SFXN4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SFXN4
Entrez Gene ID	119559
Full Name	sideroflexin 4
Synonyms	BCRM1,COXPD18,SLC56A4
General protein information	Preferred Names sideroflexin 4 Names sideroflexin-4 breast cancer resistance marker 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10q26.11
Summary	This gene encodes a member of the sideroflexin family. The encoded protein is a transmembrane protein of the inner mitochondrial membrane, and is required for mitochondrial respiratory homeostasis and erythropoiesis. Mutations in this gene are associated with mitochondriopathy and macrocytic anemia. Alternatively spliced transcript variants have been found in this gene. [provided by RefSeq, Jan 2014].
Disorder MIM:	615564
Disorder Html:	Combined oxidative phosphorylation deficiency 18, 615578 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_024447793.1	XP_024303561.1	sideroflexin-4 isoform X2
NM_213649.1	NP_998814.1	sideroflexin-4
XM_005269525.5	XP_005269582.1	sideroflexin-4 isoform X1
NM_213649.2	NP_998814.1	sideroflexin-4
XM_005269525.4	XP_005269582.1	sideroflexin-4 isoform X1
XM_005269526.2	XP_005269583.1	sideroflexin-4 isoform X2
XM_011539282.2	XP_011537584.1	sideroflexin-4 isoform X2
XM_005269527.1	XP_005269584.1	sideroflexin-4 isoform X2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SFXN4	XP_535030.4
Gallus gallus (chicken)	SFXN4	XP_001234861.2
Danio rerio (zebrafish)	sfxn4	NP_001070130.1
	SFXN4	XP_001096920.2
Bos taurus (cattle)	SFXN4	NP_001030232.1
Xenopus tropicalis (tropical clawed frog)	LOC100487071	XP_002942800.2
Homo sapiens (human)	SFXN4	NP_998814.1
Pan troglodytes (chimpanzee)	SFXN4	XP_521661.3
Mus musculus (house mouse)	Sfxn4	NP_444428.3
Rattus norvegicus (Norway rat)	Sfxn4	NP_001101997.1

Gene Ontology
Bibliography

Related articles in PubMed

Macrocytic anemia and mitochondriopathy resulting from a defect in sideroflexin 4.
Hildick-Smith GJ, Cooney JD, Garone C, Kremer LS, Haack TB, Thon JN, Miyata N, Lieber DS, Calvo SE, Akman HO, Yien YY, Huston NC, Branco DS, Shah DI, Freedman ML, Koehler CM, Italiano JE Jr, Merkenschlager A, Beblo S, Strom TM, Meitinger T, Freisinger P, Donati MA, Prokisch H, Mootha VK, DiMauro S, Paw BH
American journal of human genetics93(5)906-14(2013 Nov)

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ
PloS one5(9)e12862(2010 Sep)

New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes and immunity11(3)232-8(2010 Apr)

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vri?ze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A
American journal of human genetics78(1)78-88(2006 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our findings establish mutations in SFXN4 as a cause of mitochondriopathy and macrocytic anemia.
Title: Macrocytic anemia and mitochondriopathy resulting from a defect in sideroflexin 4.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

Observational study of gene-disease association. (HuGE Navigator)
Title: New genetic associations detected in a host response study to hepatitis B vaccine.

Observational study of gene-disease association. (HuGE Navigator)
Title: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

we isolated a cDNA encoding a novel sideroflexin protein (SFXN4), which showed 59% identity and 71% similarity to mouse sideroflexin4.
Title: Molecular cloning and characterization of a novel human putative transmembrane protein homologous to mouse sideroflexin associated with sideroblastic anemia.

