CPD cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CPD
Entrez Gene ID	1362
Full Name	carboxypeptidase D
Synonyms	GP180
General protein information	Preferred Names carboxypeptidase D Names carboxypeptidase D metallocarboxypeptidase D
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q11.2
Summary	The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	603102

mRNA and Protein(s)

mRNA	Protein	Name
NM_001304.4	NP_001295.2	carboxypeptidase D isoform 1 precursor
NM_001304.5	NP_001295.2	carboxypeptidase D isoform 1 precursor
NM_001199775.1	NP_001186704.1	carboxypeptidase D isoform 2

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Cpd	NP_036968.1
Drosophila melanogaster (fruit fly)	svr	NP_996319.1
Xenopus tropicalis (tropical clawed frog)	LOC101730225	XP_004912387.1
	LOC712407	XP_002808165.1
Canis lupus familiaris (dog)	CPD	XP_537756.2
Mus musculus (house mouse)	Cpd	NP_031780.2
Gallus gallus (chicken)	CPD	XP_004946700.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002414	XP_312538.5
Homo sapiens (human)	CPD	NP_001295.2
Pan troglodytes (chimpanzee)	CPD	XP_003315614.1
Danio rerio (zebrafish)	cpda	XP_691464.3
Caenorhabditis elegans (roundworm)	cpd-2	NP_510625.2

Gene Ontology
Bibliography

Related articles in PubMed

Prolactin/androgen-inducible carboxypeptidase-D increases with nitrotyrosine and Ki67 for breast cancer progression in vivo, and upregulates progression markers VEGF-C and Runx2 in vitro.
Thomas LN, Chedrawe ER, Barnes PJ, Too CKL
Breast cancer research and treatment164(1)27-40(2017 Jul)

microRNA-214 Governs Lung Cancer Growth and Metastasis by Targeting Carboxypeptidase-D.
Zhao X, Lu C, Chu W, Zhang Y, Zhang B, Zeng Q, Wang R, Li Z, Lv B, Liu J
DNA and cell biology35(11)715-721(2016 Nov)

Amyloid formation by human carboxypeptidase D transthyretin-like domain under physiological conditions.
Garcia-Pardo J, Gra?a-Montes R, Fernandez-Mendez M, Ruyra A, Roher N, Aviles FX, Lorenzo J, Ventura S
The Journal of biological chemistry289(49)33783-96(2014 Dec)

Carboxypeptidase-D is elevated in prostate cancer and its anti-apoptotic activity is abolished by combined androgen and prolactin receptor targeting.
Thomas LN, Merrimen J, Bell DG, Rendon R, Goffin V, Too CK
The Prostate74(7)732-42(2014 May)

Prolactin/Stat5 and androgen R1881 coactivate carboxypeptidase-D gene in breast cancer cells.
Koirala S, Thomas LN, Too CK
Molecular endocrinology (Baltimore, Md.)28(3)331-43(2014 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Carboxypeptidase-D (CPD) overexpression coincides with high-grade lung cancer and the CPD overexpression could reverse the inhibitory effects of miR-214
Title: microRNA-214 Governs Lung Cancer Growth and Metastasis by Targeting Carboxypeptidase-D.

The human carboxypeptidase D transthyretin-like domain forms amyloid under physiological conditions.
Title: Amyloid formation by human carboxypeptidase D transthyretin-like domain under physiological conditions.

CPD immunostaining and testosterone/prolactin-stimulated CPD expression were higher in prostate cancer than benign tissues/cells. Elevated CPD increased NO production, which was abolished when both androgen and prolactin receptors were inhibited.
Title: Carboxypeptidase-D is elevated in prostate cancer and its anti-apoptotic activity is abolished by combined androgen and prolactin receptor targeting.

Prolactin and R1881, acting through Stat5 and androgen receptor, act cooperatively to stimulate CPD gene transcription in breast cancer cells.
Title: Prolactin/Stat5 and androgen R1881 coactivate carboxypeptidase-D gene in breast cancer cells.

Carboxypeptidase D (CPD) is frequently upregulated in hepatocellular carcinoma; targeting CPD inhibits hepatocellular carcinoma cell proliferation through induction of G1 cell-cycle arrest and apoptosis.
Title: SiRNA-targeted carboxypeptidase D inhibits hepatocellular carcinoma growth.

