ADAMTS5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ADAMTS5
Entrez Gene ID	11096
Full Name	ADAM metallopeptidase with thrombospondin type 1 motif 5
Synonyms	ADAM-TS 11,ADAM-TS 5,ADAM-TS5,ADAMTS-11,ADAMTS-5,ADAMTS11,ADMP-2
General protein information	Preferred Names ADAM metallopeptidase with thrombospondin type 1 motif 5 Names A disintegrin and metalloproteinase with thrombospondin motifs 5 a disintegrin and metalloproteinase with thrombospondin motifs 11 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) aggrecanase-2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 21 Map Location: 21q21.3
Summary	This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016].
Disorder MIM:	605007

mRNA and Protein(s)

mRNA	Protein	Name
NM_007038.4	NP_008969.2	A disintegrin and metalloproteinase with thrombospondin motifs 5 preproprotein
NM_007038.5	NP_008969.2	A disintegrin and metalloproteinase with thrombospondin motifs 5 preproprotein
XM_011529448.2	XP_011527750.1	A disintegrin and metalloproteinase with thrombospondin motifs 5 isoform X1
XM_024452053.1	XP_024307821.1	A disintegrin and metalloproteinase with thrombospondin motifs 5 isoform X1
XM_024452054.1	XP_024307822.1	A disintegrin and metalloproteinase with thrombospondin motifs 5 isoform X2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Adamts5	NP_035912.2
Canis lupus familiaris (dog)	ADAMTS5	XP_851118.2
Bos taurus (cattle)	ADAMTS5	NP_001159987.1
Gallus gallus (chicken)	ADAMTS5	XP_425541.4
Xenopus tropicalis (tropical clawed frog)	adamts5	XP_002935740.1
Pan troglodytes (chimpanzee)	ADAMTS5	XP_531407.2
Danio rerio (zebrafish)	adamts5	XP_693454.6
Homo sapiens (human)	ADAMTS5	NP_008969.2
	ADAMTS5	XP_001103439.1
Rattus norvegicus (Norway rat)	Adamts5	NP_942056.1

Gene Ontology

The following ADAMTS5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ADAMTS5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27335	NM_007038.5 Latest version!	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu27335	XM_024452053.1 Latest version!	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu64714	XM_011529448.2 Latest version!	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu64714	XM_024452054.1 Latest version!	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
View Old Accession Versions >>
OHu27335	NM_007038.4	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ADAMTS5 ( NM_007038.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_008969.2 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5), mRNA.

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CloneID	OHu27335
Clone ID Related Accession (Same CDS sequence)	NM_007038.4 , NM_007038.5 , XM_024452053.1
Accession Version	NM_007038.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2793bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-02
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 5 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK094057.1, AP001601.1, AF142099.1, AP001600.1 and CA313018.1. On Feb 27, 2016 this sequence version replaced NM_007038.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF142099.1, SRR1660807.260679.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGCTCG GGTGGGCGTC CCTGCTGCTG TGCGCGTTCC GCCTGCCCCT GGCCGCGGTC 
GGCCCCGCCG CGACACCTGC CCAGGATAAA GCCGGGCAGC CTCCGACTGC TGCAGCAGCC 
GCCCAGCCCC GCCGGCGGCA GGGGGAGGAG GTGCAGGAGC GAGCCGAGCC TCCCGGCCAC 
CCGCACCCCC TGGCGCAGCG GCGCAGGAGC AAGGGGCTGG TGCAGAACAT CGACCAACTC 
TACTCCGGCG GCGGCAAGGT GGGCTACCTC GTCTACGCGG GCGGCCGGAG GTTCCTCTTG 
GACCTGGAGC GAGATGGTTC GGTGGGCATT GCTGGCTTCG TGCCCGCAGG AGGCGGGACG 
AGTGCGCCCT GGCGCCACCG GAGCCACTGC TTCTATCGGG GCACAGTGGA CGGTAGTCCC 
CGCTCTCTGG CTGTCTTTGA CCTCTGTGGG GGTCTCGACG GCTTCTTCGC GGTCAAGCAC 
GCGCGCTACA CCCTAAAGCC ACTGCTGCGC GGACCCTGGG CGGAGGAAGA AAAGGGGCGC 
GTGTACGGGG ATGGGTCCGC ACGGATCCTG CACGTCTACA CCCGCGAGGG CTTCAGCTTC 
GAGGCCCTGC CGCCGCGCGC CAGCTGCGAA ACCCCCGCGT CCACACCGGA GGCCCACGAG 
CATGCTCCGG CGCACAGCAA CCCGAGCGGA CGCGCAGCAC TGGCCTCGCA GCTCTTGGAC 
CAGTCCGCTC TCTCGCCCGC TGGGGGCTCA GGACCGCAGA CGTGGTGGCG GCGGCGGCGC 
CGCTCCATCT CCCGGGCCCG CCAGGTGGAG CTGCTTCTGG TGGCTGACGC GTCCATGGCG 
CGGTTGTATG GCCGGGGCCT GCAGCATTAC CTGCTGACCC TGGCCTCCAT CGCCAATAGG 
CTGTACAGCC ATGCTAGCAT CGAGAACCAC ATCCGCCTGG CCGTGGTGAA GGTGGTGGTG 
CTAGGCGACA AGGACAAGAG CCTGGAAGTG AGCAAGAACG CTGCCACCAC ACTCAAGAAC 
TTTTGCAAGT GGCAGCACCA ACACAACCAG CTGGGAGATG ACCATGAGGA GCACTACGAT 
GCAGCTATCC TGTTTACTCG GGAGGATTTA TGTGGGCATC ATTCATGTGA CACCCTGGGA 
ATGGCAGACG TTGGGACCAT ATGTTCTCCA GAGCGCAGCT GTGCTGTGAT TGAAGACGAT 
GGCCTCCACG CAGCCTTCAC TGTGGCTCAC GAAATCGGAC ATTTACTTGG CCTCTCCCAT 
GACGATTCCA AATTCTGTGA AGAGACCTTT GGTTCCACAG AAGATAAGCG CTTAATGTCT 
TCCATCCTTA CCAGCATTGA TGCATCTAAG CCCTGGTCCA AATGCACTTC AGCCACCATC 
ACAGAATTCC TGGATGATGG CCATGGTAAC TGTTTGCTGG ACCTACCACG AAAGCAGATC 
CTGGGCCCCG AAGAACTCCC AGGACAGACC TACGATGCCA CCCAGCAGTG CAACCTGACA 
TTCGGGCCTG AGTACTCCGT GTGTCCCGGC ATGGATGTCT GTGCTCGCCT GTGGTGTGCT 
GTGGTACGCC AGGGCCAGAT GGTCTGTCTG ACCAAGAAGC TGCCTGCGGT GGAAGGGACG 
CCTTGTGGAA AGGGGAGAAT CTGCCTGCAG GGCAAATGTG TGGACAAAAC CAAGAAAAAA 
TATTATTCAA CGTCAAGCCA TGGCAACTGG GGATCTTGGG GATCCTGGGG CCAGTGTTCT 
CGCTCATGTG GAGGAGGAGT GCAGTTTGCC TATCGTCACT GTAATAACCC TGCTCCCAGA 
AACAACGGAC GCTACTGCAC AGGGAAGAGG GCCATCTACC GCTCCTGCAG TCTCATGCCC 
TGCCCACCCA ATGGTAAATC ATTTCGTCAT GAACAGTGTG AGGCCAAAAA TGGCTATCAG 
TCTGATGCAA AAGGAGTCAA AACTTTTGTG GAATGGGTTC CCAAATATGC AGGTGTCCTG 
CCAGCGGATG TGTGCAAGCT GACCTGCAGA GCCAAGGGCA CTGGCTACTA TGTGGTATTT 
TCTCCAAAGG TGACCGATGG CACTGAATGT AGGCTGTACA GTAATTCCGT CTGCGTCCGG 
GGGAAGTGTG TGAGAACTGG CTGTGACGGC ATCATTGGCT CAAAGCTGCA GTATGACAAG 
TGCGGAGTAT GTGGAGGAGA CAACTCCAGC TGTACAAAGA TTGTTGGAAC CTTTAATAAG 
AAAAGTAAGG GTTACACTGA CGTGGTGAGG ATTCCTGAAG GGGCAACCCA CATAAAAGTT 
CGACAGTTCA AAGCCAAAGA CCAGACTAGA TTCACTGCCT ATTTAGCCCT GAAAAAGAAA 
AACGGTGAGT ACCTTATCAA TGGAAAGTAC ATGATCTCCA CTTCAGAGAC TATCATTGAC 
ATCAATGGAA CAGTCATGAA CTATAGCGGT TGGAGCCACA GGGATGACTT CCTGCATGGC 
ATGGGCTACT CTGCCACGAA GGAAATTCTA ATAGTGCAGA TTCTTGCAAC AGACCCCACT 
AAACCATTAG ATGTCCGTTA TAGCTTTTTT GTTCCCAAGA AGTCCACTCC AAAAGTAAAC 
TCTGTCACTA GTCATGGCAG CAATAAAGTG GGATCACACA CTTCGCAGCC GCAGTGGGTC 
ACGGGCCCAT GGCTCGCCTG CTCTAGGACC TGTGACACAG GTTGGCACAC CAGAACGGTG 
CAGTGCCAGG ATGGAAACCG GAAGTTAGCA AAAGGATGTC CTCTCTCCCA AAGGCCTTCT 
GCGTTTAAGC AATGCTTGTT GAAGAAATGT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_008969.2
CDS	730..3522
Translation	MLLGWASLLLCAFRLPLAAVGPAATPAQDKAGQPPTAAAAAQPRRRQGEEVQERAEPPGHPHPLAQRRRSKGLVQNIDQLYSGGGKVGYLVYAGGRRFLLDLERDGSVGIAGFVPAGGGTSAPWRHRSHCFYRGTVDGSPRSLAVFDLCGGLDGFFAVKHARYTLKPLLRGPWAEEEKGRVYGDGSARILHVYTREGFSFEALPPRASCETPASTPEAHEHAPAHSNPSGRAALASQLLDQSALSPAGGSGPQTWWRRRRRSISRARQVELLLVADASMARLYGRGLQHYLLTLASIANRLYSHASIENHIRLAVVKVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSCDTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHLLGLSHDDSKFCEETFGSTEDKRLMSSILTSIDASKPWSKCTSATITEFLDDGHGNCLLDLPRKQILGPEELPGQTYDATQQCNLTFGPEYSVCPGMDVCARLWCAVVRQGQMVCLTKKLPAVEGTPCGKGRICLQGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPRNNGRYCTGKRAIYRSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGVLPADVCKLTCRAKGTGYYVVFSPKVTDGTECRLYSNSVCVRGKCVRTGCDGIIGSKLQYDKCGVCGGDNSSCTKIVGTFNKKSKGYTDVVRIPEGATHIKVRQFKAKDQTRFTAYLALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMGYSATKEILIVQILATDPTKPLDVRYSFFVPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGNRKLAKGCPLSQRPSAFKQCLLKKC

