGNYTNYGNLNAALQGQGLLRYNSAAAAPGEALHTAPKAASDAGKAGAHPLESHYRSPGGGYEPKKDASEGCTVVGGGVQPYL

Target ORF information:

RefSeq Version	XM_011513978.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens iroquois homeobox 2 (IRX2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011513978.1

ORF Insert Sequence:

ATGTCCTACC CGCAGGGCTA CCTGTACCAG GCGCCCGGCT CGCTGGCGCT CTACTCGTGC 
CCGGCCTACG GCGCGTCGGC TTTGGCGGCT CCGCGCAGCG AGGAGCTGGC GCGCTCGGCG 
TCGGGCTCGG CGTTCAGCCC CTACCCGGGC TCGGCGGCCT TCACGGCGCA GGCGGCCACC 
GGCTTCGGGA GCCCGCTGCA GTACTCGGCC GACGCCGCCG CCGCCGCCGC CGGCTTCCCG 
TCCTACATGG GCGCACCCTA CGACGCGCAC ACCACCGGCA TGACCGGCGC CATCAGCTAC 
CACCCGTACG GCAGCGCGGC CTACCCGTAC CAGCTCAACG ACCCCGCGTA CCGCAAGAAC 
GCCACGCGGG ACGCCACGGC CACTCTCAAG GCCTGGCTCA ACGAGCACCG CAAGAACCCC 
TACCCCACCA AGGGCGAGAA GATCATGCTA GCCATCATCA CCAAGATGAC CCTCACCCAG 
GTCTCCACCT GGTTCGCCAA CGCGCGCCGG CGCCTCAAGA AGGAGAACAA GATGACCTGG 
GCCCCGAGAA ACAAAAGCGA AGATGAGGAC GAGGACGAGG GCGACGCTAC CAGAAGCAAG 
GACGAGAGTC CCGACAAGGC GCAGGAGGGC ACGGAGACCT CGGCAGAGGA CGAAGGGATC 
AGCCTGCACG TGGACTCGCT CACGGATCAC TCGTGCTCGG CCGAGTCGGA CGGGGAGAAG 
CTTCCGTGCC GCGCCGGGGA CCCCCTGTGC GAATCGGGCT CGGAGTGCAA GGACAAGTAT 
GACGACCTGG AGGACGACGA GGACGACGAC GAGGAGGGCG AGCGGGGCCT GGCGCCGCCC 
AAGCCCGTGA CCTCGTCGCC GCTTACCGGC TTGGAGGCGC CGCTGCTGAG CCCCCCGCCC 
GAGGCCGCGC CCCGCGGTGG CCGCAAGACG CCCCAGGGCA GCCGGACGTC TCCGGGCGCG 
CCGCCCCCCG CCAGCAAGCC CAAGCTGTGG TCGCTGGCCG AGATCGCCAC GTCGGACCTC 
AAGCAGCCGA GCCTGGGCCC GGGCTGCGGG CCACCGGGGC TGCCCGCGGC CGCCGCGCCG 
GCCTCAACCG GGGCACCGCC AGGAGGCTCG CCCTACCCTG CCTCGCCGCT GCTGGGCCGC 
CCCCTCTACT ACACGTCGCC CTTCTACGGC AACTACACAA ACTACGGGAA CTTGAACGCG 
GCGCTGCAGG GCCAGGGTCT CCTGCGGTAC AACTCTGCGG CCGCGGCCCC CGGCGAGGCC 
CTGCACACCG CGCCAAAGGC GGCCAGCGAC GCGGGCAAGG CGGGCGCGCA CCCGCTCGAG 
TCCCACTACC GGTCCCCGGG CGGCGGCTAC GAGCCCAAGA AAGATGCCAG CGAGGGCTGC 
ACCGTGGTTG GCGGGGGCGT CCAGCCCTAC CTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRX2 ( XM_011513979.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512281.1 Homo sapiens iroquois homeobox 2 (IRX2), transcript variant X2, mRNA.

