WFDC5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	WFDC5
Entrez Gene ID	149708
Full Name	WAP four-disulfide core domain 5
Synonyms	PRG5,WAP1,dJ211D12.5
General protein information	Preferred Names WAP four-disulfide core domain 5 Names WAP four-disulfide core domain protein 5 p53-responsive gene 5 protein protease inhibitor WAP1 putative protease inhibitor WAP1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20q13.12
Summary	This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. Most WFDC proteins contain only one WFDC domain, and this encoded protein contains two WFDC domains. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. [provided by RefSeq, Jul 2008].
Disorder MIM:	605161

mRNA and Protein(s)

mRNA	Protein	Name
XM_011528601.1	XP_011526903.1	WAP four-disulfide core domain protein 5 isoform X1
NM_145652.3	NP_663627.1	WAP four-disulfide core domain protein 5 precursor
NM_145652.4	NP_663627.1	WAP four-disulfide core domain protein 5 precursor
XM_011528603.1	XP_011526905.1	WAP four-disulfide core domain protein 5 isoform X1
XM_011528602.1	XP_011526904.1	WAP four-disulfide core domain protein 5 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	WFDC5	NP_001129326.1
Mus musculus (house mouse)	Wfdc5	NP_663344.2
Rattus norvegicus (Norway rat)	Wfdc5	NP_001100008.1
Homo sapiens (human)	WFDC5	NP_663627.1
	WFDC5	NP_001162157.1
Bos taurus (cattle)	WFDC5	XP_002692375.1
Canis lupus familiaris (dog)	WFDC5	XP_853695.2

Gene Ontology
Bibliography

Related articles in PubMed

Reproduction and immunity-driven natural selection in the human WFDC locus.
Ferreira Z, Seixas S, Andr?s AM, Kretzschmar WW, Mullikin JC, Cherukuri PF, Cruz P, Swanson WJ, , Clark AG, Green ED, Hurle B
Molecular biology and evolution30(4)938-50(2013 Apr)

The C-terminal domain of the nuclear factor I-B2 isoform is glycosylated and transactivates the WAP gene in the JEG-3 cells.
Mukhopadhyay SS, Rosen JM
Biochemical and biophysical research communications358(3)770-6(2007 Jul)

Analysis of the promoter of mutated human whey acidic protein (WAP) gene.
Nukumi N, Seki M, Iwamori T, Yada T, Naito K, Tojo H
The Journal of reproduction and development52(2)315-20(2006 Apr)

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A
Genome research13(10)2265-70(2003 Oct)

A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic protein.
Clauss A, Lilja H, Lundwall A
The Biochemical journal368(Pt 1)233-42(2002 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

C-terminal domain of the nuclear factor I-B2 isoform is glycosylated and transactivates the WAP gene in tumor cells
Title: The C-terminal domain of the nuclear factor I-B2 isoform is glycosylated and transactivates the WAP gene in the JEG-3 cells.

analysis of promoter of mutated human whey acidic protein (WAP) gene
Title: Analysis of the promoter of mutated human whey acidic protein (WAP) gene.

The following WFDC5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the WFDC5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu01180	NM_145652.4 Latest version!	Homo sapiens WAP four-disulfide core domain 5 (WFDC5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu01180	XM_011528602.1 Latest version!	Homo sapiens WAP four-disulfide core domain 5 (WFDC5), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu01180	XM_011528603.1 Latest version!	Homo sapiens WAP four-disulfide core domain 5 (WFDC5), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu01180	XM_011528601.1 Latest version!	Homo sapiens WAP four-disulfide core domain 5 (WFDC5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu01180	NM_145652.3	Homo sapiens WAP four-disulfide core domain 5 (WFDC5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

WFDC5 ( NM_145652.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_663627.1 Homo sapiens WAP four-disulfide core domain 5 (WFDC5), mRNA.

Price & Availability↑

CloneID	OHu01180
Clone ID Related Accession (Same CDS sequence)	XM_011528601.1 , NM_145652.3 , NM_145652.4 , XM_011528603.1 , XM_011528602.1
Accession Version	NM_145652.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	WAP four-disulfide core domain protein 5 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY358822.1, BC039173.1 and Z93016.2. On Jun 18, 2011 this sequence version replaced NM_145652.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AY358822.1, BC039173.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2145893 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGACCC AGAGCCTTCT CCTCCTGGGG GCCCTCCTGG CTGTGGGGAG TCAGCTGCCT 
GCTGTCTTTG GCAGGAAGAA GGGAGAGAAA TCGGGGGGCT GCCCGCCAGA TGATGGGCCC 
TGCCTCCTAT CGGTGCCTGA CCAGTGCGTG GAAGACAGCC AGTGTCCCTT GACCAGGAAG 
TGCTGCTACA GAGCTTGCTT CCGCCAGTGT GTCCCCAGGG TCTCTGTGAA GCTGGGCAGC 
TGCCCAGAGG ACCAACTGCG CTGCCTCAGC CCCATGAACC ACCTGTGTCA CAAGGACTCA 
GACTGCTCGG GCAAAAAGCG ATGCTGCCAC AGCGCCTGCG GGCGGGATTG CCGGGATCCT 
GCCAGAGGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_663627.1
CDS	90..461
Translation	MRTQSLLLLGALLAVGSQLPAVFGRKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDPARG

