STRAP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	STRAP
Entrez Gene ID	11171
Full Name	serine/threonine kinase receptor associated protein
Synonyms	MAWD,PT-WD,UNRIP
General protein information	Preferred Names serine/threonine kinase receptor associated protein Names serine-threonine kinase receptor-associated protein MAP activator with WD repeats WD-40 repeat protein PT-WD unr-interacting protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12p12.3
Disorder MIM:	605986

mRNA and Protein(s)

mRNA	Protein	Name
XM_005253294.2	XP_005253351.1	serine-threonine kinase receptor-associated protein isoform X1
NM_007178.3	NP_009109.3	serine-threonine kinase receptor-associated protein
NM_007178.4	NP_009109.3	serine-threonine kinase receptor-associated protein
XM_005253294.1	XP_005253351.1	serine-threonine kinase receptor-associated protein isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	STRAP	XP_543790.1
Mus musculus (house mouse)	Strap	NP_035629.2
Danio rerio (zebrafish)	strap	NP_956598.1
Pan troglodytes (chimpanzee)	STRAP	XP_001159216.2
Rattus norvegicus (Norway rat)	Strap	NP_001011969.1
Xenopus tropicalis (tropical clawed frog)	strap	NP_001120495.1
Homo sapiens (human)	STRAP	NP_009109.3
Bos taurus (cattle)	STRAP	NP_001015567.1
Drosophila melanogaster (fruit fly)	wmd	NP_611804.1
Arabidopsis thaliana (thale cress)	AT1G15470	NP_563978.1
Gallus gallus (chicken)	STRAP	NP_001006247.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005029	XP_001688468.1

Gene Ontology
Bibliography

Related articles in PubMed

Downregulation of STRAP promotes tumor growth and metastasis in hepatocellular carcinoma via reducing PTEN level.
Wu Q, Yu S, Chen J, Li Y, Gao Y
IUBMB life(2017 Dec)

STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway.
Jin L, Vu T, Yuan G, Datta PK
Cancer research77(20)5464-5478(2017 Oct)

Novel role of STRAP in progression and metastasis of colorectal cancer through Wnt/?-catenin signaling.
Yuan G, Zhang B, Yang S, Jin L, Datta A, Bae S, Chen X, Datta PK
Oncotarget7(13)16023-37(2016 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Findings illuminated a novel STRAP-NOTCH1-HES1 molecular axis as a CSC regulator in colorectal cancer.
Title: STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway.

these results suggest that STRAP increases invasion and metastasis of colorectal cancer partly through inhibiting ubiquitin-dependent degradation of beta-catenin and promoting Wnt/beta-catenin signaling
Title: Novel role of STRAP in progression and metastasis of colorectal cancer through Wnt/?-catenin signaling.

MAWD and MAWBP were downregulated and associated with the differentiation grade in GC tissues.
Title: Mitogen-activated protein kinase activator with WD40 repeats (MAWD) and MAWD-binding protein induce cell differentiation in gastric cancer.

Strap augments the apoptotic effects of mitochondrial p53.
Title: Cofactor Strap regulates oxidative phosphorylation and mitochondrial p53 activity through ATP synthase.

STRAP inhibits the transactivation function of Sp1 either by directly blocking its DNA binding domain or destabilizing Sp1 protein through ubiquitin-proteasome pathway in cell cycle G1 phase.
Title: Oncogenic STRAP functions as a novel negative regulator of E-cadherin and p21(Cip1) by modulating the transcription factor Sp1.

The following STRAP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the STRAP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16654	NM_007178.4 Latest version!	Homo sapiens serine/threonine kinase receptor associated protein (STRAP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu46045	XM_005253294.2 Latest version!	Homo sapiens serine/threonine kinase receptor associated protein (STRAP), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
View Old Accession Versions >>
OHu16654	NM_007178.3	Homo sapiens serine/threonine kinase receptor associated protein (STRAP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu46045	XM_005253294.1	Homo sapiens serine/threonine kinase receptor associated protein (STRAP), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

STRAP ( NM_007178.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_009109.3 Homo sapiens serine/threonine kinase receptor associated protein (STRAP), mRNA.

