LRRC37B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LRRC37B
Entrez Gene ID	114659
Full Name	leucine rich repeat containing 37B
Synonyms	LRRC37
General protein information	Preferred Names leucine rich repeat containing 37B Names leucine-rich repeat-containing protein 37B C66 SLIT-like testicular protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q11.2
Disorder MIM:	616558

mRNA and Protein(s)

mRNA	Protein	Name
NM_001321350.2	NP_001308279.1	leucine-rich repeat-containing protein 37B isoform 2
NM_001321350.1	NP_001308279.1	leucine-rich repeat-containing protein 37B isoform 2
NM_052888.2	NP_443120.2	leucine-rich repeat-containing protein 37B isoform 1 precursor
NM_052888.3	NP_443120.2	leucine-rich repeat-containing protein 37B isoform 1 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LRRC37B	XP_001172119.2
Homo sapiens (human)	LRRC37B	NP_443120.2

Gene Ontology
Bibliography

Related articles in PubMed

Evolutionary dynamism of the primate LRRC37 gene family.
Giannuzzi G, Siswara P, Malig M, Marques-Bonet T, , Mullikin JC, Ventura M, Eichler EE
Genome research23(1)46-59(2013 Jan)

Hundreds of variants clustered in genomic loci and biological pathways affect human height.
Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, Segr? AV, Speliotes EK, Wheeler E, Soranzo N, Park JH, Yang J, Gudbjartsson D, Heard-Costa NL, Randall JC, Qi L, Vernon Smith A, M?gi R, Pastinen T, Liang L, Heid IM, Luan J, Thorleifsson G, Winkler TW, Goddard ME, Sin Lo K, Palmer C, Workalemahu T, Aulchenko YS, Johansson A, Zillikens MC, Feitosa MF, Esko T, Johnson T, Ketkar S, Kraft P, Mangino M, Prokopenko I, Absher D, Albrecht E, Ernst F, Glazer NL, Hayward C, Hottenga JJ, Jacobs KB, Knowles JW, Kutalik Z, Monda KL, Polasek O, Preuss M, Rayner NW, Robertson NR, Steinthorsdottir V, Tyrer JP, Voight BF, Wiklund F, Xu J, Zhao JH, Nyholt DR, Pellikka N, Perola M, Perry JR, Surakka I, Tammesoo ML, Altmaier EL, Amin N, Aspelund T, Bhangale T, Boucher G, Chasman DI, Chen C, Coin L, Cooper MN, Dixon AL, Gibson Q, Grundberg E, Hao K, Juhani Junttila M, Kaplan LM, Kettunen J, K?nig IR, Kwan T, Lawrence RW, Levinson DF, Lorentzon M, McKnight B, Morris AP, M?ller M, Suh Ngwa J, Purcell S, Rafelt S, Salem RM, Salvi E, Sanna S, Shi J, Sovio U, Thompson JR, Turchin MC, Vandenput L, Verlaan DJ, Vitart V, White CC, Ziegler A, Almgren P, Balmforth AJ, Campbell H, Citterio L, De Grandi A, Dominiczak A, Duan J, Elliott P, Elosua R, Eriksson JG, Freimer NB, Geus EJ, Glorioso N, Haiqing S, Hartikainen AL, Havulinna AS, Hicks AA, Hui J, Igl W, Illig T, Jula A, Kajantie E, Kilpel?inen TO, Koiranen M, Kolcic I, Koskinen S, Kovacs P, Laitinen J, Liu J, Lokki ML, Marusic A, Maschio A, Meitinger T, Mulas A, Par? G, Parker AN, Peden JF, Petersmann A, Pichler I, Pietil?inen KH, Pouta A, Ridderstr?le M, Rotter JI, Sambrook JG, Sanders AR, Schmidt CO, Sinisalo J, Smit JH, Stringham HM, Bragi Walters G, Widen E, Wild SH, Willemsen G, Zagato L, Zgaga L, Zitting P, Alavere H, Farrall M, McArdle WL, Nelis M, Peters MJ, Ripatti S, van Meurs JB, Aben KK, Ardlie KG, Beckmann JS, Beilby JP, Bergman RN, Bergmann S, Collins FS, Cusi D, den Heijer M, Eiriksdottir G, Gejman PV, Hall AS, Hamsten A, Huikuri HV, Iribarren C, K?h?nen M, Kaprio J, Kathiresan S, Kiemeney L, Kocher T, Launer LJ, Lehtim?ki T, Melander O, Mosley TH Jr, Musk AW, Nieminen MS, O'Donnell CJ, Ohlsson C, Oostra B, Palmer LJ, Raitakari O, Ridker PM, Rioux JD, Rissanen A, Rivolta C, Schunkert H, Shuldiner AR, Siscovick DS, Stumvoll M, T?njes A, Tuomilehto J, van Ommen GJ, Viikari J, Heath AC, Martin NG, Montgomery GW, Province MA, Kayser M, Arnold AM, Atwood LD, Boerwinkle E, Chanock SJ, Deloukas P, Gieger C, Gr?nberg H, Hall P, Hattersley AT, Hengstenberg C, Hoffman W, Lathrop GM, Salomaa V, Schreiber S, Uda M, Waterworth D, Wright AF, Assimes TL, Barroso I, Hofman A, Mohlke KL, Boomsma DI, Caulfield MJ, Cupples LA, Erdmann J, Fox CS, Gudnason V, Gyllensten U, Harris TB, Hayes RB, Jarvelin MR, Mooser V, Munroe PB, Ouwehand WH, Penninx BW, Pramstaller PP, Quertermous T, Rudan I, Samani NJ, Spector TD, V?lzke H, Watkins H, Wilson JF, Groop LC, Haritunians T, Hu FB, Kaplan RC, Metspalu A, North KE, Schlessinger D, Wareham NJ, Hunter DJ, O'Connell JR, Strachan DP, Wichmann HE, Borecki IB, van Duijn CM, Schadt EE, Thorsteinsdottir U, Peltonen L, Uitterlinden AG, Visscher PM, Chatterjee N, Loos RJ, Boehnke M, McCarthy MI, Ingelsson E, Lindgren CM, Abecasis GR, Stefansson K, Frayling TM, Hirschhorn JN
Nature467(7317)832-8(2010 Oct)

RNF135 mutations are not present in patients with Sotos syndrome-like features.
Visser R, Koelma N, Vijfhuizen L, van der Wielen MJ, Kant SG, Breuning MH, Wit JM, Losekoot M
American journal of medical genetics. Part A149A(4)806-8(2009 Feb)

Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth.
Douglas J, Cilliers D, Coleman K, Tatton-Brown K, Barker K, Bernhard B, Burn J, Huson S, Josifova D, Lacombe D, Malik M, Mansour S, Reid E, Cormier-Daire V, Cole T, , Rahman N
Nature genetics39(8)963-5(2007 Aug)

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
Zody MC, Garber M, Adams DJ, Sharpe T, Harrow J, Lupski JR, Nicholson C, Searle SM, Wilming L, Young SK, Abouelleil A, Allen NR, Bi W, Bloom T, Borowsky ML, Bugalter BE, Butler J, Chang JL, Chen CK, Cook A, Corum B, Cuomo CA, de Jong PJ, DeCaprio D, Dewar K, FitzGerald M, Gilbert J, Gibson R, Gnerre S, Goldstein S, Grafham DV, Grocock R, Hafez N, Hagopian DS, Hart E, Norman CH, Humphray S, Jaffe DB, Jones M, Kamal M, Khodiyar VK, LaButti K, Laird G, Lehoczky J, Liu X, Lokyitsang T, Loveland J, Lui A, Macdonald P, Major JE, Matthews L, Mauceli E, McCarroll SA, Mihalev AH, Mudge J, Nguyen C, Nicol R, O'Leary SB, Osoegawa K, Schwartz DC, Shaw-Smith C, Stankiewicz P, Steward C, Swarbreck D, Venkataraman V, Whittaker CA, Yang X, Zimmer AR, Bradley A, Hubbard T, Birren BW, Rogers J, Lander ES, Nusbaum C
Nature440(7087)1045-9(2006 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: RNF135 mutations are not present in patients with Sotos syndrome-like features.

