RAPGEF4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RAPGEF4
Entrez Gene ID	11069
Full Name	Rap guanine nucleotide exchange factor 4
Synonyms	CAMP-GEFII,CGEF2,EPAC,EPAC 2,EPAC2,Nbla00496
General protein information	Preferred Names Rap guanine nucleotide exchange factor 4 Names rap guanine nucleotide exchange factor 4 RAP guanine-nucleotide-exchange factor (GEF) 4 Rap guanine nucleotide exchange factor (GEF) 4 cAMP-regulated guanine nucleotide exchange factor II exchange factor directly activated by cAMP 2 exchange protein directly activated by cAMP 2 putative protein product of Nbla00496
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q31.1
Disorder MIM:	606058

mRNA and Protein(s)

mRNA	Protein	Name
XM_011510505.2	XP_011508807.1	rap guanine nucleotide exchange factor 4 isoform X3
XM_005246246.3	XP_005246303.1	rap guanine nucleotide exchange factor 4 isoform X1
NM_001375868.1	NP_001362797.1	rap guanine nucleotide exchange factor 4 isoform j
NM_001375864.1	NP_001362793.1	rap guanine nucleotide exchange factor 4 isoform f
NM_001375869.1	NP_001362798.1	rap guanine nucleotide exchange factor 4 isoform k
NM_001375865.1	NP_001362794.1	rap guanine nucleotide exchange factor 4 isoform g
XM_017003197.1	XP_016858686.1	rap guanine nucleotide exchange factor 4 isoform X4
NM_007023.3	NP_008954.2	rap guanine nucleotide exchange factor 4 isoform a
XM_005246246.2	XP_005246303.1	rap guanine nucleotide exchange factor 4 isoform X1
NM_001282901.1	NP_001269830.1	rap guanine nucleotide exchange factor 4 isoform e
NM_001375872.1	NP_001362801.1	rap guanine nucleotide exchange factor 4 isoform n
NM_001282900.2	NP_001269829.1	rap guanine nucleotide exchange factor 4 isoform d
NM_001375874.1	NP_001362803.1	rap guanine nucleotide exchange factor 4 isoform p
NM_001375873.1	NP_001362802.1	rap guanine nucleotide exchange factor 4 isoform o
XM_017003196.1	XP_016858685.1	rap guanine nucleotide exchange factor 4 isoform X2
NM_001282900.1	NP_001269829.1	rap guanine nucleotide exchange factor 4 isoform d
NM_001100397.1	NP_001093867.1	rap guanine nucleotide exchange factor 4 isoform b
NM_007023.4	NP_008954.2	rap guanine nucleotide exchange factor 4 isoform a
NM_001100397.2	NP_001093867.1	rap guanine nucleotide exchange factor 4 isoform b
NM_001375870.1	NP_001362799.1	rap guanine nucleotide exchange factor 4 isoform l
NM_001375871.1	NP_001362800.1	rap guanine nucleotide exchange factor 4 isoform m
NM_001375866.1	NP_001362795.1	rap guanine nucleotide exchange factor 4 isoform h
NM_001375867.1	NP_001362796.1	rap guanine nucleotide exchange factor 4 isoform i
NM_001282901.2	NP_001269830.1	rap guanine nucleotide exchange factor 4 isoform e
XM_017003196.2	XP_016858685.1	rap guanine nucleotide exchange factor 4 isoform X2
XM_011510505.3	XP_011508807.1	rap guanine nucleotide exchange factor 4 isoform X3
XM_006712205.3	XP_006712268.1	rap guanine nucleotide exchange factor 4 isoform X5
NM_001282899.1	NP_001269828.1	rap guanine nucleotide exchange factor 4 isoform c
NM_001375875.1	NP_001362804.1	rap guanine nucleotide exchange factor 4 isoform q
NM_001282899.2	NP_001269828.1	rap guanine nucleotide exchange factor 4 isoform c
NM_001375876.1	NP_001362805.1	rap guanine nucleotide exchange factor 4 isoform r

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Rapgef4	XP_006234430.1
Xenopus tropicalis (tropical clawed frog)	rapgef4	XP_002934663.2
Pan troglodytes (chimpanzee)	RAPGEF4	XP_003309469.1
Canis lupus familiaris (dog)	RAPGEF4	XP_005640372.1
Mus musculus (house mouse)	Rapgef4	NP_001191094.1
Homo sapiens (human)	RAPGEF4	NP_008954.2
	RAPGEF4	XP_001086678.2
Bos taurus (cattle)	RAPGEF4	NP_001179831.1
Gallus gallus (chicken)	RAPGEF4	XP_426579.3
Danio rerio (zebrafish)	rapgef4	XP_687578.4
Drosophila melanogaster (fruit fly)	Epac	NP_001097202.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007307	XP_308514.4
Caenorhabditis elegans (roundworm)	epac-1	NP_499256.2

Gene Ontology
Bibliography

Related articles in PubMed

Epac2-Rap1 Signaling Regulates Reactive Oxygen Species Production and Susceptibility to Cardiac Arrhythmias.
Yang Z, Kirton HM, Al-Owais M, Thireau J, Richard S, Peers C, Steele DS
Antioxidants & redox signaling27(3)117-132(2017 Jul)

The role of Epac in the heart.
Fujita T, Umemura M, Yokoyama U, Okumura S, Ishikawa Y
Cellular and molecular life sciences : CMLS74(4)591-606(2017 Feb)

Anxiety and depression with neurogenesis defects in exchange protein directly activated by cAMP 2-deficient mice are ameliorated by a selective serotonin reuptake inhibitor, Prozac.
Zhou L, Ma SL, Yeung PK, Wong YH, Tsim KW, So KF, Lam LC, Chung SK
Translational psychiatry6(9)e881(2016 09)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This review focus is on the function of Epac in the heart. Accumulating evidence has revealed that both Epac1 and Epac2 play important roles in the structure and function of the heart under physiological and pathological conditions. [review]
Title: The role of Epac in the heart.

rs17746510, one of the three single-nucleotide polymorphisms (SNPs) in RAPGEF4 associated with cognitive decline in Chinese Alzheimer's disease (AD) patients, was significantly correlated with apathy and mood disturbance
Title: Anxiety and depression with neurogenesis defects in exchange protein directly activated by cAMP 2-deficient mice are ameliorated by a selective serotonin reuptake inhibitor, Prozac.

Data show that Epac2 is activated by cAMP and changes its structure. It is involved in cAMP-mediated signal transduction through activation of the Ras-like small GTPase and is expressed mainly in brain, neuroendocrine and endocrine tissues. [review]
Title: Structure and functional roles of Epac2 (Rapgef4).

Identified a conserved nuclear pore localisation signal (NPLS; amino acids 764-838 of EPAC1) in the catalytic domains of the cAMP-sensors, EPAC1 and EPAC2A. EPAC1 and EPAC2, display distinct subcellular distributions.
Title: The cAMP sensors, EPAC1 and EPAC2, display distinct subcellular distributions despite sharing a common nuclear pore localisation signal.

CALR regulated by EPAC2 in endometrial glandular epithelial cells is critical for the expression of LIF and PTGS2-mediated production of PGE2 through cAMP signaling.
Title: EPAC2-mediated calreticulin regulates LIF and COX2 expression in human endometrial glandular cells.

The following RAPGEF4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RAPGEF4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu109022	NM_001375875.1 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 17, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu109025	NM_001375876.1 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 18, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu20982	XM_006712205.3 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu35775	XM_005246246.3 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu64677	XM_011510505.3 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu109023	NM_001375868.1 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 10, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu109024	NM_001375872.1 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 14, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu109027	NM_001375870.1 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 12, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu109028	NM_001375874.1 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 16, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu109029	NM_001375869.1 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 11, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu109030	NM_001375871.1 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 13, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu109032	NM_001375867.1 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu109033	NM_001375873.1 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 15, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu17215	NM_001100397.2 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu20982	NM_001282900.2 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu21563	NM_001282901.2 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu21628	NM_001282899.2 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu35775	NM_001375866.1 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu88944	XM_017003196.2 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu88945	XM_017003197.1 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu109026	NM_001375864.1 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OHu109031	NM_001375865.1 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OHu17245	NM_007023.4 Latest version!	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$69.30 $99.00
View Old Accession Versions >>
OHu35775	XM_005246246.2	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu20982	NM_001282900.1	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu17245	NM_007023.3	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$69.30 $99.00
OHu17215	NM_001100397.1	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu21563	NM_001282901.1	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu88944	XM_017003196.1	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu64677	XM_011510505.2	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu21628	NM_001282899.1	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RAPGEF4 ( NM_001375875.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001362804.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 17, mRNA.

Price & Availability↑

CloneID	OHu109022
Clone ID Related Accession (Same CDS sequence)	NM_001375875.1
Accession Version	NM_001375875.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1029bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform q
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018712.5, AC009484.3 and AC104086.6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.285551.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCGGTGTG GAATTTAAAA 
TCCTGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001362804.1
CDS	140..1168
Translation	MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPVWNLKSW

Target ORF information:

RefSeq Version	NM_001375875.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 17, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001375875.1

ORF Insert Sequence:

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCGGTGTG GAATTTAAAA 
TCCTGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001375876.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001362805.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 18, mRNA.

Price & Availability↑

CloneID	OHu109025
Clone ID Related Accession (Same CDS sequence)	NM_001375876.1
Accession Version	NM_001375876.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 975bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform r
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018712.5, AC009484.3 and AC104086.6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.24796.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACGTC 
CCTTCAGAGA AGATCCTCAG AGCTGGAAAA ATTTTACGAA ATGCCATTCT CTCTCGAGCA 
CCTCACATGA TAAGAGATAG AAAATACCAC CTAAAGACAT ACAGACAATG CTGTGTGGGA 
ACTGAACTGG TGGACTGGAT GATGCAGCAG ACACCATGTG TTCACTCCCG GACTCAAGCT 
GTTGGCATGT GGCAAGTCCT GTTAGAAGAT GGTGTTCTCA ACCACGTGGA CCAGGAGCAC 
CATTTCCAAG ACAAATATTT ATTCTATCGA TTTCTGGATG ATGAGCACGA GGATGCCCCT 
TTGCCTACTG AGGAGGAGAA GAAGGAGTGT GATGAGGAGC TCCAGGACAC CATGCTGCTG 
CTGTCACAGA TGGGCCCCGA CGCCCACATG AGGATGATCC TTCGCAAACC GGTGTGGAAT 
TTAAAATCCT GGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001362805.1
CDS	140..1114
Translation	MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPVWNLKSW

Target ORF information:

RefSeq Version	NM_001375876.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 18, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001375876.1

ORF Insert Sequence:

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACGTC 
CCTTCAGAGA AGATCCTCAG AGCTGGAAAA ATTTTACGAA ATGCCATTCT CTCTCGAGCA 
CCTCACATGA TAAGAGATAG AAAATACCAC CTAAAGACAT ACAGACAATG CTGTGTGGGA 
ACTGAACTGG TGGACTGGAT GATGCAGCAG ACACCATGTG TTCACTCCCG GACTCAAGCT 
GTTGGCATGT GGCAAGTCCT GTTAGAAGAT GGTGTTCTCA ACCACGTGGA CCAGGAGCAC 
CATTTCCAAG ACAAATATTT ATTCTATCGA TTTCTGGATG ATGAGCACGA GGATGCCCCT 
TTGCCTACTG AGGAGGAGAA GAAGGAGTGT GATGAGGAGC TCCAGGACAC CATGCTGCTG 
CTGTCACAGA TGGGCCCCGA CGCCCACATG AGGATGATCC TTCGCAAACC GGTGTGGAAT 
TTAAAATCCT GGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001100397.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093867.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu17215
Clone ID Related Accession (Same CDS sequence)	NM_001100397.1 , NM_001100397.2
Accession Version	NM_001100397.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2604bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-22
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC040183.2, BC024004.2, AB027471.1 and BQ184791.1. Transcript Variant: This variant (2) differs in its 5' UTR, lacks several exons in the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC040183.2, SRR1660807.143230.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTCTACA AGAAATATCG ACAGTATATG GCAGGACTTC TGGCTCCTCC TTATGGTGTT 
ATGGAAACGG GCTCTAACAA TGACAGGATT CCTGACAAGG AGAACACACC TCTCATTGAA 
CCTCACGTTC CTCTTCGTCC TGCTAACACC ATTACCAAGG TCCCTTCAGA GAAGATCCTC 
AGAGCTGGAA AAATTTTACG AAATGCCATT CTCTCTCGAG CACCTCACAT GATAAGAGAT 
AGAAAATACC ACCTAAAGAC ATACAGACAA TGCTGTGTGG GAACTGAACT GGTGGACTGG 
ATGATGCAGC AGACACCATG TGTTCACTCC CGGACTCAAG CTGTTGGCAT GTGGCAAGTC 
CTGTTAGAAG ATGGTGTTCT CAACCACGTG GACCAGGAGC ACCATTTCCA AGACAAATAT 
TTATTCTATC GATTTCTGGA TGATGAGCAC GAGGATGCCC CTTTGCCTAC TGAGGAGGAG 
AAGAAGGAGT GTGATGAGGA GCTCCAGGAC ACCATGCTGC TGCTGTCACA GATGGGCCCC 
GACGCCCACA TGAGGATGAT CCTTCGCAAA CCACCTGGCC AGAGGACTGT GGATGACCTA 
GAGATTATCT ATGAGGAGCT TCTTCATATT AAAGCCTTAT CCCATCTTTC TACCACAGTG 
AAACGAGAGT TAGCAGGTGT TCTCATTTTT GAGTCTCACG CCAAAGGAGG GACTGTGTTG 
TTTAACCAGG GGGAAGAAGG TACCTCCTGG TACATTATTC TAAAAGGATC AGTGAATGTA 
GTCATTTACG GCAAGGGTGT GGTCTGCACC CTGCATGAAG GAGATGACTT CGGCAAGTTA 
GCACTAGTGA ATGATGCCCC ACGAGCTGCC TCTATCGTCT TACGAGAAGA TAACTGCCAT 
TTCTTAAGAG TAGACAAGGA GGATTTCAAC CGGATCCTAA GGGACGTGGA GGCGAATACA 
GTCAGACTTA AAGAACATGA CCAAGATGTC TTGGTGCTGG AGAAGGTCCC AGCAGGGAAC 
AGAGCTTCTA ATCAAGGAAA CTCACAGCCT CAGCAAAAGT ATACTGTGAT GTCAGGAACA 
CCTGAAAAAA TTTTAGAGCA TTTTCTAGAA ACAATACGCC TTGAGGCAAC TTTAAATGAA 
GCAACAGATT CTGTTTTAAA TGACTTTATT ATGATGCACT GTGTTTTTAT GCCAAATACC 
CAGCTTTGCC CGGCACTGGT GGCCCACTAC CACGCACAGC CTTCACAAGG TACAGAACAG 
GAGAAAATGG ATTATGCCCT CAACAATAAG AGGCGAGTCA TCCGCCTGGT TCTACAGTGG 
GCTGCCATGT ATGGAGACCT CCTGCAAGAG GATGACGTGT CTATGGCCTT CCTGGAGGAG 
TTTTATGTAT CTGTATCAGA TGATGCCCGG ATGATTGCTG CCCTCAAGGA GCAACTGCCA 
GAGTTGGAGA AGATTGTCAA GCAAATCTCA GAAGATGCAA AGGCACCACA AAAGAAGCAC 
AAGGTTCTTT TGCAACAGTT CAATACGGGC GATGAGAGAG CCCAGAAGCG CCAGCCTATC 
CGCGGCTCTG ATGAAGTTCT GTTTAAGGTC TATTGCATGG ACCACACCTA CACAACCATT 
CGGGTGCCAG TGGCCACTTC GGTGAAGGAA GTCATCAGTG CAGTTGCCGA CAAGCTGGGC 
TCCGGGGAGG GCCTGATCAT AGTCAAGATG AGTTCCGGAG GAGAAAAGGT GGTGCTCAAA 
CCTAATGATG TTTCAGTATT TACGACGCTC ACCATTAATG GACGCCTGTT TGCTTGCCCG 
CGAGAGCAAT TCGATTCACT GACTCCCTTA CCAGAACAGG AAGGCCCAAC TGTTGGAACA 
GTGGGAACTT TTGAACTGAT GAGCTCCAAA GATTTAGCAT ACCAGATGAC AATTTATGAT 
TGGGAACTCT TCAACTGCGT GCATGAGCTG GAGCTAATCT ATCACACATT TGGAAGGCAT 
AATTTTAAAA AGACCACAGC AAACTTGGAT TTGTTCCTGA GGAGATTTAA TGAAATTCAG 
TTTTGGGTCG TCACTGAGAT CTGCCTTTGT TCTCAGCTCA GCAAGCGTGT TCAGCTATTA 
AAAAAATTTA TTAAGATAGC AGCCCACTGT AAGGAGTATA AAAATCTGAA TTCCTTTTTT 
GCCATCGTCA TGGGACTAAG TAACGTTGCT GTGAGCCGCT TGGCACTAAC GTGGGAGAAA 
CTGCCAAGCA AGTTCAAGAA GTTCTATGCG GAGTTTGAAA GTTTAATGGA CCCTTCAAGG 
AACCACAGGG CCTACAGGCT GACAGTAGCT AAGCTGGAAC CTCCTCTCAT CCCCTTCATG 
CCTTTGCTCA TTAAAGATAT GACATTTACT CATGAGGGGA ACAAGACGTT CATTGACAAT 
CTAGTAAACT TTGAAAAAAT GCGCATGATT GCAAATACGG CCAGAACAGT GAGATACTAC 
AGGAGCCAAC CCTTCAATCC TGATGCAGCT CAAGCTAATA AGAACCATCA GGATGTCCGG 
AGTTATGTAC GGCAATTAAA TGTGATTGAC AACCAGAGAA CTTTATCACA GATGTCACAC 
AGATTAGAGC CTCGTCGACC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093867.1
CDS	379..2982
Translation	MLYKKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	NM_001100397.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100397.1

ORF Insert Sequence:

ATGCTCTACA AGAAATATCG ACAGTATATG GCAGGACTTC TGGCTCCTCC TTATGGTGTT 
ATGGAAACGG GCTCTAACAA TGACAGGATT CCTGACAAGG AGAACACACC TCTCATTGAA 
CCTCACGTTC CTCTTCGTCC TGCTAACACC ATTACCAAGG TCCCTTCAGA GAAGATCCTC 
AGAGCTGGAA AAATTTTACG AAATGCCATT CTCTCTCGAG CACCTCACAT GATAAGAGAT 
AGAAAATACC ACCTAAAGAC ATACAGACAA TGCTGTGTGG GAACTGAACT GGTGGACTGG 
ATGATGCAGC AGACACCATG TGTTCACTCC CGGACTCAAG CTGTTGGCAT GTGGCAAGTC 
CTGTTAGAAG ATGGTGTTCT CAACCACGTG GACCAGGAGC ACCATTTCCA AGACAAATAT 
TTATTCTATC GATTTCTGGA TGATGAGCAC GAGGATGCCC CTTTGCCTAC TGAGGAGGAG 
AAGAAGGAGT GTGATGAGGA GCTCCAGGAC ACCATGCTGC TGCTGTCACA GATGGGCCCC 
GACGCCCACA TGAGGATGAT CCTTCGCAAA CCACCTGGCC AGAGGACTGT GGATGACCTA 
GAGATTATCT ATGAGGAGCT TCTTCATATT AAAGCCTTAT CCCATCTTTC TACCACAGTG 
AAACGAGAGT TAGCAGGTGT TCTCATTTTT GAGTCTCACG CCAAAGGAGG GACTGTGTTG 
TTTAACCAGG GGGAAGAAGG TACCTCCTGG TACATTATTC TAAAAGGATC AGTGAATGTA 
GTCATTTACG GCAAGGGTGT GGTCTGCACC CTGCATGAAG GAGATGACTT CGGCAAGTTA 
GCACTAGTGA ATGATGCCCC ACGAGCTGCC TCTATCGTCT TACGAGAAGA TAACTGCCAT 
TTCTTAAGAG TAGACAAGGA GGATTTCAAC CGGATCCTAA GGGACGTGGA GGCGAATACA 
GTCAGACTTA AAGAACATGA CCAAGATGTC TTGGTGCTGG AGAAGGTCCC AGCAGGGAAC 
AGAGCTTCTA ATCAAGGAAA CTCACAGCCT CAGCAAAAGT ATACTGTGAT GTCAGGAACA 
CCTGAAAAAA TTTTAGAGCA TTTTCTAGAA ACAATACGCC TTGAGGCAAC TTTAAATGAA 
GCAACAGATT CTGTTTTAAA TGACTTTATT ATGATGCACT GTGTTTTTAT GCCAAATACC 
CAGCTTTGCC CGGCACTGGT GGCCCACTAC CACGCACAGC CTTCACAAGG TACAGAACAG 
GAGAAAATGG ATTATGCCCT CAACAATAAG AGGCGAGTCA TCCGCCTGGT TCTACAGTGG 
GCTGCCATGT ATGGAGACCT CCTGCAAGAG GATGACGTGT CTATGGCCTT CCTGGAGGAG 
TTTTATGTAT CTGTATCAGA TGATGCCCGG ATGATTGCTG CCCTCAAGGA GCAACTGCCA 
GAGTTGGAGA AGATTGTCAA GCAAATCTCA GAAGATGCAA AGGCACCACA AAAGAAGCAC 
AAGGTTCTTT TGCAACAGTT CAATACGGGC GATGAGAGAG CCCAGAAGCG CCAGCCTATC 
CGCGGCTCTG ATGAAGTTCT GTTTAAGGTC TATTGCATGG ACCACACCTA CACAACCATT 
CGGGTGCCAG TGGCCACTTC GGTGAAGGAA GTCATCAGTG CAGTTGCCGA CAAGCTGGGC 
TCCGGGGAGG GCCTGATCAT AGTCAAGATG AGTTCCGGAG GAGAAAAGGT GGTGCTCAAA 
CCTAATGATG TTTCAGTATT TACGACGCTC ACCATTAATG GACGCCTGTT TGCTTGCCCG 
CGAGAGCAAT TCGATTCACT GACTCCCTTA CCAGAACAGG AAGGCCCAAC TGTTGGAACA 
GTGGGAACTT TTGAACTGAT GAGCTCCAAA GATTTAGCAT ACCAGATGAC AATTTATGAT 
TGGGAACTCT TCAACTGCGT GCATGAGCTG GAGCTAATCT ATCACACATT TGGAAGGCAT 
AATTTTAAAA AGACCACAGC AAACTTGGAT TTGTTCCTGA GGAGATTTAA TGAAATTCAG 
TTTTGGGTCG TCACTGAGAT CTGCCTTTGT TCTCAGCTCA GCAAGCGTGT TCAGCTATTA 
AAAAAATTTA TTAAGATAGC AGCCCACTGT AAGGAGTATA AAAATCTGAA TTCCTTTTTT 
GCCATCGTCA TGGGACTAAG TAACGTTGCT GTGAGCCGCT TGGCACTAAC GTGGGAGAAA 
CTGCCAAGCA AGTTCAAGAA GTTCTATGCG GAGTTTGAAA GTTTAATGGA CCCTTCAAGG 
AACCACAGGG CCTACAGGCT GACAGTAGCT AAGCTGGAAC CTCCTCTCAT CCCCTTCATG 
CCTTTGCTCA TTAAAGATAT GACATTTACT CATGAGGGGA ACAAGACGTT CATTGACAAT 
CTAGTAAACT TTGAAAAAAT GCGCATGATT GCAAATACGG CCAGAACAGT GAGATACTAC 
AGGAGCCAAC CCTTCAATCC TGATGCAGCT CAAGCTAATA AGAACCATCA GGATGTCCGG 
AGTTATGTAC GGCAATTAAA TGTGATTGAC AACCAGAGAA CTTTATCACA GATGTCACAC 
AGATTAGAGC CTCGTCGACC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001282900.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269829.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu20982
Clone ID Related Accession (Same CDS sequence)	NM_001282900.2 , NM_001282900.1 , XM_006712205.3
Accession Version	NM_001282900.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2523bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-22
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform d
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC335305.1, AK296340.1, U78516.1 and BQ184791.1. On Sep 20, 2013 this sequence version replaced XM_005246249.1. Transcript Variant: This variant (4) differs in its 5' UTR, lacks several exons in the 5' coding region, initiates translation at a downstream in-frame start codon, and lacks an additional in-frame exon in the 5' coding region, compared to variant 1. The encoded isoform (d) is shorter at the N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.207914.1, SRR1803617.114623.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2145544 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGGAC TTCTGGCTCC TCCTTATGGT GTTATGGAAA CGGGCTCTAA CAATGACAGG 
ATTCCTGACA AGGAGAACGT CCCTTCAGAG AAGATCCTCA GAGCTGGAAA AATTTTACGA 
AATGCCATTC TCTCTCGAGC ACCTCACATG ATAAGAGATA GAAAATACCA CCTAAAGACA 
TACAGACAAT GCTGTGTGGG AACTGAACTG GTGGACTGGA TGATGCAGCA GACACCATGT 
GTTCACTCCC GGACTCAAGC TGTTGGCATG TGGCAAGTCC TGTTAGAAGA TGGTGTTCTC 
AACCACGTGG ACCAGGAGCA CCATTTCCAA GACAAATATT TATTCTATCG ATTTCTGGAT 
GATGAGCACG AGGATGCCCC TTTGCCTACT GAGGAGGAGA AGAAGGAGTG TGATGAGGAG 
CTCCAGGACA CCATGCTGCT GCTGTCACAG ATGGGCCCCG ACGCCCACAT GAGGATGATC 
CTTCGCAAAC CACCTGGCCA GAGGACTGTG GATGACCTAG AGATTATCTA TGAGGAGCTT 
CTTCATATTA AAGCCTTATC CCATCTTTCT ACCACAGTGA AACGAGAGTT AGCAGGTGTT 
CTCATTTTTG AGTCTCACGC CAAAGGAGGG ACTGTGTTGT TTAACCAGGG GGAAGAAGGT 
ACCTCCTGGT ACATTATTCT AAAAGGATCA GTGAATGTAG TCATTTACGG CAAGGGTGTG 
GTCTGCACCC TGCATGAAGG AGATGACTTC GGCAAGTTAG CACTAGTGAA TGATGCCCCA 
CGAGCTGCCT CTATCGTCTT ACGAGAAGAT AACTGCCATT TCTTAAGAGT AGACAAGGAG 
GATTTCAACC GGATCCTAAG GGACGTGGAG GCGAATACAG TCAGACTTAA AGAACATGAC 
CAAGATGTCT TGGTGCTGGA GAAGGTCCCA GCAGGGAACA GAGCTTCTAA TCAAGGAAAC 
TCACAGCCTC AGCAAAAGTA TACTGTGATG TCAGGAACAC CTGAAAAAAT TTTAGAGCAT 
TTTCTAGAAA CAATACGCCT TGAGGCAACT TTAAATGAAG CAACAGATTC TGTTTTAAAT 
GACTTTATTA TGATGCACTG TGTTTTTATG CCAAATACCC AGCTTTGCCC GGCACTGGTG 
GCCCACTACC ACGCACAGCC TTCACAAGGT ACAGAACAGG AGAAAATGGA TTATGCCCTC 
AACAATAAGA GGCGAGTCAT CCGCCTGGTT CTACAGTGGG CTGCCATGTA TGGAGACCTC 
CTGCAAGAGG ATGACGTGTC TATGGCCTTC CTGGAGGAGT TTTATGTATC TGTATCAGAT 
GATGCCCGGA TGATTGCTGC CCTCAAGGAG CAACTGCCAG AGTTGGAGAA GATTGTCAAG 
CAAATCTCAG AAGATGCAAA GGCACCACAA AAGAAGCACA AGGTTCTTTT GCAACAGTTC 
AATACGGGCG ATGAGAGAGC CCAGAAGCGC CAGCCTATCC GCGGCTCTGA TGAAGTTCTG 
TTTAAGGTCT ATTGCATGGA CCACACCTAC ACAACCATTC GGGTGCCAGT GGCCACTTCG 
GTGAAGGAAG TCATCAGTGC AGTTGCCGAC AAGCTGGGCT CCGGGGAGGG CCTGATCATA 
GTCAAGATGA GTTCCGGAGG AGAAAAGGTG GTGCTCAAAC CTAATGATGT TTCAGTATTT 
ACGACGCTCA CCATTAATGG ACGCCTGTTT GCTTGCCCGC GAGAGCAATT CGATTCACTG 
ACTCCCTTAC CAGAACAGGA AGGCCCAACT GTTGGAACAG TGGGAACTTT TGAACTGATG 
AGCTCCAAAG ATTTAGCATA CCAGATGACA ATTTATGATT GGGAACTCTT CAACTGCGTG 
CATGAGCTGG AGCTAATCTA TCACACATTT GGAAGGCATA ATTTTAAAAA GACCACAGCA 
AACTTGGATT TGTTCCTGAG GAGATTTAAT GAAATTCAGT TTTGGGTCGT CACTGAGATC 
TGCCTTTGTT CTCAGCTCAG CAAGCGTGTT CAGCTATTAA AAAAATTTAT TAAGATAGCA 
GCCCACTGTA AGGAGTATAA AAATCTGAAT TCCTTTTTTG CCATCGTCAT GGGACTAAGT 
AACGTTGCTG TGAGCCGCTT GGCACTAACG TGGGAGAAAC TGCCAAGCAA GTTCAAGAAG 
TTCTATGCGG AGTTTGAAAG TTTAATGGAC CCTTCAAGGA ACCACAGGGC CTACAGGCTG 
ACAGTAGCTA AGCTGGAACC TCCTCTCATC CCCTTCATGC CTTTGCTCAT TAAAGATATG 
ACATTTACTC ATGAGGGGAA CAAGACGTTC ATTGACAATC TAGTAAACTT TGAAAAAATG 
CGCATGATTG CAAATACGGC CAGAACAGTG AGATACTACA GGAGCCAACC CTTCAATCCT 
GATGCAGCTC AAGCTAATAA GAACCATCAG GATGTCCGGA GTTATGTACG GCAATTAAAT 
GTGATTGACA ACCAGAGAAC TTTATCACAG ATGTCACACA GATTAGAGCC TCGTCGACCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269829.1
CDS	277..2799
Translation	MAGLLAPPYGVMETGSNNDRIPDKENVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	NM_001282900.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282900.1

ORF Insert Sequence:

ATGGCAGGAC TTCTGGCTCC TCCTTATGGT GTTATGGAAA CGGGCTCTAA CAATGACAGG 
ATTCCTGACA AGGAGAACGT CCCTTCAGAG AAGATCCTCA GAGCTGGAAA AATTTTACGA 
AATGCCATTC TCTCTCGAGC ACCTCACATG ATAAGAGATA GAAAATACCA CCTAAAGACA 
TACAGACAAT GCTGTGTGGG AACTGAACTG GTGGACTGGA TGATGCAGCA GACACCATGT 
GTTCACTCCC GGACTCAAGC TGTTGGCATG TGGCAAGTCC TGTTAGAAGA TGGTGTTCTC 
AACCACGTGG ACCAGGAGCA CCATTTCCAA GACAAATATT TATTCTATCG ATTTCTGGAT 
GATGAGCACG AGGATGCCCC TTTGCCTACT GAGGAGGAGA AGAAGGAGTG TGATGAGGAG 
CTCCAGGACA CCATGCTGCT GCTGTCACAG ATGGGCCCCG ACGCCCACAT GAGGATGATC 
CTTCGCAAAC CACCTGGCCA GAGGACTGTG GATGACCTAG AGATTATCTA TGAGGAGCTT 
CTTCATATTA AAGCCTTATC CCATCTTTCT ACCACAGTGA AACGAGAGTT AGCAGGTGTT 
CTCATTTTTG AGTCTCACGC CAAAGGAGGG ACTGTGTTGT TTAACCAGGG GGAAGAAGGT 
ACCTCCTGGT ACATTATTCT AAAAGGATCA GTGAATGTAG TCATTTACGG CAAGGGTGTG 
GTCTGCACCC TGCATGAAGG AGATGACTTC GGCAAGTTAG CACTAGTGAA TGATGCCCCA 
CGAGCTGCCT CTATCGTCTT ACGAGAAGAT AACTGCCATT TCTTAAGAGT AGACAAGGAG 
GATTTCAACC GGATCCTAAG GGACGTGGAG GCGAATACAG TCAGACTTAA AGAACATGAC 
CAAGATGTCT TGGTGCTGGA GAAGGTCCCA GCAGGGAACA GAGCTTCTAA TCAAGGAAAC 
TCACAGCCTC AGCAAAAGTA TACTGTGATG TCAGGAACAC CTGAAAAAAT TTTAGAGCAT 
TTTCTAGAAA CAATACGCCT TGAGGCAACT TTAAATGAAG CAACAGATTC TGTTTTAAAT 
GACTTTATTA TGATGCACTG TGTTTTTATG CCAAATACCC AGCTTTGCCC GGCACTGGTG 
GCCCACTACC ACGCACAGCC TTCACAAGGT ACAGAACAGG AGAAAATGGA TTATGCCCTC 
AACAATAAGA GGCGAGTCAT CCGCCTGGTT CTACAGTGGG CTGCCATGTA TGGAGACCTC 
CTGCAAGAGG ATGACGTGTC TATGGCCTTC CTGGAGGAGT TTTATGTATC TGTATCAGAT 
GATGCCCGGA TGATTGCTGC CCTCAAGGAG CAACTGCCAG AGTTGGAGAA GATTGTCAAG 
CAAATCTCAG AAGATGCAAA GGCACCACAA AAGAAGCACA AGGTTCTTTT GCAACAGTTC 
AATACGGGCG ATGAGAGAGC CCAGAAGCGC CAGCCTATCC GCGGCTCTGA TGAAGTTCTG 
TTTAAGGTCT ATTGCATGGA CCACACCTAC ACAACCATTC GGGTGCCAGT GGCCACTTCG 
GTGAAGGAAG TCATCAGTGC AGTTGCCGAC AAGCTGGGCT CCGGGGAGGG CCTGATCATA 
GTCAAGATGA GTTCCGGAGG AGAAAAGGTG GTGCTCAAAC CTAATGATGT TTCAGTATTT 
ACGACGCTCA CCATTAATGG ACGCCTGTTT GCTTGCCCGC GAGAGCAATT CGATTCACTG 
ACTCCCTTAC CAGAACAGGA AGGCCCAACT GTTGGAACAG TGGGAACTTT TGAACTGATG 
AGCTCCAAAG ATTTAGCATA CCAGATGACA ATTTATGATT GGGAACTCTT CAACTGCGTG 
CATGAGCTGG AGCTAATCTA TCACACATTT GGAAGGCATA ATTTTAAAAA GACCACAGCA 
AACTTGGATT TGTTCCTGAG GAGATTTAAT GAAATTCAGT TTTGGGTCGT CACTGAGATC 
TGCCTTTGTT CTCAGCTCAG CAAGCGTGTT CAGCTATTAA AAAAATTTAT TAAGATAGCA 
GCCCACTGTA AGGAGTATAA AAATCTGAAT TCCTTTTTTG CCATCGTCAT GGGACTAAGT 
AACGTTGCTG TGAGCCGCTT GGCACTAACG TGGGAGAAAC TGCCAAGCAA GTTCAAGAAG 
TTCTATGCGG AGTTTGAAAG TTTAATGGAC CCTTCAAGGA ACCACAGGGC CTACAGGCTG 
ACAGTAGCTA AGCTGGAACC TCCTCTCATC CCCTTCATGC CTTTGCTCAT TAAAGATATG 
ACATTTACTC ATGAGGGGAA CAAGACGTTC ATTGACAATC TAGTAAACTT TGAAAAAATG 
CGCATGATTG CAAATACGGC CAGAACAGTG AGATACTACA GGAGCCAACC CTTCAATCCT 
GATGCAGCTC AAGCTAATAA GAACCATCAG GATGTCCGGA GTTATGTACG GCAATTAAAT 
GTGATTGACA ACCAGAGAAC TTTATCACAG ATGTCACACA GATTAGAGCC TCGTCGACCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001282901.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269830.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu21563
Clone ID Related Accession (Same CDS sequence)	NM_001282901.1 , NM_001282901.2
Accession Version	NM_001282901.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2376bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-22
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform e
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK311575.1, AK294433.1, U78516.1 and BQ184791.1. Transcript Variant: This variant (5) differs in its 5' UTR, lacks several exons in the 5' coding region, and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (e) is shorter at the N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK294433.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03465403 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG 
GTGGTGCTCA AACCTAATGA TGTTTCAGTA TTTACGACGC TCACCATTAA TGGACGCCTG 
TTTGCTTGCC CGCGAGAGCA ATTCGATTCA CTGACTCCCT TACCAGAACA GGAAGGCCCA 
ACTGTTGGAA CAGTGGGAAC TTTTGAACTG ATGAGCTCCA AAGATTTAGC ATACCAGATG 
ACAATTTATG ATTGGGAACT CTTCAACTGC GTGCATGAGC TGGAGCTAAT CTATCACACA 
TTTGGAAGGC ATAATTTTAA AAAGACCACA GCAAACTTGG ATTTGTTCCT GAGGAGATTT 
AATGAAATTC AGTTTTGGGT CGTCACTGAG ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT 
GTTCAGCTAT TAAAAAAATT TATTAAGATA GCAGCCCACT GTAAGGAGTA TAAAAATCTG 
AATTCCTTTT TTGCCATCGT CATGGGACTA AGTAACGTTG CTGTGAGCCG CTTGGCACTA 
ACGTGGGAGA AACTGCCAAG CAAGTTCAAG AAGTTCTATG CGGAGTTTGA AAGTTTAATG 
GACCCTTCAA GGAACCACAG GGCCTACAGG CTGACAGTAG CTAAGCTGGA ACCTCCTCTC 
ATCCCCTTCA TGCCTTTGCT CATTAAAGAT ATGACATTTA CTCATGAGGG GAACAAGACG 
TTCATTGACA ATCTAGTAAA CTTTGAAAAA ATGCGCATGA TTGCAAATAC GGCCAGAACA 
GTGAGATACT ACAGGAGCCA ACCCTTCAAT CCTGATGCAG CTCAAGCTAA TAAGAACCAT 
CAGGATGTCC GGAGTTATGT ACGGCAATTA AATGTGATTG ACAACCAGAG AACTTTATCA 
CAGATGTCAC ACAGATTAGA GCCTCGTCGA CCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269830.1
CDS	212..2587
Translation	MIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	NM_001282901.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282901.1

