CKMT2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CKMT2
Entrez Gene ID	1160
Full Name	creatine kinase, mitochondrial 2
Synonyms	SMTCK
General protein information	Preferred Names creatine kinase, mitochondrial 2 Names creatine kinase S-type, mitochondrial S-MtCK basic-type mitochondrial creatine kinase creatine kinase, mitochondrial 2 (sarcomeric) mib-CK sarcomeric mitochondrial creatine kinase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q14.1
Summary	Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	123295

mRNA and Protein(s)

mRNA	Protein	Name
NM_001099735.1	NP_001093205.1	creatine kinase S-type, mitochondrial precursor
NM_001099736.1	NP_001093206.1	creatine kinase S-type, mitochondrial precursor
NM_001825.2	NP_001816.2	creatine kinase S-type, mitochondrial precursor
XM_024454356.1	XP_024310124.1	creatine kinase S-type, mitochondrial isoform X1
NM_001099735.2	NP_001093205.1	creatine kinase S-type, mitochondrial precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	CKMT2	NP_001816.2
Pan troglodytes (chimpanzee)	CKMT2	XP_001149997.1
Mus musculus (house mouse)	Ckmt2	NP_940807.1
	CKMT2	XP_001110817.1
Canis lupus familiaris (dog)	CKMT2	NP_001138686.1
Rattus norvegicus (Norway rat)	Ckmt2	NP_001121124.1
Bos taurus (cattle)	CKMT2	NP_001029828.1
Gallus gallus (chicken)	CKMT2	NP_001161216.1
Danio rerio (zebrafish)	ckmt2b	NP_956991.1

Gene Ontology
Bibliography

Related articles in PubMed

Increasing creatine kinase activity protects against hypoxia / reoxygenation injury but not against anthracycline toxicity in vitro.
Zervou S, Whittington HJ, Ostrowski PJ, Cao F, Tyler J, Lake HA, Neubauer S, Lygate CA
PloS one12(8)e0182994(2017)

Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes.
Zhao X, Le?n IR, Bak S, Mogensen M, Wrzesinski K, H?jlund K, Jensen ON
Molecular & cellular proteomics : MCP10(1)M110.000299(2011 Jan)

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ
PloS one5(9)e12862(2010 Sep)

Protein kinase CK2alpha as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia.
Kim JS, Eom JI, Cheong JW, Choi AJ, Lee JK, Yang WI, Min YH
Clinical cancer research : an official journal of the American Association for Cancer Research13(3)1019-28(2007 Feb)

A human protein-protein interaction network: a resource for annotating the proteome.
Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toks?z E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE
Cell122(6)957-68(2005 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings support increased CK activity as protection against ischaemia-reperfusion injury, in particular, protection via CKMT2 in a cardiac-relevant cell line, which merits further investigation in vivo.
Title: Increasing creatine kinase activity protects against hypoxia / reoxygenation injury but not against anthracycline toxicity in vitro.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

CK2alpha has a role in progression of acute myeloid leukemia
Title: Protein kinase CK2alpha as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia.

After the training period, intracellular energetic units had a higher control of mitochondrial respiration by creatine linked to a more efficient functional coupling adenine nucleotide translocase-mitochondrial creatine kinase.
Title: Functional coupling of adenine nucleotide translocase and mitochondrial creatine kinase is enhanced after exercise training in lung transplant skeletal muscle.

three C-terminal lysines determine high affinity sMtCK/cardiolipin interaction and its effects on MtCK structure, whereas low level binding and some effect on membrane fluidity depend on other structural components
Title: C-terminal lysines determine phospholipid interaction of sarcomeric mitochondrial creatine kinase.

The following CKMT2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CKMT2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu08959	NM_001825.2 Latest version!	Homo sapiens creatine kinase, mitochondrial 2 (CKMT2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu08959	NM_001099735.2 Latest version!	Homo sapiens creatine kinase, mitochondrial 2 (CKMT2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu08959	NM_001099736.1 Latest version!	Homo sapiens creatine kinase, mitochondrial 2 (CKMT2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu105623	XM_024454356.1 Latest version!	Homo sapiens creatine kinase, mitochondrial 2 (CKMT2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu08959	NM_001099735.1	Homo sapiens creatine kinase, mitochondrial 2 (CKMT2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CKMT2 ( NM_001099735.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093205.1 Homo sapiens creatine kinase, mitochondrial 2 (CKMT2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu08959
Clone ID Related Accession (Same CDS sequence)	NM_001099735.1 , NM_001099736.1 , NM_001825.2 , NM_001099735.2
Accession Version	NM_001099735.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-15
Organism	Homo sapiens(human)
Product	creatine kinase S-type, mitochondrial precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB479765.1, BC029140.1 and AW300490.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All three variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279839.9476.1, BC029140.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##