The following SFXN4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SFXN4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25980	NM_213649.1 Latest version!	Homo sapiens sideroflexin 4 (SFXN4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu44032	XM_005269525.5 Latest version!	Homo sapiens sideroflexin 4 (SFXN4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu44034	XM_005269527.1 Latest version!	Homo sapiens sideroflexin 4 (SFXN4), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu44034	XM_011539282.2 Latest version!	Homo sapiens sideroflexin 4 (SFXN4), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu44034	XM_005269526.2 Latest version!	Homo sapiens sideroflexin 4 (SFXN4), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu44034	XM_024447793.1 Latest version!	Homo sapiens sideroflexin 4 (SFXN4), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu108604	NM_213649.2 Latest version!	Homo sapiens sideroflexin 4 (SFXN4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu44032	XM_005269525.4	Homo sapiens sideroflexin 4 (SFXN4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SFXN4 ( NM_213649.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_998814.1 Homo sapiens sideroflexin 4 (SFXN4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu25980
Clone ID Related Accession (Same CDS sequence)	NM_213649.1
Accession Version	NM_213649.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Homo sapiens(human)
Product	sideroflexin-4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AW249181.1, BC063562.1 and CB306697.1. This sequence is a reference standard in the RefSeqGene project. On Mar 15, 2007 this sequence version replaced NM_213650.1. Transcript Variant: This variant (1) encodes a functional protein. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.405296.1, SRR1163658.389234.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCCTGG AACAGGAGGA GGAAACGCAA CCTGGGCGGC TCCTAGGACG CAGAGACGCC 
GTCCCCGCCT TCATTGAGCC CAACGTGCGC TTCTGGATCA CCGAGCGCCA ATCCTTTATT 
CGACGATTTC TTCAATGGAC AGAATTATTA GATCCTACAA ATGTGTTCAT TTCAGTTGAA 
AGTATAGAAA ACTCGAGGCA ACTATTGTGC ACAAATGAAG ATGTTTCCAG CCCTGCCTCG 
GCGGACCAAA GGATACAAGA AGCTTGGAAG CGGAGTCTTG CAACAGTGCA TCCCGACAGC 
AGCAACCTGA TCCCCAAGCT TTTTCGACCT GCAGCGTTCC TGCCTTTCAT GGCGCCCACG 
GTATTTTTGT CAATGACGCC ACTGAAAGGG ATCAAGTCCG TGATTTTACC TCAGGTTTTC 
CTCTGTGCCT ACATGGCAGC GTTCAACAGC ATCAATGGAA ACAGAAGTTA CACTTGTAAG 
CCACTAGAAA GATCATTACT AATGGCGGGA GCCGTTGCTT CTTCAACTTT CTTAGGAGTA 
ATCCCTCAGT TTGTCCAGAT GAAGTATGGC CTGACTGGCC CTTGGATTAA AAGACTCTTA 
CCTGTGATCT TCCTCGTGCA AGCCAGTGGA ATGAATGTCT ACATGTCCCG AAGTCTTGAA 
TCCATTAAGG GGATTGCGGT CATGGACAAG GAAGGCAATG TCCTGGGTCA TTCCAGAATT 
GCTGGGACAA AGGCTGTTAG AGAAACGCTA GCATCCAGAA TAGTGCTGTT TGGGACCTCA 
GCTCTGATTC CTGAAGTCTT CACCTACTTT TTTAAAAGGA CCCAGTATTT CAGGAAAAAC 
CCAGGGTCAT TGTGGATTTT GAAACTGTCT TGTACTGTCC TGGCAATGGG ACTGATGGTG 
CCATTTTCTT TTAGTATATT TCCACAGATT GGACAGATAC AGTACTGTAG TCTTGAAGAG 
AAAATTCAGT CTCCAACAGA AGAAACAGAA ATCTTTTATC ACAGAGGGGT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_998814.1
CDS	46..1059
Translation	MSLEQEEETQPGRLLGRRDAVPAFIEPNVRFWITERQSFIRRFLQWTELLDPTNVFISVESIENSRQLLCTNEDVSSPASADQRIQEAWKRSLATVHPDSSNLIPKLFRPAAFLPFMAPTVFLSMTPLKGIKSVILPQVFLCAYMAAFNSINGNRSYTCKPLERSLLMAGAVASSTFLGVIPQFVQMKYGLTGPWIKRLLPVIFLVQASGMNVYMSRSLESIKGIAVMDKEGNVLGHSRIAGTKAVRETLASRIVLFGTSALIPEVFTYFFKRTQYFRKNPGSLWILKLSCTVLAMGLMVPFSFSIFPQIGQIQYCSLEEKIQSPTEETEIFYHRGV

Target ORF information:

RefSeq Version	NM_213649.1
Organism	Homo sapiens(human)
Definition	Homo sapiens sideroflexin 4 (SFXN4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_213649.1

ORF Insert Sequence:

ATGTCCCTGG AACAGGAGGA GGAAACGCAA CCTGGGCGGC TCCTAGGACG CAGAGACGCC 
GTCCCCGCCT TCATTGAGCC CAACGTGCGC TTCTGGATCA CCGAGCGCCA ATCCTTTATT 
CGACGATTTC TTCAATGGAC AGAATTATTA GATCCTACAA ATGTGTTCAT TTCAGTTGAA 
AGTATAGAAA ACTCGAGGCA ACTATTGTGC ACAAATGAAG ATGTTTCCAG CCCTGCCTCG 
GCGGACCAAA GGATACAAGA AGCTTGGAAG CGGAGTCTTG CAACAGTGCA TCCCGACAGC 
AGCAACCTGA TCCCCAAGCT TTTTCGACCT GCAGCGTTCC TGCCTTTCAT GGCGCCCACG 
GTATTTTTGT CAATGACGCC ACTGAAAGGG ATCAAGTCCG TGATTTTACC TCAGGTTTTC 
CTCTGTGCCT ACATGGCAGC GTTCAACAGC ATCAATGGAA ACAGAAGTTA CACTTGTAAG 
CCACTAGAAA GATCATTACT AATGGCGGGA GCCGTTGCTT CTTCAACTTT CTTAGGAGTA 
ATCCCTCAGT TTGTCCAGAT GAAGTATGGC CTGACTGGCC CTTGGATTAA AAGACTCTTA 
CCTGTGATCT TCCTCGTGCA AGCCAGTGGA ATGAATGTCT ACATGTCCCG AAGTCTTGAA 
TCCATTAAGG GGATTGCGGT CATGGACAAG GAAGGCAATG TCCTGGGTCA TTCCAGAATT 
GCTGGGACAA AGGCTGTTAG AGAAACGCTA GCATCCAGAA TAGTGCTGTT TGGGACCTCA 
GCTCTGATTC CTGAAGTCTT CACCTACTTT TTTAAAAGGA CCCAGTATTT CAGGAAAAAC 
CCAGGGTCAT TGTGGATTTT GAAACTGTCT TGTACTGTCC TGGCAATGGG ACTGATGGTG 
CCATTTTCTT TTAGTATATT TCCACAGATT GGACAGATAC AGTACTGTAG TCTTGAAGAG 
AAAATTCAGT CTCCAACAGA AGAAACAGAA ATCTTTTATC ACAGAGGGGT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SFXN4 ( XM_005269525.5 ) cDNA ORF clone, Homo sapiens(human) -> XP_005269582.1 Homo sapiens sideroflexin 4 (SFXN4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu44032
Clone ID Related Accession (Same CDS sequence)	XM_005269525.5 , XM_005269525.4
Accession Version	XM_005269525.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	sideroflexin-4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005269525.4. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCCTGG AACAGGAGGA GGAAACGCAA CCTGGGCGGC TCCTAGGACG CAGAGACGCC 
GTCCCCGCCT TCATTGAGCC CAACGTGCGC TTCTGGATCA CCGAGCGCCA ATCCTTTATT 
CGACGATTTC TTCAATGGAC AGAATTATTA GATCCTACAA ATGTGTTCAT TTCAGTTGAA 
AGTATAGAAA ACTCGAGGCA ACTATTGTGC ACAAATGAAG ATGTTTCCAG CCCTGCCTCG 
GCGGACCAAA GGGCAACAGT GCATCCCGAC AGCAGCAACC TGATCCCCAA GCTTTTTCGA 
CCTGCAGCGT TCCTGCCTTT CATGGCACCC ACGGTATTTT TGTCAATGAC GCCACTGAAA 
GGGATCAAGT CCGTGATTTT ACCTCAGGTT TTCCTCTGTG CCTACATGGC AGCGTTCAAC 
AGCATCAATG GAAACAGAAG TTACACTTGT AAGCCACTAG AAAGATCATT ACTAATGGCG 
GGAGCCGTTG CTTCTTCAAC TTTCTTAGGA GTAATCCCTC AGTTTGTCCA GATGAAGTAT 
GGCCTGACTG GCCCTTGGAT TAAAAGACTC TTACCTGTGA TCTTCCTCGT GCAAGCCAGT 
GGAATGAATG TCTACATGTC CCGAAGTCTT GAATCCATTA AGGGGATTGC GGTCATGGAC 
AAGGAAGGCA ATGTCCTGGG TCATTCCAGA ATTGCTGGGA CAAAGGCTGT TAGAGAAACG 
CTAGCATCCA GAATAGTGCT GTTTGGGACC TCAGCTCTGA TTCCTGAAGT CTTCACCTAC 
TTTTTTAAAA GGACCCAGTA TTTCAGGAAA AACCCAGGGT CATTGTGGAT TTTGAAACTG 
TCTTGTACTG TCCTGGCAAT GGGACTGATG GTGCCATTTT CTTTTAGTAT ATTTCCACAG 
ATTGGACAGA TACAGTACTG TAGTCTTGAA GAGAAAATTC AGTCTCCAAC AGAAGAAACA 
GAAATCTTTT ATCACAGAGG GGTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005269582.1
CDS	40..1026
Translation	MSLEQEEETQPGRLLGRRDAVPAFIEPNVRFWITERQSFIRRFLQWTELLDPTNVFISVESIENSRQLLCTNEDVSSPASADQRATVHPDSSNLIPKLFRPAAFLPFMAPTVFLSMTPLKGIKSVILPQVFLCAYMAAFNSINGNRSYTCKPLERSLLMAGAVASSTFLGVIPQFVQMKYGLTGPWIKRLLPVIFLVQASGMNVYMSRSLESIKGIAVMDKEGNVLGHSRIAGTKAVRETLASRIVLFGTSALIPEVFTYFFKRTQYFRKNPGSLWILKLSCTVLAMGLMVPFSFSIFPQIGQIQYCSLEEKIQSPTEETEIFYHRGV

