OSBPL11 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	OSBPL11
Entrez Gene ID	114885
Full Name	oxysterol binding protein like 11
Synonyms	ORP-11,ORP11,OSBP12,TCCCIA00292
General protein information	Preferred Names oxysterol binding protein like 11 Names oxysterol-binding protein-related protein 11 OSBP-related protein 11 testicular tissue protein Li 132
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q21.2
Summary	This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. [provided by RefSeq, Jul 2008].
Disorder MIM:	606739

mRNA and Protein(s)

mRNA	Protein	Name
NM_022776.4	NP_073613.2	oxysterol-binding protein-related protein 11
NM_022776.5	NP_073613.2	oxysterol-binding protein-related protein 11

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	OSBPL11	XP_003640171.1
Homo sapiens (human)	OSBPL11	NP_073613.2
	OSBPL11	XP_001114179.1
Bos taurus (cattle)	OSBPL11	NP_001179937.1
Mus musculus (house mouse)	Osbpl11	NP_789810.2
Danio rerio (zebrafish)	osbpl11	XP_689013.3
Rattus norvegicus (Norway rat)	Osbpl11	NP_001100560.1
Xenopus tropicalis (tropical clawed frog)	osbpl11	NP_001025662.1
Pan troglodytes (chimpanzee)	OSBPL11	XP_001169528.1
Gallus gallus (chicken)	OSBPL11	XP_004943013.1

Gene Ontology
Bibliography

Related articles in PubMed

OSBP-related proteins (ORPs) in human adipose depots and cultured adipocytes: evidence for impacts on the adipocyte phenotype.
Zhou Y, Robciuc MR, Wabitsch M, Juuti A, Leivonen M, Ehnholm C, Yki-J?rvinen H, Olkkonen VM
PloS one7(9)e45352(2012)

OSBP-related protein 11 (ORP11) dimerizes with ORP9 and localizes at the Golgi-late endosome interface.
Zhou Y, Li S, M?yr?np?? MI, Zhong W, B?ck N, Yan D, Olkkonen VM
Experimental cell research316(19)3304-16(2010 Nov)

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S,
Diabetes care33(10)2250-3(2010 Oct)

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, , ,
American journal of human genetics85(5)628-42(2009 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ORP8 overexpression resulted in reduced expression of the aP2 mRNA, while down-regulation of adiponectin and aP2 was observed in ORP11 silenced cells. ORP8 overexpression or silencing of ORP11 markedly decreased cellular triglyceride storage.
Title: OSBP-related proteins (ORPs) in human adipose depots and cultured adipocytes: evidence for impacts on the adipocyte phenotype.

The results identify ORP11 as an OSBP homologue distributing at the Golgi-LE interface and define the ORP9-ORP11 dimer as a functional unit that may act as an intracellular lipid sensor or transporter.
Title: OSBP-related protein 11 (ORP11) dimerizes with ORP9 and localizes at the Golgi-late endosome interface.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

The OSBPL11 gene is involved in cholesterol and glucose metabolism in obese individuals.
Title: Association of OSBPL11 gene polymorphisms with cardiovascular disease risk factors in obesity.

The following OSBPL11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OSBPL11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu03919	NM_022776.5 Latest version!	Homo sapiens oxysterol binding protein like 11 (OSBPL11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
View Old Accession Versions >>
OHu03919	NM_022776.4	Homo sapiens oxysterol binding protein like 11 (OSBPL11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

OSBPL11 ( NM_022776.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_073613.2 Homo sapiens oxysterol binding protein like 11 (OSBPL11), mRNA.