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CloneID	OHu30549
Clone ID Related Accession (Same CDS sequence)	XM_011513978.1 , NM_001134222.2 , XM_011513979.2 , NM_001134222.1 , NM_033267.4 , XM_011513979.1 , NM_033267.5
Accession Version	XM_011513979.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1416bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	iroquois-class homeodomain protein IRX-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011513979.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCTACC CGCAGGGCTA CCTGTACCAG GCGCCCGGCT CGCTGGCGCT CTACTCGTGC 
CCGGCCTACG GCGCGTCGGC TTTGGCGGCT CCGCGCAGCG AGGAGCTGGC GCGCTCGGCG 
TCGGGCTCGG CGTTCAGCCC CTACCCGGGC TCGGCGGCCT TCACGGCGCA GGCGGCCACC 
GGCTTCGGGA GCCCGCTGCA GTACTCGGCC GACGCCGCCG CCGCCGCCGC CGGCTTCCCG 
TCCTACATGG GCGCACCCTA CGACGCGCAC ACCACCGGCA TGACCGGCGC CATCAGCTAC 
CACCCGTACG GCAGCGCGGC CTACCCGTAC CAGCTCAACG ACCCCGCGTA CCGCAAGAAC 
GCCACGCGGG ACGCCACGGC CACTCTCAAG GCCTGGCTCA ACGAGCACCG CAAGAACCCC 
TACCCCACCA AGGGCGAGAA GATCATGCTA GCCATCATCA CCAAGATGAC CCTCACCCAG 
GTCTCCACCT GGTTCGCCAA CGCGCGCCGG CGCCTCAAGA AGGAGAACAA GATGACCTGG 
GCCCCGAGAA ACAAAAGCGA AGATGAGGAC GAGGACGAGG GCGACGCTAC CAGAAGCAAG 
GACGAGAGTC CCGACAAGGC GCAGGAGGGC ACGGAGACCT CGGCAGAGGA CGAAGGGATC 
AGCCTGCACG TGGACTCGCT CACGGATCAC TCGTGCTCGG CCGAGTCGGA CGGGGAGAAG 
CTTCCGTGCC GCGCCGGGGA CCCCCTGTGC GAATCGGGCT CGGAGTGCAA GGACAAGTAT 
GACGACCTGG AGGACGACGA GGACGACGAC GAGGAGGGCG AGCGGGGCCT GGCGCCGCCC 
AAGCCCGTGA CCTCGTCGCC GCTTACCGGC TTGGAGGCGC CGCTGCTGAG CCCCCCGCCC 
GAGGCCGCGC CCCGCGGTGG CCGCAAGACG CCCCAGGGCA GCCGGACGTC TCCGGGCGCG 
CCGCCCCCCG CCAGCAAGCC CAAGCTGTGG TCGCTGGCCG AGATCGCCAC GTCGGACCTC 
AAGCAGCCGA GCCTGGGCCC GGGCTGCGGG CCACCGGGGC TGCCCGCGGC CGCCGCGCCG 
GCCTCAACCG GGGCACCGCC AGGAGGCTCG CCCTACCCTG CCTCGCCGCT GCTGGGCCGC 
CCCCTCTACT ACACGTCGCC CTTCTACGGC AACTACACAA ACTACGGGAA CTTGAACGCG 
GCGCTGCAGG GCCAGGGTCT CCTGCGGTAC AACTCTGCGG CCGCGGCCCC CGGCGAGGCC 
CTGCACACCG CGCCAAAGGC GGCCAGCGAC GCGGGCAAGG CGGGCGCGCA CCCGCTCGAG 
TCCCACTACC GGTCCCCGGG CGGCGGCTAC GAGCCCAAGA AAGATGCCAG CGAGGGCTGC 
ACCGTGGTTG GCGGGGGCGT CCAGCCCTAC CTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512281.1
CDS	170..1585
Translation	MSYPQGYLYQAPGSLALYSCPAYGASALAAPRSEELARSASGSAFSPYPGSAAFTAQAATGFGSPLQYSADAAAAAAGFPSYMGAPYDAHTTGMTGAISYHPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGDATRSKDESPDKAQEGTETSAEDEGISLHVDSLTDHSCSAESDGEKLPCRAGDPLCESGSECKDKYDDLEDDEDDDEEGERGLAPPKPVTSSPLTGLEAPLLSPPPEAAPRGGRKTPQGSRTSPGAPPPASKPKLWSLAEIATSDLKQPSLGPGCGPPGLPAAAAPASTGAPPGGSPYPASPLLGRPLYYTSPFYGNYTNYGNLNAALQGQGLLRYNSAAAAPGEALHTAPKAASDAGKAGAHPLESHYRSPGGGYEPKKDASEGCTVVGGGVQPYL

Target ORF information:

RefSeq Version	XM_011513979.2
Organism	Homo sapiens(human)
Definition	Homo sapiens iroquois homeobox 2 (IRX2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011513979.2

ORF Insert Sequence:

