ALG10B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ALG10B
Entrez Gene ID	144245
Full Name	ALG10B, alpha-1,2-glucosyltransferase
Synonyms	ALG10,KCR1
General protein information	Preferred Names ALG10B, alpha-1,2-glucosyltransferase Names putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase alpha-1,2-glucosyltransferase ALG10-A alpha-2-glucosyltransferase ALG10-B asparagine-linked glycosylation 10 homolog B (yeast, alpha-1,2-glucosyltransferase) asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B asparagine-linked glycosylation protein 10 homolog B dolichyl-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-dolichol alpha-1,2- glucosyltransferase modifier of the HERG potassium channel potassium channel regulator 1 putative alpha-1,2-glucosyltransferase ALG10-B
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001013620.3	NP_001013642.1	putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase isoform 1
NM_001013620.4	NP_001013642.2	putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase isoform 1
NM_001308340.1	NP_001295269.1	putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase isoform 2
XM_005268665.4	XP_005268722.1	putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase isoform X1
NM_001308340.2	NP_001295269.2	putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase isoform 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	ALG10B	NP_001013642.1
Caenorhabditis elegans (roundworm)	tag-179	NP_492634.2
Pan troglodytes (chimpanzee)	ALG10B	XP_001169000.1
	ALG10B	XP_001086837.1

Gene Ontology
Bibliography

Related articles in PubMed

A KCR1 variant implicated in susceptibility to the long QT syndrome.
Hayashi K, Fujino N, Ino H, Uchiyama K, Sakata K, Konno T, Masuta E, Funada A, Sakamoto Y, Tsubokawa T, Hodatsu A, Yasuda T, Kanaya H, Kim MY, Kupershmidt S, Higashida H, Yamagishi M
Journal of molecular and cellular cardiology50(1)50-7(2011 Jan)

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.
Daly AK, Donaldson PT, Bhatnagar P, Shen Y, Pe'er I, Floratos A, Daly MJ, Goldstein DB, John S, Nelson MR, Graham J, Park BK, Dillon JF, Bernal W, Cordell HJ, Pirmohamed M, Aithal GP, Day CP, ,
Nature genetics41(7)816-9(2009 Jul)

In vivo identification of genes that modify ether-a-go-go-related gene activity in Caenorhabditis elegans may also affect human cardiac arrhythmia.
Petersen CI, McFarland TR, Stepanovic SZ, Yang P, Reiner DJ, Hayashi K, George AL, Roden DM, Thomas JH, Balser JR
Proceedings of the National Academy of Sciences of the United States of America101(32)11773-8(2004 Aug)

The IKr drug response is modulated by KCR1 in transfected cardiac and noncardiac cell lines.
Kupershmidt S, Yang IC, Hayashi K, Wei J, Chanthaphaychith S, Petersen CI, Johns DC, George AL Jr, Roden DM, Balser JR
FASEB journal : official publication of the Federation of American Societies for Experimental Biology17(15)2263-5(2003 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Findings suggest that KCR1 genetic variations that diminish the ability of KCR1 to protect KCNH2 from inhibition by commonly used therapeutic agents constitute a risk factor for the aLQTS.
Title: A KCR1 variant implicated in susceptibility to the long QT syndrome.