Target ORF information:

RefSeq Version	NM_145652.3
Organism	Homo sapiens(human)
Definition	Homo sapiens WAP four-disulfide core domain 5 (WFDC5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145652.3

ORF Insert Sequence:

ATGAGGACCC AGAGCCTTCT CCTCCTGGGG GCCCTCCTGG CTGTGGGGAG TCAGCTGCCT 
GCTGTCTTTG GCAGGAAGAA GGGAGAGAAA TCGGGGGGCT GCCCGCCAGA TGATGGGCCC 
TGCCTCCTAT CGGTGCCTGA CCAGTGCGTG GAAGACAGCC AGTGTCCCTT GACCAGGAAG 
TGCTGCTACA GAGCTTGCTT CCGCCAGTGT GTCCCCAGGG TCTCTGTGAA GCTGGGCAGC 
TGCCCAGAGG ACCAACTGCG CTGCCTCAGC CCCATGAACC ACCTGTGTCA CAAGGACTCA 
GACTGCTCGG GCAAAAAGCG ATGCTGCCAC AGCGCCTGCG GGCGGGATTG CCGGGATCCT 
GCCAGAGGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WFDC5 ( NM_145652.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_663627.1 Homo sapiens WAP four-disulfide core domain 5 (WFDC5), mRNA.

Price & Availability↑

CloneID	OHu01180
Clone ID Related Accession (Same CDS sequence)	XM_011528601.1 , NM_145652.3 , NM_145652.4 , XM_011528603.1 , XM_011528602.1
Accession Version	NM_145652.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-01
Organism	Homo sapiens(human)
Product	WAP four-disulfide core domain protein 5 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from Z93016.2, AY358822.1 and BC039173.1. On Jun 2, 2019 this sequence version replaced NM_145652.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AY358822.1, BC039173.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2145893 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGGACCC AGAGCCTTCT CCTCCTGGGG GCCCTCCTGG CTGTGGGGAG TCAGCTGCCT 
GCTGTCTTTG GCAGGAAGAA GGGAGAGAAA TCGGGGGGCT GCCCGCCAGA TGATGGGCCC 
TGCCTCCTAT CGGTGCCTGA CCAGTGCGTG GAAGACAGCC AGTGTCCCTT GACCAGGAAG 
TGCTGCTACA GAGCTTGCTT CCGCCAGTGT GTCCCCAGGG TCTCTGTGAA GCTGGGCAGC 
TGCCCAGAGG ACCAACTGCG CTGCCTCAGC CCCATGAACC ACCTGTGTCA CAAGGACTCA 
GACTGCTCGG GCAAAAAGCG ATGCTGCCAC AGCGCCTGCG GGCGGGATTG CCGGGATCCT 
GCCAGAGGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_663627.1
CDS	92..463
Translation	MRTQSLLLLGALLAVGSQLPAVFGRKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDPARG

Target ORF information:

RefSeq Version	NM_145652.4
Organism	Homo sapiens(human)
Definition	Homo sapiens WAP four-disulfide core domain 5 (WFDC5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145652.4

ORF Insert Sequence:

ATGAGGACCC AGAGCCTTCT CCTCCTGGGG GCCCTCCTGG CTGTGGGGAG TCAGCTGCCT 
GCTGTCTTTG GCAGGAAGAA GGGAGAGAAA TCGGGGGGCT GCCCGCCAGA TGATGGGCCC 
TGCCTCCTAT CGGTGCCTGA CCAGTGCGTG GAAGACAGCC AGTGTCCCTT GACCAGGAAG 
TGCTGCTACA GAGCTTGCTT CCGCCAGTGT GTCCCCAGGG TCTCTGTGAA GCTGGGCAGC 
TGCCCAGAGG ACCAACTGCG CTGCCTCAGC CCCATGAACC ACCTGTGTCA CAAGGACTCA 
GACTGCTCGG GCAAAAAGCG ATGCTGCCAC AGCGCCTGCG GGCGGGATTG CCGGGATCCT 
GCCAGAGGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WFDC5 ( XM_011528601.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526903.1 Homo sapiens WAP four-disulfide core domain 5 (WFDC5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu01180
Clone ID Related Accession (Same CDS sequence)	XM_011528601.1 , NM_145652.3 , NM_145652.4 , XM_011528603.1 , XM_011528602.1
Accession Version	XM_011528601.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	WAP four-disulfide core domain protein 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGACCC AGAGCCTTCT CCTCCTGGGG GCCCTCCTGG CTGTGGGGAG TCAGCTGCCT 
GCTGTCTTTG GCAGGAAGAA GGGAGAGAAA TCGGGGGGCT GCCCGCCAGA TGATGGGCCC 
TGCCTCCTAT CGGTGCCTGA CCAGTGCGTG GAAGACAGCC AGTGTCCCTT GACCAGGAAG 
TGCTGCTACA GAGCTTGCTT CCGCCAGTGT GTCCCCAGGG TCTCTGTGAA GCTGGGCAGC 
TGCCCAGAGG ACCAACTGCG CTGCCTCAGC CCCATGAACC ACCTGTGTCA CAAGGACTCA 
GACTGCTCGG GCAAAAAGCG ATGCTGCCAC AGCGCCTGCG GGCGGGATTG CCGGGATCCT 
GCCAGAGGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526903.1
CDS	591..962
Translation	MRTQSLLLLGALLAVGSQLPAVFGRKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDPARG

Target ORF information:

RefSeq Version	XM_011528601.1
Organism	Homo sapiens(human)
Definition	Homo sapiens WAP four-disulfide core domain 5 (WFDC5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011528601.1

ORF Insert Sequence:

ATGAGGACCC AGAGCCTTCT CCTCCTGGGG GCCCTCCTGG CTGTGGGGAG TCAGCTGCCT 
GCTGTCTTTG GCAGGAAGAA GGGAGAGAAA TCGGGGGGCT GCCCGCCAGA TGATGGGCCC 
TGCCTCCTAT CGGTGCCTGA CCAGTGCGTG GAAGACAGCC AGTGTCCCTT GACCAGGAAG 
TGCTGCTACA GAGCTTGCTT CCGCCAGTGT GTCCCCAGGG TCTCTGTGAA GCTGGGCAGC 
TGCCCAGAGG ACCAACTGCG CTGCCTCAGC CCCATGAACC ACCTGTGTCA CAAGGACTCA 
GACTGCTCGG GCAAAAAGCG ATGCTGCCAC AGCGCCTGCG GGCGGGATTG CCGGGATCCT 
GCCAGAGGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WFDC5 ( XM_011528603.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526905.1 Homo sapiens WAP four-disulfide core domain 5 (WFDC5), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu01180
Clone ID Related Accession (Same CDS sequence)	XM_011528601.1 , NM_145652.3 , NM_145652.4 , XM_011528603.1 , XM_011528602.1
Accession Version	XM_011528603.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	WAP four-disulfide core domain protein 5 isoform X1
Comment

ATGAGGACCC AGAGCCTTCT CCTCCTGGGG GCCCTCCTGG CTGTGGGGAG TCAGCTGCCT 
GCTGTCTTTG GCAGGAAGAA GGGAGAGAAA TCGGGGGGCT GCCCGCCAGA TGATGGGCCC 
TGCCTCCTAT CGGTGCCTGA CCAGTGCGTG GAAGACAGCC AGTGTCCCTT GACCAGGAAG 
TGCTGCTACA GAGCTTGCTT CCGCCAGTGT GTCCCCAGGG TCTCTGTGAA GCTGGGCAGC 
TGCCCAGAGG ACCAACTGCG CTGCCTCAGC CCCATGAACC ACCTGTGTCA CAAGGACTCA 
GACTGCTCGG GCAAAAAGCG ATGCTGCCAC AGCGCCTGCG GGCGGGATTG CCGGGATCCT 
GCCAGAGGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526905.1
Translation	MRTQSLLLLGALLAVGSQLPAVFGRKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDPARG

Target ORF information:

RefSeq Version	XM_011528603.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens WAP four-disulfide core domain 5 (WFDC5), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011528603.1

ORF Insert Sequence:

ATGAGGACCC AGAGCCTTCT CCTCCTGGGG GCCCTCCTGG CTGTGGGGAG TCAGCTGCCT 
GCTGTCTTTG GCAGGAAGAA GGGAGAGAAA TCGGGGGGCT GCCCGCCAGA TGATGGGCCC 
TGCCTCCTAT CGGTGCCTGA CCAGTGCGTG GAAGACAGCC AGTGTCCCTT GACCAGGAAG 
TGCTGCTACA GAGCTTGCTT CCGCCAGTGT GTCCCCAGGG TCTCTGTGAA GCTGGGCAGC 
TGCCCAGAGG ACCAACTGCG CTGCCTCAGC CCCATGAACC ACCTGTGTCA CAAGGACTCA 
GACTGCTCGG GCAAAAAGCG ATGCTGCCAC AGCGCCTGCG GGCGGGATTG CCGGGATCCT 
GCCAGAGGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WFDC5 ( XM_011528602.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526904.1 Homo sapiens WAP four-disulfide core domain 5 (WFDC5), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu01180
Clone ID Related Accession (Same CDS sequence)	XM_011528601.1 , NM_145652.3 , NM_145652.4 , XM_011528603.1 , XM_011528602.1
Accession Version	XM_011528602.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	WAP four-disulfide core domain protein 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGACCC AGAGCCTTCT CCTCCTGGGG GCCCTCCTGG CTGTGGGGAG TCAGCTGCCT 
GCTGTCTTTG GCAGGAAGAA GGGAGAGAAA TCGGGGGGCT GCCCGCCAGA TGATGGGCCC 
TGCCTCCTAT CGGTGCCTGA CCAGTGCGTG GAAGACAGCC AGTGTCCCTT GACCAGGAAG 
TGCTGCTACA GAGCTTGCTT CCGCCAGTGT GTCCCCAGGG TCTCTGTGAA GCTGGGCAGC 
TGCCCAGAGG ACCAACTGCG CTGCCTCAGC CCCATGAACC ACCTGTGTCA CAAGGACTCA 
GACTGCTCGG GCAAAAAGCG ATGCTGCCAC AGCGCCTGCG GGCGGGATTG CCGGGATCCT 
GCCAGAGGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526904.1
CDS	399..770
Translation	MRTQSLLLLGALLAVGSQLPAVFGRKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDPARG

Target ORF information:

RefSeq Version	XM_011528602.1
Organism	Homo sapiens(human)
Definition	Homo sapiens WAP four-disulfide core domain 5 (WFDC5), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011528602.1

ORF Insert Sequence:

ATGAGGACCC AGAGCCTTCT CCTCCTGGGG GCCCTCCTGG CTGTGGGGAG TCAGCTGCCT 
GCTGTCTTTG GCAGGAAGAA GGGAGAGAAA TCGGGGGGCT GCCCGCCAGA TGATGGGCCC 
TGCCTCCTAT CGGTGCCTGA CCAGTGCGTG GAAGACAGCC AGTGTCCCTT GACCAGGAAG 
TGCTGCTACA GAGCTTGCTT CCGCCAGTGT GTCCCCAGGG TCTCTGTGAA GCTGGGCAGC 
TGCCCAGAGG ACCAACTGCG CTGCCTCAGC CCCATGAACC ACCTGTGTCA CAAGGACTCA 
GACTGCTCGG GCAAAAAGCG ATGCTGCCAC AGCGCCTGCG GGCGGGATTG CCGGGATCCT 
GCCAGAGGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Reproduction and immunity-driven natural selection in the human WFDC locus.
Molecular biology and evolution30(4)938-50(2013 Apr)
Ferreira Z,Seixas S,Andr?s AM,Kretzschmar WW,Mullikin JC,Cherukuri PF,Cruz P,Swanson WJ,,Clark AG,Green ED,Hurle B

The C-terminal domain of the nuclear factor I-B2 isoform is glycosylated and transactivates the WAP gene in the JEG-3 cells.
Biochemical and biophysical research communications358(3)770-6(2007 Jul)
Mukhopadhyay SS,Rosen JM

Analysis of the promoter of mutated human whey acidic protein (WAP) gene.
The Journal of reproduction and development52(2)315-20(2006 Apr)
Nukumi N,Seki M,Iwamori T,Yada T,Naito K,Tojo H

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Genome research13(10)2265-70(2003 Oct)
Clark HF,Gurney AL,Abaya E,Baker K,Baldwin D,Brush J,Chen J,Chow B,Chui C,Crowley C,Currell B,Deuel B,Dowd P,Eaton D,Foster J,Grimaldi C,Gu Q,Hass PE,Heldens S,Huang A,Kim HS,Klimowski L,Jin Y,Johnson S,Lee J,Lewis L,Liao D,Mark M,Robbie E,Sanchez C,Schoenfeld J,Seshagiri S,Simmons L,Singh J,Smith V,Stinson J,Vagts A,Vandlen R,Watanabe C,Wieand D,Woods K,Xie MH,Yansura D,Yi S,Yu G,Yuan J,Zhang M,Zhang Z,Goddard A,Wood WI,Godowski P,Gray A

A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic protein.
The Biochemical journal368(Pt 1)233-42(2002 Nov)
Clauss A,Lilja H,Lundwall A

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WFDC5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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