ATGTCCTACC CGCAGGGCTA CCTGTACCAG GCGCCCGGCT CGCTGGCGCT CTACTCGTGC 
CCGGCCTACG GCGCGTCGGC TTTGGCGGCT CCGCGCAGCG AGGAGCTGGC GCGCTCGGCG 
TCGGGCTCGG CGTTCAGCCC CTACCCGGGC TCGGCGGCCT TCACGGCGCA GGCGGCCACC 
GGCTTCGGGA GCCCGCTGCA GTACTCGGCC GACGCCGCCG CCGCCGCCGC CGGCTTCCCG 
TCCTACATGG GCGCACCCTA CGACGCGCAC ACCACCGGCA TGACCGGCGC CATCAGCTAC 
CACCCGTACG GCAGCGCGGC CTACCCGTAC CAGCTCAACG ACCCCGCGTA CCGCAAGAAC 
GCCACGCGGG ACGCCACGGC CACTCTCAAG GCCTGGCTCA ACGAGCACCG CAAGAACCCC 
TACCCCACCA AGGGCGAGAA GATCATGCTA GCCATCATCA CCAAGATGAC CCTCACCCAG 
GTCTCCACCT GGTTCGCCAA CGCGCGCCGG CGCCTCAAGA AGGAGAACAA GATGACCTGG 
GCCCCGAGAA ACAAAAGCGA AGATGAGGAC GAGGACGAGG GCGACGCTAC CAGAAGCAAG 
GACGAGAGTC CCGACAAGGC GCAGGAGGGC ACGGAGACCT CGGCAGAGGA CGAAGGGATC 
AGCCTGCACG TGGACTCGCT CACGGATCAC TCGTGCTCGG CCGAGTCGGA CGGGGAGAAG 
CTTCCGTGCC GCGCCGGGGA CCCCCTGTGC GAATCGGGCT CGGAGTGCAA GGACAAGTAT 
GACGACCTGG AGGACGACGA GGACGACGAC GAGGAGGGCG AGCGGGGCCT GGCGCCGCCC 
AAGCCCGTGA CCTCGTCGCC GCTTACCGGC TTGGAGGCGC CGCTGCTGAG CCCCCCGCCC 
GAGGCCGCGC CCCGCGGTGG CCGCAAGACG CCCCAGGGCA GCCGGACGTC TCCGGGCGCG 
CCGCCCCCCG CCAGCAAGCC CAAGCTGTGG TCGCTGGCCG AGATCGCCAC GTCGGACCTC 
AAGCAGCCGA GCCTGGGCCC GGGCTGCGGG CCACCGGGGC TGCCCGCGGC CGCCGCGCCG 
GCCTCAACCG GGGCACCGCC AGGAGGCTCG CCCTACCCTG CCTCGCCGCT GCTGGGCCGC 
CCCCTCTACT ACACGTCGCC CTTCTACGGC AACTACACAA ACTACGGGAA CTTGAACGCG 
GCGCTGCAGG GCCAGGGTCT CCTGCGGTAC AACTCTGCGG CCGCGGCCCC CGGCGAGGCC 
CTGCACACCG CGCCAAAGGC GGCCAGCGAC GCGGGCAAGG CGGGCGCGCA CCCGCTCGAG 
TCCCACTACC GGTCCCCGGG CGGCGGCTAC GAGCCCAAGA AAGATGCCAG CGAGGGCTGC 
ACCGTGGTTG GCGGGGGCGT CCAGCCCTAC CTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRX2 ( XM_011513979.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512281.1 Homo sapiens iroquois homeobox 2 (IRX2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu30549
Clone ID Related Accession (Same CDS sequence)	XM_011513978.1 , NM_001134222.2 , XM_011513979.2 , NM_001134222.1 , NM_033267.4 , XM_011513979.1 , NM_033267.5
Accession Version	XM_011513979.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1416bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	iroquois-class homeodomain protein IRX-2 isoform X1
Comment

