USH1G cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	USH1G
Entrez Gene ID	124590
Full Name	USH1 protein network component sans
Synonyms	ANKS4A,SANS
General protein information	Preferred Names USH1 protein network component sans Names Usher syndrome type-1G protein Usher syndrome 1G (autosomal recessive) scaffold protein containing ankyrin repeats and SAM domain
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q25.1
Summary	This gene encodes a protein that contains three ankyrin domains, a class I PDZ-binding motif and a sterile alpha motif. The encoded protein interacts with harmonin, which is associated with Usher syndrome type 1C. This protein plays a role in the development and maintenance of the auditory and visual systems and functions in the cohesion of hair bundles formed by inner ear sensory cells. Mutations in this gene are associated with Usher syndrome type 1G (USH1G). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013].
Disorder MIM:	607696
Disorder Html:	Usher syndrome, type 1G, 606943 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_011524296.2	XP_011522598.1	Usher syndrome type-1G protein isoform X1
XM_011524296.1	XP_011522598.1	Usher syndrome type-1G protein isoform X1
NM_173477.4	NP_775748.2	Usher syndrome type-1G protein isoform 1
NM_001282489.2	NP_001269418.1	Usher syndrome type-1G protein isoform 2
NM_173477.5	NP_775748.2	Usher syndrome type-1G protein isoform 1
NM_001282489.3	NP_001269418.1	Usher syndrome type-1G protein isoform 2

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Ush1g	NP_001099320.1
Gallus gallus (chicken)	USH1G	XP_426242.2
Canis lupus familiaris (dog)	USH1G	XP_852112.2
Mus musculus (house mouse)	Ush1g	NP_789817.1
Drosophila melanogaster (fruit fly)	Sans	NP_788340.1
Homo sapiens (human)	USH1G	NP_775748.2
Pan troglodytes (chimpanzee)	USH1G	XP_523715.2
Danio rerio (zebrafish)	LOC100330314	XP_002661315.1
Xenopus tropicalis (tropical clawed frog)	ush1g	XP_002939606.1
Bos taurus (cattle)	USH1G	NP_001179631.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007027	XP_308746.4

Gene Ontology
Bibliography

Related articles in PubMed

Myosin 7 and its adaptors link cadherins to actin.
Yu IM, Planelles-Herrero VJ, Sourigues Y, Moussaoui D, Sirkia H, Kikuti C, Stroebel D, Titus MA, Houdusse A
Nature communications815864(2017 Jun)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Characterization of the ternary Usher syndrome SANS/ush2a/whirlin protein complex.
Sorusch N, Bau? K, Plutniok J, Samanta A, Knapp B, Nagel-Wolfrum K, Wolfrum U
Human molecular genetics26(6)1157-1172(2017 03)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Protein-protein interaction assays and co-expression of complex partners reveal that pathogenic mutations in USH1G severely affect formation of the SANS/ush2a/whirlin complex. Translational read-through drug treatment, targeting the c.728C > A (p.S243X) nonsense mutation, restored SANS scaffold function. We conclude that USH1 and USH2 proteins function together in higher order protein complexes.
Title: Characterization of the ternary Usher syndrome SANS/ush2a/whirlin protein complex.

USH1G caused a non-syndromic hearing loss in a Dutch family. Compound heterozygous mutations in USH1G were found to segregate with the hearing loss, a missense (c.310A>G, p.Met104Val) and a frameshift mutation (c.780insGCAC, p.Tyr261Alafs*96).
Title: Nonsyndromic hearing loss caused by USH1G mutations: widening the USH1G disease spectrum.

In USH1G patients, mutations in SANS eliminate Magi2 binding and thereby deregulate endocytosis, lead to defective ciliary transport modules and ultimately disrupt photoreceptor cell function inducing retinal degeneration.
Title: Phosphorylation of the Usher syndrome 1G protein SANS controls Magi2-mediated endocytosis.

A novel p.S243X truncating mutation in USH1G that segregated with the disease phenotype has been identified in consanguineous Saudi Arabia siblings.
Title: USH1G with unique retinal findings caused by a novel truncating mutation identified by genome-wide linkage analysis.

Pathogenic mutations in MYO7A, USH1C, and USH1G have been found in four consanguineous Israeli Arab families with Usher syndrome type 1.
Title: Novel mutations of MYO7A and USH1G in Israeli Arab families with Usher syndrome type 1.

The following USH1G gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the USH1G cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23504	NM_001282489.3 Latest version!	Homo sapiens USH1 protein network component sans (USH1G), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu24077	NM_173477.5 Latest version!	Homo sapiens USH1 protein network component sans (USH1G), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu23504	XM_011524296.2 Latest version!	Homo sapiens USH1 protein network component sans (USH1G), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu23504	XM_011524296.1	Homo sapiens Usher syndrome 1G (autosomal recessive) (USH1G), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu24077	NM_173477.4	Homo sapiens USH1 protein network component sans (USH1G), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu23504	NM_001282489.2	Homo sapiens USH1 protein network component sans (USH1G), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

USH1G ( NM_001282489.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269418.1 Homo sapiens USH1 protein network component sans (USH1G), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu23504
Clone ID Related Accession (Same CDS sequence)	XM_011524296.2 , XM_011524296.1 , NM_001282489.2 , NM_001282489.3
Accession Version	NM_001282489.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1077bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	Usher syndrome type-1G protein isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC403891.1, AK296899.1, BC101096.2 and AC087651.19. On Mar 25, 2014 this sequence version replaced NM_001282489.1. Transcript Variant: This variant (2) differs in its 5' UTR and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK296899.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2148093 [ECO:0000350] ##Evidence-Data-END##