ATGGCCAGTA TCTTTTCTAA GTTGCTAACT GGCCGCAATG CTTCTCTGCT GTTTGCTACC 
ATGGGCACCA GTGTCCTGAC CACCGGGTAC CTGCTGAACC GGCAGAAAGT GTGTGCCGAG 
GTCCGGGAGC AGCCTAGGCT ATTTCCTCCA AGCGCAGACT ACCCAGACCT GCGCAAGCAC 
AACAACTGCA TGGCCGAGTG CCTCACCCCC GCCATTTATG CCAAGCTTCG CAACAAGGTG 
ACACCCAACG GCTACACGCT GGACCAGTGC ATCCAGACTG GAGTGGACAA CCCTGGCCAC 
CCCTTCATAA AGACTGTGGG CATGGTGGCT GGTGACGAGG AGTCCTATGA GGTGTTTGCT 
GACCTTTTTG ACCCCGTCAT CAAACTAAGA CACAACGGCT ATGACCCCAG GGTGATGAAG 
CACACAACGG ATCTGGATGC ATCAAAGATC ACCCAAGGGC AGTTCGACGA GCATTACGTG 
CTGTCTTCTC GGGTGCGCAC TGGCCGCAGC ATCCGTGGGC TGAGCCTGCC TCCAGCCTGC 
ACCCGGGCCG AGCGAAGGGA GGTAGAGAAC GTGGCCATCA CTGCCCTGGA GGGCCTCAAG 
GGGGACCTGG CTGGCCGCTA CTACAAGCTG TCCGAGATGA CGGAGCAGGA CCAGCAGCGG 
CTCATCGATG ACCACTTTCT GTTTGATAAG CCAGTGTCCC CTTTATTAAC ATGTGCTGGG 
ATGGCCCGTG ACTGGCCAGA TGCCAGGGGA ATCTGGCATA ATTATGATAA GACATTTCTC 
ATCTGGATAA ATGAGGAGGA TCACACCAGG GTAATCTCAA TGGAAAAAGG AGGCAATATG 
AAACGAGTAT TTGAGCGATT CTGTCGTGGA CTAAAAGAAG TAGAACGGTT AATCCAAGAA 
CGAGGCTGGG AGTTCATGTG GAATGAGCGC CTAGGATACA TTTTGACCTG TCCTTCGAAC 
CTTGGAACAG GACTACGAGC TGGTGTCCAC GTTAGGATCC CAAAGCTCAG CAAGGACCCA 
CGCTTTTCTA AGATCCTGGA AAACCTAAGA CTCCAGAAGC GTGGCACAGG TGGTGTGGAC 
ACTGCCGCGG TCGCAGATGT GTACGACATT TCCAACATAG ATAGAATTGG TCGATCAGAG 
GTTGAGCTTG TTCAGATAGT CATCGATGGA GTCAATTACC TGGTGGATTG TGAAAAGAAG 
TTGGAGAGAG GCCAAGATAT TAAGGTGCCA CCCCCTCTGC CTCAGTTTGG CAAAAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093205.1
CDS	79..1338
Translation	MASIFSKLLTGRNASLLFATMGTSVLTTGYLLNRQKVCAEVREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQDIKVPPPLPQFGKK

Target ORF information:

RefSeq Version	NM_001099735.1
Organism	Homo sapiens(human)
Definition	Homo sapiens creatine kinase, mitochondrial 2 (CKMT2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001099735.1

ORF Insert Sequence:

ATGGCCAGTA TCTTTTCTAA GTTGCTAACT GGCCGCAATG CTTCTCTGCT GTTTGCTACC 
ATGGGCACCA GTGTCCTGAC CACCGGGTAC CTGCTGAACC GGCAGAAAGT GTGTGCCGAG 
GTCCGGGAGC AGCCTAGGCT ATTTCCTCCA AGCGCAGACT ACCCAGACCT GCGCAAGCAC 
AACAACTGCA TGGCCGAGTG CCTCACCCCC GCCATTTATG CCAAGCTTCG CAACAAGGTG 
ACACCCAACG GCTACACGCT GGACCAGTGC ATCCAGACTG GAGTGGACAA CCCTGGCCAC 
CCCTTCATAA AGACTGTGGG CATGGTGGCT GGTGACGAGG AGTCCTATGA GGTGTTTGCT 
GACCTTTTTG ACCCCGTCAT CAAACTAAGA CACAACGGCT ATGACCCCAG GGTGATGAAG 
CACACAACGG ATCTGGATGC ATCAAAGATC ACCCAAGGGC AGTTCGACGA GCATTACGTG 
CTGTCTTCTC GGGTGCGCAC TGGCCGCAGC ATCCGTGGGC TGAGCCTGCC TCCAGCCTGC 
ACCCGGGCCG AGCGAAGGGA GGTAGAGAAC GTGGCCATCA CTGCCCTGGA GGGCCTCAAG 
GGGGACCTGG CTGGCCGCTA CTACAAGCTG TCCGAGATGA CGGAGCAGGA CCAGCAGCGG 
CTCATCGATG ACCACTTTCT GTTTGATAAG CCAGTGTCCC CTTTATTAAC ATGTGCTGGG 
ATGGCCCGTG ACTGGCCAGA TGCCAGGGGA ATCTGGCATA ATTATGATAA GACATTTCTC 
ATCTGGATAA ATGAGGAGGA TCACACCAGG GTAATCTCAA TGGAAAAAGG AGGCAATATG 
AAACGAGTAT TTGAGCGATT CTGTCGTGGA CTAAAAGAAG TAGAACGGTT AATCCAAGAA 
CGAGGCTGGG AGTTCATGTG GAATGAGCGC CTAGGATACA TTTTGACCTG TCCTTCGAAC 
CTTGGAACAG GACTACGAGC TGGTGTCCAC GTTAGGATCC CAAAGCTCAG CAAGGACCCA 
CGCTTTTCTA AGATCCTGGA AAACCTAAGA CTCCAGAAGC GTGGCACAGG TGGTGTGGAC 
ACTGCCGCGG TCGCAGATGT GTACGACATT TCCAACATAG ATAGAATTGG TCGATCAGAG 
GTTGAGCTTG TTCAGATAGT CATCGATGGA GTCAATTACC TGGTGGATTG TGAAAAGAAG 
TTGGAGAGAG GCCAAGATAT TAAGGTGCCA CCCCCTCTGC CTCAGTTTGG CAAAAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CKMT2 ( NM_001099736.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093206.1 Homo sapiens creatine kinase, mitochondrial 2 (CKMT2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu08959
Clone ID Related Accession (Same CDS sequence)	NM_001099735.1 , NM_001099736.1 , NM_001825.2 , NM_001099735.2
Accession Version	NM_001099736.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	creatine kinase S-type, mitochondrial precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC308656.1, BC029140.1 and AW300490.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All three variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189655.71637.1, SRR5189655.200077.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##