Price & Availability↑

CloneID	OHu16654
Clone ID Related Accession (Same CDS sequence)	NM_007178.3 , NM_007178.4
Accession Version	NM_007178.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1053bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-10
Organism	Homo sapiens(human)
Product	serine-threonine kinase receptor-associated protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA666505.1 and BC062306.1. On Jun 8, 2007 this sequence version replaced NM_007178.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC062306.1, SRR1163655.182265.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGCAATGA GACAGACGCC GCTCACCTGC TCTGGCCACA CGCGACCCGT GGTTGATTTG 
GCCTTCAGTG GCATCACGCC TTATGGGTAT TTCTTAATCA GCGCTTGCAA AGATGGTAAA 
CCTATGCTAC GCCAGGGAGA TACAGGAGAC TGGATTGGAA CATTTTTGGG TCATAAAGGT 
GCTGTTTGGG GTGCAACACT GAATAAGGAT GCCACCAAAG CAGCTACAGC AGCTGCAGAT 
TTCACAGCCA AAGTGTGGGA TGCTGTCTCA GGAGATGAAT TGATGACCCT GGCTCATAAA 
CACATTGTCA AGACTGTGGA TTTCACGCAG GATAGTAATT ATTTGTTAAC CGGGGGACAG 
GATAAACTGT TACGCATATA TGACTTGAAC AAACCTGAAG CAGAACCTAA GGAAATTAGT 
GGTCATACTT CTGGTATAAA AAAAGCTCTG TGGTGCAGTG AGGATAAACA GATTCTTTCT 
GCTGATGACA AAACTGTTCG ACTTTGGGAT CATGCTACTA TGACAGAAGT GAAATCTCTA 
AATTTTAATA TGTCTGTTAG TAGTATGGAA TATATTCCTG AGGGAGAGAT TTTGGTTATA 
ACTTATGGAC GATCTATTGC TTTTCATAGT GCAGTAAGTT TGGACCCAAT TAAATCCTTT 
GAAGCTCCTG CAACCATCAA TTCTGCATCT CTTCATCCTG AGAAAGAATT TCTTGTTGCA 
GGCGGTGAAG ATTTTAAACT TTATAAGTAT GATTATAATA GTGGAGAAGA ATTAGAATCC 
TACAAGGGAC ACTTTGGTCC TATTCACTGT GTGAGATTTA GTCCTGATGG AGAACTCTAT 
GCCAGTGGTT CAGAAGATGG AACATTGAGA CTATGGCAAA CTGTGGTAGG AAAAACGTAT 
GGCCTTTGGA AATGTGTGCT TCCTGAAGAA GATAGTGGTG AGCTGGCAAA GCCAAAGATT 
GGTTTTCCAG AGACAACAGA AGAGGAGCTA GAAGAAATTG CTTCAGAGAA TTCAGATTGC 
ATCTTTCCTT CAGCTCCTGA TGTTAAGGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009109.3
CDS	355..1407
Translation	MAMRQTPLTCSGHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSADDKTVRLWDHATMTEVKSLNFNMSVSSMEYIPEGEILVITYGRSIAFHSAVSLDPIKSFEAPATINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWKCVLPEEDSGELAKPKIGFPETTEEELEEIASENSDCIFPSAPDVKA

Target ORF information:

RefSeq Version	NM_007178.3
Organism	Homo sapiens(human)
Definition	Homo sapiens serine/threonine kinase receptor associated protein (STRAP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007178.3

ORF Insert Sequence:

ATGGCAATGA GACAGACGCC GCTCACCTGC TCTGGCCACA CGCGACCCGT GGTTGATTTG 
GCCTTCAGTG GCATCACGCC TTATGGGTAT TTCTTAATCA GCGCTTGCAA AGATGGTAAA 
CCTATGCTAC GCCAGGGAGA TACAGGAGAC TGGATTGGAA CATTTTTGGG TCATAAAGGT 
GCTGTTTGGG GTGCAACACT GAATAAGGAT GCCACCAAAG CAGCTACAGC AGCTGCAGAT 
TTCACAGCCA AAGTGTGGGA TGCTGTCTCA GGAGATGAAT TGATGACCCT GGCTCATAAA 
CACATTGTCA AGACTGTGGA TTTCACGCAG GATAGTAATT ATTTGTTAAC CGGGGGACAG 
GATAAACTGT TACGCATATA TGACTTGAAC AAACCTGAAG CAGAACCTAA GGAAATTAGT 
GGTCATACTT CTGGTATAAA AAAAGCTCTG TGGTGCAGTG AGGATAAACA GATTCTTTCT 
GCTGATGACA AAACTGTTCG ACTTTGGGAT CATGCTACTA TGACAGAAGT GAAATCTCTA 
AATTTTAATA TGTCTGTTAG TAGTATGGAA TATATTCCTG AGGGAGAGAT TTTGGTTATA 
ACTTATGGAC GATCTATTGC TTTTCATAGT GCAGTAAGTT TGGACCCAAT TAAATCCTTT 
GAAGCTCCTG CAACCATCAA TTCTGCATCT CTTCATCCTG AGAAAGAATT TCTTGTTGCA 
GGCGGTGAAG ATTTTAAACT TTATAAGTAT GATTATAATA GTGGAGAAGA ATTAGAATCC 
TACAAGGGAC ACTTTGGTCC TATTCACTGT GTGAGATTTA GTCCTGATGG AGAACTCTAT 
GCCAGTGGTT CAGAAGATGG AACATTGAGA CTATGGCAAA CTGTGGTAGG AAAAACGTAT 
GGCCTTTGGA AATGTGTGCT TCCTGAAGAA GATAGTGGTG AGCTGGCAAA GCCAAAGATT 
GGTTTTCCAG AGACAACAGA AGAGGAGCTA GAAGAAATTG CTTCAGAGAA TTCAGATTGC 
ATCTTTCCTT CAGCTCCTGA TGTTAAGGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STRAP ( NM_007178.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_009109.3 Homo sapiens serine/threonine kinase receptor associated protein (STRAP), mRNA.

Price & Availability↑

CloneID	OHu16654
Clone ID Related Accession (Same CDS sequence)	NM_007178.3 , NM_007178.4
Accession Version	NM_007178.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1053bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-29
Organism	Homo sapiens(human)
Product	serine-threonine kinase receptor-associated protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC022073.13. On Nov 24, 2018 this sequence version replaced NM_007178.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.1099325.1, SRR3476690.102734.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000419869.7/ ENSP00000392270.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCAATGA GACAGACGCC GCTCACCTGC TCTGGCCACA CGCGACCCGT GGTTGATTTG 
GCCTTCAGTG GCATCACGCC TTATGGGTAT TTCTTAATCA GCGCTTGCAA AGATGGTAAA 
CCTATGCTAC GCCAGGGAGA TACAGGAGAC TGGATTGGAA CATTTTTGGG TCATAAAGGT 
GCTGTTTGGG GTGCAACACT GAATAAGGAT GCCACCAAAG CAGCTACAGC AGCTGCAGAT 
TTCACAGCCA AAGTGTGGGA TGCTGTCTCA GGAGATGAAT TGATGACCCT GGCTCATAAA 
CACATTGTCA AGACTGTGGA TTTCACGCAG GATAGTAATT ATTTGTTAAC CGGGGGACAG 
GATAAACTGT TACGCATATA TGACTTGAAC AAACCTGAAG CAGAACCTAA GGAAATTAGT 
GGTCATACTT CTGGTATAAA AAAAGCTCTG TGGTGCAGTG AGGATAAACA GATTCTTTCT 
GCTGATGACA AAACTGTTCG ACTTTGGGAT CATGCTACTA TGACAGAAGT GAAATCTCTA 
AATTTTAATA TGTCTGTTAG TAGTATGGAA TATATTCCTG AGGGAGAGAT TTTGGTTATA 
ACTTATGGAC GATCTATTGC TTTTCATAGT GCAGTAAGTT TGGACCCAAT TAAATCCTTT 
GAAGCTCCTG CAACCATCAA TTCTGCATCT CTTCATCCTG AGAAAGAATT TCTTGTTGCA 
GGCGGTGAAG ATTTTAAACT TTATAAGTAT GATTATAATA GTGGAGAAGA ATTAGAATCC 
TACAAGGGAC ACTTTGGTCC TATTCACTGT GTGAGATTTA GTCCTGATGG AGAACTCTAT 
GCCAGTGGTT CAGAAGATGG AACATTGAGA CTATGGCAAA CTGTGGTAGG AAAAACGTAT 
GGCCTTTGGA AATGTGTGCT TCCTGAAGAA GATAGTGGTG AGCTGGCAAA GCCAAAGATT 
GGTTTTCCAG AGACAACAGA AGAGGAGCTA GAAGAAATTG CTTCAGAGAA TTCAGATTGC 
ATCTTTCCTT CAGCTCCTGA TGTTAAGGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009109.3
CDS	322..1374
Translation	MAMRQTPLTCSGHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSADDKTVRLWDHATMTEVKSLNFNMSVSSMEYIPEGEILVITYGRSIAFHSAVSLDPIKSFEAPATINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWKCVLPEEDSGELAKPKIGFPETTEEELEEIASENSDCIFPSAPDVKA