Target ORF information:

RefSeq Version	XM_005269525.5
Organism	Homo sapiens(human)
Definition	Homo sapiens sideroflexin 4 (SFXN4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005269525.5

ORF Insert Sequence:

ATGTCCCTGG AACAGGAGGA GGAAACGCAA CCTGGGCGGC TCCTAGGACG CAGAGACGCC 
GTCCCCGCCT TCATTGAGCC CAACGTGCGC TTCTGGATCA CCGAGCGCCA ATCCTTTATT 
CGACGATTTC TTCAATGGAC AGAATTATTA GATCCTACAA ATGTGTTCAT TTCAGTTGAA 
AGTATAGAAA ACTCGAGGCA ACTATTGTGC ACAAATGAAG ATGTTTCCAG CCCTGCCTCG 
GCGGACCAAA GGGCAACAGT GCATCCCGAC AGCAGCAACC TGATCCCCAA GCTTTTTCGA 
CCTGCAGCGT TCCTGCCTTT CATGGCACCC ACGGTATTTT TGTCAATGAC GCCACTGAAA 
GGGATCAAGT CCGTGATTTT ACCTCAGGTT TTCCTCTGTG CCTACATGGC AGCGTTCAAC 
AGCATCAATG GAAACAGAAG TTACACTTGT AAGCCACTAG AAAGATCATT ACTAATGGCG 
GGAGCCGTTG CTTCTTCAAC TTTCTTAGGA GTAATCCCTC AGTTTGTCCA GATGAAGTAT 
GGCCTGACTG GCCCTTGGAT TAAAAGACTC TTACCTGTGA TCTTCCTCGT GCAAGCCAGT 
GGAATGAATG TCTACATGTC CCGAAGTCTT GAATCCATTA AGGGGATTGC GGTCATGGAC 
AAGGAAGGCA ATGTCCTGGG TCATTCCAGA ATTGCTGGGA CAAAGGCTGT TAGAGAAACG 
CTAGCATCCA GAATAGTGCT GTTTGGGACC TCAGCTCTGA TTCCTGAAGT CTTCACCTAC 
TTTTTTAAAA GGACCCAGTA TTTCAGGAAA AACCCAGGGT CATTGTGGAT TTTGAAACTG 
TCTTGTACTG TCCTGGCAAT GGGACTGATG GTGCCATTTT CTTTTAGTAT ATTTCCACAG 
ATTGGACAGA TACAGTACTG TAGTCTTGAA GAGAAAATTC AGTCTCCAAC AGAAGAAACA 
GAAATCTTTT ATCACAGAGG GGTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SFXN4 ( XM_005269525.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005269582.1 Homo sapiens sideroflexin 4 (SFXN4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu44032
Clone ID Related Accession (Same CDS sequence)	XM_005269525.5 , XM_005269525.4
Accession Version	XM_005269525.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	sideroflexin-4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005269525.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCCTGG AACAGGAGGA GGAAACGCAA CCTGGGCGGC TCCTAGGACG CAGAGACGCC 
GTCCCCGCCT TCATTGAGCC CAACGTGCGC TTCTGGATCA CCGAGCGCCA ATCCTTTATT 
CGACGATTTC TTCAATGGAC AGAATTATTA GATCCTACAA ATGTGTTCAT TTCAGTTGAA 
AGTATAGAAA ACTCGAGGCA ACTATTGTGC ACAAATGAAG ATGTTTCCAG CCCTGCCTCG 
GCGGACCAAA GGGCAACAGT GCATCCCGAC AGCAGCAACC TGATCCCCAA GCTTTTTCGA 
CCTGCAGCGT TCCTGCCTTT CATGGCACCC ACGGTATTTT TGTCAATGAC GCCACTGAAA 
GGGATCAAGT CCGTGATTTT ACCTCAGGTT TTCCTCTGTG CCTACATGGC AGCGTTCAAC 
AGCATCAATG GAAACAGAAG TTACACTTGT AAGCCACTAG AAAGATCATT ACTAATGGCG 
GGAGCCGTTG CTTCTTCAAC TTTCTTAGGA GTAATCCCTC AGTTTGTCCA GATGAAGTAT 
GGCCTGACTG GCCCTTGGAT TAAAAGACTC TTACCTGTGA TCTTCCTCGT GCAAGCCAGT 
GGAATGAATG TCTACATGTC CCGAAGTCTT GAATCCATTA AGGGGATTGC GGTCATGGAC 
AAGGAAGGCA ATGTCCTGGG TCATTCCAGA ATTGCTGGGA CAAAGGCTGT TAGAGAAACG 
CTAGCATCCA GAATAGTGCT GTTTGGGACC TCAGCTCTGA TTCCTGAAGT CTTCACCTAC 
TTTTTTAAAA GGACCCAGTA TTTCAGGAAA AACCCAGGGT CATTGTGGAT TTTGAAACTG 
TCTTGTACTG TCCTGGCAAT GGGACTGATG GTGCCATTTT CTTTTAGTAT ATTTCCACAG 
ATTGGACAGA TACAGTACTG TAGTCTTGAA GAGAAAATTC AGTCTCCAAC AGAAGAAACA 
GAAATCTTTT ATCACAGAGG GGTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005269582.1
CDS	5..991
Translation	MSLEQEEETQPGRLLGRRDAVPAFIEPNVRFWITERQSFIRRFLQWTELLDPTNVFISVESIENSRQLLCTNEDVSSPASADQRATVHPDSSNLIPKLFRPAAFLPFMAPTVFLSMTPLKGIKSVILPQVFLCAYMAAFNSINGNRSYTCKPLERSLLMAGAVASSTFLGVIPQFVQMKYGLTGPWIKRLLPVIFLVQASGMNVYMSRSLESIKGIAVMDKEGNVLGHSRIAGTKAVRETLASRIVLFGTSALIPEVFTYFFKRTQYFRKNPGSLWILKLSCTVLAMGLMVPFSFSIFPQIGQIQYCSLEEKIQSPTEETEIFYHRGV