ORF Insert Sequence:

ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG 
GTGGTGCTCA AACCTAATGA TGTTTCAGTA TTTACGACGC TCACCATTAA TGGACGCCTG 
TTTGCTTGCC CGCGAGAGCA ATTCGATTCA CTGACTCCCT TACCAGAACA GGAAGGCCCA 
ACTGTTGGAA CAGTGGGAAC TTTTGAACTG ATGAGCTCCA AAGATTTAGC ATACCAGATG 
ACAATTTATG ATTGGGAACT CTTCAACTGC GTGCATGAGC TGGAGCTAAT CTATCACACA 
TTTGGAAGGC ATAATTTTAA AAAGACCACA GCAAACTTGG ATTTGTTCCT GAGGAGATTT 
AATGAAATTC AGTTTTGGGT CGTCACTGAG ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT 
GTTCAGCTAT TAAAAAAATT TATTAAGATA GCAGCCCACT GTAAGGAGTA TAAAAATCTG 
AATTCCTTTT TTGCCATCGT CATGGGACTA AGTAACGTTG CTGTGAGCCG CTTGGCACTA 
ACGTGGGAGA AACTGCCAAG CAAGTTCAAG AAGTTCTATG CGGAGTTTGA AAGTTTAATG 
GACCCTTCAA GGAACCACAG GGCCTACAGG CTGACAGTAG CTAAGCTGGA ACCTCCTCTC 
ATCCCCTTCA TGCCTTTGCT CATTAAAGAT ATGACATTTA CTCATGAGGG GAACAAGACG 
TTCATTGACA ATCTAGTAAA CTTTGAAAAA ATGCGCATGA TTGCAAATAC GGCCAGAACA 
GTGAGATACT ACAGGAGCCA ACCCTTCAAT CCTGATGCAG CTCAAGCTAA TAAGAACCAT 
CAGGATGTCC GGAGTTATGT ACGGCAATTA AATGTGATTG ACAACCAGAG AACTTTATCA 
CAGATGTCAC ACAGATTAGA GCCTCGTCGA CCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001282899.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269828.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 3, mRNA.

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CloneID	OHu21628
Clone ID Related Accession (Same CDS sequence)	NM_001282899.1 , NM_001282899.2
Accession Version	NM_001282899.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2577bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-22
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC335305.1, AK316072.1, U78516.1 and BQ184791.1. On Sep 20, 2013 this sequence version replaced XM_005246247.1. Transcript Variant: This variant (3) differs in its 5' UTR, lacks several exons in the 5' coding region, and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (c) is shorter at the N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.8134.1, SRR1803614.117433.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGGAC TTCTGGCTCC TCCTTATGGT GTTATGGAAA CGGGCTCTAA CAATGACAGG 
ATTCCTGACA AGGAGAACAC ACCTCTCATT GAACCTCACG TTCCTCTTCG TCCTGCTAAC 
ACCATTACCA AGGTCCCTTC AGAGAAGATC CTCAGAGCTG GAAAAATTTT ACGAAATGCC 
ATTCTCTCTC GAGCACCTCA CATGATAAGA GATAGAAAAT ACCACCTAAA GACATACAGA 
CAATGCTGTG TGGGAACTGA ACTGGTGGAC TGGATGATGC AGCAGACACC ATGTGTTCAC 
TCCCGGACTC AAGCTGTTGG CATGTGGCAA GTCCTGTTAG AAGATGGTGT TCTCAACCAC 
GTGGACCAGG AGCACCATTT CCAAGACAAA TATTTATTCT ATCGATTTCT GGATGATGAG 
CACGAGGATG CCCCTTTGCC TACTGAGGAG GAGAAGAAGG AGTGTGATGA GGAGCTCCAG 
GACACCATGC TGCTGCTGTC ACAGATGGGC CCCGACGCCC ACATGAGGAT GATCCTTCGC 
AAACCACCTG GCCAGAGGAC TGTGGATGAC CTAGAGATTA TCTATGAGGA GCTTCTTCAT 
ATTAAAGCCT TATCCCATCT TTCTACCACA GTGAAACGAG AGTTAGCAGG TGTTCTCATT 
TTTGAGTCTC ACGCCAAAGG AGGGACTGTG TTGTTTAACC AGGGGGAAGA AGGTACCTCC 
TGGTACATTA TTCTAAAAGG ATCAGTGAAT GTAGTCATTT ACGGCAAGGG TGTGGTCTGC 
ACCCTGCATG AAGGAGATGA CTTCGGCAAG TTAGCACTAG TGAATGATGC CCCACGAGCT 
GCCTCTATCG TCTTACGAGA AGATAACTGC CATTTCTTAA GAGTAGACAA GGAGGATTTC 
AACCGGATCC TAAGGGACGT GGAGGCGAAT ACAGTCAGAC TTAAAGAACA TGACCAAGAT 
GTCTTGGTGC TGGAGAAGGT CCCAGCAGGG AACAGAGCTT CTAATCAAGG AAACTCACAG 
CCTCAGCAAA AGTATACTGT GATGTCAGGA ACACCTGAAA AAATTTTAGA GCATTTTCTA 
GAAACAATAC GCCTTGAGGC AACTTTAAAT GAAGCAACAG ATTCTGTTTT AAATGACTTT 
ATTATGATGC ACTGTGTTTT TATGCCAAAT ACCCAGCTTT GCCCGGCACT GGTGGCCCAC 
TACCACGCAC AGCCTTCACA AGGTACAGAA CAGGAGAAAA TGGATTATGC CCTCAACAAT 
AAGAGGCGAG TCATCCGCCT GGTTCTACAG TGGGCTGCCA TGTATGGAGA CCTCCTGCAA 
GAGGATGACG TGTCTATGGC CTTCCTGGAG GAGTTTTATG TATCTGTATC AGATGATGCC 
CGGATGATTG CTGCCCTCAA GGAGCAACTG CCAGAGTTGG AGAAGATTGT CAAGCAAATC 
TCAGAAGATG CAAAGGCACC ACAAAAGAAG CACAAGGTTC TTTTGCAACA GTTCAATACG 
GGCGATGAGA GAGCCCAGAA GCGCCAGCCT ATCCGCGGCT CTGATGAAGT TCTGTTTAAG 
GTCTATTGCA TGGACCACAC CTACACAACC ATTCGGGTGC CAGTGGCCAC TTCGGTGAAG 
GAAGTCATCA GTGCAGTTGC CGACAAGCTG GGCTCCGGGG AGGGCCTGAT CATAGTCAAG 
ATGAGTTCCG GAGGAGAAAA GGTGGTGCTC AAACCTAATG ATGTTTCAGT ATTTACGACG 
CTCACCATTA ATGGACGCCT GTTTGCTTGC CCGCGAGAGC AATTCGATTC ACTGACTCCC 
TTACCAGAAC AGGAAGGCCC AACTGTTGGA ACAGTGGGAA CTTTTGAACT GATGAGCTCC 
AAAGATTTAG CATACCAGAT GACAATTTAT GATTGGGAAC TCTTCAACTG CGTGCATGAG 
CTGGAGCTAA TCTATCACAC ATTTGGAAGG CATAATTTTA AAAAGACCAC AGCAAACTTG 
GATTTGTTCC TGAGGAGATT TAATGAAATT CAGTTTTGGG TCGTCACTGA GATCTGCCTT 
TGTTCTCAGC TCAGCAAGCG TGTTCAGCTA TTAAAAAAAT TTATTAAGAT AGCAGCCCAC 
TGTAAGGAGT ATAAAAATCT GAATTCCTTT TTTGCCATCG TCATGGGACT AAGTAACGTT 
GCTGTGAGCC GCTTGGCACT AACGTGGGAG AAACTGCCAA GCAAGTTCAA GAAGTTCTAT 
GCGGAGTTTG AAAGTTTAAT GGACCCTTCA AGGAACCACA GGGCCTACAG GCTGACAGTA 
GCTAAGCTGG AACCTCCTCT CATCCCCTTC ATGCCTTTGC TCATTAAAGA TATGACATTT 
ACTCATGAGG GGAACAAGAC GTTCATTGAC AATCTAGTAA ACTTTGAAAA AATGCGCATG 
ATTGCAAATA CGGCCAGAAC AGTGAGATAC TACAGGAGCC AACCCTTCAA TCCTGATGCA 
GCTCAAGCTA ATAAGAACCA TCAGGATGTC CGGAGTTATG TACGGCAATT AAATGTGATT 
GACAACCAGA GAACTTTATC ACAGATGTCA CACAGATTAG AGCCTCGTCG ACCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269828.1
CDS	277..2853
Translation	MAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	NM_001282899.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282899.1

ORF Insert Sequence:

ATGGCAGGAC TTCTGGCTCC TCCTTATGGT GTTATGGAAA CGGGCTCTAA CAATGACAGG 
ATTCCTGACA AGGAGAACAC ACCTCTCATT GAACCTCACG TTCCTCTTCG TCCTGCTAAC 
ACCATTACCA AGGTCCCTTC AGAGAAGATC CTCAGAGCTG GAAAAATTTT ACGAAATGCC 
ATTCTCTCTC GAGCACCTCA CATGATAAGA GATAGAAAAT ACCACCTAAA GACATACAGA 
CAATGCTGTG TGGGAACTGA ACTGGTGGAC TGGATGATGC AGCAGACACC ATGTGTTCAC 
TCCCGGACTC AAGCTGTTGG CATGTGGCAA GTCCTGTTAG AAGATGGTGT TCTCAACCAC 
GTGGACCAGG AGCACCATTT CCAAGACAAA TATTTATTCT ATCGATTTCT GGATGATGAG 
CACGAGGATG CCCCTTTGCC TACTGAGGAG GAGAAGAAGG AGTGTGATGA GGAGCTCCAG 
GACACCATGC TGCTGCTGTC ACAGATGGGC CCCGACGCCC ACATGAGGAT GATCCTTCGC 
AAACCACCTG GCCAGAGGAC TGTGGATGAC CTAGAGATTA TCTATGAGGA GCTTCTTCAT 
ATTAAAGCCT TATCCCATCT TTCTACCACA GTGAAACGAG AGTTAGCAGG TGTTCTCATT 
TTTGAGTCTC ACGCCAAAGG AGGGACTGTG TTGTTTAACC AGGGGGAAGA AGGTACCTCC 
TGGTACATTA TTCTAAAAGG ATCAGTGAAT GTAGTCATTT ACGGCAAGGG TGTGGTCTGC 
ACCCTGCATG AAGGAGATGA CTTCGGCAAG TTAGCACTAG TGAATGATGC CCCACGAGCT 
GCCTCTATCG TCTTACGAGA AGATAACTGC CATTTCTTAA GAGTAGACAA GGAGGATTTC 
AACCGGATCC TAAGGGACGT GGAGGCGAAT ACAGTCAGAC TTAAAGAACA TGACCAAGAT 
GTCTTGGTGC TGGAGAAGGT CCCAGCAGGG AACAGAGCTT CTAATCAAGG AAACTCACAG 
CCTCAGCAAA AGTATACTGT GATGTCAGGA ACACCTGAAA AAATTTTAGA GCATTTTCTA 
GAAACAATAC GCCTTGAGGC AACTTTAAAT GAAGCAACAG ATTCTGTTTT AAATGACTTT 
ATTATGATGC ACTGTGTTTT TATGCCAAAT ACCCAGCTTT GCCCGGCACT GGTGGCCCAC 
TACCACGCAC AGCCTTCACA AGGTACAGAA CAGGAGAAAA TGGATTATGC CCTCAACAAT 
AAGAGGCGAG TCATCCGCCT GGTTCTACAG TGGGCTGCCA TGTATGGAGA CCTCCTGCAA 
GAGGATGACG TGTCTATGGC CTTCCTGGAG GAGTTTTATG TATCTGTATC AGATGATGCC 
CGGATGATTG CTGCCCTCAA GGAGCAACTG CCAGAGTTGG AGAAGATTGT CAAGCAAATC 
TCAGAAGATG CAAAGGCACC ACAAAAGAAG CACAAGGTTC TTTTGCAACA GTTCAATACG 
GGCGATGAGA GAGCCCAGAA GCGCCAGCCT ATCCGCGGCT CTGATGAAGT TCTGTTTAAG 
GTCTATTGCA TGGACCACAC CTACACAACC ATTCGGGTGC CAGTGGCCAC TTCGGTGAAG 
GAAGTCATCA GTGCAGTTGC CGACAAGCTG GGCTCCGGGG AGGGCCTGAT CATAGTCAAG 
ATGAGTTCCG GAGGAGAAAA GGTGGTGCTC AAACCTAATG ATGTTTCAGT ATTTACGACG 
CTCACCATTA ATGGACGCCT GTTTGCTTGC CCGCGAGAGC AATTCGATTC ACTGACTCCC 
TTACCAGAAC AGGAAGGCCC AACTGTTGGA ACAGTGGGAA CTTTTGAACT GATGAGCTCC 
AAAGATTTAG CATACCAGAT GACAATTTAT GATTGGGAAC TCTTCAACTG CGTGCATGAG 
CTGGAGCTAA TCTATCACAC ATTTGGAAGG CATAATTTTA AAAAGACCAC AGCAAACTTG 
GATTTGTTCC TGAGGAGATT TAATGAAATT CAGTTTTGGG TCGTCACTGA GATCTGCCTT 
TGTTCTCAGC TCAGCAAGCG TGTTCAGCTA TTAAAAAAAT TTATTAAGAT AGCAGCCCAC 
TGTAAGGAGT ATAAAAATCT GAATTCCTTT TTTGCCATCG TCATGGGACT AAGTAACGTT 
GCTGTGAGCC GCTTGGCACT AACGTGGGAG AAACTGCCAA GCAAGTTCAA GAAGTTCTAT 
GCGGAGTTTG AAAGTTTAAT GGACCCTTCA AGGAACCACA GGGCCTACAG GCTGACAGTA 
GCTAAGCTGG AACCTCCTCT CATCCCCTTC ATGCCTTTGC TCATTAAAGA TATGACATTT 
ACTCATGAGG GGAACAAGAC GTTCATTGAC AATCTAGTAA ACTTTGAAAA AATGCGCATG 
ATTGCAAATA CGGCCAGAAC AGTGAGATAC TACAGGAGCC AACCCTTCAA TCCTGATGCA 
GCTCAAGCTA ATAAGAACCA TCAGGATGTC CGGAGTTATG TACGGCAATT AAATGTGATT 
GACAACCAGA GAACTTTATC ACAGATGTCA CACAGATTAG AGCCTCGTCG ACCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( XM_006712205.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006712268.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X5, mRNA.

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CloneID	OHu20982
Clone ID Related Accession (Same CDS sequence)	NM_001282900.2 , NM_001282900.1 , XM_006712205.3
Accession Version	XM_006712205.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2523bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006712205.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGGAC TTCTGGCTCC TCCTTATGGT GTTATGGAAA CGGGCTCTAA CAATGACAGG 
ATTCCTGACA AGGAGAACGT CCCTTCAGAG AAGATCCTCA GAGCTGGAAA AATTTTACGA 
AATGCCATTC TCTCTCGAGC ACCTCACATG ATAAGAGATA GAAAATACCA CCTAAAGACA 
TACAGACAAT GCTGTGTGGG AACTGAACTG GTGGACTGGA TGATGCAGCA GACACCATGT 
GTTCACTCCC GGACTCAAGC TGTTGGCATG TGGCAAGTCC TGTTAGAAGA TGGTGTTCTC 
AACCACGTGG ACCAGGAGCA CCATTTCCAA GACAAATATT TATTCTATCG ATTTCTGGAT 
GATGAGCACG AGGATGCCCC TTTGCCTACT GAGGAGGAGA AGAAGGAGTG TGATGAGGAG 
CTCCAGGACA CCATGCTGCT GCTGTCACAG ATGGGCCCCG ACGCCCACAT GAGGATGATC 
CTTCGCAAAC CACCTGGCCA GAGGACTGTG GATGACCTAG AGATTATCTA TGAGGAGCTT 
CTTCATATTA AAGCCTTATC CCATCTTTCT ACCACAGTGA AACGAGAGTT AGCAGGTGTT 
CTCATTTTTG AGTCTCACGC CAAAGGAGGG ACTGTGTTGT TTAACCAGGG GGAAGAAGGT 
ACCTCCTGGT ACATTATTCT AAAAGGATCA GTGAATGTAG TCATTTACGG CAAGGGTGTG 
GTCTGCACCC TGCATGAAGG AGATGACTTC GGCAAGTTAG CACTAGTGAA TGATGCCCCA 
CGAGCTGCCT CTATCGTCTT ACGAGAAGAT AACTGCCATT TCTTAAGAGT AGACAAGGAG 
GATTTCAACC GGATCCTAAG GGACGTGGAG GCGAATACAG TCAGACTTAA AGAACATGAC 
CAAGATGTCT TGGTGCTGGA GAAGGTCCCA GCAGGGAACA GAGCTTCTAA TCAAGGAAAC 
TCACAGCCTC AGCAAAAGTA TACTGTGATG TCAGGAACAC CTGAAAAAAT TTTAGAGCAT 
TTTCTAGAAA CAATACGCCT TGAGGCAACT TTAAATGAAG CAACAGATTC TGTTTTAAAT 
GACTTTATTA TGATGCACTG TGTTTTTATG CCAAATACCC AGCTTTGCCC GGCACTGGTG 
GCCCACTACC ACGCACAGCC TTCACAAGGT ACAGAACAGG AGAAAATGGA TTATGCCCTC 
AACAATAAGA GGCGAGTCAT CCGCCTGGTT CTACAGTGGG CTGCCATGTA TGGAGACCTC 
CTGCAAGAGG ATGACGTGTC TATGGCCTTC CTGGAGGAGT TTTATGTATC TGTATCAGAT 
GATGCCCGGA TGATTGCTGC CCTCAAGGAG CAACTGCCAG AGTTGGAGAA GATTGTCAAG 
CAAATCTCAG AAGATGCAAA GGCACCACAA AAGAAGCACA AGGTTCTTTT GCAACAGTTC 
AATACGGGCG ATGAGAGAGC CCAGAAGCGC CAGCCTATCC GCGGCTCTGA TGAAGTTCTG 
TTTAAGGTCT ATTGCATGGA CCACACCTAC ACAACCATTC GGGTGCCAGT GGCCACTTCG 
GTGAAGGAAG TCATCAGTGC AGTTGCCGAC AAGCTGGGCT CCGGGGAGGG CCTGATCATA 
GTCAAGATGA GTTCCGGAGG AGAAAAGGTG GTGCTCAAAC CTAATGATGT TTCAGTATTT 
ACGACGCTCA CCATTAATGG ACGCCTGTTT GCTTGCCCGC GAGAGCAATT CGATTCACTG 
ACTCCCTTAC CAGAACAGGA AGGCCCAACT GTTGGAACAG TGGGAACTTT TGAACTGATG 
AGCTCCAAAG ATTTAGCATA CCAGATGACA ATTTATGATT GGGAACTCTT CAACTGCGTG 
CATGAGCTGG AGCTAATCTA TCACACATTT GGAAGGCATA ATTTTAAAAA GACCACAGCA 
AACTTGGATT TGTTCCTGAG GAGATTTAAT GAAATTCAGT TTTGGGTCGT CACTGAGATC 
TGCCTTTGTT CTCAGCTCAG CAAGCGTGTT CAGCTATTAA AAAAATTTAT TAAGATAGCA 
GCCCACTGTA AGGAGTATAA AAATCTGAAT TCCTTTTTTG CCATCGTCAT GGGACTAAGT 
AACGTTGCTG TGAGCCGCTT GGCACTAACG TGGGAGAAAC TGCCAAGCAA GTTCAAGAAG 
TTCTATGCGG AGTTTGAAAG TTTAATGGAC CCTTCAAGGA ACCACAGGGC CTACAGGCTG 
ACAGTAGCTA AGCTGGAACC TCCTCTCATC CCCTTCATGC CTTTGCTCAT TAAAGATATG 
ACATTTACTC ATGAGGGGAA CAAGACGTTC ATTGACAATC TAGTAAACTT TGAAAAAATG 
CGCATGATTG CAAATACGGC CAGAACAGTG AGATACTACA GGAGCCAACC CTTCAATCCT 
GATGCAGCTC AAGCTAATAA GAACCATCAG GATGTCCGGA GTTATGTACG GCAATTAAAT 
GTGATTGACA ACCAGAGAAC TTTATCACAG ATGTCACACA GATTAGAGCC TCGTCGACCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006712268.1
CDS	519..3041
Translation	MAGLLAPPYGVMETGSNNDRIPDKENVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	XM_006712205.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006712205.3

ORF Insert Sequence:

ATGGCAGGAC TTCTGGCTCC TCCTTATGGT GTTATGGAAA CGGGCTCTAA CAATGACAGG 
ATTCCTGACA AGGAGAACGT CCCTTCAGAG AAGATCCTCA GAGCTGGAAA AATTTTACGA 
AATGCCATTC TCTCTCGAGC ACCTCACATG ATAAGAGATA GAAAATACCA CCTAAAGACA 
TACAGACAAT GCTGTGTGGG AACTGAACTG GTGGACTGGA TGATGCAGCA GACACCATGT 
GTTCACTCCC GGACTCAAGC TGTTGGCATG TGGCAAGTCC TGTTAGAAGA TGGTGTTCTC 
AACCACGTGG ACCAGGAGCA CCATTTCCAA GACAAATATT TATTCTATCG ATTTCTGGAT 
GATGAGCACG AGGATGCCCC TTTGCCTACT GAGGAGGAGA AGAAGGAGTG TGATGAGGAG 
CTCCAGGACA CCATGCTGCT GCTGTCACAG ATGGGCCCCG ACGCCCACAT GAGGATGATC 
CTTCGCAAAC CACCTGGCCA GAGGACTGTG GATGACCTAG AGATTATCTA TGAGGAGCTT 
CTTCATATTA AAGCCTTATC CCATCTTTCT ACCACAGTGA AACGAGAGTT AGCAGGTGTT 
CTCATTTTTG AGTCTCACGC CAAAGGAGGG ACTGTGTTGT TTAACCAGGG GGAAGAAGGT 
ACCTCCTGGT ACATTATTCT AAAAGGATCA GTGAATGTAG TCATTTACGG CAAGGGTGTG 
GTCTGCACCC TGCATGAAGG AGATGACTTC GGCAAGTTAG CACTAGTGAA TGATGCCCCA 
CGAGCTGCCT CTATCGTCTT ACGAGAAGAT AACTGCCATT TCTTAAGAGT AGACAAGGAG 
GATTTCAACC GGATCCTAAG GGACGTGGAG GCGAATACAG TCAGACTTAA AGAACATGAC 
CAAGATGTCT TGGTGCTGGA GAAGGTCCCA GCAGGGAACA GAGCTTCTAA TCAAGGAAAC 
TCACAGCCTC AGCAAAAGTA TACTGTGATG TCAGGAACAC CTGAAAAAAT TTTAGAGCAT 
TTTCTAGAAA CAATACGCCT TGAGGCAACT TTAAATGAAG CAACAGATTC TGTTTTAAAT 
GACTTTATTA TGATGCACTG TGTTTTTATG CCAAATACCC AGCTTTGCCC GGCACTGGTG 
GCCCACTACC ACGCACAGCC TTCACAAGGT ACAGAACAGG AGAAAATGGA TTATGCCCTC 
AACAATAAGA GGCGAGTCAT CCGCCTGGTT CTACAGTGGG CTGCCATGTA TGGAGACCTC 
CTGCAAGAGG ATGACGTGTC TATGGCCTTC CTGGAGGAGT TTTATGTATC TGTATCAGAT 
GATGCCCGGA TGATTGCTGC CCTCAAGGAG CAACTGCCAG AGTTGGAGAA GATTGTCAAG 
CAAATCTCAG AAGATGCAAA GGCACCACAA AAGAAGCACA AGGTTCTTTT GCAACAGTTC 
AATACGGGCG ATGAGAGAGC CCAGAAGCGC CAGCCTATCC GCGGCTCTGA TGAAGTTCTG 
TTTAAGGTCT ATTGCATGGA CCACACCTAC ACAACCATTC GGGTGCCAGT GGCCACTTCG 
GTGAAGGAAG TCATCAGTGC AGTTGCCGAC AAGCTGGGCT CCGGGGAGGG CCTGATCATA 
GTCAAGATGA GTTCCGGAGG AGAAAAGGTG GTGCTCAAAC CTAATGATGT TTCAGTATTT 
ACGACGCTCA CCATTAATGG ACGCCTGTTT GCTTGCCCGC GAGAGCAATT CGATTCACTG 
ACTCCCTTAC CAGAACAGGA AGGCCCAACT GTTGGAACAG TGGGAACTTT TGAACTGATG 
AGCTCCAAAG ATTTAGCATA CCAGATGACA ATTTATGATT GGGAACTCTT CAACTGCGTG 
CATGAGCTGG AGCTAATCTA TCACACATTT GGAAGGCATA ATTTTAAAAA GACCACAGCA 
AACTTGGATT TGTTCCTGAG GAGATTTAAT GAAATTCAGT TTTGGGTCGT CACTGAGATC 
TGCCTTTGTT CTCAGCTCAG CAAGCGTGTT CAGCTATTAA AAAAATTTAT TAAGATAGCA 
GCCCACTGTA AGGAGTATAA AAATCTGAAT TCCTTTTTTG CCATCGTCAT GGGACTAAGT 
AACGTTGCTG TGAGCCGCTT GGCACTAACG TGGGAGAAAC TGCCAAGCAA GTTCAAGAAG 
TTCTATGCGG AGTTTGAAAG TTTAATGGAC CCTTCAAGGA ACCACAGGGC CTACAGGCTG 
ACAGTAGCTA AGCTGGAACC TCCTCTCATC CCCTTCATGC CTTTGCTCAT TAAAGATATG 
ACATTTACTC ATGAGGGGAA CAAGACGTTC ATTGACAATC TAGTAAACTT TGAAAAAATG 
CGCATGATTG CAAATACGGC CAGAACAGTG AGATACTACA GGAGCCAACC CTTCAATCCT 
GATGCAGCTC AAGCTAATAA GAACCATCAG GATGTCCGGA GTTATGTACG GCAATTAAAT 
GTGATTGACA ACCAGAGAAC TTTATCACAG ATGTCACACA GATTAGAGCC TCGTCGACCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( XM_005246246.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005246303.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu35775
Clone ID Related Accession (Same CDS sequence)	XM_005246246.3 , XM_005246246.2 , NM_001375866.1
Accession Version	XM_005246246.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2982bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-12
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005246246.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END##

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACGTC 
CCTTCAGAGA AGATCCTCAG AGCTGGAAAA ATTTTACGAA ATGCCATTCT CTCTCGAGCA 
CCTCACATGA TAAGAGATAG AAAATACCAC CTAAAGACAT ACAGACAATG CTGTGTGGGA 
ACTGAACTGG TGGACTGGAT GATGCAGCAG ACACCATGTG TTCACTCCCG GACTCAAGCT 
GTTGGCATGT GGCAAGTCCT GTTAGAAGAT GGTGTTCTCA ACCACGTGGA CCAGGAGCAC 
CATTTCCAAG ACAAATATTT ATTCTATCGA TTTCTGGATG ATGAGCACGA GGATGCCCCT 
TTGCCTACTG AGGAGGAGAA GAAGGAGTGT GATGAGGAGC TCCAGGACAC CATGCTGCTG 
CTGTCACAGA TGGGCCCCGA CGCCCACATG AGGATGATCC TTCGCAAACC ACCTGGCCAG 
AGGACTGTGG ATGACCTAGA GATTATCTAT GAGGAGCTTC TTCATATTAA AGCCTTATCC 
CATCTTTCTA CCACAGTGAA ACGAGAGTTA GCAGGTGTTC TCATTTTTGA GTCTCACGCC 
AAAGGAGGGA CTGTGTTGTT TAACCAGGGG GAAGAAGGTA CCTCCTGGTA CATTATTCTA 
AAAGGATCAG TGAATGTAGT CATTTACGGC AAGGGTGTGG TCTGCACCCT GCATGAAGGA 
GATGACTTCG GCAAGTTAGC ACTAGTGAAT GATGCCCCAC GAGCTGCCTC TATCGTCTTA 
CGAGAAGATA ACTGCCATTT CTTAAGAGTA GACAAGGAGG ATTTCAACCG GATCCTAAGG 
GACGTGGAGG CGAATACAGT CAGACTTAAA GAACATGACC AAGATGTCTT GGTGCTGGAG 
AAGGTCCCAG CAGGGAACAG AGCTTCTAAT CAAGGAAACT CACAGCCTCA GCAAAAGTAT 
ACTGTGATGT CAGGAACACC TGAAAAAATT TTAGAGCATT TTCTAGAAAC AATACGCCTT 
GAGGCAACTT TAAATGAAGC AACAGATTCT GTTTTAAATG ACTTTATTAT GATGCACTGT 
GTTTTTATGC CAAATACCCA GCTTTGCCCG GCACTGGTGG CCCACTACCA CGCACAGCCT 
TCACAAGGTA CAGAACAGGA GAAAATGGAT TATGCCCTCA ACAATAAGAG GCGAGTCATC 
CGCCTGGTTC TACAGTGGGC TGCCATGTAT GGAGACCTCC TGCAAGAGGA TGACGTGTCT 
ATGGCCTTCC TGGAGGAGTT TTATGTATCT GTATCAGATG ATGCCCGGAT GATTGCTGCC 
CTCAAGGAGC AACTGCCAGA GTTGGAGAAG ATTGTCAAGC AAATCTCAGA AGATGCAAAG 
GCACCACAAA AGAAGCACAA GGTTCTTTTG CAACAGTTCA ATACGGGCGA TGAGAGAGCC 
CAGAAGCGCC AGCCTATCCG CGGCTCTGAT GAAGTTCTGT TTAAGGTCTA TTGCATGGAC 
CACACCTACA CAACCATTCG GGTGCCAGTG GCCACTTCGG TGAAGGAAGT CATCAGTGCA 
GTTGCCGACA AGCTGGGCTC CGGGGAGGGC CTGATCATAG TCAAGATGAG TTCCGGAGGA 
GAAAAGGTGG TGCTCAAACC TAATGATGTT TCAGTATTTA CGACGCTCAC CATTAATGGA 
CGCCTGTTTG CTTGCCCGCG AGAGCAATTC GATTCACTGA CTCCCTTACC AGAACAGGAA 
GGCCCAACTG TTGGAACAGT GGGAACTTTT GAACTGATGA GCTCCAAAGA TTTAGCATAC 
CAGATGACAA TTTATGATTG GGAACTCTTC AACTGCGTGC ATGAGCTGGA GCTAATCTAT 
CACACATTTG GAAGGCATAA TTTTAAAAAG ACCACAGCAA ACTTGGATTT GTTCCTGAGG 
AGATTTAATG AAATTCAGTT TTGGGTCGTC ACTGAGATCT GCCTTTGTTC TCAGCTCAGC 
AAGCGTGTTC AGCTATTAAA AAAATTTATT AAGATAGCAG CCCACTGTAA GGAGTATAAA 
AATCTGAATT CCTTTTTTGC CATCGTCATG GGACTAAGTA ACGTTGCTGT GAGCCGCTTG 
GCACTAACGT GGGAGAAACT GCCAAGCAAG TTCAAGAAGT TCTATGCGGA GTTTGAAAGT 
TTAATGGACC CTTCAAGGAA CCACAGGGCC TACAGGCTGA CAGTAGCTAA GCTGGAACCT 
CCTCTCATCC CCTTCATGCC TTTGCTCATT AAAGATATGA CATTTACTCA TGAGGGGAAC 
AAGACGTTCA TTGACAATCT AGTAAACTTT GAAAAAATGC GCATGATTGC AAATACGGCC 
AGAACAGTGA GATACTACAG GAGCCAACCC TTCAATCCTG ATGCAGCTCA AGCTAATAAG 
AACCATCAGG ATGTCCGGAG TTATGTACGG CAATTAAATG TGATTGACAA CCAGAGAACT 
TTATCACAGA TGTCACACAG ATTAGAGCCT CGTCGACCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005246303.1
CDS	66..3047
Translation	MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	XM_005246246.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005246246.3