The following LRRC37B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LRRC37B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu74752	NM_001321350.2 Latest version!	Homo sapiens leucine rich repeat containing 37B (LRRC37B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu05552	NM_052888.3 Latest version!	Homo sapiens leucine rich repeat containing 37B (LRRC37B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
View Old Accession Versions >>
OHu74752	NM_001321350.1	Homo sapiens leucine rich repeat containing 37B (LRRC37B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu05552	NM_052888.2	Homo sapiens leucine rich repeat containing 37B (LRRC37B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$657.30 $939.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LRRC37B ( NM_052888.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_443120.2 Homo sapiens leucine rich repeat containing 37B (LRRC37B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu05552
Clone ID Related Accession (Same CDS sequence)	NM_052888.2 , NM_052888.3
Accession Version	NM_052888.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2844bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 37B isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BF979626.1, AY386261.1, AJ314647.1 and BM718301.1. On or before Mar 4, 2006 this sequence version replaced XM_945972.1, XM_942443.1, XM_945973.1, XM_945974.1, NM_052888.1. Transcript Variant: This variant (1) represents the shorter transcript and encodes the longer isoform (1), which contains a predicted signal peptide. ##Evidence-Data-START## Transcript exon combination :: AJ314647.1, AK302740.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTTGGC TGCGTTTCTG GGGCCCATGG CCCCTCCTTA CGTGGCAACT ATTGTCTTTA 
CTAGTCAAGG AGGCTCAGCC TCTGGTGTGG GTCAAGGACC CGCTCCAGCT GACCTCTAAC 
CCCCTGGGGC CACCTGAGCC CTGGTCTTCC CGCTCCTCCC ATCTCCCATG GGAATCTCCC 
CATGCACCTG CTCCCCCAGC AGCCCCGGGG GACTTTGATT ACCTGGGGCC CTCTGCTTCT 
TCGCAGATGT CAGCCCTGCC TCAGGAACCA ACTGAAAATT TGGCTCCATT CCTGAAGGAA 
TTGGATTCAG CTGGAGAGCT GCCCCTGGGG CCAGAGCCGT TCTTGGCTGC ACATCAGGAC 
TTAAATGACA AGCGGACTCC AGAAGAAAGG CTCCCAGAGG TGGTTCCGCT TCTCAACCGG 
GATCAGAACC AGGCCCTAGT TCAGCTTCCT CGCCTCAAGT GGGTTCAAAC TACAGATCTA 
GATCGGGCTG CAGGTCATCA GGCAGATGAA ATACTTGTTC CACTAGACAG TAAGGTTTCA 
AGACCAACCA AATTTGTTGT TTCGCCCAAG AACCTGAAGA AAGATCTAGC TGAACGTTGG 
AGCCTTCCTG AGATTGTTGG GATTCCACAC CAATTATCCA AACCTCAGCG TCAGAAACAG 
ACTTTGCCAG ATGATTATTT GAGTATGGAC ACACTGTATC CCGGCAGCCT ACCTCCAGAA 
CTCCGGGTGA ACGCAGATGA GCCTCCAGGG CCTCCTGAGC AAGTTGGACT TTCTCAATTC 
CATCTAGAGC CCAAAAGTCA AAATCCAGAG ACCCTTGAAG ACATCCAGTC CTCTTCACTC 
CAGGAAGAAG CCCCAGCGCA GCTTCTACAG CTCCCTCAGG AGGTAGAACC TTCAACCCAG 
CAGGAGGCCC CAGCTCTGCC TCCAGAGTCC TCTATGGAGA GTCTAGCTCA AACTCCACTG 
AATCATGAAG TGACAGTTCA ACCTCCAGGT GAGGATCAAG CTCATTATAA TTTGCCCAAG 
TTTACAGTCA AACCTGCAGA TGTGGAGGTT ACCATGACTT CAGAGCCTAA AAATGAGACA 
GAATCTACCC AAGCCCAGCA GGAGGCCCCA ATTCAGCCTC CCGAGGAGGC GGAACCTTCT 
TCTACAGCCC TGAGGACTAC AGATCCTCCT CCAGAACACC CTGAGGTGAC ACTTCCACCT 
TCAGACAAGG GTCAGGCTCA GCATTCACAC CTGACTGAAG CCACAGTTCA ACCTCTGGAC 
CTGGAGCTTA GCATAACTAC AGAGCCTACT ACAGAGGTTA AACCGTCTCC AACCACGGAG 
GAAACCTCAG CTCAGCCTCC AGACCCGGGG CTTGCCATAA CTCCAGAACC CACTACAGAG 
ATTGGACATT CCACAGCCCT GGAGAAGACT AGAGCTCCTC ATCCAGACCA GGTTCAGACT 
CTGCATCGAA GCCTGACTGA AGTCACAGGT CCACCTACAA AGTTAGAATC TTCGCAGGAT 
TCATTGGTGC AGTCTGAAAC TGCACCAGAG GAACAGAAGG CCTCCACAAG CACCAACATA 
TGTGAGCTCT GCACCTGCGG AGATGAGACT CTGTCATGTG TTGGTCTCAG CCCAAAGCAG 
AGGCTCCGCC AAGTGCCTGT GCCAGAGCCC GACACCTACA ATGGCATCTT CACCACCTTA 
AATTTCCAAG GAAACTATAT TTCATACCTT GATGGAAATG TATGGAAAGC ATACAGTTGG 
ACCGAGAAAC TAATTCTCAG TGAAAATTAT TTGACTGAAT TACCTAAGGA TTCATTTGAA 
GGCCTGCTAT ACCTCCAGTA TTTAGATTTA TCCTGCAATA AAATACGATA TATTGAAAGA 
CAAACATTTG AATCACTACC ATTTTTGCAG TATATAAATC TGGGCTGCAA TTTAATTACA 
AAACTGAGCC TTGGAACATT TCAGGCCTGG CACGGAATGC AGTTTTTACA CAACTTAATT 
CTCAATCGCA ATCCTCTGAC TACTGTCGAA GATCCATATC TCTTTGAACT GCCGGCATTA 
AAATATCTAG ACATGGGAAC AACACACATC ACACTTACAA CACTTAAGAA CATTCTCACG 
ATGACTGTTG AACTGGAAAA ACTGATCTTA CCTAGCCATA TGGCCTGCTG CCTCTGCCAA 
TTTAAAAATA GCATTGAGGC TGTCTGCAAG ACAGTCAAGC TGCATTGCAA CACTGCATGT 
CTGACTAACA GCATACATTG TCCTGAAGAA GCATCTGTAG GGAATCCAGA AGGAGCGTTC 
ATGAAGATGT TACAAGCCCG GAAGCAGCAC ATGAGCACTC AGCTGACTAT TGAGTCGGAG 
GCGCCCTCAG ACAGCAGTGG CATCAACTTG TCAGGCTTTG GGGGTGATCA GCTTGAAATT 
CAGCTAACCG AGCAGCTACG GTCCCTCATC CCCAACGAGG ATGTGAGAAA GTTCATGTCT 
CATGTTATCC GGACCTTGAA AATGGAATGT TCAGAAACAC ATGTGCAAGG GAGCTGTGCC 
AAGCTCATGT TGCGAACAGG CCTCCTGATG AAGCTTCTCA GCGAGCAGCA GGAAGCAAAG 
GCATTGAATG TAGAATGGGA TACGGACCAA CAAAAAACAA ATTATATTAA TGAGAACATG 
GAACAGAATG AACAGAAAGA GCAGAAGTCA AGTGAGCTCA TGAAAGAAGT TCCAGGAGAT 
GACTATAAGA ACAAACTCAT CTTCGCAATA TCTGTGACTG TAATACTAAT AATTTTGATT 
ATAATTTTTT GTCTTATAGA GGTGAATTCA CATAAAAGGG CATCAGAAAA ATACAAAGAC 
AACCCATCAA TATCAGGAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_443120.2
CDS	12..2855
Translation	MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSSRSSHLPWESPHAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKELDSAGELPLGPEPFLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSKVSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQQEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTSTNICELCTCGDETLSCVGLSPKQRLRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILTMTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNTACLTNSIHCPEEASVGNPEGAFMKMLQARKQHMSTQLTIESEAPSDSSGINLSGFGGDQLEIQLTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCAKLMLRTGLLMKLLSEQQEAKALNVEWDTDQQKTNYINENMEQNEQKEQKSSELMKEVPGDDYKNKLIFAISVTVILIILIIIFCLIEVNSHKRASEKYKDNPSISGA

Target ORF information:

RefSeq Version	NM_052888.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 37B (LRRC37B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_052888.2

ORF Insert Sequence:

ATGTCTTGGC TGCGTTTCTG GGGCCCATGG CCCCTCCTTA CGTGGCAACT ATTGTCTTTA 
CTAGTCAAGG AGGCTCAGCC TCTGGTGTGG GTCAAGGACC CGCTCCAGCT GACCTCTAAC 
CCCCTGGGGC CACCTGAGCC CTGGTCTTCC CGCTCCTCCC ATCTCCCATG GGAATCTCCC 
CATGCACCTG CTCCCCCAGC AGCCCCGGGG GACTTTGATT ACCTGGGGCC CTCTGCTTCT 
TCGCAGATGT CAGCCCTGCC TCAGGAACCA ACTGAAAATT TGGCTCCATT CCTGAAGGAA 
TTGGATTCAG CTGGAGAGCT GCCCCTGGGG CCAGAGCCGT TCTTGGCTGC ACATCAGGAC 
TTAAATGACA AGCGGACTCC AGAAGAAAGG CTCCCAGAGG TGGTTCCGCT TCTCAACCGG 
GATCAGAACC AGGCCCTAGT TCAGCTTCCT CGCCTCAAGT GGGTTCAAAC TACAGATCTA 
GATCGGGCTG CAGGTCATCA GGCAGATGAA ATACTTGTTC CACTAGACAG TAAGGTTTCA 
AGACCAACCA AATTTGTTGT TTCGCCCAAG AACCTGAAGA AAGATCTAGC TGAACGTTGG 
AGCCTTCCTG AGATTGTTGG GATTCCACAC CAATTATCCA AACCTCAGCG TCAGAAACAG 
ACTTTGCCAG ATGATTATTT GAGTATGGAC ACACTGTATC CCGGCAGCCT ACCTCCAGAA 
CTCCGGGTGA ACGCAGATGA GCCTCCAGGG CCTCCTGAGC AAGTTGGACT TTCTCAATTC 
CATCTAGAGC CCAAAAGTCA AAATCCAGAG ACCCTTGAAG ACATCCAGTC CTCTTCACTC 
CAGGAAGAAG CCCCAGCGCA GCTTCTACAG CTCCCTCAGG AGGTAGAACC TTCAACCCAG 
CAGGAGGCCC CAGCTCTGCC TCCAGAGTCC TCTATGGAGA GTCTAGCTCA AACTCCACTG 
AATCATGAAG TGACAGTTCA ACCTCCAGGT GAGGATCAAG CTCATTATAA TTTGCCCAAG 
TTTACAGTCA AACCTGCAGA TGTGGAGGTT ACCATGACTT CAGAGCCTAA AAATGAGACA 
GAATCTACCC AAGCCCAGCA GGAGGCCCCA ATTCAGCCTC CCGAGGAGGC GGAACCTTCT 
TCTACAGCCC TGAGGACTAC AGATCCTCCT CCAGAACACC CTGAGGTGAC ACTTCCACCT 
TCAGACAAGG GTCAGGCTCA GCATTCACAC CTGACTGAAG CCACAGTTCA ACCTCTGGAC 
CTGGAGCTTA GCATAACTAC AGAGCCTACT ACAGAGGTTA AACCGTCTCC AACCACGGAG 
GAAACCTCAG CTCAGCCTCC AGACCCGGGG CTTGCCATAA CTCCAGAACC CACTACAGAG 
ATTGGACATT CCACAGCCCT GGAGAAGACT AGAGCTCCTC ATCCAGACCA GGTTCAGACT 
CTGCATCGAA GCCTGACTGA AGTCACAGGT CCACCTACAA AGTTAGAATC TTCGCAGGAT 
TCATTGGTGC AGTCTGAAAC TGCACCAGAG GAACAGAAGG CCTCCACAAG CACCAACATA 
TGTGAGCTCT GCACCTGCGG AGATGAGACT CTGTCATGTG TTGGTCTCAG CCCAAAGCAG 
AGGCTCCGCC AAGTGCCTGT GCCAGAGCCC GACACCTACA ATGGCATCTT CACCACCTTA 
AATTTCCAAG GAAACTATAT TTCATACCTT GATGGAAATG TATGGAAAGC ATACAGTTGG 
ACCGAGAAAC TAATTCTCAG TGAAAATTAT TTGACTGAAT TACCTAAGGA TTCATTTGAA 
GGCCTGCTAT ACCTCCAGTA TTTAGATTTA TCCTGCAATA AAATACGATA TATTGAAAGA 
CAAACATTTG AATCACTACC ATTTTTGCAG TATATAAATC TGGGCTGCAA TTTAATTACA 
AAACTGAGCC TTGGAACATT TCAGGCCTGG CACGGAATGC AGTTTTTACA CAACTTAATT 
CTCAATCGCA ATCCTCTGAC TACTGTCGAA GATCCATATC TCTTTGAACT GCCGGCATTA 
AAATATCTAG ACATGGGAAC AACACACATC ACACTTACAA CACTTAAGAA CATTCTCACG 
ATGACTGTTG AACTGGAAAA ACTGATCTTA CCTAGCCATA TGGCCTGCTG CCTCTGCCAA 
TTTAAAAATA GCATTGAGGC TGTCTGCAAG ACAGTCAAGC TGCATTGCAA CACTGCATGT 
CTGACTAACA GCATACATTG TCCTGAAGAA GCATCTGTAG GGAATCCAGA AGGAGCGTTC 
ATGAAGATGT TACAAGCCCG GAAGCAGCAC ATGAGCACTC AGCTGACTAT TGAGTCGGAG 
GCGCCCTCAG ACAGCAGTGG CATCAACTTG TCAGGCTTTG GGGGTGATCA GCTTGAAATT 
CAGCTAACCG AGCAGCTACG GTCCCTCATC CCCAACGAGG ATGTGAGAAA GTTCATGTCT 
CATGTTATCC GGACCTTGAA AATGGAATGT TCAGAAACAC ATGTGCAAGG GAGCTGTGCC 
AAGCTCATGT TGCGAACAGG CCTCCTGATG AAGCTTCTCA GCGAGCAGCA GGAAGCAAAG 
GCATTGAATG TAGAATGGGA TACGGACCAA CAAAAAACAA ATTATATTAA TGAGAACATG 
GAACAGAATG AACAGAAAGA GCAGAAGTCA AGTGAGCTCA TGAAAGAAGT TCCAGGAGAT 
GACTATAAGA ACAAACTCAT CTTCGCAATA TCTGTGACTG TAATACTAAT AATTTTGATT 
ATAATTTTTT GTCTTATAGA GGTGAATTCA CATAAAAGGG CATCAGAAAA ATACAAAGAC 
AACCCATCAA TATCAGGAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC37B ( NM_001321350.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001308279.1 Homo sapiens leucine rich repeat containing 37B (LRRC37B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu74752
Clone ID Related Accession (Same CDS sequence)	NM_001321350.2 , NM_001321350.1
Accession Version	NM_001321350.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2598bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 37B isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC090616.13, DB475546.2, AK299772.1 and AK302740.1. On Jun 2, 2019 this sequence version replaced NM_001321350.1. Transcript Variant: This variant (2) represents use of an upstream promoter, differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon compared to variant 1. The encoded isoform (2) lacks a predicted signal peptide compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK299772.1, SRR1803612.162222.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCAGCCC TGCCTCAGGA ACCAACTGAA AATTTGGCTC CATTCCTGAA GGAATTGGAT 
TCAGCTGGAG AGCTGCCCCT GGGGCCAGAG CCGTTCTTGG CTGCACATCA GGACTTAAAT 
GACAAGCGGA CTCCAGAAGA AAGGCTCCCA GAGGTGGTTC CGCTTCTCAA CCGGGATCAG 
AACCAGGCCC TAGTTCAGCT TCCTCGCCTC AAGTGGGTTC AAACTACAGA TCTAGATCGG 
GCTGCAGGTC ATCAGGCAGA TGAAATACTT GTTCCACTAG ACAGTAAGGT TTCAAGACCA 
ACCAAATTTG TTGTTTCGCC CAAGAACCTG AAGAAAGATC TAGCTGAACG TTGGAGCCTT 
CCTGAGATTG TTGGGATTCC ACACCAATTA TCCAAACCTC AGCGTCAGAA ACAGACTTTG 
CCAGATGATT ATTTGAGTAT GGACACACTG TATCCCGGCA GCCTACCTCC AGAACTCCGG 
GTGAACGCAG ATGAGCCTCC AGGGCCTCCT GAGCAAGTTG GACTTTCTCA ATTCCATCTA 
GAGCCCAAAA GTCAAAATCC AGAGACCCTT GAAGACATCC AGTCCTCTTC ACTCCAGGAA 
GAAGCCCCAG CGCAGCTTCT ACAGCTCCCT CAGGAGGTAG AACCTTCAAC CCAGCAGGAG 
GCCCCAGCTC TGCCTCCAGA GTCCTCTATG GAGAGTCTAG CTCAAACTCC ACTGAATCAT 
GAAGTGACAG TTCAACCTCC AGGTGAGGAT CAAGCTCATT ATAATTTGCC CAAGTTTACA 
GTCAAACCTG CAGATGTGGA GGTTACCATG ACTTCAGAGC CTAAAAATGA GACAGAATCT 
ACCCAAGCCC AGCAGGAGGC CCCAATTCAG CCTCCCGAGG AGGCGGAACC TTCTTCTACA 
GCCCTGAGGA CTACAGATCC TCCTCCAGAA CACCCTGAGG TGACACTTCC ACCTTCAGAC 
AAGGGTCAGG CTCAGCATTC ACACCTGACT GAAGCCACAG TTCAACCTCT GGACCTGGAG 
CTTAGCATAA CTACAGAGCC TACTACAGAG GTTAAACCGT CTCCAACCAC GGAGGAAACC 
TCAGCTCAGC CTCCAGACCC GGGGCTTGCC ATAACTCCAG AACCCACTAC AGAGATTGGA 
CATTCCACAG CCCTGGAGAA GACTAGAGCT CCTCATCCAG ACCAGGTTCA GACTCTGCAT 
CGAAGCCTGA CTGAAGTCAC AGGTCCACCT ACAAAGTTAG AATCTTCGCA GGATTCATTG 
GTGCAGTCTG AAACTGCACC AGAGGAACAG AAGGCCTCCA CAAGCACCAA CATATGTGAG 
CTCTGCACCT GCGGAGATGA GACTCTGTCA TGTGTTGGTC TCAGCCCAAA GCAGAGGCTC 
CGCCAAGTGC CTGTGCCAGA GCCCGACACC TACAATGGCA TCTTCACCAC CTTAAATTTC 
CAAGGAAACT ATATTTCATA CCTTGATGGA AATGTATGGA AAGCATACAG TTGGACCGAG 
AAACTAATTC TCAGTGAAAA TTATTTGACT GAATTACCTA AGGATTCATT TGAAGGCCTG 
CTATACCTCC AGTATTTAGA TTTATCCTGC AATAAAATAC GATATATTGA AAGACAAACA 
TTTGAATCAC TACCATTTTT GCAGTATATA AATCTGGGCT GCAATTTAAT TACAAAACTG 
AGCCTTGGAA CATTTCAGGC CTGGCACGGA ATGCAGTTTT TACACAACTT AATTCTCAAT 
CGCAATCCTC TGACTACTGT CGAAGATCCA TATCTCTTTG AACTGCCGGC ATTAAAATAT 
CTAGACATGG GAACAACACA CATCACACTT ACAACACTTA AGAACATTCT CACGATGACT 
GTTGAACTGG AAAAACTGAT CTTACCTAGC CATATGGCCT GCTGCCTCTG CCAATTTAAA 
AATAGCATTG AGGCTGTCTG CAAGACAGTC AAGCTGCATT GCAACACTGC ATGTCTGACT 
AACAGCATAC ATTGTCCTGA AGAAGCATCT GTAGGGAATC CAGAAGGAGC GTTCATGAAG 
ATGTTACAAG CCCGGAAGCA GCACATGAGC ACTCAGCTGA CTATTGAGTC GGAGGCGCCC 
TCAGACAGCA GTGGCATCAA CTTGTCAGGC TTTGGGGGTG ATCAGCTTGA AATTCAGCTA 
ACCGAGCAGC TACGGTCCCT CATCCCCAAC GAGGATGTGA GAAAGTTCAT GTCTCATGTT 
ATCCGGACCT TGAAAATGGA ATGTTCAGAA ACACATGTGC AAGGGAGCTG TGCCAAGCTC 
ATGTTGCGAA CAGGCCTCCT GATGAAGCTT CTCAGCGAGC AGCAGGAAGC AAAGGCATTG 
AATGTAGAAT GGGATACGGA CCAACAAAAA ACAAATTATA TTAATGAGAA CATGGAACAG 
AATGAACAGA AAGAGCAGAA GTCAAGTGAG CTCATGAAAG AAGTTCCAGG AGATGACTAT 
AAGAACAAAC TCATCTTCGC AATATCTGTG ACTGTAATAC TAATAATTTT GATTATAATT 
TTTTGTCTTA TAGAGGTGAA TTCACATAAA AGGGCATCAG AAAAATACAA AGACAACCCA 
TCAATATCAG GAGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001308279.1
CDS	941..3538
Translation	MSALPQEPTENLAPFLKELDSAGELPLGPEPFLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSKVSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQQEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTSTNICELCTCGDETLSCVGLSPKQRLRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILTMTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNTACLTNSIHCPEEASVGNPEGAFMKMLQARKQHMSTQLTIESEAPSDSSGINLSGFGGDQLEIQLTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCAKLMLRTGLLMKLLSEQQEAKALNVEWDTDQQKTNYINENMEQNEQKEQKSSELMKEVPGDDYKNKLIFAISVTVILIILIIIFCLIEVNSHKRASEKYKDNPSISGA