The following ALG10B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ALG10B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30757	NM_001013620.3 Latest version!	Homo sapiens ALG10B, alpha-1,2-glucosyltransferase (ALG10B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu76083	NM_001308340.1 Latest version!	Homo sapiens ALG10 alpha-1,2-glucosyltransferase B (ALG10B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu46327	XM_005268665.4 Latest version!	Homo sapiens ALG10 alpha-1,2-glucosyltransferase B (ALG10B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu107245	NM_001013620.4 Latest version!	Homo sapiens ALG10 alpha-1,2-glucosyltransferase B (ALG10B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu108222	NM_001308340.2 Latest version!	Homo sapiens ALG10 alpha-1,2-glucosyltransferase B (ALG10B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ALG10B ( NM_001013620.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001013642.1 Homo sapiens ALG10B, alpha-1,2-glucosyltransferase (ALG10B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30757
Clone ID Related Accession (Same CDS sequence)	NM_001013620.3
Accession Version	NM_001013620.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1422bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB254106.1, AY845858.1, AC117372.2 and BQ024224.1. On Apr 20, 2007 this sequence version replaced NM_001013620.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: DB254106.1, SRR1163655.398127.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGCAGC TAGAGGGTTA CTGTTTCTCG GCCGCCTTGA GCTGTACCTT TTTAGTGTCC 
TGCCTCCTCT TCTCCGCCTT CAGCCGGGCG CTGCGAGAGC CCTACATGGA CGAGATCTTC 
CACCTGCCTC AGGCGCAGCG CTACTGTGAG GGCCATTTCT CCCTTTCCCA GTGGGATCCC 
ATGATTACTA CATTACCTGG CTTGTACCTG GTGTCAGTTG GAGTGGTCAA ACCTGCCATT 
TGGATCTTTG GATGGTCTGA ACATGTTGTC TGCTCCATTG GGATGCTCAG ATTTGTTAAT 
CTTCTCTTCA GTGTTGGCAA CTTCTATTTA CTATATTTGC TTTTCCACAA GGTACAACCC 
AGAAACAAGG CTGCCTCAAG TATCCAGAGA GTCTTGTCAA CATTAACACT AGCAGTATTT 
CCAACACTTT ATTTTTTTAA CTTCCTTTAT TATACAGAAG CAGGATCTAT GTTTTTTACT 
CTTTTTGCAT ATTTGATGTG TCTTTATGGA AATCATAAAA CTTCAGCCTT CCTTGGATTT 
TGTGGCTTCA TGTTTCGGCA AACAAATATC ATCTGGGCTG TCTTCTGTGC AGGGAATGTC 
ATTGCACAAA AGTTAACTGA GGCTTGGAAA ACTGAGCTAC AAAAGAAGGA AGACAGACTT 
CCACCTATTA AAGGACCATT TGCAGAATTC AGAAAAATTC TTCAGTTTCT TTTGGCTTAT 
TCCATGTCCT TTAAAAACTT GAGTATGCTT TTCTGTTTGA CTTGGCCCTA CATCCTTCTG 
GGATTTCTGT TTTGTGCTTT TGTAGTAGTT AATGGTGGAA TTGTTATTGG CGATCGGAGT 
AGTCATGAAG CCTGTCTTCA TTTTCCTCAA CTATTCTACT TTTTTTCATT TACTCTCTTT 
TTTTCTTTTC CTCATCTCCT GTCTCCTAGC AAAATTAAGA CTTTTCTTTC CTTAGTTTGG 
AAACATGGAA TTCTGTTTTT GGTGGTTACC TTAGTCTCTG TGTTTTTAGT TTGGAAATTC 
ACTTATGCTC ATAAATACTT GCTAGCAGAC AATAGACATT ATACTTTCTA TGTGTGGAAA 
AGAGTTTTTC AAAGATATGC AATTCTGAAA TATTTGTTAG TTCCAGCCTA TATATTTGCT 
GGTTGGAGTA TAGCTGACTC ATTGAAATCA AAGCCAATTT TTTGGAATTT AATGTTTTTC 
ATATGCTTGT TCATTGTTAT AGTTCCTCAG AAACTGCTGG AATTTCGTTA CTTCATTTTA 
CCTTATGTCA TTTATAGGCT TAACATAACT CTGCCTCCCA CATCCAGACT TGTTTGTGAA 
CTGAGTTGCT ATGCAATTGT TAATTTCATA ACTTTTTACA TCTTTCTGAA CAAGACTTTT 
CAGTGGCCAA ATAGTCAGGA CATTCAAAGG TTTATGTGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001013642.1
CDS	140..1561
Translation	MAQLEGYCFSAALSCTFLVSCLLFSAFSRALREPYMDEIFHLPQAQRYCEGHFSLSQWDPMITTLPGLYLVSVGVVKPAIWIFGWSEHVVCSIGMLRFVNLLFSVGNFYLLYLLFHKVQPRNKAASSIQRVLSTLTLAVFPTLYFFNFLYYTEAGSMFFTLFAYLMCLYGNHKTSAFLGFCGFMFRQTNIIWAVFCAGNVIAQKLTEAWKTELQKKEDRLPPIKGPFAEFRKILQFLLAYSMSFKNLSMLFCLTWPYILLGFLFCAFVVVNGGIVIGDRSSHEACLHFPQLFYFFSFTLFFSFPHLLSPSKIKTFLSLVWKHGILFLVVTLVSVFLVWKFTYAHKYLLADNRHYTFYVWKRVFQRYAILKYLLVPAYIFAGWSIADSLKSKPIFWNLMFFICLFIVIVPQKLLEFRYFILPYVIYRLNITLPPTSRLVCELSCYAIVNFITFYIFLNKTFQWPNSQDIQRFMW

Target ORF information:

RefSeq Version	NM_001013620.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ALG10B, alpha-1,2-glucosyltransferase (ALG10B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001013620.3

ORF Insert Sequence:

ATGGCGCAGC TAGAGGGTTA CTGTTTCTCG GCCGCCTTGA GCTGTACCTT TTTAGTGTCC 
TGCCTCCTCT TCTCCGCCTT CAGCCGGGCG CTGCGAGAGC CCTACATGGA CGAGATCTTC 
CACCTGCCTC AGGCGCAGCG CTACTGTGAG GGCCATTTCT CCCTTTCCCA GTGGGATCCC 
ATGATTACTA CATTACCTGG CTTGTACCTG GTGTCAGTTG GAGTGGTCAA ACCTGCCATT 
TGGATCTTTG GATGGTCTGA ACATGTTGTC TGCTCCATTG GGATGCTCAG ATTTGTTAAT 
CTTCTCTTCA GTGTTGGCAA CTTCTATTTA CTATATTTGC TTTTCCACAA GGTACAACCC 
AGAAACAAGG CTGCCTCAAG TATCCAGAGA GTCTTGTCAA CATTAACACT AGCAGTATTT 
CCAACACTTT ATTTTTTTAA CTTCCTTTAT TATACAGAAG CAGGATCTAT GTTTTTTACT 
CTTTTTGCAT ATTTGATGTG TCTTTATGGA AATCATAAAA CTTCAGCCTT CCTTGGATTT 
TGTGGCTTCA TGTTTCGGCA AACAAATATC ATCTGGGCTG TCTTCTGTGC AGGGAATGTC 
ATTGCACAAA AGTTAACTGA GGCTTGGAAA ACTGAGCTAC AAAAGAAGGA AGACAGACTT 
CCACCTATTA AAGGACCATT TGCAGAATTC AGAAAAATTC TTCAGTTTCT TTTGGCTTAT 
TCCATGTCCT TTAAAAACTT GAGTATGCTT TTCTGTTTGA CTTGGCCCTA CATCCTTCTG 
GGATTTCTGT TTTGTGCTTT TGTAGTAGTT AATGGTGGAA TTGTTATTGG CGATCGGAGT 
AGTCATGAAG CCTGTCTTCA TTTTCCTCAA CTATTCTACT TTTTTTCATT TACTCTCTTT 
TTTTCTTTTC CTCATCTCCT GTCTCCTAGC AAAATTAAGA CTTTTCTTTC CTTAGTTTGG 
AAACATGGAA TTCTGTTTTT GGTGGTTACC TTAGTCTCTG TGTTTTTAGT TTGGAAATTC 
ACTTATGCTC ATAAATACTT GCTAGCAGAC AATAGACATT ATACTTTCTA TGTGTGGAAA 
AGAGTTTTTC AAAGATATGC AATTCTGAAA TATTTGTTAG TTCCAGCCTA TATATTTGCT 
GGTTGGAGTA TAGCTGACTC ATTGAAATCA AAGCCAATTT TTTGGAATTT AATGTTTTTC 
ATATGCTTGT TCATTGTTAT AGTTCCTCAG AAACTGCTGG AATTTCGTTA CTTCATTTTA 
CCTTATGTCA TTTATAGGCT TAACATAACT CTGCCTCCCA CATCCAGACT TGTTTGTGAA 
CTGAGTTGCT ATGCAATTGT TAATTTCATA ACTTTTTACA TCTTTCTGAA CAAGACTTTT 
CAGTGGCCAA ATAGTCAGGA CATTCAAAGG TTTATGTGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALG10B ( NM_001308340.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001295269.1 Homo sapiens ALG10 alpha-1,2-glucosyltransferase B (ALG10B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu76083
Clone ID Related Accession (Same CDS sequence)	NM_001308340.1
Accession Version	NM_001308340.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-10
Organism	Homo sapiens(human)
Product	putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB254106.1, AL712776.1, AC117372.2 and BQ024224.1. On Apr 30, 2015 this sequence version replaced XM_011537948.1. Transcript Variant: This variant (2) uses an alternate splice site in its 3' coding region, which results in a frameshift, compared to variant 1. It encodes isoform 2, which has a shorter and distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.78151.1, AL712776.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGCAGC TAGAGGGTTA CTGTTTCTCG GCCGCCTTGA GCTGTACCTT TTTAGTGTCC 
TGCCTCCTCT TCTCCGCCTT CAGCCGGGCG CTGCGAGAGC CCTACATGGA CGAGATCTTC 
CACCTGCCTC AGGCGCAGCG CTACTGTGAG GGCCATTTCT CCCTTTCCCA GTGGGATCCC 
ATGATTACTA CATTACCTGG CTTGTACCTG GTGTCAGTTG GAGTGGTCAA ACCTGCCATT 
TGGATCTTTG GATGGTCTGA ACATGTTGTC TGCTCCATTG GGATGCTCAG ATTTGTTAAT 
CTTCTCTTCA GTGTTGGCAA CTTCTATTTA CTATATTTGC TTTTCCACAA GGTACAACCC 
AGAAACAAGG AATACTTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001295269.1
CDS	140..520
Translation	MAQLEGYCFSAALSCTFLVSCLLFSAFSRALREPYMDEIFHLPQAQRYCEGHFSLSQWDPMITTLPGLYLVSVGVVKPAIWIFGWSEHVVCSIGMLRFVNLLFSVGNFYLLYLLFHKVQPRNKEYF