ATGGCCAGTA TCTTTTCTAA GTTGCTAACT GGCCGCAATG CTTCTCTGCT GTTTGCTACC 
ATGGGCACCA GTGTCCTGAC CACCGGGTAC CTGCTGAACC GGCAGAAAGT GTGTGCCGAG 
GTCCGGGAGC AGCCTAGGCT ATTTCCTCCA AGCGCAGACT ACCCAGACCT GCGCAAGCAC 
AACAACTGCA TGGCCGAGTG CCTCACCCCC GCCATTTATG CCAAGCTTCG CAACAAGGTG 
ACACCCAACG GCTACACGCT GGACCAGTGC ATCCAGACTG GAGTGGACAA CCCTGGCCAC 
CCCTTCATAA AGACTGTGGG CATGGTGGCT GGTGACGAGG AGTCCTATGA GGTGTTTGCT 
GACCTTTTTG ACCCCGTCAT CAAACTAAGA CACAACGGCT ATGACCCCAG GGTGATGAAG 
CACACAACGG ATCTGGATGC ATCAAAGATC ACCCAAGGGC AGTTCGACGA GCATTACGTG 
CTGTCTTCTC GGGTGCGCAC TGGCCGCAGC ATCCGTGGGC TGAGCCTGCC TCCAGCCTGC 
ACCCGGGCCG AGCGAAGGGA GGTAGAGAAC GTGGCCATCA CTGCCCTGGA GGGCCTCAAG 
GGGGACCTGG CTGGCCGCTA CTACAAGCTG TCCGAGATGA CGGAGCAGGA CCAGCAGCGG 
CTCATCGATG ACCACTTTCT GTTTGATAAG CCAGTGTCCC CTTTATTAAC ATGTGCTGGG 
ATGGCCCGTG ACTGGCCAGA TGCCAGGGGA ATCTGGCATA ATTATGATAA GACATTTCTC 
ATCTGGATAA ATGAGGAGGA TCACACCAGG GTAATCTCAA TGGAAAAAGG AGGCAATATG 
AAACGAGTAT TTGAGCGATT CTGTCGTGGA CTAAAAGAAG TAGAACGGTT AATCCAAGAA 
CGAGGCTGGG AGTTCATGTG GAATGAGCGC CTAGGATACA TTTTGACCTG TCCTTCGAAC 
CTTGGAACAG GACTACGAGC TGGTGTCCAC GTTAGGATCC CAAAGCTCAG CAAGGACCCA 
CGCTTTTCTA AGATCCTGGA AAACCTAAGA CTCCAGAAGC GTGGCACAGG TGGTGTGGAC 
ACTGCCGCGG TCGCAGATGT GTACGACATT TCCAACATAG ATAGAATTGG TCGATCAGAG 
GTTGAGCTTG TTCAGATAGT CATCGATGGA GTCAATTACC TGGTGGATTG TGAAAAGAAG 
TTGGAGAGAG GCCAAGATAT TAAGGTGCCA CCCCCTCTGC CTCAGTTTGG CAAAAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093206.1
CDS	83..1342
Translation	MASIFSKLLTGRNASLLFATMGTSVLTTGYLLNRQKVCAEVREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQDIKVPPPLPQFGKK

Target ORF information:

RefSeq Version	NM_001099736.1
Organism	Homo sapiens(human)
Definition	Homo sapiens creatine kinase, mitochondrial 2 (CKMT2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001099736.1

ORF Insert Sequence:

ATGGCCAGTA TCTTTTCTAA GTTGCTAACT GGCCGCAATG CTTCTCTGCT GTTTGCTACC 
ATGGGCACCA GTGTCCTGAC CACCGGGTAC CTGCTGAACC GGCAGAAAGT GTGTGCCGAG 
GTCCGGGAGC AGCCTAGGCT ATTTCCTCCA AGCGCAGACT ACCCAGACCT GCGCAAGCAC 
AACAACTGCA TGGCCGAGTG CCTCACCCCC GCCATTTATG CCAAGCTTCG CAACAAGGTG 
ACACCCAACG GCTACACGCT GGACCAGTGC ATCCAGACTG GAGTGGACAA CCCTGGCCAC 
CCCTTCATAA AGACTGTGGG CATGGTGGCT GGTGACGAGG AGTCCTATGA GGTGTTTGCT 
GACCTTTTTG ACCCCGTCAT CAAACTAAGA CACAACGGCT ATGACCCCAG GGTGATGAAG 
CACACAACGG ATCTGGATGC ATCAAAGATC ACCCAAGGGC AGTTCGACGA GCATTACGTG 
CTGTCTTCTC GGGTGCGCAC TGGCCGCAGC ATCCGTGGGC TGAGCCTGCC TCCAGCCTGC 
ACCCGGGCCG AGCGAAGGGA GGTAGAGAAC GTGGCCATCA CTGCCCTGGA GGGCCTCAAG 
GGGGACCTGG CTGGCCGCTA CTACAAGCTG TCCGAGATGA CGGAGCAGGA CCAGCAGCGG 
CTCATCGATG ACCACTTTCT GTTTGATAAG CCAGTGTCCC CTTTATTAAC ATGTGCTGGG 
ATGGCCCGTG ACTGGCCAGA TGCCAGGGGA ATCTGGCATA ATTATGATAA GACATTTCTC 
ATCTGGATAA ATGAGGAGGA TCACACCAGG GTAATCTCAA TGGAAAAAGG AGGCAATATG 
AAACGAGTAT TTGAGCGATT CTGTCGTGGA CTAAAAGAAG TAGAACGGTT AATCCAAGAA 
CGAGGCTGGG AGTTCATGTG GAATGAGCGC CTAGGATACA TTTTGACCTG TCCTTCGAAC 
CTTGGAACAG GACTACGAGC TGGTGTCCAC GTTAGGATCC CAAAGCTCAG CAAGGACCCA 
CGCTTTTCTA AGATCCTGGA AAACCTAAGA CTCCAGAAGC GTGGCACAGG TGGTGTGGAC 
ACTGCCGCGG TCGCAGATGT GTACGACATT TCCAACATAG ATAGAATTGG TCGATCAGAG 
GTTGAGCTTG TTCAGATAGT CATCGATGGA GTCAATTACC TGGTGGATTG TGAAAAGAAG 
TTGGAGAGAG GCCAAGATAT TAAGGTGCCA CCCCCTCTGC CTCAGTTTGG CAAAAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CKMT2 ( NM_001825.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001816.2 Homo sapiens creatine kinase, mitochondrial 2 (CKMT2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu08959
Clone ID Related Accession (Same CDS sequence)	NM_001099735.1 , NM_001099736.1 , NM_001825.2 , NM_001099735.2
Accession Version	NM_001825.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	creatine kinase S-type, mitochondrial precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB479765.1, DA826840.1, BC029140.1 and AW300490.1. On Jul 24, 2007 this sequence version replaced NM_001825.1. Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: J05401.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145240, SAMEA2150585 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCAGTA TCTTTTCTAA GTTGCTAACT GGCCGCAATG CTTCTCTGCT GTTTGCTACC 
ATGGGCACCA GTGTCCTGAC CACCGGGTAC CTGCTGAACC GGCAGAAAGT GTGTGCCGAG 
GTCCGGGAGC AGCCTAGGCT ATTTCCTCCA AGCGCAGACT ACCCAGACCT GCGCAAGCAC 
AACAACTGCA TGGCCGAGTG CCTCACCCCC GCCATTTATG CCAAGCTTCG CAACAAGGTG 
ACACCCAACG GCTACACGCT GGACCAGTGC ATCCAGACTG GAGTGGACAA CCCTGGCCAC 
CCCTTCATAA AGACTGTGGG CATGGTGGCT GGTGACGAGG AGTCCTATGA GGTGTTTGCT 
GACCTTTTTG ACCCCGTCAT CAAACTAAGA CACAACGGCT ATGACCCCAG GGTGATGAAG 
CACACAACGG ATCTGGATGC ATCAAAGATC ACCCAAGGGC AGTTCGACGA GCATTACGTG 
CTGTCTTCTC GGGTGCGCAC TGGCCGCAGC ATCCGTGGGC TGAGCCTGCC TCCAGCCTGC 
ACCCGGGCCG AGCGAAGGGA GGTAGAGAAC GTGGCCATCA CTGCCCTGGA GGGCCTCAAG 
GGGGACCTGG CTGGCCGCTA CTACAAGCTG TCCGAGATGA CGGAGCAGGA CCAGCAGCGG 
CTCATCGATG ACCACTTTCT GTTTGATAAG CCAGTGTCCC CTTTATTAAC ATGTGCTGGG 
ATGGCCCGTG ACTGGCCAGA TGCCAGGGGA ATCTGGCATA ATTATGATAA GACATTTCTC 
ATCTGGATAA ATGAGGAGGA TCACACCAGG GTAATCTCAA TGGAAAAAGG AGGCAATATG 
AAACGAGTAT TTGAGCGATT CTGTCGTGGA CTAAAAGAAG TAGAACGGTT AATCCAAGAA 
CGAGGCTGGG AGTTCATGTG GAATGAGCGC CTAGGATACA TTTTGACCTG TCCTTCGAAC 
CTTGGAACAG GACTACGAGC TGGTGTCCAC GTTAGGATCC CAAAGCTCAG CAAGGACCCA 
CGCTTTTCTA AGATCCTGGA AAACCTAAGA CTCCAGAAGC GTGGCACAGG TGGTGTGGAC 
ACTGCCGCGG TCGCAGATGT GTACGACATT TCCAACATAG ATAGAATTGG TCGATCAGAG 
GTTGAGCTTG TTCAGATAGT CATCGATGGA GTCAATTACC TGGTGGATTG TGAAAAGAAG 
TTGGAGAGAG GCCAAGATAT TAAGGTGCCA CCCCCTCTGC CTCAGTTTGG CAAAAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001816.2
CDS	243..1502
Translation	MASIFSKLLTGRNASLLFATMGTSVLTTGYLLNRQKVCAEVREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQDIKVPPPLPQFGKK

Target ORF information:

RefSeq Version	NM_001825.2
Organism	Homo sapiens(human)
Definition	Homo sapiens creatine kinase, mitochondrial 2 (CKMT2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001825.2

ORF Insert Sequence:

ATGGCCAGTA TCTTTTCTAA GTTGCTAACT GGCCGCAATG CTTCTCTGCT GTTTGCTACC 
ATGGGCACCA GTGTCCTGAC CACCGGGTAC CTGCTGAACC GGCAGAAAGT GTGTGCCGAG 
GTCCGGGAGC AGCCTAGGCT ATTTCCTCCA AGCGCAGACT ACCCAGACCT GCGCAAGCAC 
AACAACTGCA TGGCCGAGTG CCTCACCCCC GCCATTTATG CCAAGCTTCG CAACAAGGTG 
ACACCCAACG GCTACACGCT GGACCAGTGC ATCCAGACTG GAGTGGACAA CCCTGGCCAC 
CCCTTCATAA AGACTGTGGG CATGGTGGCT GGTGACGAGG AGTCCTATGA GGTGTTTGCT 
GACCTTTTTG ACCCCGTCAT CAAACTAAGA CACAACGGCT ATGACCCCAG GGTGATGAAG 
CACACAACGG ATCTGGATGC ATCAAAGATC ACCCAAGGGC AGTTCGACGA GCATTACGTG 
CTGTCTTCTC GGGTGCGCAC TGGCCGCAGC ATCCGTGGGC TGAGCCTGCC TCCAGCCTGC 
ACCCGGGCCG AGCGAAGGGA GGTAGAGAAC GTGGCCATCA CTGCCCTGGA GGGCCTCAAG 
GGGGACCTGG CTGGCCGCTA CTACAAGCTG TCCGAGATGA CGGAGCAGGA CCAGCAGCGG 
CTCATCGATG ACCACTTTCT GTTTGATAAG CCAGTGTCCC CTTTATTAAC ATGTGCTGGG 
ATGGCCCGTG ACTGGCCAGA TGCCAGGGGA ATCTGGCATA ATTATGATAA GACATTTCTC 
ATCTGGATAA ATGAGGAGGA TCACACCAGG GTAATCTCAA TGGAAAAAGG AGGCAATATG 
AAACGAGTAT TTGAGCGATT CTGTCGTGGA CTAAAAGAAG TAGAACGGTT AATCCAAGAA 
CGAGGCTGGG AGTTCATGTG GAATGAGCGC CTAGGATACA TTTTGACCTG TCCTTCGAAC 
CTTGGAACAG GACTACGAGC TGGTGTCCAC GTTAGGATCC CAAAGCTCAG CAAGGACCCA 
CGCTTTTCTA AGATCCTGGA AAACCTAAGA CTCCAGAAGC GTGGCACAGG TGGTGTGGAC 
ACTGCCGCGG TCGCAGATGT GTACGACATT TCCAACATAG ATAGAATTGG TCGATCAGAG 
GTTGAGCTTG TTCAGATAGT CATCGATGGA GTCAATTACC TGGTGGATTG TGAAAAGAAG 
TTGGAGAGAG GCCAAGATAT TAAGGTGCCA CCCCCTCTGC CTCAGTTTGG CAAAAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CKMT2 ( NM_001099735.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093205.1 Homo sapiens creatine kinase, mitochondrial 2 (CKMT2), transcript variant 2, mRNA.