Target ORF information:

RefSeq Version	NM_007178.4
Organism	Homo sapiens(human)
Definition	Homo sapiens serine/threonine kinase receptor associated protein (STRAP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007178.4

ORF Insert Sequence:

ATGGCAATGA GACAGACGCC GCTCACCTGC TCTGGCCACA CGCGACCCGT GGTTGATTTG 
GCCTTCAGTG GCATCACGCC TTATGGGTAT TTCTTAATCA GCGCTTGCAA AGATGGTAAA 
CCTATGCTAC GCCAGGGAGA TACAGGAGAC TGGATTGGAA CATTTTTGGG TCATAAAGGT 
GCTGTTTGGG GTGCAACACT GAATAAGGAT GCCACCAAAG CAGCTACAGC AGCTGCAGAT 
TTCACAGCCA AAGTGTGGGA TGCTGTCTCA GGAGATGAAT TGATGACCCT GGCTCATAAA 
CACATTGTCA AGACTGTGGA TTTCACGCAG GATAGTAATT ATTTGTTAAC CGGGGGACAG 
GATAAACTGT TACGCATATA TGACTTGAAC AAACCTGAAG CAGAACCTAA GGAAATTAGT 
GGTCATACTT CTGGTATAAA AAAAGCTCTG TGGTGCAGTG AGGATAAACA GATTCTTTCT 
GCTGATGACA AAACTGTTCG ACTTTGGGAT CATGCTACTA TGACAGAAGT GAAATCTCTA 
AATTTTAATA TGTCTGTTAG TAGTATGGAA TATATTCCTG AGGGAGAGAT TTTGGTTATA 
ACTTATGGAC GATCTATTGC TTTTCATAGT GCAGTAAGTT TGGACCCAAT TAAATCCTTT 
GAAGCTCCTG CAACCATCAA TTCTGCATCT CTTCATCCTG AGAAAGAATT TCTTGTTGCA 
GGCGGTGAAG ATTTTAAACT TTATAAGTAT GATTATAATA GTGGAGAAGA ATTAGAATCC 
TACAAGGGAC ACTTTGGTCC TATTCACTGT GTGAGATTTA GTCCTGATGG AGAACTCTAT 
GCCAGTGGTT CAGAAGATGG AACATTGAGA CTATGGCAAA CTGTGGTAGG AAAAACGTAT 
GGCCTTTGGA AATGTGTGCT TCCTGAAGAA GATAGTGGTG AGCTGGCAAA GCCAAAGATT 
GGTTTTCCAG AGACAACAGA AGAGGAGCTA GAAGAAATTG CTTCAGAGAA TTCAGATTGC 
ATCTTTCCTT CAGCTCCTGA TGTTAAGGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STRAP ( XM_005253294.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005253351.1 Homo sapiens serine/threonine kinase receptor associated protein (STRAP), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu46045
Clone ID Related Accession (Same CDS sequence)	XM_005253294.2 , XM_005253294.1
Accession Version	XM_005253294.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 771bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	serine-threonine kinase receptor-associated protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005253294.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCCTGG CTCATAAACA CATTGTCAAG ACTGTGGATT TCACGCAGGA TAGTAATTAT 
TTGTTAACCG GGGGACAGGA TAAACTGTTA CGCATATATG ACTTGAACAA ACCTGAAGCA 
GAACCTAAGG AAATTAGTGG TCATACTTCT GGTATAAAAA AAGCTCTGTG GTGCAGTGAG 
GATAAACAGA TTCTTTCTGC TGATGACAAA ACTGTTCGAC TTTGGGATCA TGCTACTATG 
ACAGAAGTGA AATCTCTAAA TTTTAATATG TCTGTTAGTA GTATGGAATA TATTCCTGAG 
GGAGAGATTT TGGTTATAAC TTATGGACGA TCTATTGCTT TTCATAGTGC AGTAAGTTTG 
GACCCAATTA AATCCTTTGA AGCTCCTGCA ACCATCAATT CTGCATCTCT TCATCCTGAG 
AAAGAATTTC TTGTTGCAGG CGGTGAAGAT TTTAAACTTT ATAAGTATGA TTATAATAGT 
GGAGAAGAAT TAGAATCCTA CAAGGGACAC TTTGGTCCTA TTCACTGTGT GAGATTTAGT 
CCTGATGGAG AACTCTATGC CAGTGGTTCA GAAGATGGAA CATTGAGACT ATGGCAAACT 
GTGGTAGGAA AAACGTATGG CCTTTGGAAA TGTGTGCTTC CTGAAGAAGA TAGTGGTGAG 
CTGGCAAAGC CAAAGATTGG TTTTCCAGAG ACAACAGAAG AGGAGCTAGA AGAAATTGCT 
TCAGAGAATT CAGATTGCAT CTTTCCTTCA GCTCCTGATG TTAAGGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005253351.1
CDS	473..1243
Translation	MTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSADDKTVRLWDHATMTEVKSLNFNMSVSSMEYIPEGEILVITYGRSIAFHSAVSLDPIKSFEAPATINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWKCVLPEEDSGELAKPKIGFPETTEEELEEIASENSDCIFPSAPDVKA