Target ORF information:

RefSeq Version	NM_001308340.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ALG10 alpha-1,2-glucosyltransferase B (ALG10B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001308340.1

ORF Insert Sequence:

ATGGCGCAGC TAGAGGGTTA CTGTTTCTCG GCCGCCTTGA GCTGTACCTT TTTAGTGTCC 
TGCCTCCTCT TCTCCGCCTT CAGCCGGGCG CTGCGAGAGC CCTACATGGA CGAGATCTTC 
CACCTGCCTC AGGCGCAGCG CTACTGTGAG GGCCATTTCT CCCTTTCCCA GTGGGATCCC 
ATGATTACTA CATTACCTGG CTTGTACCTG GTGTCAGTTG GAGTGGTCAA ACCTGCCATT 
TGGATCTTTG GATGGTCTGA ACATGTTGTC TGCTCCATTG GGATGCTCAG ATTTGTTAAT 
CTTCTCTTCA GTGTTGGCAA CTTCTATTTA CTATATTTGC TTTTCCACAA GGTACAACCC 
AGAAACAAGG AATACTTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALG10B ( XM_005268665.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005268722.1 Homo sapiens ALG10 alpha-1,2-glucosyltransferase B (ALG10B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu46327
Clone ID Related Accession (Same CDS sequence)	XM_005268665.4
Accession Version	XM_005268665.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1242bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005268665.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTACTA CATTACCTGG CTTGTACCTG GTGTCAGTTG GAGTGGTCAA ACCTGCCATT 
TGGATCTTTG CATGGTCTGA ACATGTTGTC TGCTCCATTG GGATGCTCAG ATTTGTTAAT 
CTTCTCTTCA GTGTTGGCAA CTTCTATTTA CTATATTTGC TTTTCCACAA GGTACAACCC 
AGAAACAAGG CTGCCTCAAG TATCCAGAGA GTCTTGTCAA CATTAACACT AGCAGTATTT 
CCAACACTTT ATTTTTTTAA CTTCCTTTAT TATACAGAAG CAGGATCTAT GTTTTTTACT 
CTTTTTGCAT ATTTGATGTG TCTTTATGGA AATCATAAAA CTTCAGCCTT CCTTGGATTT 
TGTGGCTTCA TGTTTCGGCA AACAAATATC ATCTGGGCTG TCTTCTGTGC AGGGAATGTC 
ATTGCACAAA AGTTAACTGA GGCTTGGAAA ACTGAGCTAC AAAAGAAGGA AGACAGACTT 
CCACCTATTA AAGGACCATT TGCAGAATTC AGAAAAATTC TTCAGTTTCT TTTGGCTTAT 
TCCATGTCCT TTAAAAACTT GAGTATGCTT TTCTGTTTGA CTTGGCCCTA CATCCTTCTG 
GGATTTCTGT TTTGTGCTTT TGTAGTAGTT AATGGTGGAA TTGTTATTGG CGATCGGAGT 
AGTCATGAAG CCTGTCTTCA TTTTCCTCAA CTATTCTACT TTTTTTCATT TACTCTCTTT 
TTTTCTTTTC CTCATCTCCT GTCTCCTAGC AAAATTAAGA CTTTTCTTTC CTTAGTTTGG 
AAACATGGAA TTCTGTTTTT GGTGGTTACC TTAGTCTCTG TGTTTTTAGT TTGGAAATTC 
ACTTATGCTC ATAAATACTT GCTAGCAGAC AATAGACATT ATACTTTCTA TGTGTGGAAA 
AGAGTTTTTC AAAGATATGC AATTCTGAAA TATTTGTTAG TTCCAGCCTA TATATTTGCT 
GGTTGGAGTA TAGCTGACTC ATTGAAATCA AAGCCAATTT TTTGGAATTT AATGTTTTTC 
ATATGCTTGT TCATTGTTAT AGTTCCTCAG AAACTGCTGG AATTTCGTTA CTTCATTTTA 
CCTTATGTCA TTTATAGGCT TAACATAACT CTGCCTCCCA CATCCAGACT TGTTTGTGAA 
CTGAGTTGCT ATGCAATTGT TAATTTCATA ACTTTTTACA TCTTTCTGAA CAAGACTTTT 
CAGTGGCCAA ATAGTCAGGA CATTCAAAGG TTTATGTGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005268722.1
CDS	101..1342
Translation	MITTLPGLYLVSVGVVKPAIWIFAWSEHVVCSIGMLRFVNLLFSVGNFYLLYLLFHKVQPRNKAASSIQRVLSTLTLAVFPTLYFFNFLYYTEAGSMFFTLFAYLMCLYGNHKTSAFLGFCGFMFRQTNIIWAVFCAGNVIAQKLTEAWKTELQKKEDRLPPIKGPFAEFRKILQFLLAYSMSFKNLSMLFCLTWPYILLGFLFCAFVVVNGGIVIGDRSSHEACLHFPQLFYFFSFTLFFSFPHLLSPSKIKTFLSLVWKHGILFLVVTLVSVFLVWKFTYAHKYLLADNRHYTFYVWKRVFQRYAILKYLLVPAYIFAGWSIADSLKSKPIFWNLMFFICLFIVIVPQKLLEFRYFILPYVIYRLNITLPPTSRLVCELSCYAIVNFITFYIFLNKTFQWPNSQDIQRFMW