The following CPD gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CPD cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu10876	NM_001304.5 Latest version!	Homo sapiens carboxypeptidase D (CPD), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu11492	NM_001199775.1 Latest version!	Homo sapiens carboxypeptidase D (CPD), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
View Old Accession Versions >>
OHu10876	NM_001304.4	Homo sapiens carboxypeptidase D (CPD), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CPD ( NM_001304.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001295.2 Homo sapiens carboxypeptidase D (CPD), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10876
Clone ID Related Accession (Same CDS sequence)	NM_001304.4 , NM_001304.5
Accession Version	NM_001304.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4143bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	carboxypeptidase D isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC090685.8, BC045624.1, AC006050.2 and CA436219.1. On Dec 17, 2010 this sequence version replaced NM_001304.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC051702.1, SRR1660809.117995.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGCG GCCGGGACGA GCGGCCGCCT TGGCGGCTAG GGCGGCTCCT GTTGCTCATG 
TGCCTGCTGC TGCTGGGGAG CTCGGCCCGG GCGGCTCACA TCAAGAAGGC GGAGGCGACT 
ACCACAACTA CGAGCGCGGG CGCCGAGGCG GCCGAGGGCC AGTTCGACCG CTACTACCAC 
GAAGAGGAGT TGGAGTCGGC GCTGAGGGAG GCGGCGGCCG CGGGCCTCCC CGGCCTGGCC 
CGCCTCTTTA GCATCGGCCG CTCGGTGGAA GGCCGGCCGC TGTGGGTGCT TCGCCTCACC 
GCCGGCCTGG GGTCGCTAAT CCCTGAGGGC GACGCGGGGC CTGACGCTGC CGGGCCCGAC 
GCTGCGGGGC CGCTGCTGCC CGGCCGGCCC CAGGTGAAGC TGGTGGGCAA CATGCATGGC 
GACGAGACCG TGTCGCGCCA GGTGTTGATC TACTTGGCCC GCGAGCTGGC GGCCGGCTAC 
CGCCGCGGGG ACCCGCGCCT GGTCCGCCTG CTCAACACCA CCGACGTGTA CCTGCTGCCC 
AGCCTCAACC CCGATGGCTT CGAGCGTGCC CGCGAGGGCG ACTGTGGCTT CGGCGACGGC 
GGCCCGTCCG GGGCCAGCGG CCGCGACAAT AGTCGCGGCC GCGACCTCAA CCGAAGCTTT 
CCCGACCAGT TTAGCACCGG CGAACCCCCC GCCCTGGACG AGGTGCCCGA GGTGCGCGCC 
CTCATCGAGT GGATCCGCAG GAACAAGTTT GTGCTTTCTG GAAATCTGCA TGGTGGCTCA 
GTGGTAGCAA GCTATCCTTT TGATGATTCT CCAGAACATA AGGCCACTGG AATCTATAGC 
AAAACCTCAG ATGATGAAGT ATTTAAATAC TTGGCAAAAG CTTATGCTTC AAACCACCCC 
ATAATGAAAA CTGGTGAGCC TCATTGTCCA GGAGATGAAG ACGAGACTTT CAAAGATGGA 
ATCACAAACG GCGCACATTG GTATGATGTG GAAGGTGGTA TGCAAGATTA CAATTATGTG 
TGGGCCAACT GTTTTGAGAT CACATTAGAA CTGTCTTGTT GCAAGTACCC ACCTGCTTCA 
CAGCTTCGAC AGGAATGGGA GAACAATCGT GAGTCTTTGA TCACATTGAT TGAAAAGGTT 
CACATTGGAG TGAAAGGATT TGTTAAAGAT TCCATAACAG GATCTGGGTT AGAGAATGCA 
ACCATCTCAG TGGCTGGTAT TAATCATAAT ATCACAACAG GCAGATTTGG TGATTTCTAC 
CGATTACTTG TTCCTGGAAC TTACAACCTT ACAGTAGTTT TAACTGGGTA TATGCCATTG 
ACTGTTACTA ATGTAGTGGT GAAAGAAGGA CCAGCCACAG AGGTGGATTT TTCTCTTAGG 
CCAACTGTAA CTTCAGTAAT CCCTGACACG ACAGAGGCTG TATCAACTGC TAGCACAGTT 
GCTATACCTA ATATTCTTTC TGGAACATCA TCCTCCTACC AGCCAATTCA GCCAAAGGAC 
TTTCACCACC ACCATTTCCC TGATATGGAA ATCTTCTTGA GAAGGTTTGC CAATGAATAT 
CCTAACATTA CCCGGCTTTA TTCCTTGGGA AAATCAGTAG AGTCAAGAGA ACTTTATGTG 
ATGGAGATAT CTGATAATCC GGGTGTCCAT GAACCAGGTG AACCAGAATT TAAGTACATT 
GGAAATATGC ATGGAAATGA AGTGGTTGGA AGAGAACTGC TGTTGAACCT CATAGAATAC 
CTTTGTAAGA ACTTTGGAAC AGACCCTGAA GTCACAGATT TGGTTCATAA CACTAGAATT 
CACCTTATGC CATCCATGAA TCCTGATGGG TATGAAAAGT CCCAGGAAGG AGATTCAATA 
AGTGTAATTG GCAGAAACAA CAGCAACAAC TTTGACCTGA ACCGAAATTT CCCAGACCAG 
TTTGTTCAGA TCACAGATCC TACGCAACCA GAAACTATTG CTGTAATGAG CTGGATGAAG 
TCCTATCCAT TTGTACTTTC AGCAAACCTG CATGGAGGTT CTTTGGTGGT TAACTACCCT 
TTTGATGATG ATGAACAAGG ACTTGCCACA TATAGTAAAT CACCAGATGA TGCTGTGTTC 
CAACAAATAG CACTTTCTTA TTCCAAGGAA AATTCCCAGA TGTTTCAAGG TAGACCTTGC 
AAGAATATGT ATCCTAATGA ATATTTTCCT CATGGAATAA CAAATGGAGC TAGTTGGTAT 
AATGTGCCAG GAGGAATGCA GGACTGGAAC TATTTACAAA CAAATTGCTT TGAAGTGACT 
ATTGAACTAG GTTGTGTGAA ATATCCACTT GAGAAAGAGC TGCCAAACTT TTGGGAACAG 
AATCGAAGAT CACTAATCCA GTTTATGAAA CAGGTTCATC AGGGCGTCAG AGGATTTGTT 
CTAGATGCCA CAGATGGCAG GGGTATATTA AATGCCACCA TTAGTGTTGC TGAGATTAAT 
CACCCAGTGA CTACTTACAA AACTGGAGAT TACTGGCGTC TCTTGGTTCC AGGAACTTAT 
AAAATCACAG CATCTGCTCG AGGGTATAAT CCAGTTACCA AGAATGTGAC TGTCAAGAGT 
GAAGGCGCTA TTCAGGTCAA CTTCACACTT GTTCGATCCT CAACAGATTC AAACAATGAA 
TCAAAGAAAG GAAAAGGGGC TAGCAGCAGC ACCAATGATG CCAGTGATCC AACTACTAAA 
GAGTTTGAAA CTTTAATTAA AGACCTTTCA GCGGAGAATG GTTTGGAAAG CCTCATGTTA 
CGCTCCTCCT CAAATCTGGC TCTGGCTCTT TATCGATACC ATTCCTACAA AGACTTATCA 
GAGTTTCTGA GAGGACTTGT AATGAACTAT CCACATATTA CAAATCTTAC CAATTTGGGA 
CAGAGCACTG AATATCGTCA CATTTGGTCC CTTGAAATCT CCAATAAGCC CAATGTATCT 
GAGCCTGAAG AACCAAAGAT TCGTTTTGTT GCTGGTATCC ATGGAAATGC GCCAGTTGGA 
ACTGAACTGC TTTTGGCTCT GGCAGAATTT CTCTGCCTGA ACTACAAAAA GAACCCAGCT 
GTTACCCAAT TGGTTGACAG GACTAGGATT GTGATTGTCC CTTCTCTAAA TCCAGATGGG 
CGAGAGAGAG CTCAAGAGAA AGACTGTACT TCAAAAATAG GACAAACAAA TGCTCGTGGC 
AAAGATTTGG ATACAGACTT CACAAATAAT GCCTCCCAAC CTGAGACCAA AGCCATCATT 
GAAAATTTGA TTCAAAAACA GGACTTTAGT CTTTCTGTTG CCTTAGATGG TGGTTCCATG 
CTGGTCACAT ATCCTTATGA CAAGCCAGTA CAGACAGTGG AAAATAAAGA GACTCTGAAG 
CATTTGGCAT CTCTTTATGC AAATAATCAT CCATCCATGC ACATGGGTCA GCCCAGTTGC 
CCAAATAAAT CAGATGAGAA TATTCCAGGA GGAGTAATGC GTGGAGCAGA ATGGCATAGT 
CACCTGGGCA GCATGAAGGA TTATAGTGTC ACCTATGGCC ATTGTCCGGA AATCACAGTA 
TACACAAGCT GCTGTTACTT TCCTAGTGCT GCACGACTCC CTTCCTTGTG GGCAGACAAT 
AAGAGATCTC TTCTTAGTAT GTTAGTGGAG GTTCACAAGG GAGTTCATGG ATTTGTTAAA 
GATAAGACTG GAAAGCCAAT CTCTAAAGCA GTCATTGTAC TTAATGAAGG AATAAAGGTA 
CAAACAAAAG AGGGAGGTTA TTTCCATGTA CTCTTAGCGC CAGGTGTCCA TAACATTATT 
GCCATCGCTG ATGGGTACCA GCAACAACAT TCACAGGTCT TTGTGCATCA TGATGCAGCT 
AGTTCTGTGG TGATAGTCTT TGACACAGAT AACCGGATAT TTGGTTTGCC AAGGGAGCTT 
GTGGTAACTG TATCAGGTGC TACTATGTCG GCATTGATCC TAACAGCTTG CATTATTTGG 
TGCATCTGCT CAATCAAGTC TAATAGACAC AAGGATGGCT TTCATCGGCT CAGGCAGCAT 
CATGATGAGT ATGAAGATGA AATTCGCATG ATGTCTACCG GCTCCAAGAA GTCCCTCCTA 
AGCCATGAGT TCCAGGATGA AACAGACACT GAAGAGGAAA CATTATATTC TAGCAAACAT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001295.2
CDS	58..4200
Translation	MASGRDERPPWRLGRLLLLMCLLLLGSSARAAHIKKAEATTTTTSAGAEAAEGQFDRYYHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPDAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEPPALDEVPEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEGGMQDYNYVWANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENATISVAGINHNITTGRFGDFYRLLVPGTYNLTVVLTGYMPLTVTNVVVKEGPATEVDFSLRPTVTSVIPDTTEAVSTASTVAIPNILSGTSSSYQPIQPKDFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSISVIGRNNSNNFDLNRNFPDQFVQITDPTQPETIAVMSWMKSYPFVLSANLHGGSLVVNYPFDDDEQGLATYSKSPDDAVFQQIALSYSKENSQMFQGRPCKNMYPNEYFPHGITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPLEKELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATDGRGILNATISVAEINHPVTTYKTGDYWRLLVPGTYKITASARGYNPVTKNVTVKSEGAIQVNFTLVRSSTDSNNESKKGKGASSSTNDASDPTTKEFETLIKDLSAENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNYKKNPAVTQLVDRTRIVIVPSLNPDGRERAQEKDCTSKIGQTNARGKDLDTDFTNNASQPETKAIIENLIQKQDFSLSVALDGGSMLVTYPYDKPVQTVENKETLKHLASLYANNHPSMHMGQPSCPNKSDENIPGGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSCCYFPSAARLPSLWADNKRSLLSMLVEVHKGVHGFVKDKTGKPISKAVIVLNEGIKVQTKEGGYFHVLLAPGVHNIIAIADGYQQQHSQVFVHHDAASSVVIVFDTDNRIFGLPRELVVTVSGATMSALILTACIIWCICSIKSNRHKDGFHRLRQHHDEYEDEIRMMSTGSKKSLLSHEFQDETDTEEETLYSSKH

Target ORF information:

RefSeq Version	NM_001304.4
Organism	Homo sapiens(human)
Definition	Homo sapiens carboxypeptidase D (CPD), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001304.4

ORF Insert Sequence:

ATGGCGAGCG GCCGGGACGA GCGGCCGCCT TGGCGGCTAG GGCGGCTCCT GTTGCTCATG 
TGCCTGCTGC TGCTGGGGAG CTCGGCCCGG GCGGCTCACA TCAAGAAGGC GGAGGCGACT 
ACCACAACTA CGAGCGCGGG CGCCGAGGCG GCCGAGGGCC AGTTCGACCG CTACTACCAC 
GAAGAGGAGT TGGAGTCGGC GCTGAGGGAG GCGGCGGCCG CGGGCCTCCC CGGCCTGGCC 
CGCCTCTTTA GCATCGGCCG CTCGGTGGAA GGCCGGCCGC TGTGGGTGCT TCGCCTCACC 
GCCGGCCTGG GGTCGCTAAT CCCTGAGGGC GACGCGGGGC CTGACGCTGC CGGGCCCGAC 
GCTGCGGGGC CGCTGCTGCC CGGCCGGCCC CAGGTGAAGC TGGTGGGCAA CATGCATGGC 
GACGAGACCG TGTCGCGCCA GGTGTTGATC TACTTGGCCC GCGAGCTGGC GGCCGGCTAC 
CGCCGCGGGG ACCCGCGCCT GGTCCGCCTG CTCAACACCA CCGACGTGTA CCTGCTGCCC 
AGCCTCAACC CCGATGGCTT CGAGCGTGCC CGCGAGGGCG ACTGTGGCTT CGGCGACGGC 
GGCCCGTCCG GGGCCAGCGG CCGCGACAAT AGTCGCGGCC GCGACCTCAA CCGAAGCTTT 
CCCGACCAGT TTAGCACCGG CGAACCCCCC GCCCTGGACG AGGTGCCCGA GGTGCGCGCC 
CTCATCGAGT GGATCCGCAG GAACAAGTTT GTGCTTTCTG GAAATCTGCA TGGTGGCTCA 
GTGGTAGCAA GCTATCCTTT TGATGATTCT CCAGAACATA AGGCCACTGG AATCTATAGC 
AAAACCTCAG ATGATGAAGT ATTTAAATAC TTGGCAAAAG CTTATGCTTC AAACCACCCC 
ATAATGAAAA CTGGTGAGCC TCATTGTCCA GGAGATGAAG ACGAGACTTT CAAAGATGGA 
ATCACAAACG GCGCACATTG GTATGATGTG GAAGGTGGTA TGCAAGATTA CAATTATGTG 
TGGGCCAACT GTTTTGAGAT CACATTAGAA CTGTCTTGTT GCAAGTACCC ACCTGCTTCA 
CAGCTTCGAC AGGAATGGGA GAACAATCGT GAGTCTTTGA TCACATTGAT TGAAAAGGTT 
CACATTGGAG TGAAAGGATT TGTTAAAGAT TCCATAACAG GATCTGGGTT AGAGAATGCA 
ACCATCTCAG TGGCTGGTAT TAATCATAAT ATCACAACAG GCAGATTTGG TGATTTCTAC 
CGATTACTTG TTCCTGGAAC TTACAACCTT ACAGTAGTTT TAACTGGGTA TATGCCATTG 
ACTGTTACTA ATGTAGTGGT GAAAGAAGGA CCAGCCACAG AGGTGGATTT TTCTCTTAGG 
CCAACTGTAA CTTCAGTAAT CCCTGACACG ACAGAGGCTG TATCAACTGC TAGCACAGTT 
GCTATACCTA ATATTCTTTC TGGAACATCA TCCTCCTACC AGCCAATTCA GCCAAAGGAC 
TTTCACCACC ACCATTTCCC TGATATGGAA ATCTTCTTGA GAAGGTTTGC CAATGAATAT 
CCTAACATTA CCCGGCTTTA TTCCTTGGGA AAATCAGTAG AGTCAAGAGA ACTTTATGTG 
ATGGAGATAT CTGATAATCC GGGTGTCCAT GAACCAGGTG AACCAGAATT TAAGTACATT 
GGAAATATGC ATGGAAATGA AGTGGTTGGA AGAGAACTGC TGTTGAACCT CATAGAATAC 
CTTTGTAAGA ACTTTGGAAC AGACCCTGAA GTCACAGATT TGGTTCATAA CACTAGAATT 
CACCTTATGC CATCCATGAA TCCTGATGGG TATGAAAAGT CCCAGGAAGG AGATTCAATA 
AGTGTAATTG GCAGAAACAA CAGCAACAAC TTTGACCTGA ACCGAAATTT CCCAGACCAG 
TTTGTTCAGA TCACAGATCC TACGCAACCA GAAACTATTG CTGTAATGAG CTGGATGAAG 
TCCTATCCAT TTGTACTTTC AGCAAACCTG CATGGAGGTT CTTTGGTGGT TAACTACCCT 
TTTGATGATG ATGAACAAGG ACTTGCCACA TATAGTAAAT CACCAGATGA TGCTGTGTTC 
CAACAAATAG CACTTTCTTA TTCCAAGGAA AATTCCCAGA TGTTTCAAGG TAGACCTTGC 
AAGAATATGT ATCCTAATGA ATATTTTCCT CATGGAATAA CAAATGGAGC TAGTTGGTAT 
AATGTGCCAG GAGGAATGCA GGACTGGAAC TATTTACAAA CAAATTGCTT TGAAGTGACT 
ATTGAACTAG GTTGTGTGAA ATATCCACTT GAGAAAGAGC TGCCAAACTT TTGGGAACAG 
AATCGAAGAT CACTAATCCA GTTTATGAAA CAGGTTCATC AGGGCGTCAG AGGATTTGTT 
CTAGATGCCA CAGATGGCAG GGGTATATTA AATGCCACCA TTAGTGTTGC TGAGATTAAT 
CACCCAGTGA CTACTTACAA AACTGGAGAT TACTGGCGTC TCTTGGTTCC AGGAACTTAT 
AAAATCACAG CATCTGCTCG AGGGTATAAT CCAGTTACCA AGAATGTGAC TGTCAAGAGT 
GAAGGCGCTA TTCAGGTCAA CTTCACACTT GTTCGATCCT CAACAGATTC AAACAATGAA 
TCAAAGAAAG GAAAAGGGGC TAGCAGCAGC ACCAATGATG CCAGTGATCC AACTACTAAA 
GAGTTTGAAA CTTTAATTAA AGACCTTTCA GCGGAGAATG GTTTGGAAAG CCTCATGTTA 
CGCTCCTCCT CAAATCTGGC TCTGGCTCTT TATCGATACC ATTCCTACAA AGACTTATCA 
GAGTTTCTGA GAGGACTTGT AATGAACTAT CCACATATTA CAAATCTTAC CAATTTGGGA 
CAGAGCACTG AATATCGTCA CATTTGGTCC CTTGAAATCT CCAATAAGCC CAATGTATCT 
GAGCCTGAAG AACCAAAGAT TCGTTTTGTT GCTGGTATCC ATGGAAATGC GCCAGTTGGA 
ACTGAACTGC TTTTGGCTCT GGCAGAATTT CTCTGCCTGA ACTACAAAAA GAACCCAGCT 
GTTACCCAAT TGGTTGACAG GACTAGGATT GTGATTGTCC CTTCTCTAAA TCCAGATGGG 
CGAGAGAGAG CTCAAGAGAA AGACTGTACT TCAAAAATAG GACAAACAAA TGCTCGTGGC 
AAAGATTTGG ATACAGACTT CACAAATAAT GCCTCCCAAC CTGAGACCAA AGCCATCATT 
GAAAATTTGA TTCAAAAACA GGACTTTAGT CTTTCTGTTG CCTTAGATGG TGGTTCCATG 
CTGGTCACAT ATCCTTATGA CAAGCCAGTA CAGACAGTGG AAAATAAAGA GACTCTGAAG 
CATTTGGCAT CTCTTTATGC AAATAATCAT CCATCCATGC ACATGGGTCA GCCCAGTTGC 