Target ORF information:

RefSeq Version	XM_005253294.2
Organism	Homo sapiens(human)
Definition	Homo sapiens serine/threonine kinase receptor associated protein (STRAP), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005253294.2

ORF Insert Sequence:

ATGACCCTGG CTCATAAACA CATTGTCAAG ACTGTGGATT TCACGCAGGA TAGTAATTAT 
TTGTTAACCG GGGGACAGGA TAAACTGTTA CGCATATATG ACTTGAACAA ACCTGAAGCA 
GAACCTAAGG AAATTAGTGG TCATACTTCT GGTATAAAAA AAGCTCTGTG GTGCAGTGAG 
GATAAACAGA TTCTTTCTGC TGATGACAAA ACTGTTCGAC TTTGGGATCA TGCTACTATG 
ACAGAAGTGA AATCTCTAAA TTTTAATATG TCTGTTAGTA GTATGGAATA TATTCCTGAG 
GGAGAGATTT TGGTTATAAC TTATGGACGA TCTATTGCTT TTCATAGTGC AGTAAGTTTG 
GACCCAATTA AATCCTTTGA AGCTCCTGCA ACCATCAATT CTGCATCTCT TCATCCTGAG 
AAAGAATTTC TTGTTGCAGG CGGTGAAGAT TTTAAACTTT ATAAGTATGA TTATAATAGT 
GGAGAAGAAT TAGAATCCTA CAAGGGACAC TTTGGTCCTA TTCACTGTGT GAGATTTAGT 
CCTGATGGAG AACTCTATGC CAGTGGTTCA GAAGATGGAA CATTGAGACT ATGGCAAACT 
GTGGTAGGAA AAACGTATGG CCTTTGGAAA TGTGTGCTTC CTGAAGAAGA TAGTGGTGAG 
CTGGCAAAGC CAAAGATTGG TTTTCCAGAG ACAACAGAAG AGGAGCTAGA AGAAATTGCT 
TCAGAGAATT CAGATTGCAT CTTTCCTTCA GCTCCTGATG TTAAGGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STRAP ( XM_005253294.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005253351.1 Homo sapiens serine/threonine kinase receptor associated protein (STRAP), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu46045
Clone ID Related Accession (Same CDS sequence)	XM_005253294.2 , XM_005253294.1
Accession Version	XM_005253294.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 771bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	serine-threonine kinase receptor-associated protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCCTGG CTCATAAACA CATTGTCAAG ACTGTGGATT TCACGCAGGA TAGTAATTAT 
TTGTTAACCG GGGGACAGGA TAAACTGTTA CGCATATATG ACTTGAACAA ACCTGAAGCA 
GAACCTAAGG AAATTAGTGG TCATACTTCT GGTATAAAAA AAGCTCTGTG GTGCAGTGAG 
GATAAACAGA TTCTTTCTGC TGATGACAAA ACTGTTCGAC TTTGGGATCA TGCTACTATG 
ACAGAAGTGA AATCTCTAAA TTTTAATATG TCTGTTAGTA GTATGGAATA TATTCCTGAG 
GGAGAGATTT TGGTTATAAC TTATGGACGA TCTATTGCTT TTCATAGTGC AGTAAGTTTG 
GACCCAATTA AATCCTTTGA AGCTCCTGCA ACCATCAATT CTGCATCTCT TCATCCTGAG 
AAAGAATTTC TTGTTGCAGG CGGTGAAGAT TTTAAACTTT ATAAGTATGA TTATAATAGT 
GGAGAAGAAT TAGAATCCTA CAAGGGACAC TTTGGTCCTA TTCACTGTGT GAGATTTAGT 
CCTGATGGAG AACTCTATGC CAGTGGTTCA GAAGATGGAA CATTGAGACT ATGGCAAACT 
GTGGTAGGAA AAACGTATGG CCTTTGGAAA TGTGTGCTTC CTGAAGAAGA TAGTGGTGAG 
CTGGCAAAGC CAAAGATTGG TTTTCCAGAG ACAACAGAAG AGGAGCTAGA AGAAATTGCT 
TCAGAGAATT CAGATTGCAT CTTTCCTTCA GCTCCTGATG TTAAGGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005253351.1
CDS	499..1269
Translation	MTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSADDKTVRLWDHATMTEVKSLNFNMSVSSMEYIPEGEILVITYGRSIAFHSAVSLDPIKSFEAPATINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWKCVLPEEDSGELAKPKIGFPETTEEELEEIASENSDCIFPSAPDVKA