Target ORF information:

RefSeq Version	NM_007038.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007038.4

ORF Insert Sequence:

ATGCTGCTCG GGTGGGCGTC CCTGCTGCTG TGCGCGTTCC GCCTGCCCCT GGCCGCGGTC 
GGCCCCGCCG CGACACCTGC CCAGGATAAA GCCGGGCAGC CTCCGACTGC TGCAGCAGCC 
GCCCAGCCCC GCCGGCGGCA GGGGGAGGAG GTGCAGGAGC GAGCCGAGCC TCCCGGCCAC 
CCGCACCCCC TGGCGCAGCG GCGCAGGAGC AAGGGGCTGG TGCAGAACAT CGACCAACTC 
TACTCCGGCG GCGGCAAGGT GGGCTACCTC GTCTACGCGG GCGGCCGGAG GTTCCTCTTG 
GACCTGGAGC GAGATGGTTC GGTGGGCATT GCTGGCTTCG TGCCCGCAGG AGGCGGGACG 
AGTGCGCCCT GGCGCCACCG GAGCCACTGC TTCTATCGGG GCACAGTGGA CGGTAGTCCC 
CGCTCTCTGG CTGTCTTTGA CCTCTGTGGG GGTCTCGACG GCTTCTTCGC GGTCAAGCAC 
GCGCGCTACA CCCTAAAGCC ACTGCTGCGC GGACCCTGGG CGGAGGAAGA AAAGGGGCGC 
GTGTACGGGG ATGGGTCCGC ACGGATCCTG CACGTCTACA CCCGCGAGGG CTTCAGCTTC 
GAGGCCCTGC CGCCGCGCGC CAGCTGCGAA ACCCCCGCGT CCACACCGGA GGCCCACGAG 
CATGCTCCGG CGCACAGCAA CCCGAGCGGA CGCGCAGCAC TGGCCTCGCA GCTCTTGGAC 
CAGTCCGCTC TCTCGCCCGC TGGGGGCTCA GGACCGCAGA CGTGGTGGCG GCGGCGGCGC 
CGCTCCATCT CCCGGGCCCG CCAGGTGGAG CTGCTTCTGG TGGCTGACGC GTCCATGGCG 
CGGTTGTATG GCCGGGGCCT GCAGCATTAC CTGCTGACCC TGGCCTCCAT CGCCAATAGG 
CTGTACAGCC ATGCTAGCAT CGAGAACCAC ATCCGCCTGG CCGTGGTGAA GGTGGTGGTG 
CTAGGCGACA AGGACAAGAG CCTGGAAGTG AGCAAGAACG CTGCCACCAC ACTCAAGAAC 
TTTTGCAAGT GGCAGCACCA ACACAACCAG CTGGGAGATG ACCATGAGGA GCACTACGAT 
GCAGCTATCC TGTTTACTCG GGAGGATTTA TGTGGGCATC ATTCATGTGA CACCCTGGGA 
ATGGCAGACG TTGGGACCAT ATGTTCTCCA GAGCGCAGCT GTGCTGTGAT TGAAGACGAT 
GGCCTCCACG CAGCCTTCAC TGTGGCTCAC GAAATCGGAC ATTTACTTGG CCTCTCCCAT 
GACGATTCCA AATTCTGTGA AGAGACCTTT GGTTCCACAG AAGATAAGCG CTTAATGTCT 
TCCATCCTTA CCAGCATTGA TGCATCTAAG CCCTGGTCCA AATGCACTTC AGCCACCATC 
ACAGAATTCC TGGATGATGG CCATGGTAAC TGTTTGCTGG ACCTACCACG AAAGCAGATC 
CTGGGCCCCG AAGAACTCCC AGGACAGACC TACGATGCCA CCCAGCAGTG CAACCTGACA 
TTCGGGCCTG AGTACTCCGT GTGTCCCGGC ATGGATGTCT GTGCTCGCCT GTGGTGTGCT 
GTGGTACGCC AGGGCCAGAT GGTCTGTCTG ACCAAGAAGC TGCCTGCGGT GGAAGGGACG 
CCTTGTGGAA AGGGGAGAAT CTGCCTGCAG GGCAAATGTG TGGACAAAAC CAAGAAAAAA 
TATTATTCAA CGTCAAGCCA TGGCAACTGG GGATCTTGGG GATCCTGGGG CCAGTGTTCT 
CGCTCATGTG GAGGAGGAGT GCAGTTTGCC TATCGTCACT GTAATAACCC TGCTCCCAGA 
AACAACGGAC GCTACTGCAC AGGGAAGAGG GCCATCTACC GCTCCTGCAG TCTCATGCCC 
TGCCCACCCA ATGGTAAATC ATTTCGTCAT GAACAGTGTG AGGCCAAAAA TGGCTATCAG 
TCTGATGCAA AAGGAGTCAA AACTTTTGTG GAATGGGTTC CCAAATATGC AGGTGTCCTG 
CCAGCGGATG TGTGCAAGCT GACCTGCAGA GCCAAGGGCA CTGGCTACTA TGTGGTATTT 
TCTCCAAAGG TGACCGATGG CACTGAATGT AGGCTGTACA GTAATTCCGT CTGCGTCCGG 
GGGAAGTGTG TGAGAACTGG CTGTGACGGC ATCATTGGCT CAAAGCTGCA GTATGACAAG 
TGCGGAGTAT GTGGAGGAGA CAACTCCAGC TGTACAAAGA TTGTTGGAAC CTTTAATAAG 
AAAAGTAAGG GTTACACTGA CGTGGTGAGG ATTCCTGAAG GGGCAACCCA CATAAAAGTT 
CGACAGTTCA AAGCCAAAGA CCAGACTAGA TTCACTGCCT ATTTAGCCCT GAAAAAGAAA 
AACGGTGAGT ACCTTATCAA TGGAAAGTAC ATGATCTCCA CTTCAGAGAC TATCATTGAC 
ATCAATGGAA CAGTCATGAA CTATAGCGGT TGGAGCCACA GGGATGACTT CCTGCATGGC 
ATGGGCTACT CTGCCACGAA GGAAATTCTA ATAGTGCAGA TTCTTGCAAC AGACCCCACT 
AAACCATTAG ATGTCCGTTA TAGCTTTTTT GTTCCCAAGA AGTCCACTCC AAAAGTAAAC 
TCTGTCACTA GTCATGGCAG CAATAAAGTG GGATCACACA CTTCGCAGCC GCAGTGGGTC 
ACGGGCCCAT GGCTCGCCTG CTCTAGGACC TGTGACACAG GTTGGCACAC CAGAACGGTG 
CAGTGCCAGG ATGGAAACCG GAAGTTAGCA AAAGGATGTC CTCTCTCCCA AAGGCCTTCT 
GCGTTTAAGC AATGCTTGTT GAAGAAATGT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS5 ( NM_007038.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_008969.2 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5), mRNA.