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CloneID	OHu08959
Clone ID Related Accession (Same CDS sequence)	NM_001099735.1 , NM_001099736.1 , NM_001825.2 , NM_001099735.2
Accession Version	NM_001099735.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	creatine kinase S-type, mitochondrial precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB479765.1, BC029140.1 and AW300490.1. On Nov 23, 2018 this sequence version replaced NM_001099735.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All three variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189655.63632.1, SRR5189655.117948.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta MANE Ensembl match :: ENST00000254035.9/ ENSP00000254035.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCAGTA TCTTTTCTAA GTTGCTAACT GGCCGCAATG CTTCTCTGCT GTTTGCTACC 
ATGGGCACCA GTGTCCTGAC CACCGGGTAC CTGCTGAACC GGCAGAAAGT GTGTGCCGAG 
GTCCGGGAGC AGCCTAGGCT ATTTCCTCCA AGCGCAGACT ACCCAGACCT GCGCAAGCAC 
AACAACTGCA TGGCCGAGTG CCTCACCCCC GCCATTTATG CCAAGCTTCG CAACAAGGTG 
ACACCCAACG GCTACACGCT GGACCAGTGC ATCCAGACTG GAGTGGACAA CCCTGGCCAC 
CCCTTCATAA AGACTGTGGG CATGGTGGCT GGTGACGAGG AGTCCTATGA GGTGTTTGCT 
GACCTTTTTG ACCCCGTCAT CAAACTAAGA CACAACGGCT ATGACCCCAG GGTGATGAAG 
CACACAACGG ATCTGGATGC ATCAAAGATC ACCCAAGGGC AGTTCGACGA GCATTACGTG 
CTGTCTTCTC GGGTGCGCAC TGGCCGCAGC ATCCGTGGGC TGAGCCTGCC TCCAGCCTGC 
ACCCGGGCCG AGCGAAGGGA GGTAGAGAAC GTGGCCATCA CTGCCCTGGA GGGCCTCAAG 
GGGGACCTGG CTGGCCGCTA CTACAAGCTG TCCGAGATGA CGGAGCAGGA CCAGCAGCGG 
CTCATCGATG ACCACTTTCT GTTTGATAAG CCAGTGTCCC CTTTATTAAC ATGTGCTGGG 
ATGGCCCGTG ACTGGCCAGA TGCCAGGGGA ATCTGGCATA ATTATGATAA GACATTTCTC 
ATCTGGATAA ATGAGGAGGA TCACACCAGG GTAATCTCAA TGGAAAAAGG AGGCAATATG 
AAACGAGTAT TTGAGCGATT CTGTCGTGGA CTAAAAGAAG TAGAACGGTT AATCCAAGAA 
CGAGGCTGGG AGTTCATGTG GAATGAGCGC CTAGGATACA TTTTGACCTG TCCTTCGAAC 
CTTGGAACAG GACTACGAGC TGGTGTCCAC GTTAGGATCC CAAAGCTCAG CAAGGACCCA 
CGCTTTTCTA AGATCCTGGA AAACCTAAGA CTCCAGAAGC GTGGCACAGG TGGTGTGGAC 
ACTGCCGCGG TCGCAGATGT GTACGACATT TCCAACATAG ATAGAATTGG TCGATCAGAG 
GTTGAGCTTG TTCAGATAGT CATCGATGGA GTCAATTACC TGGTGGATTG TGAAAAGAAG 
TTGGAGAGAG GCCAAGATAT TAAGGTGCCA CCCCCTCTGC CTCAGTTTGG CAAAAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093205.1
CDS	77..1336
Translation	MASIFSKLLTGRNASLLFATMGTSVLTTGYLLNRQKVCAEVREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQDIKVPPPLPQFGKK

Target ORF information:

RefSeq Version	NM_001099735.2
Organism	Homo sapiens(human)
Definition	Homo sapiens creatine kinase, mitochondrial 2 (CKMT2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001099735.2

ORF Insert Sequence:

ATGGCCAGTA TCTTTTCTAA GTTGCTAACT GGCCGCAATG CTTCTCTGCT GTTTGCTACC 
ATGGGCACCA GTGTCCTGAC CACCGGGTAC CTGCTGAACC GGCAGAAAGT GTGTGCCGAG 
GTCCGGGAGC AGCCTAGGCT ATTTCCTCCA AGCGCAGACT ACCCAGACCT GCGCAAGCAC 
AACAACTGCA TGGCCGAGTG CCTCACCCCC GCCATTTATG CCAAGCTTCG CAACAAGGTG 
ACACCCAACG GCTACACGCT GGACCAGTGC ATCCAGACTG GAGTGGACAA CCCTGGCCAC 
CCCTTCATAA AGACTGTGGG CATGGTGGCT GGTGACGAGG AGTCCTATGA GGTGTTTGCT 
GACCTTTTTG ACCCCGTCAT CAAACTAAGA CACAACGGCT ATGACCCCAG GGTGATGAAG 
CACACAACGG ATCTGGATGC ATCAAAGATC ACCCAAGGGC AGTTCGACGA GCATTACGTG 
CTGTCTTCTC GGGTGCGCAC TGGCCGCAGC ATCCGTGGGC TGAGCCTGCC TCCAGCCTGC 
ACCCGGGCCG AGCGAAGGGA GGTAGAGAAC GTGGCCATCA CTGCCCTGGA GGGCCTCAAG 
GGGGACCTGG CTGGCCGCTA CTACAAGCTG TCCGAGATGA CGGAGCAGGA CCAGCAGCGG 
CTCATCGATG ACCACTTTCT GTTTGATAAG CCAGTGTCCC CTTTATTAAC ATGTGCTGGG 
ATGGCCCGTG ACTGGCCAGA TGCCAGGGGA ATCTGGCATA ATTATGATAA GACATTTCTC 
ATCTGGATAA ATGAGGAGGA TCACACCAGG GTAATCTCAA TGGAAAAAGG AGGCAATATG 
AAACGAGTAT TTGAGCGATT CTGTCGTGGA CTAAAAGAAG TAGAACGGTT AATCCAAGAA 
CGAGGCTGGG AGTTCATGTG GAATGAGCGC CTAGGATACA TTTTGACCTG TCCTTCGAAC 
CTTGGAACAG GACTACGAGC TGGTGTCCAC GTTAGGATCC CAAAGCTCAG CAAGGACCCA 
CGCTTTTCTA AGATCCTGGA AAACCTAAGA CTCCAGAAGC GTGGCACAGG TGGTGTGGAC 
ACTGCCGCGG TCGCAGATGT GTACGACATT TCCAACATAG ATAGAATTGG TCGATCAGAG 
GTTGAGCTTG TTCAGATAGT CATCGATGGA GTCAATTACC TGGTGGATTG TGAAAAGAAG 
TTGGAGAGAG GCCAAGATAT TAAGGTGCCA CCCCCTCTGC CTCAGTTTGG CAAAAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CKMT2 ( XM_024454356.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024310124.1 Homo sapiens creatine kinase, mitochondrial 2 (CKMT2), transcript variant X1, mRNA.