ORF Insert Sequence:

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACGTC 
CCTTCAGAGA AGATCCTCAG AGCTGGAAAA ATTTTACGAA ATGCCATTCT CTCTCGAGCA 
CCTCACATGA TAAGAGATAG AAAATACCAC CTAAAGACAT ACAGACAATG CTGTGTGGGA 
ACTGAACTGG TGGACTGGAT GATGCAGCAG ACACCATGTG TTCACTCCCG GACTCAAGCT 
GTTGGCATGT GGCAAGTCCT GTTAGAAGAT GGTGTTCTCA ACCACGTGGA CCAGGAGCAC 
CATTTCCAAG ACAAATATTT ATTCTATCGA TTTCTGGATG ATGAGCACGA GGATGCCCCT 
TTGCCTACTG AGGAGGAGAA GAAGGAGTGT GATGAGGAGC TCCAGGACAC CATGCTGCTG 
CTGTCACAGA TGGGCCCCGA CGCCCACATG AGGATGATCC TTCGCAAACC ACCTGGCCAG 
AGGACTGTGG ATGACCTAGA GATTATCTAT GAGGAGCTTC TTCATATTAA AGCCTTATCC 
CATCTTTCTA CCACAGTGAA ACGAGAGTTA GCAGGTGTTC TCATTTTTGA GTCTCACGCC 
AAAGGAGGGA CTGTGTTGTT TAACCAGGGG GAAGAAGGTA CCTCCTGGTA CATTATTCTA 
AAAGGATCAG TGAATGTAGT CATTTACGGC AAGGGTGTGG TCTGCACCCT GCATGAAGGA 
GATGACTTCG GCAAGTTAGC ACTAGTGAAT GATGCCCCAC GAGCTGCCTC TATCGTCTTA 
CGAGAAGATA ACTGCCATTT CTTAAGAGTA GACAAGGAGG ATTTCAACCG GATCCTAAGG 
GACGTGGAGG CGAATACAGT CAGACTTAAA GAACATGACC AAGATGTCTT GGTGCTGGAG 
AAGGTCCCAG CAGGGAACAG AGCTTCTAAT CAAGGAAACT CACAGCCTCA GCAAAAGTAT 
ACTGTGATGT CAGGAACACC TGAAAAAATT TTAGAGCATT TTCTAGAAAC AATACGCCTT 
GAGGCAACTT TAAATGAAGC AACAGATTCT GTTTTAAATG ACTTTATTAT GATGCACTGT 
GTTTTTATGC CAAATACCCA GCTTTGCCCG GCACTGGTGG CCCACTACCA CGCACAGCCT 
TCACAAGGTA CAGAACAGGA GAAAATGGAT TATGCCCTCA ACAATAAGAG GCGAGTCATC 
CGCCTGGTTC TACAGTGGGC TGCCATGTAT GGAGACCTCC TGCAAGAGGA TGACGTGTCT 
ATGGCCTTCC TGGAGGAGTT TTATGTATCT GTATCAGATG ATGCCCGGAT GATTGCTGCC 
CTCAAGGAGC AACTGCCAGA GTTGGAGAAG ATTGTCAAGC AAATCTCAGA AGATGCAAAG 
GCACCACAAA AGAAGCACAA GGTTCTTTTG CAACAGTTCA ATACGGGCGA TGAGAGAGCC 
CAGAAGCGCC AGCCTATCCG CGGCTCTGAT GAAGTTCTGT TTAAGGTCTA TTGCATGGAC 
CACACCTACA CAACCATTCG GGTGCCAGTG GCCACTTCGG TGAAGGAAGT CATCAGTGCA 
GTTGCCGACA AGCTGGGCTC CGGGGAGGGC CTGATCATAG TCAAGATGAG TTCCGGAGGA 
GAAAAGGTGG TGCTCAAACC TAATGATGTT TCAGTATTTA CGACGCTCAC CATTAATGGA 
CGCCTGTTTG CTTGCCCGCG AGAGCAATTC GATTCACTGA CTCCCTTACC AGAACAGGAA 
GGCCCAACTG TTGGAACAGT GGGAACTTTT GAACTGATGA GCTCCAAAGA TTTAGCATAC 
CAGATGACAA TTTATGATTG GGAACTCTTC AACTGCGTGC ATGAGCTGGA GCTAATCTAT 
CACACATTTG GAAGGCATAA TTTTAAAAAG ACCACAGCAA ACTTGGATTT GTTCCTGAGG 
AGATTTAATG AAATTCAGTT TTGGGTCGTC ACTGAGATCT GCCTTTGTTC TCAGCTCAGC 
AAGCGTGTTC AGCTATTAAA AAAATTTATT AAGATAGCAG CCCACTGTAA GGAGTATAAA 
AATCTGAATT CCTTTTTTGC CATCGTCATG GGACTAAGTA ACGTTGCTGT GAGCCGCTTG 
GCACTAACGT GGGAGAAACT GCCAAGCAAG TTCAAGAAGT TCTATGCGGA GTTTGAAAGT 
TTAATGGACC CTTCAAGGAA CCACAGGGCC TACAGGCTGA CAGTAGCTAA GCTGGAACCT 
CCTCTCATCC CCTTCATGCC TTTGCTCATT AAAGATATGA CATTTACTCA TGAGGGGAAC 
AAGACGTTCA TTGACAATCT AGTAAACTTT GAAAAAATGC GCATGATTGC AAATACGGCC 
AGAACAGTGA GATACTACAG GAGCCAACCC TTCAATCCTG ATGCAGCTCA AGCTAATAAG 
AACCATCAGG ATGTCCGGAG TTATGTACGG CAATTAAATG TGATTGACAA CCAGAGAACT 
TTATCACAGA TGTCACACAG ATTAGAGCCT CGTCGACCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( XM_005246246.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005246303.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu35775
Clone ID Related Accession (Same CDS sequence)	XM_005246246.3 , XM_005246246.2 , NM_001375866.1
Accession Version	XM_005246246.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2982bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005246246.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACGTC 
CCTTCAGAGA AGATCCTCAG AGCTGGAAAA ATTTTACGAA ATGCCATTCT CTCTCGAGCA 
CCTCACATGA TAAGAGATAG AAAATACCAC CTAAAGACAT ACAGACAATG CTGTGTGGGA 
ACTGAACTGG TGGACTGGAT GATGCAGCAG ACACCATGTG TTCACTCCCG GACTCAAGCT 
GTTGGCATGT GGCAAGTCCT GTTAGAAGAT GGTGTTCTCA ACCACGTGGA CCAGGAGCAC 
CATTTCCAAG ACAAATATTT ATTCTATCGA TTTCTGGATG ATGAGCACGA GGATGCCCCT 
TTGCCTACTG AGGAGGAGAA GAAGGAGTGT GATGAGGAGC TCCAGGACAC CATGCTGCTG 
CTGTCACAGA TGGGCCCCGA CGCCCACATG AGGATGATCC TTCGCAAACC ACCTGGCCAG 
AGGACTGTGG ATGACCTAGA GATTATCTAT GAGGAGCTTC TTCATATTAA AGCCTTATCC 
CATCTTTCTA CCACAGTGAA ACGAGAGTTA GCAGGTGTTC TCATTTTTGA GTCTCACGCC 
AAAGGAGGGA CTGTGTTGTT TAACCAGGGG GAAGAAGGTA CCTCCTGGTA CATTATTCTA 
AAAGGATCAG TGAATGTAGT CATTTACGGC AAGGGTGTGG TCTGCACCCT GCATGAAGGA 
GATGACTTCG GCAAGTTAGC ACTAGTGAAT GATGCCCCAC GAGCTGCCTC TATCGTCTTA 
CGAGAAGATA ACTGCCATTT CTTAAGAGTA GACAAGGAGG ATTTCAACCG GATCCTAAGG 
GACGTGGAGG CGAATACAGT CAGACTTAAA GAACATGACC AAGATGTCTT GGTGCTGGAG 
AAGGTCCCAG CAGGGAACAG AGCTTCTAAT CAAGGAAACT CACAGCCTCA GCAAAAGTAT 
ACTGTGATGT CAGGAACACC TGAAAAAATT TTAGAGCATT TTCTAGAAAC AATACGCCTT 
GAGGCAACTT TAAATGAAGC AACAGATTCT GTTTTAAATG ACTTTATTAT GATGCACTGT 
GTTTTTATGC CAAATACCCA GCTTTGCCCG GCACTGGTGG CCCACTACCA CGCACAGCCT 
TCACAAGGTA CAGAACAGGA GAAAATGGAT TATGCCCTCA ACAATAAGAG GCGAGTCATC 
CGCCTGGTTC TACAGTGGGC TGCCATGTAT GGAGACCTCC TGCAAGAGGA TGACGTGTCT 
ATGGCCTTCC TGGAGGAGTT TTATGTATCT GTATCAGATG ATGCCCGGAT GATTGCTGCC 
CTCAAGGAGC AACTGCCAGA GTTGGAGAAG ATTGTCAAGC AAATCTCAGA AGATGCAAAG 
GCACCACAAA AGAAGCACAA GGTTCTTTTG CAACAGTTCA ATACGGGCGA TGAGAGAGCC 
CAGAAGCGCC AGCCTATCCG CGGCTCTGAT GAAGTTCTGT TTAAGGTCTA TTGCATGGAC 
CACACCTACA CAACCATTCG GGTGCCAGTG GCCACTTCGG TGAAGGAAGT CATCAGTGCA 
GTTGCCGACA AGCTGGGCTC CGGGGAGGGC CTGATCATAG TCAAGATGAG TTCCGGAGGA 
GAAAAGGTGG TGCTCAAACC TAATGATGTT TCAGTATTTA CGACGCTCAC CATTAATGGA 
CGCCTGTTTG CTTGCCCGCG AGAGCAATTC GATTCACTGA CTCCCTTACC AGAACAGGAA 
GGCCCAACTG TTGGAACAGT GGGAACTTTT GAACTGATGA GCTCCAAAGA TTTAGCATAC 
CAGATGACAA TTTATGATTG GGAACTCTTC AACTGCGTGC ATGAGCTGGA GCTAATCTAT 
CACACATTTG GAAGGCATAA TTTTAAAAAG ACCACAGCAA ACTTGGATTT GTTCCTGAGG 
AGATTTAATG AAATTCAGTT TTGGGTCGTC ACTGAGATCT GCCTTTGTTC TCAGCTCAGC 
AAGCGTGTTC AGCTATTAAA AAAATTTATT AAGATAGCAG CCCACTGTAA GGAGTATAAA 
AATCTGAATT CCTTTTTTGC CATCGTCATG GGACTAAGTA ACGTTGCTGT GAGCCGCTTG 
GCACTAACGT GGGAGAAACT GCCAAGCAAG TTCAAGAAGT TCTATGCGGA GTTTGAAAGT 
TTAATGGACC CTTCAAGGAA CCACAGGGCC TACAGGCTGA CAGTAGCTAA GCTGGAACCT 
CCTCTCATCC CCTTCATGCC TTTGCTCATT AAAGATATGA CATTTACTCA TGAGGGGAAC 
AAGACGTTCA TTGACAATCT AGTAAACTTT GAAAAAATGC GCATGATTGC AAATACGGCC 
AGAACAGTGA GATACTACAG GAGCCAACCC TTCAATCCTG ATGCAGCTCA AGCTAATAAG 
AACCATCAGG ATGTCCGGAG TTATGTACGG CAATTAAATG TGATTGACAA CCAGAGAACT 
TTATCACAGA TGTCACACAG ATTAGAGCCT CGTCGACCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005246303.1
CDS	55..3036
Translation	MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	XM_005246246.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005246246.2

ORF Insert Sequence:

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACGTC 
CCTTCAGAGA AGATCCTCAG AGCTGGAAAA ATTTTACGAA ATGCCATTCT CTCTCGAGCA 
CCTCACATGA TAAGAGATAG AAAATACCAC CTAAAGACAT ACAGACAATG CTGTGTGGGA 
ACTGAACTGG TGGACTGGAT GATGCAGCAG ACACCATGTG TTCACTCCCG GACTCAAGCT 
GTTGGCATGT GGCAAGTCCT GTTAGAAGAT GGTGTTCTCA ACCACGTGGA CCAGGAGCAC 
CATTTCCAAG ACAAATATTT ATTCTATCGA TTTCTGGATG ATGAGCACGA GGATGCCCCT 
TTGCCTACTG AGGAGGAGAA GAAGGAGTGT GATGAGGAGC TCCAGGACAC CATGCTGCTG 
CTGTCACAGA TGGGCCCCGA CGCCCACATG AGGATGATCC TTCGCAAACC ACCTGGCCAG 
AGGACTGTGG ATGACCTAGA GATTATCTAT GAGGAGCTTC TTCATATTAA AGCCTTATCC 
CATCTTTCTA CCACAGTGAA ACGAGAGTTA GCAGGTGTTC TCATTTTTGA GTCTCACGCC 
AAAGGAGGGA CTGTGTTGTT TAACCAGGGG GAAGAAGGTA CCTCCTGGTA CATTATTCTA 
AAAGGATCAG TGAATGTAGT CATTTACGGC AAGGGTGTGG TCTGCACCCT GCATGAAGGA 
GATGACTTCG GCAAGTTAGC ACTAGTGAAT GATGCCCCAC GAGCTGCCTC TATCGTCTTA 
CGAGAAGATA ACTGCCATTT CTTAAGAGTA GACAAGGAGG ATTTCAACCG GATCCTAAGG 
GACGTGGAGG CGAATACAGT CAGACTTAAA GAACATGACC AAGATGTCTT GGTGCTGGAG 
AAGGTCCCAG CAGGGAACAG AGCTTCTAAT CAAGGAAACT CACAGCCTCA GCAAAAGTAT 
ACTGTGATGT CAGGAACACC TGAAAAAATT TTAGAGCATT TTCTAGAAAC AATACGCCTT 
GAGGCAACTT TAAATGAAGC AACAGATTCT GTTTTAAATG ACTTTATTAT GATGCACTGT 
GTTTTTATGC CAAATACCCA GCTTTGCCCG GCACTGGTGG CCCACTACCA CGCACAGCCT 
TCACAAGGTA CAGAACAGGA GAAAATGGAT TATGCCCTCA ACAATAAGAG GCGAGTCATC 
CGCCTGGTTC TACAGTGGGC TGCCATGTAT GGAGACCTCC TGCAAGAGGA TGACGTGTCT 
ATGGCCTTCC TGGAGGAGTT TTATGTATCT GTATCAGATG ATGCCCGGAT GATTGCTGCC 
CTCAAGGAGC AACTGCCAGA GTTGGAGAAG ATTGTCAAGC AAATCTCAGA AGATGCAAAG 
GCACCACAAA AGAAGCACAA GGTTCTTTTG CAACAGTTCA ATACGGGCGA TGAGAGAGCC 
CAGAAGCGCC AGCCTATCCG CGGCTCTGAT GAAGTTCTGT TTAAGGTCTA TTGCATGGAC 
CACACCTACA CAACCATTCG GGTGCCAGTG GCCACTTCGG TGAAGGAAGT CATCAGTGCA 
GTTGCCGACA AGCTGGGCTC CGGGGAGGGC CTGATCATAG TCAAGATGAG TTCCGGAGGA 
GAAAAGGTGG TGCTCAAACC TAATGATGTT TCAGTATTTA CGACGCTCAC CATTAATGGA 
CGCCTGTTTG CTTGCCCGCG AGAGCAATTC GATTCACTGA CTCCCTTACC AGAACAGGAA 
GGCCCAACTG TTGGAACAGT GGGAACTTTT GAACTGATGA GCTCCAAAGA TTTAGCATAC 
CAGATGACAA TTTATGATTG GGAACTCTTC AACTGCGTGC ATGAGCTGGA GCTAATCTAT 
CACACATTTG GAAGGCATAA TTTTAAAAAG ACCACAGCAA ACTTGGATTT GTTCCTGAGG 
AGATTTAATG AAATTCAGTT TTGGGTCGTC ACTGAGATCT GCCTTTGTTC TCAGCTCAGC 
AAGCGTGTTC AGCTATTAAA AAAATTTATT AAGATAGCAG CCCACTGTAA GGAGTATAAA 
AATCTGAATT CCTTTTTTGC CATCGTCATG GGACTAAGTA ACGTTGCTGT GAGCCGCTTG 
GCACTAACGT GGGAGAAACT GCCAAGCAAG TTCAAGAAGT TCTATGCGGA GTTTGAAAGT 
TTAATGGACC CTTCAAGGAA CCACAGGGCC TACAGGCTGA CAGTAGCTAA GCTGGAACCT 
CCTCTCATCC CCTTCATGCC TTTGCTCATT AAAGATATGA CATTTACTCA TGAGGGGAAC 
AAGACGTTCA TTGACAATCT AGTAAACTTT GAAAAAATGC GCATGATTGC AAATACGGCC 
AGAACAGTGA GATACTACAG GAGCCAACCC TTCAATCCTG ATGCAGCTCA AGCTAATAAG 
AACCATCAGG ATGTCCGGAG TTATGTACGG CAATTAAATG TGATTGACAA CCAGAGAACT 
TTATCACAGA TGTCACACAG ATTAGAGCCT CGTCGACCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( XM_011510505.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011508807.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu64677
Clone ID Related Accession (Same CDS sequence)	XM_011510505.2 , XM_011510505.3
Accession Version	XM_011510505.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2646bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011510505.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG AAGGACTTCA 
AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT CCTTATGGTG 
TTATGGAAAC GGGCTCTAAC AATGACAACA CCTCTCATTG AACCTCACGT TCCTCTTCGT 
CCTGCTAACA CCATTACCAA GGTCCCTTCA GAGAAGATCC TCAGAGCTGG AAAAATTTTA 
CGAAATGCCA TTCTCTCTCG AGCACCTCAC ATGATAAGAG ATAGAAAATA CCACCTAAAG 
ACATACAGAC AATGCTGTGT GGGAACTGAA CTGGTGGACT GGATGATGCA GCAGACACCA 
TGTGTTCACT CCCGGACTCA AGCTGTTGGC ATGTGGCAAG TCCTGTTAGA AGATGGTGTT 
CTCAACCACG TGGACCAGGA GCACCATTTC CAAGACAAAT ATTTATTCTA TCGATTTCTG 
GATGATGAGC ACGAGGATGC CCCTTTGCCT ACTGAGGAGG AGAAGAAGGA GTGTGATGAG 
GAGCTCCAGG ACACCATGCT GCTGCTGTCA CAGATGGGCC CCGACGCCCA CATGAGGATG 
ATCCTTCGCA AACCACCTGG CCAGAGGACT GTGGATGACC TAGAGATTAT CTATGAGGAG 
CTTCTTCATA TTAAAGCCTT ATCCCATCTT TCTACCACAG TGAAACGAGA GTTAGCAGGT 
GTTCTCATTT TTGAGTCTCA CGCCAAAGGA GGGACTGTGT TGTTTAACCA GGGGGAAGAA 
GGTACCTCCT GGTACATTAT TCTAAAAGGA TCAGTGAATG TAGTCATTTA CGGCAAGGGT 
GTGGTCTGCA CCCTGCATGA AGGAGATGAC TTCGGCAAGT TAGCACTAGT GAATGATGCC 
CCACGAGCTG CCTCTATCGT CTTACGAGAA GATAACTGCC ATTTCTTAAG AGTAGACAAG 
GAGGATTTCA ACCGGATCCT AAGGGACGTG GAGGCGAATA CAGTCAGACT TAAAGAACAT 
GACCAAGATG TCTTGGTGCT GGAGAAGGTC CCAGCAGGGA ACAGAGCTTC TAATCAAGGA 
AACTCACAGC CTCAGCAAAA GTATACTGTG ATGTCAGGAA CACCTGAAAA AATTTTAGAG 
CATTTTCTAG AAACAATACG CCTTGAGGCA ACTTTAAATG AAGCAACAGA TTCTGTTTTA 
AATGACTTTA TTATGATGCA CTGTGTTTTT ATGCCAAATA CCCAGCTTTG CCCGGCACTG 
GTGGCCCACT ACCACGCACA GCCTTCACAA GGTACAGAAC AGGAGAAAAT GGATTATGCC 
CTCAACAATA AGAGGCGAGT CATCCGCCTG GTTCTACAGT GGGCTGCCAT GTATGGAGAC 
CTCCTGCAAG AGGATGACGT GTCTATGGCC TTCCTGGAGG AGTTTTATGT ATCTGTATCA 
GATGATGCCC GGATGATTGC TGCCCTCAAG GAGCAACTGC CAGAGTTGGA GAAGATTGTC 
AAGCAAATCT CAGAAGATGC AAAGGCACCA CAAAAGAAGC ACAAGGTTCT TTTGCAACAG 
TTCAATACGG GCGATGAGAG AGCCCAGAAG CGCCAGCCTA TCCGCGGCTC TGATGAAGTT 
CTGTTTAAGG TCTATTGCAT GGACCACACC TACACAACCA TTCGGGTGCC AGTGGCCACT 
TCGGTGAAGG AAGTCATCAG TGCAGTTGCC GACAAGCTGG GCTCCGGGGA GGGCCTGATC 
ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG GTGGTGCTCA AACCTAATGA TGTTTCAGTA 
TTTACGACGC TCACCATTAA TGGACGCCTG TTTGCTTGCC CGCGAGAGCA ATTCGATTCA 
CTGACTCCCT TACCAGAACA GGAAGGCCCA ACTGTTGGAA CAGTGGGAAC TTTTGAACTG 
ATGAGCTCCA AAGATTTAGC ATACCAGATG ACAATTTATG ATTGGGAACT CTTCAACTGC 
GTGCATGAGC TGGAGCTAAT CTATCACACA TTTGGAAGGC ATAATTTTAA AAAGACCACA 
GCAAACTTGG ATTTGTTCCT GAGGAGATTT AATGAAATTC AGTTTTGGGT CGTCACTGAG 
ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT GTTCAGCTAT TAAAAAAATT TATTAAGATA 
GCAGCCCACT GTAAGGAGTA TAAAAATCTG AATTCCTTTT TTGCCATCGT CATGGGACTA 
AGTAACGTTG CTGTGAGCCG CTTGGCACTA ACGTGGGAGA AACTGCCAAG CAAGTTCAAG 
AAGTTCTATG CGGAGTTTGA AAGTTTAATG GACCCTTCAA GGAACCACAG GGCCTACAGG 
CTGACAGTAG CTAAGCTGGA ACCTCCTCTC ATCCCCTTCA TGCCTTTGCT CATTAAAGAT 
ATGACATTTA CTCATGAGGG GAACAAGACG TTCATTGACA ATCTAGTAAA CTTTGAAAAA 
ATGCGCATGA TTGCAAATAC GGCCAGAACA GTGAGATACT ACAGGAGCCA ACCCTTCAAT 
CCTGATGCAG CTCAAGCTAA TAAGAACCAT CAGGATGTCC GGAGTTATGT ACGGCAATTA 
AATGTGATTG ACAACCAGAG AACTTTATCA CAGATGTCAC ACAGATTAGA GCCTCGTCGA 
CCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011508807.1
CDS	425..3070
Translation	MQPSLPGRAVNCSASSRRTSRHYGRNIDSIWQDFWLLLMVLWKRALTMTTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	XM_011510505.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011510505.2

ORF Insert Sequence:

ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG AAGGACTTCA 
AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT CCTTATGGTG 
TTATGGAAAC GGGCTCTAAC AATGACAACA CCTCTCATTG AACCTCACGT TCCTCTTCGT 
CCTGCTAACA CCATTACCAA GGTCCCTTCA GAGAAGATCC TCAGAGCTGG AAAAATTTTA 
CGAAATGCCA TTCTCTCTCG AGCACCTCAC ATGATAAGAG ATAGAAAATA CCACCTAAAG 
ACATACAGAC AATGCTGTGT GGGAACTGAA CTGGTGGACT GGATGATGCA GCAGACACCA 
TGTGTTCACT CCCGGACTCA AGCTGTTGGC ATGTGGCAAG TCCTGTTAGA AGATGGTGTT 
CTCAACCACG TGGACCAGGA GCACCATTTC CAAGACAAAT ATTTATTCTA TCGATTTCTG 
GATGATGAGC ACGAGGATGC CCCTTTGCCT ACTGAGGAGG AGAAGAAGGA GTGTGATGAG 
GAGCTCCAGG ACACCATGCT GCTGCTGTCA CAGATGGGCC CCGACGCCCA CATGAGGATG 
ATCCTTCGCA AACCACCTGG CCAGAGGACT GTGGATGACC TAGAGATTAT CTATGAGGAG 
CTTCTTCATA TTAAAGCCTT ATCCCATCTT TCTACCACAG TGAAACGAGA GTTAGCAGGT 
GTTCTCATTT TTGAGTCTCA CGCCAAAGGA GGGACTGTGT TGTTTAACCA GGGGGAAGAA 
GGTACCTCCT GGTACATTAT TCTAAAAGGA TCAGTGAATG TAGTCATTTA CGGCAAGGGT 
GTGGTCTGCA CCCTGCATGA AGGAGATGAC TTCGGCAAGT TAGCACTAGT GAATGATGCC 
CCACGAGCTG CCTCTATCGT CTTACGAGAA GATAACTGCC ATTTCTTAAG AGTAGACAAG 
GAGGATTTCA ACCGGATCCT AAGGGACGTG GAGGCGAATA CAGTCAGACT TAAAGAACAT 
GACCAAGATG TCTTGGTGCT GGAGAAGGTC CCAGCAGGGA ACAGAGCTTC TAATCAAGGA 
AACTCACAGC CTCAGCAAAA GTATACTGTG ATGTCAGGAA CACCTGAAAA AATTTTAGAG 
CATTTTCTAG AAACAATACG CCTTGAGGCA ACTTTAAATG AAGCAACAGA TTCTGTTTTA 
AATGACTTTA TTATGATGCA CTGTGTTTTT ATGCCAAATA CCCAGCTTTG CCCGGCACTG 
GTGGCCCACT ACCACGCACA GCCTTCACAA GGTACAGAAC AGGAGAAAAT GGATTATGCC 
CTCAACAATA AGAGGCGAGT CATCCGCCTG GTTCTACAGT GGGCTGCCAT GTATGGAGAC 
CTCCTGCAAG AGGATGACGT GTCTATGGCC TTCCTGGAGG AGTTTTATGT ATCTGTATCA 
GATGATGCCC GGATGATTGC TGCCCTCAAG GAGCAACTGC CAGAGTTGGA GAAGATTGTC 
AAGCAAATCT CAGAAGATGC AAAGGCACCA CAAAAGAAGC ACAAGGTTCT TTTGCAACAG 
TTCAATACGG GCGATGAGAG AGCCCAGAAG CGCCAGCCTA TCCGCGGCTC TGATGAAGTT 
CTGTTTAAGG TCTATTGCAT GGACCACACC TACACAACCA TTCGGGTGCC AGTGGCCACT 
TCGGTGAAGG AAGTCATCAG TGCAGTTGCC GACAAGCTGG GCTCCGGGGA GGGCCTGATC 
ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG GTGGTGCTCA AACCTAATGA TGTTTCAGTA 
TTTACGACGC TCACCATTAA TGGACGCCTG TTTGCTTGCC CGCGAGAGCA ATTCGATTCA 
CTGACTCCCT TACCAGAACA GGAAGGCCCA ACTGTTGGAA CAGTGGGAAC TTTTGAACTG 
ATGAGCTCCA AAGATTTAGC ATACCAGATG ACAATTTATG ATTGGGAACT CTTCAACTGC 
GTGCATGAGC TGGAGCTAAT CTATCACACA TTTGGAAGGC ATAATTTTAA AAAGACCACA 
GCAAACTTGG ATTTGTTCCT GAGGAGATTT AATGAAATTC AGTTTTGGGT CGTCACTGAG 
ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT GTTCAGCTAT TAAAAAAATT TATTAAGATA 
GCAGCCCACT GTAAGGAGTA TAAAAATCTG AATTCCTTTT TTGCCATCGT CATGGGACTA 
AGTAACGTTG CTGTGAGCCG CTTGGCACTA ACGTGGGAGA AACTGCCAAG CAAGTTCAAG 
AAGTTCTATG CGGAGTTTGA AAGTTTAATG GACCCTTCAA GGAACCACAG GGCCTACAGG 
CTGACAGTAG CTAAGCTGGA ACCTCCTCTC ATCCCCTTCA TGCCTTTGCT CATTAAAGAT 
ATGACATTTA CTCATGAGGG GAACAAGACG TTCATTGACA ATCTAGTAAA CTTTGAAAAA 
ATGCGCATGA TTGCAAATAC GGCCAGAACA GTGAGATACT ACAGGAGCCA ACCCTTCAAT 
CCTGATGCAG CTCAAGCTAA TAAGAACCAT CAGGATGTCC GGAGTTATGT ACGGCAATTA 
AATGTGATTG ACAACCAGAG AACTTTATCA CAGATGTCAC ACAGATTAGA GCCTCGTCGA 
CCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( XM_011510505.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011508807.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu64677
Clone ID Related Accession (Same CDS sequence)	XM_011510505.2 , XM_011510505.3
Accession Version	XM_011510505.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2646bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011510505.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG AAGGACTTCA 
AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT CCTTATGGTG 
TTATGGAAAC GGGCTCTAAC AATGACAACA CCTCTCATTG AACCTCACGT TCCTCTTCGT 
CCTGCTAACA CCATTACCAA GGTCCCTTCA GAGAAGATCC TCAGAGCTGG AAAAATTTTA 
CGAAATGCCA TTCTCTCTCG AGCACCTCAC ATGATAAGAG ATAGAAAATA CCACCTAAAG 
ACATACAGAC AATGCTGTGT GGGAACTGAA CTGGTGGACT GGATGATGCA GCAGACACCA 
TGTGTTCACT CCCGGACTCA AGCTGTTGGC ATGTGGCAAG TCCTGTTAGA AGATGGTGTT 
CTCAACCACG TGGACCAGGA GCACCATTTC CAAGACAAAT ATTTATTCTA TCGATTTCTG 
GATGATGAGC ACGAGGATGC CCCTTTGCCT ACTGAGGAGG AGAAGAAGGA GTGTGATGAG 
GAGCTCCAGG ACACCATGCT GCTGCTGTCA CAGATGGGCC CCGACGCCCA CATGAGGATG 
ATCCTTCGCA AACCACCTGG CCAGAGGACT GTGGATGACC TAGAGATTAT CTATGAGGAG 
CTTCTTCATA TTAAAGCCTT ATCCCATCTT TCTACCACAG TGAAACGAGA GTTAGCAGGT 
GTTCTCATTT TTGAGTCTCA CGCCAAAGGA GGGACTGTGT TGTTTAACCA GGGGGAAGAA 
GGTACCTCCT GGTACATTAT TCTAAAAGGA TCAGTGAATG TAGTCATTTA CGGCAAGGGT 
GTGGTCTGCA CCCTGCATGA AGGAGATGAC TTCGGCAAGT TAGCACTAGT GAATGATGCC 
CCACGAGCTG CCTCTATCGT CTTACGAGAA GATAACTGCC ATTTCTTAAG AGTAGACAAG 
GAGGATTTCA ACCGGATCCT AAGGGACGTG GAGGCGAATA CAGTCAGACT TAAAGAACAT 
GACCAAGATG TCTTGGTGCT GGAGAAGGTC CCAGCAGGGA ACAGAGCTTC TAATCAAGGA 
AACTCACAGC CTCAGCAAAA GTATACTGTG ATGTCAGGAA CACCTGAAAA AATTTTAGAG 
CATTTTCTAG AAACAATACG CCTTGAGGCA ACTTTAAATG AAGCAACAGA TTCTGTTTTA 
AATGACTTTA TTATGATGCA CTGTGTTTTT ATGCCAAATA CCCAGCTTTG CCCGGCACTG 
GTGGCCCACT ACCACGCACA GCCTTCACAA GGTACAGAAC AGGAGAAAAT GGATTATGCC 
CTCAACAATA AGAGGCGAGT CATCCGCCTG GTTCTACAGT GGGCTGCCAT GTATGGAGAC 
CTCCTGCAAG AGGATGACGT GTCTATGGCC TTCCTGGAGG AGTTTTATGT ATCTGTATCA 
GATGATGCCC GGATGATTGC TGCCCTCAAG GAGCAACTGC CAGAGTTGGA GAAGATTGTC 
AAGCAAATCT CAGAAGATGC AAAGGCACCA CAAAAGAAGC ACAAGGTTCT TTTGCAACAG 
TTCAATACGG GCGATGAGAG AGCCCAGAAG CGCCAGCCTA TCCGCGGCTC TGATGAAGTT 
CTGTTTAAGG TCTATTGCAT GGACCACACC TACACAACCA TTCGGGTGCC AGTGGCCACT 
TCGGTGAAGG AAGTCATCAG TGCAGTTGCC GACAAGCTGG GCTCCGGGGA GGGCCTGATC 
ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG GTGGTGCTCA AACCTAATGA TGTTTCAGTA 
TTTACGACGC TCACCATTAA TGGACGCCTG TTTGCTTGCC CGCGAGAGCA ATTCGATTCA 
CTGACTCCCT TACCAGAACA GGAAGGCCCA ACTGTTGGAA CAGTGGGAAC TTTTGAACTG 
ATGAGCTCCA AAGATTTAGC ATACCAGATG ACAATTTATG ATTGGGAACT CTTCAACTGC 
GTGCATGAGC TGGAGCTAAT CTATCACACA TTTGGAAGGC ATAATTTTAA AAAGACCACA 
GCAAACTTGG ATTTGTTCCT GAGGAGATTT AATGAAATTC AGTTTTGGGT CGTCACTGAG 
ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT GTTCAGCTAT TAAAAAAATT TATTAAGATA 
GCAGCCCACT GTAAGGAGTA TAAAAATCTG AATTCCTTTT TTGCCATCGT CATGGGACTA 
AGTAACGTTG CTGTGAGCCG CTTGGCACTA ACGTGGGAGA AACTGCCAAG CAAGTTCAAG 
AAGTTCTATG CGGAGTTTGA AAGTTTAATG GACCCTTCAA GGAACCACAG GGCCTACAGG 
CTGACAGTAG CTAAGCTGGA ACCTCCTCTC ATCCCCTTCA TGCCTTTGCT CATTAAAGAT 
ATGACATTTA CTCATGAGGG GAACAAGACG TTCATTGACA ATCTAGTAAA CTTTGAAAAA 
ATGCGCATGA TTGCAAATAC GGCCAGAACA GTGAGATACT ACAGGAGCCA ACCCTTCAAT 
CCTGATGCAG CTCAAGCTAA TAAGAACCAT CAGGATGTCC GGAGTTATGT ACGGCAATTA 
AATGTGATTG ACAACCAGAG AACTTTATCA CAGATGTCAC ACAGATTAGA GCCTCGTCGA 
CCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011508807.1
CDS	436..3081
Translation	MQPSLPGRAVNCSASSRRTSRHYGRNIDSIWQDFWLLLMVLWKRALTMTTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	XM_011510505.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011510505.3