Target ORF information:

RefSeq Version	NM_001321350.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 37B (LRRC37B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321350.2

ORF Insert Sequence:

ATGTCAGCCC TGCCTCAGGA ACCAACTGAA AATTTGGCTC CATTCCTGAA GGAATTGGAT 
TCAGCTGGAG AGCTGCCCCT GGGGCCAGAG CCGTTCTTGG CTGCACATCA GGACTTAAAT 
GACAAGCGGA CTCCAGAAGA AAGGCTCCCA GAGGTGGTTC CGCTTCTCAA CCGGGATCAG 
AACCAGGCCC TAGTTCAGCT TCCTCGCCTC AAGTGGGTTC AAACTACAGA TCTAGATCGG 
GCTGCAGGTC ATCAGGCAGA TGAAATACTT GTTCCACTAG ACAGTAAGGT TTCAAGACCA 
ACCAAATTTG TTGTTTCGCC CAAGAACCTG AAGAAAGATC TAGCTGAACG TTGGAGCCTT 
CCTGAGATTG TTGGGATTCC ACACCAATTA TCCAAACCTC AGCGTCAGAA ACAGACTTTG 
CCAGATGATT ATTTGAGTAT GGACACACTG TATCCCGGCA GCCTACCTCC AGAACTCCGG 
GTGAACGCAG ATGAGCCTCC AGGGCCTCCT GAGCAAGTTG GACTTTCTCA ATTCCATCTA 
GAGCCCAAAA GTCAAAATCC AGAGACCCTT GAAGACATCC AGTCCTCTTC ACTCCAGGAA 
GAAGCCCCAG CGCAGCTTCT ACAGCTCCCT CAGGAGGTAG AACCTTCAAC CCAGCAGGAG 
GCCCCAGCTC TGCCTCCAGA GTCCTCTATG GAGAGTCTAG CTCAAACTCC ACTGAATCAT 
GAAGTGACAG TTCAACCTCC AGGTGAGGAT CAAGCTCATT ATAATTTGCC CAAGTTTACA 
GTCAAACCTG CAGATGTGGA GGTTACCATG ACTTCAGAGC CTAAAAATGA GACAGAATCT 
ACCCAAGCCC AGCAGGAGGC CCCAATTCAG CCTCCCGAGG AGGCGGAACC TTCTTCTACA 
GCCCTGAGGA CTACAGATCC TCCTCCAGAA CACCCTGAGG TGACACTTCC ACCTTCAGAC 
AAGGGTCAGG CTCAGCATTC ACACCTGACT GAAGCCACAG TTCAACCTCT GGACCTGGAG 
CTTAGCATAA CTACAGAGCC TACTACAGAG GTTAAACCGT CTCCAACCAC GGAGGAAACC 
TCAGCTCAGC CTCCAGACCC GGGGCTTGCC ATAACTCCAG AACCCACTAC AGAGATTGGA 
CATTCCACAG CCCTGGAGAA GACTAGAGCT CCTCATCCAG ACCAGGTTCA GACTCTGCAT 
CGAAGCCTGA CTGAAGTCAC AGGTCCACCT ACAAAGTTAG AATCTTCGCA GGATTCATTG 
GTGCAGTCTG AAACTGCACC AGAGGAACAG AAGGCCTCCA CAAGCACCAA CATATGTGAG 
CTCTGCACCT GCGGAGATGA GACTCTGTCA TGTGTTGGTC TCAGCCCAAA GCAGAGGCTC 
CGCCAAGTGC CTGTGCCAGA GCCCGACACC TACAATGGCA TCTTCACCAC CTTAAATTTC 
CAAGGAAACT ATATTTCATA CCTTGATGGA AATGTATGGA AAGCATACAG TTGGACCGAG 
AAACTAATTC TCAGTGAAAA TTATTTGACT GAATTACCTA AGGATTCATT TGAAGGCCTG 
CTATACCTCC AGTATTTAGA TTTATCCTGC AATAAAATAC GATATATTGA AAGACAAACA 
TTTGAATCAC TACCATTTTT GCAGTATATA AATCTGGGCT GCAATTTAAT TACAAAACTG 
AGCCTTGGAA CATTTCAGGC CTGGCACGGA ATGCAGTTTT TACACAACTT AATTCTCAAT 
CGCAATCCTC TGACTACTGT CGAAGATCCA TATCTCTTTG AACTGCCGGC ATTAAAATAT 
CTAGACATGG GAACAACACA CATCACACTT ACAACACTTA AGAACATTCT CACGATGACT 
GTTGAACTGG AAAAACTGAT CTTACCTAGC CATATGGCCT GCTGCCTCTG CCAATTTAAA 
AATAGCATTG AGGCTGTCTG CAAGACAGTC AAGCTGCATT GCAACACTGC ATGTCTGACT 
AACAGCATAC ATTGTCCTGA AGAAGCATCT GTAGGGAATC CAGAAGGAGC GTTCATGAAG 
ATGTTACAAG CCCGGAAGCA GCACATGAGC ACTCAGCTGA CTATTGAGTC GGAGGCGCCC 
TCAGACAGCA GTGGCATCAA CTTGTCAGGC TTTGGGGGTG ATCAGCTTGA AATTCAGCTA 
ACCGAGCAGC TACGGTCCCT CATCCCCAAC GAGGATGTGA GAAAGTTCAT GTCTCATGTT 
ATCCGGACCT TGAAAATGGA ATGTTCAGAA ACACATGTGC AAGGGAGCTG TGCCAAGCTC 
ATGTTGCGAA CAGGCCTCCT GATGAAGCTT CTCAGCGAGC AGCAGGAAGC AAAGGCATTG 
AATGTAGAAT GGGATACGGA CCAACAAAAA ACAAATTATA TTAATGAGAA CATGGAACAG 
AATGAACAGA AAGAGCAGAA GTCAAGTGAG CTCATGAAAG AAGTTCCAGG AGATGACTAT 
AAGAACAAAC TCATCTTCGC AATATCTGTG ACTGTAATAC TAATAATTTT GATTATAATT 
TTTTGTCTTA TAGAGGTGAA TTCACATAAA AGGGCATCAG AAAAATACAA AGACAACCCA 
TCAATATCAG GAGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC37B ( NM_001321350.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001308279.1 Homo sapiens leucine rich repeat containing 37B (LRRC37B), transcript variant 2, mRNA.