ATGGCTGCCA TGAAGGGCCA CATGGAATGC GTGCGCTACC TGGACTCCAT CGCGGCCAAG 
CAGAGCAGCC TCAACCCCAA GCTGGTGGGT AAGCTGAAGG ACAAGGCCTT CCGCGAGGCG 
GAGCGGCGCA TCCGCGAGTG CGCCAAGCTG CAGCGGAGGC ACCACGAACG CATGGAGCGG 
CGATACCGGC GCGAGCTGGC CGAGCGTTCC GACACCCTCA GCTTCTCCAG CCTCACGTCC 
AGCACCCTGA GCCGCCGGCT GCAGCATCTG GCGCTGGGCA GCCACCTGCC GTACTCTCAG 
GCCACGCTGC ACGGCACGGC CAGGGGCAAG ACCAAGATGC AGAAGAAGCT GGAGCGGCGC 
AAGCAGGGCG GCGAAGGCAC CTTCAAGGTC TCCGAGGATG GGCGCAAGAG CGCCCGCTCG 
CTCTCGGGCC TGCAGCTGGG CAGCGACGTG ATGTTCGTGC GCCAGGGCAC CTACGCCAAT 
CCCAAGGAGT GGGGCCGAGC CCCGCTCCGG GACATGTTCC TCTCGGACGA GGACAGCGTC 
TCCCGTGCCA CGCTGGCGGC CGAGCCTGCC CACTCGGAGG TCAGCACCGA CTCAGGCCAC 
GACTCCCTGT TTACCCGCCC CGGCCTGGGC ACCATGGTGT TCCGCAGAAA TTACTTGAGC 
AGTGGGCTGC ACGGACTGGG CCGCGAGGAT GGGGGTCTGG ATGGGGTGGG AGCGCCGCGG 
GGTCGGCTGC AGAGCTCCCC CAGCCTGGAC GATGACAGCC TGGGCAGTGC CAACAGCCTG 
CAGGACCGCA GCTGTGGGGA GGAGCTGCCC TGGGATGAGC TCGATTTAGG CTTGGACGAG 
GACCTGGAGC CCGAGACTAG CCCGCTGGAG ACCTTCCTGG CCTCTCTGCA CATGGAGGAC 
TTTGCCGCCC TCCTGCGGCA GGAGAAGATC GACCTCGAGG CTTTGATGCT GTGCTCTGAC 
CTCGACCTCC GCAGCATCAG CGTCCCACTG GGGCCCCGAA AGAAGATCTT GGGGGCCGTG 
AGGAGGCGGC GGCAGGCGAT GGAGCGCCCG CCGGCCCTGG AGGACACAGA GCTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269418.1
CDS	447..1523
Translation	MAAMKGHMECVRYLDSIAAKQSSLNPKLVGKLKDKAFREAERRIRECAKLQRRHHERMERRYRRELAERSDTLSFSSLTSSTLSRRLQHLALGSHLPYSQATLHGTARGKTKMQKKLERRKQGGEGTFKVSEDGRKSARSLSGLQLGSDVMFVRQGTYANPKEWGRAPLRDMFLSDEDSVSRATLAAEPAHSEVSTDSGHDSLFTRPGLGTMVFRRNYLSSGLHGLGREDGGLDGVGAPRGRLQSSPSLDDDSLGSANSLQDRSCGEELPWDELDLGLDEDLEPETSPLETFLASLHMEDFAALLRQEKIDLEALMLCSDLDLRSISVPLGPRKKILGAVRRRRQAMERPPALEDTEL

Target ORF information:

RefSeq Version	NM_001282489.2
Organism	Homo sapiens(human)
Definition	Homo sapiens USH1 protein network component sans (USH1G), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282489.2

ORF Insert Sequence:

ATGGCTGCCA TGAAGGGCCA CATGGAATGC GTGCGCTACC TGGACTCCAT CGCGGCCAAG 
CAGAGCAGCC TCAACCCCAA GCTGGTGGGT AAGCTGAAGG ACAAGGCCTT CCGCGAGGCG 
GAGCGGCGCA TCCGCGAGTG CGCCAAGCTG CAGCGGAGGC ACCACGAACG CATGGAGCGG 
CGATACCGGC GCGAGCTGGC CGAGCGTTCC GACACCCTCA GCTTCTCCAG CCTCACGTCC 
AGCACCCTGA GCCGCCGGCT GCAGCATCTG GCGCTGGGCA GCCACCTGCC GTACTCTCAG 
GCCACGCTGC ACGGCACGGC CAGGGGCAAG ACCAAGATGC AGAAGAAGCT GGAGCGGCGC 
AAGCAGGGCG GCGAAGGCAC CTTCAAGGTC TCCGAGGATG GGCGCAAGAG CGCCCGCTCG 
CTCTCGGGCC TGCAGCTGGG CAGCGACGTG ATGTTCGTGC GCCAGGGCAC CTACGCCAAT 
CCCAAGGAGT GGGGCCGAGC CCCGCTCCGG GACATGTTCC TCTCGGACGA GGACAGCGTC 
TCCCGTGCCA CGCTGGCGGC CGAGCCTGCC CACTCGGAGG TCAGCACCGA CTCAGGCCAC 
GACTCCCTGT TTACCCGCCC CGGCCTGGGC ACCATGGTGT TCCGCAGAAA TTACTTGAGC 
AGTGGGCTGC ACGGACTGGG CCGCGAGGAT GGGGGTCTGG ATGGGGTGGG AGCGCCGCGG 
GGTCGGCTGC AGAGCTCCCC CAGCCTGGAC GATGACAGCC TGGGCAGTGC CAACAGCCTG 
CAGGACCGCA GCTGTGGGGA GGAGCTGCCC TGGGATGAGC TCGATTTAGG CTTGGACGAG 
GACCTGGAGC CCGAGACTAG CCCGCTGGAG ACCTTCCTGG CCTCTCTGCA CATGGAGGAC 
TTTGCCGCCC TCCTGCGGCA GGAGAAGATC GACCTCGAGG CTTTGATGCT GTGCTCTGAC 
CTCGACCTCC GCAGCATCAG CGTCCCACTG GGGCCCCGAA AGAAGATCTT GGGGGCCGTG 
AGGAGGCGGC GGCAGGCGAT GGAGCGCCCG CCGGCCCTGG AGGACACAGA GCTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

USH1G ( NM_001282489.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269418.1 Homo sapiens USH1 protein network component sans (USH1G), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu23504
Clone ID Related Accession (Same CDS sequence)	XM_011524296.2 , XM_011524296.1 , NM_001282489.2 , NM_001282489.3
Accession Version	NM_001282489.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1077bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	Usher syndrome type-1G protein isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK296899.1, BC101096.2 and AC087651.19. On Jun 1, 2019 this sequence version replaced NM_001282489.2. Transcript Variant: This variant (2) differs in its 5' UTR and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK296899.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2148093 [ECO:0000350] ##Evidence-Data-END##

