RPL39L cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RPL39L
Entrez Gene ID	116832
Full Name	ribosomal protein L39 like
Synonyms	L39-2,RPL39L1
General protein information	Preferred Names ribosomal protein L39 like Names 60S ribosomal protein L39-like 60S ribosomal protein L39-2 large ribosomal subunit protein eL39-like ribosomal protein L39-like 1 ribosomal protein L39-like protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q27.3
Summary	This gene encodes a protein sharing high sequence similarity with ribosomal protein L39. Although the name of this gene has been referred to as 'ribosomal protein L39' in the public databases, its official name is 'ribosomal protein L39-like'. It is not currently known whether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is independent of the ribosome. [provided by RefSeq, Jul 2008].
Disorder MIM:	607547

mRNA and Protein(s)

mRNA	Protein	Name
NM_052969.2	NP_443201.1	60S ribosomal protein L39-like
NM_052969.1	NP_443201.1	60S ribosomal protein L39-like
NM_052969.3	NP_443201.1	60S ribosomal protein L39-like

Pathways from BioSystems

Homologies

Homo sapiens (human)	RPL39L	NP_443201.1
Pan troglodytes (chimpanzee)	RPL39L	XP_003950300.1

Gene Ontology
Bibliography

Related articles in PubMed

Effects of ribosomal protein l39-L on the drug resistance mechanisms of lung cancer A549 cells.
Liu HS, Tan WB, Yang N, Yang YY, Cheng P, Liu LJ, Wang WJ, Zhu CL
Asian Pacific journal of cancer prevention : APJCP15(7)3093-7(2014)

RPL39L is an example of a recently evolved ribosomal protein paralog that shows highly specific tissue expression patterns and is upregulated in ESCs and HCC tumors.
Wong QW, Li J, Ng SR, Lim SG, Yang H, Vardy LA
RNA biology11(1)33-41(2014)

Influence of ribosomal protein L39-L in the drug resistance mechanisms of lacrimal gland adenoid cystic carcinoma cells.
Ye Q, Ding SF, Wang ZA, Feng J, Tan WB
Asian Pacific journal of cancer prevention : APJCP15(12)4995-5000(2014)

Transcriptome analysis of human gastric cancer.
Oh JH, Yang JO, Hahn Y, Kim MR, Byun SS, Jeon YJ, Kim JM, Song KS, Noh SM, Kim S, Yoo HS, Kim YS, Kim NS
Mammalian genome : official journal of the International Mammalian Genome Society16(12)942-54(2005 Dec)

Functional second genes generated by retrotransposition of the X-linked ribosomal protein genes.
Uechi T, Maeda N, Tanaka T, Kenmochi N
Nucleic acids research30(24)5369-75(2002 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The ribosomal protein L39-L gene may have effects on the drug resistance mechanism of lung cancer A549 cells.
Title: Effects of ribosomal protein l39-L on the drug resistance mechanisms of lung cancer A549 cells.

Results show the RP paralog Rpl39l is highly expressed in Embryonic Stem Cells and its expression strongly correlates with hepatocellular carcinoma tumor (HCC) samples with high tumor grading and alpha-fetoprotein level giving it diagnostic potential.
Title: RPL39L is an example of a recently evolved ribosomal protein paralog that shows highly specific tissue expression patterns and is upregulated in ESCs and HCC tumors.

High RPL39L expression is associated with drug-resistant lacrimal gland adenoid cystic carcinoma.
Title: Influence of ribosomal protein L39-L in the drug resistance mechanisms of lacrimal gland adenoid cystic carcinoma cells.

locus, structure and expression of the gene and its relevance to the biological activities of the ribosome
Title: A human gene encoding a protein homologous to ribosomal protein L39 is normally expressed in the testis and derepressed in multiple cancer cells.

The following RPL39L gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RPL39L cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu05611	NM_052969.3 Latest version!	Homo sapiens ribosomal protein L39 like (RPL39L), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu05611	NM_052969.1	Homo sapiens ribosomal protein L39-like (RPL39L), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu05611	NM_052969.2	Homo sapiens ribosomal protein L39 like (RPL39L), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RPL39L ( NM_052969.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_443201.1 Homo sapiens ribosomal protein L39 like (RPL39L), mRNA.

Price & Availability↑

CloneID	OHu05611
Clone ID Related Accession (Same CDS sequence)	NM_052969.2 , NM_052969.1 , NM_052969.3
Accession Version	NM_052969.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 156bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-03
Organism	Homo sapiens(human)
Product	60S ribosomal protein L39-like
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM769958.1, BC012328.1 and BU674063.1. On Jan 25, 2017 this sequence version replaced NM_052969.1. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.287879.1, SRR1163658.556319.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121

ATGTCTTCTC ACAAGACTTT CACCATTAAG CGATTCCTGG CCAAGAAACA AAAGCAAAAT 
CGTCCCATCC CCCAGTGGAT TCAGATGAAA CCTGGTAGTA AAATCAGGTA CAACTCCAAA 
AGGAGGCATT GGAGAAGAAC CAAGCTGGGT CTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_443201.1
CDS	404..559
Translation	MSSHKTFTIKRFLAKKQKQNRPIPQWIQMKPGSKIRYNSKRRHWRRTKLGL

Target ORF information:

RefSeq Version	NM_052969.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein L39 like (RPL39L), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_052969.2

ORF Insert Sequence:

1
61
121

ATGTCTTCTC ACAAGACTTT CACCATTAAG CGATTCCTGG CCAAGAAACA AAAGCAAAAT 
CGTCCCATCC CCCAGTGGAT TCAGATGAAA CCTGGTAGTA AAATCAGGTA CAACTCCAAA 
AGGAGGCATT GGAGAAGAAC CAAGCTGGGT CTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPL39L ( NM_052969.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_443201.1 Homo sapiens ribosomal protein L39-like (RPL39L), mRNA.