ORF Insert Sequence:

ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG AAGGACTTCA 
AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT CCTTATGGTG 
TTATGGAAAC GGGCTCTAAC AATGACAACA CCTCTCATTG AACCTCACGT TCCTCTTCGT 
CCTGCTAACA CCATTACCAA GGTCCCTTCA GAGAAGATCC TCAGAGCTGG AAAAATTTTA 
CGAAATGCCA TTCTCTCTCG AGCACCTCAC ATGATAAGAG ATAGAAAATA CCACCTAAAG 
ACATACAGAC AATGCTGTGT GGGAACTGAA CTGGTGGACT GGATGATGCA GCAGACACCA 
TGTGTTCACT CCCGGACTCA AGCTGTTGGC ATGTGGCAAG TCCTGTTAGA AGATGGTGTT 
CTCAACCACG TGGACCAGGA GCACCATTTC CAAGACAAAT ATTTATTCTA TCGATTTCTG 
GATGATGAGC ACGAGGATGC CCCTTTGCCT ACTGAGGAGG AGAAGAAGGA GTGTGATGAG 
GAGCTCCAGG ACACCATGCT GCTGCTGTCA CAGATGGGCC CCGACGCCCA CATGAGGATG 
ATCCTTCGCA AACCACCTGG CCAGAGGACT GTGGATGACC TAGAGATTAT CTATGAGGAG 
CTTCTTCATA TTAAAGCCTT ATCCCATCTT TCTACCACAG TGAAACGAGA GTTAGCAGGT 
GTTCTCATTT TTGAGTCTCA CGCCAAAGGA GGGACTGTGT TGTTTAACCA GGGGGAAGAA 
GGTACCTCCT GGTACATTAT TCTAAAAGGA TCAGTGAATG TAGTCATTTA CGGCAAGGGT 
GTGGTCTGCA CCCTGCATGA AGGAGATGAC TTCGGCAAGT TAGCACTAGT GAATGATGCC 
CCACGAGCTG CCTCTATCGT CTTACGAGAA GATAACTGCC ATTTCTTAAG AGTAGACAAG 
GAGGATTTCA ACCGGATCCT AAGGGACGTG GAGGCGAATA CAGTCAGACT TAAAGAACAT 
GACCAAGATG TCTTGGTGCT GGAGAAGGTC CCAGCAGGGA ACAGAGCTTC TAATCAAGGA 
AACTCACAGC CTCAGCAAAA GTATACTGTG ATGTCAGGAA CACCTGAAAA AATTTTAGAG 
CATTTTCTAG AAACAATACG CCTTGAGGCA ACTTTAAATG AAGCAACAGA TTCTGTTTTA 
AATGACTTTA TTATGATGCA CTGTGTTTTT ATGCCAAATA CCCAGCTTTG CCCGGCACTG 
GTGGCCCACT ACCACGCACA GCCTTCACAA GGTACAGAAC AGGAGAAAAT GGATTATGCC 
CTCAACAATA AGAGGCGAGT CATCCGCCTG GTTCTACAGT GGGCTGCCAT GTATGGAGAC 
CTCCTGCAAG AGGATGACGT GTCTATGGCC TTCCTGGAGG AGTTTTATGT ATCTGTATCA 
GATGATGCCC GGATGATTGC TGCCCTCAAG GAGCAACTGC CAGAGTTGGA GAAGATTGTC 
AAGCAAATCT CAGAAGATGC AAAGGCACCA CAAAAGAAGC ACAAGGTTCT TTTGCAACAG 
TTCAATACGG GCGATGAGAG AGCCCAGAAG CGCCAGCCTA TCCGCGGCTC TGATGAAGTT 
CTGTTTAAGG TCTATTGCAT GGACCACACC TACACAACCA TTCGGGTGCC AGTGGCCACT 
TCGGTGAAGG AAGTCATCAG TGCAGTTGCC GACAAGCTGG GCTCCGGGGA GGGCCTGATC 
ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG GTGGTGCTCA AACCTAATGA TGTTTCAGTA 
TTTACGACGC TCACCATTAA TGGACGCCTG TTTGCTTGCC CGCGAGAGCA ATTCGATTCA 
CTGACTCCCT TACCAGAACA GGAAGGCCCA ACTGTTGGAA CAGTGGGAAC TTTTGAACTG 
ATGAGCTCCA AAGATTTAGC ATACCAGATG ACAATTTATG ATTGGGAACT CTTCAACTGC 
GTGCATGAGC TGGAGCTAAT CTATCACACA TTTGGAAGGC ATAATTTTAA AAAGACCACA 
GCAAACTTGG ATTTGTTCCT GAGGAGATTT AATGAAATTC AGTTTTGGGT CGTCACTGAG 
ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT GTTCAGCTAT TAAAAAAATT TATTAAGATA 
GCAGCCCACT GTAAGGAGTA TAAAAATCTG AATTCCTTTT TTGCCATCGT CATGGGACTA 
AGTAACGTTG CTGTGAGCCG CTTGGCACTA ACGTGGGAGA AACTGCCAAG CAAGTTCAAG 
AAGTTCTATG CGGAGTTTGA AAGTTTAATG GACCCTTCAA GGAACCACAG GGCCTACAGG 
CTGACAGTAG CTAAGCTGGA ACCTCCTCTC ATCCCCTTCA TGCCTTTGCT CATTAAAGAT 
ATGACATTTA CTCATGAGGG GAACAAGACG TTCATTGACA ATCTAGTAAA CTTTGAAAAA 
ATGCGCATGA TTGCAAATAC GGCCAGAACA GTGAGATACT ACAGGAGCCA ACCCTTCAAT 
CCTGATGCAG CTCAAGCTAA TAAGAACCAT CAGGATGTCC GGAGTTATGT ACGGCAATTA 
AATGTGATTG ACAACCAGAG AACTTTATCA CAGATGTCAC ACAGATTAGA GCCTCGTCGA 
CCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001375868.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001362797.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 10, mRNA.

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CloneID	OHu109023
Clone ID Related Accession (Same CDS sequence)	NM_001375868.1
Accession Version	NM_001375868.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2889bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform j
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018712.5, AC009484.3, AC104086.6 and AC019046.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.28730.1, SRR1803616.87116.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGAA AAGGTGGTGC TCAAACCTAA TGATGTTTCA 
GTATTTACGA CGCTCACCAT TAATGGACGC CTGTTTGCTT GCCCGCGAGA GCAATTCGAT 
TCACTGACTC CCTTACCAGA ACAGGAAGGC CCAACTGTTG GAACAGTGGG AACTTTTGAA 
CTGATGAGCT CCAAAGATTT AGCATACCAG ATGACAATTT ATGATTGGGA ACTCTTCAAC 
TGCGTGCATG AGCTGGAGCT AATCTATCAC ACATTTGGAA GGCATAATTT TAAAAAGACC 
ACAGCAAACT TGGATTTGTT CCTGAGGAGA TTTAATGAAA TTCAGTTTTG GGTCGTCACT 
GAGATCTGCC TTTGTTCTCA GCTCAGCAAG CGTGTTCAGC TATTAAAAAA ATTTATTAAG 
ATAGCAGCCC ACTGTAAGGA GTATAAAAAT CTGAATTCCT TTTTTGCCAT CGTCATGGGA 
CTAAGTAACG TTGCTGTGAG CCGCTTGGCA CTAACGTGGG AGAAACTGCC AAGCAAGTTC 
AAGAAGTTCT ATGCGGAGTT TGAAAGTTTA ATGGACCCTT CAAGGAACCA CAGGGCCTAC 
AGGCTGACAG TAGCTAAGCT GGAACCTCCT CTCATCCCCT TCATGCCTTT GCTCATTAAA 
GATATGACAT TTACTCATGA GGGGAACAAG ACGTTCATTG ACAATCTAGT AAACTTTGAA 
AAAATGCGCA TGATTGCAAA TACGGCCAGA ACAGTGAGAT ACTACAGGAG CCAACCCTTC 
AATCCTGATG CAGCTCAAGC TAATAAGAAC CATCAGGATG TCCGGAGTTA TGTACGGCAA 
TTAAATGTGA TTGACAACCA GAGAACTTTA TCACAGATGT CACACAGATT AGAGCCTCGT 
CGACCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001362797.1
CDS	140..3028
Translation	MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	NM_001375868.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 10, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001375868.1

ORF Insert Sequence:

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGAA AAGGTGGTGC TCAAACCTAA TGATGTTTCA 
GTATTTACGA CGCTCACCAT TAATGGACGC CTGTTTGCTT GCCCGCGAGA GCAATTCGAT 
TCACTGACTC CCTTACCAGA ACAGGAAGGC CCAACTGTTG GAACAGTGGG AACTTTTGAA 
CTGATGAGCT CCAAAGATTT AGCATACCAG ATGACAATTT ATGATTGGGA ACTCTTCAAC 
TGCGTGCATG AGCTGGAGCT AATCTATCAC ACATTTGGAA GGCATAATTT TAAAAAGACC 
ACAGCAAACT TGGATTTGTT CCTGAGGAGA TTTAATGAAA TTCAGTTTTG GGTCGTCACT 
GAGATCTGCC TTTGTTCTCA GCTCAGCAAG CGTGTTCAGC TATTAAAAAA ATTTATTAAG 
ATAGCAGCCC ACTGTAAGGA GTATAAAAAT CTGAATTCCT TTTTTGCCAT CGTCATGGGA 
CTAAGTAACG TTGCTGTGAG CCGCTTGGCA CTAACGTGGG AGAAACTGCC AAGCAAGTTC 
AAGAAGTTCT ATGCGGAGTT TGAAAGTTTA ATGGACCCTT CAAGGAACCA CAGGGCCTAC 
AGGCTGACAG TAGCTAAGCT GGAACCTCCT CTCATCCCCT TCATGCCTTT GCTCATTAAA 
GATATGACAT TTACTCATGA GGGGAACAAG ACGTTCATTG ACAATCTAGT AAACTTTGAA 
AAAATGCGCA TGATTGCAAA TACGGCCAGA ACAGTGAGAT ACTACAGGAG CCAACCCTTC 
AATCCTGATG CAGCTCAAGC TAATAAGAAC CATCAGGATG TCCGGAGTTA TGTACGGCAA 
TTAAATGTGA TTGACAACCA GAGAACTTTA TCACAGATGT CACACAGATT AGAGCCTCGT 
CGACCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001375872.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001362801.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 14, mRNA.

Price & Availability↑

CloneID	OHu109024
Clone ID Related Accession (Same CDS sequence)	NM_001375872.1
Accession Version	NM_001375872.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2832bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform n
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018712.5, AC009484.3, AC104086.6 and AC019046.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.61449.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG 
GTGGTGCTCA AACCTAATGA TGTTTCAGTA TTTACGACGC TCACCATTAA TGGACGCCTG 
TTTGCTTGCC CGCGAGAGCA ATTCGATTCA CTGACTCCCT TACCAGAACA GGAAGGCCCA 
ACTGTTGGAA CAGTGGGAAC TTTTGAACTG ATGAGCTCCA AAGATTTAGC ATACCAGATG 
ACAATTTATG ATTGGGAACT CTTCAACTGC GTGCATGAGC TGGAGCTAAT CTATCACACA 
TTTGGAAGGC ATAATTTTAA AAAGACCACA GCAAACTTGG ATTTGTTCCT GAGGAGATTT 
AATGAAATTC AGTTTTGGGT CGTCACTGAG ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT 
GTTCAGCTAT TAAAAAAATT TATTAAGATA GCAGCCCACT GTAAGGAGTA TAAAAATCTG 
AATTCCTTTT TTGCCATCGT CATGGGACTA AGTAACGTTG CTGTGAGCCG CTTGGCACTA 
ACGTGGGAGC GCATGATTGC AAATACGGCC AGAACAGTGA GATACTACAG GAGCCAACCC 
TTCAATCCTG ATGCAGCTCA AGCTAATAAG AACCATCAGG ATGTCCGGAG TTATGTACGG 
CAATTAAATG TGATTGACAA CCAGAGAACT TTATCACAGA TGTCACACAG ATTAGAGCCT 
CGTCGACCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001362801.1
CDS	140..2971
Translation	MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWERMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	NM_001375872.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 14, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001375872.1

ORF Insert Sequence:

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG 
GTGGTGCTCA AACCTAATGA TGTTTCAGTA TTTACGACGC TCACCATTAA TGGACGCCTG 
TTTGCTTGCC CGCGAGAGCA ATTCGATTCA CTGACTCCCT TACCAGAACA GGAAGGCCCA 
ACTGTTGGAA CAGTGGGAAC TTTTGAACTG ATGAGCTCCA AAGATTTAGC ATACCAGATG 
ACAATTTATG ATTGGGAACT CTTCAACTGC GTGCATGAGC TGGAGCTAAT CTATCACACA 
TTTGGAAGGC ATAATTTTAA AAAGACCACA GCAAACTTGG ATTTGTTCCT GAGGAGATTT 
AATGAAATTC AGTTTTGGGT CGTCACTGAG ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT 
GTTCAGCTAT TAAAAAAATT TATTAAGATA GCAGCCCACT GTAAGGAGTA TAAAAATCTG 
AATTCCTTTT TTGCCATCGT CATGGGACTA AGTAACGTTG CTGTGAGCCG CTTGGCACTA 
ACGTGGGAGC GCATGATTGC AAATACGGCC AGAACAGTGA GATACTACAG GAGCCAACCC 
TTCAATCCTG ATGCAGCTCA AGCTAATAAG AACCATCAGG ATGTCCGGAG TTATGTACGG 
CAATTAAATG TGATTGACAA CCAGAGAACT TTATCACAGA TGTCACACAG ATTAGAGCCT 
CGTCGACCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001375870.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001362799.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 12, mRNA.

Price & Availability↑

CloneID	OHu109027
Clone ID Related Accession (Same CDS sequence)	NM_001375870.1
Accession Version	NM_001375870.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2850bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform l
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018712.5, AC009484.3, AC104086.6 and AC019046.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.8360.1, SRR1803615.264136.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG 
GTGGTGCTCA AACCTAATGA TGTTTCAGTA TTTACGACGC TCACCATTAA TGGACGCCTG 
TTTGCTTGCC CGCGAGAGCA ATTCGATTCA CTGACTCCCT TACCAGAACA GGAAGGCCCA 
ACTGTTGGAA CAGTGGGAAC TTTTGAACTG ATGAGCTCCA AAGATTTAGC ATACCAGATG 
ACAATTTATG ATTGGGAACT CTTCAACTGC GTGCATGAGC TGGAGCTAAT CTATCACACA 
TTTGGAAGGC ATAATTTTAA AAAGACCACA GCAAACTTGG ATTTGTTCCT GAGGAGATTT 
AATGAAATTC AGTTTTGGGT CGTCACTGAG ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT 
GTTCAGCTAT TAAAAAAATT TATTAAGATA GCAGCCCACT GTAAGGAGTA TAAAAATCTG 
AATTCCTTTT TTGCCATCGT CATGGGACTA AGTAACGTTG CTGTGAGCCG CTTGGCACTA 
ACGTGGGAGA AACTGCCAAG CAAGTTCAAG AAGTTCTATG CGGAGTTTGA AAGTTTAATG 
GACCCTTCAA GGAACCACAG GGCCTACAGG CTGACAGTAG CTAAGCTGGA ACCTCCTCTC 
ATCCCCTTCA TGCCTTTGCT CATTAAAGCG CATGATTGCA AATACGGCCA GAACAGTGAG 
ATACTACAGG AGCCAACCCT TCAATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001362799.1
CDS	140..2989
Translation	MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKAHDCKYGQNSEILQEPTLQS

Target ORF information:

RefSeq Version	NM_001375870.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 12, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001375870.1

ORF Insert Sequence:

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG 
GTGGTGCTCA AACCTAATGA TGTTTCAGTA TTTACGACGC TCACCATTAA TGGACGCCTG 
TTTGCTTGCC CGCGAGAGCA ATTCGATTCA CTGACTCCCT TACCAGAACA GGAAGGCCCA 
ACTGTTGGAA CAGTGGGAAC TTTTGAACTG ATGAGCTCCA AAGATTTAGC ATACCAGATG 
ACAATTTATG ATTGGGAACT CTTCAACTGC GTGCATGAGC TGGAGCTAAT CTATCACACA 
TTTGGAAGGC ATAATTTTAA AAAGACCACA GCAAACTTGG ATTTGTTCCT GAGGAGATTT 
AATGAAATTC AGTTTTGGGT CGTCACTGAG ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT 
GTTCAGCTAT TAAAAAAATT TATTAAGATA GCAGCCCACT GTAAGGAGTA TAAAAATCTG 
AATTCCTTTT TTGCCATCGT CATGGGACTA AGTAACGTTG CTGTGAGCCG CTTGGCACTA 
ACGTGGGAGA AACTGCCAAG CAAGTTCAAG AAGTTCTATG CGGAGTTTGA AAGTTTAATG 
GACCCTTCAA GGAACCACAG GGCCTACAGG CTGACAGTAG CTAAGCTGGA ACCTCCTCTC 
ATCCCCTTCA TGCCTTTGCT CATTAAAGCG CATGATTGCA AATACGGCCA GAACAGTGAG 
ATACTACAGG AGCCAACCCT TCAATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001375874.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001362803.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 16, mRNA.

Price & Availability↑

CloneID	OHu109028
Clone ID Related Accession (Same CDS sequence)	NM_001375874.1
Accession Version	NM_001375874.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2796bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform p
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018712.5, AC009484.3, AC104086.6 and AC019046.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.47890.1, SRR1803614.116830.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACGTC 
CCTTCAGAGA AGATCCTCAG AGCTGGAAAA ATTTTACGAA ATGCCATTCT CTCTCGAGCA 
CCTCACATGA TAAGAGATAG AAAATACCAC CTAAAGACAT ACAGACAATG CTGTGTGGGA 
ACTGAACTGG TGGACTGGAT GATGCAGCAG ACACCATGTG TTCACTCCCG GACTCAAGCT 
GTTGGCATGT GGCAAGTCCT GTTAGAAGAT GGTGTTCTCA ACCACGTGGA CCAGGAGCAC 
CATTTCCAAG ACAAATATTT ATTCTATCGA TTTCTGGATG ATGAGCACGA GGATGCCCCT 
TTGCCTACTG AGGAGGAGAA GAAGGAGTGT GATGAGGAGC TCCAGGACAC CATGCTGCTG 
CTGTCACAGA TGGGCCCCGA CGCCCACATG AGGATGATCC TTCGCAAACC ACCTGGCCAG 
AGGACTGTGG ATGACCTAGA GATTATCTAT GAGGAGCTTC TTCATATTAA AGCCTTATCC 
CATCTTTCTA CCACAGTGAA ACGAGAGTTA GCAGGTGTTC TCATTTTTGA GTCTCACGCC 
AAAGGAGGGA CTGTGTTGTT TAACCAGGGG GAAGAAGGTA CCTCCTGGTA CATTATTCTA 
AAAGGATCAG TGAATGTAGT CATTTACGGC AAGGGTGTGG TCTGCACCCT GCATGAAGGA 
GATGACTTCG GCAAGTTAGC ACTAGTGAAT GATGCCCCAC GAGCTGCCTC TATCGTCTTA 
CGAGAAGATA ACTGCCATTT CTTAAGAGTA GACAAGGAGG ATTTCAACCG GATCCTAAGG 
GACGTGGAGG CGAATACAGT CAGACTTAAA GAACATGACC AAGATGTCTT GGTGCTGGAG 
AAGGTCCCAG CAGGGAACAG AGCTTCTAAT CAAGGAAACT CACAGCCTCA GCAAAAGTAT 
ACTGTGATGT CAGGAACACC TGAAAAAATT TTAGAGCATT TTCTAGAAAC AATACGCCTT 
GAGGCAACTT TAAATGAAGC AACAGATTCT GTTTTAAATG ACTTTATTAT GATGCACTGT 
GTTTTTATGC CAAATACCCA GCTTTGCCCG GCACTGGTGG CCCACTACCA CGCACAGCCT 
TCACAAGGTA CAGAACAGGA GAAAATGGAT TATGCCCTCA ACAATAAGAG GCGAGTCATC 
CGCCTGGTTC TACAGTGGGC TGCCATGTAT GGAGACCTCC TGCAAGAGGA TGACGTGTCT 
ATGGCCTTCC TGGAGGAGTT TTATGTATCT GTATCAGATG ATGCCCGGAT GATTGCTGCC 
CTCAAGGAGC AACTGCCAGA GTTGGAGAAG ATTGTCAAGC AAATCTCAGA AGATGCAAAG 
GCACCACAAA AGAAGCACAA GGTTCTTTTG CAACAGTTCA ATACGGGCGA TGAGAGAGCC 
CAGAAGCGCC AGCCTATCCG CGGCTCTGAT GAAGTTCTGT TTAAGGTCTA TTGCATGGAC 
CACACCTACA CAACCATTCG GGTGCCAGTG GCCACTTCGG TGAAGGAAGT CATCAGTGCA 
GTTGCCGACA AGCTGGGCTC CGGGGAGGGC CTGATCATAG TCAAGATGAG TTCCGGAGGA 
GAAAAGGTGG TGCTCAAACC TAATGATGTT TCAGTATTTA CGACGCTCAC CATTAATGGA 
CGCCTGTTTG CTTGCCCGCG AGAGCAATTC GATTCACTGA CTCCCTTACC AGAACAGGAA 
GGCCCAACTG TTGGAACAGT GGGAACTTTT GAACTGATGA GCTCCAAAGA TTTAGCATAC 
CAGATGACAA TTTATGATTG GGAACTCTTC AACTGCGTGC ATGAGCTGGA GCTAATCTAT 
CACACATTTG GAAGGCATAA TTTTAAAAAG ACCACAGCAA ACTTGGATTT GTTCCTGAGG 
AGATTTAATG AAATTCAGTT TTGGGTCGTC ACTGAGATCT GCCTTTGTTC TCAGCTCAGC 
AAGCGTGTTC AGCTATTAAA AAAATTTATT AAGATAGCAG CCCACTGTAA GGAGTATAAA 
AATCTGAATT CCTTTTTTGC CATCGTCATG GGACTAAGTA ACGTTGCTGT GAGCCGCTTG 
GCACTAACGT GGGAGAAACT GCCAAGCAAG TTCAAGAAGT TCTATGCGGA GTTTGAAAGT 
TTAATGGACC CTTCAAGGAA CCACAGGGCC TACAGGCTGA CAGTAGCTAA GCTGGAACCT 
CCTCTCATCC CCTTCATGCC TTTGCTCATT AAAGCGCATG ATTGCAAATA CGGCCAGAAC 
AGTGAGATAC TACAGGAGCC AACCCTTCAA TCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001362803.1
CDS	140..2935
Translation	MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKAHDCKYGQNSEILQEPTLQS

Target ORF information:

RefSeq Version	NM_001375874.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 16, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001375874.1

ORF Insert Sequence:

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACGTC 
CCTTCAGAGA AGATCCTCAG AGCTGGAAAA ATTTTACGAA ATGCCATTCT CTCTCGAGCA 
CCTCACATGA TAAGAGATAG AAAATACCAC CTAAAGACAT ACAGACAATG CTGTGTGGGA 
ACTGAACTGG TGGACTGGAT GATGCAGCAG ACACCATGTG TTCACTCCCG GACTCAAGCT 
GTTGGCATGT GGCAAGTCCT GTTAGAAGAT GGTGTTCTCA ACCACGTGGA CCAGGAGCAC 
CATTTCCAAG ACAAATATTT ATTCTATCGA TTTCTGGATG ATGAGCACGA GGATGCCCCT 
TTGCCTACTG AGGAGGAGAA GAAGGAGTGT GATGAGGAGC TCCAGGACAC CATGCTGCTG 
CTGTCACAGA TGGGCCCCGA CGCCCACATG AGGATGATCC TTCGCAAACC ACCTGGCCAG 
AGGACTGTGG ATGACCTAGA GATTATCTAT GAGGAGCTTC TTCATATTAA AGCCTTATCC 
CATCTTTCTA CCACAGTGAA ACGAGAGTTA GCAGGTGTTC TCATTTTTGA GTCTCACGCC 
AAAGGAGGGA CTGTGTTGTT TAACCAGGGG GAAGAAGGTA CCTCCTGGTA CATTATTCTA 
AAAGGATCAG TGAATGTAGT CATTTACGGC AAGGGTGTGG TCTGCACCCT GCATGAAGGA 
GATGACTTCG GCAAGTTAGC ACTAGTGAAT GATGCCCCAC GAGCTGCCTC TATCGTCTTA 
CGAGAAGATA ACTGCCATTT CTTAAGAGTA GACAAGGAGG ATTTCAACCG GATCCTAAGG 
GACGTGGAGG CGAATACAGT CAGACTTAAA GAACATGACC AAGATGTCTT GGTGCTGGAG 
AAGGTCCCAG CAGGGAACAG AGCTTCTAAT CAAGGAAACT CACAGCCTCA GCAAAAGTAT 
ACTGTGATGT CAGGAACACC TGAAAAAATT TTAGAGCATT TTCTAGAAAC AATACGCCTT 
GAGGCAACTT TAAATGAAGC AACAGATTCT GTTTTAAATG ACTTTATTAT GATGCACTGT 
GTTTTTATGC CAAATACCCA GCTTTGCCCG GCACTGGTGG CCCACTACCA CGCACAGCCT 
TCACAAGGTA CAGAACAGGA GAAAATGGAT TATGCCCTCA ACAATAAGAG GCGAGTCATC 
CGCCTGGTTC TACAGTGGGC TGCCATGTAT GGAGACCTCC TGCAAGAGGA TGACGTGTCT 
ATGGCCTTCC TGGAGGAGTT TTATGTATCT GTATCAGATG ATGCCCGGAT GATTGCTGCC 
CTCAAGGAGC AACTGCCAGA GTTGGAGAAG ATTGTCAAGC AAATCTCAGA AGATGCAAAG 
GCACCACAAA AGAAGCACAA GGTTCTTTTG CAACAGTTCA ATACGGGCGA TGAGAGAGCC 
CAGAAGCGCC AGCCTATCCG CGGCTCTGAT GAAGTTCTGT TTAAGGTCTA TTGCATGGAC 
CACACCTACA CAACCATTCG GGTGCCAGTG GCCACTTCGG TGAAGGAAGT CATCAGTGCA 
GTTGCCGACA AGCTGGGCTC CGGGGAGGGC CTGATCATAG TCAAGATGAG TTCCGGAGGA 
GAAAAGGTGG TGCTCAAACC TAATGATGTT TCAGTATTTA CGACGCTCAC CATTAATGGA 
CGCCTGTTTG CTTGCCCGCG AGAGCAATTC GATTCACTGA CTCCCTTACC AGAACAGGAA 
GGCCCAACTG TTGGAACAGT GGGAACTTTT GAACTGATGA GCTCCAAAGA TTTAGCATAC 
CAGATGACAA TTTATGATTG GGAACTCTTC AACTGCGTGC ATGAGCTGGA GCTAATCTAT 
CACACATTTG GAAGGCATAA TTTTAAAAAG ACCACAGCAA ACTTGGATTT GTTCCTGAGG 
AGATTTAATG AAATTCAGTT TTGGGTCGTC ACTGAGATCT GCCTTTGTTC TCAGCTCAGC 
AAGCGTGTTC AGCTATTAAA AAAATTTATT AAGATAGCAG CCCACTGTAA GGAGTATAAA 
AATCTGAATT CCTTTTTTGC CATCGTCATG GGACTAAGTA ACGTTGCTGT GAGCCGCTTG 
GCACTAACGT GGGAGAAACT GCCAAGCAAG TTCAAGAAGT TCTATGCGGA GTTTGAAAGT 
TTAATGGACC CTTCAAGGAA CCACAGGGCC TACAGGCTGA CAGTAGCTAA GCTGGAACCT 
CCTCTCATCC CCTTCATGCC TTTGCTCATT AAAGCGCATG ATTGCAAATA CGGCCAGAAC 
AGTGAGATAC TACAGGAGCC AACCCTTCAA TCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001375869.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001362798.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 11, mRNA.

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CloneID	OHu109029
Clone ID Related Accession (Same CDS sequence)	NM_001375869.1
Accession Version	NM_001375869.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2883bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform k
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018712.5, AC009484.3, AC104086.6 and AC019046.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.76217.1, SRR1803611.229882.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG 
GTGGTGCTCA AACCTAATGA TGTTTCAGTA TTTACGACGC TCACCATTAA TGGACGCCTG 
TTTGCTTGCC CGCGAGAGCA ATTCGATTCA CTGACTCCCT TACCAGAACA GGAAGGCCCA 
ACTGTTGGAA CAGTGGGAAC TTTTGAACTG ATGAGCTCCA AAGATTTAGC ATACCAGATG 
ACAATTTATG ATTGGGAACT CTTCAACTGC GTGCATGAGC TGGAGCTAAT CTATCACACA 
TTTGGAAGGC ATAATTTTAA AAAGACCACA GCAAACTTGG ATTTGTTCCT GAGGAGATTT 
AATGAAATTC AGTTTTGGGT CGTCACTGAG ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT 
GTTCAGCTAT TAAAAAAATT TATTAAGATA GCAGCCCACT GTAAGGAGTA TAAAAATCTG 
AATTCCTTTT TTGCCATCGT CATGGGACTA AGTAACGTTG CTGTGAGCCG CTTGGCACTA 
ACGTGGGAGA AACTGCCAAG CAAGTTCAAG AAGTTCTATG CGGAGTTTGA AAGTTTAATG 
CGCATGATTG CAAATACGGC CAGAACAGTG AGATACTACA GGAGCCAACC CTTCAATCCT 
GATGCAGCTC AAGCTAATAA GAACCATCAG GATGTCCGGA GTTATGTACG GCAATTAAAT 
GTGATTGACA ACCAGAGAAC TTTATCACAG ATGTCACACA GATTAGAGCC TCGTCGACCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001362798.1
CDS	140..3022
Translation	MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	NM_001375869.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 11, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001375869.1

ORF Insert Sequence:

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG 
GTGGTGCTCA AACCTAATGA TGTTTCAGTA TTTACGACGC TCACCATTAA TGGACGCCTG 
TTTGCTTGCC CGCGAGAGCA ATTCGATTCA CTGACTCCCT TACCAGAACA GGAAGGCCCA 
ACTGTTGGAA CAGTGGGAAC TTTTGAACTG ATGAGCTCCA AAGATTTAGC ATACCAGATG 
ACAATTTATG ATTGGGAACT CTTCAACTGC GTGCATGAGC TGGAGCTAAT CTATCACACA 
TTTGGAAGGC ATAATTTTAA AAAGACCACA GCAAACTTGG ATTTGTTCCT GAGGAGATTT 
AATGAAATTC AGTTTTGGGT CGTCACTGAG ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT 
GTTCAGCTAT TAAAAAAATT TATTAAGATA GCAGCCCACT GTAAGGAGTA TAAAAATCTG 
AATTCCTTTT TTGCCATCGT CATGGGACTA AGTAACGTTG CTGTGAGCCG CTTGGCACTA 
ACGTGGGAGA AACTGCCAAG CAAGTTCAAG AAGTTCTATG CGGAGTTTGA AAGTTTAATG 
CGCATGATTG CAAATACGGC CAGAACAGTG AGATACTACA GGAGCCAACC CTTCAATCCT 
GATGCAGCTC AAGCTAATAA GAACCATCAG GATGTCCGGA GTTATGTACG GCAATTAAAT 
GTGATTGACA ACCAGAGAAC TTTATCACAG ATGTCACACA GATTAGAGCC TCGTCGACCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001375871.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001362800.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 13, mRNA.