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CloneID	OHu105623
Clone ID Related Accession (Same CDS sequence)	XM_024454356.1
Accession Version	XM_024454356.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1611bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	creatine kinase S-type, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCAATT TCACCTGCTG GCCCTTCCAT TCTGAGATCC AGAGCCCTGG CAAAGGAGCC 
TCCAGGACCA GGCCTGGGAA GCAAGACTGG CTCCGCCTTT TACGTTTCAG AGAAAGGGCA 
GGTGCTATAA AGGGCCCAGC GCCCACGGGC CTGCCTTCAA GGGTACAGCT GTGGGGGCCG 
GTGCGCCCGG AGGTCTACGC TGGGATTGGT GAGGTCCTCT GGCCCCGCCC CGCCAGGGAG 
GATTTCCAGG CCGGCCCGAC CAGCTCGCCC TGCATACACT TCTTGGCTGT GTGCGCTCAG 
CAGGACGTGG GAGGCTCCGG CTTCAAGGTC GACACTCATC CAAGAGGAAG GATGGCCAGT 
ATCTTTTCTA AGTTGCTAAC TGGCCGCAAT GCTTCTCTGC TGTTTGCTAC CATGGGCACC 
AGTGTCCTGA CCACCGGGTA CCTGCTGAAC CGGCAGAAAG TGTGTGCCGA GGTCCGGGAG 
CAGCCTAGGC TATTTCCTCC AAGCGCAGAC TACCCAGACC TGCGCAAGCA CAACAACTGC 
ATGGCCGAGT GCCTCACCCC CGCCATTTAT GCCAAGCTTC GCAACAAGGT GACACCCAAC 
GGCTACACGC TGGACCAGTG CATCCAGACT GGAGTGGACA ACCCTGGCCA CCCCTTCATA 
AAGACTGTGG GCATGGTGGC TGGTGACGAG GAGTCCTATG AGGTGTTTGC TGACCTTTTT 
GACCCCGTCA TCAAACTAAG ACACAACGGC TATGACCCCA GGGTGATGAA GCACACAACG 
GATCTGGATG CATCAAAGAT CACCCAAGGG CAGTTCGACG AGCATTACGT GCTGTCTTCT 
CGGGTGCGCA CTGGCCGCAG CATCCGTGGG CTGAGCCTGC CTCCAGCCTG CACCCGGGCC 
GAGCGAAGGG AGGTAGAGAA CGTGGCCATC ACTGCCCTGG AGGGCCTCAA GGGGGACCTG 
GCTGGCCGCT ACTACAAGCT GTCCGAGATG ACGGAGCAGG ACCAGCAGCG GCTCATCGAT 
GACCACTTTC TGTTTGATAA GCCAGTGTCC CCTTTATTAA CATGTGCTGG GATGGCCCGT 
GACTGGCCAG ATGCCAGGGG AATCTGGCAT AATTATGATA AGACATTTCT CATCTGGATA 
AATGAGGAGG ATCACACCAG GGTAATCTCA ATGGAAAAAG GAGGCAATAT GAAACGAGTA 
TTTGAGCGAT TCTGTCGTGG ACTAAAAGAA GTAGAACGGT TAATCCAAGA ACGAGGCTGG 
GAGTTCATGT GGAATGAGCG CCTAGGATAC ATTTTGACCT GTCCTTCGAA CCTTGGAACA 
GGACTACGAG CTGGTGTCCA CGTTAGGATC CCAAAGCTCA GCAAGGACCC ACGCTTTTCT 
AAGATCCTGG AAAACCTAAG ACTCCAGAAG CGTGGCACAG GTGGTGTGGA CACTGCCGCG 
GTCGCAGATG TGTACGACAT TTCCAACATA GATAGAATTG GTCGATCAGA GGTTGAGCTT 
GTTCAGATAG TCATCGATGG AGTCAATTAC CTGGTGGATT GTGAAAAGAA GTTGGAGAGA 
GGCCAAGATA TTAAGGTGCC ACCCCCTCTG CCTCAGTTTG GCAAAAAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024310124.1
CDS	5457..7067
Translation	MCNFTCWPFHSEIQSPGKGASRTRPGKQDWLRLLRFRERAGAIKGPAPTGLPSRVQLWGPVRPEVYAGIGEVLWPRPAREDFQAGPTSSPCIHFLAVCAQQDVGGSGFKVDTHPRGRMASIFSKLLTGRNASLLFATMGTSVLTTGYLLNRQKVCAEVREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQDIKVPPPLPQFGKK

Target ORF information:

RefSeq Version	XM_024454356.1
Organism	Homo sapiens(human)
Definition	Homo sapiens creatine kinase, mitochondrial 2 (CKMT2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024454356.1

ORF Insert Sequence:

ATGTGCAATT TCACCTGCTG GCCCTTCCAT TCTGAGATCC AGAGCCCTGG CAAAGGAGCC 
TCCAGGACCA GGCCTGGGAA GCAAGACTGG CTCCGCCTTT TACGTTTCAG AGAAAGGGCA 
GGTGCTATAA AGGGCCCAGC GCCCACGGGC CTGCCTTCAA GGGTACAGCT GTGGGGGCCG 
GTGCGCCCGG AGGTCTACGC TGGGATTGGT GAGGTCCTCT GGCCCCGCCC CGCCAGGGAG 
GATTTCCAGG CCGGCCCGAC CAGCTCGCCC TGCATACACT TCTTGGCTGT GTGCGCTCAG 
CAGGACGTGG GAGGCTCCGG CTTCAAGGTC GACACTCATC CAAGAGGAAG GATGGCCAGT 
ATCTTTTCTA AGTTGCTAAC TGGCCGCAAT GCTTCTCTGC TGTTTGCTAC CATGGGCACC 
AGTGTCCTGA CCACCGGGTA CCTGCTGAAC CGGCAGAAAG TGTGTGCCGA GGTCCGGGAG 
CAGCCTAGGC TATTTCCTCC AAGCGCAGAC TACCCAGACC TGCGCAAGCA CAACAACTGC 
ATGGCCGAGT GCCTCACCCC CGCCATTTAT GCCAAGCTTC GCAACAAGGT GACACCCAAC 
GGCTACACGC TGGACCAGTG CATCCAGACT GGAGTGGACA ACCCTGGCCA CCCCTTCATA 
AAGACTGTGG GCATGGTGGC TGGTGACGAG GAGTCCTATG AGGTGTTTGC TGACCTTTTT 
GACCCCGTCA TCAAACTAAG ACACAACGGC TATGACCCCA GGGTGATGAA GCACACAACG 
GATCTGGATG CATCAAAGAT CACCCAAGGG CAGTTCGACG AGCATTACGT GCTGTCTTCT 
CGGGTGCGCA CTGGCCGCAG CATCCGTGGG CTGAGCCTGC CTCCAGCCTG CACCCGGGCC 
GAGCGAAGGG AGGTAGAGAA CGTGGCCATC ACTGCCCTGG AGGGCCTCAA GGGGGACCTG 
GCTGGCCGCT ACTACAAGCT GTCCGAGATG ACGGAGCAGG ACCAGCAGCG GCTCATCGAT 
GACCACTTTC TGTTTGATAA GCCAGTGTCC CCTTTATTAA CATGTGCTGG GATGGCCCGT 
GACTGGCCAG ATGCCAGGGG AATCTGGCAT AATTATGATA AGACATTTCT CATCTGGATA 
AATGAGGAGG ATCACACCAG GGTAATCTCA ATGGAAAAAG GAGGCAATAT GAAACGAGTA 
TTTGAGCGAT TCTGTCGTGG ACTAAAAGAA GTAGAACGGT TAATCCAAGA ACGAGGCTGG 
GAGTTCATGT GGAATGAGCG CCTAGGATAC ATTTTGACCT GTCCTTCGAA CCTTGGAACA 
GGACTACGAG CTGGTGTCCA CGTTAGGATC CCAAAGCTCA GCAAGGACCC ACGCTTTTCT 
AAGATCCTGG AAAACCTAAG ACTCCAGAAG CGTGGCACAG GTGGTGTGGA CACTGCCGCG 
GTCGCAGATG TGTACGACAT TTCCAACATA GATAGAATTG GTCGATCAGA GGTTGAGCTT 
GTTCAGATAG TCATCGATGG AGTCAATTAC CTGGTGGATT GTGAAAAGAA GTTGGAGAGA 
GGCCAAGATA TTAAGGTGCC ACCCCCTCTG CCTCAGTTTG GCAAAAAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Increasing creatine kinase activity protects against hypoxia / reoxygenation injury but not against anthracycline toxicity in vitro.
PloS one12(8)e0182994(2017)
Zervou S,Whittington HJ,Ostrowski PJ,Cao F,Tyler J,Lake HA,Neubauer S,Lygate CA

Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes.
Molecular & cellular proteomics : MCP10(1)M110.000299(2011 Jan)
Zhao X,Le?n IR,Bak S,Mogensen M,Wrzesinski K,H?jlund K,Jensen ON

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
PloS one5(9)e12862(2010 Sep)
Hendrickson SL,Lautenberger JA,Chinn LW,Malasky M,Sezgin E,Kingsley LA,Goedert JJ,Kirk GD,Gomperts ED,Buchbinder SP,Troyer JL,O'Brien SJ

Protein kinase CK2alpha as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research13(3)1019-28(2007 Feb)
Kim JS,Eom JI,Cheong JW,Choi AJ,Lee JK,Yang WI,Min YH

A human protein-protein interaction network: a resource for annotating the proteome.
Cell122(6)957-68(2005 Sep)
Stelzl U,Worm U,Lalowski M,Haenig C,Brembeck FH,Goehler H,Stroedicke M,Zenkner M,Schoenherr A,Koeppen S,Timm J,Mintzlaff S,Abraham C,Bock N,Kietzmann S,Goedde A,Toks?z E,Droege A,Krobitsch S,Korn B,Birchmeier W,Lehrach H,Wanker EE

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CKMT2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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