Target ORF information:

RefSeq Version	XM_005269525.4
Organism	Homo sapiens(human)
Definition	Homo sapiens sideroflexin 4 (SFXN4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005269525.4

ORF Insert Sequence:

ATGTCCCTGG AACAGGAGGA GGAAACGCAA CCTGGGCGGC TCCTAGGACG CAGAGACGCC 
GTCCCCGCCT TCATTGAGCC CAACGTGCGC TTCTGGATCA CCGAGCGCCA ATCCTTTATT 
CGACGATTTC TTCAATGGAC AGAATTATTA GATCCTACAA ATGTGTTCAT TTCAGTTGAA 
AGTATAGAAA ACTCGAGGCA ACTATTGTGC ACAAATGAAG ATGTTTCCAG CCCTGCCTCG 
GCGGACCAAA GGGCAACAGT GCATCCCGAC AGCAGCAACC TGATCCCCAA GCTTTTTCGA 
CCTGCAGCGT TCCTGCCTTT CATGGCACCC ACGGTATTTT TGTCAATGAC GCCACTGAAA 
GGGATCAAGT CCGTGATTTT ACCTCAGGTT TTCCTCTGTG CCTACATGGC AGCGTTCAAC 
AGCATCAATG GAAACAGAAG TTACACTTGT AAGCCACTAG AAAGATCATT ACTAATGGCG 
GGAGCCGTTG CTTCTTCAAC TTTCTTAGGA GTAATCCCTC AGTTTGTCCA GATGAAGTAT 
GGCCTGACTG GCCCTTGGAT TAAAAGACTC TTACCTGTGA TCTTCCTCGT GCAAGCCAGT 
GGAATGAATG TCTACATGTC CCGAAGTCTT GAATCCATTA AGGGGATTGC GGTCATGGAC 
AAGGAAGGCA ATGTCCTGGG TCATTCCAGA ATTGCTGGGA CAAAGGCTGT TAGAGAAACG 
CTAGCATCCA GAATAGTGCT GTTTGGGACC TCAGCTCTGA TTCCTGAAGT CTTCACCTAC 
TTTTTTAAAA GGACCCAGTA TTTCAGGAAA AACCCAGGGT CATTGTGGAT TTTGAAACTG 
TCTTGTACTG TCCTGGCAAT GGGACTGATG GTGCCATTTT CTTTTAGTAT ATTTCCACAG 
ATTGGACAGA TACAGTACTG TAGTCTTGAA GAGAAAATTC AGTCTCCAAC AGAAGAAACA 
GAAATCTTTT ATCACAGAGG GGTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SFXN4 ( XM_024447793.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024303561.1 Homo sapiens sideroflexin 4 (SFXN4), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OHu44034
Clone ID Related Accession (Same CDS sequence)	XM_024447793.1 , XM_005269526.2 , XM_011539282.2 , XM_005269527.1
Accession Version	XM_024447793.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 666bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	sideroflexin-4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCACCCA CGGTATTTTT GTCAATGACG CCACTGAAAG GGATCAAGTC CGTGATTTTA 
CCTCAGGTTT TCCTCTGTGC CTACATGGCA GCGTTCAACA GCATCAATGG AAACAGAAGT 
TACACTTGTA AGCCACTAGA AAGATCATTA CTAATGGCGG GAGCCGTTGC TTCTTCAACT 
TTCTTAGGAG TAATCCCTCA GTTTGTCCAG ATGAAGTATG GCCTGACTGG CCCTTGGATT 
AAAAGACTCT TACCTGTGAT CTTCCTCGTG CAAGCCAGTG GAATGAATGT CTACATGTCC 
CGAAGTCTTG AATCCATTAA GGGGATTGCG GTCATGGACA AGGAAGGCAA TGTCCTGGGT 
CATTCCAGAA TTGCTGGGAC AAAGGCTGTT AGAGAAACGC TAGCATCCAG AATAGTGCTG 
TTTGGGACCT CAGCTCTGAT TCCTGAAGTC TTCACCTACT TTTTTAAAAG GACCCAGTAT 
TTCAGGAAAA ACCCAGGGTC ATTGTGGATT TTGAAACTGT CTTGTACTGT CCTGGCAATG 
GGACTGATGG TGCCATTTTC TTTTAGTATA TTTCCACAGA TTGGACAGAT ACAGTACTGT 
AGTCTTGAAG AGAAAATTCA GTCTCCAACA GAAGAAACAG AAATCTTTTA TCACAGAGGG 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024303561.1
CDS	1958..2623
Translation	MAPTVFLSMTPLKGIKSVILPQVFLCAYMAAFNSINGNRSYTCKPLERSLLMAGAVASSTFLGVIPQFVQMKYGLTGPWIKRLLPVIFLVQASGMNVYMSRSLESIKGIAVMDKEGNVLGHSRIAGTKAVRETLASRIVLFGTSALIPEVFTYFFKRTQYFRKNPGSLWILKLSCTVLAMGLMVPFSFSIFPQIGQIQYCSLEEKIQSPTEETEIFYHRGV