Price & Availability↑

CloneID	OHu109030
Clone ID Related Accession (Same CDS sequence)	NM_001375871.1
Accession Version	NM_001375871.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2835bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform m
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018712.5, AC009484.3, AC104086.6 and AC019046.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.12033.1, SRR1803617.4977.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACGTC 
CCTTCAGAGA AGATCCTCAG AGCTGGAAAA ATTTTACGAA ATGCCATTCT CTCTCGAGCA 
CCTCACATGA TAAGAGATAG AAAATACCAC CTAAAGACAT ACAGACAATG CTGTGTGGGA 
ACTGAACTGG TGGACTGGAT GATGCAGCAG ACACCATGTG TTCACTCCCG GACTCAAGCT 
GTTGGCATGT GGCAAGTCCT GTTAGAAGAT GGTGTTCTCA ACCACGTGGA CCAGGAGCAC 
CATTTCCAAG ACAAATATTT ATTCTATCGA TTTCTGGATG ATGAGCACGA GGATGCCCCT 
TTGCCTACTG AGGAGGAGAA GAAGGAGTGT GATGAGGAGC TCCAGGACAC CATGCTGCTG 
CTGTCACAGA TGGGCCCCGA CGCCCACATG AGGATGATCC TTCGCAAACC ACCTGGCCAG 
AGGACTGTGG ATGACCTAGA GATTATCTAT GAGGAGCTTC TTCATATTAA AGCCTTATCC 
CATCTTTCTA CCACAGTGAA ACGAGAGTTA GCAGGTGTTC TCATTTTTGA GTCTCACGCC 
AAAGGAGGGA CTGTGTTGTT TAACCAGGGG GAAGAAGGTA CCTCCTGGTA CATTATTCTA 
AAAGGATCAG TGAATGTAGT CATTTACGGC AAGGGTGTGG TCTGCACCCT GCATGAAGGA 
GATGACTTCG GCAAGTTAGC ACTAGTGAAT GATGCCCCAC GAGCTGCCTC TATCGTCTTA 
CGAGAAGATA ACTGCCATTT CTTAAGAGTA GACAAGGAGG ATTTCAACCG GATCCTAAGG 
GACGTGGAGG CGAATACAGT CAGACTTAAA GAACATGACC AAGATGTCTT GGTGCTGGAG 
AAGGTCCCAG CAGGGAACAG AGCTTCTAAT CAAGGAAACT CACAGCCTCA GCAAAAGTAT 
ACTGTGATGT CAGGAACACC TGAAAAAATT TTAGAGCATT TTCTAGAAAC AATACGCCTT 
GAGGCAACTT TAAATGAAGC AACAGATTCT GTTTTAAATG ACTTTATTAT GATGCACTGT 
GTTTTTATGC CAAATACCCA GCTTTGCCCG GCACTGGTGG CCCACTACCA CGCACAGCCT 
TCACAAGGTA CAGAACAGGA GAAAATGGAT TATGCCCTCA ACAATAAGAG GCGAGTCATC 
CGCCTGGTTC TACAGTGGGC TGCCATGTAT GGAGACCTCC TGCAAGAGGA TGACGTGTCT 
ATGGCCTTCC TGGAGGAGTT TTATGTATCT GTATCAGATG ATGCCCGGAT GATTGCTGCC 
CTCAAGGAGC AACTGCCAGA GTTGGAGAAG ATTGTCAAGC AAATCTCAGA AGATGCAAAG 
GCACCACAAA AGAAGCACAA GGTTCTTTTG CAACAGTTCA ATACGGGCGA TGAGAGAGCC 
CAGAAGCGCC AGCCTATCCG CGGCTCTGAT GAAGAAAAGG TGGTGCTCAA ACCTAATGAT 
GTTTCAGTAT TTACGACGCT CACCATTAAT GGACGCCTGT TTGCTTGCCC GCGAGAGCAA 
TTCGATTCAC TGACTCCCTT ACCAGAACAG GAAGGCCCAA CTGTTGGAAC AGTGGGAACT 
TTTGAACTGA TGAGCTCCAA AGATTTAGCA TACCAGATGA CAATTTATGA TTGGGAACTC 
TTCAACTGCG TGCATGAGCT GGAGCTAATC TATCACACAT TTGGAAGGCA TAATTTTAAA 
AAGACCACAG CAAACTTGGA TTTGTTCCTG AGGAGATTTA ATGAAATTCA GTTTTGGGTC 
GTCACTGAGA TCTGCCTTTG TTCTCAGCTC AGCAAGCGTG TTCAGCTATT AAAAAAATTT 
ATTAAGATAG CAGCCCACTG TAAGGAGTAT AAAAATCTGA ATTCCTTTTT TGCCATCGTC 
ATGGGACTAA GTAACGTTGC TGTGAGCCGC TTGGCACTAA CGTGGGAGAA ACTGCCAAGC 
AAGTTCAAGA AGTTCTATGC GGAGTTTGAA AGTTTAATGG ACCCTTCAAG GAACCACAGG 
GCCTACAGGC TGACAGTAGC TAAGCTGGAA CCTCCTCTCA TCCCCTTCAT GCCTTTGCTC 
ATTAAAGATA TGACATTTAC TCATGAGGGG AACAAGACGT TCATTGACAA TCTAGTAAAC 
TTTGAAAAAA TGCGCATGAT TGCAAATACG GCCAGAACAG TGAGATACTA CAGGAGCCAA 
CCCTTCAATC CTGATGCAGC TCAAGCTAAT AAGAACCATC AGGATGTCCG GAGTTATGTA 
CGGCAATTAA ATGTGATTGA CAACCAGAGA ACTTTATCAC AGATGTCACA CAGATTAGAG 
CCTCGTCGAC CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001362800.1
CDS	140..2974
Translation	MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	NM_001375871.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 13, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001375871.1

ORF Insert Sequence:

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACGTC 
CCTTCAGAGA AGATCCTCAG AGCTGGAAAA ATTTTACGAA ATGCCATTCT CTCTCGAGCA 
CCTCACATGA TAAGAGATAG AAAATACCAC CTAAAGACAT ACAGACAATG CTGTGTGGGA 
ACTGAACTGG TGGACTGGAT GATGCAGCAG ACACCATGTG TTCACTCCCG GACTCAAGCT 
GTTGGCATGT GGCAAGTCCT GTTAGAAGAT GGTGTTCTCA ACCACGTGGA CCAGGAGCAC 
CATTTCCAAG ACAAATATTT ATTCTATCGA TTTCTGGATG ATGAGCACGA GGATGCCCCT 
TTGCCTACTG AGGAGGAGAA GAAGGAGTGT GATGAGGAGC TCCAGGACAC CATGCTGCTG 
CTGTCACAGA TGGGCCCCGA CGCCCACATG AGGATGATCC TTCGCAAACC ACCTGGCCAG 
AGGACTGTGG ATGACCTAGA GATTATCTAT GAGGAGCTTC TTCATATTAA AGCCTTATCC 
CATCTTTCTA CCACAGTGAA ACGAGAGTTA GCAGGTGTTC TCATTTTTGA GTCTCACGCC 
AAAGGAGGGA CTGTGTTGTT TAACCAGGGG GAAGAAGGTA CCTCCTGGTA CATTATTCTA 
AAAGGATCAG TGAATGTAGT CATTTACGGC AAGGGTGTGG TCTGCACCCT GCATGAAGGA 
GATGACTTCG GCAAGTTAGC ACTAGTGAAT GATGCCCCAC GAGCTGCCTC TATCGTCTTA 
CGAGAAGATA ACTGCCATTT CTTAAGAGTA GACAAGGAGG ATTTCAACCG GATCCTAAGG 
GACGTGGAGG CGAATACAGT CAGACTTAAA GAACATGACC AAGATGTCTT GGTGCTGGAG 
AAGGTCCCAG CAGGGAACAG AGCTTCTAAT CAAGGAAACT CACAGCCTCA GCAAAAGTAT 
ACTGTGATGT CAGGAACACC TGAAAAAATT TTAGAGCATT TTCTAGAAAC AATACGCCTT 
GAGGCAACTT TAAATGAAGC AACAGATTCT GTTTTAAATG ACTTTATTAT GATGCACTGT 
GTTTTTATGC CAAATACCCA GCTTTGCCCG GCACTGGTGG CCCACTACCA CGCACAGCCT 
TCACAAGGTA CAGAACAGGA GAAAATGGAT TATGCCCTCA ACAATAAGAG GCGAGTCATC 
CGCCTGGTTC TACAGTGGGC TGCCATGTAT GGAGACCTCC TGCAAGAGGA TGACGTGTCT 
ATGGCCTTCC TGGAGGAGTT TTATGTATCT GTATCAGATG ATGCCCGGAT GATTGCTGCC 
CTCAAGGAGC AACTGCCAGA GTTGGAGAAG ATTGTCAAGC AAATCTCAGA AGATGCAAAG 
GCACCACAAA AGAAGCACAA GGTTCTTTTG CAACAGTTCA ATACGGGCGA TGAGAGAGCC 
CAGAAGCGCC AGCCTATCCG CGGCTCTGAT GAAGAAAAGG TGGTGCTCAA ACCTAATGAT 
GTTTCAGTAT TTACGACGCT CACCATTAAT GGACGCCTGT TTGCTTGCCC GCGAGAGCAA 
TTCGATTCAC TGACTCCCTT ACCAGAACAG GAAGGCCCAA CTGTTGGAAC AGTGGGAACT 
TTTGAACTGA TGAGCTCCAA AGATTTAGCA TACCAGATGA CAATTTATGA TTGGGAACTC 
TTCAACTGCG TGCATGAGCT GGAGCTAATC TATCACACAT TTGGAAGGCA TAATTTTAAA 
AAGACCACAG CAAACTTGGA TTTGTTCCTG AGGAGATTTA ATGAAATTCA GTTTTGGGTC 
GTCACTGAGA TCTGCCTTTG TTCTCAGCTC AGCAAGCGTG TTCAGCTATT AAAAAAATTT 
ATTAAGATAG CAGCCCACTG TAAGGAGTAT AAAAATCTGA ATTCCTTTTT TGCCATCGTC 
ATGGGACTAA GTAACGTTGC TGTGAGCCGC TTGGCACTAA CGTGGGAGAA ACTGCCAAGC 
AAGTTCAAGA AGTTCTATGC GGAGTTTGAA AGTTTAATGG ACCCTTCAAG GAACCACAGG 
GCCTACAGGC TGACAGTAGC TAAGCTGGAA CCTCCTCTCA TCCCCTTCAT GCCTTTGCTC 
ATTAAAGATA TGACATTTAC TCATGAGGGG AACAAGACGT TCATTGACAA TCTAGTAAAC 
TTTGAAAAAA TGCGCATGAT TGCAAATACG GCCAGAACAG TGAGATACTA CAGGAGCCAA 
CCCTTCAATC CTGATGCAGC TCAAGCTAAT AAGAACCATC AGGATGTCCG GAGTTATGTA 
CGGCAATTAA ATGTGATTGA CAACCAGAGA ACTTTATCAC AGATGTCACA CAGATTAGAG 
CCTCGTCGAC CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001375867.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001362796.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 9, mRNA.

Price & Availability↑

CloneID	OHu109032
Clone ID Related Accession (Same CDS sequence)	NM_001375867.1
Accession Version	NM_001375867.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2943bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform i
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018712.5, AC009484.3, AC104086.6 and AC019046.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.55442.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGACACCT CTCATTGAAC CTCACGTTCC TCTTCGTCCT 
GCTAACACCA TTACCAAGGT CCCTTCAGAG AAGATCCTCA GAGCTGGAAA AATTTTACGA 
AATGCCATTC TCTCTCGAGC ACCTCACATG ATAAGAGATA GAAAATACCA CCTAAAGACA 
TACAGACAAT GCTGTGTGGG AACTGAACTG GTGGACTGGA TGATGCAGCA GACACCATGT 
GTTCACTCCC GGACTCAAGC TGTTGGCATG TGGCAAGTCC TGTTAGAAGA TGGTGTTCTC 
AACCACGTGG ACCAGGAGCA CCATTTCCAA GACAAATATT TATTCTATCG ATTTCTGGAT 
GATGAGCACG AGGATGCCCC TTTGCCTACT GAGGAGGAGA AGAAGGAGTG TGATGAGGAG 
CTCCAGGACA CCATGCTGCT GCTGTCACAG ATGGGCCCCG ACGCCCACAT GAGGATGATC 
CTTCGCAAAC CACCTGGCCA GAGGACTGTG GATGACCTAG AGATTATCTA TGAGGAGCTT 
CTTCATATTA AAGCCTTATC CCATCTTTCT ACCACAGTGA AACGAGAGTT AGCAGGTGTT 
CTCATTTTTG AGTCTCACGC CAAAGGAGGG ACTGTGTTGT TTAACCAGGG GGAAGAAGGT 
ACCTCCTGGT ACATTATTCT AAAAGGATCA GTGAATGTAG TCATTTACGG CAAGGGTGTG 
GTCTGCACCC TGCATGAAGG AGATGACTTC GGCAAGTTAG CACTAGTGAA TGATGCCCCA 
CGAGCTGCCT CTATCGTCTT ACGAGAAGAT AACTGCCATT TCTTAAGAGT AGACAAGGAG 
GATTTCAACC GGATCCTAAG GGACGTGGAG GCGAATACAG TCAGACTTAA AGAACATGAC 
CAAGATGTCT TGGTGCTGGA GAAGGTCCCA GCAGGGAACA GAGCTTCTAA TCAAGGAAAC 
TCACAGCCTC AGCAAAAGTA TACTGTGATG TCAGGAACAC CTGAAAAAAT TTTAGAGCAT 
TTTCTAGAAA CAATACGCCT TGAGGCAACT TTAAATGAAG CAACAGATTC TGTTTTAAAT 
GACTTTATTA TGATGCACTG TGTTTTTATG CCAAATACCC AGCTTTGCCC GGCACTGGTG 
GCCCACTACC ACGCACAGCC TTCACAAGGT ACAGAACAGG AGAAAATGGA TTATGCCCTC 
AACAATAAGA GGCGAGTCAT CCGCCTGGTT CTACAGTGGG CTGCCATGTA TGGAGACCTC 
CTGCAAGAGG ATGACGTGTC TATGGCCTTC CTGGAGGAGT TTTATGTATC TGTATCAGAT 
GATGCCCGGA TGATTGCTGC CCTCAAGGAG CAACTGCCAG AGTTGGAGAA GATTGTCAAG 
CAAATCTCAG AAGATGCAAA GGCACCACAA AAGAAGCACA AGGTTCTTTT GCAACAGTTC 
AATACGGGCG ATGAGAGAGC CCAGAAGCGC CAGCCTATCC GCGGCTCTGA TGAAGTTCTG 
TTTAAGGTCT ATTGCATGGA CCACACCTAC ACAACCATTC GGGTGCCAGT GGCCACTTCG 
GTGAAGGAAG TCATCAGTGC AGTTGCCGAC AAGCTGGGCT CCGGGGAGGG CCTGATCATA 
GTCAAGATGA GTTCCGGAGG AGAAAAGGTG GTGCTCAAAC CTAATGATGT TTCAGTATTT 
ACGACGCTCA CCATTAATGG ACGCCTGTTT GCTTGCCCGC GAGAGCAATT CGATTCACTG 
ACTCCCTTAC CAGAACAGGA AGGCCCAACT GTTGGAACAG TGGGAACTTT TGAACTGATG 
AGCTCCAAAG ATTTAGCATA CCAGATGACA ATTTATGATT GGGAACTCTT CAACTGCGTG 
CATGAGCTGG AGCTAATCTA TCACACATTT GGAAGGCATA ATTTTAAAAA GACCACAGCA 
AACTTGGATT TGTTCCTGAG GAGATTTAAT GAAATTCAGT TTTGGGTCGT CACTGAGATC 
TGCCTTTGTT CTCAGCTCAG CAAGCGTGTT CAGCTATTAA AAAAATTTAT TAAGATAGCA 
GCCCACTGTA AGGAGTATAA AAATCTGAAT TCCTTTTTTG CCATCGTCAT GGGACTAAGT 
AACGTTGCTG TGAGCCGCTT GGCACTAACG TGGGAGAAAC TGCCAAGCAA GTTCAAGAAG 
TTCTATGCGG AGTTTGAAAG TTTAATGGAC CCTTCAAGGA ACCACAGGGC CTACAGGCTG 
ACAGTAGCTA AGCTGGAACC TCCTCTCATC CCCTTCATGC CTTTGCTCAT TAAAGATATG 
ACATTTACTC ATGAGGGGAA CAAGACGTTC ATTGACAATC TAGTAAACTT TGAAAAAATG 
CGCATGATTG CAAATACGGC CAGAACAGTG AGATACTACA GGAGCCAACC CTTCAATCCT 
GATGCAGCTC AAGCTAATAA GAACCATCAG GATGTCCGGA GTTATGTACG GCAATTAAAT 
GTGATTGACA ACCAGAGAAC TTTATCACAG ATGTCACACA GATTAGAGCC TCGTCGACCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001362796.1
CDS	140..3082
Translation	MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWETPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	NM_001375867.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001375867.1

ORF Insert Sequence:

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGACACCT CTCATTGAAC CTCACGTTCC TCTTCGTCCT 
GCTAACACCA TTACCAAGGT CCCTTCAGAG AAGATCCTCA GAGCTGGAAA AATTTTACGA 
AATGCCATTC TCTCTCGAGC ACCTCACATG ATAAGAGATA GAAAATACCA CCTAAAGACA 
TACAGACAAT GCTGTGTGGG AACTGAACTG GTGGACTGGA TGATGCAGCA GACACCATGT 
GTTCACTCCC GGACTCAAGC TGTTGGCATG TGGCAAGTCC TGTTAGAAGA TGGTGTTCTC 
AACCACGTGG ACCAGGAGCA CCATTTCCAA GACAAATATT TATTCTATCG ATTTCTGGAT 
GATGAGCACG AGGATGCCCC TTTGCCTACT GAGGAGGAGA AGAAGGAGTG TGATGAGGAG 
CTCCAGGACA CCATGCTGCT GCTGTCACAG ATGGGCCCCG ACGCCCACAT GAGGATGATC 
CTTCGCAAAC CACCTGGCCA GAGGACTGTG GATGACCTAG AGATTATCTA TGAGGAGCTT 
CTTCATATTA AAGCCTTATC CCATCTTTCT ACCACAGTGA AACGAGAGTT AGCAGGTGTT 
CTCATTTTTG AGTCTCACGC CAAAGGAGGG ACTGTGTTGT TTAACCAGGG GGAAGAAGGT 
ACCTCCTGGT ACATTATTCT AAAAGGATCA GTGAATGTAG TCATTTACGG CAAGGGTGTG 
GTCTGCACCC TGCATGAAGG AGATGACTTC GGCAAGTTAG CACTAGTGAA TGATGCCCCA 
CGAGCTGCCT CTATCGTCTT ACGAGAAGAT AACTGCCATT TCTTAAGAGT AGACAAGGAG 
GATTTCAACC GGATCCTAAG GGACGTGGAG GCGAATACAG TCAGACTTAA AGAACATGAC 
CAAGATGTCT TGGTGCTGGA GAAGGTCCCA GCAGGGAACA GAGCTTCTAA TCAAGGAAAC 
TCACAGCCTC AGCAAAAGTA TACTGTGATG TCAGGAACAC CTGAAAAAAT TTTAGAGCAT 
TTTCTAGAAA CAATACGCCT TGAGGCAACT TTAAATGAAG CAACAGATTC TGTTTTAAAT 
GACTTTATTA TGATGCACTG TGTTTTTATG CCAAATACCC AGCTTTGCCC GGCACTGGTG 
GCCCACTACC ACGCACAGCC TTCACAAGGT ACAGAACAGG AGAAAATGGA TTATGCCCTC 
AACAATAAGA GGCGAGTCAT CCGCCTGGTT CTACAGTGGG CTGCCATGTA TGGAGACCTC 
CTGCAAGAGG ATGACGTGTC TATGGCCTTC CTGGAGGAGT TTTATGTATC TGTATCAGAT 
GATGCCCGGA TGATTGCTGC CCTCAAGGAG CAACTGCCAG AGTTGGAGAA GATTGTCAAG 
CAAATCTCAG AAGATGCAAA GGCACCACAA AAGAAGCACA AGGTTCTTTT GCAACAGTTC 
AATACGGGCG ATGAGAGAGC CCAGAAGCGC CAGCCTATCC GCGGCTCTGA TGAAGTTCTG 
TTTAAGGTCT ATTGCATGGA CCACACCTAC ACAACCATTC GGGTGCCAGT GGCCACTTCG 
GTGAAGGAAG TCATCAGTGC AGTTGCCGAC AAGCTGGGCT CCGGGGAGGG CCTGATCATA 
GTCAAGATGA GTTCCGGAGG AGAAAAGGTG GTGCTCAAAC CTAATGATGT TTCAGTATTT 
ACGACGCTCA CCATTAATGG ACGCCTGTTT GCTTGCCCGC GAGAGCAATT CGATTCACTG 
ACTCCCTTAC CAGAACAGGA AGGCCCAACT GTTGGAACAG TGGGAACTTT TGAACTGATG 
AGCTCCAAAG ATTTAGCATA CCAGATGACA ATTTATGATT GGGAACTCTT CAACTGCGTG 
CATGAGCTGG AGCTAATCTA TCACACATTT GGAAGGCATA ATTTTAAAAA GACCACAGCA 
AACTTGGATT TGTTCCTGAG GAGATTTAAT GAAATTCAGT TTTGGGTCGT CACTGAGATC 
TGCCTTTGTT CTCAGCTCAG CAAGCGTGTT CAGCTATTAA AAAAATTTAT TAAGATAGCA 
GCCCACTGTA AGGAGTATAA AAATCTGAAT TCCTTTTTTG CCATCGTCAT GGGACTAAGT 
AACGTTGCTG TGAGCCGCTT GGCACTAACG TGGGAGAAAC TGCCAAGCAA GTTCAAGAAG 
TTCTATGCGG AGTTTGAAAG TTTAATGGAC CCTTCAAGGA ACCACAGGGC CTACAGGCTG 
ACAGTAGCTA AGCTGGAACC TCCTCTCATC CCCTTCATGC CTTTGCTCAT TAAAGATATG 
ACATTTACTC ATGAGGGGAA CAAGACGTTC ATTGACAATC TAGTAAACTT TGAAAAAATG 
CGCATGATTG CAAATACGGC CAGAACAGTG AGATACTACA GGAGCCAACC CTTCAATCCT 
GATGCAGCTC AAGCTAATAA GAACCATCAG GATGTCCGGA GTTATGTACG GCAATTAAAT 
GTGATTGACA ACCAGAGAAC TTTATCACAG ATGTCACACA GATTAGAGCC TCGTCGACCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001375873.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001362802.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 15, mRNA.

Price & Availability↑

CloneID	OHu109033
Clone ID Related Accession (Same CDS sequence)	NM_001375873.1
Accession Version	NM_001375873.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2829bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform o
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018712.5, AC009484.3, AC104086.6 and AC019046.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.191354.1, SRR1803617.28479.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACGTC 
CCTTCAGAGA AGATCCTCAG AGCTGGAAAA ATTTTACGAA ATGCCATTCT CTCTCGAGCA 
CCTCACATGA TAAGAGATAG AAAATACCAC CTAAAGACAT ACAGACAATG CTGTGTGGGA 
ACTGAACTGG TGGACTGGAT GATGCAGCAG ACACCATGTG TTCACTCCCG GACTCAAGCT 
GTTGGCATGT GGCAAGTCCT GTTAGAAGAT GGTGTTCTCA ACCACGTGGA CCAGGAGCAC 
CATTTCCAAG ACAAATATTT ATTCTATCGA TTTCTGGATG ATGAGCACGA GGATGCCCCT 
TTGCCTACTG AGGAGGAGAA GAAGGAGTGT GATGAGGAGC TCCAGGACAC CATGCTGCTG 
CTGTCACAGA TGGGCCCCGA CGCCCACATG AGGATGATCC TTCGCAAACC ACCTGGCCAG 
AGGACTGTGG ATGACCTAGA GATTATCTAT GAGGAGCTTC TTCATATTAA AGCCTTATCC 
CATCTTTCTA CCACAGTGAA ACGAGAGTTA GCAGGTGTTC TCATTTTTGA GTCTCACGCC 
AAAGGAGGGA CTGTGTTGTT TAACCAGGGG GAAGAAGGTA CCTCCTGGTA CATTATTCTA 
AAAGGATCAG TGAATGTAGT CATTTACGGC AAGGGTGTGG TCTGCACCCT GCATGAAGGA 
GATGACTTCG GCAAGTTAGC ACTAGTGAAT GATGCCCCAC GAGCTGCCTC TATCGTCTTA 
CGAGAAGATA ACTGCCATTT CTTAAGAGTA GACAAGGAGG ATTTCAACCG GATCCTAAGG 
GACGTGGAGG CGAATACAGT CAGACTTAAA GAACATGACC AAGATGTCTT GGTGCTGGAG 
AAGGTCCCAG CAGGGAACAG AGCTTCTAAT CAAGGAAACT CACAGCCTCA GCAAAAGTAT 
ACTGTGATGT CAGGAACACC TGAAAAAATT TTAGAGCATT TTCTAGAAAC AATACGCCTT 
GAGGCAACTT TAAATGAAGC AACAGATTCT GTTTTAAATG ACTTTATTAT GATGCACTGT 
GTTTTTATGC CAAATACCCA GCTTTGCCCG GCACTGGTGG CCCACTACCA CGCACAGCCT 
TCACAAGGTA CAGAACAGGA GAAAATGGAT TATGCCCTCA ACAATAAGAG GCGAGTCATC 
CGCCTGGTTC TACAGTGGGC TGCCATGTAT GGAGACCTCC TGCAAGAGGA TGACGTGTCT 
ATGGCCTTCC TGGAGGAGTT TTATGTATCT GTATCAGATG ATGCCCGGAT GATTGCTGCC 
CTCAAGGAGC AACTGCCAGA GTTGGAGAAG ATTGTCAAGC AAATCTCAGA AGATGCAAAG 
GCACCACAAA AGAAGCACAA GGTTCTTTTG CAACAGTTCA ATACGGGCGA TGAGAGAGCC 
CAGAAGCGCC AGCCTATCCG CGGCTCTGAT GAAGTTCTGT TTAAGGTCTA TTGCATGGAC 
CACACCTACA CAACCATTCG GGTGCCAGTG GCCACTTCGG TGAAGGAAGT CATCAGTGCA 
GTTGCCGACA AGCTGGGCTC CGGGGAGGGC CTGATCATAG TCAAGATGAG TTCCGGAGGA 
GAAAAGGTGG TGCTCAAACC TAATGATGTT TCAGTATTTA CGACGCTCAC CATTAATGGA 
CGCCTGTTTG CTTGCCCGCG AGAGCAATTC GATTCACTGA CTCCCTTACC AGAACAGGAA 
GGCCCAACTG TTGGAACAGT GGGAACTTTT GAACTGATGA GCTCCAAAGA TTTAGCATAC 
CAGATGACAA TTTATGATTG GGAACTCTTC AACTGCGTGC ATGAGCTGGA GCTAATCTAT 
CACACATTTG GAAGGCATAA TTTTAAAAAG ACCACAGCAA ACTTGGATTT GTTCCTGAGG 
AGATTTAATG AAATTCAGTT TTGGGTCGTC ACTGAGATCT GCCTTTGTTC TCAGCTCAGC 
AAGCGTGTTC AGCTATTAAA AAAATTTATT AAGATAGCAG CCCACTGTAA GGAGTATAAA 
AATCTGAATT CCTTTTTTGC CATCGTCATG GGACTAAGTA ACGTTGCTGT GAGCCGCTTG 
GCACTAACGT GGGAGAAACT GCCAAGCAAG TTCAAGAAGT TCTATGCGGA GTTTGAAAGT 
TTAATGCGCA TGATTGCAAA TACGGCCAGA ACAGTGAGAT ACTACAGGAG CCAACCCTTC 
AATCCTGATG CAGCTCAAGC TAATAAGAAC CATCAGGATG TCCGGAGTTA TGTACGGCAA 
TTAAATGTGA TTGACAACCA GAGAACTTTA TCACAGATGT CACACAGATT AGAGCCTCGT 
CGACCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001362802.1
CDS	140..2968
Translation	MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	NM_001375873.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 15, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001375873.1

ORF Insert Sequence:

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACGTC 
CCTTCAGAGA AGATCCTCAG AGCTGGAAAA ATTTTACGAA ATGCCATTCT CTCTCGAGCA 
CCTCACATGA TAAGAGATAG AAAATACCAC CTAAAGACAT ACAGACAATG CTGTGTGGGA 
ACTGAACTGG TGGACTGGAT GATGCAGCAG ACACCATGTG TTCACTCCCG GACTCAAGCT 
GTTGGCATGT GGCAAGTCCT GTTAGAAGAT GGTGTTCTCA ACCACGTGGA CCAGGAGCAC 
CATTTCCAAG ACAAATATTT ATTCTATCGA TTTCTGGATG ATGAGCACGA GGATGCCCCT 
TTGCCTACTG AGGAGGAGAA GAAGGAGTGT GATGAGGAGC TCCAGGACAC CATGCTGCTG 
CTGTCACAGA TGGGCCCCGA CGCCCACATG AGGATGATCC TTCGCAAACC ACCTGGCCAG 
AGGACTGTGG ATGACCTAGA GATTATCTAT GAGGAGCTTC TTCATATTAA AGCCTTATCC 
CATCTTTCTA CCACAGTGAA ACGAGAGTTA GCAGGTGTTC TCATTTTTGA GTCTCACGCC 
AAAGGAGGGA CTGTGTTGTT TAACCAGGGG GAAGAAGGTA CCTCCTGGTA CATTATTCTA 
AAAGGATCAG TGAATGTAGT CATTTACGGC AAGGGTGTGG TCTGCACCCT GCATGAAGGA 
GATGACTTCG GCAAGTTAGC ACTAGTGAAT GATGCCCCAC GAGCTGCCTC TATCGTCTTA 
CGAGAAGATA ACTGCCATTT CTTAAGAGTA GACAAGGAGG ATTTCAACCG GATCCTAAGG 
GACGTGGAGG CGAATACAGT CAGACTTAAA GAACATGACC AAGATGTCTT GGTGCTGGAG 
AAGGTCCCAG CAGGGAACAG AGCTTCTAAT CAAGGAAACT CACAGCCTCA GCAAAAGTAT 
ACTGTGATGT CAGGAACACC TGAAAAAATT TTAGAGCATT TTCTAGAAAC AATACGCCTT 
GAGGCAACTT TAAATGAAGC AACAGATTCT GTTTTAAATG ACTTTATTAT GATGCACTGT 
GTTTTTATGC CAAATACCCA GCTTTGCCCG GCACTGGTGG CCCACTACCA CGCACAGCCT 
TCACAAGGTA CAGAACAGGA GAAAATGGAT TATGCCCTCA ACAATAAGAG GCGAGTCATC 
CGCCTGGTTC TACAGTGGGC TGCCATGTAT GGAGACCTCC TGCAAGAGGA TGACGTGTCT 
ATGGCCTTCC TGGAGGAGTT TTATGTATCT GTATCAGATG ATGCCCGGAT GATTGCTGCC 
CTCAAGGAGC AACTGCCAGA GTTGGAGAAG ATTGTCAAGC AAATCTCAGA AGATGCAAAG 
GCACCACAAA AGAAGCACAA GGTTCTTTTG CAACAGTTCA ATACGGGCGA TGAGAGAGCC 
CAGAAGCGCC AGCCTATCCG CGGCTCTGAT GAAGTTCTGT TTAAGGTCTA TTGCATGGAC 
CACACCTACA CAACCATTCG GGTGCCAGTG GCCACTTCGG TGAAGGAAGT CATCAGTGCA 
GTTGCCGACA AGCTGGGCTC CGGGGAGGGC CTGATCATAG TCAAGATGAG TTCCGGAGGA 
GAAAAGGTGG TGCTCAAACC TAATGATGTT TCAGTATTTA CGACGCTCAC CATTAATGGA 
CGCCTGTTTG CTTGCCCGCG AGAGCAATTC GATTCACTGA CTCCCTTACC AGAACAGGAA 
GGCCCAACTG TTGGAACAGT GGGAACTTTT GAACTGATGA GCTCCAAAGA TTTAGCATAC 
CAGATGACAA TTTATGATTG GGAACTCTTC AACTGCGTGC ATGAGCTGGA GCTAATCTAT 
CACACATTTG GAAGGCATAA TTTTAAAAAG ACCACAGCAA ACTTGGATTT GTTCCTGAGG 
AGATTTAATG AAATTCAGTT TTGGGTCGTC ACTGAGATCT GCCTTTGTTC TCAGCTCAGC 
AAGCGTGTTC AGCTATTAAA AAAATTTATT AAGATAGCAG CCCACTGTAA GGAGTATAAA 
AATCTGAATT CCTTTTTTGC CATCGTCATG GGACTAAGTA ACGTTGCTGT GAGCCGCTTG 
GCACTAACGT GGGAGAAACT GCCAAGCAAG TTCAAGAAGT TCTATGCGGA GTTTGAAAGT 
TTAATGCGCA TGATTGCAAA TACGGCCAGA ACAGTGAGAT ACTACAGGAG CCAACCCTTC 
AATCCTGATG CAGCTCAAGC TAATAAGAAC CATCAGGATG TCCGGAGTTA TGTACGGCAA 
TTAAATGTGA TTGACAACCA GAGAACTTTA TCACAGATGT CACACAGATT AGAGCCTCGT 
CGACCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001100397.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093867.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu17215
Clone ID Related Accession (Same CDS sequence)	NM_001100397.1 , NM_001100397.2
Accession Version	NM_001100397.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2604bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC009484.3, AC104086.6 and AC019046.4. On Nov 5, 2019 this sequence version replaced NM_001100397.1. Transcript Variant: This variant (2) differs in its 5' UTR, lacks several exons in the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC040183.2, AK304278.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length.