CCAAATAAAT CAGATGAGAA TATTCCAGGA GGAGTAATGC GTGGAGCAGA ATGGCATAGT 
CACCTGGGCA GCATGAAGGA TTATAGTGTC ACCTATGGCC ATTGTCCGGA AATCACAGTA 
TACACAAGCT GCTGTTACTT TCCTAGTGCT GCACGACTCC CTTCCTTGTG GGCAGACAAT 
AAGAGATCTC TTCTTAGTAT GTTAGTGGAG GTTCACAAGG GAGTTCATGG ATTTGTTAAA 
GATAAGACTG GAAAGCCAAT CTCTAAAGCA GTCATTGTAC TTAATGAAGG AATAAAGGTA 
CAAACAAAAG AGGGAGGTTA TTTCCATGTA CTCTTAGCGC CAGGTGTCCA TAACATTATT 
GCCATCGCTG ATGGGTACCA GCAACAACAT TCACAGGTCT TTGTGCATCA TGATGCAGCT 
AGTTCTGTGG TGATAGTCTT TGACACAGAT AACCGGATAT TTGGTTTGCC AAGGGAGCTT 
GTGGTAACTG TATCAGGTGC TACTATGTCG GCATTGATCC TAACAGCTTG CATTATTTGG 
TGCATCTGCT CAATCAAGTC TAATAGACAC AAGGATGGCT TTCATCGGCT CAGGCAGCAT 
CATGATGAGT ATGAAGATGA AATTCGCATG ATGTCTACCG GCTCCAAGAA GTCCCTCCTA 
AGCCATGAGT TCCAGGATGA AACAGACACT GAAGAGGAAA CATTATATTC TAGCAAACAT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CPD ( NM_001304.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001295.2 Homo sapiens carboxypeptidase D (CPD), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10876
Clone ID Related Accession (Same CDS sequence)	NM_001304.4 , NM_001304.5
Accession Version	NM_001304.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4143bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	carboxypeptidase D isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC090685.8, BC045624.1, AC006050.2 and CA436219.1. On Nov 23, 2018 this sequence version replaced NM_001304.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.253032.1, SRR1660809.117995.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000225719.9/ ENSP00000225719.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGAGCG GCCGGGACGA GCGGCCGCCT TGGCGGCTAG GGCGGCTCCT GTTGCTCATG 
TGCCTGCTGC TGCTGGGGAG CTCGGCCCGG GCGGCTCACA TCAAGAAGGC GGAGGCGACT 
ACCACAACTA CGAGCGCGGG CGCCGAGGCG GCCGAGGGCC AGTTCGACCG CTACTACCAC 
GAAGAGGAGT TGGAGTCGGC GCTGAGGGAG GCGGCGGCCG CGGGCCTCCC CGGCCTGGCC 
CGCCTCTTTA GCATCGGCCG CTCGGTGGAA GGCCGGCCGC TGTGGGTGCT TCGCCTCACC 
GCCGGCCTGG GGTCGCTAAT CCCTGAGGGC GACGCGGGGC CTGACGCTGC CGGGCCCGAC 
GCTGCGGGGC CGCTGCTGCC CGGCCGGCCC CAGGTGAAGC TGGTGGGCAA CATGCATGGC 
GACGAGACCG TGTCGCGCCA GGTGTTGATC TACTTGGCCC GCGAGCTGGC GGCCGGCTAC 
CGCCGCGGGG ACCCGCGCCT GGTCCGCCTG CTCAACACCA CCGACGTGTA CCTGCTGCCC 
AGCCTCAACC CCGATGGCTT CGAGCGTGCC CGCGAGGGCG ACTGTGGCTT CGGCGACGGC 
GGCCCGTCCG GGGCCAGCGG CCGCGACAAT AGTCGCGGCC GCGACCTCAA CCGAAGCTTT 
CCCGACCAGT TTAGCACCGG CGAACCCCCC GCCCTGGACG AGGTGCCCGA GGTGCGCGCC 
CTCATCGAGT GGATCCGCAG GAACAAGTTT GTGCTTTCTG GAAATCTGCA TGGTGGCTCA 
GTGGTAGCAA GCTATCCTTT TGATGATTCT CCAGAACATA AGGCCACTGG AATCTATAGC 
AAAACCTCAG ATGATGAAGT ATTTAAATAC TTGGCAAAAG CTTATGCTTC AAACCACCCC 
ATAATGAAAA CTGGTGAGCC TCATTGTCCA GGAGATGAAG ACGAGACTTT CAAAGATGGA 
ATCACAAACG GCGCACATTG GTATGATGTG GAAGGTGGTA TGCAAGATTA CAATTATGTG 
TGGGCCAACT GTTTTGAGAT CACATTAGAA CTGTCTTGTT GCAAGTACCC ACCTGCTTCA 
CAGCTTCGAC AGGAATGGGA GAACAATCGT GAGTCTTTGA TCACATTGAT TGAAAAGGTT 
CACATTGGAG TGAAAGGATT TGTTAAAGAT TCCATAACAG GATCTGGGTT AGAGAATGCA 
ACCATCTCAG TGGCTGGTAT TAATCATAAT ATCACAACAG GCAGATTTGG TGATTTCTAC 
CGATTACTTG TTCCTGGAAC TTACAACCTT ACAGTAGTTT TAACTGGGTA TATGCCATTG 
ACTGTTACTA ATGTAGTGGT GAAAGAAGGA CCAGCCACAG AGGTGGATTT TTCTCTTAGG 
CCAACTGTAA CTTCAGTAAT CCCTGACACG ACAGAGGCTG TATCAACTGC TAGCACAGTT 
GCTATACCTA ATATTCTTTC TGGAACATCA TCCTCCTACC AGCCAATTCA GCCAAAGGAC 
TTTCACCACC ACCATTTCCC TGATATGGAA ATCTTCTTGA GAAGGTTTGC CAATGAATAT 
CCTAACATTA CCCGGCTTTA TTCCTTGGGA AAATCAGTAG AGTCAAGAGA ACTTTATGTG 
ATGGAGATAT CTGATAATCC GGGTGTCCAT GAACCAGGTG AACCAGAATT TAAGTACATT 
GGAAATATGC ATGGAAATGA AGTGGTTGGA AGAGAACTGC TGTTGAACCT CATAGAATAC 
CTTTGTAAGA ACTTTGGAAC AGACCCTGAA GTCACAGATT TGGTTCATAA CACTAGAATT 
CACCTTATGC CATCCATGAA TCCTGATGGG TATGAAAAGT CCCAGGAAGG AGATTCAATA 
AGTGTAATTG GCAGAAACAA CAGCAACAAC TTTGACCTGA ACCGAAATTT CCCAGACCAG 