ATGTCCTACC CGCAGGGCTA CCTGTACCAG GCGCCCGGCT CGCTGGCGCT CTACTCGTGC 
CCGGCCTACG GCGCGTCGGC TTTGGCGGCT CCGCGCAGCG AGGAGCTGGC GCGCTCGGCG 
TCGGGCTCGG CGTTCAGCCC CTACCCGGGC TCGGCGGCCT TCACGGCGCA GGCGGCCACC 
GGCTTCGGGA GCCCGCTGCA GTACTCGGCC GACGCCGCCG CCGCCGCCGC CGGCTTCCCG 
TCCTACATGG GCGCACCCTA CGACGCGCAC ACCACCGGCA TGACCGGCGC CATCAGCTAC 
CACCCGTACG GCAGCGCGGC CTACCCGTAC CAGCTCAACG ACCCCGCGTA CCGCAAGAAC 
GCCACGCGGG ACGCCACGGC CACTCTCAAG GCCTGGCTCA ACGAGCACCG CAAGAACCCC 
TACCCCACCA AGGGCGAGAA GATCATGCTA GCCATCATCA CCAAGATGAC CCTCACCCAG 
GTCTCCACCT GGTTCGCCAA CGCGCGCCGG CGCCTCAAGA AGGAGAACAA GATGACCTGG 
GCCCCGAGAA ACAAAAGCGA AGATGAGGAC GAGGACGAGG GCGACGCTAC CAGAAGCAAG 
GACGAGAGTC CCGACAAGGC GCAGGAGGGC ACGGAGACCT CGGCAGAGGA CGAAGGGATC 
AGCCTGCACG TGGACTCGCT CACGGATCAC TCGTGCTCGG CCGAGTCGGA CGGGGAGAAG 
CTTCCGTGCC GCGCCGGGGA CCCCCTGTGC GAATCGGGCT CGGAGTGCAA GGACAAGTAT 
GACGACCTGG AGGACGACGA GGACGACGAC GAGGAGGGCG AGCGGGGCCT GGCGCCGCCC 
AAGCCCGTGA CCTCGTCGCC GCTTACCGGC TTGGAGGCGC CGCTGCTGAG CCCCCCGCCC 
GAGGCCGCGC CCCGCGGTGG CCGCAAGACG CCCCAGGGCA GCCGGACGTC TCCGGGCGCG 
CCGCCCCCCG CCAGCAAGCC CAAGCTGTGG TCGCTGGCCG AGATCGCCAC GTCGGACCTC 
AAGCAGCCGA GCCTGGGCCC GGGCTGCGGG CCACCGGGGC TGCCCGCGGC CGCCGCGCCG 
GCCTCAACCG GGGCACCGCC AGGAGGCTCG CCCTACCCTG CCTCGCCGCT GCTGGGCCGC 
CCCCTCTACT ACACGTCGCC CTTCTACGGC AACTACACAA ACTACGGGAA CTTGAACGCG 
GCGCTGCAGG GCCAGGGTCT CCTGCGGTAC AACTCTGCGG CCGCGGCCCC CGGCGAGGCC 
CTGCACACCG CGCCAAAGGC GGCCAGCGAC GCGGGCAAGG CGGGCGCGCA CCCGCTCGAG 
TCCCACTACC GGTCCCCGGG CGGCGGCTAC GAGCCCAAGA AAGATGCCAG CGAGGGCTGC 
ACCGTGGTTG GCGGGGGCGT CCAGCCCTAC CTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011512281.1

Translation

MSYPQGYLYQAPGSLALYSCPAYGASALAAPRSEELARSASGSAFSPYPGSAAFTAQAATGFGSPLQYSADAAAAAAGFPSYMGAPYDAHTTGMTGAISYHPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGDATRSKDESPDKAQEGTETSAEDEGISLHVDSLTDHSCSAESDGEKLPCRAGDPLCESGSECKDKYDDLEDDEDDDEEGERGLAPPKPVTSSPLTGLEAPLLSPPPEAAPRGGRKTPQGSRTSPGAPPPASKPKLWSLAEIATSDLKQPSLGPGCGPPGLPAAAAPASTGAPPGGSPYPASPLLGRPLYYTSPFYGNYTNYGNLNAALQGQGLLRYNSAAAAPGEALHTAPKAASDAGKAGAHPLESHYRSPGGGYEPKKDASEGCTVVGGGVQPYL

Target ORF information:

RefSeq Version	XM_011513979.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens iroquois homeobox 2 (IRX2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011513979.1

ORF Insert Sequence:

ATGTCCTACC CGCAGGGCTA CCTGTACCAG GCGCCCGGCT CGCTGGCGCT CTACTCGTGC 
CCGGCCTACG GCGCGTCGGC TTTGGCGGCT CCGCGCAGCG AGGAGCTGGC GCGCTCGGCG 
TCGGGCTCGG CGTTCAGCCC CTACCCGGGC TCGGCGGCCT TCACGGCGCA GGCGGCCACC 
GGCTTCGGGA GCCCGCTGCA GTACTCGGCC GACGCCGCCG CCGCCGCCGC CGGCTTCCCG 
TCCTACATGG GCGCACCCTA CGACGCGCAC ACCACCGGCA TGACCGGCGC CATCAGCTAC 
CACCCGTACG GCAGCGCGGC CTACCCGTAC CAGCTCAACG ACCCCGCGTA CCGCAAGAAC 
GCCACGCGGG ACGCCACGGC CACTCTCAAG GCCTGGCTCA ACGAGCACCG CAAGAACCCC 
TACCCCACCA AGGGCGAGAA GATCATGCTA GCCATCATCA CCAAGATGAC CCTCACCCAG 
GTCTCCACCT GGTTCGCCAA CGCGCGCCGG CGCCTCAAGA AGGAGAACAA GATGACCTGG 
GCCCCGAGAA ACAAAAGCGA AGATGAGGAC GAGGACGAGG GCGACGCTAC CAGAAGCAAG 
GACGAGAGTC CCGACAAGGC GCAGGAGGGC ACGGAGACCT CGGCAGAGGA CGAAGGGATC 
AGCCTGCACG TGGACTCGCT CACGGATCAC TCGTGCTCGG CCGAGTCGGA CGGGGAGAAG 
CTTCCGTGCC GCGCCGGGGA CCCCCTGTGC GAATCGGGCT CGGAGTGCAA GGACAAGTAT 
GACGACCTGG AGGACGACGA GGACGACGAC GAGGAGGGCG AGCGGGGCCT GGCGCCGCCC 
AAGCCCGTGA CCTCGTCGCC GCTTACCGGC TTGGAGGCGC CGCTGCTGAG CCCCCCGCCC 
GAGGCCGCGC CCCGCGGTGG CCGCAAGACG CCCCAGGGCA GCCGGACGTC TCCGGGCGCG 
CCGCCCCCCG CCAGCAAGCC CAAGCTGTGG TCGCTGGCCG AGATCGCCAC GTCGGACCTC 
AAGCAGCCGA GCCTGGGCCC GGGCTGCGGG CCACCGGGGC TGCCCGCGGC CGCCGCGCCG 
GCCTCAACCG GGGCACCGCC AGGAGGCTCG CCCTACCCTG CCTCGCCGCT GCTGGGCCGC 
CCCCTCTACT ACACGTCGCC CTTCTACGGC AACTACACAA ACTACGGGAA CTTGAACGCG 
GCGCTGCAGG GCCAGGGTCT CCTGCGGTAC AACTCTGCGG CCGCGGCCCC CGGCGAGGCC 
CTGCACACCG CGCCAAAGGC GGCCAGCGAC GCGGGCAAGG CGGGCGCGCA CCCGCTCGAG 
TCCCACTACC GGTCCCCGGG CGGCGGCTAC GAGCCCAAGA AAGATGCCAG CGAGGGCTGC 
ACCGTGGTTG GCGGGGGCGT CCAGCCCTAC CTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Iroquois homeobox 2 suppresses cellular motility and chemokine expression in breast cancer cells.
BMC cancer15896(2015 Nov)
Werner S,Stamm H,Pandjaitan M,Kemming D,Brors B,Pantel K,Wikman H

IRX2-mediated upregulation of MMP-9 and VEGF in a PI3K/AKT-dependent manner.
Molecular medicine reports12(3)4346-51(2015 Sep)
Liu T,Zhou W,Cai B,Chu J,Shi G,Teng H,Xu J,Xiao J,Wang Y

Genome-wide association study of selenium concentrations.
Human molecular genetics24(5)1469-77(2015 Mar)
Cornelis MC,Fornage M,Foy M,Xun P,Gladyshev VN,Morris S,Chasman DI,Hu FB,Rimm EB,Kraft P,Jordan JM,Mozaffarian D,He K

Knockdown of IRX2 inhibits osteosarcoma cell proliferation and invasion by the AKT/MMP9 signaling pathway.
Molecular medicine reports10(1)169-74(2014 Jul)
Liu T,Zhou W,Zhang F,Shi G,Teng H,Xiao J,Wang Y

DNA-binding specificities of human transcription factors.
Cell152(1-2)327-39(2013 Jan)
Jolma A,Yan J,Whitington T,Toivonen J,Nitta KR,Rastas P,Morgunova E,Enge M,Taipale M,Wei G,Palin K,Vaquerizas JM,Vincentelli R,Luscombe NM,Hughes TR,Lemaire P,Ukkonen E,Kivioja T,Taipale J

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IRX2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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