Target ORF information:

RefSeq Version	XM_024447793.1
Organism	Homo sapiens(human)
Definition	Homo sapiens sideroflexin 4 (SFXN4), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024447793.1

ORF Insert Sequence:

ATGGCACCCA CGGTATTTTT GTCAATGACG CCACTGAAAG GGATCAAGTC CGTGATTTTA 
CCTCAGGTTT TCCTCTGTGC CTACATGGCA GCGTTCAACA GCATCAATGG AAACAGAAGT 
TACACTTGTA AGCCACTAGA AAGATCATTA CTAATGGCGG GAGCCGTTGC TTCTTCAACT 
TTCTTAGGAG TAATCCCTCA GTTTGTCCAG ATGAAGTATG GCCTGACTGG CCCTTGGATT 
AAAAGACTCT TACCTGTGAT CTTCCTCGTG CAAGCCAGTG GAATGAATGT CTACATGTCC 
CGAAGTCTTG AATCCATTAA GGGGATTGCG GTCATGGACA AGGAAGGCAA TGTCCTGGGT 
CATTCCAGAA TTGCTGGGAC AAAGGCTGTT AGAGAAACGC TAGCATCCAG AATAGTGCTG 
TTTGGGACCT CAGCTCTGAT TCCTGAAGTC TTCACCTACT TTTTTAAAAG GACCCAGTAT 
TTCAGGAAAA ACCCAGGGTC ATTGTGGATT TTGAAACTGT CTTGTACTGT CCTGGCAATG 
GGACTGATGG TGCCATTTTC TTTTAGTATA TTTCCACAGA TTGGACAGAT ACAGTACTGT 
AGTCTTGAAG AGAAAATTCA GTCTCCAACA GAAGAAACAG AAATCTTTTA TCACAGAGGG 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SFXN4 ( XM_005269526.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005269583.1 Homo sapiens sideroflexin 4 (SFXN4), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu44034
Clone ID Related Accession (Same CDS sequence)	XM_024447793.1 , XM_005269526.2 , XM_011539282.2 , XM_005269527.1
Accession Version	XM_005269526.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 666bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	sideroflexin-4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005269526.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCACCCA CGGTATTTTT GTCAATGACG CCACTGAAAG GGATCAAGTC CGTGATTTTA 
CCTCAGGTTT TCCTCTGTGC CTACATGGCA GCGTTCAACA GCATCAATGG AAACAGAAGT 
TACACTTGTA AGCCACTAGA AAGATCATTA CTAATGGCGG GAGCCGTTGC TTCTTCAACT 
TTCTTAGGAG TAATCCCTCA GTTTGTCCAG ATGAAGTATG GCCTGACTGG CCCTTGGATT 
AAAAGACTCT TACCTGTGAT CTTCCTCGTG CAAGCCAGTG GAATGAATGT CTACATGTCC 
CGAAGTCTTG AATCCATTAA GGGGATTGCG GTCATGGACA AGGAAGGCAA TGTCCTGGGT 
CATTCCAGAA TTGCTGGGAC AAAGGCTGTT AGAGAAACGC TAGCATCCAG AATAGTGCTG 
TTTGGGACCT CAGCTCTGAT TCCTGAAGTC TTCACCTACT TTTTTAAAAG GACCCAGTAT 
TTCAGGAAAA ACCCAGGGTC ATTGTGGATT TTGAAACTGT CTTGTACTGT CCTGGCAATG 
GGACTGATGG TGCCATTTTC TTTTAGTATA TTTCCACAGA TTGGACAGAT ACAGTACTGT 
AGTCTTGAAG AGAAAATTCA GTCTCCAACA GAAGAAACAG AAATCTTTTA TCACAGAGGG 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005269583.1
CDS	630..1295
Translation	MAPTVFLSMTPLKGIKSVILPQVFLCAYMAAFNSINGNRSYTCKPLERSLLMAGAVASSTFLGVIPQFVQMKYGLTGPWIKRLLPVIFLVQASGMNVYMSRSLESIKGIAVMDKEGNVLGHSRIAGTKAVRETLASRIVLFGTSALIPEVFTYFFKRTQYFRKNPGSLWILKLSCTVLAMGLMVPFSFSIFPQIGQIQYCSLEEKIQSPTEETEIFYHRGV