TTTGTTCAGA TCACAGATCC TACGCAACCA GAAACTATTG CTGTAATGAG CTGGATGAAG 
TCCTATCCAT TTGTACTTTC AGCAAACCTG CATGGAGGTT CTTTGGTGGT TAACTACCCT 
TTTGATGATG ATGAACAAGG ACTTGCCACA TATAGTAAAT CACCAGATGA TGCTGTGTTC 
CAACAAATAG CACTTTCTTA TTCCAAGGAA AATTCCCAGA TGTTTCAAGG TAGACCTTGC 
AAGAATATGT ATCCTAATGA ATATTTTCCT CATGGAATAA CAAATGGAGC TAGTTGGTAT 
AATGTGCCAG GAGGAATGCA GGACTGGAAC TATTTACAAA CAAATTGCTT TGAAGTGACT 
ATTGAACTAG GTTGTGTGAA ATATCCACTT GAGAAAGAGC TGCCAAACTT TTGGGAACAG 
AATCGAAGAT CACTAATCCA GTTTATGAAA CAGGTTCATC AGGGCGTCAG AGGATTTGTT 
CTAGATGCCA CAGATGGCAG GGGTATATTA AATGCCACCA TTAGTGTTGC TGAGATTAAT 
CACCCAGTGA CTACTTACAA AACTGGAGAT TACTGGCGTC TCTTGGTTCC AGGAACTTAT 
AAAATCACAG CATCTGCTCG AGGGTATAAT CCAGTTACCA AGAATGTGAC TGTCAAGAGT 
GAAGGCGCTA TTCAGGTCAA CTTCACACTT GTTCGATCCT CAACAGATTC AAACAATGAA 
TCAAAGAAAG GAAAAGGGGC TAGCAGCAGC ACCAATGATG CCAGTGATCC AACTACTAAA 
GAGTTTGAAA CTTTAATTAA AGACCTTTCA GCGGAGAATG GTTTGGAAAG CCTCATGTTA 
CGCTCCTCCT CAAATCTGGC TCTGGCTCTT TATCGATACC ATTCCTACAA AGACTTATCA 
GAGTTTCTGA GAGGACTTGT AATGAACTAT CCACATATTA CAAATCTTAC CAATTTGGGA 
CAGAGCACTG AATATCGTCA CATTTGGTCC CTTGAAATCT CCAATAAGCC CAATGTATCT 
GAGCCTGAAG AACCAAAGAT TCGTTTTGTT GCTGGTATCC ATGGAAATGC GCCAGTTGGA 
ACTGAACTGC TTTTGGCTCT GGCAGAATTT CTCTGCCTGA ACTACAAAAA GAACCCAGCT 
GTTACCCAAT TGGTTGACAG GACTAGGATT GTGATTGTCC CTTCTCTAAA TCCAGATGGG 
CGAGAGAGAG CTCAAGAGAA AGACTGTACT TCAAAAATAG GACAAACAAA TGCTCGTGGC 
AAAGATTTGG ATACAGACTT CACAAATAAT GCCTCCCAAC CTGAGACCAA AGCCATCATT 
GAAAATTTGA TTCAAAAACA GGACTTTAGT CTTTCTGTTG CCTTAGATGG TGGTTCCATG 
CTGGTCACAT ATCCTTATGA CAAGCCAGTA CAGACAGTGG AAAATAAAGA GACTCTGAAG 
CATTTGGCAT CTCTTTATGC AAATAATCAT CCATCCATGC ACATGGGTCA GCCCAGTTGC 
CCAAATAAAT CAGATGAGAA TATTCCAGGA GGAGTAATGC GTGGAGCAGA ATGGCATAGT 
CACCTGGGCA GCATGAAGGA TTATAGTGTC ACCTATGGCC ATTGTCCGGA AATCACAGTA 
TACACAAGCT GCTGTTACTT TCCTAGTGCT GCACGACTCC CTTCCTTGTG GGCAGACAAT 
AAGAGATCTC TTCTTAGTAT GTTAGTGGAG GTTCACAAGG GAGTTCATGG ATTTGTTAAA 
GATAAGACTG GAAAGCCAAT CTCTAAAGCA GTCATTGTAC TTAATGAAGG AATAAAGGTA 
CAAACAAAAG AGGGAGGTTA TTTCCATGTA CTCTTAGCGC CAGGTGTCCA TAACATTATT 
GCCATCGCTG ATGGGTACCA GCAACAACAT TCACAGGTCT TTGTGCATCA TGATGCAGCT 
AGTTCTGTGG TGATAGTCTT TGACACAGAT AACCGGATAT TTGGTTTGCC AAGGGAGCTT 
GTGGTAACTG TATCAGGTGC TACTATGTCG GCATTGATCC TAACAGCTTG CATTATTTGG 
TGCATCTGCT CAATCAAGTC TAATAGACAC AAGGATGGCT TTCATCGGCT CAGGCAGCAT 
CATGATGAGT ATGAAGATGA AATTCGCATG ATGTCTACCG GCTCCAAGAA GTCCCTCCTA 
AGCCATGAGT TCCAGGATGA AACAGACACT GAAGAGGAAA CATTATATTC TAGCAAACAT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001295.2
CDS	55..4197
Translation	MASGRDERPPWRLGRLLLLMCLLLLGSSARAAHIKKAEATTTTTSAGAEAAEGQFDRYYHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPDAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEPPALDEVPEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEGGMQDYNYVWANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENATISVAGINHNITTGRFGDFYRLLVPGTYNLTVVLTGYMPLTVTNVVVKEGPATEVDFSLRPTVTSVIPDTTEAVSTASTVAIPNILSGTSSSYQPIQPKDFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSISVIGRNNSNNFDLNRNFPDQFVQITDPTQPETIAVMSWMKSYPFVLSANLHGGSLVVNYPFDDDEQGLATYSKSPDDAVFQQIALSYSKENSQMFQGRPCKNMYPNEYFPHGITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPLEKELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATDGRGILNATISVAEINHPVTTYKTGDYWRLLVPGTYKITASARGYNPVTKNVTVKSEGAIQVNFTLVRSSTDSNNESKKGKGASSSTNDASDPTTKEFETLIKDLSAENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNYKKNPAVTQLVDRTRIVIVPSLNPDGRERAQEKDCTSKIGQTNARGKDLDTDFTNNASQPETKAIIENLIQKQDFSLSVALDGGSMLVTYPYDKPVQTVENKETLKHLASLYANNHPSMHMGQPSCPNKSDENIPGGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSCCYFPSAARLPSLWADNKRSLLSMLVEVHKGVHGFVKDKTGKPISKAVIVLNEGIKVQTKEGGYFHVLLAPGVHNIIAIADGYQQQHSQVFVHHDAASSVVIVFDTDNRIFGLPRELVVTVSGATMSALILTACIIWCICSIKSNRHKDGFHRLRQHHDEYEDEIRMMSTGSKKSLLSHEFQDETDTEEETLYSSKH