ATGCTCTACA AGAAATATCG ACAGTATATG GCAGGACTTC TGGCTCCTCC TTATGGTGTT 
ATGGAAACGG GCTCTAACAA TGACAGGATT CCTGACAAGG AGAACACACC TCTCATTGAA 
CCTCACGTTC CTCTTCGTCC TGCTAACACC ATTACCAAGG TCCCTTCAGA GAAGATCCTC 
AGAGCTGGAA AAATTTTACG AAATGCCATT CTCTCTCGAG CACCTCACAT GATAAGAGAT 
AGAAAATACC ACCTAAAGAC ATACAGACAA TGCTGTGTGG GAACTGAACT GGTGGACTGG 
ATGATGCAGC AGACACCATG TGTTCACTCC CGGACTCAAG CTGTTGGCAT GTGGCAAGTC 
CTGTTAGAAG ATGGTGTTCT CAACCACGTG GACCAGGAGC ACCATTTCCA AGACAAATAT 
TTATTCTATC GATTTCTGGA TGATGAGCAC GAGGATGCCC CTTTGCCTAC TGAGGAGGAG 
AAGAAGGAGT GTGATGAGGA GCTCCAGGAC ACCATGCTGC TGCTGTCACA GATGGGCCCC 
GACGCCCACA TGAGGATGAT CCTTCGCAAA CCACCTGGCC AGAGGACTGT GGATGACCTA 
GAGATTATCT ATGAGGAGCT TCTTCATATT AAAGCCTTAT CCCATCTTTC TACCACAGTG 
AAACGAGAGT TAGCAGGTGT TCTCATTTTT GAGTCTCACG CCAAAGGAGG GACTGTGTTG 
TTTAACCAGG GGGAAGAAGG TACCTCCTGG TACATTATTC TAAAAGGATC AGTGAATGTA 
GTCATTTACG GCAAGGGTGT GGTCTGCACC CTGCATGAAG GAGATGACTT CGGCAAGTTA 
GCACTAGTGA ATGATGCCCC ACGAGCTGCC TCTATCGTCT TACGAGAAGA TAACTGCCAT 
TTCTTAAGAG TAGACAAGGA GGATTTCAAC CGGATCCTAA GGGACGTGGA GGCGAATACA 
GTCAGACTTA AAGAACATGA CCAAGATGTC TTGGTGCTGG AGAAGGTCCC AGCAGGGAAC 
AGAGCTTCTA ATCAAGGAAA CTCACAGCCT CAGCAAAAGT ATACTGTGAT GTCAGGAACA 
CCTGAAAAAA TTTTAGAGCA TTTTCTAGAA ACAATACGCC TTGAGGCAAC TTTAAATGAA 
GCAACAGATT CTGTTTTAAA TGACTTTATT ATGATGCACT GTGTTTTTAT GCCAAATACC 
CAGCTTTGCC CGGCACTGGT GGCCCACTAC CACGCACAGC CTTCACAAGG TACAGAACAG 
GAGAAAATGG ATTATGCCCT CAACAATAAG AGGCGAGTCA TCCGCCTGGT TCTACAGTGG 
GCTGCCATGT ATGGAGACCT CCTGCAAGAG GATGACGTGT CTATGGCCTT CCTGGAGGAG 
TTTTATGTAT CTGTATCAGA TGATGCCCGG ATGATTGCTG CCCTCAAGGA GCAACTGCCA 
GAGTTGGAGA AGATTGTCAA GCAAATCTCA GAAGATGCAA AGGCACCACA AAAGAAGCAC 
AAGGTTCTTT TGCAACAGTT CAATACGGGC GATGAGAGAG CCCAGAAGCG CCAGCCTATC 
CGCGGCTCTG ATGAAGTTCT GTTTAAGGTC TATTGCATGG ACCACACCTA CACAACCATT 
CGGGTGCCAG TGGCCACTTC GGTGAAGGAA GTCATCAGTG CAGTTGCCGA CAAGCTGGGC 
TCCGGGGAGG GCCTGATCAT AGTCAAGATG AGTTCCGGAG GAGAAAAGGT GGTGCTCAAA 
CCTAATGATG TTTCAGTATT TACGACGCTC ACCATTAATG GACGCCTGTT TGCTTGCCCG 
CGAGAGCAAT TCGATTCACT GACTCCCTTA CCAGAACAGG AAGGCCCAAC TGTTGGAACA 
GTGGGAACTT TTGAACTGAT GAGCTCCAAA GATTTAGCAT ACCAGATGAC AATTTATGAT 
TGGGAACTCT TCAACTGCGT GCATGAGCTG GAGCTAATCT ATCACACATT TGGAAGGCAT 
AATTTTAAAA AGACCACAGC AAACTTGGAT TTGTTCCTGA GGAGATTTAA TGAAATTCAG 
TTTTGGGTCG TCACTGAGAT CTGCCTTTGT TCTCAGCTCA GCAAGCGTGT TCAGCTATTA 
AAAAAATTTA TTAAGATAGC AGCCCACTGT AAGGAGTATA AAAATCTGAA TTCCTTTTTT 
GCCATCGTCA TGGGACTAAG TAACGTTGCT GTGAGCCGCT TGGCACTAAC GTGGGAGAAA 
CTGCCAAGCA AGTTCAAGAA GTTCTATGCG GAGTTTGAAA GTTTAATGGA CCCTTCAAGG 
AACCACAGGG CCTACAGGCT GACAGTAGCT AAGCTGGAAC CTCCTCTCAT CCCCTTCATG 
CCTTTGCTCA TTAAAGATAT GACATTTACT CATGAGGGGA ACAAGACGTT CATTGACAAT 
CTAGTAAACT TTGAAAAAAT GCGCATGATT GCAAATACGG CCAGAACAGT GAGATACTAC 
AGGAGCCAAC CCTTCAATCC TGATGCAGCT CAAGCTAATA AGAACCATCA GGATGTCCGG 
AGTTATGTAC GGCAATTAAA TGTGATTGAC AACCAGAGAA CTTTATCACA GATGTCACAC 
AGATTAGAGC CTCGTCGACC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093867.1
CDS	141..2744
Translation	MLYKKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	NM_001100397.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100397.2

ORF Insert Sequence:

ATGCTCTACA AGAAATATCG ACAGTATATG GCAGGACTTC TGGCTCCTCC TTATGGTGTT 
ATGGAAACGG GCTCTAACAA TGACAGGATT CCTGACAAGG AGAACACACC TCTCATTGAA 
CCTCACGTTC CTCTTCGTCC TGCTAACACC ATTACCAAGG TCCCTTCAGA GAAGATCCTC 
AGAGCTGGAA AAATTTTACG AAATGCCATT CTCTCTCGAG CACCTCACAT GATAAGAGAT 
AGAAAATACC ACCTAAAGAC ATACAGACAA TGCTGTGTGG GAACTGAACT GGTGGACTGG 
ATGATGCAGC AGACACCATG TGTTCACTCC CGGACTCAAG CTGTTGGCAT GTGGCAAGTC 
CTGTTAGAAG ATGGTGTTCT CAACCACGTG GACCAGGAGC ACCATTTCCA AGACAAATAT 
TTATTCTATC GATTTCTGGA TGATGAGCAC GAGGATGCCC CTTTGCCTAC TGAGGAGGAG 
AAGAAGGAGT GTGATGAGGA GCTCCAGGAC ACCATGCTGC TGCTGTCACA GATGGGCCCC 
GACGCCCACA TGAGGATGAT CCTTCGCAAA CCACCTGGCC AGAGGACTGT GGATGACCTA 
GAGATTATCT ATGAGGAGCT TCTTCATATT AAAGCCTTAT CCCATCTTTC TACCACAGTG 
AAACGAGAGT TAGCAGGTGT TCTCATTTTT GAGTCTCACG CCAAAGGAGG GACTGTGTTG 
TTTAACCAGG GGGAAGAAGG TACCTCCTGG TACATTATTC TAAAAGGATC AGTGAATGTA 
GTCATTTACG GCAAGGGTGT GGTCTGCACC CTGCATGAAG GAGATGACTT CGGCAAGTTA 
GCACTAGTGA ATGATGCCCC ACGAGCTGCC TCTATCGTCT TACGAGAAGA TAACTGCCAT 
TTCTTAAGAG TAGACAAGGA GGATTTCAAC CGGATCCTAA GGGACGTGGA GGCGAATACA 
GTCAGACTTA AAGAACATGA CCAAGATGTC TTGGTGCTGG AGAAGGTCCC AGCAGGGAAC 
AGAGCTTCTA ATCAAGGAAA CTCACAGCCT CAGCAAAAGT ATACTGTGAT GTCAGGAACA 
CCTGAAAAAA TTTTAGAGCA TTTTCTAGAA ACAATACGCC TTGAGGCAAC TTTAAATGAA 
GCAACAGATT CTGTTTTAAA TGACTTTATT ATGATGCACT GTGTTTTTAT GCCAAATACC 
CAGCTTTGCC CGGCACTGGT GGCCCACTAC CACGCACAGC CTTCACAAGG TACAGAACAG 
GAGAAAATGG ATTATGCCCT CAACAATAAG AGGCGAGTCA TCCGCCTGGT TCTACAGTGG 
GCTGCCATGT ATGGAGACCT CCTGCAAGAG GATGACGTGT CTATGGCCTT CCTGGAGGAG 
TTTTATGTAT CTGTATCAGA TGATGCCCGG ATGATTGCTG CCCTCAAGGA GCAACTGCCA 
GAGTTGGAGA AGATTGTCAA GCAAATCTCA GAAGATGCAA AGGCACCACA AAAGAAGCAC 
AAGGTTCTTT TGCAACAGTT CAATACGGGC GATGAGAGAG CCCAGAAGCG CCAGCCTATC 
CGCGGCTCTG ATGAAGTTCT GTTTAAGGTC TATTGCATGG ACCACACCTA CACAACCATT 
CGGGTGCCAG TGGCCACTTC GGTGAAGGAA GTCATCAGTG CAGTTGCCGA CAAGCTGGGC 
TCCGGGGAGG GCCTGATCAT AGTCAAGATG AGTTCCGGAG GAGAAAAGGT GGTGCTCAAA 
CCTAATGATG TTTCAGTATT TACGACGCTC ACCATTAATG GACGCCTGTT TGCTTGCCCG 
CGAGAGCAAT TCGATTCACT GACTCCCTTA CCAGAACAGG AAGGCCCAAC TGTTGGAACA 
GTGGGAACTT TTGAACTGAT GAGCTCCAAA GATTTAGCAT ACCAGATGAC AATTTATGAT 
TGGGAACTCT TCAACTGCGT GCATGAGCTG GAGCTAATCT ATCACACATT TGGAAGGCAT 
AATTTTAAAA AGACCACAGC AAACTTGGAT TTGTTCCTGA GGAGATTTAA TGAAATTCAG 
TTTTGGGTCG TCACTGAGAT CTGCCTTTGT TCTCAGCTCA GCAAGCGTGT TCAGCTATTA 
AAAAAATTTA TTAAGATAGC AGCCCACTGT AAGGAGTATA AAAATCTGAA TTCCTTTTTT 
GCCATCGTCA TGGGACTAAG TAACGTTGCT GTGAGCCGCT TGGCACTAAC GTGGGAGAAA 
CTGCCAAGCA AGTTCAAGAA GTTCTATGCG GAGTTTGAAA GTTTAATGGA CCCTTCAAGG 
AACCACAGGG CCTACAGGCT GACAGTAGCT AAGCTGGAAC CTCCTCTCAT CCCCTTCATG 
CCTTTGCTCA TTAAAGATAT GACATTTACT CATGAGGGGA ACAAGACGTT CATTGACAAT 
CTAGTAAACT TTGAAAAAAT GCGCATGATT GCAAATACGG CCAGAACAGT GAGATACTAC 
AGGAGCCAAC CCTTCAATCC TGATGCAGCT CAAGCTAATA AGAACCATCA GGATGTCCGG 
AGTTATGTAC GGCAATTAAA TGTGATTGAC AACCAGAGAA CTTTATCACA GATGTCACAC 
AGATTAGAGC CTCGTCGACC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001282900.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269829.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 4, mRNA.

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CloneID	OHu20982
Clone ID Related Accession (Same CDS sequence)	NM_001282900.2 , NM_001282900.1 , XM_006712205.3
Accession Version	NM_001282900.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2523bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform d
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC009484.3, AC104086.6 and AC019046.4. On Nov 5, 2019 this sequence version replaced NM_001282900.1. Transcript Variant: This variant (4) differs in its 5' UTR, lacks several exons in the 5' coding region, initiates translation at a downstream in-frame start codon, and lacks an additional in-frame exon in the 5' coding region, compared to variant 1. The encoded isoform (d) is shorter at the N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK296340.1, SRR1660805.207914.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCAGGAC TTCTGGCTCC TCCTTATGGT GTTATGGAAA CGGGCTCTAA CAATGACAGG 
ATTCCTGACA AGGAGAACGT CCCTTCAGAG AAGATCCTCA GAGCTGGAAA AATTTTACGA 
AATGCCATTC TCTCTCGAGC ACCTCACATG ATAAGAGATA GAAAATACCA CCTAAAGACA 
TACAGACAAT GCTGTGTGGG AACTGAACTG GTGGACTGGA TGATGCAGCA GACACCATGT 
GTTCACTCCC GGACTCAAGC TGTTGGCATG TGGCAAGTCC TGTTAGAAGA TGGTGTTCTC 
AACCACGTGG ACCAGGAGCA CCATTTCCAA GACAAATATT TATTCTATCG ATTTCTGGAT 
GATGAGCACG AGGATGCCCC TTTGCCTACT GAGGAGGAGA AGAAGGAGTG TGATGAGGAG 
CTCCAGGACA CCATGCTGCT GCTGTCACAG ATGGGCCCCG ACGCCCACAT GAGGATGATC 
CTTCGCAAAC CACCTGGCCA GAGGACTGTG GATGACCTAG AGATTATCTA TGAGGAGCTT 
CTTCATATTA AAGCCTTATC CCATCTTTCT ACCACAGTGA AACGAGAGTT AGCAGGTGTT 
CTCATTTTTG AGTCTCACGC CAAAGGAGGG ACTGTGTTGT TTAACCAGGG GGAAGAAGGT 
ACCTCCTGGT ACATTATTCT AAAAGGATCA GTGAATGTAG TCATTTACGG CAAGGGTGTG 
GTCTGCACCC TGCATGAAGG AGATGACTTC GGCAAGTTAG CACTAGTGAA TGATGCCCCA 
CGAGCTGCCT CTATCGTCTT ACGAGAAGAT AACTGCCATT TCTTAAGAGT AGACAAGGAG 
GATTTCAACC GGATCCTAAG GGACGTGGAG GCGAATACAG TCAGACTTAA AGAACATGAC 
CAAGATGTCT TGGTGCTGGA GAAGGTCCCA GCAGGGAACA GAGCTTCTAA TCAAGGAAAC 
TCACAGCCTC AGCAAAAGTA TACTGTGATG TCAGGAACAC CTGAAAAAAT TTTAGAGCAT 
TTTCTAGAAA CAATACGCCT TGAGGCAACT TTAAATGAAG CAACAGATTC TGTTTTAAAT 
GACTTTATTA TGATGCACTG TGTTTTTATG CCAAATACCC AGCTTTGCCC GGCACTGGTG 
GCCCACTACC ACGCACAGCC TTCACAAGGT ACAGAACAGG AGAAAATGGA TTATGCCCTC 
AACAATAAGA GGCGAGTCAT CCGCCTGGTT CTACAGTGGG CTGCCATGTA TGGAGACCTC 
CTGCAAGAGG ATGACGTGTC TATGGCCTTC CTGGAGGAGT TTTATGTATC TGTATCAGAT 
GATGCCCGGA TGATTGCTGC CCTCAAGGAG CAACTGCCAG AGTTGGAGAA GATTGTCAAG 
CAAATCTCAG AAGATGCAAA GGCACCACAA AAGAAGCACA AGGTTCTTTT GCAACAGTTC 
AATACGGGCG ATGAGAGAGC CCAGAAGCGC CAGCCTATCC GCGGCTCTGA TGAAGTTCTG 
TTTAAGGTCT ATTGCATGGA CCACACCTAC ACAACCATTC GGGTGCCAGT GGCCACTTCG 
GTGAAGGAAG TCATCAGTGC AGTTGCCGAC AAGCTGGGCT CCGGGGAGGG CCTGATCATA 
GTCAAGATGA GTTCCGGAGG AGAAAAGGTG GTGCTCAAAC CTAATGATGT TTCAGTATTT 
ACGACGCTCA CCATTAATGG ACGCCTGTTT GCTTGCCCGC GAGAGCAATT CGATTCACTG 
ACTCCCTTAC CAGAACAGGA AGGCCCAACT GTTGGAACAG TGGGAACTTT TGAACTGATG 
AGCTCCAAAG ATTTAGCATA CCAGATGACA ATTTATGATT GGGAACTCTT CAACTGCGTG 
CATGAGCTGG AGCTAATCTA TCACACATTT GGAAGGCATA ATTTTAAAAA GACCACAGCA 
AACTTGGATT TGTTCCTGAG GAGATTTAAT GAAATTCAGT TTTGGGTCGT CACTGAGATC 
TGCCTTTGTT CTCAGCTCAG CAAGCGTGTT CAGCTATTAA AAAAATTTAT TAAGATAGCA 
GCCCACTGTA AGGAGTATAA AAATCTGAAT TCCTTTTTTG CCATCGTCAT GGGACTAAGT 
AACGTTGCTG TGAGCCGCTT GGCACTAACG TGGGAGAAAC TGCCAAGCAA GTTCAAGAAG 
TTCTATGCGG AGTTTGAAAG TTTAATGGAC CCTTCAAGGA ACCACAGGGC CTACAGGCTG 
ACAGTAGCTA AGCTGGAACC TCCTCTCATC CCCTTCATGC CTTTGCTCAT TAAAGATATG 
ACATTTACTC ATGAGGGGAA CAAGACGTTC ATTGACAATC TAGTAAACTT TGAAAAAATG 
CGCATGATTG CAAATACGGC CAGAACAGTG AGATACTACA GGAGCCAACC CTTCAATCCT 
GATGCAGCTC AAGCTAATAA GAACCATCAG GATGTCCGGA GTTATGTACG GCAATTAAAT 
GTGATTGACA ACCAGAGAAC TTTATCACAG ATGTCACACA GATTAGAGCC TCGTCGACCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269829.1
CDS	174..2696
Translation	MAGLLAPPYGVMETGSNNDRIPDKENVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	NM_001282900.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282900.2

ORF Insert Sequence:

ATGGCAGGAC TTCTGGCTCC TCCTTATGGT GTTATGGAAA CGGGCTCTAA CAATGACAGG 
ATTCCTGACA AGGAGAACGT CCCTTCAGAG AAGATCCTCA GAGCTGGAAA AATTTTACGA 
AATGCCATTC TCTCTCGAGC ACCTCACATG ATAAGAGATA GAAAATACCA CCTAAAGACA 
TACAGACAAT GCTGTGTGGG AACTGAACTG GTGGACTGGA TGATGCAGCA GACACCATGT 
GTTCACTCCC GGACTCAAGC TGTTGGCATG TGGCAAGTCC TGTTAGAAGA TGGTGTTCTC 
AACCACGTGG ACCAGGAGCA CCATTTCCAA GACAAATATT TATTCTATCG ATTTCTGGAT 
GATGAGCACG AGGATGCCCC TTTGCCTACT GAGGAGGAGA AGAAGGAGTG TGATGAGGAG 
CTCCAGGACA CCATGCTGCT GCTGTCACAG ATGGGCCCCG ACGCCCACAT GAGGATGATC 
CTTCGCAAAC CACCTGGCCA GAGGACTGTG GATGACCTAG AGATTATCTA TGAGGAGCTT 
CTTCATATTA AAGCCTTATC CCATCTTTCT ACCACAGTGA AACGAGAGTT AGCAGGTGTT 
CTCATTTTTG AGTCTCACGC CAAAGGAGGG ACTGTGTTGT TTAACCAGGG GGAAGAAGGT 
ACCTCCTGGT ACATTATTCT AAAAGGATCA GTGAATGTAG TCATTTACGG CAAGGGTGTG 
GTCTGCACCC TGCATGAAGG AGATGACTTC GGCAAGTTAG CACTAGTGAA TGATGCCCCA 
CGAGCTGCCT CTATCGTCTT ACGAGAAGAT AACTGCCATT TCTTAAGAGT AGACAAGGAG 
GATTTCAACC GGATCCTAAG GGACGTGGAG GCGAATACAG TCAGACTTAA AGAACATGAC 
CAAGATGTCT TGGTGCTGGA GAAGGTCCCA GCAGGGAACA GAGCTTCTAA TCAAGGAAAC 
TCACAGCCTC AGCAAAAGTA TACTGTGATG TCAGGAACAC CTGAAAAAAT TTTAGAGCAT 
TTTCTAGAAA CAATACGCCT TGAGGCAACT TTAAATGAAG CAACAGATTC TGTTTTAAAT 
GACTTTATTA TGATGCACTG TGTTTTTATG CCAAATACCC AGCTTTGCCC GGCACTGGTG 
GCCCACTACC ACGCACAGCC TTCACAAGGT ACAGAACAGG AGAAAATGGA TTATGCCCTC 
AACAATAAGA GGCGAGTCAT CCGCCTGGTT CTACAGTGGG CTGCCATGTA TGGAGACCTC 
CTGCAAGAGG ATGACGTGTC TATGGCCTTC CTGGAGGAGT TTTATGTATC TGTATCAGAT 
GATGCCCGGA TGATTGCTGC CCTCAAGGAG CAACTGCCAG AGTTGGAGAA GATTGTCAAG 
CAAATCTCAG AAGATGCAAA GGCACCACAA AAGAAGCACA AGGTTCTTTT GCAACAGTTC 
AATACGGGCG ATGAGAGAGC CCAGAAGCGC CAGCCTATCC GCGGCTCTGA TGAAGTTCTG 
TTTAAGGTCT ATTGCATGGA CCACACCTAC ACAACCATTC GGGTGCCAGT GGCCACTTCG 
GTGAAGGAAG TCATCAGTGC AGTTGCCGAC AAGCTGGGCT CCGGGGAGGG CCTGATCATA 
GTCAAGATGA GTTCCGGAGG AGAAAAGGTG GTGCTCAAAC CTAATGATGT TTCAGTATTT 
ACGACGCTCA CCATTAATGG ACGCCTGTTT GCTTGCCCGC GAGAGCAATT CGATTCACTG 
ACTCCCTTAC CAGAACAGGA AGGCCCAACT GTTGGAACAG TGGGAACTTT TGAACTGATG 
AGCTCCAAAG ATTTAGCATA CCAGATGACA ATTTATGATT GGGAACTCTT CAACTGCGTG 
CATGAGCTGG AGCTAATCTA TCACACATTT GGAAGGCATA ATTTTAAAAA GACCACAGCA 
AACTTGGATT TGTTCCTGAG GAGATTTAAT GAAATTCAGT TTTGGGTCGT CACTGAGATC 
TGCCTTTGTT CTCAGCTCAG CAAGCGTGTT CAGCTATTAA AAAAATTTAT TAAGATAGCA 
GCCCACTGTA AGGAGTATAA AAATCTGAAT TCCTTTTTTG CCATCGTCAT GGGACTAAGT 
AACGTTGCTG TGAGCCGCTT GGCACTAACG TGGGAGAAAC TGCCAAGCAA GTTCAAGAAG 
TTCTATGCGG AGTTTGAAAG TTTAATGGAC CCTTCAAGGA ACCACAGGGC CTACAGGCTG 
ACAGTAGCTA AGCTGGAACC TCCTCTCATC CCCTTCATGC CTTTGCTCAT TAAAGATATG 
ACATTTACTC ATGAGGGGAA CAAGACGTTC ATTGACAATC TAGTAAACTT TGAAAAAATG 
CGCATGATTG CAAATACGGC CAGAACAGTG AGATACTACA GGAGCCAACC CTTCAATCCT 
GATGCAGCTC AAGCTAATAA GAACCATCAG GATGTCCGGA GTTATGTACG GCAATTAAAT 
GTGATTGACA ACCAGAGAAC TTTATCACAG ATGTCACACA GATTAGAGCC TCGTCGACCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001282901.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269830.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu21563
Clone ID Related Accession (Same CDS sequence)	NM_001282901.1 , NM_001282901.2
Accession Version	NM_001282901.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2376bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-07
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform e
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC009484.3, AC104086.6 and AC019046.4. On Nov 8, 2019 this sequence version replaced NM_001282901.1. Transcript Variant: This variant (5) differs in its 5' UTR, lacks several exons in the 5' coding region, and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (e) is shorter at the N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK294433.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length.

ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG 
GTGGTGCTCA AACCTAATGA TGTTTCAGTA TTTACGACGC TCACCATTAA TGGACGCCTG 
TTTGCTTGCC CGCGAGAGCA ATTCGATTCA CTGACTCCCT TACCAGAACA GGAAGGCCCA 
ACTGTTGGAA CAGTGGGAAC TTTTGAACTG ATGAGCTCCA AAGATTTAGC ATACCAGATG 
ACAATTTATG ATTGGGAACT CTTCAACTGC GTGCATGAGC TGGAGCTAAT CTATCACACA 
TTTGGAAGGC ATAATTTTAA AAAGACCACA GCAAACTTGG ATTTGTTCCT GAGGAGATTT 
AATGAAATTC AGTTTTGGGT CGTCACTGAG ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT 
GTTCAGCTAT TAAAAAAATT TATTAAGATA GCAGCCCACT GTAAGGAGTA TAAAAATCTG 
AATTCCTTTT TTGCCATCGT CATGGGACTA AGTAACGTTG CTGTGAGCCG CTTGGCACTA 
ACGTGGGAGA AACTGCCAAG CAAGTTCAAG AAGTTCTATG CGGAGTTTGA AAGTTTAATG 
GACCCTTCAA GGAACCACAG GGCCTACAGG CTGACAGTAG CTAAGCTGGA ACCTCCTCTC 
ATCCCCTTCA TGCCTTTGCT CATTAAAGAT ATGACATTTA CTCATGAGGG GAACAAGACG 
TTCATTGACA ATCTAGTAAA CTTTGAAAAA ATGCGCATGA TTGCAAATAC GGCCAGAACA 
GTGAGATACT ACAGGAGCCA ACCCTTCAAT CCTGATGCAG CTCAAGCTAA TAAGAACCAT 
CAGGATGTCC GGAGTTATGT ACGGCAATTA AATGTGATTG ACAACCAGAG AACTTTATCA 
CAGATGTCAC ACAGATTAGA GCCTCGTCGA CCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269830.1
CDS	265..2640
Translation	MIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	NM_001282901.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282901.2

ORF Insert Sequence:

ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG 
GTGGTGCTCA AACCTAATGA TGTTTCAGTA TTTACGACGC TCACCATTAA TGGACGCCTG 
TTTGCTTGCC CGCGAGAGCA ATTCGATTCA CTGACTCCCT TACCAGAACA GGAAGGCCCA 
ACTGTTGGAA CAGTGGGAAC TTTTGAACTG ATGAGCTCCA AAGATTTAGC ATACCAGATG 
ACAATTTATG ATTGGGAACT CTTCAACTGC GTGCATGAGC TGGAGCTAAT CTATCACACA 
TTTGGAAGGC ATAATTTTAA AAAGACCACA GCAAACTTGG ATTTGTTCCT GAGGAGATTT 
AATGAAATTC AGTTTTGGGT CGTCACTGAG ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT 
GTTCAGCTAT TAAAAAAATT TATTAAGATA GCAGCCCACT GTAAGGAGTA TAAAAATCTG 
AATTCCTTTT TTGCCATCGT CATGGGACTA AGTAACGTTG CTGTGAGCCG CTTGGCACTA 
ACGTGGGAGA AACTGCCAAG CAAGTTCAAG AAGTTCTATG CGGAGTTTGA AAGTTTAATG 
GACCCTTCAA GGAACCACAG GGCCTACAGG CTGACAGTAG CTAAGCTGGA ACCTCCTCTC 
ATCCCCTTCA TGCCTTTGCT CATTAAAGAT ATGACATTTA CTCATGAGGG GAACAAGACG 
TTCATTGACA ATCTAGTAAA CTTTGAAAAA ATGCGCATGA TTGCAAATAC GGCCAGAACA 
GTGAGATACT ACAGGAGCCA ACCCTTCAAT CCTGATGCAG CTCAAGCTAA TAAGAACCAT 
CAGGATGTCC GGAGTTATGT ACGGCAATTA AATGTGATTG ACAACCAGAG AACTTTATCA 
CAGATGTCAC ACAGATTAGA GCCTCGTCGA CCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001282899.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269828.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu21628
Clone ID Related Accession (Same CDS sequence)	NM_001282899.1 , NM_001282899.2
Accession Version	NM_001282899.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2577bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC009484.3, AC104086.6 and AC019046.4. On Nov 5, 2019 this sequence version replaced NM_001282899.1. Transcript Variant: This variant (3) differs in its 5' UTR, lacks several exons in the 5' coding region, and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (c) is shorter at the N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK316072.1, AK316014.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCAGGAC TTCTGGCTCC TCCTTATGGT GTTATGGAAA CGGGCTCTAA CAATGACAGG 
ATTCCTGACA AGGAGAACAC ACCTCTCATT GAACCTCACG TTCCTCTTCG TCCTGCTAAC 
ACCATTACCA AGGTCCCTTC AGAGAAGATC CTCAGAGCTG GAAAAATTTT ACGAAATGCC 
ATTCTCTCTC GAGCACCTCA CATGATAAGA GATAGAAAAT ACCACCTAAA GACATACAGA 
CAATGCTGTG TGGGAACTGA ACTGGTGGAC TGGATGATGC AGCAGACACC ATGTGTTCAC 
TCCCGGACTC AAGCTGTTGG CATGTGGCAA GTCCTGTTAG AAGATGGTGT TCTCAACCAC 
GTGGACCAGG AGCACCATTT CCAAGACAAA TATTTATTCT ATCGATTTCT GGATGATGAG 
CACGAGGATG CCCCTTTGCC TACTGAGGAG GAGAAGAAGG AGTGTGATGA GGAGCTCCAG 
GACACCATGC TGCTGCTGTC ACAGATGGGC CCCGACGCCC ACATGAGGAT GATCCTTCGC 
AAACCACCTG GCCAGAGGAC TGTGGATGAC CTAGAGATTA TCTATGAGGA GCTTCTTCAT 
ATTAAAGCCT TATCCCATCT TTCTACCACA GTGAAACGAG AGTTAGCAGG TGTTCTCATT 
TTTGAGTCTC ACGCCAAAGG AGGGACTGTG TTGTTTAACC AGGGGGAAGA AGGTACCTCC 
TGGTACATTA TTCTAAAAGG ATCAGTGAAT GTAGTCATTT ACGGCAAGGG TGTGGTCTGC 
ACCCTGCATG AAGGAGATGA CTTCGGCAAG TTAGCACTAG TGAATGATGC CCCACGAGCT 
GCCTCTATCG TCTTACGAGA AGATAACTGC CATTTCTTAA GAGTAGACAA GGAGGATTTC 
AACCGGATCC TAAGGGACGT GGAGGCGAAT ACAGTCAGAC TTAAAGAACA TGACCAAGAT 
GTCTTGGTGC TGGAGAAGGT CCCAGCAGGG AACAGAGCTT CTAATCAAGG AAACTCACAG 
CCTCAGCAAA AGTATACTGT GATGTCAGGA ACACCTGAAA AAATTTTAGA GCATTTTCTA 
GAAACAATAC GCCTTGAGGC AACTTTAAAT GAAGCAACAG ATTCTGTTTT AAATGACTTT 
ATTATGATGC ACTGTGTTTT TATGCCAAAT ACCCAGCTTT GCCCGGCACT GGTGGCCCAC 
TACCACGCAC AGCCTTCACA AGGTACAGAA CAGGAGAAAA TGGATTATGC CCTCAACAAT 
AAGAGGCGAG TCATCCGCCT GGTTCTACAG TGGGCTGCCA TGTATGGAGA CCTCCTGCAA 
GAGGATGACG TGTCTATGGC CTTCCTGGAG GAGTTTTATG TATCTGTATC AGATGATGCC 
CGGATGATTG CTGCCCTCAA GGAGCAACTG CCAGAGTTGG AGAAGATTGT CAAGCAAATC 
TCAGAAGATG CAAAGGCACC ACAAAAGAAG CACAAGGTTC TTTTGCAACA GTTCAATACG 
GGCGATGAGA GAGCCCAGAA GCGCCAGCCT ATCCGCGGCT CTGATGAAGT TCTGTTTAAG 
GTCTATTGCA TGGACCACAC CTACACAACC ATTCGGGTGC CAGTGGCCAC TTCGGTGAAG 
GAAGTCATCA GTGCAGTTGC CGACAAGCTG GGCTCCGGGG AGGGCCTGAT CATAGTCAAG 
ATGAGTTCCG GAGGAGAAAA GGTGGTGCTC AAACCTAATG ATGTTTCAGT ATTTACGACG 
CTCACCATTA ATGGACGCCT GTTTGCTTGC CCGCGAGAGC AATTCGATTC ACTGACTCCC 
TTACCAGAAC AGGAAGGCCC AACTGTTGGA ACAGTGGGAA CTTTTGAACT GATGAGCTCC 
AAAGATTTAG CATACCAGAT GACAATTTAT GATTGGGAAC TCTTCAACTG CGTGCATGAG 
CTGGAGCTAA TCTATCACAC ATTTGGAAGG CATAATTTTA AAAAGACCAC AGCAAACTTG 
GATTTGTTCC TGAGGAGATT TAATGAAATT CAGTTTTGGG TCGTCACTGA GATCTGCCTT 
TGTTCTCAGC TCAGCAAGCG TGTTCAGCTA TTAAAAAAAT TTATTAAGAT AGCAGCCCAC 
TGTAAGGAGT ATAAAAATCT GAATTCCTTT TTTGCCATCG TCATGGGACT AAGTAACGTT 
GCTGTGAGCC GCTTGGCACT AACGTGGGAG AAACTGCCAA GCAAGTTCAA GAAGTTCTAT 
GCGGAGTTTG AAAGTTTAAT GGACCCTTCA AGGAACCACA GGGCCTACAG GCTGACAGTA 
GCTAAGCTGG AACCTCCTCT CATCCCCTTC ATGCCTTTGC TCATTAAAGA TATGACATTT 
ACTCATGAGG GGAACAAGAC GTTCATTGAC AATCTAGTAA ACTTTGAAAA AATGCGCATG 
ATTGCAAATA CGGCCAGAAC AGTGAGATAC TACAGGAGCC AACCCTTCAA TCCTGATGCA 
GCTCAAGCTA ATAAGAACCA TCAGGATGTC CGGAGTTATG TACGGCAATT AAATGTGATT 
GACAACCAGA GAACTTTATC ACAGATGTCA CACAGATTAG AGCCTCGTCG ACCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269828.1
CDS	174..2750
Translation	MAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	NM_001282899.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282899.2

ORF Insert Sequence:

ATGGCAGGAC TTCTGGCTCC TCCTTATGGT GTTATGGAAA CGGGCTCTAA CAATGACAGG 
ATTCCTGACA AGGAGAACAC ACCTCTCATT GAACCTCACG TTCCTCTTCG TCCTGCTAAC 
ACCATTACCA AGGTCCCTTC AGAGAAGATC CTCAGAGCTG GAAAAATTTT ACGAAATGCC 
ATTCTCTCTC GAGCACCTCA CATGATAAGA GATAGAAAAT ACCACCTAAA GACATACAGA 
CAATGCTGTG TGGGAACTGA ACTGGTGGAC TGGATGATGC AGCAGACACC ATGTGTTCAC 
TCCCGGACTC AAGCTGTTGG CATGTGGCAA GTCCTGTTAG AAGATGGTGT TCTCAACCAC 
GTGGACCAGG AGCACCATTT CCAAGACAAA TATTTATTCT ATCGATTTCT GGATGATGAG 
CACGAGGATG CCCCTTTGCC TACTGAGGAG GAGAAGAAGG AGTGTGATGA GGAGCTCCAG 
GACACCATGC TGCTGCTGTC ACAGATGGGC CCCGACGCCC ACATGAGGAT GATCCTTCGC 
AAACCACCTG GCCAGAGGAC TGTGGATGAC CTAGAGATTA TCTATGAGGA GCTTCTTCAT 
ATTAAAGCCT TATCCCATCT TTCTACCACA GTGAAACGAG AGTTAGCAGG TGTTCTCATT 
TTTGAGTCTC ACGCCAAAGG AGGGACTGTG TTGTTTAACC AGGGGGAAGA AGGTACCTCC 
TGGTACATTA TTCTAAAAGG ATCAGTGAAT GTAGTCATTT ACGGCAAGGG TGTGGTCTGC 
ACCCTGCATG AAGGAGATGA CTTCGGCAAG TTAGCACTAG TGAATGATGC CCCACGAGCT 
GCCTCTATCG TCTTACGAGA AGATAACTGC CATTTCTTAA GAGTAGACAA GGAGGATTTC 
AACCGGATCC TAAGGGACGT GGAGGCGAAT ACAGTCAGAC TTAAAGAACA TGACCAAGAT 
GTCTTGGTGC TGGAGAAGGT CCCAGCAGGG AACAGAGCTT CTAATCAAGG AAACTCACAG 
CCTCAGCAAA AGTATACTGT GATGTCAGGA ACACCTGAAA AAATTTTAGA GCATTTTCTA 
GAAACAATAC GCCTTGAGGC AACTTTAAAT GAAGCAACAG ATTCTGTTTT AAATGACTTT 
ATTATGATGC ACTGTGTTTT TATGCCAAAT ACCCAGCTTT GCCCGGCACT GGTGGCCCAC 
TACCACGCAC AGCCTTCACA AGGTACAGAA CAGGAGAAAA TGGATTATGC CCTCAACAAT 
AAGAGGCGAG TCATCCGCCT GGTTCTACAG TGGGCTGCCA TGTATGGAGA CCTCCTGCAA 
GAGGATGACG TGTCTATGGC CTTCCTGGAG GAGTTTTATG TATCTGTATC AGATGATGCC 
CGGATGATTG CTGCCCTCAA GGAGCAACTG CCAGAGTTGG AGAAGATTGT CAAGCAAATC 
TCAGAAGATG CAAAGGCACC ACAAAAGAAG CACAAGGTTC TTTTGCAACA GTTCAATACG 
GGCGATGAGA GAGCCCAGAA GCGCCAGCCT ATCCGCGGCT CTGATGAAGT TCTGTTTAAG 
GTCTATTGCA TGGACCACAC CTACACAACC ATTCGGGTGC CAGTGGCCAC TTCGGTGAAG 
GAAGTCATCA GTGCAGTTGC CGACAAGCTG GGCTCCGGGG AGGGCCTGAT CATAGTCAAG 
ATGAGTTCCG GAGGAGAAAA GGTGGTGCTC AAACCTAATG ATGTTTCAGT ATTTACGACG 
CTCACCATTA ATGGACGCCT GTTTGCTTGC CCGCGAGAGC AATTCGATTC ACTGACTCCC 
TTACCAGAAC AGGAAGGCCC AACTGTTGGA ACAGTGGGAA CTTTTGAACT GATGAGCTCC 
AAAGATTTAG CATACCAGAT GACAATTTAT GATTGGGAAC TCTTCAACTG CGTGCATGAG 
CTGGAGCTAA TCTATCACAC ATTTGGAAGG CATAATTTTA AAAAGACCAC AGCAAACTTG 
GATTTGTTCC TGAGGAGATT TAATGAAATT CAGTTTTGGG TCGTCACTGA GATCTGCCTT 
TGTTCTCAGC TCAGCAAGCG TGTTCAGCTA TTAAAAAAAT TTATTAAGAT AGCAGCCCAC 
TGTAAGGAGT ATAAAAATCT GAATTCCTTT TTTGCCATCG TCATGGGACT AAGTAACGTT 
GCTGTGAGCC GCTTGGCACT AACGTGGGAG AAACTGCCAA GCAAGTTCAA GAAGTTCTAT 
GCGGAGTTTG AAAGTTTAAT GGACCCTTCA AGGAACCACA GGGCCTACAG GCTGACAGTA 
GCTAAGCTGG AACCTCCTCT CATCCCCTTC ATGCCTTTGC TCATTAAAGA TATGACATTT 
ACTCATGAGG GGAACAAGAC GTTCATTGAC AATCTAGTAA ACTTTGAAAA AATGCGCATG 
ATTGCAAATA CGGCCAGAAC AGTGAGATAC TACAGGAGCC AACCCTTCAA TCCTGATGCA 
GCTCAAGCTA ATAAGAACCA TCAGGATGTC CGGAGTTATG TACGGCAATT AAATGTGATT 
GACAACCAGA GAACTTTATC ACAGATGTCA CACAGATTAG AGCCTCGTCG ACCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001375866.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001362795.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 8, mRNA.