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CloneID	OHu74752
Clone ID Related Accession (Same CDS sequence)	NM_001321350.2 , NM_001321350.1
Accession Version	NM_001321350.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2598bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-30
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 37B isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB475546.2, AK299772.1, AK302740.1 and AI336678.1. On Mar 23, 2016 this sequence version replaced XM_011524268.1. Transcript Variant: This variant (2) represents use of an upstream promoter, differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon compared to variant 1. The encoded isoform (2) lacks a predicted signal peptide compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK299772.1, SRR1803612.162222.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCAGCCC TGCCTCAGGA ACCAACTGAA AATTTGGCTC CATTCCTGAA GGAATTGGAT 
TCAGCTGGAG AGCTGCCCCT GGGGCCAGAG CCGTTCTTGG CTGCACATCA GGACTTAAAT 
GACAAGCGGA CTCCAGAAGA AAGGCTCCCA GAGGTGGTTC CGCTTCTCAA CCGGGATCAG 
AACCAGGCCC TAGTTCAGCT TCCTCGCCTC AAGTGGGTTC AAACTACAGA TCTAGATCGG 
GCTGCAGGTC ATCAGGCAGA TGAAATACTT GTTCCACTAG ACAGTAAGGT TTCAAGACCA 
ACCAAATTTG TTGTTTCGCC CAAGAACCTG AAGAAAGATC TAGCTGAACG TTGGAGCCTT 
CCTGAGATTG TTGGGATTCC ACACCAATTA TCCAAACCTC AGCGTCAGAA ACAGACTTTG 
CCAGATGATT ATTTGAGTAT GGACACACTG TATCCCGGCA GCCTACCTCC AGAACTCCGG 
GTGAACGCAG ATGAGCCTCC AGGGCCTCCT GAGCAAGTTG GACTTTCTCA ATTCCATCTA 
GAGCCCAAAA GTCAAAATCC AGAGACCCTT GAAGACATCC AGTCCTCTTC ACTCCAGGAA 
GAAGCCCCAG CGCAGCTTCT ACAGCTCCCT CAGGAGGTAG AACCTTCAAC CCAGCAGGAG 
GCCCCAGCTC TGCCTCCAGA GTCCTCTATG GAGAGTCTAG CTCAAACTCC ACTGAATCAT 
GAAGTGACAG TTCAACCTCC AGGTGAGGAT CAAGCTCATT ATAATTTGCC CAAGTTTACA 
GTCAAACCTG CAGATGTGGA GGTTACCATG ACTTCAGAGC CTAAAAATGA GACAGAATCT 
ACCCAAGCCC AGCAGGAGGC CCCAATTCAG CCTCCCGAGG AGGCGGAACC TTCTTCTACA 
GCCCTGAGGA CTACAGATCC TCCTCCAGAA CACCCTGAGG TGACACTTCC ACCTTCAGAC 
AAGGGTCAGG CTCAGCATTC ACACCTGACT GAAGCCACAG TTCAACCTCT GGACCTGGAG 
CTTAGCATAA CTACAGAGCC TACTACAGAG GTTAAACCGT CTCCAACCAC GGAGGAAACC 
TCAGCTCAGC CTCCAGACCC GGGGCTTGCC ATAACTCCAG AACCCACTAC AGAGATTGGA 
CATTCCACAG CCCTGGAGAA GACTAGAGCT CCTCATCCAG ACCAGGTTCA GACTCTGCAT 
CGAAGCCTGA CTGAAGTCAC AGGTCCACCT ACAAAGTTAG AATCTTCGCA GGATTCATTG 
GTGCAGTCTG AAACTGCACC AGAGGAACAG AAGGCCTCCA CAAGCACCAA CATATGTGAG 
CTCTGCACCT GCGGAGATGA GACTCTGTCA TGTGTTGGTC TCAGCCCAAA GCAGAGGCTC 
CGCCAAGTGC CTGTGCCAGA GCCCGACACC TACAATGGCA TCTTCACCAC CTTAAATTTC 
CAAGGAAACT ATATTTCATA CCTTGATGGA AATGTATGGA AAGCATACAG TTGGACCGAG 
AAACTAATTC TCAGTGAAAA TTATTTGACT GAATTACCTA AGGATTCATT TGAAGGCCTG 
CTATACCTCC AGTATTTAGA TTTATCCTGC AATAAAATAC GATATATTGA AAGACAAACA 
TTTGAATCAC TACCATTTTT GCAGTATATA AATCTGGGCT GCAATTTAAT TACAAAACTG 
AGCCTTGGAA CATTTCAGGC CTGGCACGGA ATGCAGTTTT TACACAACTT AATTCTCAAT 
CGCAATCCTC TGACTACTGT CGAAGATCCA TATCTCTTTG AACTGCCGGC ATTAAAATAT 
CTAGACATGG GAACAACACA CATCACACTT ACAACACTTA AGAACATTCT CACGATGACT 
GTTGAACTGG AAAAACTGAT CTTACCTAGC CATATGGCCT GCTGCCTCTG CCAATTTAAA 
AATAGCATTG AGGCTGTCTG CAAGACAGTC AAGCTGCATT GCAACACTGC ATGTCTGACT 
AACAGCATAC ATTGTCCTGA AGAAGCATCT GTAGGGAATC CAGAAGGAGC GTTCATGAAG 
ATGTTACAAG CCCGGAAGCA GCACATGAGC ACTCAGCTGA CTATTGAGTC GGAGGCGCCC 
TCAGACAGCA GTGGCATCAA CTTGTCAGGC TTTGGGGGTG ATCAGCTTGA AATTCAGCTA 
ACCGAGCAGC TACGGTCCCT CATCCCCAAC GAGGATGTGA GAAAGTTCAT GTCTCATGTT 
ATCCGGACCT TGAAAATGGA ATGTTCAGAA ACACATGTGC AAGGGAGCTG TGCCAAGCTC 
ATGTTGCGAA CAGGCCTCCT GATGAAGCTT CTCAGCGAGC AGCAGGAAGC AAAGGCATTG 
AATGTAGAAT GGGATACGGA CCAACAAAAA ACAAATTATA TTAATGAGAA CATGGAACAG 
AATGAACAGA AAGAGCAGAA GTCAAGTGAG CTCATGAAAG AAGTTCCAGG AGATGACTAT 
AAGAACAAAC TCATCTTCGC AATATCTGTG ACTGTAATAC TAATAATTTT GATTATAATT 
TTTTGTCTTA TAGAGGTGAA TTCACATAAA AGGGCATCAG AAAAATACAA AGACAACCCA 
TCAATATCAG GAGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001308279.1
CDS	452..3049
Translation	MSALPQEPTENLAPFLKELDSAGELPLGPEPFLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSKVSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQQEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTSTNICELCTCGDETLSCVGLSPKQRLRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILTMTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNTACLTNSIHCPEEASVGNPEGAFMKMLQARKQHMSTQLTIESEAPSDSSGINLSGFGGDQLEIQLTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCAKLMLRTGLLMKLLSEQQEAKALNVEWDTDQQKTNYINENMEQNEQKEQKSSELMKEVPGDDYKNKLIFAISVTVILIILIIIFCLIEVNSHKRASEKYKDNPSISGA

Target ORF information:

RefSeq Version	NM_001321350.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 37B (LRRC37B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321350.1

ORF Insert Sequence:

ATGTCAGCCC TGCCTCAGGA ACCAACTGAA AATTTGGCTC CATTCCTGAA GGAATTGGAT 
TCAGCTGGAG AGCTGCCCCT GGGGCCAGAG CCGTTCTTGG CTGCACATCA GGACTTAAAT 
GACAAGCGGA CTCCAGAAGA AAGGCTCCCA GAGGTGGTTC CGCTTCTCAA CCGGGATCAG 
AACCAGGCCC TAGTTCAGCT TCCTCGCCTC AAGTGGGTTC AAACTACAGA TCTAGATCGG 
GCTGCAGGTC ATCAGGCAGA TGAAATACTT GTTCCACTAG ACAGTAAGGT TTCAAGACCA 
ACCAAATTTG TTGTTTCGCC CAAGAACCTG AAGAAAGATC TAGCTGAACG TTGGAGCCTT 
CCTGAGATTG TTGGGATTCC ACACCAATTA TCCAAACCTC AGCGTCAGAA ACAGACTTTG 
CCAGATGATT ATTTGAGTAT GGACACACTG TATCCCGGCA GCCTACCTCC AGAACTCCGG 
GTGAACGCAG ATGAGCCTCC AGGGCCTCCT GAGCAAGTTG GACTTTCTCA ATTCCATCTA 
GAGCCCAAAA GTCAAAATCC AGAGACCCTT GAAGACATCC AGTCCTCTTC ACTCCAGGAA 
GAAGCCCCAG CGCAGCTTCT ACAGCTCCCT CAGGAGGTAG AACCTTCAAC CCAGCAGGAG 
GCCCCAGCTC TGCCTCCAGA GTCCTCTATG GAGAGTCTAG CTCAAACTCC ACTGAATCAT 
GAAGTGACAG TTCAACCTCC AGGTGAGGAT CAAGCTCATT ATAATTTGCC CAAGTTTACA 
GTCAAACCTG CAGATGTGGA GGTTACCATG ACTTCAGAGC CTAAAAATGA GACAGAATCT 
ACCCAAGCCC AGCAGGAGGC CCCAATTCAG CCTCCCGAGG AGGCGGAACC TTCTTCTACA 
GCCCTGAGGA CTACAGATCC TCCTCCAGAA CACCCTGAGG TGACACTTCC ACCTTCAGAC 
AAGGGTCAGG CTCAGCATTC ACACCTGACT GAAGCCACAG TTCAACCTCT GGACCTGGAG 
CTTAGCATAA CTACAGAGCC TACTACAGAG GTTAAACCGT CTCCAACCAC GGAGGAAACC 
TCAGCTCAGC CTCCAGACCC GGGGCTTGCC ATAACTCCAG AACCCACTAC AGAGATTGGA 
CATTCCACAG CCCTGGAGAA GACTAGAGCT CCTCATCCAG ACCAGGTTCA GACTCTGCAT 
CGAAGCCTGA CTGAAGTCAC AGGTCCACCT ACAAAGTTAG AATCTTCGCA GGATTCATTG 
GTGCAGTCTG AAACTGCACC AGAGGAACAG AAGGCCTCCA CAAGCACCAA CATATGTGAG 
CTCTGCACCT GCGGAGATGA GACTCTGTCA TGTGTTGGTC TCAGCCCAAA GCAGAGGCTC 
CGCCAAGTGC CTGTGCCAGA GCCCGACACC TACAATGGCA TCTTCACCAC CTTAAATTTC 
CAAGGAAACT ATATTTCATA CCTTGATGGA AATGTATGGA AAGCATACAG TTGGACCGAG 
AAACTAATTC TCAGTGAAAA TTATTTGACT GAATTACCTA AGGATTCATT TGAAGGCCTG 
CTATACCTCC AGTATTTAGA TTTATCCTGC AATAAAATAC GATATATTGA AAGACAAACA 
TTTGAATCAC TACCATTTTT GCAGTATATA AATCTGGGCT GCAATTTAAT TACAAAACTG 
AGCCTTGGAA CATTTCAGGC CTGGCACGGA ATGCAGTTTT TACACAACTT AATTCTCAAT 
CGCAATCCTC TGACTACTGT CGAAGATCCA TATCTCTTTG AACTGCCGGC ATTAAAATAT 
CTAGACATGG GAACAACACA CATCACACTT ACAACACTTA AGAACATTCT CACGATGACT 
GTTGAACTGG AAAAACTGAT CTTACCTAGC CATATGGCCT GCTGCCTCTG CCAATTTAAA 
AATAGCATTG AGGCTGTCTG CAAGACAGTC AAGCTGCATT GCAACACTGC ATGTCTGACT 
AACAGCATAC ATTGTCCTGA AGAAGCATCT GTAGGGAATC CAGAAGGAGC GTTCATGAAG 
ATGTTACAAG CCCGGAAGCA GCACATGAGC ACTCAGCTGA CTATTGAGTC GGAGGCGCCC 
TCAGACAGCA GTGGCATCAA CTTGTCAGGC TTTGGGGGTG ATCAGCTTGA AATTCAGCTA 
ACCGAGCAGC TACGGTCCCT CATCCCCAAC GAGGATGTGA GAAAGTTCAT GTCTCATGTT 
ATCCGGACCT TGAAAATGGA ATGTTCAGAA ACACATGTGC AAGGGAGCTG TGCCAAGCTC 
ATGTTGCGAA CAGGCCTCCT GATGAAGCTT CTCAGCGAGC AGCAGGAAGC AAAGGCATTG 
AATGTAGAAT GGGATACGGA CCAACAAAAA ACAAATTATA TTAATGAGAA CATGGAACAG 
AATGAACAGA AAGAGCAGAA GTCAAGTGAG CTCATGAAAG AAGTTCCAGG AGATGACTAT 
AAGAACAAAC TCATCTTCGC AATATCTGTG ACTGTAATAC TAATAATTTT GATTATAATT 
TTTTGTCTTA TAGAGGTGAA TTCACATAAA AGGGCATCAG AAAAATACAA AGACAACCCA 
TCAATATCAG GAGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC37B ( NM_052888.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_443120.2 Homo sapiens leucine rich repeat containing 37B (LRRC37B), transcript variant 1, mRNA.