Target ORF information:

RefSeq Version	NM_001304.5
Organism	Homo sapiens(human)
Definition	Homo sapiens carboxypeptidase D (CPD), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001304.5

ORF Insert Sequence:

ATGGCGAGCG GCCGGGACGA GCGGCCGCCT TGGCGGCTAG GGCGGCTCCT GTTGCTCATG 
TGCCTGCTGC TGCTGGGGAG CTCGGCCCGG GCGGCTCACA TCAAGAAGGC GGAGGCGACT 
ACCACAACTA CGAGCGCGGG CGCCGAGGCG GCCGAGGGCC AGTTCGACCG CTACTACCAC 
GAAGAGGAGT TGGAGTCGGC GCTGAGGGAG GCGGCGGCCG CGGGCCTCCC CGGCCTGGCC 
CGCCTCTTTA GCATCGGCCG CTCGGTGGAA GGCCGGCCGC TGTGGGTGCT TCGCCTCACC 
GCCGGCCTGG GGTCGCTAAT CCCTGAGGGC GACGCGGGGC CTGACGCTGC CGGGCCCGAC 
GCTGCGGGGC CGCTGCTGCC CGGCCGGCCC CAGGTGAAGC TGGTGGGCAA CATGCATGGC 
GACGAGACCG TGTCGCGCCA GGTGTTGATC TACTTGGCCC GCGAGCTGGC GGCCGGCTAC 
CGCCGCGGGG ACCCGCGCCT GGTCCGCCTG CTCAACACCA CCGACGTGTA CCTGCTGCCC 
AGCCTCAACC CCGATGGCTT CGAGCGTGCC CGCGAGGGCG ACTGTGGCTT CGGCGACGGC 
GGCCCGTCCG GGGCCAGCGG CCGCGACAAT AGTCGCGGCC GCGACCTCAA CCGAAGCTTT 
CCCGACCAGT TTAGCACCGG CGAACCCCCC GCCCTGGACG AGGTGCCCGA GGTGCGCGCC 
CTCATCGAGT GGATCCGCAG GAACAAGTTT GTGCTTTCTG GAAATCTGCA TGGTGGCTCA 
GTGGTAGCAA GCTATCCTTT TGATGATTCT CCAGAACATA AGGCCACTGG AATCTATAGC 
AAAACCTCAG ATGATGAAGT ATTTAAATAC TTGGCAAAAG CTTATGCTTC AAACCACCCC 
ATAATGAAAA CTGGTGAGCC TCATTGTCCA GGAGATGAAG ACGAGACTTT CAAAGATGGA 
ATCACAAACG GCGCACATTG GTATGATGTG GAAGGTGGTA TGCAAGATTA CAATTATGTG 
TGGGCCAACT GTTTTGAGAT CACATTAGAA CTGTCTTGTT GCAAGTACCC ACCTGCTTCA 
CAGCTTCGAC AGGAATGGGA GAACAATCGT GAGTCTTTGA TCACATTGAT TGAAAAGGTT 
CACATTGGAG TGAAAGGATT TGTTAAAGAT TCCATAACAG GATCTGGGTT AGAGAATGCA 
ACCATCTCAG TGGCTGGTAT TAATCATAAT ATCACAACAG GCAGATTTGG TGATTTCTAC 
CGATTACTTG TTCCTGGAAC TTACAACCTT ACAGTAGTTT TAACTGGGTA TATGCCATTG 
ACTGTTACTA ATGTAGTGGT GAAAGAAGGA CCAGCCACAG AGGTGGATTT TTCTCTTAGG 
CCAACTGTAA CTTCAGTAAT CCCTGACACG ACAGAGGCTG TATCAACTGC TAGCACAGTT 
GCTATACCTA ATATTCTTTC TGGAACATCA TCCTCCTACC AGCCAATTCA GCCAAAGGAC 
TTTCACCACC ACCATTTCCC TGATATGGAA ATCTTCTTGA GAAGGTTTGC CAATGAATAT 
CCTAACATTA CCCGGCTTTA TTCCTTGGGA AAATCAGTAG AGTCAAGAGA ACTTTATGTG 
ATGGAGATAT CTGATAATCC GGGTGTCCAT GAACCAGGTG AACCAGAATT TAAGTACATT 
GGAAATATGC ATGGAAATGA AGTGGTTGGA AGAGAACTGC TGTTGAACCT CATAGAATAC 
CTTTGTAAGA ACTTTGGAAC AGACCCTGAA GTCACAGATT TGGTTCATAA CACTAGAATT 
CACCTTATGC CATCCATGAA TCCTGATGGG TATGAAAAGT CCCAGGAAGG AGATTCAATA 
AGTGTAATTG GCAGAAACAA CAGCAACAAC TTTGACCTGA ACCGAAATTT CCCAGACCAG 
TTTGTTCAGA TCACAGATCC TACGCAACCA GAAACTATTG CTGTAATGAG CTGGATGAAG 
TCCTATCCAT TTGTACTTTC AGCAAACCTG CATGGAGGTT CTTTGGTGGT TAACTACCCT 
TTTGATGATG ATGAACAAGG ACTTGCCACA TATAGTAAAT CACCAGATGA TGCTGTGTTC 
CAACAAATAG CACTTTCTTA TTCCAAGGAA AATTCCCAGA TGTTTCAAGG TAGACCTTGC 
AAGAATATGT ATCCTAATGA ATATTTTCCT CATGGAATAA CAAATGGAGC TAGTTGGTAT 
AATGTGCCAG GAGGAATGCA GGACTGGAAC TATTTACAAA CAAATTGCTT TGAAGTGACT 
ATTGAACTAG GTTGTGTGAA ATATCCACTT GAGAAAGAGC TGCCAAACTT TTGGGAACAG 
AATCGAAGAT CACTAATCCA GTTTATGAAA CAGGTTCATC AGGGCGTCAG AGGATTTGTT 
CTAGATGCCA CAGATGGCAG GGGTATATTA AATGCCACCA TTAGTGTTGC TGAGATTAAT 
CACCCAGTGA CTACTTACAA AACTGGAGAT TACTGGCGTC TCTTGGTTCC AGGAACTTAT 
AAAATCACAG CATCTGCTCG AGGGTATAAT CCAGTTACCA AGAATGTGAC TGTCAAGAGT 
GAAGGCGCTA TTCAGGTCAA CTTCACACTT GTTCGATCCT CAACAGATTC AAACAATGAA 
TCAAAGAAAG GAAAAGGGGC TAGCAGCAGC ACCAATGATG CCAGTGATCC AACTACTAAA 
GAGTTTGAAA CTTTAATTAA AGACCTTTCA GCGGAGAATG GTTTGGAAAG CCTCATGTTA 
CGCTCCTCCT CAAATCTGGC TCTGGCTCTT TATCGATACC ATTCCTACAA AGACTTATCA 
GAGTTTCTGA GAGGACTTGT AATGAACTAT CCACATATTA CAAATCTTAC CAATTTGGGA 
CAGAGCACTG AATATCGTCA CATTTGGTCC CTTGAAATCT CCAATAAGCC CAATGTATCT 
GAGCCTGAAG AACCAAAGAT TCGTTTTGTT GCTGGTATCC ATGGAAATGC GCCAGTTGGA 
ACTGAACTGC TTTTGGCTCT GGCAGAATTT CTCTGCCTGA ACTACAAAAA GAACCCAGCT 
GTTACCCAAT TGGTTGACAG GACTAGGATT GTGATTGTCC CTTCTCTAAA TCCAGATGGG 
CGAGAGAGAG CTCAAGAGAA AGACTGTACT TCAAAAATAG GACAAACAAA TGCTCGTGGC 
AAAGATTTGG ATACAGACTT CACAAATAAT GCCTCCCAAC CTGAGACCAA AGCCATCATT 
GAAAATTTGA TTCAAAAACA GGACTTTAGT CTTTCTGTTG CCTTAGATGG TGGTTCCATG 
CTGGTCACAT ATCCTTATGA CAAGCCAGTA CAGACAGTGG AAAATAAAGA GACTCTGAAG 
CATTTGGCAT CTCTTTATGC AAATAATCAT CCATCCATGC ACATGGGTCA GCCCAGTTGC 
CCAAATAAAT CAGATGAGAA TATTCCAGGA GGAGTAATGC GTGGAGCAGA ATGGCATAGT 
CACCTGGGCA GCATGAAGGA TTATAGTGTC ACCTATGGCC ATTGTCCGGA AATCACAGTA 
TACACAAGCT GCTGTTACTT TCCTAGTGCT GCACGACTCC CTTCCTTGTG GGCAGACAAT 
AAGAGATCTC TTCTTAGTAT GTTAGTGGAG GTTCACAAGG GAGTTCATGG ATTTGTTAAA 
GATAAGACTG GAAAGCCAAT CTCTAAAGCA GTCATTGTAC TTAATGAAGG AATAAAGGTA 
CAAACAAAAG AGGGAGGTTA TTTCCATGTA CTCTTAGCGC CAGGTGTCCA TAACATTATT 
GCCATCGCTG ATGGGTACCA GCAACAACAT TCACAGGTCT TTGTGCATCA TGATGCAGCT 
AGTTCTGTGG TGATAGTCTT TGACACAGAT AACCGGATAT TTGGTTTGCC AAGGGAGCTT 
GTGGTAACTG TATCAGGTGC TACTATGTCG GCATTGATCC TAACAGCTTG CATTATTTGG 
TGCATCTGCT CAATCAAGTC TAATAGACAC AAGGATGGCT TTCATCGGCT CAGGCAGCAT 
CATGATGAGT ATGAAGATGA AATTCGCATG ATGTCTACCG GCTCCAAGAA GTCCCTCCTA 
AGCCATGAGT TCCAGGATGA AACAGACACT GAAGAGGAAA CATTATATTC TAGCAAACAT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CPD ( NM_001199775.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186704.1 Homo sapiens carboxypeptidase D (CPD), transcript variant 2, mRNA.