Target ORF information:

RefSeq Version	XM_005268665.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ALG10 alpha-1,2-glucosyltransferase B (ALG10B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005268665.4

ORF Insert Sequence:

ATGATTACTA CATTACCTGG CTTGTACCTG GTGTCAGTTG GAGTGGTCAA ACCTGCCATT 
TGGATCTTTG CATGGTCTGA ACATGTTGTC TGCTCCATTG GGATGCTCAG ATTTGTTAAT 
CTTCTCTTCA GTGTTGGCAA CTTCTATTTA CTATATTTGC TTTTCCACAA GGTACAACCC 
AGAAACAAGG CTGCCTCAAG TATCCAGAGA GTCTTGTCAA CATTAACACT AGCAGTATTT 
CCAACACTTT ATTTTTTTAA CTTCCTTTAT TATACAGAAG CAGGATCTAT GTTTTTTACT 
CTTTTTGCAT ATTTGATGTG TCTTTATGGA AATCATAAAA CTTCAGCCTT CCTTGGATTT 
TGTGGCTTCA TGTTTCGGCA AACAAATATC ATCTGGGCTG TCTTCTGTGC AGGGAATGTC 
ATTGCACAAA AGTTAACTGA GGCTTGGAAA ACTGAGCTAC AAAAGAAGGA AGACAGACTT 
CCACCTATTA AAGGACCATT TGCAGAATTC AGAAAAATTC TTCAGTTTCT TTTGGCTTAT 
TCCATGTCCT TTAAAAACTT GAGTATGCTT TTCTGTTTGA CTTGGCCCTA CATCCTTCTG 
GGATTTCTGT TTTGTGCTTT TGTAGTAGTT AATGGTGGAA TTGTTATTGG CGATCGGAGT 
AGTCATGAAG CCTGTCTTCA TTTTCCTCAA CTATTCTACT TTTTTTCATT TACTCTCTTT 
TTTTCTTTTC CTCATCTCCT GTCTCCTAGC AAAATTAAGA CTTTTCTTTC CTTAGTTTGG 
AAACATGGAA TTCTGTTTTT GGTGGTTACC TTAGTCTCTG TGTTTTTAGT TTGGAAATTC 
ACTTATGCTC ATAAATACTT GCTAGCAGAC AATAGACATT ATACTTTCTA TGTGTGGAAA 
AGAGTTTTTC AAAGATATGC AATTCTGAAA TATTTGTTAG TTCCAGCCTA TATATTTGCT 
GGTTGGAGTA TAGCTGACTC ATTGAAATCA AAGCCAATTT TTTGGAATTT AATGTTTTTC 
ATATGCTTGT TCATTGTTAT AGTTCCTCAG AAACTGCTGG AATTTCGTTA CTTCATTTTA 
CCTTATGTCA TTTATAGGCT TAACATAACT CTGCCTCCCA CATCCAGACT TGTTTGTGAA 
CTGAGTTGCT ATGCAATTGT TAATTTCATA ACTTTTTACA TCTTTCTGAA CAAGACTTTT 
CAGTGGCCAA ATAGTCAGGA CATTCAAAGG TTTATGTGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALG10B ( NM_001013620.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001013642.2 Homo sapiens ALG10 alpha-1,2-glucosyltransferase B (ALG10B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu107245
Clone ID Related Accession (Same CDS sequence)	NM_001013620.4
Accession Version	NM_001013620.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1422bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC117372.2. On Nov 23, 2018 this sequence version replaced NM_001013620.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.398127.1, SRR1163657.499250.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000308742.9/ ENSP00000310120.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGCAGC TAGAGGGTTA CTGTTTCTCG GCCGCCTTGA GCTGTACCTT TTTAGTGTCC 
