Gene Symbol | ADH1C |
Entrez Gene ID | 126 |
Full Name | alcohol dehydrogenase 1C (class I), gamma polypeptide |
Synonyms | ADH3 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | {Alcohol dependence, protection against}, 103780 (3); {Parkinson disease, susceptibility to}, 168600 (3) |