Price & Availability↑

CloneID	OHu03919
Clone ID Related Accession (Same CDS sequence)	NM_022776.4 , NM_022776.5
Accession Version	NM_022776.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2244bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	oxysterol-binding protein-related protein 11
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA722217.1, DA112146.1, BX506747.1 and BC065213.1. On Nov 23, 2018 this sequence version replaced NM_022776.4. ##Evidence-Data-START## Transcript exon combination :: BC065213.1, SRR1803615.78789.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000296220.6/ ENSP00000296220.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCAGGGGG GTGAACCAGT GTCCACAATG AAAGTCTCGG AGAGCGAAGG AAAGCTGGAG 
GGCCAGGCCA CAGCGGTGAC CCCGAACAAG AACAGCAGCT GTGGAGGTGG AATCAGTAGC 
AGCAGCAGCA GCCGCGGTGG CAGTGCAAAA GGCTGGCAGT ACAGTGATCA CATGGAAAAT 
GTGTATGGCT ATTTAATGAA GTATACCAAC CTTGTCACTG GGTGGCAGTA CAGGTTTTTT 
GTTTTAAACA ATGAAGCTGG GCTGTTGGAG TACTTTGTGA ATGAACAGTC TAGAAATCAG 
AAACCTAGAG GAACTTTGCA GCTTGCAGGA GCTGTAATAT CACCCAGTGA TGAGGATTCT 
CACACCTTCA CTGTAAACGC TGCCAGTGGG GAACAATATA AACTCAGAGC TACAGATGCA 
AAAGAGCGAC AGCACTGGGT TAGCAGACTT CAGATATGTA CACAGCATCA TACTGAAGCT 
ATTGGAAAGA ATAATCCTCC TCTGAAGTCA CGGAGCTTCT CACTTGCATC TAGTAGTAAT 
TCTCCTATAT CGCAGAGGAG ACCAAGTCAA AATGCCATTT CTTTTTTTAA TGTTGGACAT 
TCCAAACTGC AATCACTGAG CAAAAGAACT AATTTACCTC CAGACCATCT TGTGGAAGTC 
AGAGAAATGA TGTCTCATGC TGAAGGACAA CAAAGAGACT TAATTAGACG AATTGAATGC 
CTTCCTACTT CTGGCCATCT TAGTTCCTTG GACCAGGATC TCTTAATGCT CAAAGCTACT 
TCCATGGCAA CTATGAACTG CTTAAATGAC TGCTTTCATA TTCTCCAGTT ACAGCATGCA 
TCACATCAGA AGGGCTCATT GCCTTCAGGA ACGACAATCG AGTGGTTAGA ACCAAAGATA 
TCTTTATCAA ACCACTATAA AAATGGAGCT GACCAGCCCT TTGCAACTGA TCAGAGTAAG 
CCGGTGGCAG TCCCAGAAGA GCAGCCTGTT GCAGAATCTG GACTATTAGC GAGGGAGCCT 