ATGGCTGCCA TGAAGGGCCA CATGGAATGC GTGCGCTACC TGGACTCCAT CGCGGCCAAG 
CAGAGCAGCC TCAACCCCAA GCTGGTGGGT AAGCTGAAGG ACAAGGCCTT CCGCGAGGCG 
GAGCGGCGCA TCCGCGAGTG CGCCAAGCTG CAGCGGAGGC ACCACGAACG CATGGAGCGG 
CGATACCGGC GCGAGCTGGC CGAGCGTTCC GACACCCTCA GCTTCTCCAG CCTCACGTCC 
AGCACCCTGA GCCGCCGGCT GCAGCATCTG GCGCTGGGCA GCCACCTGCC GTACTCTCAG 
GCCACGCTGC ACGGCACGGC CAGGGGCAAG ACCAAGATGC AGAAGAAGCT GGAGCGGCGC 
AAGCAGGGCG GCGAAGGCAC CTTCAAGGTC TCCGAGGATG GGCGCAAGAG CGCCCGCTCG 
CTCTCGGGCC TGCAGCTGGG CAGCGACGTG ATGTTCGTGC GCCAGGGCAC CTACGCCAAT 
CCCAAGGAGT GGGGCCGAGC CCCGCTCCGG GACATGTTCC TCTCGGACGA GGACAGCGTC 
TCCCGTGCCA CGCTGGCGGC CGAGCCTGCC CACTCGGAGG TCAGCACCGA CTCAGGCCAC 
GACTCCCTGT TTACCCGCCC CGGCCTGGGC ACCATGGTGT TCCGCAGAAA TTACTTGAGC 
AGTGGGCTGC ACGGACTGGG CCGCGAGGAT GGGGGTCTGG ATGGGGTGGG AGCGCCGCGG 
GGTCGGCTGC AGAGCTCCCC CAGCCTGGAC GATGACAGCC TGGGCAGTGC CAACAGCCTG 
CAGGACCGCA GCTGTGGGGA GGAGCTGCCC TGGGATGAGC TCGATTTAGG CTTGGACGAG 
GACCTGGAGC CCGAGACTAG CCCGCTGGAG ACCTTCCTGG CCTCTCTGCA CATGGAGGAC 
TTTGCCGCCC TCCTGCGGCA GGAGAAGATC GACCTCGAGG CTTTGATGCT GTGCTCTGAC 
CTCGACCTCC GCAGCATCAG CGTCCCACTG GGGCCCCGAA AGAAGATCTT GGGGGCCGTG 
AGGAGGCGGC GGCAGGCGAT GGAGCGCCCG CCGGCCCTGG AGGACACAGA GCTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269418.1
CDS	439..1515
Translation	MAAMKGHMECVRYLDSIAAKQSSLNPKLVGKLKDKAFREAERRIRECAKLQRRHHERMERRYRRELAERSDTLSFSSLTSSTLSRRLQHLALGSHLPYSQATLHGTARGKTKMQKKLERRKQGGEGTFKVSEDGRKSARSLSGLQLGSDVMFVRQGTYANPKEWGRAPLRDMFLSDEDSVSRATLAAEPAHSEVSTDSGHDSLFTRPGLGTMVFRRNYLSSGLHGLGREDGGLDGVGAPRGRLQSSPSLDDDSLGSANSLQDRSCGEELPWDELDLGLDEDLEPETSPLETFLASLHMEDFAALLRQEKIDLEALMLCSDLDLRSISVPLGPRKKILGAVRRRRQAMERPPALEDTEL

Target ORF information:

RefSeq Version	NM_001282489.3
Organism	Homo sapiens(human)
Definition	Homo sapiens USH1 protein network component sans (USH1G), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282489.3

ORF Insert Sequence:

ATGGCTGCCA TGAAGGGCCA CATGGAATGC GTGCGCTACC TGGACTCCAT CGCGGCCAAG 
CAGAGCAGCC TCAACCCCAA GCTGGTGGGT AAGCTGAAGG ACAAGGCCTT CCGCGAGGCG 
GAGCGGCGCA TCCGCGAGTG CGCCAAGCTG CAGCGGAGGC ACCACGAACG CATGGAGCGG 
CGATACCGGC GCGAGCTGGC CGAGCGTTCC GACACCCTCA GCTTCTCCAG CCTCACGTCC 
AGCACCCTGA GCCGCCGGCT GCAGCATCTG GCGCTGGGCA GCCACCTGCC GTACTCTCAG 
GCCACGCTGC ACGGCACGGC CAGGGGCAAG ACCAAGATGC AGAAGAAGCT GGAGCGGCGC 
AAGCAGGGCG GCGAAGGCAC CTTCAAGGTC TCCGAGGATG GGCGCAAGAG CGCCCGCTCG 
CTCTCGGGCC TGCAGCTGGG CAGCGACGTG ATGTTCGTGC GCCAGGGCAC CTACGCCAAT 
CCCAAGGAGT GGGGCCGAGC CCCGCTCCGG GACATGTTCC TCTCGGACGA GGACAGCGTC 
TCCCGTGCCA CGCTGGCGGC CGAGCCTGCC CACTCGGAGG TCAGCACCGA CTCAGGCCAC 
GACTCCCTGT TTACCCGCCC CGGCCTGGGC ACCATGGTGT TCCGCAGAAA TTACTTGAGC 
AGTGGGCTGC ACGGACTGGG CCGCGAGGAT GGGGGTCTGG ATGGGGTGGG AGCGCCGCGG 
GGTCGGCTGC AGAGCTCCCC CAGCCTGGAC GATGACAGCC TGGGCAGTGC CAACAGCCTG 
CAGGACCGCA GCTGTGGGGA GGAGCTGCCC TGGGATGAGC TCGATTTAGG CTTGGACGAG 
GACCTGGAGC CCGAGACTAG CCCGCTGGAG ACCTTCCTGG CCTCTCTGCA CATGGAGGAC 
TTTGCCGCCC TCCTGCGGCA GGAGAAGATC GACCTCGAGG CTTTGATGCT GTGCTCTGAC 
CTCGACCTCC GCAGCATCAG CGTCCCACTG GGGCCCCGAA AGAAGATCTT GGGGGCCGTG 
AGGAGGCGGC GGCAGGCGAT GGAGCGCCCG CCGGCCCTGG AGGACACAGA GCTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