TGCCTCCTCT TCTCCGCCTT CAGCCGGGCG CTGCGAGAGC CCTACATGGA CGAGATCTTC 
CACCTGCCTC AGGCGCAGCG CTACTGTGAG GGCCATTTCT CCCTTTCCCA GTGGGATCCC 
ATGATTACTA CATTACCTGG CTTGTACCTG GTGTCAGTTG GAGTGGTCAA ACCTGCCATT 
TGGATCTTTG CATGGTCTGA ACATGTTGTC TGCTCCATTG GGATGCTCAG ATTTGTTAAT 
CTTCTCTTCA GTGTTGGCAA CTTCTATTTA CTATATTTGC TTTTCCACAA GGTACAACCC 
AGAAACAAGG CTGCCTCAAG TATCCAGAGA GTCTTGTCAA CATTAACACT AGCAGTATTT 
CCAACACTTT ATTTTTTTAA CTTCCTTTAT TATACAGAAG CAGGATCTAT GTTTTTTACT 
CTTTTTGCAT ATTTGATGTG TCTTTATGGA AATCATAAAA CTTCAGCCTT CCTTGGATTT 
TGTGGCTTCA TGTTTCGGCA AACAAATATC ATCTGGGCTG TCTTCTGTGC AGGGAATGTC 
ATTGCACAAA AGTTAACTGA GGCTTGGAAA ACTGAGCTAC AAAAGAAGGA AGACAGACTT 
CCACCTATTA AAGGACCATT TGCAGAATTC AGAAAAATTC TTCAGTTTCT TTTGGCTTAT 
TCCATGTCCT TTAAAAACTT GAGTATGCTT TTCTGTTTGA CTTGGCCCTA CATCCTTCTG 
GGATTTCTGT TTTGTGCTTT TGTAGTAGTT AATGGTGGAA TTGTTATTGG CGATCGGAGT 
AGTCATGAAG CCTGTCTTCA TTTTCCTCAA CTATTCTACT TTTTTTCATT TACTCTCTTT 
TTTTCTTTTC CTCATCTCCT GTCTCCTAGC AAAATTAAGA CTTTTCTTTC CTTAGTTTGG 
AAACATGGAA TTCTGTTTTT GGTGGTTACC TTAGTCTCTG TGTTTTTAGT TTGGAAATTC 
ACTTATGCTC ATAAATACTT GCTAGCAGAC AATAGACATT ATACTTTCTA TGTGTGGAAA 
AGAGTTTTTC AAAGATATGC AATTCTGAAA TATTTGTTAG TTCCAGCCTA TATATTTGCT 
GGTTGGAGTA TAGCTGACTC ATTGAAATCA AAGCCAATTT TTTGGAATTT AATGTTTTTC 
ATATGCTTGT TCATTGTTAT AGTTCCTCAG AAACTGCTGG AATTTCGTTA CTTCATTTTA 
CCTTATGTCA TTTATAGGCT TAACATAACT CTGCCTCCCA CATCCAGACT TGTTTGTGAA 
CTGAGTTGCT ATGCAATTGT TAATTTCATA ACTTTTTACA TCTTTCTGAA CAAGACTTTT 
CAGTGGCCAA ATAGTCAGGA CATTCAAAGG TTTATGTGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001013642.2
CDS	121..1542
Translation	MAQLEGYCFSAALSCTFLVSCLLFSAFSRALREPYMDEIFHLPQAQRYCEGHFSLSQWDPMITTLPGLYLVSVGVVKPAIWIFAWSEHVVCSIGMLRFVNLLFSVGNFYLLYLLFHKVQPRNKAASSIQRVLSTLTLAVFPTLYFFNFLYYTEAGSMFFTLFAYLMCLYGNHKTSAFLGFCGFMFRQTNIIWAVFCAGNVIAQKLTEAWKTELQKKEDRLPPIKGPFAEFRKILQFLLAYSMSFKNLSMLFCLTWPYILLGFLFCAFVVVNGGIVIGDRSSHEACLHFPQLFYFFSFTLFFSFPHLLSPSKIKTFLSLVWKHGILFLVVTLVSVFLVWKFTYAHKYLLADNRHYTFYVWKRVFQRYAILKYLLVPAYIFAGWSIADSLKSKPIFWNLMFFICLFIVIVPQKLLEFRYFILPYVIYRLNITLPPTSRLVCELSCYAIVNFITFYIFLNKTFQWPNSQDIQRFMW