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CloneID	OHu35775
Clone ID Related Accession (Same CDS sequence)	XM_005246246.3 , XM_005246246.2 , NM_001375866.1
Accession Version	NM_001375866.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2982bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform h
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018712.5, AC009484.3, AC104086.6 and AC019046.4. On Nov 5, 2019 this sequence version replaced XM_005246246.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: KJ534925.1, SRR1660809.217188.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACGTC 
CCTTCAGAGA AGATCCTCAG AGCTGGAAAA ATTTTACGAA ATGCCATTCT CTCTCGAGCA 
CCTCACATGA TAAGAGATAG AAAATACCAC CTAAAGACAT ACAGACAATG CTGTGTGGGA 
ACTGAACTGG TGGACTGGAT GATGCAGCAG ACACCATGTG TTCACTCCCG GACTCAAGCT 
GTTGGCATGT GGCAAGTCCT GTTAGAAGAT GGTGTTCTCA ACCACGTGGA CCAGGAGCAC 
CATTTCCAAG ACAAATATTT ATTCTATCGA TTTCTGGATG ATGAGCACGA GGATGCCCCT 
TTGCCTACTG AGGAGGAGAA GAAGGAGTGT GATGAGGAGC TCCAGGACAC CATGCTGCTG 
CTGTCACAGA TGGGCCCCGA CGCCCACATG AGGATGATCC TTCGCAAACC ACCTGGCCAG 
AGGACTGTGG ATGACCTAGA GATTATCTAT GAGGAGCTTC TTCATATTAA AGCCTTATCC 
CATCTTTCTA CCACAGTGAA ACGAGAGTTA GCAGGTGTTC TCATTTTTGA GTCTCACGCC 
AAAGGAGGGA CTGTGTTGTT TAACCAGGGG GAAGAAGGTA CCTCCTGGTA CATTATTCTA 
AAAGGATCAG TGAATGTAGT CATTTACGGC AAGGGTGTGG TCTGCACCCT GCATGAAGGA 
GATGACTTCG GCAAGTTAGC ACTAGTGAAT GATGCCCCAC GAGCTGCCTC TATCGTCTTA 
CGAGAAGATA ACTGCCATTT CTTAAGAGTA GACAAGGAGG ATTTCAACCG GATCCTAAGG 
GACGTGGAGG CGAATACAGT CAGACTTAAA GAACATGACC AAGATGTCTT GGTGCTGGAG 
AAGGTCCCAG CAGGGAACAG AGCTTCTAAT CAAGGAAACT CACAGCCTCA GCAAAAGTAT 
ACTGTGATGT CAGGAACACC TGAAAAAATT TTAGAGCATT TTCTAGAAAC AATACGCCTT 
GAGGCAACTT TAAATGAAGC AACAGATTCT GTTTTAAATG ACTTTATTAT GATGCACTGT 
GTTTTTATGC CAAATACCCA GCTTTGCCCG GCACTGGTGG CCCACTACCA CGCACAGCCT 
TCACAAGGTA CAGAACAGGA GAAAATGGAT TATGCCCTCA ACAATAAGAG GCGAGTCATC 
CGCCTGGTTC TACAGTGGGC TGCCATGTAT GGAGACCTCC TGCAAGAGGA TGACGTGTCT 
ATGGCCTTCC TGGAGGAGTT TTATGTATCT GTATCAGATG ATGCCCGGAT GATTGCTGCC 
CTCAAGGAGC AACTGCCAGA GTTGGAGAAG ATTGTCAAGC AAATCTCAGA AGATGCAAAG 
GCACCACAAA AGAAGCACAA GGTTCTTTTG CAACAGTTCA ATACGGGCGA TGAGAGAGCC 
CAGAAGCGCC AGCCTATCCG CGGCTCTGAT GAAGTTCTGT TTAAGGTCTA TTGCATGGAC 
CACACCTACA CAACCATTCG GGTGCCAGTG GCCACTTCGG TGAAGGAAGT CATCAGTGCA 
GTTGCCGACA AGCTGGGCTC CGGGGAGGGC CTGATCATAG TCAAGATGAG TTCCGGAGGA 
GAAAAGGTGG TGCTCAAACC TAATGATGTT TCAGTATTTA CGACGCTCAC CATTAATGGA 
CGCCTGTTTG CTTGCCCGCG AGAGCAATTC GATTCACTGA CTCCCTTACC AGAACAGGAA 
GGCCCAACTG TTGGAACAGT GGGAACTTTT GAACTGATGA GCTCCAAAGA TTTAGCATAC 
CAGATGACAA TTTATGATTG GGAACTCTTC AACTGCGTGC ATGAGCTGGA GCTAATCTAT 
CACACATTTG GAAGGCATAA TTTTAAAAAG ACCACAGCAA ACTTGGATTT GTTCCTGAGG 
AGATTTAATG AAATTCAGTT TTGGGTCGTC ACTGAGATCT GCCTTTGTTC TCAGCTCAGC 
AAGCGTGTTC AGCTATTAAA AAAATTTATT AAGATAGCAG CCCACTGTAA GGAGTATAAA 
AATCTGAATT CCTTTTTTGC CATCGTCATG GGACTAAGTA ACGTTGCTGT GAGCCGCTTG 
GCACTAACGT GGGAGAAACT GCCAAGCAAG TTCAAGAAGT TCTATGCGGA GTTTGAAAGT 
TTAATGGACC CTTCAAGGAA CCACAGGGCC TACAGGCTGA CAGTAGCTAA GCTGGAACCT 
CCTCTCATCC CCTTCATGCC TTTGCTCATT AAAGATATGA CATTTACTCA TGAGGGGAAC 
AAGACGTTCA TTGACAATCT AGTAAACTTT GAAAAAATGC GCATGATTGC AAATACGGCC 
AGAACAGTGA GATACTACAG GAGCCAACCC TTCAATCCTG ATGCAGCTCA AGCTAATAAG 
AACCATCAGG ATGTCCGGAG TTATGTACGG CAATTAAATG TGATTGACAA CCAGAGAACT 
TTATCACAGA TGTCACACAG ATTAGAGCCT CGTCGACCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001362795.1
CDS	140..3121
Translation	MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	NM_001375866.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001375866.1

ORF Insert Sequence:

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACGTC 
CCTTCAGAGA AGATCCTCAG AGCTGGAAAA ATTTTACGAA ATGCCATTCT CTCTCGAGCA 
CCTCACATGA TAAGAGATAG AAAATACCAC CTAAAGACAT ACAGACAATG CTGTGTGGGA 
ACTGAACTGG TGGACTGGAT GATGCAGCAG ACACCATGTG TTCACTCCCG GACTCAAGCT 
GTTGGCATGT GGCAAGTCCT GTTAGAAGAT GGTGTTCTCA ACCACGTGGA CCAGGAGCAC 
CATTTCCAAG ACAAATATTT ATTCTATCGA TTTCTGGATG ATGAGCACGA GGATGCCCCT 
TTGCCTACTG AGGAGGAGAA GAAGGAGTGT GATGAGGAGC TCCAGGACAC CATGCTGCTG 
CTGTCACAGA TGGGCCCCGA CGCCCACATG AGGATGATCC TTCGCAAACC ACCTGGCCAG 
AGGACTGTGG ATGACCTAGA GATTATCTAT GAGGAGCTTC TTCATATTAA AGCCTTATCC 
CATCTTTCTA CCACAGTGAA ACGAGAGTTA GCAGGTGTTC TCATTTTTGA GTCTCACGCC 
AAAGGAGGGA CTGTGTTGTT TAACCAGGGG GAAGAAGGTA CCTCCTGGTA CATTATTCTA 
AAAGGATCAG TGAATGTAGT CATTTACGGC AAGGGTGTGG TCTGCACCCT GCATGAAGGA 
GATGACTTCG GCAAGTTAGC ACTAGTGAAT GATGCCCCAC GAGCTGCCTC TATCGTCTTA 
CGAGAAGATA ACTGCCATTT CTTAAGAGTA GACAAGGAGG ATTTCAACCG GATCCTAAGG 
GACGTGGAGG CGAATACAGT CAGACTTAAA GAACATGACC AAGATGTCTT GGTGCTGGAG 
AAGGTCCCAG CAGGGAACAG AGCTTCTAAT CAAGGAAACT CACAGCCTCA GCAAAAGTAT 
ACTGTGATGT CAGGAACACC TGAAAAAATT TTAGAGCATT TTCTAGAAAC AATACGCCTT 
GAGGCAACTT TAAATGAAGC AACAGATTCT GTTTTAAATG ACTTTATTAT GATGCACTGT 
GTTTTTATGC CAAATACCCA GCTTTGCCCG GCACTGGTGG CCCACTACCA CGCACAGCCT 
TCACAAGGTA CAGAACAGGA GAAAATGGAT TATGCCCTCA ACAATAAGAG GCGAGTCATC 
CGCCTGGTTC TACAGTGGGC TGCCATGTAT GGAGACCTCC TGCAAGAGGA TGACGTGTCT 
ATGGCCTTCC TGGAGGAGTT TTATGTATCT GTATCAGATG ATGCCCGGAT GATTGCTGCC 
CTCAAGGAGC AACTGCCAGA GTTGGAGAAG ATTGTCAAGC AAATCTCAGA AGATGCAAAG 
GCACCACAAA AGAAGCACAA GGTTCTTTTG CAACAGTTCA ATACGGGCGA TGAGAGAGCC 
CAGAAGCGCC AGCCTATCCG CGGCTCTGAT GAAGTTCTGT TTAAGGTCTA TTGCATGGAC 
CACACCTACA CAACCATTCG GGTGCCAGTG GCCACTTCGG TGAAGGAAGT CATCAGTGCA 
GTTGCCGACA AGCTGGGCTC CGGGGAGGGC CTGATCATAG TCAAGATGAG TTCCGGAGGA 
GAAAAGGTGG TGCTCAAACC TAATGATGTT TCAGTATTTA CGACGCTCAC CATTAATGGA 
CGCCTGTTTG CTTGCCCGCG AGAGCAATTC GATTCACTGA CTCCCTTACC AGAACAGGAA 
GGCCCAACTG TTGGAACAGT GGGAACTTTT GAACTGATGA GCTCCAAAGA TTTAGCATAC 
CAGATGACAA TTTATGATTG GGAACTCTTC AACTGCGTGC ATGAGCTGGA GCTAATCTAT 
CACACATTTG GAAGGCATAA TTTTAAAAAG ACCACAGCAA ACTTGGATTT GTTCCTGAGG 
AGATTTAATG AAATTCAGTT TTGGGTCGTC ACTGAGATCT GCCTTTGTTC TCAGCTCAGC 
AAGCGTGTTC AGCTATTAAA AAAATTTATT AAGATAGCAG CCCACTGTAA GGAGTATAAA 
AATCTGAATT CCTTTTTTGC CATCGTCATG GGACTAAGTA ACGTTGCTGT GAGCCGCTTG 
GCACTAACGT GGGAGAAACT GCCAAGCAAG TTCAAGAAGT TCTATGCGGA GTTTGAAAGT 
TTAATGGACC CTTCAAGGAA CCACAGGGCC TACAGGCTGA CAGTAGCTAA GCTGGAACCT 
CCTCTCATCC CCTTCATGCC TTTGCTCATT AAAGATATGA CATTTACTCA TGAGGGGAAC 
AAGACGTTCA TTGACAATCT AGTAAACTTT GAAAAAATGC GCATGATTGC AAATACGGCC 
AGAACAGTGA GATACTACAG GAGCCAACCC TTCAATCCTG ATGCAGCTCA AGCTAATAAG 
AACCATCAGG ATGTCCGGAG TTATGTACGG CAATTAAATG TGATTGACAA CCAGAGAACT 
TTATCACAGA TGTCACACAG ATTAGAGCCT CGTCGACCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( XM_017003196.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016858685.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu88944
Clone ID Related Accession (Same CDS sequence)	XM_017003196.1 , XM_017003196.2
Accession Version	XM_017003196.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2883bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG 
GTGGTGCTCA AACCTAATGA TGTTTCAGTA TTTACGACGC TCACCATTAA TGGACGCCTG 
TTTGCTTGCC CGCGAGAGCA ATTCGATTCA CTGACTCCCT TACCAGAACA GGAAGGCCCA 
ACTGTTGGAA CAGTGGGAAC TTTTGAACTG ATGAGCTCCA AAGATTTAGC ATACCAGATG 
ACAATTTATG ATTGGGAACT CTTCAACTGC GTGCATGAGC TGGAGCTAAT CTATCACACA 
TTTGGAAGGC ATAATTTTAA AAAGACCACA GCAAACTTGG ATTTGTTCCT GAGGAGATTT 
AATGAAATTC AGTTTTGGGT CGTCACTGAG ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT 
GTTCAGCTAT TAAAAAAATT TATTAAGATA GCAGCCCACT GTAAGGAGTA TAAAAATCTG 
AATTCCTTTT TTGCCATCGT CATGGGACTA AGTAACGTTG CTGTGAGCCG CTTGGCACTA 
ACGTGGGAGA AACTGCCAAG CAAGTTCAAG AAGTTCTATG CGGAGTTTGA AAGTTTAATG 
GACCCTTCAA GGAACCACAG GGCCTACAGG CTGACAGTAG CTAAGCTGGA ACCTCCTCTC 
ATCCCCTTCA TGCCTTTGCT CATTAAAGAT ATGACATTTA CTCATGAGGG GAACAAGACG 
TTCATTGACA ATCTAGTAAA CTTTGAAAAA ATGCCTGTTG CTGAAATGCA CAAATGTTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016858685.1
CDS	55..2937
Translation	MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMPVAEMHKCS

Target ORF information:

RefSeq Version	XM_017003196.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017003196.1

ORF Insert Sequence:

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG 
GTGGTGCTCA AACCTAATGA TGTTTCAGTA TTTACGACGC TCACCATTAA TGGACGCCTG 
TTTGCTTGCC CGCGAGAGCA ATTCGATTCA CTGACTCCCT TACCAGAACA GGAAGGCCCA 
ACTGTTGGAA CAGTGGGAAC TTTTGAACTG ATGAGCTCCA AAGATTTAGC ATACCAGATG 
ACAATTTATG ATTGGGAACT CTTCAACTGC GTGCATGAGC TGGAGCTAAT CTATCACACA 
TTTGGAAGGC ATAATTTTAA AAAGACCACA GCAAACTTGG ATTTGTTCCT GAGGAGATTT 
AATGAAATTC AGTTTTGGGT CGTCACTGAG ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT 
GTTCAGCTAT TAAAAAAATT TATTAAGATA GCAGCCCACT GTAAGGAGTA TAAAAATCTG 
AATTCCTTTT TTGCCATCGT CATGGGACTA AGTAACGTTG CTGTGAGCCG CTTGGCACTA 
ACGTGGGAGA AACTGCCAAG CAAGTTCAAG AAGTTCTATG CGGAGTTTGA AAGTTTAATG 
GACCCTTCAA GGAACCACAG GGCCTACAGG CTGACAGTAG CTAAGCTGGA ACCTCCTCTC 
ATCCCCTTCA TGCCTTTGCT CATTAAAGAT ATGACATTTA CTCATGAGGG GAACAAGACG 
TTCATTGACA ATCTAGTAAA CTTTGAAAAA ATGCCTGTTG CTGAAATGCA CAAATGTTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( XM_017003196.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016858685.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X2, mRNA.

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CloneID	OHu88944
Clone ID Related Accession (Same CDS sequence)	XM_017003196.1 , XM_017003196.2
Accession Version	XM_017003196.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2883bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017003196.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG 
GTGGTGCTCA AACCTAATGA TGTTTCAGTA TTTACGACGC TCACCATTAA TGGACGCCTG 
TTTGCTTGCC CGCGAGAGCA ATTCGATTCA CTGACTCCCT TACCAGAACA GGAAGGCCCA 
ACTGTTGGAA CAGTGGGAAC TTTTGAACTG ATGAGCTCCA AAGATTTAGC ATACCAGATG 
ACAATTTATG ATTGGGAACT CTTCAACTGC GTGCATGAGC TGGAGCTAAT CTATCACACA 
TTTGGAAGGC ATAATTTTAA AAAGACCACA GCAAACTTGG ATTTGTTCCT GAGGAGATTT 
AATGAAATTC AGTTTTGGGT CGTCACTGAG ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT 
GTTCAGCTAT TAAAAAAATT TATTAAGATA GCAGCCCACT GTAAGGAGTA TAAAAATCTG 
AATTCCTTTT TTGCCATCGT CATGGGACTA AGTAACGTTG CTGTGAGCCG CTTGGCACTA 
ACGTGGGAGA AACTGCCAAG CAAGTTCAAG AAGTTCTATG CGGAGTTTGA AAGTTTAATG 
GACCCTTCAA GGAACCACAG GGCCTACAGG CTGACAGTAG CTAAGCTGGA ACCTCCTCTC 
ATCCCCTTCA TGCCTTTGCT CATTAAAGAT ATGACATTTA CTCATGAGGG GAACAAGACG 
TTCATTGACA ATCTAGTAAA CTTTGAAAAA ATGCCTGTTG CTGAAATGCA CAAATGTTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016858685.1
CDS	59..2941
Translation	MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMPVAEMHKCS

Target ORF information:

RefSeq Version	XM_017003196.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017003196.2

ORF Insert Sequence:

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG 
GTGGTGCTCA AACCTAATGA TGTTTCAGTA TTTACGACGC TCACCATTAA TGGACGCCTG 
TTTGCTTGCC CGCGAGAGCA ATTCGATTCA CTGACTCCCT TACCAGAACA GGAAGGCCCA 
ACTGTTGGAA CAGTGGGAAC TTTTGAACTG ATGAGCTCCA AAGATTTAGC ATACCAGATG 
ACAATTTATG ATTGGGAACT CTTCAACTGC GTGCATGAGC TGGAGCTAAT CTATCACACA 
TTTGGAAGGC ATAATTTTAA AAAGACCACA GCAAACTTGG ATTTGTTCCT GAGGAGATTT 
AATGAAATTC AGTTTTGGGT CGTCACTGAG ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT 
GTTCAGCTAT TAAAAAAATT TATTAAGATA GCAGCCCACT GTAAGGAGTA TAAAAATCTG 
AATTCCTTTT TTGCCATCGT CATGGGACTA AGTAACGTTG CTGTGAGCCG CTTGGCACTA 
ACGTGGGAGA AACTGCCAAG CAAGTTCAAG AAGTTCTATG CGGAGTTTGA AAGTTTAATG 
GACCCTTCAA GGAACCACAG GGCCTACAGG CTGACAGTAG CTAAGCTGGA ACCTCCTCTC 
ATCCCCTTCA TGCCTTTGCT CATTAAAGAT ATGACATTTA CTCATGAGGG GAACAAGACG 
TTCATTGACA ATCTAGTAAA CTTTGAAAAA ATGCCTGTTG CTGAAATGCA CAAATGTTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( XM_017003197.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016858686.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X4, mRNA.

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CloneID	OHu88945
Clone ID Related Accession (Same CDS sequence)	XM_017003197.1
Accession Version	XM_017003197.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2550bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCTACA AGAAATATCG ACAGTATATG GCAGGACTTC TGGCTCCTCC TTATGGTGTT 
ATGGAAACGG GCTCTAACAA TGACAGGATT CCTGACAAGG AGAACGTCCC TTCAGAGAAG 
ATCCTCAGAG CTGGAAAAAT TTTACGAAAT GCCATTCTCT CTCGAGCACC TCACATGATA 
AGAGATAGAA AATACCACCT AAAGACATAC AGACAATGCT GTGTGGGAAC TGAACTGGTG 
GACTGGATGA TGCAGCAGAC ACCATGTGTT CACTCCCGGA CTCAAGCTGT TGGCATGTGG 
CAAGTCCTGT TAGAAGATGG TGTTCTCAAC CACGTGGACC AGGAGCACCA TTTCCAAGAC 
AAATATTTAT TCTATCGATT TCTGGATGAT GAGCACGAGG ATGCCCCTTT GCCTACTGAG 
GAGGAGAAGA AGGAGTGTGA TGAGGAGCTC CAGGACACCA TGCTGCTGCT GTCACAGATG 
GGCCCCGACG CCCACATGAG GATGATCCTT CGCAAACCAC CTGGCCAGAG GACTGTGGAT 
GACCTAGAGA TTATCTATGA GGAGCTTCTT CATATTAAAG CCTTATCCCA TCTTTCTACC 
ACAGTGAAAC GAGAGTTAGC AGGTGTTCTC ATTTTTGAGT CTCACGCCAA AGGAGGGACT 
GTGTTGTTTA ACCAGGGGGA AGAAGGTACC TCCTGGTACA TTATTCTAAA AGGATCAGTG 
AATGTAGTCA TTTACGGCAA GGGTGTGGTC TGCACCCTGC ATGAAGGAGA TGACTTCGGC 
AAGTTAGCAC TAGTGAATGA TGCCCCACGA GCTGCCTCTA TCGTCTTACG AGAAGATAAC 
TGCCATTTCT TAAGAGTAGA CAAGGAGGAT TTCAACCGGA TCCTAAGGGA CGTGGAGGCG 
AATACAGTCA GACTTAAAGA ACATGACCAA GATGTCTTGG TGCTGGAGAA GGTCCCAGCA 
GGGAACAGAG CTTCTAATCA AGGAAACTCA CAGCCTCAGC AAAAGTATAC TGTGATGTCA 
GGAACACCTG AAAAAATTTT AGAGCATTTT CTAGAAACAA TACGCCTTGA GGCAACTTTA 
AATGAAGCAA CAGATTCTGT TTTAAATGAC TTTATTATGA TGCACTGTGT TTTTATGCCA 
AATACCCAGC TTTGCCCGGC ACTGGTGGCC CACTACCACG CACAGCCTTC ACAAGGTACA 
GAACAGGAGA AAATGGATTA TGCCCTCAAC AATAAGAGGC GAGTCATCCG CCTGGTTCTA 
CAGTGGGCTG CCATGTATGG AGACCTCCTG CAAGAGGATG ACGTGTCTAT GGCCTTCCTG 
GAGGAGTTTT ATGTATCTGT ATCAGATGAT GCCCGGATGA TTGCTGCCCT CAAGGAGCAA 
CTGCCAGAGT TGGAGAAGAT TGTCAAGCAA ATCTCAGAAG ATGCAAAGGC ACCACAAAAG 
AAGCACAAGG TTCTTTTGCA ACAGTTCAAT ACGGGCGATG AGAGAGCCCA GAAGCGCCAG 
CCTATCCGCG GCTCTGATGA AGTTCTGTTT AAGGTCTATT GCATGGACCA CACCTACACA 
ACCATTCGGG TGCCAGTGGC CACTTCGGTG AAGGAAGTCA TCAGTGCAGT TGCCGACAAG 
CTGGGCTCCG GGGAGGGCCT GATCATAGTC AAGATGAGTT CCGGAGGAGA AAAGGTGGTG 
CTCAAACCTA ATGATGTTTC AGTATTTACG ACGCTCACCA TTAATGGACG CCTGTTTGCT 
TGCCCGCGAG AGCAATTCGA TTCACTGACT CCCTTACCAG AACAGGAAGG CCCAACTGTT 
GGAACAGTGG GAACTTTTGA ACTGATGAGC TCCAAAGATT TAGCATACCA GATGACAATT 
TATGATTGGG AACTCTTCAA CTGCGTGCAT GAGCTGGAGC TAATCTATCA CACATTTGGA 
AGGCATAATT TTAAAAAGAC CACAGCAAAC TTGGATTTGT TCCTGAGGAG ATTTAATGAA 
ATTCAGTTTT GGGTCGTCAC TGAGATCTGC CTTTGTTCTC AGCTCAGCAA GCGTGTTCAG 
CTATTAAAAA AATTTATTAA GATAGCAGCC CACTGTAAGG AGTATAAAAA TCTGAATTCC 
TTTTTTGCCA TCGTCATGGG ACTAAGTAAC GTTGCTGTGA GCCGCTTGGC ACTAACGTGG 
GAGAAACTGC CAAGCAAGTT CAAGAAGTTC TATGCGGAGT TTGAAAGTTT AATGGACCCT 
TCAAGGAACC ACAGGGCCTA CAGGCTGACA GTAGCTAAGC TGGAACCTCC TCTCATCCCC 
TTCATGCCTT TGCTCATTAA AGATATGACA TTTACTCATG AGGGGAACAA GACGTTCATT 
GACAATCTAG TAAACTTTGA AAAAATGCGC ATGATTGCAA ATACGGCCAG AACAGTGAGA 
TACTACAGGA GCCAACCCTT CAATCCTGAT GCAGCTCAAG CTAATAAGAA CCATCAGGAT 
GTCCGGAGTT ATGTACGGCA ATTAAATGTG ATTGACAACC AGAGAACTTT ATCACAGATG 
TCACACAGAT TAGAGCCTCG TCGACCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016858686.1
CDS	190..2739
Translation	MLYKKYRQYMAGLLAPPYGVMETGSNNDRIPDKENVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	XM_017003197.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017003197.1

ORF Insert Sequence:

ATGCTCTACA AGAAATATCG ACAGTATATG GCAGGACTTC TGGCTCCTCC TTATGGTGTT 
ATGGAAACGG GCTCTAACAA TGACAGGATT CCTGACAAGG AGAACGTCCC TTCAGAGAAG 
ATCCTCAGAG CTGGAAAAAT TTTACGAAAT GCCATTCTCT CTCGAGCACC TCACATGATA 
AGAGATAGAA AATACCACCT AAAGACATAC AGACAATGCT GTGTGGGAAC TGAACTGGTG 
GACTGGATGA TGCAGCAGAC ACCATGTGTT CACTCCCGGA CTCAAGCTGT TGGCATGTGG 
CAAGTCCTGT TAGAAGATGG TGTTCTCAAC CACGTGGACC AGGAGCACCA TTTCCAAGAC 
AAATATTTAT TCTATCGATT TCTGGATGAT GAGCACGAGG ATGCCCCTTT GCCTACTGAG 
GAGGAGAAGA AGGAGTGTGA TGAGGAGCTC CAGGACACCA TGCTGCTGCT GTCACAGATG 
GGCCCCGACG CCCACATGAG GATGATCCTT CGCAAACCAC CTGGCCAGAG GACTGTGGAT 
GACCTAGAGA TTATCTATGA GGAGCTTCTT CATATTAAAG CCTTATCCCA TCTTTCTACC 
ACAGTGAAAC GAGAGTTAGC AGGTGTTCTC ATTTTTGAGT CTCACGCCAA AGGAGGGACT 
GTGTTGTTTA ACCAGGGGGA AGAAGGTACC TCCTGGTACA TTATTCTAAA AGGATCAGTG 
AATGTAGTCA TTTACGGCAA GGGTGTGGTC TGCACCCTGC ATGAAGGAGA TGACTTCGGC 
AAGTTAGCAC TAGTGAATGA TGCCCCACGA GCTGCCTCTA TCGTCTTACG AGAAGATAAC 
TGCCATTTCT TAAGAGTAGA CAAGGAGGAT TTCAACCGGA TCCTAAGGGA CGTGGAGGCG 
AATACAGTCA GACTTAAAGA ACATGACCAA GATGTCTTGG TGCTGGAGAA GGTCCCAGCA 
GGGAACAGAG CTTCTAATCA AGGAAACTCA CAGCCTCAGC AAAAGTATAC TGTGATGTCA 
GGAACACCTG AAAAAATTTT AGAGCATTTT CTAGAAACAA TACGCCTTGA GGCAACTTTA 
AATGAAGCAA CAGATTCTGT TTTAAATGAC TTTATTATGA TGCACTGTGT TTTTATGCCA 
AATACCCAGC TTTGCCCGGC ACTGGTGGCC CACTACCACG CACAGCCTTC ACAAGGTACA 
GAACAGGAGA AAATGGATTA TGCCCTCAAC AATAAGAGGC GAGTCATCCG CCTGGTTCTA 
CAGTGGGCTG CCATGTATGG AGACCTCCTG CAAGAGGATG ACGTGTCTAT GGCCTTCCTG 
GAGGAGTTTT ATGTATCTGT ATCAGATGAT GCCCGGATGA TTGCTGCCCT CAAGGAGCAA 
CTGCCAGAGT TGGAGAAGAT TGTCAAGCAA ATCTCAGAAG ATGCAAAGGC ACCACAAAAG 
AAGCACAAGG TTCTTTTGCA ACAGTTCAAT ACGGGCGATG AGAGAGCCCA GAAGCGCCAG 
CCTATCCGCG GCTCTGATGA AGTTCTGTTT AAGGTCTATT GCATGGACCA CACCTACACA 
ACCATTCGGG TGCCAGTGGC CACTTCGGTG AAGGAAGTCA TCAGTGCAGT TGCCGACAAG 
CTGGGCTCCG GGGAGGGCCT GATCATAGTC AAGATGAGTT CCGGAGGAGA AAAGGTGGTG 
CTCAAACCTA ATGATGTTTC AGTATTTACG ACGCTCACCA TTAATGGACG CCTGTTTGCT 
TGCCCGCGAG AGCAATTCGA TTCACTGACT CCCTTACCAG AACAGGAAGG CCCAACTGTT 
GGAACAGTGG GAACTTTTGA ACTGATGAGC TCCAAAGATT TAGCATACCA GATGACAATT 
TATGATTGGG AACTCTTCAA CTGCGTGCAT GAGCTGGAGC TAATCTATCA CACATTTGGA 
AGGCATAATT TTAAAAAGAC CACAGCAAAC TTGGATTTGT TCCTGAGGAG ATTTAATGAA 
ATTCAGTTTT GGGTCGTCAC TGAGATCTGC CTTTGTTCTC AGCTCAGCAA GCGTGTTCAG 
CTATTAAAAA AATTTATTAA GATAGCAGCC CACTGTAAGG AGTATAAAAA TCTGAATTCC 
TTTTTTGCCA TCGTCATGGG ACTAAGTAAC GTTGCTGTGA GCCGCTTGGC ACTAACGTGG 
GAGAAACTGC CAAGCAAGTT CAAGAAGTTC TATGCGGAGT TTGAAAGTTT AATGGACCCT 
TCAAGGAACC ACAGGGCCTA CAGGCTGACA GTAGCTAAGC TGGAACCTCC TCTCATCCCC 
TTCATGCCTT TGCTCATTAA AGATATGACA TTTACTCATG AGGGGAACAA GACGTTCATT 
GACAATCTAG TAAACTTTGA AAAAATGCGC ATGATTGCAA ATACGGCCAG AACAGTGAGA 
TACTACAGGA GCCAACCCTT CAATCCTGAT GCAGCTCAAG CTAATAAGAA CCATCAGGAT 
GTCCGGAGTT ATGTACGGCA ATTAAATGTG ATTGACAACC AGAGAACTTT ATCACAGATG 
TCACACAGAT TAGAGCCTCG TCGACCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001375864.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001362793.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu109026
Clone ID Related Accession (Same CDS sequence)	NM_001375864.1
Accession Version	NM_001375864.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3006bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform f
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018712.5, AC009484.3, AC104086.6 and AC019046.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.46521.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length.