USH1G ( NM_173477.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_775748.2 Homo sapiens USH1 protein network component sans (USH1G), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24077
Clone ID Related Accession (Same CDS sequence)	NM_173477.4 , NM_173477.5
Accession Version	NM_173477.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1386bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	Usher syndrome type-1G protein isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC403891.1, BC101096.2 and AC087651.19. This sequence is a reference standard in the RefSeqGene project. On Mar 25, 2014 this sequence version replaced NM_173477.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK091243.1, AK289804.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148093 [ECO:0000348] ##Evidence-Data-END##

ATGAACGACC AGTACCACCG GGCAGCCCGG GATGGCTACC TGGAGCTCCT CAAGGAGGCC 
ACCCGAAAGG AGCTGAATGC CCCCGACGAG GATGGCATGA CCCCCACTCT CTGGGCTGCC 
TACCATGGCA ACCTCGAGTC GCTGCGTCTC ATTGTGAGCC GCGGGGGTGA CCCGGACAAG 
TGTGACATCT GGGGCAACAC ACCCCTGCAT CTGGCAGCTT CCAATGGCCA CTTGCACTGC 
CTGTCCTTCC TGGTGTCCTT CGGAGCCAAC ATCTGGTGCC TAGACAACGA CTACCACACG 
CCGCTGGACA TGGCTGCCAT GAAGGGCCAC ATGGAATGCG TGCGCTACCT GGACTCCATC 
GCGGCCAAGC AGAGCAGCCT CAACCCCAAG CTGGTGGGTA AGCTGAAGGA CAAGGCCTTC 
CGCGAGGCGG AGCGGCGCAT CCGCGAGTGC GCCAAGCTGC AGCGGAGGCA CCACGAACGC 
ATGGAGCGGC GATACCGGCG CGAGCTGGCC GAGCGTTCCG ACACCCTCAG CTTCTCCAGC 
CTCACGTCCA GCACCCTGAG CCGCCGGCTG CAGCATCTGG CGCTGGGCAG CCACCTGCCG 
TACTCTCAGG CCACGCTGCA CGGCACGGCC AGGGGCAAGA CCAAGATGCA GAAGAAGCTG 
GAGCGGCGCA AGCAGGGCGG CGAAGGCACC TTCAAGGTCT CCGAGGATGG GCGCAAGAGC 
GCCCGCTCGC TCTCGGGCCT GCAGCTGGGC AGCGACGTGA TGTTCGTGCG CCAGGGCACC 
TACGCCAATC CCAAGGAGTG GGGCCGAGCC CCGCTCCGGG ACATGTTCCT CTCGGACGAG 
GACAGCGTCT CCCGTGCCAC GCTGGCGGCC GAGCCTGCCC ACTCGGAGGT CAGCACCGAC 
TCAGGCCACG ACTCCCTGTT TACCCGCCCC GGCCTGGGCA CCATGGTGTT CCGCAGAAAT 
TACTTGAGCA GTGGGCTGCA CGGACTGGGC CGCGAGGATG GGGGTCTGGA TGGGGTGGGA 
GCGCCGCGGG GTCGGCTGCA GAGCTCCCCC AGCCTGGACG ATGACAGCCT GGGCAGTGCC 
AACAGCCTGC AGGACCGCAG CTGTGGGGAG GAGCTGCCCT GGGATGAGCT CGATTTAGGC 
TTGGACGAGG ACCTGGAGCC CGAGACTAGC CCGCTGGAGA CCTTCCTGGC CTCTCTGCAC 
ATGGAGGACT TTGCCGCCCT CCTGCGGCAG GAGAAGATCG ACCTCGAGGC TTTGATGCTG 
TGCTCTGACC TCGACCTCCG CAGCATCAGC GTCCCACTGG GGCCCCGAAA GAAGATCTTG 
GGGGCCGTGA GGAGGCGGCG GCAGGCGATG GAGCGCCCGC CGGCCCTGGA GGACACAGAG 
CTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_775748.2
CDS	191..1576
Translation	MNDQYHRAARDGYLELLKEATRKELNAPDEDGMTPTLWAAYHGNLESLRLIVSRGGDPDKCDIWGNTPLHLAASNGHLHCLSFLVSFGANIWCLDNDYHTPLDMAAMKGHMECVRYLDSIAAKQSSLNPKLVGKLKDKAFREAERRIRECAKLQRRHHERMERRYRRELAERSDTLSFSSLTSSTLSRRLQHLALGSHLPYSQATLHGTARGKTKMQKKLERRKQGGEGTFKVSEDGRKSARSLSGLQLGSDVMFVRQGTYANPKEWGRAPLRDMFLSDEDSVSRATLAAEPAHSEVSTDSGHDSLFTRPGLGTMVFRRNYLSSGLHGLGREDGGLDGVGAPRGRLQSSPSLDDDSLGSANSLQDRSCGEELPWDELDLGLDEDLEPETSPLETFLASLHMEDFAALLRQEKIDLEALMLCSDLDLRSISVPLGPRKKILGAVRRRRQAMERPPALEDTEL

Target ORF information:

RefSeq Version	NM_173477.4
Organism	Homo sapiens(human)
Definition	Homo sapiens USH1 protein network component sans (USH1G), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173477.4

ORF Insert Sequence:

ATGAACGACC AGTACCACCG GGCAGCCCGG GATGGCTACC TGGAGCTCCT CAAGGAGGCC 
ACCCGAAAGG AGCTGAATGC CCCCGACGAG GATGGCATGA CCCCCACTCT CTGGGCTGCC 
TACCATGGCA ACCTCGAGTC GCTGCGTCTC ATTGTGAGCC GCGGGGGTGA CCCGGACAAG 
TGTGACATCT GGGGCAACAC ACCCCTGCAT CTGGCAGCTT CCAATGGCCA CTTGCACTGC 
CTGTCCTTCC TGGTGTCCTT CGGAGCCAAC ATCTGGTGCC TAGACAACGA CTACCACACG 
CCGCTGGACA TGGCTGCCAT GAAGGGCCAC ATGGAATGCG TGCGCTACCT GGACTCCATC 
GCGGCCAAGC AGAGCAGCCT CAACCCCAAG CTGGTGGGTA AGCTGAAGGA CAAGGCCTTC 
CGCGAGGCGG AGCGGCGCAT CCGCGAGTGC GCCAAGCTGC AGCGGAGGCA CCACGAACGC 
ATGGAGCGGC GATACCGGCG CGAGCTGGCC GAGCGTTCCG ACACCCTCAG CTTCTCCAGC 
CTCACGTCCA GCACCCTGAG CCGCCGGCTG CAGCATCTGG CGCTGGGCAG CCACCTGCCG 
TACTCTCAGG CCACGCTGCA CGGCACGGCC AGGGGCAAGA CCAAGATGCA GAAGAAGCTG 
GAGCGGCGCA AGCAGGGCGG CGAAGGCACC TTCAAGGTCT CCGAGGATGG GCGCAAGAGC 
GCCCGCTCGC TCTCGGGCCT GCAGCTGGGC AGCGACGTGA TGTTCGTGCG CCAGGGCACC 
TACGCCAATC CCAAGGAGTG GGGCCGAGCC CCGCTCCGGG ACATGTTCCT CTCGGACGAG 
GACAGCGTCT CCCGTGCCAC GCTGGCGGCC GAGCCTGCCC ACTCGGAGGT CAGCACCGAC 
TCAGGCCACG ACTCCCTGTT TACCCGCCCC GGCCTGGGCA CCATGGTGTT CCGCAGAAAT 
TACTTGAGCA GTGGGCTGCA CGGACTGGGC CGCGAGGATG GGGGTCTGGA TGGGGTGGGA 
GCGCCGCGGG GTCGGCTGCA GAGCTCCCCC AGCCTGGACG ATGACAGCCT GGGCAGTGCC 
AACAGCCTGC AGGACCGCAG CTGTGGGGAG GAGCTGCCCT GGGATGAGCT CGATTTAGGC 
TTGGACGAGG ACCTGGAGCC CGAGACTAGC CCGCTGGAGA CCTTCCTGGC CTCTCTGCAC 
ATGGAGGACT TTGCCGCCCT CCTGCGGCAG GAGAAGATCG ACCTCGAGGC TTTGATGCTG 
TGCTCTGACC TCGACCTCCG CAGCATCAGC GTCCCACTGG GGCCCCGAAA GAAGATCTTG 
GGGGCCGTGA GGAGGCGGCG GCAGGCGATG GAGCGCCCGC CGGCCCTGGA GGACACAGAG 
CTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

USH1G ( NM_173477.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_775748.2 Homo sapiens USH1 protein network component sans (USH1G), transcript variant 1, mRNA.

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CloneID	OHu24077
Clone ID Related Accession (Same CDS sequence)	NM_173477.4 , NM_173477.5
Accession Version	NM_173477.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1386bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	Usher syndrome type-1G protein isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC403891.1, BC101096.2 and AC087651.19. This sequence is a reference standard in the RefSeqGene project. On Nov 24, 2018 this sequence version replaced NM_173477.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK091243.1, AK289804.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000614341.5/ ENSP00000480279.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAACGACC AGTACCACCG GGCAGCCCGG GATGGCTACC TGGAGCTCCT CAAGGAGGCC 
ACCCGAAAGG AGCTGAATGC CCCCGACGAG GATGGCATGA CCCCCACTCT CTGGGCTGCC 
TACCATGGCA ACCTCGAGTC GCTGCGTCTC ATTGTGAGCC GCGGGGGTGA CCCGGACAAG 
TGTGACATCT GGGGCAACAC ACCCCTGCAT CTGGCAGCTT CCAATGGCCA CTTGCACTGC 
CTGTCCTTCC TGGTGTCCTT CGGAGCCAAC ATCTGGTGCC TAGACAACGA CTACCACACG 
CCGCTGGACA TGGCTGCCAT GAAGGGCCAC ATGGAATGCG TGCGCTACCT GGACTCCATC 
GCGGCCAAGC AGAGCAGCCT CAACCCCAAG CTGGTGGGTA AGCTGAAGGA CAAGGCCTTC 
CGCGAGGCGG AGCGGCGCAT CCGCGAGTGC GCCAAGCTGC AGCGGAGGCA CCACGAACGC 
ATGGAGCGGC GATACCGGCG CGAGCTGGCC GAGCGTTCCG ACACCCTCAG CTTCTCCAGC 
CTCACGTCCA GCACCCTGAG CCGCCGGCTG CAGCATCTGG CGCTGGGCAG CCACCTGCCG 
TACTCTCAGG CCACGCTGCA CGGCACGGCC AGGGGCAAGA CCAAGATGCA GAAGAAGCTG 
GAGCGGCGCA AGCAGGGCGG CGAAGGCACC TTCAAGGTCT CCGAGGATGG GCGCAAGAGC 
GCCCGCTCGC TCTCGGGCCT GCAGCTGGGC AGCGACGTGA TGTTCGTGCG CCAGGGCACC 
TACGCCAATC CCAAGGAGTG GGGCCGAGCC CCGCTCCGGG ACATGTTCCT CTCGGACGAG 
GACAGCGTCT CCCGTGCCAC GCTGGCGGCC GAGCCTGCCC ACTCGGAGGT CAGCACCGAC 
TCAGGCCACG ACTCCCTGTT TACCCGCCCC GGCCTGGGCA CCATGGTGTT CCGCAGAAAT 
TACTTGAGCA GTGGGCTGCA CGGACTGGGC CGCGAGGATG GGGGTCTGGA TGGGGTGGGA 
GCGCCGCGGG GTCGGCTGCA GAGCTCCCCC AGCCTGGACG ATGACAGCCT GGGCAGTGCC 
AACAGCCTGC AGGACCGCAG CTGTGGGGAG GAGCTGCCCT GGGATGAGCT CGATTTAGGC 
TTGGACGAGG ACCTGGAGCC CGAGACTAGC CCGCTGGAGA CCTTCCTGGC CTCTCTGCAC 
ATGGAGGACT TTGCCGCCCT CCTGCGGCAG GAGAAGATCG ACCTCGAGGC TTTGATGCTG 
TGCTCTGACC TCGACCTCCG CAGCATCAGC GTCCCACTGG GGCCCCGAAA GAAGATCTTG 
GGGGCCGTGA GGAGGCGGCG GCAGGCGATG GAGCGCCCGC CGGCCCTGGA GGACACAGAG 
CTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_775748.2
CDS	183..1568
Translation	MNDQYHRAARDGYLELLKEATRKELNAPDEDGMTPTLWAAYHGNLESLRLIVSRGGDPDKCDIWGNTPLHLAASNGHLHCLSFLVSFGANIWCLDNDYHTPLDMAAMKGHMECVRYLDSIAAKQSSLNPKLVGKLKDKAFREAERRIRECAKLQRRHHERMERRYRRELAERSDTLSFSSLTSSTLSRRLQHLALGSHLPYSQATLHGTARGKTKMQKKLERRKQGGEGTFKVSEDGRKSARSLSGLQLGSDVMFVRQGTYANPKEWGRAPLRDMFLSDEDSVSRATLAAEPAHSEVSTDSGHDSLFTRPGLGTMVFRRNYLSSGLHGLGREDGGLDGVGAPRGRLQSSPSLDDDSLGSANSLQDRSCGEELPWDELDLGLDEDLEPETSPLETFLASLHMEDFAALLRQEKIDLEALMLCSDLDLRSISVPLGPRKKILGAVRRRRQAMERPPALEDTEL