Target ORF information:

RefSeq Version	XM_005269526.2
Organism	Homo sapiens(human)
Definition	Homo sapiens sideroflexin 4 (SFXN4), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005269526.2

ORF Insert Sequence:

ATGGCACCCA CGGTATTTTT GTCAATGACG CCACTGAAAG GGATCAAGTC CGTGATTTTA 
CCTCAGGTTT TCCTCTGTGC CTACATGGCA GCGTTCAACA GCATCAATGG AAACAGAAGT 
TACACTTGTA AGCCACTAGA AAGATCATTA CTAATGGCGG GAGCCGTTGC TTCTTCAACT 
TTCTTAGGAG TAATCCCTCA GTTTGTCCAG ATGAAGTATG GCCTGACTGG CCCTTGGATT 
AAAAGACTCT TACCTGTGAT CTTCCTCGTG CAAGCCAGTG GAATGAATGT CTACATGTCC 
CGAAGTCTTG AATCCATTAA GGGGATTGCG GTCATGGACA AGGAAGGCAA TGTCCTGGGT 
CATTCCAGAA TTGCTGGGAC AAAGGCTGTT AGAGAAACGC TAGCATCCAG AATAGTGCTG 
TTTGGGACCT CAGCTCTGAT TCCTGAAGTC TTCACCTACT TTTTTAAAAG GACCCAGTAT 
TTCAGGAAAA ACCCAGGGTC ATTGTGGATT TTGAAACTGT CTTGTACTGT CCTGGCAATG 
GGACTGATGG TGCCATTTTC TTTTAGTATA TTTCCACAGA TTGGACAGAT ACAGTACTGT 
AGTCTTGAAG AGAAAATTCA GTCTCCAACA GAAGAAACAG AAATCTTTTA TCACAGAGGG 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SFXN4 ( XM_011539282.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011537584.1 Homo sapiens sideroflexin 4 (SFXN4), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu44034
Clone ID Related Accession (Same CDS sequence)	XM_024447793.1 , XM_005269526.2 , XM_011539282.2 , XM_005269527.1
Accession Version	XM_011539282.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 666bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	sideroflexin-4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011539282.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCACCCA CGGTATTTTT GTCAATGACG CCACTGAAAG GGATCAAGTC CGTGATTTTA 
CCTCAGGTTT TCCTCTGTGC CTACATGGCA GCGTTCAACA GCATCAATGG AAACAGAAGT 
TACACTTGTA AGCCACTAGA AAGATCATTA CTAATGGCGG GAGCCGTTGC TTCTTCAACT 
TTCTTAGGAG TAATCCCTCA GTTTGTCCAG ATGAAGTATG GCCTGACTGG CCCTTGGATT 
AAAAGACTCT TACCTGTGAT CTTCCTCGTG CAAGCCAGTG GAATGAATGT CTACATGTCC 
CGAAGTCTTG AATCCATTAA GGGGATTGCG GTCATGGACA AGGAAGGCAA TGTCCTGGGT 
CATTCCAGAA TTGCTGGGAC AAAGGCTGTT AGAGAAACGC TAGCATCCAG AATAGTGCTG 
TTTGGGACCT CAGCTCTGAT TCCTGAAGTC TTCACCTACT TTTTTAAAAG GACCCAGTAT 
TTCAGGAAAA ACCCAGGGTC ATTGTGGATT TTGAAACTGT CTTGTACTGT CCTGGCAATG 
GGACTGATGG TGCCATTTTC TTTTAGTATA TTTCCACAGA TTGGACAGAT ACAGTACTGT 
AGTCTTGAAG AGAAAATTCA GTCTCCAACA GAAGAAACAG AAATCTTTTA TCACAGAGGG 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011537584.1
CDS	522..1187
Translation	MAPTVFLSMTPLKGIKSVILPQVFLCAYMAAFNSINGNRSYTCKPLERSLLMAGAVASSTFLGVIPQFVQMKYGLTGPWIKRLLPVIFLVQASGMNVYMSRSLESIKGIAVMDKEGNVLGHSRIAGTKAVRETLASRIVLFGTSALIPEVFTYFFKRTQYFRKNPGSLWILKLSCTVLAMGLMVPFSFSIFPQIGQIQYCSLEEKIQSPTEETEIFYHRGV

Target ORF information:

RefSeq Version	XM_011539282.2
Organism	Homo sapiens(human)
Definition	Homo sapiens sideroflexin 4 (SFXN4), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011539282.2

ORF Insert Sequence:

ATGGCACCCA CGGTATTTTT GTCAATGACG CCACTGAAAG GGATCAAGTC CGTGATTTTA 
CCTCAGGTTT TCCTCTGTGC CTACATGGCA GCGTTCAACA GCATCAATGG AAACAGAAGT 
TACACTTGTA AGCCACTAGA AAGATCATTA CTAATGGCGG GAGCCGTTGC TTCTTCAACT 
TTCTTAGGAG TAATCCCTCA GTTTGTCCAG ATGAAGTATG GCCTGACTGG CCCTTGGATT 
AAAAGACTCT TACCTGTGAT CTTCCTCGTG CAAGCCAGTG GAATGAATGT CTACATGTCC 
CGAAGTCTTG AATCCATTAA GGGGATTGCG GTCATGGACA AGGAAGGCAA TGTCCTGGGT 
CATTCCAGAA TTGCTGGGAC AAAGGCTGTT AGAGAAACGC TAGCATCCAG AATAGTGCTG 
TTTGGGACCT CAGCTCTGAT TCCTGAAGTC TTCACCTACT TTTTTAAAAG GACCCAGTAT 
TTCAGGAAAA ACCCAGGGTC ATTGTGGATT TTGAAACTGT CTTGTACTGT CCTGGCAATG 
GGACTGATGG TGCCATTTTC TTTTAGTATA TTTCCACAGA TTGGACAGAT ACAGTACTGT 
AGTCTTGAAG AGAAAATTCA GTCTCCAACA GAAGAAACAG AAATCTTTTA TCACAGAGGG 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SFXN4 ( XM_005269527.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005269584.1 Homo sapiens sideroflexin 4 (SFXN4), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu44034
Clone ID Related Accession (Same CDS sequence)	XM_024447793.1 , XM_005269526.2 , XM_011539282.2 , XM_005269527.1
Accession Version	XM_005269527.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 666bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	sideroflexin-4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCACCCA CGGTATTTTT GTCAATGACG CCACTGAAAG GGATCAAGTC CGTGATTTTA 
CCTCAGGTTT TCCTCTGTGC CTACATGGCA GCGTTCAACA GCATCAATGG AAACAGAAGT 
TACACTTGTA AGCCACTAGA AAGATCATTA CTAATGGCGG GAGCCGTTGC TTCTTCAACT 
TTCTTAGGAG TAATCCCTCA GTTTGTCCAG ATGAAGTATG GCCTGACTGG CCCTTGGATT 
AAAAGACTCT TACCTGTGAT CTTCCTCGTG CAAGCCAGTG GAATGAATGT CTACATGTCC 
CGAAGTCTTG AATCCATTAA GGGGATTGCG GTCATGGACA AGGAAGGCAA TGTCCTGGGT 
CATTCCAGAA TTGCTGGGAC AAAGGCTGTT AGAGAAACGC TAGCATCCAG AATAGTGCTG 
TTTGGGACCT CAGCTCTGAT TCCTGAAGTC TTCACCTACT TTTTTAAAAG GACCCAGTAT 
TTCAGGAAAA ACCCAGGGTC ATTGTGGATT TTGAAACTGT CTTGTACTGT CCTGGCAATG 
GGACTGATGG TGCCATTTTC TTTTAGTATA TTTCCACAGA TTGGACAGAT ACAGTACTGT 
AGTCTTGAAG AGAAAATTCA GTCTCCAACA GAAGAAACAG AAATCTTTTA TCACAGAGGG 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005269584.1
CDS	552..1217
Translation	MAPTVFLSMTPLKGIKSVILPQVFLCAYMAAFNSINGNRSYTCKPLERSLLMAGAVASSTFLGVIPQFVQMKYGLTGPWIKRLLPVIFLVQASGMNVYMSRSLESIKGIAVMDKEGNVLGHSRIAGTKAVRETLASRIVLFGTSALIPEVFTYFFKRTQYFRKNPGSLWILKLSCTVLAMGLMVPFSFSIFPQIGQIQYCSLEEKIQSPTEETEIFYHRGV

Target ORF information:

RefSeq Version	XM_005269527.1
Organism	Homo sapiens(human)
Definition	Homo sapiens sideroflexin 4 (SFXN4), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005269527.1

ORF Insert Sequence:

ATGGCACCCA CGGTATTTTT GTCAATGACG CCACTGAAAG GGATCAAGTC CGTGATTTTA 
CCTCAGGTTT TCCTCTGTGC CTACATGGCA GCGTTCAACA GCATCAATGG AAACAGAAGT 
TACACTTGTA AGCCACTAGA AAGATCATTA CTAATGGCGG GAGCCGTTGC TTCTTCAACT 
TTCTTAGGAG TAATCCCTCA GTTTGTCCAG ATGAAGTATG GCCTGACTGG CCCTTGGATT 
AAAAGACTCT TACCTGTGAT CTTCCTCGTG CAAGCCAGTG GAATGAATGT CTACATGTCC 
CGAAGTCTTG AATCCATTAA GGGGATTGCG GTCATGGACA AGGAAGGCAA TGTCCTGGGT 
CATTCCAGAA TTGCTGGGAC AAAGGCTGTT AGAGAAACGC TAGCATCCAG AATAGTGCTG 
TTTGGGACCT CAGCTCTGAT TCCTGAAGTC TTCACCTACT TTTTTAAAAG GACCCAGTAT 
TTCAGGAAAA ACCCAGGGTC ATTGTGGATT TTGAAACTGT CTTGTACTGT CCTGGCAATG 
GGACTGATGG TGCCATTTTC TTTTAGTATA TTTCCACAGA TTGGACAGAT ACAGTACTGT 
AGTCTTGAAG AGAAAATTCA GTCTCCAACA GAAGAAACAG AAATCTTTTA TCACAGAGGG 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SFXN4 ( NM_213649.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_998814.1 Homo sapiens sideroflexin 4 (SFXN4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu108604
Clone ID Related Accession (Same CDS sequence)	NM_213649.2
Accession Version	NM_213649.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-18
Organism	Homo sapiens(human)
Product	sideroflexin-4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL355861.19 and AL355598.26. On May 17, 2019 this sequence version replaced NM_213649.1. Transcript Variant: This variant (1) encodes a functional protein. ##Evidence-Data-START## Transcript exon combination :: SRR5189661.89585.1, SRR5189658.19920.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000355697.7/ ENSP00000347924.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCCCTGG AACAGGAGGA GGAAACGCAA CCTGGGCGGC TCCTAGGACG CAGAGACGCC 
GTCCCCGCCT TCATTGAGCC CAACGTGCGC TTCTGGATCA CCGAGCGCCA ATCCTTTATT 
CGACGATTTC TTCAATGGAC AGAATTATTA GATCCTACAA ATGTGTTCAT TTCAGTTGAA 
AGTATAGAAA ACTCGAGGCA ACTATTGTGC ACAAATGAAG ATGTTTCCAG CCCTGCCTCG 
GCGGACCAAA GGATACAAGA AGCTTGGAAG CGGAGTCTTG CAACAGTGCA TCCCGACAGC 
AGCAACCTGA TCCCCAAGCT TTTTCGACCT GCAGCGTTCC TGCCTTTCAT GGCACCCACG 
GTATTTTTGT CAATGACGCC ACTGAAAGGG ATCAAGTCCG TGATTTTACC TCAGGTTTTC 
CTCTGTGCCT ACATGGCAGC GTTCAACAGC ATCAATGGAA ACAGAAGTTA CACTTGTAAG 
CCACTAGAAA GATCATTACT AATGGCGGGA GCCGTTGCTT CTTCAACTTT CTTAGGAGTA 
ATCCCTCAGT TTGTCCAGAT GAAGTATGGC CTGACTGGCC CTTGGATTAA AAGACTCTTA 
CCTGTGATCT TCCTCGTGCA AGCCAGTGGA ATGAATGTCT ACATGTCCCG AAGTCTTGAA 
TCCATTAAGG GGATTGCGGT CATGGACAAG GAAGGCAATG TCCTGGGTCA TTCCAGAATT 
GCTGGGACAA AGGCTGTTAG AGAAACGCTA GCATCCAGAA TAGTGCTGTT TGGGACCTCA 
GCTCTGATTC CTGAAGTCTT CACCTACTTT TTTAAAAGGA CCCAGTATTT CAGGAAAAAC 
CCAGGGTCAT TGTGGATTTT GAAACTGTCT TGTACTGTCC TGGCAATGGG ACTGATGGTG 
CCATTTTCTT TTAGTATATT TCCACAGATT GGACAGATAC AGTACTGTAG TCTTGAAGAG 
AAAATTCAGT CTCCAACAGA AGAAACAGAA ATCTTTTATC ACAGAGGGGT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_998814.1
CDS	68..1081
Translation	MSLEQEEETQPGRLLGRRDAVPAFIEPNVRFWITERQSFIRRFLQWTELLDPTNVFISVESIENSRQLLCTNEDVSSPASADQRIQEAWKRSLATVHPDSSNLIPKLFRPAAFLPFMAPTVFLSMTPLKGIKSVILPQVFLCAYMAAFNSINGNRSYTCKPLERSLLMAGAVASSTFLGVIPQFVQMKYGLTGPWIKRLLPVIFLVQASGMNVYMSRSLESIKGIAVMDKEGNVLGHSRIAGTKAVRETLASRIVLFGTSALIPEVFTYFFKRTQYFRKNPGSLWILKLSCTVLAMGLMVPFSFSIFPQIGQIQYCSLEEKIQSPTEETEIFYHRGV