Target ORF information:

RefSeq Version	XM_005253294.1
Organism	Homo sapiens(human)
Definition	Homo sapiens serine/threonine kinase receptor associated protein (STRAP), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005253294.1

ORF Insert Sequence:

ATGACCCTGG CTCATAAACA CATTGTCAAG ACTGTGGATT TCACGCAGGA TAGTAATTAT 
TTGTTAACCG GGGGACAGGA TAAACTGTTA CGCATATATG ACTTGAACAA ACCTGAAGCA 
GAACCTAAGG AAATTAGTGG TCATACTTCT GGTATAAAAA AAGCTCTGTG GTGCAGTGAG 
GATAAACAGA TTCTTTCTGC TGATGACAAA ACTGTTCGAC TTTGGGATCA TGCTACTATG 
ACAGAAGTGA AATCTCTAAA TTTTAATATG TCTGTTAGTA GTATGGAATA TATTCCTGAG 
GGAGAGATTT TGGTTATAAC TTATGGACGA TCTATTGCTT TTCATAGTGC AGTAAGTTTG 
GACCCAATTA AATCCTTTGA AGCTCCTGCA ACCATCAATT CTGCATCTCT TCATCCTGAG 
AAAGAATTTC TTGTTGCAGG CGGTGAAGAT TTTAAACTTT ATAAGTATGA TTATAATAGT 
GGAGAAGAAT TAGAATCCTA CAAGGGACAC TTTGGTCCTA TTCACTGTGT GAGATTTAGT 
CCTGATGGAG AACTCTATGC CAGTGGTTCA GAAGATGGAA CATTGAGACT ATGGCAAACT 
GTGGTAGGAA AAACGTATGG CCTTTGGAAA TGTGTGCTTC CTGAAGAAGA TAGTGGTGAG 
CTGGCAAAGC CAAAGATTGG TTTTCCAGAG ACAACAGAAG AGGAGCTAGA AGAAATTGCT 
TCAGAGAATT CAGATTGCAT CTTTCCTTCA GCTCCTGATG TTAAGGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Downregulation of STRAP promotes tumor growth and metastasis in hepatocellular carcinoma via reducing PTEN level.
IUBMB life(2017 Dec)
Wu Q,Yu S,Chen J,Li Y,Gao Y

STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway.
Cancer research77(20)5464-5478(2017 Oct)
Jin L,Vu T,Yuan G,Datta PK

Novel role of STRAP in progression and metastasis of colorectal cancer through Wnt/?-catenin signaling.
Oncotarget7(13)16023-37(2016 Mar)
Yuan G,Zhang B,Yang S,Jin L,Datta A,Bae S,Chen X,Datta PK