Target ORF information:

RefSeq Version	NM_173477.5
Organism	Homo sapiens(human)
Definition	Homo sapiens USH1 protein network component sans (USH1G), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173477.5

ORF Insert Sequence:

ATGAACGACC AGTACCACCG GGCAGCCCGG GATGGCTACC TGGAGCTCCT CAAGGAGGCC 
ACCCGAAAGG AGCTGAATGC CCCCGACGAG GATGGCATGA CCCCCACTCT CTGGGCTGCC 
TACCATGGCA ACCTCGAGTC GCTGCGTCTC ATTGTGAGCC GCGGGGGTGA CCCGGACAAG 
TGTGACATCT GGGGCAACAC ACCCCTGCAT CTGGCAGCTT CCAATGGCCA CTTGCACTGC 
CTGTCCTTCC TGGTGTCCTT CGGAGCCAAC ATCTGGTGCC TAGACAACGA CTACCACACG 
CCGCTGGACA TGGCTGCCAT GAAGGGCCAC ATGGAATGCG TGCGCTACCT GGACTCCATC 
GCGGCCAAGC AGAGCAGCCT CAACCCCAAG CTGGTGGGTA AGCTGAAGGA CAAGGCCTTC 
CGCGAGGCGG AGCGGCGCAT CCGCGAGTGC GCCAAGCTGC AGCGGAGGCA CCACGAACGC 
ATGGAGCGGC GATACCGGCG CGAGCTGGCC GAGCGTTCCG ACACCCTCAG CTTCTCCAGC 
CTCACGTCCA GCACCCTGAG CCGCCGGCTG CAGCATCTGG CGCTGGGCAG CCACCTGCCG 
TACTCTCAGG CCACGCTGCA CGGCACGGCC AGGGGCAAGA CCAAGATGCA GAAGAAGCTG 
GAGCGGCGCA AGCAGGGCGG CGAAGGCACC TTCAAGGTCT CCGAGGATGG GCGCAAGAGC 
GCCCGCTCGC TCTCGGGCCT GCAGCTGGGC AGCGACGTGA TGTTCGTGCG CCAGGGCACC 
TACGCCAATC CCAAGGAGTG GGGCCGAGCC CCGCTCCGGG ACATGTTCCT CTCGGACGAG 
GACAGCGTCT CCCGTGCCAC GCTGGCGGCC GAGCCTGCCC ACTCGGAGGT CAGCACCGAC 
TCAGGCCACG ACTCCCTGTT TACCCGCCCC GGCCTGGGCA CCATGGTGTT CCGCAGAAAT 
TACTTGAGCA GTGGGCTGCA CGGACTGGGC CGCGAGGATG GGGGTCTGGA TGGGGTGGGA 
GCGCCGCGGG GTCGGCTGCA GAGCTCCCCC AGCCTGGACG ATGACAGCCT GGGCAGTGCC 
AACAGCCTGC AGGACCGCAG CTGTGGGGAG GAGCTGCCCT GGGATGAGCT CGATTTAGGC 
TTGGACGAGG ACCTGGAGCC CGAGACTAGC CCGCTGGAGA CCTTCCTGGC CTCTCTGCAC 
ATGGAGGACT TTGCCGCCCT CCTGCGGCAG GAGAAGATCG ACCTCGAGGC TTTGATGCTG 
TGCTCTGACC TCGACCTCCG CAGCATCAGC GTCCCACTGG GGCCCCGAAA GAAGATCTTG 
GGGGCCGTGA GGAGGCGGCG GCAGGCGATG GAGCGCCCGC CGGCCCTGGA GGACACAGAG 
CTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

USH1G ( XM_011524296.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011522598.1 Homo sapiens USH1 protein network component sans (USH1G), transcript variant X1, mRNA.