GAAGAAATAA ATGCAGATGA TGAGATAGAG GATACATGTG ACCACAAAGA GGATGACCTG 
GGAGCTGTAG AAGAACAACG TAGTGTCATC CTACATCTCT TGTCACAGCT TAAGCTGGGC 
ATGGATTTAA CAAGAGTGGT GCTTCCTACA TTTATCCTAG AGAAGCGTTC CTTGCTGGAA 
ATGTATGCAG ACTTTATGTC TCATCCAGAC CTATTTATAG CCATCACTAA TGGAGCCACA 
GCTGAGGACA GAATGATTCG CTTTGTTGAG TACTACCTTA CCTCATTTCA TGAAGGCCGT 
AAGGGAGCCA TTGCTAAAAA ACCATACAAT CCTATCATTG GAGAAACATT TCACTGTTCC 
TGGAAGATGC CAAAAAGCGA GGTAGCATCC AGTGTTTTTA GCAGTTCTTC CACCCAGGGA 
GTCACAAATC ATGCTCCTTT ATCGGGGGAG TCTTTGACCC AGGTGGGATC AGACTGTTAC 
ACAGTCAGAT TTGTTGCTGA GCAGGTTTCT CATCATCCTC CAGTCTCAGG ATTTTATGCA 
GAATGTACAG AGAGGAAGAT GTGTGTAAAT GCGCATGTCT GGACTAAGAG CAAGTTCTTA 
GGCATGTCAA TAGGCGTGAC AATGGTTGGA GAAGGTATCC TTAGTCTGTT GGAGCATGGA 
GAAGAGTACA CATTTTCTCT ACCCTGTGCA TATGCTCGGT CAATTTTGAC TGTTCCTTGG 
GTAGAACTGG GTGGCAAAGT CAGTGTCAAC TGTGCAAAAA CTGGATATTC AGCCAGCATC 
ACTTTTCATA CCAAGCCATT TTATGGTGGC AAACTGCATC GGGTTACAGC TGAAGTAAAG 
CACAACATCA CCAACACTGT GGTATGCAGA GTGCAAGGGG AATGGAATAG TGTTCTTGAG 
TTCACATATA GCAATGGAGA GACAAAGTAT GTGGACTTGA CTAAATTGGC AGTGACGAAG 
AAAAGAGTGA GACCTCTGGA GAAGCAGGAT CCATTTGAAT CCAGGCGATT GTGGAAAAAT 
GTGACAGACT CGCTGAGAGA ATCTGAAATT GATAAGGCCA CAGAGCATAA GCATACCCTG 
GAAGAACGTC AGAGGACTGA AGAAAGGCAT CGTACTGAAA CAGGCACACC TTGGAAAACC 
AAATATTTTA TTAAAGAGGG AGATGGCTGG GTTTATCATA AACCACTTTG GAAAATAATT 
CCAACAACAC AACCAGCAGA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_073613.2
CDS	698..2941
Translation	MQGGEPVSTMKVSESEGKLEGQATAVTPNKNSSCGGGISSSSSSRGGSAKGWQYSDHMENVYGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSSNSPISQRRPSQNAISFFNVGHSKLQSLSKRTNLPPDHLVEVREMMSHAEGQQRDLIRRIECLPTSGHLSSLDQDLLMLKATSMATMNCLNDCFHILQLQHASHQKGSLPSGTTIEWLEPKISLSNHYKNGADQPFATDQSKPVAVPEEQPVAESGLLAREPEEINADDEIEDTCDHKEDDLGAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEFTYSNGETKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWKIIPTTQPAE

Target ORF information:

RefSeq Version	NM_022776.5
Organism	Homo sapiens(human)
Definition	Homo sapiens oxysterol binding protein like 11 (OSBPL11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022776.5

ORF Insert Sequence:

ATGCAGGGGG GTGAACCAGT GTCCACAATG AAAGTCTCGG AGAGCGAAGG AAAGCTGGAG 
GGCCAGGCCA CAGCGGTGAC CCCGAACAAG AACAGCAGCT GTGGAGGTGG AATCAGTAGC 
AGCAGCAGCA GCCGCGGTGG CAGTGCAAAA GGCTGGCAGT ACAGTGATCA CATGGAAAAT 
GTGTATGGCT ATTTAATGAA GTATACCAAC CTTGTCACTG GGTGGCAGTA CAGGTTTTTT 
GTTTTAAACA ATGAAGCTGG GCTGTTGGAG TACTTTGTGA ATGAACAGTC TAGAAATCAG 
AAACCTAGAG GAACTTTGCA GCTTGCAGGA GCTGTAATAT CACCCAGTGA TGAGGATTCT 
CACACCTTCA CTGTAAACGC TGCCAGTGGG GAACAATATA AACTCAGAGC TACAGATGCA 
AAAGAGCGAC AGCACTGGGT TAGCAGACTT CAGATATGTA CACAGCATCA TACTGAAGCT 
ATTGGAAAGA ATAATCCTCC TCTGAAGTCA CGGAGCTTCT CACTTGCATC TAGTAGTAAT 
TCTCCTATAT CGCAGAGGAG ACCAAGTCAA AATGCCATTT CTTTTTTTAA TGTTGGACAT 
TCCAAACTGC AATCACTGAG CAAAAGAACT AATTTACCTC CAGACCATCT TGTGGAAGTC 
AGAGAAATGA TGTCTCATGC TGAAGGACAA CAAAGAGACT TAATTAGACG AATTGAATGC 
CTTCCTACTT CTGGCCATCT TAGTTCCTTG GACCAGGATC TCTTAATGCT CAAAGCTACT 
TCCATGGCAA CTATGAACTG CTTAAATGAC TGCTTTCATA TTCTCCAGTT ACAGCATGCA 
TCACATCAGA AGGGCTCATT GCCTTCAGGA ACGACAATCG AGTGGTTAGA ACCAAAGATA 
TCTTTATCAA ACCACTATAA AAATGGAGCT GACCAGCCCT TTGCAACTGA TCAGAGTAAG 
CCGGTGGCAG TCCCAGAAGA GCAGCCTGTT GCAGAATCTG GACTATTAGC GAGGGAGCCT 
GAAGAAATAA ATGCAGATGA TGAGATAGAG GATACATGTG ACCACAAAGA GGATGACCTG 
GGAGCTGTAG AAGAACAACG TAGTGTCATC CTACATCTCT TGTCACAGCT TAAGCTGGGC 
ATGGATTTAA CAAGAGTGGT GCTTCCTACA TTTATCCTAG AGAAGCGTTC CTTGCTGGAA 
ATGTATGCAG ACTTTATGTC TCATCCAGAC CTATTTATAG CCATCACTAA TGGAGCCACA 
GCTGAGGACA GAATGATTCG CTTTGTTGAG TACTACCTTA CCTCATTTCA TGAAGGCCGT 
AAGGGAGCCA TTGCTAAAAA ACCATACAAT CCTATCATTG GAGAAACATT TCACTGTTCC 
TGGAAGATGC CAAAAAGCGA GGTAGCATCC AGTGTTTTTA GCAGTTCTTC CACCCAGGGA 
GTCACAAATC ATGCTCCTTT ATCGGGGGAG TCTTTGACCC AGGTGGGATC AGACTGTTAC 
ACAGTCAGAT TTGTTGCTGA GCAGGTTTCT CATCATCCTC CAGTCTCAGG ATTTTATGCA 
GAATGTACAG AGAGGAAGAT GTGTGTAAAT GCGCATGTCT GGACTAAGAG CAAGTTCTTA 
GGCATGTCAA TAGGCGTGAC AATGGTTGGA GAAGGTATCC TTAGTCTGTT GGAGCATGGA 
GAAGAGTACA CATTTTCTCT ACCCTGTGCA TATGCTCGGT CAATTTTGAC TGTTCCTTGG 
GTAGAACTGG GTGGCAAAGT CAGTGTCAAC TGTGCAAAAA CTGGATATTC AGCCAGCATC 
ACTTTTCATA CCAAGCCATT TTATGGTGGC AAACTGCATC GGGTTACAGC TGAAGTAAAG 
CACAACATCA CCAACACTGT GGTATGCAGA GTGCAAGGGG AATGGAATAG TGTTCTTGAG 
TTCACATATA GCAATGGAGA GACAAAGTAT GTGGACTTGA CTAAATTGGC AGTGACGAAG 
AAAAGAGTGA GACCTCTGGA GAAGCAGGAT CCATTTGAAT CCAGGCGATT GTGGAAAAAT 
GTGACAGACT CGCTGAGAGA ATCTGAAATT GATAAGGCCA CAGAGCATAA GCATACCCTG 
GAAGAACGTC AGAGGACTGA AGAAAGGCAT CGTACTGAAA CAGGCACACC TTGGAAAACC 
AAATATTTTA TTAAAGAGGG AGATGGCTGG GTTTATCATA AACCACTTTG GAAAATAATT 
CCAACAACAC AACCAGCAGA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OSBPL11 ( NM_022776.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_073613.2 Homo sapiens oxysterol binding protein like 11 (OSBPL11), mRNA.