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CloneID	OHu11492
Clone ID Related Accession (Same CDS sequence)	NM_001199775.1
Accession Version	NM_001199775.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3402bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-01
Organism	Homo sapiens(human)
Product	carboxypeptidase D isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK316409.1, AC006050.2 and CA436219.1. Transcript Variant: This variant (2) differs in the 5' UTR and coding region and uses an alternate start codon compared to variant 1. The resulting protein (isoform 2) is shorter and has a distinct N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK316409.1, AK302497.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGTTTG TGCTTTCTGG AAATCTGCAT GGTGGCTCAG TGGTAGCAAG CTATCCTTTT 
GATGATTCTC CAGAACATAA GGCCACTGGA ATCTATAGCA AAACCTCAGA TGATGAAGTA 
TTTAAATACT TGGCAAAAGC TTATGCTTCA AACCACCCCA TAATGAAAAC TGGTGAGCCT 
CATTGTCCAG GAGATGAAGA CGAGACTTTC AAAGATGGAA TCACAAACGG CGCACATTGG 
TATGATGTGG AAGGTGGTAT GCAAGATTAC AATTATGTGT GGGCCAACTG TTTTGAGATC 
ACATTAGAAC TGTCTTGTTG CAAGTACCCA CCTGCTTCAC AGCTTCGACA GGAATGGGAG 
AACAATCGTG AGTCTTTGAT CACATTGATT GAAAAGGTTC ACATTGGAGT GAAAGGATTT 
GTTAAAGATT CCATAACAGG ATCTGGGTTA GAGAATGCAA CCATCTCAGT GGCTGGTATT 
AATCATAATA TCACAACAGG CAGATTTGGT GATTTCTACC GATTACTTGT TCCTGGAACT 
TACAACCTTA CAGTAGTTTT AACTGGGTAT ATGCCATTGA CTGTTACTAA TGTAGTGGTG 
AAAGAAGGAC CAGCCACAGA GGTGGATTTT TCTCTTAGGC CAACTGTAAC TTCAGTAATC 
CCTGACACGA CAGAGGCTGT ATCAACTGCT AGCACAGTTG CTATACCTAA TATTCTTTCT 
GGAACATCAT CCTCCTACCA GCCAATTCAG CCAAAGGACT TTCACCACCA CCATTTCCCT 
GATATGGAAA TCTTCTTGAG AAGGTTTGCC AATGAATATC CTAACATTAC CCGGCTTTAT 
TCCTTGGGAA AATCAGTAGA GTCAAGAGAA CTTTATGTGA TGGAGATATC TGATAATCCG 
GGTGTCCATG AACCAGGTGA ACCAGAATTT AAGTACATTG GAAATATGCA TGGAAATGAA 
GTGGTTGGAA GAGAACTGCT GTTGAACCTC ATAGAATACC TTTGTAAGAA CTTTGGAACA 
GACCCTGAAG TCACAGATTT GGTTCATAAC ACTAGAATTC ACCTTATGCC ATCCATGAAT 
CCTGATGGGT ATGAAAAGTC CCAGGAAGGA GATTCAATAA GTGTAATTGG CAGAAACAAC 
AGCAACAACT TTGACCTGAA CCGAAATTTC CCAGACCAGT TTGTTCAGAT CACAGATCCT 
ACGCAACCAG AAACTATTGC TGTAATGAGC TGGATGAAGT CCTATCCATT TGTACTTTCA 
GCAAACCTGC ATGGAGGTTC TTTGGTGGTT AACTACCCTT TTGATGATGA TGAACAAGGA 
CTTGCCACAT ATAGTAAATC ACCAGATGAT GCTGTGTTCC AACAAATAGC ACTTTCTTAT 
TCCAAGGAAA ATTCCCAGAT GTTTCAAGGT AGACCTTGCA AGAATATGTA TCCTAATGAA 
TATTTTCCTC ATGGAATAAC AAATGGAGCT AGTTGGTATA ATGTGCCAGG AGGAATGCAG 
GACTGGAACT ATTTACAAAC AAATTGCTTT GAAGTGACTA TTGAACTAGG TTGTGTGAAA 
TATCCACTTG AGAAAGAGCT GCCAAACTTT TGGGAACAGA ATCGAAGATC ACTAATCCAG 
TTTATGAAAC AGGTTCATCA GGGCGTCAGA GGATTTGTTC TAGATGCCAC AGATGGCAGG 
GGTATATTAA ATGCCACCAT TAGTGTTGCT GAGATTAATC ACCCAGTGAC TACTTACAAA 
ACTGGAGATT ACTGGCGTCT CTTGGTTCCA GGAACTTATA AAATCACAGC ATCTGCTCGA 
GGGTATAATC CAGTTACCAA GAATGTGACT GTCAAGAGTG AAGGCGCTAT TCAGGTCAAC 
TTCACACTTG TTCGATCCTC AACAGATTCA AACAATGAAT CAAAGAAAGG AAAAGGGGCT 
AGCAGCAGCA CCAATGATGC CAGTGATCCA ACTACTAAAG AGTTTGAAAC TTTAATTAAA 
GACCTTTCAG CGGAGAATGG TTTGGAAAGC CTCATGTTAC GCTCCTCCTC AAATCTGGCT 
CTGGCTCTTT ATCGATACCA TTCCTACAAA GACTTATCAG AGTTTCTGAG AGGACTTGTA 
ATGAACTATC CACATATTAC AAATCTTACC AATTTGGGAC AGAGCACTGA ATATCGTCAC 
ATTTGGTCCC TTGAAATCTC CAATAAGCCC AATGTATCTG AGCCTGAAGA ACCAAAGATT 
CGTTTTGTTG CTGGTATCCA TGGAAATGCG CCAGTTGGAA CTGAACTGCT TTTGGCTCTG 
GCAGAATTTC TCTGCCTGAA CTACAAAAAG AACCCAGCTG TTACCCAATT GGTTGACAGG 
ACTAGGATTG TGATTGTCCC TTCTCTAAAT CCAGATGGGC GAGAGAGAGC TCAAGAGAAA 
GACTGTACTT CAAAAATAGG ACAAACAAAT GCTCGTGGCA AAGATTTGGA TACAGACTTC 
ACAAATAATG CCTCCCAACC TGAGACCAAA GCCATCATTG AAAATTTGAT TCAAAAACAG 
GACTTTAGTC TTTCTGTTGC CTTAGATGGT GGTTCCATGC TGGTCACATA TCCTTATGAC 
AAGCCAGTAC AGACAGTGGA AAATAAAGAG ACTCTGAAGC ATTTGGCATC TCTTTATGCA 
AATAATCATC CATCCATGCA CATGGGTCAG CCCAGTTGCC CAAATAAATC AGATGAGAAT 
ATTCCAGGAG GAGTAATGCG TGGAGCAGAA TGGCATAGTC ACCTGGGCAG CATGAAGGAT 
TATAGTGTCA CCTATGGCCA TTGTCCGGAA ATCACAGTAT ACACAAGCTG CTGTTACTTT 
CCTAGTGCTG CACGACTCCC TTCCTTGTGG GCAGACAATA AGAGATCTCT TCTTAGTATG 
TTAGTGGAGG TTCACAAGGG AGTTCATGGA TTTGTTAAAG ATAAGACTGG AAAGCCAATC 
TCTAAAGCAG TCATTGTACT TAATGAAGGA ATAAAGGTAC AAACAAAAGA GGGAGGTTAT 
TTCCATGTAC TCTTAGCGCC AGGTGTCCAT AACATTATTG CCATCGCTGA TGGGTACCAG 
CAACAACATT CACAGGTCTT TGTGCATCAT GATGCAGCTA GTTCTGTGGT GATAGTCTTT 
GACACAGATA ACCGGATATT TGGTTTGCCA AGGGAGCTTG TGGTAACTGT ATCAGGTGCT 
ACTATGTCGG CATTGATCCT AACAGCTTGC ATTATTTGGT GCATCTGCTC AATCAAGTCT 
AATAGACACA AGGATGGCTT TCATCGGCTC AGGCAGCATC ATGATGAGTA TGAAGATGAA 
ATTCGCATGA TGTCTACCGG CTCCAAGAAG TCCCTCCTAA GCCATGAGTT CCAGGATGAA 
ACAGACACTG AAGAGGAAAC ATTATATTCT AGCAAACATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186704.1
CDS	161..3562
Translation	MRFVLSGNLHGGSVVASYPFDDSPEHKATGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEGGMQDYNYVWANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENATISVAGINHNITTGRFGDFYRLLVPGTYNLTVVLTGYMPLTVTNVVVKEGPATEVDFSLRPTVTSVIPDTTEAVSTASTVAIPNILSGTSSSYQPIQPKDFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSISVIGRNNSNNFDLNRNFPDQFVQITDPTQPETIAVMSWMKSYPFVLSANLHGGSLVVNYPFDDDEQGLATYSKSPDDAVFQQIALSYSKENSQMFQGRPCKNMYPNEYFPHGITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPLEKELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATDGRGILNATISVAEINHPVTTYKTGDYWRLLVPGTYKITASARGYNPVTKNVTVKSEGAIQVNFTLVRSSTDSNNESKKGKGASSSTNDASDPTTKEFETLIKDLSAENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNYKKNPAVTQLVDRTRIVIVPSLNPDGRERAQEKDCTSKIGQTNARGKDLDTDFTNNASQPETKAIIENLIQKQDFSLSVALDGGSMLVTYPYDKPVQTVENKETLKHLASLYANNHPSMHMGQPSCPNKSDENIPGGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSCCYFPSAARLPSLWADNKRSLLSMLVEVHKGVHGFVKDKTGKPISKAVIVLNEGIKVQTKEGGYFHVLLAPGVHNIIAIADGYQQQHSQVFVHHDAASSVVIVFDTDNRIFGLPRELVVTVSGATMSALILTACIIWCICSIKSNRHKDGFHRLRQHHDEYEDEIRMMSTGSKKSLLSHEFQDETDTEEETLYSSKH

Target ORF information:

RefSeq Version	NM_001199775.1
Organism	Homo sapiens(human)
Definition	Homo sapiens carboxypeptidase D (CPD), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199775.1

ORF Insert Sequence:

ATGAGGTTTG TGCTTTCTGG AAATCTGCAT GGTGGCTCAG TGGTAGCAAG CTATCCTTTT 
GATGATTCTC CAGAACATAA GGCCACTGGA ATCTATAGCA AAACCTCAGA TGATGAAGTA 
TTTAAATACT TGGCAAAAGC TTATGCTTCA AACCACCCCA TAATGAAAAC TGGTGAGCCT 
CATTGTCCAG GAGATGAAGA CGAGACTTTC AAAGATGGAA TCACAAACGG CGCACATTGG 
TATGATGTGG AAGGTGGTAT GCAAGATTAC AATTATGTGT GGGCCAACTG TTTTGAGATC 
ACATTAGAAC TGTCTTGTTG CAAGTACCCA CCTGCTTCAC AGCTTCGACA GGAATGGGAG 
AACAATCGTG AGTCTTTGAT CACATTGATT GAAAAGGTTC ACATTGGAGT GAAAGGATTT 
GTTAAAGATT CCATAACAGG ATCTGGGTTA GAGAATGCAA CCATCTCAGT GGCTGGTATT 
AATCATAATA TCACAACAGG CAGATTTGGT GATTTCTACC GATTACTTGT TCCTGGAACT 
TACAACCTTA CAGTAGTTTT AACTGGGTAT ATGCCATTGA CTGTTACTAA TGTAGTGGTG 
AAAGAAGGAC CAGCCACAGA GGTGGATTTT TCTCTTAGGC CAACTGTAAC TTCAGTAATC 
CCTGACACGA CAGAGGCTGT ATCAACTGCT AGCACAGTTG CTATACCTAA TATTCTTTCT 
GGAACATCAT CCTCCTACCA GCCAATTCAG CCAAAGGACT TTCACCACCA CCATTTCCCT 
GATATGGAAA TCTTCTTGAG AAGGTTTGCC AATGAATATC CTAACATTAC CCGGCTTTAT 
TCCTTGGGAA AATCAGTAGA GTCAAGAGAA CTTTATGTGA TGGAGATATC TGATAATCCG 
GGTGTCCATG AACCAGGTGA ACCAGAATTT AAGTACATTG GAAATATGCA TGGAAATGAA 
GTGGTTGGAA GAGAACTGCT GTTGAACCTC ATAGAATACC TTTGTAAGAA CTTTGGAACA 
GACCCTGAAG TCACAGATTT GGTTCATAAC ACTAGAATTC ACCTTATGCC ATCCATGAAT 
CCTGATGGGT ATGAAAAGTC CCAGGAAGGA GATTCAATAA GTGTAATTGG CAGAAACAAC 
AGCAACAACT TTGACCTGAA CCGAAATTTC CCAGACCAGT TTGTTCAGAT CACAGATCCT 
ACGCAACCAG AAACTATTGC TGTAATGAGC TGGATGAAGT CCTATCCATT TGTACTTTCA 
GCAAACCTGC ATGGAGGTTC TTTGGTGGTT AACTACCCTT TTGATGATGA TGAACAAGGA 
CTTGCCACAT ATAGTAAATC ACCAGATGAT GCTGTGTTCC AACAAATAGC ACTTTCTTAT 
TCCAAGGAAA ATTCCCAGAT GTTTCAAGGT AGACCTTGCA AGAATATGTA TCCTAATGAA 
TATTTTCCTC ATGGAATAAC AAATGGAGCT AGTTGGTATA ATGTGCCAGG AGGAATGCAG 
GACTGGAACT ATTTACAAAC AAATTGCTTT GAAGTGACTA TTGAACTAGG TTGTGTGAAA 
TATCCACTTG AGAAAGAGCT GCCAAACTTT TGGGAACAGA ATCGAAGATC ACTAATCCAG 
TTTATGAAAC AGGTTCATCA GGGCGTCAGA GGATTTGTTC TAGATGCCAC AGATGGCAGG 
GGTATATTAA ATGCCACCAT TAGTGTTGCT GAGATTAATC ACCCAGTGAC TACTTACAAA 
ACTGGAGATT ACTGGCGTCT CTTGGTTCCA GGAACTTATA AAATCACAGC ATCTGCTCGA 
GGGTATAATC CAGTTACCAA GAATGTGACT GTCAAGAGTG AAGGCGCTAT TCAGGTCAAC 
TTCACACTTG TTCGATCCTC AACAGATTCA AACAATGAAT CAAAGAAAGG AAAAGGGGCT 
AGCAGCAGCA CCAATGATGC CAGTGATCCA ACTACTAAAG AGTTTGAAAC TTTAATTAAA 
GACCTTTCAG CGGAGAATGG TTTGGAAAGC CTCATGTTAC GCTCCTCCTC AAATCTGGCT 
CTGGCTCTTT ATCGATACCA TTCCTACAAA GACTTATCAG AGTTTCTGAG AGGACTTGTA 
ATGAACTATC CACATATTAC AAATCTTACC AATTTGGGAC AGAGCACTGA ATATCGTCAC 
ATTTGGTCCC TTGAAATCTC CAATAAGCCC AATGTATCTG AGCCTGAAGA ACCAAAGATT 
CGTTTTGTTG CTGGTATCCA TGGAAATGCG CCAGTTGGAA CTGAACTGCT TTTGGCTCTG 
GCAGAATTTC TCTGCCTGAA CTACAAAAAG AACCCAGCTG TTACCCAATT GGTTGACAGG 
ACTAGGATTG TGATTGTCCC TTCTCTAAAT CCAGATGGGC GAGAGAGAGC TCAAGAGAAA 
GACTGTACTT CAAAAATAGG ACAAACAAAT GCTCGTGGCA AAGATTTGGA TACAGACTTC 
ACAAATAATG CCTCCCAACC TGAGACCAAA GCCATCATTG AAAATTTGAT TCAAAAACAG 
GACTTTAGTC TTTCTGTTGC CTTAGATGGT GGTTCCATGC TGGTCACATA TCCTTATGAC 
AAGCCAGTAC AGACAGTGGA AAATAAAGAG ACTCTGAAGC ATTTGGCATC TCTTTATGCA 
AATAATCATC CATCCATGCA CATGGGTCAG CCCAGTTGCC CAAATAAATC AGATGAGAAT 
ATTCCAGGAG GAGTAATGCG TGGAGCAGAA TGGCATAGTC ACCTGGGCAG CATGAAGGAT 
TATAGTGTCA CCTATGGCCA TTGTCCGGAA ATCACAGTAT ACACAAGCTG CTGTTACTTT 
CCTAGTGCTG CACGACTCCC TTCCTTGTGG GCAGACAATA AGAGATCTCT TCTTAGTATG 
TTAGTGGAGG TTCACAAGGG AGTTCATGGA TTTGTTAAAG ATAAGACTGG AAAGCCAATC 
TCTAAAGCAG TCATTGTACT TAATGAAGGA ATAAAGGTAC AAACAAAAGA GGGAGGTTAT 
TTCCATGTAC TCTTAGCGCC AGGTGTCCAT AACATTATTG CCATCGCTGA TGGGTACCAG 
CAACAACATT CACAGGTCTT TGTGCATCAT GATGCAGCTA GTTCTGTGGT GATAGTCTTT 
GACACAGATA ACCGGATATT TGGTTTGCCA AGGGAGCTTG TGGTAACTGT ATCAGGTGCT 
ACTATGTCGG CATTGATCCT AACAGCTTGC ATTATTTGGT GCATCTGCTC AATCAAGTCT 
AATAGACACA AGGATGGCTT TCATCGGCTC AGGCAGCATC ATGATGAGTA TGAAGATGAA 
ATTCGCATGA TGTCTACCGG CTCCAAGAAG TCCCTCCTAA GCCATGAGTT CCAGGATGAA 
ACAGACACTG AAGAGGAAAC ATTATATTCT AGCAAACATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Prolactin/androgen-inducible carboxypeptidase-D increases with nitrotyrosine and Ki67 for breast cancer progression in vivo, and upregulates progression markers VEGF-C and Runx2 in vitro.
Breast cancer research and treatment164(1)27-40(2017 Jul)
Thomas LN,Chedrawe ER,Barnes PJ,Too CKL

microRNA-214 Governs Lung Cancer Growth and Metastasis by Targeting Carboxypeptidase-D.
DNA and cell biology35(11)715-721(2016 Nov)
Zhao X,Lu C,Chu W,Zhang Y,Zhang B,Zeng Q,Wang R,Li Z,Lv B,Liu J

Amyloid formation by human carboxypeptidase D transthyretin-like domain under physiological conditions.
The Journal of biological chemistry289(49)33783-96(2014 Dec)
Garcia-Pardo J,Gra?a-Montes R,Fernandez-Mendez M,Ruyra A,Roher N,Aviles FX,Lorenzo J,Ventura S

Carboxypeptidase-D is elevated in prostate cancer and its anti-apoptotic activity is abolished by combined androgen and prolactin receptor targeting.
The Prostate74(7)732-42(2014 May)
Thomas LN,Merrimen J,Bell DG,Rendon R,Goffin V,Too CK

Prolactin/Stat5 and androgen R1881 coactivate carboxypeptidase-D gene in breast cancer cells.
Molecular endocrinology (Baltimore, Md.)28(3)331-43(2014 Mar)
Koirala S,Thomas LN,Too CK

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CPD cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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