Price & Availability↑

CloneID	OHu27335
Clone ID Related Accession (Same CDS sequence)	NM_007038.4 , NM_007038.5 , XM_024452053.1
Accession Version	NM_007038.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2793bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 5 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK094057.1, AP001601.1, AF142099.1, AP001600.1 and CA313018.1. On Nov 22, 2018 this sequence version replaced NM_007038.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF142099.1, SRR1660807.260679.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000284987.6/ ENSP00000284987.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCTGCTCG GGTGGGCGTC CCTGCTGCTG TGCGCGTTCC GCCTGCCCCT GGCCGCGGTC 
GGCCCCGCCG CGACACCTGC CCAGGATAAA GCCGGGCAGC CTCCGACTGC TGCAGCAGCC 
GCCCAGCCCC GCCGGCGGCA GGGGGAGGAG GTGCAGGAGC GAGCCGAGCC TCCCGGCCAC 
CCGCACCCCC TGGCGCAGCG GCGCAGGAGC AAGGGGCTGG TGCAGAACAT CGACCAACTC 
TACTCCGGCG GCGGCAAGGT GGGCTACCTC GTCTACGCGG GCGGCCGGAG GTTCCTCTTG 
GACCTGGAGC GAGATGGTTC GGTGGGCATT GCTGGCTTCG TGCCCGCAGG AGGCGGGACG 
AGTGCGCCCT GGCGCCACCG GAGCCACTGC TTCTATCGGG GCACAGTGGA CGGTAGTCCC 
CGCTCTCTGG CTGTCTTTGA CCTCTGTGGG GGTCTCGACG GCTTCTTCGC GGTCAAGCAC 
GCGCGCTACA CCCTAAAGCC ACTGCTGCGC GGACCCTGGG CGGAGGAAGA AAAGGGGCGC 
GTGTACGGGG ATGGGTCCGC ACGGATCCTG CACGTCTACA CCCGCGAGGG CTTCAGCTTC 
GAGGCCCTGC CGCCGCGCGC CAGCTGCGAA ACCCCCGCGT CCACACCGGA GGCCCACGAG 
CATGCTCCGG CGCACAGCAA CCCGAGCGGA CGCGCAGCAC TGGCCTCGCA GCTCTTGGAC 
CAGTCCGCTC TCTCGCCCGC TGGGGGCTCA GGACCGCAGA CGTGGTGGCG GCGGCGGCGC 
CGCTCCATCT CCCGGGCCCG CCAGGTGGAG CTGCTTCTGG TGGCTGACGC GTCCATGGCG 
CGGTTGTATG GCCGGGGCCT GCAGCATTAC CTGCTGACCC TGGCCTCCAT CGCCAATAGG 
CTGTACAGCC ATGCTAGCAT CGAGAACCAC ATCCGCCTGG CCGTGGTGAA GGTGGTGGTG 
CTAGGCGACA AGGACAAGAG CCTGGAAGTG AGCAAGAACG CTGCCACCAC ACTCAAGAAC 
TTTTGCAAGT GGCAGCACCA ACACAACCAG CTGGGAGATG ACCATGAGGA GCACTACGAT 
GCAGCTATCC TGTTTACTCG GGAGGATTTA TGTGGGCATC ATTCATGTGA CACCCTGGGA 
ATGGCAGACG TTGGGACCAT ATGTTCTCCA GAGCGCAGCT GTGCTGTGAT TGAAGACGAT 
GGCCTCCACG CAGCCTTCAC TGTGGCTCAC GAAATCGGAC ATTTACTTGG CCTCTCCCAT 
GACGATTCCA AATTCTGTGA AGAGACCTTT GGTTCCACAG AAGATAAGCG CTTAATGTCT 
TCCATCCTTA CCAGCATTGA TGCATCTAAG CCCTGGTCCA AATGCACTTC AGCCACCATC 
ACAGAATTCC TGGATGATGG CCATGGTAAC TGTTTGCTGG ACCTACCACG AAAGCAGATC 
CTGGGCCCCG AAGAACTCCC AGGACAGACC TACGATGCCA CCCAGCAGTG CAACCTGACA 
TTCGGGCCTG AGTACTCCGT GTGTCCCGGC ATGGATGTCT GTGCTCGCCT GTGGTGTGCT 
GTGGTACGCC AGGGCCAGAT GGTCTGTCTG ACCAAGAAGC TGCCTGCGGT GGAAGGGACG 
CCTTGTGGAA AGGGGAGAAT CTGCCTGCAG GGCAAATGTG TGGACAAAAC CAAGAAAAAA 
TATTATTCAA CGTCAAGCCA TGGCAACTGG GGATCTTGGG GATCCTGGGG CCAGTGTTCT 
CGCTCATGTG GAGGAGGAGT GCAGTTTGCC TATCGTCACT GTAATAACCC TGCTCCCAGA 
AACAACGGAC GCTACTGCAC AGGGAAGAGG GCCATCTACC GCTCCTGCAG TCTCATGCCC 
TGCCCACCCA ATGGTAAATC ATTTCGTCAT GAACAGTGTG AGGCCAAAAA TGGCTATCAG 
TCTGATGCAA AAGGAGTCAA AACTTTTGTG GAATGGGTTC CCAAATATGC AGGTGTCCTG 
CCAGCGGATG TGTGCAAGCT GACCTGCAGA GCCAAGGGCA CTGGCTACTA TGTGGTATTT 
TCTCCAAAGG TGACCGATGG CACTGAATGT AGGCTGTACA GTAATTCCGT CTGCGTCCGG 
GGGAAGTGTG TGAGAACTGG CTGTGACGGC ATCATTGGCT CAAAGCTGCA GTATGACAAG 
TGCGGAGTAT GTGGAGGAGA CAACTCCAGC TGTACAAAGA TTGTTGGAAC CTTTAATAAG 
AAAAGTAAGG GTTACACTGA CGTGGTGAGG ATTCCTGAAG GGGCAACCCA CATAAAAGTT 
CGACAGTTCA AAGCCAAAGA CCAGACTAGA TTCACTGCCT ATTTAGCCCT GAAAAAGAAA 
AACGGTGAGT ACCTTATCAA TGGAAAGTAC ATGATCTCCA CTTCAGAGAC TATCATTGAC 
ATCAATGGAA CAGTCATGAA CTATAGCGGT TGGAGCCACA GGGATGACTT CCTGCATGGC 
ATGGGCTACT CTGCCACGAA GGAAATTCTA ATAGTGCAGA TTCTTGCAAC AGACCCCACT 
AAACCATTAG ATGTCCGTTA TAGCTTTTTT GTTCCCAAGA AGTCCACTCC AAAAGTAAAC 
TCTGTCACTA GTCATGGCAG CAATAAAGTG GGATCACACA CTTCGCAGCC GCAGTGGGTC 
ACGGGCCCAT GGCTCGCCTG CTCTAGGACC TGTGACACAG GTTGGCACAC CAGAACGGTG 
CAGTGCCAGG ATGGAAACCG GAAGTTAGCA AAAGGATGTC CTCTCTCCCA AAGGCCTTCT 
GCGTTTAAGC AATGCTTGTT GAAGAAATGT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_008969.2
CDS	698..3490
Translation	MLLGWASLLLCAFRLPLAAVGPAATPAQDKAGQPPTAAAAAQPRRRQGEEVQERAEPPGHPHPLAQRRRSKGLVQNIDQLYSGGGKVGYLVYAGGRRFLLDLERDGSVGIAGFVPAGGGTSAPWRHRSHCFYRGTVDGSPRSLAVFDLCGGLDGFFAVKHARYTLKPLLRGPWAEEEKGRVYGDGSARILHVYTREGFSFEALPPRASCETPASTPEAHEHAPAHSNPSGRAALASQLLDQSALSPAGGSGPQTWWRRRRRSISRARQVELLLVADASMARLYGRGLQHYLLTLASIANRLYSHASIENHIRLAVVKVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSCDTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHLLGLSHDDSKFCEETFGSTEDKRLMSSILTSIDASKPWSKCTSATITEFLDDGHGNCLLDLPRKQILGPEELPGQTYDATQQCNLTFGPEYSVCPGMDVCARLWCAVVRQGQMVCLTKKLPAVEGTPCGKGRICLQGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPRNNGRYCTGKRAIYRSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGVLPADVCKLTCRAKGTGYYVVFSPKVTDGTECRLYSNSVCVRGKCVRTGCDGIIGSKLQYDKCGVCGGDNSSCTKIVGTFNKKSKGYTDVVRIPEGATHIKVRQFKAKDQTRFTAYLALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMGYSATKEILIVQILATDPTKPLDVRYSFFVPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGNRKLAKGCPLSQRPSAFKQCLLKKC

Target ORF information:

RefSeq Version	NM_007038.5
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007038.5

ORF Insert Sequence:

ATGCTGCTCG GGTGGGCGTC CCTGCTGCTG TGCGCGTTCC GCCTGCCCCT GGCCGCGGTC 
GGCCCCGCCG CGACACCTGC CCAGGATAAA GCCGGGCAGC CTCCGACTGC TGCAGCAGCC 
GCCCAGCCCC GCCGGCGGCA GGGGGAGGAG GTGCAGGAGC GAGCCGAGCC TCCCGGCCAC 
CCGCACCCCC TGGCGCAGCG GCGCAGGAGC AAGGGGCTGG TGCAGAACAT CGACCAACTC 
TACTCCGGCG GCGGCAAGGT GGGCTACCTC GTCTACGCGG GCGGCCGGAG GTTCCTCTTG 
GACCTGGAGC GAGATGGTTC GGTGGGCATT GCTGGCTTCG TGCCCGCAGG AGGCGGGACG 
AGTGCGCCCT GGCGCCACCG GAGCCACTGC TTCTATCGGG GCACAGTGGA CGGTAGTCCC 
CGCTCTCTGG CTGTCTTTGA CCTCTGTGGG GGTCTCGACG GCTTCTTCGC GGTCAAGCAC 
GCGCGCTACA CCCTAAAGCC ACTGCTGCGC GGACCCTGGG CGGAGGAAGA AAAGGGGCGC 
GTGTACGGGG ATGGGTCCGC ACGGATCCTG CACGTCTACA CCCGCGAGGG CTTCAGCTTC 
GAGGCCCTGC CGCCGCGCGC CAGCTGCGAA ACCCCCGCGT CCACACCGGA GGCCCACGAG 
CATGCTCCGG CGCACAGCAA CCCGAGCGGA CGCGCAGCAC TGGCCTCGCA GCTCTTGGAC 
CAGTCCGCTC TCTCGCCCGC TGGGGGCTCA GGACCGCAGA CGTGGTGGCG GCGGCGGCGC 
CGCTCCATCT CCCGGGCCCG CCAGGTGGAG CTGCTTCTGG TGGCTGACGC GTCCATGGCG 
CGGTTGTATG GCCGGGGCCT GCAGCATTAC CTGCTGACCC TGGCCTCCAT CGCCAATAGG 
CTGTACAGCC ATGCTAGCAT CGAGAACCAC ATCCGCCTGG CCGTGGTGAA GGTGGTGGTG 
CTAGGCGACA AGGACAAGAG CCTGGAAGTG AGCAAGAACG CTGCCACCAC ACTCAAGAAC 
TTTTGCAAGT GGCAGCACCA ACACAACCAG CTGGGAGATG ACCATGAGGA GCACTACGAT 
GCAGCTATCC TGTTTACTCG GGAGGATTTA TGTGGGCATC ATTCATGTGA CACCCTGGGA 
ATGGCAGACG TTGGGACCAT ATGTTCTCCA GAGCGCAGCT GTGCTGTGAT TGAAGACGAT 
GGCCTCCACG CAGCCTTCAC TGTGGCTCAC GAAATCGGAC ATTTACTTGG CCTCTCCCAT 
GACGATTCCA AATTCTGTGA AGAGACCTTT GGTTCCACAG AAGATAAGCG CTTAATGTCT 
TCCATCCTTA CCAGCATTGA TGCATCTAAG CCCTGGTCCA AATGCACTTC AGCCACCATC 
ACAGAATTCC TGGATGATGG CCATGGTAAC TGTTTGCTGG ACCTACCACG AAAGCAGATC 
CTGGGCCCCG AAGAACTCCC AGGACAGACC TACGATGCCA CCCAGCAGTG CAACCTGACA 
TTCGGGCCTG AGTACTCCGT GTGTCCCGGC ATGGATGTCT GTGCTCGCCT GTGGTGTGCT 
GTGGTACGCC AGGGCCAGAT GGTCTGTCTG ACCAAGAAGC TGCCTGCGGT GGAAGGGACG 
CCTTGTGGAA AGGGGAGAAT CTGCCTGCAG GGCAAATGTG TGGACAAAAC CAAGAAAAAA 
TATTATTCAA CGTCAAGCCA TGGCAACTGG GGATCTTGGG GATCCTGGGG CCAGTGTTCT 
CGCTCATGTG GAGGAGGAGT GCAGTTTGCC TATCGTCACT GTAATAACCC TGCTCCCAGA 
AACAACGGAC GCTACTGCAC AGGGAAGAGG GCCATCTACC GCTCCTGCAG TCTCATGCCC 
TGCCCACCCA ATGGTAAATC ATTTCGTCAT GAACAGTGTG AGGCCAAAAA TGGCTATCAG 
TCTGATGCAA AAGGAGTCAA AACTTTTGTG GAATGGGTTC CCAAATATGC AGGTGTCCTG 
CCAGCGGATG TGTGCAAGCT GACCTGCAGA GCCAAGGGCA CTGGCTACTA TGTGGTATTT 
TCTCCAAAGG TGACCGATGG CACTGAATGT AGGCTGTACA GTAATTCCGT CTGCGTCCGG 
GGGAAGTGTG TGAGAACTGG CTGTGACGGC ATCATTGGCT CAAAGCTGCA GTATGACAAG 
TGCGGAGTAT GTGGAGGAGA CAACTCCAGC TGTACAAAGA TTGTTGGAAC CTTTAATAAG 
AAAAGTAAGG GTTACACTGA CGTGGTGAGG ATTCCTGAAG GGGCAACCCA CATAAAAGTT 
CGACAGTTCA AAGCCAAAGA CCAGACTAGA TTCACTGCCT ATTTAGCCCT GAAAAAGAAA 
AACGGTGAGT ACCTTATCAA TGGAAAGTAC ATGATCTCCA CTTCAGAGAC TATCATTGAC 
ATCAATGGAA CAGTCATGAA CTATAGCGGT TGGAGCCACA GGGATGACTT CCTGCATGGC 
ATGGGCTACT CTGCCACGAA GGAAATTCTA ATAGTGCAGA TTCTTGCAAC AGACCCCACT 
AAACCATTAG ATGTCCGTTA TAGCTTTTTT GTTCCCAAGA AGTCCACTCC AAAAGTAAAC 
TCTGTCACTA GTCATGGCAG CAATAAAGTG GGATCACACA CTTCGCAGCC GCAGTGGGTC 
ACGGGCCCAT GGCTCGCCTG CTCTAGGACC TGTGACACAG GTTGGCACAC CAGAACGGTG 
CAGTGCCAGG ATGGAAACCG GAAGTTAGCA AAAGGATGTC CTCTCTCCCA AAGGCCTTCT 
GCGTTTAAGC AATGCTTGTT GAAGAAATGT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS5 ( XM_024452053.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024307821.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu27335
Clone ID Related Accession (Same CDS sequence)	NM_007038.4 , NM_007038.5 , XM_024452053.1
Accession Version	XM_024452053.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2793bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000021.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGCTCG GGTGGGCGTC CCTGCTGCTG TGCGCGTTCC GCCTGCCCCT GGCCGCGGTC 
GGCCCCGCCG CGACACCTGC CCAGGATAAA GCCGGGCAGC CTCCGACTGC TGCAGCAGCC 
GCCCAGCCCC GCCGGCGGCA GGGGGAGGAG GTGCAGGAGC GAGCCGAGCC TCCCGGCCAC 
CCGCACCCCC TGGCGCAGCG GCGCAGGAGC AAGGGGCTGG TGCAGAACAT CGACCAACTC 