Price & Availability↑

CloneID	OHu03919
Clone ID Related Accession (Same CDS sequence)	NM_022776.4 , NM_022776.5
Accession Version	NM_022776.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2244bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	oxysterol-binding protein-related protein 11
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA722217.1, DA112146.1, BX506747.1 and BC065213.1. On Aug 29, 2008 this sequence version replaced NM_022776.3. ##Evidence-Data-START## Transcript exon combination :: BC065213.1, SRR1803615.78789.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGGGGG GTGAACCAGT GTCCACAATG AAAGTCTCGG AGAGCGAAGG AAAGCTGGAG 
GGCCAGGCCA CAGCGGTGAC CCCGAACAAG AACAGCAGCT GTGGAGGTGG AATCAGTAGC 
AGCAGCAGCA GCCGCGGTGG CAGTGCAAAA GGCTGGCAGT ACAGTGATCA CATGGAAAAT 
GTGTATGGCT ATTTAATGAA GTATACCAAC CTTGTCACTG GGTGGCAGTA CAGGTTTTTT 
GTTTTAAACA ATGAAGCTGG GCTGTTGGAG TACTTTGTGA ATGAACAGTC TAGAAATCAG 
AAACCTAGAG GAACTTTGCA GCTTGCAGGA GCTGTAATAT CACCCAGTGA TGAGGATTCT 
CACACCTTCA CTGTAAACGC TGCCAGTGGG GAACAATATA AACTCAGAGC TACAGATGCA 
AAAGAGCGAC AGCACTGGGT TAGCAGACTT CAGATATGTA CACAGCATCA TACTGAAGCT 
ATTGGAAAGA ATAATCCTCC TCTGAAGTCA CGGAGCTTCT CACTTGCATC TAGTAGTAAT 
TCTCCTATAT CGCAGAGGAG ACCAAGTCAA AATGCCATTT CTTTTTTTAA TGTTGGACAT 
TCCAAACTGC AATCACTGAG CAAAAGAACT AATTTACCTC CAGACCATCT TGTGGAAGTC 
AGAGAAATGA TGTCTCATGC TGAAGGACAA CAAAGAGACT TAATTAGACG AATTGAATGC 
CTTCCTACTT CTGGCCATCT TAGTTCCTTG GACCAGGATC TCTTAATGCT CAAAGCTACT 
TCCATGGCAA CTATGAACTG CTTAAATGAC TGCTTTCATA TTCTCCAGTT ACAGCATGCA 
TCACATCAGA AGGGCTCATT GCCTTCAGGA ACGACAATCG AGTGGTTAGA ACCAAAGATA 
TCTTTATCAA ACCACTATAA AAATGGAGCT GACCAGCCCT TTGCAACTGA TCAGAGTAAG 
CCGGTGGCAG TCCCAGAAGA GCAGCCTGTT GCAGAATCTG GACTATTAGC GAGGGAGCCT 
GAAGAAATAA ATGCAGATGA TGAGATAGAG GATACATGTG ACCACAAAGA GGATGACCTG 
GGAGCTGTAG AAGAACAACG TAGTGTCATC CTACATCTCT TGTCACAGCT TAAGCTGGGC 
ATGGATTTAA CAAGAGTGGT GCTTCCTACA TTTATCCTAG AGAAGCGTTC CTTGCTGGAA 
ATGTATGCAG ACTTTATGTC TCATCCAGAC CTATTTATAG CCATCACTAA TGGAGCCACA 
GCTGAGGACA GAATGATTCG CTTTGTTGAG TACTACCTTA CCTCATTTCA TGAAGGCCGT 
AAGGGAGCCA TTGCTAAAAA ACCATACAAT CCTATCATTG GAGAAACATT TCACTGTTCC 
TGGAAGATGC CAAAAAGCGA GGTAGCATCC AGTGTTTTTA GCAGTTCTTC CACCCAGGGA 
GTCACAAATC ATGCTCCTTT ATCGGGGGAG TCTTTGACCC AGGTGGGATC AGACTGTTAC 
ACAGTCAGAT TTGTTGCTGA GCAGGTTTCT CATCATCCTC CAGTCTCAGG ATTTTATGCA 
GAATGTACAG AGAGGAAGAT GTGTGTAAAT GCGCATGTCT GGACTAAGAG CAAGTTCTTA 
GGCATGTCAA TAGGCGTGAC AATGGTTGGA GAAGGTATCC TTAGTCTGTT GGAGCATGGA 
GAAGAGTACA CATTTTCTCT ACCCTGTGCA TATGCTCGGT CAATTTTGAC TGTTCCTTGG 
GTAGAACTGG GTGGCAAAGT CAGTGTCAAC TGTGCAAAAA CTGGATATTC AGCCAGCATC 
ACTTTTCATA CCAAGCCATT TTATGGTGGC AAACTGCATC GGGTTACAGC TGAAGTAAAG 
CACAACATCA CCAACACTGT GGTATGCAGA GTGCAAGGGG AATGGAATAG TGTTCTTGAG 
TTCACATATA GCAATGGAGA GACAAAGTAT GTGGACTTGA CTAAATTGGC AGTGACGAAG 
AAAAGAGTGA GACCTCTGGA GAAGCAGGAT CCATTTGAAT CCAGGCGATT GTGGAAAAAT 
GTGACAGACT CGCTGAGAGA ATCTGAAATT GATAAGGCCA CAGAGCATAA GCATACCCTG 
GAAGAACGTC AGAGGACTGA AGAAAGGCAT CGTACTGAAA CAGGCACACC TTGGAAAACC 
AAATATTTTA TTAAAGAGGG AGATGGCTGG GTTTATCATA AACCACTTTG GAAAATAATT 
CCAACAACAC AACCAGCAGA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_073613.2
CDS	738..2981
Translation	MQGGEPVSTMKVSESEGKLEGQATAVTPNKNSSCGGGISSSSSSRGGSAKGWQYSDHMENVYGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSSNSPISQRRPSQNAISFFNVGHSKLQSLSKRTNLPPDHLVEVREMMSHAEGQQRDLIRRIECLPTSGHLSSLDQDLLMLKATSMATMNCLNDCFHILQLQHASHQKGSLPSGTTIEWLEPKISLSNHYKNGADQPFATDQSKPVAVPEEQPVAESGLLAREPEEINADDEIEDTCDHKEDDLGAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEFTYSNGETKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWKIIPTTQPAE

Target ORF information:

RefSeq Version	NM_022776.4
Organism	Homo sapiens(human)
Definition	Homo sapiens oxysterol binding protein like 11 (OSBPL11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022776.4

ORF Insert Sequence:

ATGCAGGGGG GTGAACCAGT GTCCACAATG AAAGTCTCGG AGAGCGAAGG AAAGCTGGAG 
GGCCAGGCCA CAGCGGTGAC CCCGAACAAG AACAGCAGCT GTGGAGGTGG AATCAGTAGC 
AGCAGCAGCA GCCGCGGTGG CAGTGCAAAA GGCTGGCAGT ACAGTGATCA CATGGAAAAT 
GTGTATGGCT ATTTAATGAA GTATACCAAC CTTGTCACTG GGTGGCAGTA CAGGTTTTTT 
GTTTTAAACA ATGAAGCTGG GCTGTTGGAG TACTTTGTGA ATGAACAGTC TAGAAATCAG 
AAACCTAGAG GAACTTTGCA GCTTGCAGGA GCTGTAATAT CACCCAGTGA TGAGGATTCT 
CACACCTTCA CTGTAAACGC TGCCAGTGGG GAACAATATA AACTCAGAGC TACAGATGCA 
AAAGAGCGAC AGCACTGGGT TAGCAGACTT CAGATATGTA CACAGCATCA TACTGAAGCT 
ATTGGAAAGA ATAATCCTCC TCTGAAGTCA CGGAGCTTCT CACTTGCATC TAGTAGTAAT 
TCTCCTATAT CGCAGAGGAG ACCAAGTCAA AATGCCATTT CTTTTTTTAA TGTTGGACAT 
TCCAAACTGC AATCACTGAG CAAAAGAACT AATTTACCTC CAGACCATCT TGTGGAAGTC 
AGAGAAATGA TGTCTCATGC TGAAGGACAA CAAAGAGACT TAATTAGACG AATTGAATGC 
CTTCCTACTT CTGGCCATCT TAGTTCCTTG GACCAGGATC TCTTAATGCT CAAAGCTACT 
TCCATGGCAA CTATGAACTG CTTAAATGAC TGCTTTCATA TTCTCCAGTT ACAGCATGCA 
TCACATCAGA AGGGCTCATT GCCTTCAGGA ACGACAATCG AGTGGTTAGA ACCAAAGATA 
TCTTTATCAA ACCACTATAA AAATGGAGCT GACCAGCCCT TTGCAACTGA TCAGAGTAAG 
CCGGTGGCAG TCCCAGAAGA GCAGCCTGTT GCAGAATCTG GACTATTAGC GAGGGAGCCT 
GAAGAAATAA ATGCAGATGA TGAGATAGAG GATACATGTG ACCACAAAGA GGATGACCTG 
GGAGCTGTAG AAGAACAACG TAGTGTCATC CTACATCTCT TGTCACAGCT TAAGCTGGGC 
ATGGATTTAA CAAGAGTGGT GCTTCCTACA TTTATCCTAG AGAAGCGTTC CTTGCTGGAA 
ATGTATGCAG ACTTTATGTC TCATCCAGAC CTATTTATAG CCATCACTAA TGGAGCCACA 
GCTGAGGACA GAATGATTCG CTTTGTTGAG TACTACCTTA CCTCATTTCA TGAAGGCCGT 
AAGGGAGCCA TTGCTAAAAA ACCATACAAT CCTATCATTG GAGAAACATT TCACTGTTCC 
TGGAAGATGC CAAAAAGCGA GGTAGCATCC AGTGTTTTTA GCAGTTCTTC CACCCAGGGA 
GTCACAAATC ATGCTCCTTT ATCGGGGGAG TCTTTGACCC AGGTGGGATC AGACTGTTAC 
ACAGTCAGAT TTGTTGCTGA GCAGGTTTCT CATCATCCTC CAGTCTCAGG ATTTTATGCA 
GAATGTACAG AGAGGAAGAT GTGTGTAAAT GCGCATGTCT GGACTAAGAG CAAGTTCTTA 
GGCATGTCAA TAGGCGTGAC AATGGTTGGA GAAGGTATCC TTAGTCTGTT GGAGCATGGA 
GAAGAGTACA CATTTTCTCT ACCCTGTGCA TATGCTCGGT CAATTTTGAC TGTTCCTTGG 
GTAGAACTGG GTGGCAAAGT CAGTGTCAAC TGTGCAAAAA CTGGATATTC AGCCAGCATC 
ACTTTTCATA CCAAGCCATT TTATGGTGGC AAACTGCATC GGGTTACAGC TGAAGTAAAG 
CACAACATCA CCAACACTGT GGTATGCAGA GTGCAAGGGG AATGGAATAG TGTTCTTGAG 
TTCACATATA GCAATGGAGA GACAAAGTAT GTGGACTTGA CTAAATTGGC AGTGACGAAG 
AAAAGAGTGA GACCTCTGGA GAAGCAGGAT CCATTTGAAT CCAGGCGATT GTGGAAAAAT 
GTGACAGACT CGCTGAGAGA ATCTGAAATT GATAAGGCCA CAGAGCATAA GCATACCCTG 
GAAGAACGTC AGAGGACTGA AGAAAGGCAT CGTACTGAAA CAGGCACACC TTGGAAAACC 
AAATATTTTA TTAAAGAGGG AGATGGCTGG GTTTATCATA AACCACTTTG GAAAATAATT 
CCAACAACAC AACCAGCAGA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