Price & Availability↑

CloneID	OHu05611
Clone ID Related Accession (Same CDS sequence)	NM_052969.2 , NM_052969.1 , NM_052969.3
Accession Version	NM_052969.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 156bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	60S ribosomal protein L39-like
Comment

1
61
121

ATGTCTTCTC ACAAGACTTT CACCATTAAG CGATTCCTGG CCAAGAAACA AAAGCAAAAT 
CGTCCCATCC CCCAGTGGAT TCAGATGAAA CCTGGTAGTA AAATCAGGTA CAACTCCAAA 
AGGAGGCATT GGAGAAGAAC CAAGCTGGGT CTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_443201.1
Translation	MSSHKTFTIKRFLAKKQKQNRPIPQWIQMKPGSKIRYNSKRRHWRRTKLGL

Target ORF information:

RefSeq Version	NM_052969.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens ribosomal protein L39-like (RPL39L), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_052969.1

ORF Insert Sequence:

1
61
121

ATGTCTTCTC ACAAGACTTT CACCATTAAG CGATTCCTGG CCAAGAAACA AAAGCAAAAT 
CGTCCCATCC CCCAGTGGAT TCAGATGAAA CCTGGTAGTA AAATCAGGTA CAACTCCAAA 
AGGAGGCATT GGAGAAGAAC CAAGCTGGGT CTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPL39L ( NM_052969.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_443201.1 Homo sapiens ribosomal protein L39 like (RPL39L), mRNA.

Price & Availability↑

CloneID	OHu05611
Clone ID Related Accession (Same CDS sequence)	NM_052969.2 , NM_052969.1 , NM_052969.3
Accession Version	NM_052969.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 156bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	60S ribosomal protein L39-like
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM769958.1, BC012328.1 and BU674063.1. On Nov 23, 2018 this sequence version replaced NM_052969.2. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.287879.1, SRR5189661.160828.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000296277.9/ ENSP00000296277.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

1
61
121

ATGTCTTCTC ACAAGACTTT CACCATTAAG CGATTCCTGG CCAAGAAACA AAAGCAAAAT 
CGTCCCATCC CCCAGTGGAT TCAGATGAAA CCTGGTAGTA AAATCAGGTA CAACTCCAAA 
AGGAGGCATT GGAGAAGAAC CAAGCTGGGT CTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_443201.1
CDS	377..532
Translation	MSSHKTFTIKRFLAKKQKQNRPIPQWIQMKPGSKIRYNSKRRHWRRTKLGL

Target ORF information:

RefSeq Version	NM_052969.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein L39 like (RPL39L), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_052969.3

ORF Insert Sequence:

1
61
121

ATGTCTTCTC ACAAGACTTT CACCATTAAG CGATTCCTGG CCAAGAAACA AAAGCAAAAT 
CGTCCCATCC CCCAGTGGAT TCAGATGAAA CCTGGTAGTA AAATCAGGTA CAACTCCAAA 
AGGAGGCATT GGAGAAGAAC CAAGCTGGGT CTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Effects of ribosomal protein l39-L on the drug resistance mechanisms of lung cancer A549 cells.
Asian Pacific journal of cancer prevention : APJCP15(7)3093-7(2014)
Liu HS,Tan WB,Yang N,Yang YY,Cheng P,Liu LJ,Wang WJ,Zhu CL

RPL39L is an example of a recently evolved ribosomal protein paralog that shows highly specific tissue expression patterns and is upregulated in ESCs and HCC tumors.
RNA biology11(1)33-41(2014)
Wong QW,Li J,Ng SR,Lim SG,Yang H,Vardy LA

Influence of ribosomal protein L39-L in the drug resistance mechanisms of lacrimal gland adenoid cystic carcinoma cells.
Asian Pacific journal of cancer prevention : APJCP15(12)4995-5000(2014)
Ye Q,Ding SF,Wang ZA,Feng J,Tan WB

Transcriptome analysis of human gastric cancer.
Mammalian genome : official journal of the International Mammalian Genome Society16(12)942-54(2005 Dec)
Oh JH,Yang JO,Hahn Y,Kim MR,Byun SS,Jeon YJ,Kim JM,Song KS,Noh SM,Kim S,Yoo HS,Kim YS,Kim NS

Functional second genes generated by retrotransposition of the X-linked ribosomal protein genes.
Nucleic acids research30(24)5369-75(2002 Dec)
Uechi T,Maeda N,Tanaka T,Kenmochi N

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RPL39L cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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