TACTCCGGCG GCGGCAAGGT GGGCTACCTC GTCTACGCGG GCGGCCGGAG GTTCCTCTTG 
GACCTGGAGC GAGATGGTTC GGTGGGCATT GCTGGCTTCG TGCCCGCAGG AGGCGGGACG 
AGTGCGCCCT GGCGCCACCG GAGCCACTGC TTCTATCGGG GCACAGTGGA CGGTAGTCCC 
CGCTCTCTGG CTGTCTTTGA CCTCTGTGGG GGTCTCGACG GCTTCTTCGC GGTCAAGCAC 
GCGCGCTACA CCCTAAAGCC ACTGCTGCGC GGACCCTGGG CGGAGGAAGA AAAGGGGCGC 
GTGTACGGGG ATGGGTCCGC ACGGATCCTG CACGTCTACA CCCGCGAGGG CTTCAGCTTC 
GAGGCCCTGC CGCCGCGCGC CAGCTGCGAA ACCCCCGCGT CCACACCGGA GGCCCACGAG 
CATGCTCCGG CGCACAGCAA CCCGAGCGGA CGCGCAGCAC TGGCCTCGCA GCTCTTGGAC 
CAGTCCGCTC TCTCGCCCGC TGGGGGCTCA GGACCGCAGA CGTGGTGGCG GCGGCGGCGC 
CGCTCCATCT CCCGGGCCCG CCAGGTGGAG CTGCTTCTGG TGGCTGACGC GTCCATGGCG 
CGGTTGTATG GCCGGGGCCT GCAGCATTAC CTGCTGACCC TGGCCTCCAT CGCCAATAGG 
CTGTACAGCC ATGCTAGCAT CGAGAACCAC ATCCGCCTGG CCGTGGTGAA GGTGGTGGTG 
CTAGGCGACA AGGACAAGAG CCTGGAAGTG AGCAAGAACG CTGCCACCAC ACTCAAGAAC 
TTTTGCAAGT GGCAGCACCA ACACAACCAG CTGGGAGATG ACCATGAGGA GCACTACGAT 
GCAGCTATCC TGTTTACTCG GGAGGATTTA TGTGGGCATC ATTCATGTGA CACCCTGGGA 
ATGGCAGACG TTGGGACCAT ATGTTCTCCA GAGCGCAGCT GTGCTGTGAT TGAAGACGAT 
GGCCTCCACG CAGCCTTCAC TGTGGCTCAC GAAATCGGAC ATTTACTTGG CCTCTCCCAT 
GACGATTCCA AATTCTGTGA AGAGACCTTT GGTTCCACAG AAGATAAGCG CTTAATGTCT 
TCCATCCTTA CCAGCATTGA TGCATCTAAG CCCTGGTCCA AATGCACTTC AGCCACCATC 
ACAGAATTCC TGGATGATGG CCATGGTAAC TGTTTGCTGG ACCTACCACG AAAGCAGATC 
CTGGGCCCCG AAGAACTCCC AGGACAGACC TACGATGCCA CCCAGCAGTG CAACCTGACA 
TTCGGGCCTG AGTACTCCGT GTGTCCCGGC ATGGATGTCT GTGCTCGCCT GTGGTGTGCT 
GTGGTACGCC AGGGCCAGAT GGTCTGTCTG ACCAAGAAGC TGCCTGCGGT GGAAGGGACG 
CCTTGTGGAA AGGGGAGAAT CTGCCTGCAG GGCAAATGTG TGGACAAAAC CAAGAAAAAA 
TATTATTCAA CGTCAAGCCA TGGCAACTGG GGATCTTGGG GATCCTGGGG CCAGTGTTCT 
CGCTCATGTG GAGGAGGAGT GCAGTTTGCC TATCGTCACT GTAATAACCC TGCTCCCAGA 
AACAACGGAC GCTACTGCAC AGGGAAGAGG GCCATCTACC GCTCCTGCAG TCTCATGCCC 
TGCCCACCCA ATGGTAAATC ATTTCGTCAT GAACAGTGTG AGGCCAAAAA TGGCTATCAG 
TCTGATGCAA AAGGAGTCAA AACTTTTGTG GAATGGGTTC CCAAATATGC AGGTGTCCTG 
CCAGCGGATG TGTGCAAGCT GACCTGCAGA GCCAAGGGCA CTGGCTACTA TGTGGTATTT 
TCTCCAAAGG TGACCGATGG CACTGAATGT AGGCTGTACA GTAATTCCGT CTGCGTCCGG 
GGGAAGTGTG TGAGAACTGG CTGTGACGGC ATCATTGGCT CAAAGCTGCA GTATGACAAG 
TGCGGAGTAT GTGGAGGAGA CAACTCCAGC TGTACAAAGA TTGTTGGAAC CTTTAATAAG 
AAAAGTAAGG GTTACACTGA CGTGGTGAGG ATTCCTGAAG GGGCAACCCA CATAAAAGTT 
CGACAGTTCA AAGCCAAAGA CCAGACTAGA TTCACTGCCT ATTTAGCCCT GAAAAAGAAA 
AACGGTGAGT ACCTTATCAA TGGAAAGTAC ATGATCTCCA CTTCAGAGAC TATCATTGAC 
ATCAATGGAA CAGTCATGAA CTATAGCGGT TGGAGCCACA GGGATGACTT CCTGCATGGC 
ATGGGCTACT CTGCCACGAA GGAAATTCTA ATAGTGCAGA TTCTTGCAAC AGACCCCACT 
AAACCATTAG ATGTCCGTTA TAGCTTTTTT GTTCCCAAGA AGTCCACTCC AAAAGTAAAC 
TCTGTCACTA GTCATGGCAG CAATAAAGTG GGATCACACA CTTCGCAGCC GCAGTGGGTC 
ACGGGCCCAT GGCTCGCCTG CTCTAGGACC TGTGACACAG GTTGGCACAC CAGAACGGTG 
CAGTGCCAGG ATGGAAACCG GAAGTTAGCA AAAGGATGTC CTCTCTCCCA AAGGCCTTCT 
GCGTTTAAGC AATGCTTGTT GAAGAAATGT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024307821.1
CDS	1046..3838
Translation	MLLGWASLLLCAFRLPLAAVGPAATPAQDKAGQPPTAAAAAQPRRRQGEEVQERAEPPGHPHPLAQRRRSKGLVQNIDQLYSGGGKVGYLVYAGGRRFLLDLERDGSVGIAGFVPAGGGTSAPWRHRSHCFYRGTVDGSPRSLAVFDLCGGLDGFFAVKHARYTLKPLLRGPWAEEEKGRVYGDGSARILHVYTREGFSFEALPPRASCETPASTPEAHEHAPAHSNPSGRAALASQLLDQSALSPAGGSGPQTWWRRRRRSISRARQVELLLVADASMARLYGRGLQHYLLTLASIANRLYSHASIENHIRLAVVKVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSCDTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHLLGLSHDDSKFCEETFGSTEDKRLMSSILTSIDASKPWSKCTSATITEFLDDGHGNCLLDLPRKQILGPEELPGQTYDATQQCNLTFGPEYSVCPGMDVCARLWCAVVRQGQMVCLTKKLPAVEGTPCGKGRICLQGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPRNNGRYCTGKRAIYRSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGVLPADVCKLTCRAKGTGYYVVFSPKVTDGTECRLYSNSVCVRGKCVRTGCDGIIGSKLQYDKCGVCGGDNSSCTKIVGTFNKKSKGYTDVVRIPEGATHIKVRQFKAKDQTRFTAYLALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMGYSATKEILIVQILATDPTKPLDVRYSFFVPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGNRKLAKGCPLSQRPSAFKQCLLKKC