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CloneID	OHu23504
Clone ID Related Accession (Same CDS sequence)	XM_011524296.2 , XM_011524296.1 , NM_001282489.2 , NM_001282489.3
Accession Version	XM_011524296.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1077bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	Usher syndrome type-1G protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011524296.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGCCA TGAAGGGCCA CATGGAATGC GTGCGCTACC TGGACTCCAT CGCGGCCAAG 
CAGAGCAGCC TCAACCCCAA GCTGGTGGGT AAGCTGAAGG ACAAGGCCTT CCGCGAGGCG 
GAGCGGCGCA TCCGCGAGTG CGCCAAGCTG CAGCGGAGGC ACCACGAACG CATGGAGCGG 
CGATACCGGC GCGAGCTGGC CGAGCGTTCC GACACCCTCA GCTTCTCCAG CCTCACGTCC 
AGCACCCTGA GCCGCCGGCT GCAGCATCTG GCGCTGGGCA GCCACCTGCC GTACTCTCAG 
GCCACGCTGC ACGGCACGGC CAGGGGCAAG ACCAAGATGC AGAAGAAGCT GGAGCGGCGC 
AAGCAGGGCG GCGAAGGCAC CTTCAAGGTC TCCGAGGATG GGCGCAAGAG CGCCCGCTCG 
CTCTCGGGCC TGCAGCTGGG CAGCGACGTG ATGTTCGTGC GCCAGGGCAC CTACGCCAAT 
CCCAAGGAGT GGGGCCGAGC CCCGCTCCGG GACATGTTCC TCTCGGACGA GGACAGCGTC 
TCCCGTGCCA CGCTGGCGGC CGAGCCTGCC CACTCGGAGG TCAGCACCGA CTCAGGCCAC 
GACTCCCTGT TTACCCGCCC CGGCCTGGGC ACCATGGTGT TCCGCAGAAA TTACTTGAGC 
AGTGGGCTGC ACGGACTGGG CCGCGAGGAT GGGGGTCTGG ATGGGGTGGG AGCGCCGCGG 
GGTCGGCTGC AGAGCTCCCC CAGCCTGGAC GATGACAGCC TGGGCAGTGC CAACAGCCTG 
CAGGACCGCA GCTGTGGGGA GGAGCTGCCC TGGGATGAGC TCGATTTAGG CTTGGACGAG 
GACCTGGAGC CCGAGACTAG CCCGCTGGAG ACCTTCCTGG CCTCTCTGCA CATGGAGGAC 
TTTGCCGCCC TCCTGCGGCA GGAGAAGATC GACCTCGAGG CTTTGATGCT GTGCTCTGAC 
CTCGACCTCC GCAGCATCAG CGTCCCACTG GGGCCCCGAA AGAAGATCTT GGGGGCCGTG 
AGGAGGCGGC GGCAGGCGAT GGAGCGCCCG CCGGCCCTGG AGGACACAGA GCTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011522598.1
CDS	473..1549
Translation	MAAMKGHMECVRYLDSIAAKQSSLNPKLVGKLKDKAFREAERRIRECAKLQRRHHERMERRYRRELAERSDTLSFSSLTSSTLSRRLQHLALGSHLPYSQATLHGTARGKTKMQKKLERRKQGGEGTFKVSEDGRKSARSLSGLQLGSDVMFVRQGTYANPKEWGRAPLRDMFLSDEDSVSRATLAAEPAHSEVSTDSGHDSLFTRPGLGTMVFRRNYLSSGLHGLGREDGGLDGVGAPRGRLQSSPSLDDDSLGSANSLQDRSCGEELPWDELDLGLDEDLEPETSPLETFLASLHMEDFAALLRQEKIDLEALMLCSDLDLRSISVPLGPRKKILGAVRRRRQAMERPPALEDTEL

Target ORF information:

RefSeq Version	XM_011524296.2
Organism	Homo sapiens(human)
Definition	Homo sapiens USH1 protein network component sans (USH1G), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011524296.2

ORF Insert Sequence:

ATGGCTGCCA TGAAGGGCCA CATGGAATGC GTGCGCTACC TGGACTCCAT CGCGGCCAAG 
CAGAGCAGCC TCAACCCCAA GCTGGTGGGT AAGCTGAAGG ACAAGGCCTT CCGCGAGGCG 
GAGCGGCGCA TCCGCGAGTG CGCCAAGCTG CAGCGGAGGC ACCACGAACG CATGGAGCGG 
CGATACCGGC GCGAGCTGGC CGAGCGTTCC GACACCCTCA GCTTCTCCAG CCTCACGTCC 
AGCACCCTGA GCCGCCGGCT GCAGCATCTG GCGCTGGGCA GCCACCTGCC GTACTCTCAG 
GCCACGCTGC ACGGCACGGC CAGGGGCAAG ACCAAGATGC AGAAGAAGCT GGAGCGGCGC 
AAGCAGGGCG GCGAAGGCAC CTTCAAGGTC TCCGAGGATG GGCGCAAGAG CGCCCGCTCG 
CTCTCGGGCC TGCAGCTGGG CAGCGACGTG ATGTTCGTGC GCCAGGGCAC CTACGCCAAT 
CCCAAGGAGT GGGGCCGAGC CCCGCTCCGG GACATGTTCC TCTCGGACGA GGACAGCGTC 
TCCCGTGCCA CGCTGGCGGC CGAGCCTGCC CACTCGGAGG TCAGCACCGA CTCAGGCCAC 
GACTCCCTGT TTACCCGCCC CGGCCTGGGC ACCATGGTGT TCCGCAGAAA TTACTTGAGC 
AGTGGGCTGC ACGGACTGGG CCGCGAGGAT GGGGGTCTGG ATGGGGTGGG AGCGCCGCGG 
GGTCGGCTGC AGAGCTCCCC CAGCCTGGAC GATGACAGCC TGGGCAGTGC CAACAGCCTG 
CAGGACCGCA GCTGTGGGGA GGAGCTGCCC TGGGATGAGC TCGATTTAGG CTTGGACGAG 
GACCTGGAGC CCGAGACTAG CCCGCTGGAG ACCTTCCTGG CCTCTCTGCA CATGGAGGAC 
TTTGCCGCCC TCCTGCGGCA GGAGAAGATC GACCTCGAGG CTTTGATGCT GTGCTCTGAC 
CTCGACCTCC GCAGCATCAG CGTCCCACTG GGGCCCCGAA AGAAGATCTT GGGGGCCGTG 
AGGAGGCGGC GGCAGGCGAT GGAGCGCCCG CCGGCCCTGG AGGACACAGA GCTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

USH1G ( XM_011524296.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011522598.1 Homo sapiens Usher syndrome 1G (autosomal recessive) (USH1G), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu23504
Clone ID Related Accession (Same CDS sequence)	XM_011524296.2 , XM_011524296.1 , NM_001282489.2 , NM_001282489.3
Accession Version	XM_011524296.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1077bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	Usher syndrome type-1G protein isoform X1
Comment

