Gene Symbol | ZFYVE27 |
Entrez Gene ID | 118813 |
Full Name | zinc finger FYVE-type containing 27 |
Synonyms | PROTRUDIN,SPG33 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear. [provided by RefSeq, Mar 2010]. |
Disorder MIM: | |
Disorder Html: | Spastic paraplegia 33, autosomal dominant, 610244 (3) |