Target ORF information:

RefSeq Version	XM_024452053.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024452053.1

ORF Insert Sequence:

ATGCTGCTCG GGTGGGCGTC CCTGCTGCTG TGCGCGTTCC GCCTGCCCCT GGCCGCGGTC 
GGCCCCGCCG CGACACCTGC CCAGGATAAA GCCGGGCAGC CTCCGACTGC TGCAGCAGCC 
GCCCAGCCCC GCCGGCGGCA GGGGGAGGAG GTGCAGGAGC GAGCCGAGCC TCCCGGCCAC 
CCGCACCCCC TGGCGCAGCG GCGCAGGAGC AAGGGGCTGG TGCAGAACAT CGACCAACTC 
TACTCCGGCG GCGGCAAGGT GGGCTACCTC GTCTACGCGG GCGGCCGGAG GTTCCTCTTG 
GACCTGGAGC GAGATGGTTC GGTGGGCATT GCTGGCTTCG TGCCCGCAGG AGGCGGGACG 
AGTGCGCCCT GGCGCCACCG GAGCCACTGC TTCTATCGGG GCACAGTGGA CGGTAGTCCC 
CGCTCTCTGG CTGTCTTTGA CCTCTGTGGG GGTCTCGACG GCTTCTTCGC GGTCAAGCAC 
GCGCGCTACA CCCTAAAGCC ACTGCTGCGC GGACCCTGGG CGGAGGAAGA AAAGGGGCGC 
GTGTACGGGG ATGGGTCCGC ACGGATCCTG CACGTCTACA CCCGCGAGGG CTTCAGCTTC 
GAGGCCCTGC CGCCGCGCGC CAGCTGCGAA ACCCCCGCGT CCACACCGGA GGCCCACGAG 
CATGCTCCGG CGCACAGCAA CCCGAGCGGA CGCGCAGCAC TGGCCTCGCA GCTCTTGGAC 
CAGTCCGCTC TCTCGCCCGC TGGGGGCTCA GGACCGCAGA CGTGGTGGCG GCGGCGGCGC 
CGCTCCATCT CCCGGGCCCG CCAGGTGGAG CTGCTTCTGG TGGCTGACGC GTCCATGGCG 
CGGTTGTATG GCCGGGGCCT GCAGCATTAC CTGCTGACCC TGGCCTCCAT CGCCAATAGG 
CTGTACAGCC ATGCTAGCAT CGAGAACCAC ATCCGCCTGG CCGTGGTGAA GGTGGTGGTG 
CTAGGCGACA AGGACAAGAG CCTGGAAGTG AGCAAGAACG CTGCCACCAC ACTCAAGAAC 
TTTTGCAAGT GGCAGCACCA ACACAACCAG CTGGGAGATG ACCATGAGGA GCACTACGAT 
GCAGCTATCC TGTTTACTCG GGAGGATTTA TGTGGGCATC ATTCATGTGA CACCCTGGGA 
ATGGCAGACG TTGGGACCAT ATGTTCTCCA GAGCGCAGCT GTGCTGTGAT TGAAGACGAT 
GGCCTCCACG CAGCCTTCAC TGTGGCTCAC GAAATCGGAC ATTTACTTGG CCTCTCCCAT 
GACGATTCCA AATTCTGTGA AGAGACCTTT GGTTCCACAG AAGATAAGCG CTTAATGTCT 
TCCATCCTTA CCAGCATTGA TGCATCTAAG CCCTGGTCCA AATGCACTTC AGCCACCATC 
ACAGAATTCC TGGATGATGG CCATGGTAAC TGTTTGCTGG ACCTACCACG AAAGCAGATC 
CTGGGCCCCG AAGAACTCCC AGGACAGACC TACGATGCCA CCCAGCAGTG CAACCTGACA 
TTCGGGCCTG AGTACTCCGT GTGTCCCGGC ATGGATGTCT GTGCTCGCCT GTGGTGTGCT 
GTGGTACGCC AGGGCCAGAT GGTCTGTCTG ACCAAGAAGC TGCCTGCGGT GGAAGGGACG 
CCTTGTGGAA AGGGGAGAAT CTGCCTGCAG GGCAAATGTG TGGACAAAAC CAAGAAAAAA 
TATTATTCAA CGTCAAGCCA TGGCAACTGG GGATCTTGGG GATCCTGGGG CCAGTGTTCT 
CGCTCATGTG GAGGAGGAGT GCAGTTTGCC TATCGTCACT GTAATAACCC TGCTCCCAGA 
AACAACGGAC GCTACTGCAC AGGGAAGAGG GCCATCTACC GCTCCTGCAG TCTCATGCCC 
TGCCCACCCA ATGGTAAATC ATTTCGTCAT GAACAGTGTG AGGCCAAAAA TGGCTATCAG 
TCTGATGCAA AAGGAGTCAA AACTTTTGTG GAATGGGTTC CCAAATATGC AGGTGTCCTG 
CCAGCGGATG TGTGCAAGCT GACCTGCAGA GCCAAGGGCA CTGGCTACTA TGTGGTATTT 
TCTCCAAAGG TGACCGATGG CACTGAATGT AGGCTGTACA GTAATTCCGT CTGCGTCCGG 
GGGAAGTGTG TGAGAACTGG CTGTGACGGC ATCATTGGCT CAAAGCTGCA GTATGACAAG 
TGCGGAGTAT GTGGAGGAGA CAACTCCAGC TGTACAAAGA TTGTTGGAAC CTTTAATAAG 
AAAAGTAAGG GTTACACTGA CGTGGTGAGG ATTCCTGAAG GGGCAACCCA CATAAAAGTT 
CGACAGTTCA AAGCCAAAGA CCAGACTAGA TTCACTGCCT ATTTAGCCCT GAAAAAGAAA 
AACGGTGAGT ACCTTATCAA TGGAAAGTAC ATGATCTCCA CTTCAGAGAC TATCATTGAC 
ATCAATGGAA CAGTCATGAA CTATAGCGGT TGGAGCCACA GGGATGACTT CCTGCATGGC 
ATGGGCTACT CTGCCACGAA GGAAATTCTA ATAGTGCAGA TTCTTGCAAC AGACCCCACT 
AAACCATTAG ATGTCCGTTA TAGCTTTTTT GTTCCCAAGA AGTCCACTCC AAAAGTAAAC 
TCTGTCACTA GTCATGGCAG CAATAAAGTG GGATCACACA CTTCGCAGCC GCAGTGGGTC 
ACGGGCCCAT GGCTCGCCTG CTCTAGGACC TGTGACACAG GTTGGCACAC CAGAACGGTG 
CAGTGCCAGG ATGGAAACCG GAAGTTAGCA AAAGGATGTC CTCTCTCCCA AAGGCCTTCT 
GCGTTTAAGC AATGCTTGTT GAAGAAATGT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS5 ( XM_011529448.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011527750.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu64714
Clone ID Related Accession (Same CDS sequence)	XM_011529448.2 , XM_024452054.1
Accession Version	XM_011529448.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2625bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000021.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011529448.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGCTCG GGTGGGCGTC CCTGCTGCTG TGCGCGTTCC GCCTGCCCCT GGCCGCGGTC 
GGCCCCGCCG CGACACCTGC CCAGGATAAA GCCGGGCAGC CTCCGACTGC TGCAGCAGCC 
GCCCAGCCCC GCCGGCGGCA GGGGGAGGAG GTGCAGGAGC GAGCCGAGCC TCCCGGCCAC 
CCGCACCCCC TGGCGCAGCG GCGCAGGAGC AAGGGGCTGG TGCAGAACAT CGACCAACTC 
TACTCCGGCG GCGGCAAGGT GGGCTACCTC GTCTACGCGG GCGGCCGGAG GTTCCTCTTG 
GACCTGGAGC GAGATGGTTC GGTGGGCATT GCTGGCTTCG TGCCCGCAGG AGGCGGGACG 
AGTGCGCCCT GGCGCCACCG GAGCCACTGC TTCTATCGGG GCACAGTGGA CGGTAGTCCC 
CGCTCTCTGG CTGTCTTTGA CCTCTGTGGG GGTCTCGACG GCTTCTTCGC GGTCAAGCAC 
GCGCGCTACA CCCTAAAGCC ACTGCTGCGC GGACCCTGGG CGGAGGAAGA AAAGGGGCGC 
GTGTACGGGG ATGGGTCCGC ACGGATCCTG CACGTCTACA CCCGCGAGGG CTTCAGCTTC 
GAGGCCCTGC CGCCGCGCGC CAGCTGCGAA ACCCCCGCGT CCACACCGGA GGCCCACGAG 
CATGCTCCGG CGCACAGCAA CCCGAGCGGA CGCGCAGCAC TGGCCTCGCA GCTCTTGGAC 
CAGTCCGCTC TCTCGCCCGC TGGGGGCTCA GGACCGCAGA CGTGGTGGCG GCGGCGGCGC 
CGCTCCATCT CCCGGGCCCG CCAGGTGGAG CTGCTTCTGG TGGCTGACGC GTCCATGGCG 
CGGTTGTATG GCCGGGGCCT GCAGCATTAC CTGCTGACCC TGGCCTCCAT CGCCAATAGG 
CTGTACAGCC ATGCTAGCAT CGAGAACCAC ATCCGCCTGG CCGTGGTGAA GGTGGTGGTG 
CTAGGCGACA AGGACAAGAG CCTGGAAGTG AGCAAGAACG CTGCCACCAC ACTCAAGAAC 
TTTTGCAAGT GGCAGCACCA ACACAACCAG CTGGGAGATG ACCATGAGGA GCACTACGAT 
GCAGCTATCC TGTTTACTCG GGAGGATTTA TGTGGGCATC ATTCATGTGA CACCCTGGGA 
ATGGCAGACG TTGGGACCAT ATGTTCTCCA GAGCGCAGCT GTGCTGTGAT TGAAGACGAT 
GGCCTCCACG CAGCCTTCAC TGTGGCTCAC GAAATCGGTA ACTGTTTGCT GGACCTACCA 
CGAAAGCAGA TCCTGGGCCC CGAAGAACTC CCAGGACAGA CCTACGATGC CACCCAGCAG 
TGCAACCTGA CATTCGGGCC TGAGTACTCC GTGTGTCCCG GCATGGATGT CTGTGCTCGC 
CTGTGGTGTG CTGTGGTACG CCAGGGCCAG ATGGTCTGTC TGACCAAGAA GCTGCCTGCG 
GTGGAAGGGA CGCCTTGTGG AAAGGGGAGA ATCTGCCTGC AGGGCAAATG TGTGGACAAA 
ACCAAGAAAA AATATTATTC AACGTCAAGC CATGGCAACT GGGGATCTTG GGGATCCTGG 
GGCCAGTGTT CTCGCTCATG TGGAGGAGGA GTGCAGTTTG CCTATCGTCA CTGTAATAAC 
CCTGCTCCCA GAAACAACGG ACGCTACTGC ACAGGGAAGA GGGCCATCTA CCGCTCCTGC 
AGTCTCATGC CCTGCCCACC CAATGGTAAA TCATTTCGTC ATGAACAGTG TGAGGCCAAA 
AATGGCTATC AGTCTGATGC AAAAGGAGTC AAAACTTTTG TGGAATGGGT TCCCAAATAT 
GCAGGTGTCC TGCCAGCGGA TGTGTGCAAG CTGACCTGCA GAGCCAAGGG CACTGGCTAC 
TATGTGGTAT TTTCTCCAAA GGTGACCGAT GGCACTGAAT GTAGGCTGTA CAGTAATTCC 
GTCTGCGTCC GGGGGAAGTG TGTGAGAACT GGCTGTGACG GCATCATTGG CTCAAAGCTG 
CAGTATGACA AGTGCGGAGT ATGTGGAGGA GACAACTCCA GCTGTACAAA GATTGTTGGA 
ACCTTTAATA AGAAAAGTAA GGGTTACACT GACGTGGTGA GGATTCCTGA AGGGGCAACC 
CACATAAAAG TTCGACAGTT CAAAGCCAAA GACCAGACTA GATTCACTGC CTATTTAGCC 
CTGAAAAAGA AAAACGGTGA GTACCTTATC AATGGAAAGT ACATGATCTC CACTTCAGAG 
ACTATCATTG ACATCAATGG AACAGTCATG AACTATAGCG GTTGGAGCCA CAGGGATGAC 
TTCCTGCATG GCATGGGCTA CTCTGCCACG AAGGAAATTC TAATAGTGCA GATTCTTGCA 
ACAGACCCCA CTAAACCATT AGATGTCCGT TATAGCTTTT TTGTTCCCAA GAAGTCCACT 
CCAAAAGTAA ACTCTGTCAC TAGTCATGGC AGCAATAAAG TGGGATCACA CACTTCGCAG 
CCGCAGTGGG TCACGGGCCC ATGGCTCGCC TGCTCTAGGA CCTGTGACAC AGGTTGGCAC 
ACCAGAACGG TGCAGTGCCA GGATGGAAAC CGGAAGTTAG CAAAAGGATG TCCTCTCTCC 
CAAAGGCCTT CTGCGTTTAA GCAATGCTTG TTGAAGAAAT GTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011527750.1
CDS	730..3354
Translation	MLLGWASLLLCAFRLPLAAVGPAATPAQDKAGQPPTAAAAAQPRRRQGEEVQERAEPPGHPHPLAQRRRSKGLVQNIDQLYSGGGKVGYLVYAGGRRFLLDLERDGSVGIAGFVPAGGGTSAPWRHRSHCFYRGTVDGSPRSLAVFDLCGGLDGFFAVKHARYTLKPLLRGPWAEEEKGRVYGDGSARILHVYTREGFSFEALPPRASCETPASTPEAHEHAPAHSNPSGRAALASQLLDQSALSPAGGSGPQTWWRRRRRSISRARQVELLLVADASMARLYGRGLQHYLLTLASIANRLYSHASIENHIRLAVVKVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSCDTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGNCLLDLPRKQILGPEELPGQTYDATQQCNLTFGPEYSVCPGMDVCARLWCAVVRQGQMVCLTKKLPAVEGTPCGKGRICLQGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPRNNGRYCTGKRAIYRSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGVLPADVCKLTCRAKGTGYYVVFSPKVTDGTECRLYSNSVCVRGKCVRTGCDGIIGSKLQYDKCGVCGGDNSSCTKIVGTFNKKSKGYTDVVRIPEGATHIKVRQFKAKDQTRFTAYLALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMGYSATKEILIVQILATDPTKPLDVRYSFFVPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGNRKLAKGCPLSQRPSAFKQCLLKKC

Target ORF information:

RefSeq Version	XM_011529448.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011529448.2

ORF Insert Sequence:

ATGCTGCTCG GGTGGGCGTC CCTGCTGCTG TGCGCGTTCC GCCTGCCCCT GGCCGCGGTC 
GGCCCCGCCG CGACACCTGC CCAGGATAAA GCCGGGCAGC CTCCGACTGC TGCAGCAGCC 
GCCCAGCCCC GCCGGCGGCA GGGGGAGGAG GTGCAGGAGC GAGCCGAGCC TCCCGGCCAC 
CCGCACCCCC TGGCGCAGCG GCGCAGGAGC AAGGGGCTGG TGCAGAACAT CGACCAACTC 
TACTCCGGCG GCGGCAAGGT GGGCTACCTC GTCTACGCGG GCGGCCGGAG GTTCCTCTTG 
GACCTGGAGC GAGATGGTTC GGTGGGCATT GCTGGCTTCG TGCCCGCAGG AGGCGGGACG 
AGTGCGCCCT GGCGCCACCG GAGCCACTGC TTCTATCGGG GCACAGTGGA CGGTAGTCCC 
CGCTCTCTGG CTGTCTTTGA CCTCTGTGGG GGTCTCGACG GCTTCTTCGC GGTCAAGCAC 
GCGCGCTACA CCCTAAAGCC ACTGCTGCGC GGACCCTGGG CGGAGGAAGA AAAGGGGCGC 
GTGTACGGGG ATGGGTCCGC ACGGATCCTG CACGTCTACA CCCGCGAGGG CTTCAGCTTC 
GAGGCCCTGC CGCCGCGCGC CAGCTGCGAA ACCCCCGCGT CCACACCGGA GGCCCACGAG 
CATGCTCCGG CGCACAGCAA CCCGAGCGGA CGCGCAGCAC TGGCCTCGCA GCTCTTGGAC 
CAGTCCGCTC TCTCGCCCGC TGGGGGCTCA GGACCGCAGA CGTGGTGGCG GCGGCGGCGC 
CGCTCCATCT CCCGGGCCCG CCAGGTGGAG CTGCTTCTGG TGGCTGACGC GTCCATGGCG 
CGGTTGTATG GCCGGGGCCT GCAGCATTAC CTGCTGACCC TGGCCTCCAT CGCCAATAGG 
CTGTACAGCC ATGCTAGCAT CGAGAACCAC ATCCGCCTGG CCGTGGTGAA GGTGGTGGTG 
CTAGGCGACA AGGACAAGAG CCTGGAAGTG AGCAAGAACG CTGCCACCAC ACTCAAGAAC 
TTTTGCAAGT GGCAGCACCA ACACAACCAG CTGGGAGATG ACCATGAGGA GCACTACGAT 
GCAGCTATCC TGTTTACTCG GGAGGATTTA TGTGGGCATC ATTCATGTGA CACCCTGGGA 
ATGGCAGACG TTGGGACCAT ATGTTCTCCA GAGCGCAGCT GTGCTGTGAT TGAAGACGAT 
GGCCTCCACG CAGCCTTCAC TGTGGCTCAC GAAATCGGTA ACTGTTTGCT GGACCTACCA 
CGAAAGCAGA TCCTGGGCCC CGAAGAACTC CCAGGACAGA CCTACGATGC CACCCAGCAG 
TGCAACCTGA CATTCGGGCC TGAGTACTCC GTGTGTCCCG GCATGGATGT CTGTGCTCGC 
CTGTGGTGTG CTGTGGTACG CCAGGGCCAG ATGGTCTGTC TGACCAAGAA GCTGCCTGCG 
GTGGAAGGGA CGCCTTGTGG AAAGGGGAGA ATCTGCCTGC AGGGCAAATG TGTGGACAAA 
ACCAAGAAAA AATATTATTC AACGTCAAGC CATGGCAACT GGGGATCTTG GGGATCCTGG 
GGCCAGTGTT CTCGCTCATG TGGAGGAGGA GTGCAGTTTG CCTATCGTCA CTGTAATAAC 
CCTGCTCCCA GAAACAACGG ACGCTACTGC ACAGGGAAGA GGGCCATCTA CCGCTCCTGC 
AGTCTCATGC CCTGCCCACC CAATGGTAAA TCATTTCGTC ATGAACAGTG TGAGGCCAAA 
AATGGCTATC AGTCTGATGC AAAAGGAGTC AAAACTTTTG TGGAATGGGT TCCCAAATAT 
GCAGGTGTCC TGCCAGCGGA TGTGTGCAAG CTGACCTGCA GAGCCAAGGG CACTGGCTAC 
TATGTGGTAT TTTCTCCAAA GGTGACCGAT GGCACTGAAT GTAGGCTGTA CAGTAATTCC 
GTCTGCGTCC GGGGGAAGTG TGTGAGAACT GGCTGTGACG GCATCATTGG CTCAAAGCTG 
CAGTATGACA AGTGCGGAGT ATGTGGAGGA GACAACTCCA GCTGTACAAA GATTGTTGGA 
ACCTTTAATA AGAAAAGTAA GGGTTACACT GACGTGGTGA GGATTCCTGA AGGGGCAACC 
CACATAAAAG TTCGACAGTT CAAAGCCAAA GACCAGACTA GATTCACTGC CTATTTAGCC 
CTGAAAAAGA AAAACGGTGA GTACCTTATC AATGGAAAGT ACATGATCTC CACTTCAGAG 
ACTATCATTG ACATCAATGG AACAGTCATG AACTATAGCG GTTGGAGCCA CAGGGATGAC 
TTCCTGCATG GCATGGGCTA CTCTGCCACG AAGGAAATTC TAATAGTGCA GATTCTTGCA 
ACAGACCCCA CTAAACCATT AGATGTCCGT TATAGCTTTT TTGTTCCCAA GAAGTCCACT 
CCAAAAGTAA ACTCTGTCAC TAGTCATGGC AGCAATAAAG TGGGATCACA CACTTCGCAG 
CCGCAGTGGG TCACGGGCCC ATGGCTCGCC TGCTCTAGGA CCTGTGACAC AGGTTGGCAC 
ACCAGAACGG TGCAGTGCCA GGATGGAAAC CGGAAGTTAG CAAAAGGATG TCCTCTCTCC 
CAAAGGCCTT CTGCGTTTAA GCAATGCTTG TTGAAGAAAT GTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS5 ( XM_024452054.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024307822.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5), transcript variant X2, mRNA.

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CloneID	OHu64714
Clone ID Related Accession (Same CDS sequence)	XM_011529448.2 , XM_024452054.1
Accession Version	XM_024452054.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2625bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 5 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000021.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGCTCG GGTGGGCGTC CCTGCTGCTG TGCGCGTTCC GCCTGCCCCT GGCCGCGGTC 
GGCCCCGCCG CGACACCTGC CCAGGATAAA GCCGGGCAGC CTCCGACTGC TGCAGCAGCC 
GCCCAGCCCC GCCGGCGGCA GGGGGAGGAG GTGCAGGAGC GAGCCGAGCC TCCCGGCCAC 
CCGCACCCCC TGGCGCAGCG GCGCAGGAGC AAGGGGCTGG TGCAGAACAT CGACCAACTC 
TACTCCGGCG GCGGCAAGGT GGGCTACCTC GTCTACGCGG GCGGCCGGAG GTTCCTCTTG 
GACCTGGAGC GAGATGGTTC GGTGGGCATT GCTGGCTTCG TGCCCGCAGG AGGCGGGACG 
AGTGCGCCCT GGCGCCACCG GAGCCACTGC TTCTATCGGG GCACAGTGGA CGGTAGTCCC 
CGCTCTCTGG CTGTCTTTGA CCTCTGTGGG GGTCTCGACG GCTTCTTCGC GGTCAAGCAC 
GCGCGCTACA CCCTAAAGCC ACTGCTGCGC GGACCCTGGG CGGAGGAAGA AAAGGGGCGC 
GTGTACGGGG ATGGGTCCGC ACGGATCCTG CACGTCTACA CCCGCGAGGG CTTCAGCTTC 
GAGGCCCTGC CGCCGCGCGC CAGCTGCGAA ACCCCCGCGT CCACACCGGA GGCCCACGAG 
CATGCTCCGG CGCACAGCAA CCCGAGCGGA CGCGCAGCAC TGGCCTCGCA GCTCTTGGAC 
CAGTCCGCTC TCTCGCCCGC TGGGGGCTCA GGACCGCAGA CGTGGTGGCG GCGGCGGCGC 
CGCTCCATCT CCCGGGCCCG CCAGGTGGAG CTGCTTCTGG TGGCTGACGC GTCCATGGCG 
CGGTTGTATG GCCGGGGCCT GCAGCATTAC CTGCTGACCC TGGCCTCCAT CGCCAATAGG 
CTGTACAGCC ATGCTAGCAT CGAGAACCAC ATCCGCCTGG CCGTGGTGAA GGTGGTGGTG 
CTAGGCGACA AGGACAAGAG CCTGGAAGTG AGCAAGAACG CTGCCACCAC ACTCAAGAAC 
TTTTGCAAGT GGCAGCACCA ACACAACCAG CTGGGAGATG ACCATGAGGA GCACTACGAT 
GCAGCTATCC TGTTTACTCG GGAGGATTTA TGTGGGCATC ATTCATGTGA CACCCTGGGA 
ATGGCAGACG TTGGGACCAT ATGTTCTCCA GAGCGCAGCT GTGCTGTGAT TGAAGACGAT 
GGCCTCCACG CAGCCTTCAC TGTGGCTCAC GAAATCGGTA ACTGTTTGCT GGACCTACCA 
CGAAAGCAGA TCCTGGGCCC CGAAGAACTC CCAGGACAGA CCTACGATGC CACCCAGCAG 
TGCAACCTGA CATTCGGGCC TGAGTACTCC GTGTGTCCCG GCATGGATGT CTGTGCTCGC 
CTGTGGTGTG CTGTGGTACG CCAGGGCCAG ATGGTCTGTC TGACCAAGAA GCTGCCTGCG 
GTGGAAGGGA CGCCTTGTGG AAAGGGGAGA ATCTGCCTGC AGGGCAAATG TGTGGACAAA 
ACCAAGAAAA AATATTATTC AACGTCAAGC CATGGCAACT GGGGATCTTG GGGATCCTGG 
GGCCAGTGTT CTCGCTCATG TGGAGGAGGA GTGCAGTTTG CCTATCGTCA CTGTAATAAC 
CCTGCTCCCA GAAACAACGG ACGCTACTGC ACAGGGAAGA GGGCCATCTA CCGCTCCTGC 
AGTCTCATGC CCTGCCCACC CAATGGTAAA TCATTTCGTC ATGAACAGTG TGAGGCCAAA 
AATGGCTATC AGTCTGATGC AAAAGGAGTC AAAACTTTTG TGGAATGGGT TCCCAAATAT 
GCAGGTGTCC TGCCAGCGGA TGTGTGCAAG CTGACCTGCA GAGCCAAGGG CACTGGCTAC 
TATGTGGTAT TTTCTCCAAA GGTGACCGAT GGCACTGAAT GTAGGCTGTA CAGTAATTCC 
GTCTGCGTCC GGGGGAAGTG TGTGAGAACT GGCTGTGACG GCATCATTGG CTCAAAGCTG 
CAGTATGACA AGTGCGGAGT ATGTGGAGGA GACAACTCCA GCTGTACAAA GATTGTTGGA 
ACCTTTAATA AGAAAAGTAA GGGTTACACT GACGTGGTGA GGATTCCTGA AGGGGCAACC 
CACATAAAAG TTCGACAGTT CAAAGCCAAA GACCAGACTA GATTCACTGC CTATTTAGCC 
CTGAAAAAGA AAAACGGTGA GTACCTTATC AATGGAAAGT ACATGATCTC CACTTCAGAG 
ACTATCATTG ACATCAATGG AACAGTCATG AACTATAGCG GTTGGAGCCA CAGGGATGAC 
TTCCTGCATG GCATGGGCTA CTCTGCCACG AAGGAAATTC TAATAGTGCA GATTCTTGCA 
ACAGACCCCA CTAAACCATT AGATGTCCGT TATAGCTTTT TTGTTCCCAA GAAGTCCACT 
CCAAAAGTAA ACTCTGTCAC TAGTCATGGC AGCAATAAAG TGGGATCACA CACTTCGCAG 
CCGCAGTGGG TCACGGGCCC ATGGCTCGCC TGCTCTAGGA CCTGTGACAC AGGTTGGCAC 
ACCAGAACGG TGCAGTGCCA GGATGGAAAC CGGAAGTTAG CAAAAGGATG TCCTCTCTCC 
CAAAGGCCTT CTGCGTTTAA GCAATGCTTG TTGAAGAAAT GTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024307822.1
CDS	1059..3683
Translation	MLLGWASLLLCAFRLPLAAVGPAATPAQDKAGQPPTAAAAAQPRRRQGEEVQERAEPPGHPHPLAQRRRSKGLVQNIDQLYSGGGKVGYLVYAGGRRFLLDLERDGSVGIAGFVPAGGGTSAPWRHRSHCFYRGTVDGSPRSLAVFDLCGGLDGFFAVKHARYTLKPLLRGPWAEEEKGRVYGDGSARILHVYTREGFSFEALPPRASCETPASTPEAHEHAPAHSNPSGRAALASQLLDQSALSPAGGSGPQTWWRRRRRSISRARQVELLLVADASMARLYGRGLQHYLLTLASIANRLYSHASIENHIRLAVVKVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSCDTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGNCLLDLPRKQILGPEELPGQTYDATQQCNLTFGPEYSVCPGMDVCARLWCAVVRQGQMVCLTKKLPAVEGTPCGKGRICLQGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPRNNGRYCTGKRAIYRSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGVLPADVCKLTCRAKGTGYYVVFSPKVTDGTECRLYSNSVCVRGKCVRTGCDGIIGSKLQYDKCGVCGGDNSSCTKIVGTFNKKSKGYTDVVRIPEGATHIKVRQFKAKDQTRFTAYLALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMGYSATKEILIVQILATDPTKPLDVRYSFFVPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGNRKLAKGCPLSQRPSAFKQCLLKKC