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CloneID	OHu05552
Clone ID Related Accession (Same CDS sequence)	NM_052888.2 , NM_052888.3
Accession Version	NM_052888.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2844bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-13
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 37B isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC090616.13 and AK302740.1. On Aug 14, 2019 this sequence version replaced NM_052888.2. Transcript Variant: This variant (1) represents the shorter transcript and encodes the longer isoform (1), which contains a predicted signal peptide. ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCTTGGC TGCGTTTCTG GGGCCCATGG CCCCTCCTTA CGTGGCAACT ATTGTCTTTA 
CTAGTCAAGG AGGCTCAGCC TCTGGTGTGG GTCAAGGACC CGCTCCAGCT GACCTCTAAC 
CCCCTGGGGC CACCTGAGCC CTGGTCTTCC CGCTCCTCCC ATCTCCCATG GGAATCTCCC 
CATGCACCTG CTCCCCCAGC AGCCCCGGGG GACTTTGATT ACCTGGGGCC CTCTGCTTCT 
TCGCAGATGT CAGCCCTGCC TCAGGAACCA ACTGAAAATT TGGCTCCATT CCTGAAGGAA 
TTGGATTCAG CTGGAGAGCT GCCCCTGGGG CCAGAGCCGT TCTTGGCTGC ACATCAGGAC 
TTAAATGACA AGCGGACTCC AGAAGAAAGG CTCCCAGAGG TGGTTCCGCT TCTCAACCGG 
GATCAGAACC AGGCCCTAGT TCAGCTTCCT CGCCTCAAGT GGGTTCAAAC TACAGATCTA 
GATCGGGCTG CAGGTCATCA GGCAGATGAA ATACTTGTTC CACTAGACAG TAAGGTTTCA 
AGACCAACCA AATTTGTTGT TTCGCCCAAG AACCTGAAGA AAGATCTAGC TGAACGTTGG 
AGCCTTCCTG AGATTGTTGG GATTCCACAC CAATTATCCA AACCTCAGCG TCAGAAACAG 
ACTTTGCCAG ATGATTATTT GAGTATGGAC ACACTGTATC CCGGCAGCCT ACCTCCAGAA 
CTCCGGGTGA ACGCAGATGA GCCTCCAGGG CCTCCTGAGC AAGTTGGACT TTCTCAATTC 
CATCTAGAGC CCAAAAGTCA AAATCCAGAG ACCCTTGAAG ACATCCAGTC CTCTTCACTC 
CAGGAAGAAG CCCCAGCGCA GCTTCTACAG CTCCCTCAGG AGGTAGAACC TTCAACCCAG 
CAGGAGGCCC CAGCTCTGCC TCCAGAGTCC TCTATGGAGA GTCTAGCTCA AACTCCACTG 
AATCATGAAG TGACAGTTCA ACCTCCAGGT GAGGATCAAG CTCATTATAA TTTGCCCAAG 
TTTACAGTCA AACCTGCAGA TGTGGAGGTT ACCATGACTT CAGAGCCTAA AAATGAGACA 
GAATCTACCC AAGCCCAGCA GGAGGCCCCA ATTCAGCCTC CCGAGGAGGC GGAACCTTCT 
TCTACAGCCC TGAGGACTAC AGATCCTCCT CCAGAACACC CTGAGGTGAC ACTTCCACCT 
TCAGACAAGG GTCAGGCTCA GCATTCACAC CTGACTGAAG CCACAGTTCA ACCTCTGGAC 
CTGGAGCTTA GCATAACTAC AGAGCCTACT ACAGAGGTTA AACCGTCTCC AACCACGGAG 
GAAACCTCAG CTCAGCCTCC AGACCCGGGG CTTGCCATAA CTCCAGAACC CACTACAGAG 
ATTGGACATT CCACAGCCCT GGAGAAGACT AGAGCTCCTC ATCCAGACCA GGTTCAGACT 
CTGCATCGAA GCCTGACTGA AGTCACAGGT CCACCTACAA AGTTAGAATC TTCGCAGGAT 
TCATTGGTGC AGTCTGAAAC TGCACCAGAG GAACAGAAGG CCTCCACAAG CACCAACATA 
TGTGAGCTCT GCACCTGCGG AGATGAGACT CTGTCATGTG TTGGTCTCAG CCCAAAGCAG 
AGGCTCCGCC AAGTGCCTGT GCCAGAGCCC GACACCTACA ATGGCATCTT CACCACCTTA 
AATTTCCAAG GAAACTATAT TTCATACCTT GATGGAAATG TATGGAAAGC ATACAGTTGG 
ACCGAGAAAC TAATTCTCAG TGAAAATTAT TTGACTGAAT TACCTAAGGA TTCATTTGAA 
GGCCTGCTAT ACCTCCAGTA TTTAGATTTA TCCTGCAATA AAATACGATA TATTGAAAGA 
CAAACATTTG AATCACTACC ATTTTTGCAG TATATAAATC TGGGCTGCAA TTTAATTACA 
AAACTGAGCC TTGGAACATT TCAGGCCTGG CACGGAATGC AGTTTTTACA CAACTTAATT 
CTCAATCGCA ATCCTCTGAC TACTGTCGAA GATCCATATC TCTTTGAACT GCCGGCATTA 
AAATATCTAG ACATGGGAAC AACACACATC ACACTTACAA CACTTAAGAA CATTCTCACG 
ATGACTGTTG AACTGGAAAA ACTGATCTTA CCTAGCCATA TGGCCTGCTG CCTCTGCCAA 
TTTAAAAATA GCATTGAGGC TGTCTGCAAG ACAGTCAAGC TGCATTGCAA CACTGCATGT 
CTGACTAACA GCATACATTG TCCTGAAGAA GCATCTGTAG GGAATCCAGA AGGAGCGTTC 
ATGAAGATGT TACAAGCCCG GAAGCAGCAC ATGAGCACTC AGCTGACTAT TGAGTCGGAG 
GCGCCCTCAG ACAGCAGTGG CATCAACTTG TCAGGCTTTG GGGGTGATCA GCTTGAAATT 
CAGCTAACCG AGCAGCTACG GTCCCTCATC CCCAACGAGG ATGTGAGAAA GTTCATGTCT 
CATGTTATCC GGACCTTGAA AATGGAATGT TCAGAAACAC ATGTGCAAGG GAGCTGTGCC 
AAGCTCATGT TGCGAACAGG CCTCCTGATG AAGCTTCTCA GCGAGCAGCA GGAAGCAAAG 
GCATTGAATG TAGAATGGGA TACGGACCAA CAAAAAACAA ATTATATTAA TGAGAACATG 
GAACAGAATG AACAGAAAGA GCAGAAGTCA AGTGAGCTCA TGAAAGAAGT TCCAGGAGAT 
GACTATAAGA ACAAACTCAT CTTCGCAATA TCTGTGACTG TAATACTAAT AATTTTGATT 
ATAATTTTTT GTCTTATAGA GGTGAATTCA CATAAAAGGG CATCAGAAAA ATACAAAGAC 
AACCCATCAA TATCAGGAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_443120.2
CDS	40..2883
Translation	MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSSRSSHLPWESPHAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKELDSAGELPLGPEPFLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSKVSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQQEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTSTNICELCTCGDETLSCVGLSPKQRLRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILTMTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNTACLTNSIHCPEEASVGNPEGAFMKMLQARKQHMSTQLTIESEAPSDSSGINLSGFGGDQLEIQLTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCAKLMLRTGLLMKLLSEQQEAKALNVEWDTDQQKTNYINENMEQNEQKEQKSSELMKEVPGDDYKNKLIFAISVTVILIILIIIFCLIEVNSHKRASEKYKDNPSISGA

Target ORF information:

RefSeq Version	NM_052888.3
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 37B (LRRC37B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_052888.3

ORF Insert Sequence:

ATGTCTTGGC TGCGTTTCTG GGGCCCATGG CCCCTCCTTA CGTGGCAACT ATTGTCTTTA 
CTAGTCAAGG AGGCTCAGCC TCTGGTGTGG GTCAAGGACC CGCTCCAGCT GACCTCTAAC 
CCCCTGGGGC CACCTGAGCC CTGGTCTTCC CGCTCCTCCC ATCTCCCATG GGAATCTCCC 
CATGCACCTG CTCCCCCAGC AGCCCCGGGG GACTTTGATT ACCTGGGGCC CTCTGCTTCT 
TCGCAGATGT CAGCCCTGCC TCAGGAACCA ACTGAAAATT TGGCTCCATT CCTGAAGGAA 
TTGGATTCAG CTGGAGAGCT GCCCCTGGGG CCAGAGCCGT TCTTGGCTGC ACATCAGGAC 
TTAAATGACA AGCGGACTCC AGAAGAAAGG CTCCCAGAGG TGGTTCCGCT TCTCAACCGG 
GATCAGAACC AGGCCCTAGT TCAGCTTCCT CGCCTCAAGT GGGTTCAAAC TACAGATCTA 
GATCGGGCTG CAGGTCATCA GGCAGATGAA ATACTTGTTC CACTAGACAG TAAGGTTTCA 
AGACCAACCA AATTTGTTGT TTCGCCCAAG AACCTGAAGA AAGATCTAGC TGAACGTTGG 
AGCCTTCCTG AGATTGTTGG GATTCCACAC CAATTATCCA AACCTCAGCG TCAGAAACAG 
ACTTTGCCAG ATGATTATTT GAGTATGGAC ACACTGTATC CCGGCAGCCT ACCTCCAGAA 
CTCCGGGTGA ACGCAGATGA GCCTCCAGGG CCTCCTGAGC AAGTTGGACT TTCTCAATTC 
CATCTAGAGC CCAAAAGTCA AAATCCAGAG ACCCTTGAAG ACATCCAGTC CTCTTCACTC 
CAGGAAGAAG CCCCAGCGCA GCTTCTACAG CTCCCTCAGG AGGTAGAACC TTCAACCCAG 
CAGGAGGCCC CAGCTCTGCC TCCAGAGTCC TCTATGGAGA GTCTAGCTCA AACTCCACTG 
AATCATGAAG TGACAGTTCA ACCTCCAGGT GAGGATCAAG CTCATTATAA TTTGCCCAAG 
TTTACAGTCA AACCTGCAGA TGTGGAGGTT ACCATGACTT CAGAGCCTAA AAATGAGACA 
GAATCTACCC AAGCCCAGCA GGAGGCCCCA ATTCAGCCTC CCGAGGAGGC GGAACCTTCT 
TCTACAGCCC TGAGGACTAC AGATCCTCCT CCAGAACACC CTGAGGTGAC ACTTCCACCT 
TCAGACAAGG GTCAGGCTCA GCATTCACAC CTGACTGAAG CCACAGTTCA ACCTCTGGAC 
CTGGAGCTTA GCATAACTAC AGAGCCTACT ACAGAGGTTA AACCGTCTCC AACCACGGAG 
GAAACCTCAG CTCAGCCTCC AGACCCGGGG CTTGCCATAA CTCCAGAACC CACTACAGAG 
ATTGGACATT CCACAGCCCT GGAGAAGACT AGAGCTCCTC ATCCAGACCA GGTTCAGACT 
CTGCATCGAA GCCTGACTGA AGTCACAGGT CCACCTACAA AGTTAGAATC TTCGCAGGAT 
TCATTGGTGC AGTCTGAAAC TGCACCAGAG GAACAGAAGG CCTCCACAAG CACCAACATA 
TGTGAGCTCT GCACCTGCGG AGATGAGACT CTGTCATGTG TTGGTCTCAG CCCAAAGCAG 
AGGCTCCGCC AAGTGCCTGT GCCAGAGCCC GACACCTACA ATGGCATCTT CACCACCTTA 
AATTTCCAAG GAAACTATAT TTCATACCTT GATGGAAATG TATGGAAAGC ATACAGTTGG 
ACCGAGAAAC TAATTCTCAG TGAAAATTAT TTGACTGAAT TACCTAAGGA TTCATTTGAA 
GGCCTGCTAT ACCTCCAGTA TTTAGATTTA TCCTGCAATA AAATACGATA TATTGAAAGA 
CAAACATTTG AATCACTACC ATTTTTGCAG TATATAAATC TGGGCTGCAA TTTAATTACA 
AAACTGAGCC TTGGAACATT TCAGGCCTGG CACGGAATGC AGTTTTTACA CAACTTAATT 
CTCAATCGCA ATCCTCTGAC TACTGTCGAA GATCCATATC TCTTTGAACT GCCGGCATTA 
AAATATCTAG ACATGGGAAC AACACACATC ACACTTACAA CACTTAAGAA CATTCTCACG 
ATGACTGTTG AACTGGAAAA ACTGATCTTA CCTAGCCATA TGGCCTGCTG CCTCTGCCAA 
TTTAAAAATA GCATTGAGGC TGTCTGCAAG ACAGTCAAGC TGCATTGCAA CACTGCATGT 
CTGACTAACA GCATACATTG TCCTGAAGAA GCATCTGTAG GGAATCCAGA AGGAGCGTTC 
ATGAAGATGT TACAAGCCCG GAAGCAGCAC ATGAGCACTC AGCTGACTAT TGAGTCGGAG 
GCGCCCTCAG ACAGCAGTGG CATCAACTTG TCAGGCTTTG GGGGTGATCA GCTTGAAATT 
CAGCTAACCG AGCAGCTACG GTCCCTCATC CCCAACGAGG ATGTGAGAAA GTTCATGTCT 
CATGTTATCC GGACCTTGAA AATGGAATGT TCAGAAACAC ATGTGCAAGG GAGCTGTGCC 
AAGCTCATGT TGCGAACAGG CCTCCTGATG AAGCTTCTCA GCGAGCAGCA GGAAGCAAAG 
GCATTGAATG TAGAATGGGA TACGGACCAA CAAAAAACAA ATTATATTAA TGAGAACATG 
GAACAGAATG AACAGAAAGA GCAGAAGTCA AGTGAGCTCA TGAAAGAAGT TCCAGGAGAT 
GACTATAAGA ACAAACTCAT CTTCGCAATA TCTGTGACTG TAATACTAAT AATTTTGATT 
ATAATTTTTT GTCTTATAGA GGTGAATTCA CATAAAAGGG CATCAGAAAA ATACAAAGAC 
AACCCATCAA TATCAGGAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolutionary dynamism of the primate LRRC37 gene family.
Genome research23(1)46-59(2013 Jan)
Giannuzzi G,Siswara P,Malig M,Marques-Bonet T,,Mullikin JC,Ventura M,Eichler EE