OSBP-related proteins (ORPs) in human adipose depots and cultured adipocytes: evidence for impacts on the adipocyte phenotype.
PloS one7(9)e45352(2012)
Zhou Y,Robciuc MR,Wabitsch M,Juuti A,Leivonen M,Ehnholm C,Yki-J?rvinen H,Olkkonen VM

OSBP-related protein 11 (ORP11) dimerizes with ORP9 and localizes at the Golgi-late endosome interface.
Experimental cell research316(19)3304-16(2010 Nov)
Zhou Y,Li S,M?yr?np?? MI,Zhong W,B?ck N,Yan D,Olkkonen VM

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Diabetes care33(10)2250-3(2010 Oct)
Bailey SD,Xie C,Do R,Montpetit A,Diaz R,Mohan V,Keavney B,Yusuf S,Gerstein HC,Engert JC,Anand S,

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
American journal of human genetics85(5)628-42(2009 Nov)
Talmud PJ,Drenos F,Shah S,Shah T,Palmen J,Verzilli C,Gaunt TR,Pallas J,Lovering R,Li K,Casas JP,Sofat R,Kumari M,Rodriguez S,Johnson T,Newhouse SJ,Dominiczak A,Samani NJ,Caulfield M,Sever P,Stanton A,Shields DC,Padmanabhan S,Melander O,Hastie C,Delles C,Ebrahim S,Marmot MG,Smith GD,Lawlor DA,Munroe PB,Day IN,Kivimaki M,Whittaker J,Humphries SE,Hingorani AD,,,

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OSBPL11 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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