Target ORF information:

RefSeq Version	XM_024452054.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024452054.1

ORF Insert Sequence:

ATGCTGCTCG GGTGGGCGTC CCTGCTGCTG TGCGCGTTCC GCCTGCCCCT GGCCGCGGTC 
GGCCCCGCCG CGACACCTGC CCAGGATAAA GCCGGGCAGC CTCCGACTGC TGCAGCAGCC 
GCCCAGCCCC GCCGGCGGCA GGGGGAGGAG GTGCAGGAGC GAGCCGAGCC TCCCGGCCAC 
CCGCACCCCC TGGCGCAGCG GCGCAGGAGC AAGGGGCTGG TGCAGAACAT CGACCAACTC 
TACTCCGGCG GCGGCAAGGT GGGCTACCTC GTCTACGCGG GCGGCCGGAG GTTCCTCTTG 
GACCTGGAGC GAGATGGTTC GGTGGGCATT GCTGGCTTCG TGCCCGCAGG AGGCGGGACG 
AGTGCGCCCT GGCGCCACCG GAGCCACTGC TTCTATCGGG GCACAGTGGA CGGTAGTCCC 
CGCTCTCTGG CTGTCTTTGA CCTCTGTGGG GGTCTCGACG GCTTCTTCGC GGTCAAGCAC 
GCGCGCTACA CCCTAAAGCC ACTGCTGCGC GGACCCTGGG CGGAGGAAGA AAAGGGGCGC 
GTGTACGGGG ATGGGTCCGC ACGGATCCTG CACGTCTACA CCCGCGAGGG CTTCAGCTTC 
GAGGCCCTGC CGCCGCGCGC CAGCTGCGAA ACCCCCGCGT CCACACCGGA GGCCCACGAG 
CATGCTCCGG CGCACAGCAA CCCGAGCGGA CGCGCAGCAC TGGCCTCGCA GCTCTTGGAC 
CAGTCCGCTC TCTCGCCCGC TGGGGGCTCA GGACCGCAGA CGTGGTGGCG GCGGCGGCGC 
CGCTCCATCT CCCGGGCCCG CCAGGTGGAG CTGCTTCTGG TGGCTGACGC GTCCATGGCG 
CGGTTGTATG GCCGGGGCCT GCAGCATTAC CTGCTGACCC TGGCCTCCAT CGCCAATAGG 
CTGTACAGCC ATGCTAGCAT CGAGAACCAC ATCCGCCTGG CCGTGGTGAA GGTGGTGGTG 
CTAGGCGACA AGGACAAGAG CCTGGAAGTG AGCAAGAACG CTGCCACCAC ACTCAAGAAC 
TTTTGCAAGT GGCAGCACCA ACACAACCAG CTGGGAGATG ACCATGAGGA GCACTACGAT 
GCAGCTATCC TGTTTACTCG GGAGGATTTA TGTGGGCATC ATTCATGTGA CACCCTGGGA 
ATGGCAGACG TTGGGACCAT ATGTTCTCCA GAGCGCAGCT GTGCTGTGAT TGAAGACGAT 
GGCCTCCACG CAGCCTTCAC TGTGGCTCAC GAAATCGGTA ACTGTTTGCT GGACCTACCA 
CGAAAGCAGA TCCTGGGCCC CGAAGAACTC CCAGGACAGA CCTACGATGC CACCCAGCAG 
TGCAACCTGA CATTCGGGCC TGAGTACTCC GTGTGTCCCG GCATGGATGT CTGTGCTCGC 
CTGTGGTGTG CTGTGGTACG CCAGGGCCAG ATGGTCTGTC TGACCAAGAA GCTGCCTGCG 
GTGGAAGGGA CGCCTTGTGG AAAGGGGAGA ATCTGCCTGC AGGGCAAATG TGTGGACAAA 
ACCAAGAAAA AATATTATTC AACGTCAAGC CATGGCAACT GGGGATCTTG GGGATCCTGG 
GGCCAGTGTT CTCGCTCATG TGGAGGAGGA GTGCAGTTTG CCTATCGTCA CTGTAATAAC 
CCTGCTCCCA GAAACAACGG ACGCTACTGC ACAGGGAAGA GGGCCATCTA CCGCTCCTGC 
AGTCTCATGC CCTGCCCACC CAATGGTAAA TCATTTCGTC ATGAACAGTG TGAGGCCAAA 
AATGGCTATC AGTCTGATGC AAAAGGAGTC AAAACTTTTG TGGAATGGGT TCCCAAATAT 
GCAGGTGTCC TGCCAGCGGA TGTGTGCAAG CTGACCTGCA GAGCCAAGGG CACTGGCTAC 
TATGTGGTAT TTTCTCCAAA GGTGACCGAT GGCACTGAAT GTAGGCTGTA CAGTAATTCC 
GTCTGCGTCC GGGGGAAGTG TGTGAGAACT GGCTGTGACG GCATCATTGG CTCAAAGCTG 
CAGTATGACA AGTGCGGAGT ATGTGGAGGA GACAACTCCA GCTGTACAAA GATTGTTGGA 
ACCTTTAATA AGAAAAGTAA GGGTTACACT GACGTGGTGA GGATTCCTGA AGGGGCAACC 
CACATAAAAG TTCGACAGTT CAAAGCCAAA GACCAGACTA GATTCACTGC CTATTTAGCC 
CTGAAAAAGA AAAACGGTGA GTACCTTATC AATGGAAAGT ACATGATCTC CACTTCAGAG 
ACTATCATTG ACATCAATGG AACAGTCATG AACTATAGCG GTTGGAGCCA CAGGGATGAC 
TTCCTGCATG GCATGGGCTA CTCTGCCACG AAGGAAATTC TAATAGTGCA GATTCTTGCA 
ACAGACCCCA CTAAACCATT AGATGTCCGT TATAGCTTTT TTGTTCCCAA GAAGTCCACT 
CCAAAAGTAA ACTCTGTCAC TAGTCATGGC AGCAATAAAG TGGGATCACA CACTTCGCAG 
CCGCAGTGGG TCACGGGCCC ATGGCTCGCC TGCTCTAGGA CCTGTGACAC AGGTTGGCAC 
ACCAGAACGG TGCAGTGCCA GGATGGAAAC CGGAAGTTAG CAAAAGGATG TCCTCTCTCC 
CAAAGGCCTT CTGCGTTTAA GCAATGCTTG TTGAAGAAAT GTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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ADAMTS5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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