ATGCATACCC TTTCCGGCTA TTCAGACCTT GCGGGACCAC TGGAGCGATC CAGCGAAGAT 
GTGGATATAA TCTTCACTCG ACTGAAAGAA GTTAAAGCTT TTGAGAAATT TCACCCAAAT 
CTCCTTCATC AGATTTGCTT ATGTGGTTAT TATGAGAATC TGGAAAAGGG AATAACATTA 
TTTCGCCAGG GTGATATTGG AACAAACTGG TATGCTGTCC TGGCAGGGTC TTTGGATGTT 
AAAGTATCTG AGACCAGCAG TCACCAGGAT GCTGTGACCA TCTGTACCCT GGGAATTGGG 
ACGGCCTTTG GAGAGTCCAT TCTGGACAAC ACACCCCGCC ATGCAACCAT CGTTACCAGG 
GAGAGCAGTG AACTGCTCCG CATCGAGCAG AAGGACTTCA AGGCACTATG GGAGAAATAT 
CGACAGTATA TGGCAGGACT TCTGGCTCCT CCTTATGGTG TTATGGAAAC GGGCTCTAAC 
AATGACAGGA TTCCTGACAA GGAGAACACA CCTCTCATTG AACCTCACGT TCCTCTTCGT 
CCTGCTAACA CCATTACCAA GGTCCCTTCA GAGAAGATCC TCAGAGCTGG AAAAATTTTA 
CGAAATGCCA TTCTCTCTCG AGCACCTCAC ATGATAAGAG ATAGAAAATA CCACCTAAAG 
ACATACAGAC AATGCTGTGT GGGAACTGAA CTGGTGGACT GGATGATGCA GCAGACACCA 
TGTGTTCACT CCCGGACTCA AGCTGTTGGC ATGTGGCAAG TCCTGTTAGA AGATGGTGTT 
CTCAACCACG TGGACCAGGA GCACCATTTC CAAGACAAAT ATTTATTCTA TCGATTTCTG 
GATGATGAGC ACGAGGATGC CCCTTTGCCT ACTGAGGAGG AGAAGAAGGA GTGTGATGAG 
GAGCTCCAGG ACACCATGCT GCTGCTGTCA CAGATGGGCC CCGACGCCCA CATGAGGATG 
ATCCTTCGCA AACCACCTGG CCAGAGGACT GTGGATGACC TAGAGATTAT CTATGAGGAG 
CTTCTTCATA TTAAAGCCTT ATCCCATCTT TCTACCACAG TGAAACGAGA GTTAGCAGGT 
GTTCTCATTT TTGAGTCTCA CGCCAAAGGA GGGACTGTGT TGTTTAACCA GGGGGAAGAA 
GGTACCTCCT GGTACATTAT TCTAAAAGGA TCAGTGAATG TAGTCATTTA CGGCAAGGGT 
GTGGTCTGCA CCCTGCATGA AGGAGATGAC TTCGGCAAGT TAGCACTAGT GAATGATGCC 
CCACGAGCTG CCTCTATCGT CTTACGAGAA GATAACTGCC ATTTCTTAAG AGTAGACAAG 
GAGGATTTCA ACCGGATCCT AAGGGACGTG GAGGCGAATA CAGTCAGACT TAAAGAACAT 
GACCAAGATG TCTTGGTGCT GGAGAAGGTC CCAGCAGGGA ACAGAGCTTC TAATCAAGGA 
AACTCACAGC CTCAGCAAAA GTATACTGTG ATGTCAGGAA CACCTGAAAA AATTTTAGAG 
CATTTTCTAG AAACAATACG CCTTGAGGCA ACTTTAAATG AAGCAACAGA TTCTGTTTTA 
AATGACTTTA TTATGATGCA CTGTGTTTTT ATGCCAAATA CCCAGCTTTG CCCGGCACTG 
GTGGCCCACT ACCACGCACA GCCTTCACAA GGTACAGAAC AGGAGAAAAT GGATTATGCC 
CTCAACAATA AGAGGCGAGT CATCCGCCTG GTTCTACAGT GGGCTGCCAT GTATGGAGAC 
CTCCTGCAAG AGGATGACGT GTCTATGGCC TTCCTGGAGG AGTTTTATGT ATCTGTATCA 
GATGATGCCC GGATGATTGC TGCCCTCAAG GAGCAACTGC CAGAGTTGGA GAAGATTGTC 
AAGCAAATCT CAGAAGATGC AAAGGCACCA CAAAAGAAGC ACAAGGTTCT TTTGCAACAG 
TTCAATACGG GCGATGAGAG AGCCCAGAAG CGCCAGCCTA TCCGCGGCTC TGATGAAGTT 
CTGTTTAAGG TCTATTGCAT GGACCACACC TACACAACCA TTCGGGTGCC AGTGGCCACT 
TCGGTGAAGG AAGTCATCAG TGCAGTTGCC GACAAGCTGG GCTCCGGGGA GGGCCTGATC 
ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG GTGGTGCTCA AACCTAATGA TGTTTCAGTA 
TTTACGACGC TCACCATTAA TGGACGCCTG TTTGCTTGCC CGCGAGAGCA ATTCGATTCA 
CTGACTCCCT TACCAGAACA GGAAGGCCCA ACTGTTGGAA CAGTGGGAAC TTTTGAACTG 
ATGAGCTCCA AAGATTTAGC ATACCAGATG ACAATTTATG ATTGGGAACT CTTCAACTGC 
GTGCATGAGC TGGAGCTAAT CTATCACACA TTTGGAAGGC ATAATTTTAA AAAGACCACA 
GCAAACTTGG ATTTGTTCCT GAGGAGATTT AATGAAATTC AGTTTTGGGT CGTCACTGAG 
ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT GTTCAGCTAT TAAAAAAATT TATTAAGATA 
GCAGCCCACT GTAAGGAGTA TAAAAATCTG AATTCCTTTT TTGCCATCGT CATGGGACTA 
AGTAACGTTG CTGTGAGCCG CTTGGCACTA ACGTGGGAGA AACTGCCAAG CAAGTTCAAG 
AAGTTCTATG CGGAGTTTGA AAGTTTAATG GACCCTTCAA GGAACCACAG GGCCTACAGG 
CTGACAGTAG CTAAGCTGGA ACCTCCTCTC ATCCCCTTCA TGCCTTTGCT CATTAAAGAT 
ATGACATTTA CTCATGAGGG GAACAAGACG TTCATTGACA ATCTAGTAAA CTTTGAAAAA 
ATGCGCATGA TTGCAAATAC GGCCAGAACA GTGAGATACT ACAGGAGCCA ACCCTTCAAT 
CCTGATGCAG CTCAAGCTAA TAAGAACCAT CAGGATGTCC GGAGTTATGT ACGGCAATTA 
AATGTGATTG ACAACCAGAG AACTTTATCA CAGATGTCAC ACAGATTAGA GCCTCGTCGA 
CCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001362793.1
CDS	547..3552
Translation	MHTLSGYSDLAGPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	NM_001375864.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001375864.1

ORF Insert Sequence:

ATGCATACCC TTTCCGGCTA TTCAGACCTT GCGGGACCAC TGGAGCGATC CAGCGAAGAT 
GTGGATATAA TCTTCACTCG ACTGAAAGAA GTTAAAGCTT TTGAGAAATT TCACCCAAAT 
CTCCTTCATC AGATTTGCTT ATGTGGTTAT TATGAGAATC TGGAAAAGGG AATAACATTA 
TTTCGCCAGG GTGATATTGG AACAAACTGG TATGCTGTCC TGGCAGGGTC TTTGGATGTT 
AAAGTATCTG AGACCAGCAG TCACCAGGAT GCTGTGACCA TCTGTACCCT GGGAATTGGG 
ACGGCCTTTG GAGAGTCCAT TCTGGACAAC ACACCCCGCC ATGCAACCAT CGTTACCAGG 
GAGAGCAGTG AACTGCTCCG CATCGAGCAG AAGGACTTCA AGGCACTATG GGAGAAATAT 
CGACAGTATA TGGCAGGACT TCTGGCTCCT CCTTATGGTG TTATGGAAAC GGGCTCTAAC 
AATGACAGGA TTCCTGACAA GGAGAACACA CCTCTCATTG AACCTCACGT TCCTCTTCGT 
CCTGCTAACA CCATTACCAA GGTCCCTTCA GAGAAGATCC TCAGAGCTGG AAAAATTTTA 
CGAAATGCCA TTCTCTCTCG AGCACCTCAC ATGATAAGAG ATAGAAAATA CCACCTAAAG 
ACATACAGAC AATGCTGTGT GGGAACTGAA CTGGTGGACT GGATGATGCA GCAGACACCA 
TGTGTTCACT CCCGGACTCA AGCTGTTGGC ATGTGGCAAG TCCTGTTAGA AGATGGTGTT 
CTCAACCACG TGGACCAGGA GCACCATTTC CAAGACAAAT ATTTATTCTA TCGATTTCTG 
GATGATGAGC ACGAGGATGC CCCTTTGCCT ACTGAGGAGG AGAAGAAGGA GTGTGATGAG 
GAGCTCCAGG ACACCATGCT GCTGCTGTCA CAGATGGGCC CCGACGCCCA CATGAGGATG 
ATCCTTCGCA AACCACCTGG CCAGAGGACT GTGGATGACC TAGAGATTAT CTATGAGGAG 
CTTCTTCATA TTAAAGCCTT ATCCCATCTT TCTACCACAG TGAAACGAGA GTTAGCAGGT 
GTTCTCATTT TTGAGTCTCA CGCCAAAGGA GGGACTGTGT TGTTTAACCA GGGGGAAGAA 
GGTACCTCCT GGTACATTAT TCTAAAAGGA TCAGTGAATG TAGTCATTTA CGGCAAGGGT 
GTGGTCTGCA CCCTGCATGA AGGAGATGAC TTCGGCAAGT TAGCACTAGT GAATGATGCC 
CCACGAGCTG CCTCTATCGT CTTACGAGAA GATAACTGCC ATTTCTTAAG AGTAGACAAG 
GAGGATTTCA ACCGGATCCT AAGGGACGTG GAGGCGAATA CAGTCAGACT TAAAGAACAT 
GACCAAGATG TCTTGGTGCT GGAGAAGGTC CCAGCAGGGA ACAGAGCTTC TAATCAAGGA 
AACTCACAGC CTCAGCAAAA GTATACTGTG ATGTCAGGAA CACCTGAAAA AATTTTAGAG 
CATTTTCTAG AAACAATACG CCTTGAGGCA ACTTTAAATG AAGCAACAGA TTCTGTTTTA 
AATGACTTTA TTATGATGCA CTGTGTTTTT ATGCCAAATA CCCAGCTTTG CCCGGCACTG 
GTGGCCCACT ACCACGCACA GCCTTCACAA GGTACAGAAC AGGAGAAAAT GGATTATGCC 
CTCAACAATA AGAGGCGAGT CATCCGCCTG GTTCTACAGT GGGCTGCCAT GTATGGAGAC 
CTCCTGCAAG AGGATGACGT GTCTATGGCC TTCCTGGAGG AGTTTTATGT ATCTGTATCA 
GATGATGCCC GGATGATTGC TGCCCTCAAG GAGCAACTGC CAGAGTTGGA GAAGATTGTC 
AAGCAAATCT CAGAAGATGC AAAGGCACCA CAAAAGAAGC ACAAGGTTCT TTTGCAACAG 
TTCAATACGG GCGATGAGAG AGCCCAGAAG CGCCAGCCTA TCCGCGGCTC TGATGAAGTT 
CTGTTTAAGG TCTATTGCAT GGACCACACC TACACAACCA TTCGGGTGCC AGTGGCCACT 
TCGGTGAAGG AAGTCATCAG TGCAGTTGCC GACAAGCTGG GCTCCGGGGA GGGCCTGATC 
ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG GTGGTGCTCA AACCTAATGA TGTTTCAGTA 
TTTACGACGC TCACCATTAA TGGACGCCTG TTTGCTTGCC CGCGAGAGCA ATTCGATTCA 
CTGACTCCCT TACCAGAACA GGAAGGCCCA ACTGTTGGAA CAGTGGGAAC TTTTGAACTG 
ATGAGCTCCA AAGATTTAGC ATACCAGATG ACAATTTATG ATTGGGAACT CTTCAACTGC 
GTGCATGAGC TGGAGCTAAT CTATCACACA TTTGGAAGGC ATAATTTTAA AAAGACCACA 
GCAAACTTGG ATTTGTTCCT GAGGAGATTT AATGAAATTC AGTTTTGGGT CGTCACTGAG 
ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT GTTCAGCTAT TAAAAAAATT TATTAAGATA 
GCAGCCCACT GTAAGGAGTA TAAAAATCTG AATTCCTTTT TTGCCATCGT CATGGGACTA 
AGTAACGTTG CTGTGAGCCG CTTGGCACTA ACGTGGGAGA AACTGCCAAG CAAGTTCAAG 
AAGTTCTATG CGGAGTTTGA AAGTTTAATG GACCCTTCAA GGAACCACAG GGCCTACAGG 
CTGACAGTAG CTAAGCTGGA ACCTCCTCTC ATCCCCTTCA TGCCTTTGCT CATTAAAGAT 
ATGACATTTA CTCATGAGGG GAACAAGACG TTCATTGACA ATCTAGTAAA CTTTGAAAAA 
ATGCGCATGA TTGCAAATAC GGCCAGAACA GTGAGATACT ACAGGAGCCA ACCCTTCAAT 
CCTGATGCAG CTCAAGCTAA TAAGAACCAT CAGGATGTCC GGAGTTATGT ACGGCAATTA 
AATGTGATTG ACAACCAGAG AACTTTATCA CAGATGTCAC ACAGATTAGA GCCTCGTCGA 
CCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_001375865.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001362794.1 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 7, mRNA.

Price & Availability↑

CloneID	OHu109031
Clone ID Related Accession (Same CDS sequence)	NM_001375865.1
Accession Version	NM_001375865.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3003bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform g
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018712.5, AC009484.3, AC104086.6 and AC019046.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.283579.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGTATTT 
ACGACGCTCA CCATTAATGG ACGCCTGTTT GCTTGCCCGC GAGAGCAATT CGATTCACTG 
ACTCCCTTAC CAGAACAGGA AGGCCCAACT GTTGGAACAG TGGGAACTTT TGAACTGATG 
AGCTCCAAAG ATTTAGCATA CCAGATGACA ATTTATGATT GGGAACTCTT CAACTGCGTG 
CATGAGCTGG AGCTAATCTA TCACACATTT GGAAGGCATA ATTTTAAAAA GACCACAGCA 
AACTTGGATT TGTTCCTGAG GAGATTTAAT GAAATTCAGT TTTGGGTCGT CACTGAGATC 
TGCCTTTGTT CTCAGCTCAG CAAGCGTGTT CAGCTATTAA AAAAATTTAT TAAGATAGCA 
GCCCACTGTA AGGAGTATAA AAATCTGAAT TCCTTTTTTG CCATCGTCAT GGGACTAAGT 
AACGTTGCTG TGAGCCGCTT GGCACTAACG TGGGAGAAAC TGCCAAGCAA GTTCAAGAAG 
TTCTATGCGG AGTTTGAAAG TTTAATGGAC CCTTCAAGGA ACCACAGGGC CTACAGGCTG 
ACAGTAGCTA AGCTGGAACC TCCTCTCATC CCCTTCATGC CTTTGCTCAT TAAAGATATG 
ACATTTACTC ATGAGGGGAA CAAGACGTTC ATTGACAATC TAGTAAACTT TGAAAAAATG 
CGCATGATTG CAAATACGGC CAGAACAGTG AGATACTACA GGAGCCAACC CTTCAATCCT 
GATGCAGCTC AAGCTAATAA GAACCATCAG GATGTCCGGA GTTATGTACG GCAATTAAAT 
GTGATTGACA ACCAGAGAAC TTTATCACAG ATGTCACACA GATTAGAGCC TCGTCGACCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001362794.1
CDS	140..3142
Translation	MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	NM_001375865.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001375865.1

ORF Insert Sequence:

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGTATTT 
ACGACGCTCA CCATTAATGG ACGCCTGTTT GCTTGCCCGC GAGAGCAATT CGATTCACTG 
ACTCCCTTAC CAGAACAGGA AGGCCCAACT GTTGGAACAG TGGGAACTTT TGAACTGATG 
AGCTCCAAAG ATTTAGCATA CCAGATGACA ATTTATGATT GGGAACTCTT CAACTGCGTG 
CATGAGCTGG AGCTAATCTA TCACACATTT GGAAGGCATA ATTTTAAAAA GACCACAGCA 
AACTTGGATT TGTTCCTGAG GAGATTTAAT GAAATTCAGT TTTGGGTCGT CACTGAGATC 
TGCCTTTGTT CTCAGCTCAG CAAGCGTGTT CAGCTATTAA AAAAATTTAT TAAGATAGCA 
GCCCACTGTA AGGAGTATAA AAATCTGAAT TCCTTTTTTG CCATCGTCAT GGGACTAAGT 
AACGTTGCTG TGAGCCGCTT GGCACTAACG TGGGAGAAAC TGCCAAGCAA GTTCAAGAAG 
TTCTATGCGG AGTTTGAAAG TTTAATGGAC CCTTCAAGGA ACCACAGGGC CTACAGGCTG 
ACAGTAGCTA AGCTGGAACC TCCTCTCATC CCCTTCATGC CTTTGCTCAT TAAAGATATG 
ACATTTACTC ATGAGGGGAA CAAGACGTTC ATTGACAATC TAGTAAACTT TGAAAAAATG 
CGCATGATTG CAAATACGGC CAGAACAGTG AGATACTACA GGAGCCAACC CTTCAATCCT 
GATGCAGCTC AAGCTAATAA GAACCATCAG GATGTCCGGA GTTATGTACG GCAATTAAAT 
GTGATTGACA ACCAGAGAAC TTTATCACAG ATGTCACACA GATTAGAGCC TCGTCGACCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_007023.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_008954.2 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17245
Clone ID Related Accession (Same CDS sequence)	NM_007023.3 , NM_007023.4
Accession Version	NM_007023.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3036bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB471672.1, BI546558.1, AB027471.1, BC024004.2 and BQ184791.1. On Aug 10, 2007 this sequence version replaced NM_007023.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.261752.1, SRR1660805.245272.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145122, SAMEA2145240 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG 
GTGGTGCTCA AACCTAATGA TGTTTCAGTA TTTACGACGC TCACCATTAA TGGACGCCTG 
TTTGCTTGCC CGCGAGAGCA ATTCGATTCA CTGACTCCCT TACCAGAACA GGAAGGCCCA 
ACTGTTGGAA CAGTGGGAAC TTTTGAACTG ATGAGCTCCA AAGATTTAGC ATACCAGATG 
ACAATTTATG ATTGGGAACT CTTCAACTGC GTGCATGAGC TGGAGCTAAT CTATCACACA 
TTTGGAAGGC ATAATTTTAA AAAGACCACA GCAAACTTGG ATTTGTTCCT GAGGAGATTT 
AATGAAATTC AGTTTTGGGT CGTCACTGAG ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT 
GTTCAGCTAT TAAAAAAATT TATTAAGATA GCAGCCCACT GTAAGGAGTA TAAAAATCTG 
AATTCCTTTT TTGCCATCGT CATGGGACTA AGTAACGTTG CTGTGAGCCG CTTGGCACTA 
ACGTGGGAGA AACTGCCAAG CAAGTTCAAG AAGTTCTATG CGGAGTTTGA AAGTTTAATG 
GACCCTTCAA GGAACCACAG GGCCTACAGG CTGACAGTAG CTAAGCTGGA ACCTCCTCTC 
ATCCCCTTCA TGCCTTTGCT CATTAAAGAT ATGACATTTA CTCATGAGGG GAACAAGACG 
TTCATTGACA ATCTAGTAAA CTTTGAAAAA ATGCGCATGA TTGCAAATAC GGCCAGAACA 
GTGAGATACT ACAGGAGCCA ACCCTTCAAT CCTGATGCAG CTCAAGCTAA TAAGAACCAT 
CAGGATGTCC GGAGTTATGT ACGGCAATTA AATGTGATTG ACAACCAGAG AACTTTATCA 
CAGATGTCAC ACAGATTAGA GCCTCGTCGA CCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_008954.2
CDS	188..3223
Translation	MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	NM_007023.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007023.3

ORF Insert Sequence:

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG 
GTGGTGCTCA AACCTAATGA TGTTTCAGTA TTTACGACGC TCACCATTAA TGGACGCCTG 
TTTGCTTGCC CGCGAGAGCA ATTCGATTCA CTGACTCCCT TACCAGAACA GGAAGGCCCA 
ACTGTTGGAA CAGTGGGAAC TTTTGAACTG ATGAGCTCCA AAGATTTAGC ATACCAGATG 
ACAATTTATG ATTGGGAACT CTTCAACTGC GTGCATGAGC TGGAGCTAAT CTATCACACA 
TTTGGAAGGC ATAATTTTAA AAAGACCACA GCAAACTTGG ATTTGTTCCT GAGGAGATTT 
AATGAAATTC AGTTTTGGGT CGTCACTGAG ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT 
GTTCAGCTAT TAAAAAAATT TATTAAGATA GCAGCCCACT GTAAGGAGTA TAAAAATCTG 
AATTCCTTTT TTGCCATCGT CATGGGACTA AGTAACGTTG CTGTGAGCCG CTTGGCACTA 
ACGTGGGAGA AACTGCCAAG CAAGTTCAAG AAGTTCTATG CGGAGTTTGA AAGTTTAATG 
GACCCTTCAA GGAACCACAG GGCCTACAGG CTGACAGTAG CTAAGCTGGA ACCTCCTCTC 
ATCCCCTTCA TGCCTTTGCT CATTAAAGAT ATGACATTTA CTCATGAGGG GAACAAGACG 
TTCATTGACA ATCTAGTAAA CTTTGAAAAA ATGCGCATGA TTGCAAATAC GGCCAGAACA 
GTGAGATACT ACAGGAGCCA ACCCTTCAAT CCTGATGCAG CTCAAGCTAA TAAGAACCAT 
CAGGATGTCC GGAGTTATGT ACGGCAATTA AATGTGATTG ACAACCAGAG AACTTTATCA 
CAGATGTCAC ACAGATTAGA GCCTCGTCGA CCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAPGEF4 ( NM_007023.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_008954.2 Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 1, mRNA.

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CloneID	OHu17245
Clone ID Related Accession (Same CDS sequence)	NM_007023.3 , NM_007023.4
Accession Version	NM_007023.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3036bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-22
Organism	Homo sapiens(human)
Product	rap guanine nucleotide exchange factor 4 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018712.5, AC009484.3, AC104086.6 and AC019046.4. On Nov 23, 2018 this sequence version replaced NM_007023.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.237474.1, SRR1803613.166907.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145122, SAMEA2145240 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000397081.8/ ENSP00000380271.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG 
GTGGTGCTCA AACCTAATGA TGTTTCAGTA TTTACGACGC TCACCATTAA TGGACGCCTG 
TTTGCTTGCC CGCGAGAGCA ATTCGATTCA CTGACTCCCT TACCAGAACA GGAAGGCCCA 
ACTGTTGGAA CAGTGGGAAC TTTTGAACTG ATGAGCTCCA AAGATTTAGC ATACCAGATG 
ACAATTTATG ATTGGGAACT CTTCAACTGC GTGCATGAGC TGGAGCTAAT CTATCACACA 
TTTGGAAGGC ATAATTTTAA AAAGACCACA GCAAACTTGG ATTTGTTCCT GAGGAGATTT 
AATGAAATTC AGTTTTGGGT CGTCACTGAG ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT 
GTTCAGCTAT TAAAAAAATT TATTAAGATA GCAGCCCACT GTAAGGAGTA TAAAAATCTG 
AATTCCTTTT TTGCCATCGT CATGGGACTA AGTAACGTTG CTGTGAGCCG CTTGGCACTA 
ACGTGGGAGA AACTGCCAAG CAAGTTCAAG AAGTTCTATG CGGAGTTTGA AAGTTTAATG 
GACCCTTCAA GGAACCACAG GGCCTACAGG CTGACAGTAG CTAAGCTGGA ACCTCCTCTC 
ATCCCCTTCA TGCCTTTGCT CATTAAAGAT ATGACATTTA CTCATGAGGG GAACAAGACG 
TTCATTGACA ATCTAGTAAA CTTTGAAAAA ATGCGCATGA TTGCAAATAC GGCCAGAACA 
GTGAGATACT ACAGGAGCCA ACCCTTCAAT CCTGATGCAG CTCAAGCTAA TAAGAACCAT 
CAGGATGTCC GGAGTTATGT ACGGCAATTA AATGTGATTG ACAACCAGAG AACTTTATCA 
CAGATGTCAC ACAGATTAGA GCCTCGTCGA CCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_008954.2
CDS	140..3175
Translation	MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP

Target ORF information:

RefSeq Version	NM_007023.4
Organism	Homo sapiens(human)
Definition	Homo sapiens Rap guanine nucleotide exchange factor 4 (RAPGEF4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007023.4

ORF Insert Sequence:

ATGGTCGCTG CGCACGCTGC CCATTCTTCC TCCTCTGCCG AGTGGATCGC CTGCCTGGAT 
AAAAGACCAC TGGAGCGATC CAGCGAAGAT GTGGATATAA TCTTCACTCG ACTGAAAGAA 
GTTAAAGCTT TTGAGAAATT TCACCCAAAT CTCCTTCATC AGATTTGCTT ATGTGGTTAT 
TATGAGAATC TGGAAAAGGG AATAACATTA TTTCGCCAGG GTGATATTGG AACAAACTGG 
TATGCTGTCC TGGCAGGGTC TTTGGATGTT AAAGTATCTG AGACCAGCAG TCACCAGGAT 
GCTGTGACCA TCTGTACCCT GGGAATTGGG ACGGCCTTTG GAGAGTCCAT TCTGGACAAC 
ACACCCCGCC ATGCAACCAT CGTTACCAGG GAGAGCAGTG AACTGCTCCG CATCGAGCAG 
AAGGACTTCA AGGCACTATG GGAGAAATAT CGACAGTATA TGGCAGGACT TCTGGCTCCT 
CCTTATGGTG TTATGGAAAC GGGCTCTAAC AATGACAGGA TTCCTGACAA GGAGAACACA 
CCTCTCATTG AACCTCACGT TCCTCTTCGT CCTGCTAACA CCATTACCAA GGTCCCTTCA 
GAGAAGATCC TCAGAGCTGG AAAAATTTTA CGAAATGCCA TTCTCTCTCG AGCACCTCAC 
ATGATAAGAG ATAGAAAATA CCACCTAAAG ACATACAGAC AATGCTGTGT GGGAACTGAA 
CTGGTGGACT GGATGATGCA GCAGACACCA TGTGTTCACT CCCGGACTCA AGCTGTTGGC 
ATGTGGCAAG TCCTGTTAGA AGATGGTGTT CTCAACCACG TGGACCAGGA GCACCATTTC 
CAAGACAAAT ATTTATTCTA TCGATTTCTG GATGATGAGC ACGAGGATGC CCCTTTGCCT 
ACTGAGGAGG AGAAGAAGGA GTGTGATGAG GAGCTCCAGG ACACCATGCT GCTGCTGTCA 
CAGATGGGCC CCGACGCCCA CATGAGGATG ATCCTTCGCA AACCACCTGG CCAGAGGACT 
GTGGATGACC TAGAGATTAT CTATGAGGAG CTTCTTCATA TTAAAGCCTT ATCCCATCTT 
TCTACCACAG TGAAACGAGA GTTAGCAGGT GTTCTCATTT TTGAGTCTCA CGCCAAAGGA 
GGGACTGTGT TGTTTAACCA GGGGGAAGAA GGTACCTCCT GGTACATTAT TCTAAAAGGA 
TCAGTGAATG TAGTCATTTA CGGCAAGGGT GTGGTCTGCA CCCTGCATGA AGGAGATGAC 
TTCGGCAAGT TAGCACTAGT GAATGATGCC CCACGAGCTG CCTCTATCGT CTTACGAGAA 
GATAACTGCC ATTTCTTAAG AGTAGACAAG GAGGATTTCA ACCGGATCCT AAGGGACGTG 
GAGGCGAATA CAGTCAGACT TAAAGAACAT GACCAAGATG TCTTGGTGCT GGAGAAGGTC 
CCAGCAGGGA ACAGAGCTTC TAATCAAGGA AACTCACAGC CTCAGCAAAA GTATACTGTG 
ATGTCAGGAA CACCTGAAAA AATTTTAGAG CATTTTCTAG AAACAATACG CCTTGAGGCA 
ACTTTAAATG AAGCAACAGA TTCTGTTTTA AATGACTTTA TTATGATGCA CTGTGTTTTT 
ATGCCAAATA CCCAGCTTTG CCCGGCACTG GTGGCCCACT ACCACGCACA GCCTTCACAA 
GGTACAGAAC AGGAGAAAAT GGATTATGCC CTCAACAATA AGAGGCGAGT CATCCGCCTG 
GTTCTACAGT GGGCTGCCAT GTATGGAGAC CTCCTGCAAG AGGATGACGT GTCTATGGCC 
TTCCTGGAGG AGTTTTATGT ATCTGTATCA GATGATGCCC GGATGATTGC TGCCCTCAAG 
GAGCAACTGC CAGAGTTGGA GAAGATTGTC AAGCAAATCT CAGAAGATGC AAAGGCACCA 
CAAAAGAAGC ACAAGGTTCT TTTGCAACAG TTCAATACGG GCGATGAGAG AGCCCAGAAG 
CGCCAGCCTA TCCGCGGCTC TGATGAAGTT CTGTTTAAGG TCTATTGCAT GGACCACACC 
TACACAACCA TTCGGGTGCC AGTGGCCACT TCGGTGAAGG AAGTCATCAG TGCAGTTGCC 
GACAAGCTGG GCTCCGGGGA GGGCCTGATC ATAGTCAAGA TGAGTTCCGG AGGAGAAAAG 
GTGGTGCTCA AACCTAATGA TGTTTCAGTA TTTACGACGC TCACCATTAA TGGACGCCTG 
TTTGCTTGCC CGCGAGAGCA ATTCGATTCA CTGACTCCCT TACCAGAACA GGAAGGCCCA 
ACTGTTGGAA CAGTGGGAAC TTTTGAACTG ATGAGCTCCA AAGATTTAGC ATACCAGATG 
ACAATTTATG ATTGGGAACT CTTCAACTGC GTGCATGAGC TGGAGCTAAT CTATCACACA 
TTTGGAAGGC ATAATTTTAA AAAGACCACA GCAAACTTGG ATTTGTTCCT GAGGAGATTT 
AATGAAATTC AGTTTTGGGT CGTCACTGAG ATCTGCCTTT GTTCTCAGCT CAGCAAGCGT 
GTTCAGCTAT TAAAAAAATT TATTAAGATA GCAGCCCACT GTAAGGAGTA TAAAAATCTG 
AATTCCTTTT TTGCCATCGT CATGGGACTA AGTAACGTTG CTGTGAGCCG CTTGGCACTA 
ACGTGGGAGA AACTGCCAAG CAAGTTCAAG AAGTTCTATG CGGAGTTTGA AAGTTTAATG 
GACCCTTCAA GGAACCACAG GGCCTACAGG CTGACAGTAG CTAAGCTGGA ACCTCCTCTC 
ATCCCCTTCA TGCCTTTGCT CATTAAAGAT ATGACATTTA CTCATGAGGG GAACAAGACG 
TTCATTGACA ATCTAGTAAA CTTTGAAAAA ATGCGCATGA TTGCAAATAC GGCCAGAACA 
GTGAGATACT ACAGGAGCCA ACCCTTCAAT CCTGATGCAG CTCAAGCTAA TAAGAACCAT 
CAGGATGTCC GGAGTTATGT ACGGCAATTA AATGTGATTG ACAACCAGAG AACTTTATCA 
CAGATGTCAC ACAGATTAGA GCCTCGTCGA CCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Epac2-Rap1 Signaling Regulates Reactive Oxygen Species Production and Susceptibility to Cardiac Arrhythmias.
Antioxidants & redox signaling27(3)117-132(2017 Jul)
Yang Z,Kirton HM,Al-Owais M,Thireau J,Richard S,Peers C,Steele DS

The role of Epac in the heart.
Cellular and molecular life sciences : CMLS74(4)591-606(2017 Feb)
Fujita T,Umemura M,Yokoyama U,Okumura S,Ishikawa Y

Anxiety and depression with neurogenesis defects in exchange protein directly activated by cAMP 2-deficient mice are ameliorated by a selective serotonin reuptake inhibitor, Prozac.
Translational psychiatry6(9)e881(2016 09)
Zhou L,Ma SL,Yeung PK,Wong YH,Tsim KW,So KF,Lam LC,Chung SK

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RAPGEF4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

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