Target ORF information:

RefSeq Version	NM_001013620.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ALG10 alpha-1,2-glucosyltransferase B (ALG10B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001013620.4

ORF Insert Sequence:

ATGGCGCAGC TAGAGGGTTA CTGTTTCTCG GCCGCCTTGA GCTGTACCTT TTTAGTGTCC 
TGCCTCCTCT TCTCCGCCTT CAGCCGGGCG CTGCGAGAGC CCTACATGGA CGAGATCTTC 
CACCTGCCTC AGGCGCAGCG CTACTGTGAG GGCCATTTCT CCCTTTCCCA GTGGGATCCC 
ATGATTACTA CATTACCTGG CTTGTACCTG GTGTCAGTTG GAGTGGTCAA ACCTGCCATT 
TGGATCTTTG CATGGTCTGA ACATGTTGTC TGCTCCATTG GGATGCTCAG ATTTGTTAAT 
CTTCTCTTCA GTGTTGGCAA CTTCTATTTA CTATATTTGC TTTTCCACAA GGTACAACCC 
AGAAACAAGG CTGCCTCAAG TATCCAGAGA GTCTTGTCAA CATTAACACT AGCAGTATTT 
CCAACACTTT ATTTTTTTAA CTTCCTTTAT TATACAGAAG CAGGATCTAT GTTTTTTACT 
CTTTTTGCAT ATTTGATGTG TCTTTATGGA AATCATAAAA CTTCAGCCTT CCTTGGATTT 
TGTGGCTTCA TGTTTCGGCA AACAAATATC ATCTGGGCTG TCTTCTGTGC AGGGAATGTC 
ATTGCACAAA AGTTAACTGA GGCTTGGAAA ACTGAGCTAC AAAAGAAGGA AGACAGACTT 
CCACCTATTA AAGGACCATT TGCAGAATTC AGAAAAATTC TTCAGTTTCT TTTGGCTTAT 
TCCATGTCCT TTAAAAACTT GAGTATGCTT TTCTGTTTGA CTTGGCCCTA CATCCTTCTG 
GGATTTCTGT TTTGTGCTTT TGTAGTAGTT AATGGTGGAA TTGTTATTGG CGATCGGAGT 
AGTCATGAAG CCTGTCTTCA TTTTCCTCAA CTATTCTACT TTTTTTCATT TACTCTCTTT 
TTTTCTTTTC CTCATCTCCT GTCTCCTAGC AAAATTAAGA CTTTTCTTTC CTTAGTTTGG 
AAACATGGAA TTCTGTTTTT GGTGGTTACC TTAGTCTCTG TGTTTTTAGT TTGGAAATTC 
ACTTATGCTC ATAAATACTT GCTAGCAGAC AATAGACATT ATACTTTCTA TGTGTGGAAA 
AGAGTTTTTC AAAGATATGC AATTCTGAAA TATTTGTTAG TTCCAGCCTA TATATTTGCT 
GGTTGGAGTA TAGCTGACTC ATTGAAATCA AAGCCAATTT TTTGGAATTT AATGTTTTTC 
ATATGCTTGT TCATTGTTAT AGTTCCTCAG AAACTGCTGG AATTTCGTTA CTTCATTTTA 
CCTTATGTCA TTTATAGGCT TAACATAACT CTGCCTCCCA CATCCAGACT TGTTTGTGAA 
CTGAGTTGCT ATGCAATTGT TAATTTCATA ACTTTTTACA TCTTTCTGAA CAAGACTTTT 
CAGTGGCCAA ATAGTCAGGA CATTCAAAGG TTTATGTGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALG10B ( NM_001308340.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001295269.2 Homo sapiens ALG10 alpha-1,2-glucosyltransferase B (ALG10B), transcript variant 2, mRNA.