Target ORF information:

RefSeq Version	NM_213649.2
Organism	Homo sapiens(human)
Definition	Homo sapiens sideroflexin 4 (SFXN4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_213649.2

ORF Insert Sequence:

ATGTCCCTGG AACAGGAGGA GGAAACGCAA CCTGGGCGGC TCCTAGGACG CAGAGACGCC 
GTCCCCGCCT TCATTGAGCC CAACGTGCGC TTCTGGATCA CCGAGCGCCA ATCCTTTATT 
CGACGATTTC TTCAATGGAC AGAATTATTA GATCCTACAA ATGTGTTCAT TTCAGTTGAA 
AGTATAGAAA ACTCGAGGCA ACTATTGTGC ACAAATGAAG ATGTTTCCAG CCCTGCCTCG 
GCGGACCAAA GGATACAAGA AGCTTGGAAG CGGAGTCTTG CAACAGTGCA TCCCGACAGC 
AGCAACCTGA TCCCCAAGCT TTTTCGACCT GCAGCGTTCC TGCCTTTCAT GGCACCCACG 
GTATTTTTGT CAATGACGCC ACTGAAAGGG ATCAAGTCCG TGATTTTACC TCAGGTTTTC 
CTCTGTGCCT ACATGGCAGC GTTCAACAGC ATCAATGGAA ACAGAAGTTA CACTTGTAAG 
CCACTAGAAA GATCATTACT AATGGCGGGA GCCGTTGCTT CTTCAACTTT CTTAGGAGTA 
ATCCCTCAGT TTGTCCAGAT GAAGTATGGC CTGACTGGCC CTTGGATTAA AAGACTCTTA 
CCTGTGATCT TCCTCGTGCA AGCCAGTGGA ATGAATGTCT ACATGTCCCG AAGTCTTGAA 
TCCATTAAGG GGATTGCGGT CATGGACAAG GAAGGCAATG TCCTGGGTCA TTCCAGAATT 
GCTGGGACAA AGGCTGTTAG AGAAACGCTA GCATCCAGAA TAGTGCTGTT TGGGACCTCA 
GCTCTGATTC CTGAAGTCTT CACCTACTTT TTTAAAAGGA CCCAGTATTT CAGGAAAAAC 
CCAGGGTCAT TGTGGATTTT GAAACTGTCT TGTACTGTCC TGGCAATGGG ACTGATGGTG 
CCATTTTCTT TTAGTATATT TCCACAGATT GGACAGATAC AGTACTGTAG TCTTGAAGAG 
AAAATTCAGT CTCCAACAGA AGAAACAGAA ATCTTTTATC ACAGAGGGGT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Macrocytic anemia and mitochondriopathy resulting from a defect in sideroflexin 4.
American journal of human genetics93(5)906-14(2013 Nov)
Hildick-Smith GJ,Cooney JD,Garone C,Kremer LS,Haack TB,Thon JN,Miyata N,Lieber DS,Calvo SE,Akman HO,Yien YY,Huston NC,Branco DS,Shah DI,Freedman ML,Koehler CM,Italiano JE Jr,Merkenschlager A,Beblo S,Strom TM,Meitinger T,Freisinger P,Donati MA,Prokisch H,Mootha VK,DiMauro S,Paw BH

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
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SFXN4 cDNA ORF clone, Homo sapiens(human)

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Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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