ATGGCTGCCA TGAAGGGCCA CATGGAATGC GTGCGCTACC TGGACTCCAT CGCGGCCAAG 
CAGAGCAGCC TCAACCCCAA GCTGGTGGGT AAGCTGAAGG ACAAGGCCTT CCGCGAGGCG 
GAGCGGCGCA TCCGCGAGTG CGCCAAGCTG CAGCGGAGGC ACCACGAACG CATGGAGCGG 
CGATACCGGC GCGAGCTGGC CGAGCGTTCC GACACCCTCA GCTTCTCCAG CCTCACGTCC 
AGCACCCTGA GCCGCCGGCT GCAGCATCTG GCGCTGGGCA GCCACCTGCC GTACTCTCAG 
GCCACGCTGC ACGGCACGGC CAGGGGCAAG ACCAAGATGC AGAAGAAGCT GGAGCGGCGC 
AAGCAGGGCG GCGAAGGCAC CTTCAAGGTC TCCGAGGATG GGCGCAAGAG CGCCCGCTCG 
CTCTCGGGCC TGCAGCTGGG CAGCGACGTG ATGTTCGTGC GCCAGGGCAC CTACGCCAAT 
CCCAAGGAGT GGGGCCGAGC CCCGCTCCGG GACATGTTCC TCTCGGACGA GGACAGCGTC 
TCCCGTGCCA CGCTGGCGGC CGAGCCTGCC CACTCGGAGG TCAGCACCGA CTCAGGCCAC 
GACTCCCTGT TTACCCGCCC CGGCCTGGGC ACCATGGTGT TCCGCAGAAA TTACTTGAGC 
AGTGGGCTGC ACGGACTGGG CCGCGAGGAT GGGGGTCTGG ATGGGGTGGG AGCGCCGCGG 
GGTCGGCTGC AGAGCTCCCC CAGCCTGGAC GATGACAGCC TGGGCAGTGC CAACAGCCTG 
CAGGACCGCA GCTGTGGGGA GGAGCTGCCC TGGGATGAGC TCGATTTAGG CTTGGACGAG 
GACCTGGAGC CCGAGACTAG CCCGCTGGAG ACCTTCCTGG CCTCTCTGCA CATGGAGGAC 
TTTGCCGCCC TCCTGCGGCA GGAGAAGATC GACCTCGAGG CTTTGATGCT GTGCTCTGAC 
CTCGACCTCC GCAGCATCAG CGTCCCACTG GGGCCCCGAA AGAAGATCTT GGGGGCCGTG 
AGGAGGCGGC GGCAGGCGAT GGAGCGCCCG CCGGCCCTGG AGGACACAGA GCTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011522598.1
Translation	MAAMKGHMECVRYLDSIAAKQSSLNPKLVGKLKDKAFREAERRIRECAKLQRRHHERMERRYRRELAERSDTLSFSSLTSSTLSRRLQHLALGSHLPYSQATLHGTARGKTKMQKKLERRKQGGEGTFKVSEDGRKSARSLSGLQLGSDVMFVRQGTYANPKEWGRAPLRDMFLSDEDSVSRATLAAEPAHSEVSTDSGHDSLFTRPGLGTMVFRRNYLSSGLHGLGREDGGLDGVGAPRGRLQSSPSLDDDSLGSANSLQDRSCGEELPWDELDLGLDEDLEPETSPLETFLASLHMEDFAALLRQEKIDLEALMLCSDLDLRSISVPLGPRKKILGAVRRRRQAMERPPALEDTEL

Target ORF information:

RefSeq Version	XM_011524296.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens Usher syndrome 1G (autosomal recessive) (USH1G), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011524296.1

ORF Insert Sequence:

ATGGCTGCCA TGAAGGGCCA CATGGAATGC GTGCGCTACC TGGACTCCAT CGCGGCCAAG 
CAGAGCAGCC TCAACCCCAA GCTGGTGGGT AAGCTGAAGG ACAAGGCCTT CCGCGAGGCG 
GAGCGGCGCA TCCGCGAGTG CGCCAAGCTG CAGCGGAGGC ACCACGAACG CATGGAGCGG 
CGATACCGGC GCGAGCTGGC CGAGCGTTCC GACACCCTCA GCTTCTCCAG CCTCACGTCC 
AGCACCCTGA GCCGCCGGCT GCAGCATCTG GCGCTGGGCA GCCACCTGCC GTACTCTCAG 
GCCACGCTGC ACGGCACGGC CAGGGGCAAG ACCAAGATGC AGAAGAAGCT GGAGCGGCGC 
AAGCAGGGCG GCGAAGGCAC CTTCAAGGTC TCCGAGGATG GGCGCAAGAG CGCCCGCTCG 
CTCTCGGGCC TGCAGCTGGG CAGCGACGTG ATGTTCGTGC GCCAGGGCAC CTACGCCAAT 
CCCAAGGAGT GGGGCCGAGC CCCGCTCCGG GACATGTTCC TCTCGGACGA GGACAGCGTC 
TCCCGTGCCA CGCTGGCGGC CGAGCCTGCC CACTCGGAGG TCAGCACCGA CTCAGGCCAC 
GACTCCCTGT TTACCCGCCC CGGCCTGGGC ACCATGGTGT TCCGCAGAAA TTACTTGAGC 
AGTGGGCTGC ACGGACTGGG CCGCGAGGAT GGGGGTCTGG ATGGGGTGGG AGCGCCGCGG 
GGTCGGCTGC AGAGCTCCCC CAGCCTGGAC GATGACAGCC TGGGCAGTGC CAACAGCCTG 
CAGGACCGCA GCTGTGGGGA GGAGCTGCCC TGGGATGAGC TCGATTTAGG CTTGGACGAG 
GACCTGGAGC CCGAGACTAG CCCGCTGGAG ACCTTCCTGG CCTCTCTGCA CATGGAGGAC 
TTTGCCGCCC TCCTGCGGCA GGAGAAGATC GACCTCGAGG CTTTGATGCT GTGCTCTGAC 
CTCGACCTCC GCAGCATCAG CGTCCCACTG GGGCCCCGAA AGAAGATCTT GGGGGCCGTG 
AGGAGGCGGC GGCAGGCGAT GGAGCGCCCG CCGGCCCTGG AGGACACAGA GCTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Myosin 7 and its adaptors link cadherins to actin.
Nature communications815864(2017 Jun)
Yu IM,Planelles-Herrero VJ,Sourigues Y,Moussaoui D,Sirkia H,Kikuti C,Stroebel D,Titus MA,Houdusse A

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Characterization of the ternary Usher syndrome SANS/ush2a/whirlin protein complex.
Human molecular genetics26(6)1157-1172(2017 03)
Sorusch N,Bau? K,Plutniok J,Samanta A,Knapp B,Nagel-Wolfrum K,Wolfrum U

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USH1G cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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