Hundreds of variants clustered in genomic loci and biological pathways affect human height.
Nature467(7317)832-8(2010 Oct)
Lango Allen H,Estrada K,Lettre G,Berndt SI,Weedon MN,Rivadeneira F,Willer CJ,Jackson AU,Vedantam S,Raychaudhuri S,Ferreira T,Wood AR,Weyant RJ,Segr? AV,Speliotes EK,Wheeler E,Soranzo N,Park JH,Yang J,Gudbjartsson D,Heard-Costa NL,Randall JC,Qi L,Vernon Smith A,M?gi R,Pastinen T,Liang L,Heid IM,Luan J,Thorleifsson G,Winkler TW,Goddard ME,Sin Lo K,Palmer C,Workalemahu T,Aulchenko YS,Johansson A,Zillikens MC,Feitosa MF,Esko T,Johnson T,Ketkar S,Kraft P,Mangino M,Prokopenko I,Absher D,Albrecht E,Ernst F,Glazer NL,Hayward C,Hottenga JJ,Jacobs KB,Knowles JW,Kutalik Z,Monda KL,Polasek O,Preuss M,Rayner NW,Robertson NR,Steinthorsdottir V,Tyrer JP,Voight BF,Wiklund F,Xu J,Zhao JH,Nyholt DR,Pellikka N,Perola M,Perry JR,Surakka I,Tammesoo ML,Altmaier EL,Amin N,Aspelund T,Bhangale T,Boucher G,Chasman DI,Chen C,Coin L,Cooper MN,Dixon AL,Gibson Q,Grundberg E,Hao K,Juhani Junttila M,Kaplan LM,Kettunen J,K?nig IR,Kwan T,Lawrence RW,Levinson DF,Lorentzon M,McKnight B,Morris AP,M?ller M,Suh Ngwa J,Purcell S,Rafelt S,Salem RM,Salvi E,Sanna S,Shi J,Sovio U,Thompson JR,Turchin MC,Vandenput L,Verlaan DJ,Vitart V,White CC,Ziegler A,Almgren P,Balmforth AJ,Campbell H,Citterio L,De Grandi A,Dominiczak A,Duan J,Elliott P,Elosua R,Eriksson JG,Freimer NB,Geus EJ,Glorioso N,Haiqing S,Hartikainen AL,Havulinna AS,Hicks AA,Hui J,Igl W,Illig T,Jula A,Kajantie E,Kilpel?inen TO,Koiranen M,Kolcic I,Koskinen S,Kovacs P,Laitinen J,Liu J,Lokki ML,Marusic A,Maschio A,Meitinger T,Mulas A,Par? G,Parker AN,Peden JF,Petersmann A,Pichler I,Pietil?inen KH,Pouta A,Ridderstr?le M,Rotter JI,Sambrook JG,Sanders AR,Schmidt CO,Sinisalo J,Smit JH,Stringham HM,Bragi Walters G,Widen E,Wild SH,Willemsen G,Zagato L,Zgaga L,Zitting P,Alavere H,Farrall M,McArdle WL,Nelis M,Peters MJ,Ripatti S,van Meurs JB,Aben KK,Ardlie KG,Beckmann JS,Beilby JP,Bergman RN,Bergmann S,Collins FS,Cusi D,den Heijer M,Eiriksdottir G,Gejman PV,Hall AS,Hamsten A,Huikuri HV,Iribarren C,K?h?nen M,Kaprio J,Kathiresan S,Kiemeney L,Kocher T,Launer LJ,Lehtim?ki T,Melander O,Mosley TH Jr,Musk AW,Nieminen MS,O'Donnell CJ,Ohlsson C,Oostra B,Palmer LJ,Raitakari O,Ridker PM,Rioux JD,Rissanen A,Rivolta C,Schunkert H,Shuldiner AR,Siscovick DS,Stumvoll M,T?njes A,Tuomilehto J,van Ommen GJ,Viikari J,Heath AC,Martin NG,Montgomery GW,Province MA,Kayser M,Arnold AM,Atwood LD,Boerwinkle E,Chanock SJ,Deloukas P,Gieger C,Gr?nberg H,Hall P,Hattersley AT,Hengstenberg C,Hoffman W,Lathrop GM,Salomaa V,Schreiber S,Uda M,Waterworth D,Wright AF,Assimes TL,Barroso I,Hofman A,Mohlke KL,Boomsma DI,Caulfield MJ,Cupples LA,Erdmann J,Fox CS,Gudnason V,Gyllensten U,Harris TB,Hayes RB,Jarvelin MR,Mooser V,Munroe PB,Ouwehand WH,Penninx BW,Pramstaller PP,Quertermous T,Rudan I,Samani NJ,Spector TD,V?lzke H,Watkins H,Wilson JF,Groop LC,Haritunians T,Hu FB,Kaplan RC,Metspalu A,North KE,Schlessinger D,Wareham NJ,Hunter DJ,O'Connell JR,Strachan DP,Wichmann HE,Borecki IB,van Duijn CM,Schadt EE,Thorsteinsdottir U,Peltonen L,Uitterlinden AG,Visscher PM,Chatterjee N,Loos RJ,Boehnke M,McCarthy MI,Ingelsson E,Lindgren CM,Abecasis GR,Stefansson K,Frayling TM,Hirschhorn JN

RNF135 mutations are not present in patients with Sotos syndrome-like features.
American journal of medical genetics. Part A149A(4)806-8(2009 Feb)
Visser R,Koelma N,Vijfhuizen L,van der Wielen MJ,Kant SG,Breuning MH,Wit JM,Losekoot M

Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth.
Nature genetics39(8)963-5(2007 Aug)
Douglas J,Cilliers D,Coleman K,Tatton-Brown K,Barker K,Bernhard B,Burn J,Huson S,Josifova D,Lacombe D,Malik M,Mansour S,Reid E,Cormier-Daire V,Cole T,,Rahman N

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
Nature440(7087)1045-9(2006 Apr)
Zody MC,Garber M,Adams DJ,Sharpe T,Harrow J,Lupski JR,Nicholson C,Searle SM,Wilming L,Young SK,Abouelleil A,Allen NR,Bi W,Bloom T,Borowsky ML,Bugalter BE,Butler J,Chang JL,Chen CK,Cook A,Corum B,Cuomo CA,de Jong PJ,DeCaprio D,Dewar K,FitzGerald M,Gilbert J,Gibson R,Gnerre S,Goldstein S,Grafham DV,Grocock R,Hafez N,Hagopian DS,Hart E,Norman CH,Humphray S,Jaffe DB,Jones M,Kamal M,Khodiyar VK,LaButti K,Laird G,Lehoczky J,Liu X,Lokyitsang T,Loveland J,Lui A,Macdonald P,Major JE,Matthews L,Mauceli E,McCarroll SA,Mihalev AH,Mudge J,Nguyen C,Nicol R,O'Leary SB,Osoegawa K,Schwartz DC,Shaw-Smith C,Stankiewicz P,Steward C,Swarbreck D,Venkataraman V,Whittaker CA,Yang X,Zimmer AR,Bradley A,Hubbard T,Birren BW,Rogers J,Lander ES,Nusbaum C

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LRRC37B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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