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CloneID	OHu108222
Clone ID Related Accession (Same CDS sequence)	NM_001308340.2
Accession Version	NM_001308340.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC117372.2. On May 31, 2019 this sequence version replaced NM_001308340.1. Transcript Variant: This variant (2) uses an alternate splice site in its 3' coding region, which results in a frameshift, compared to variant 1. It encodes isoform 2, which has a shorter and distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.78151.1, AL712776.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGCAGC TAGAGGGTTA CTGTTTCTCG GCCGCCTTGA GCTGTACCTT TTTAGTGTCC 
TGCCTCCTCT TCTCCGCCTT CAGCCGGGCG CTGCGAGAGC CCTACATGGA CGAGATCTTC 
CACCTGCCTC AGGCGCAGCG CTACTGTGAG GGCCATTTCT CCCTTTCCCA GTGGGATCCC 
ATGATTACTA CATTACCTGG CTTGTACCTG GTGTCAGTTG GAGTGGTCAA ACCTGCCATT 
TGGATCTTTG CATGGTCTGA ACATGTTGTC TGCTCCATTG GGATGCTCAG ATTTGTTAAT 
CTTCTCTTCA GTGTTGGCAA CTTCTATTTA CTATATTTGC TTTTCCACAA GGTACAACCC 
AGAAACAAGG AATACTTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001295269.2
CDS	121..501
Translation	MAQLEGYCFSAALSCTFLVSCLLFSAFSRALREPYMDEIFHLPQAQRYCEGHFSLSQWDPMITTLPGLYLVSVGVVKPAIWIFAWSEHVVCSIGMLRFVNLLFSVGNFYLLYLLFHKVQPRNKEYF

Target ORF information:

RefSeq Version	NM_001308340.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ALG10 alpha-1,2-glucosyltransferase B (ALG10B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001308340.2

ORF Insert Sequence:

ATGGCGCAGC TAGAGGGTTA CTGTTTCTCG GCCGCCTTGA GCTGTACCTT TTTAGTGTCC 
TGCCTCCTCT TCTCCGCCTT CAGCCGGGCG CTGCGAGAGC CCTACATGGA CGAGATCTTC 
CACCTGCCTC AGGCGCAGCG CTACTGTGAG GGCCATTTCT CCCTTTCCCA GTGGGATCCC 
ATGATTACTA CATTACCTGG CTTGTACCTG GTGTCAGTTG GAGTGGTCAA ACCTGCCATT 
TGGATCTTTG CATGGTCTGA ACATGTTGTC TGCTCCATTG GGATGCTCAG ATTTGTTAAT 
CTTCTCTTCA GTGTTGGCAA CTTCTATTTA CTATATTTGC TTTTCCACAA GGTACAACCC 
AGAAACAAGG AATACTTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A KCR1 variant implicated in susceptibility to the long QT syndrome.
Journal of molecular and cellular cardiology50(1)50-7(2011 Jan)
Hayashi K,Fujino N,Ino H,Uchiyama K,Sakata K,Konno T,Masuta E,Funada A,Sakamoto Y,Tsubokawa T,Hodatsu A,Yasuda T,Kanaya H,Kim MY,Kupershmidt S,Higashida H,Yamagishi M

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.
Nature genetics41(7)816-9(2009 Jul)
Daly AK,Donaldson PT,Bhatnagar P,Shen Y,Pe'er I,Floratos A,Daly MJ,Goldstein DB,John S,Nelson MR,Graham J,Park BK,Dillon JF,Bernal W,Cordell HJ,Pirmohamed M,Aithal GP,Day CP,,

In vivo identification of genes that modify ether-a-go-go-related gene activity in Caenorhabditis elegans may also affect human cardiac arrhythmia.
Proceedings of the National Academy of Sciences of the United States of America101(32)11773-8(2004 Aug)
Petersen CI,McFarland TR,Stepanovic SZ,Yang P,Reiner DJ,Hayashi K,George AL,Roden DM,Thomas JH,Balser JR

The IKr drug response is modulated by KCR1 in transfected cardiac and noncardiac cell lines.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology17(15)2263-5(2003 Dec)
Kupershmidt S,Yang IC,Hayashi K,Wei J,Chanthaphaychith S,Petersen CI,Johns DC,George AL Jr,Roden DM,Balser JR

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ALG10B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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