POP1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	POP1
Entrez Gene ID	10940
Full Name	POP1 homolog, ribonuclease P/MRP subunit
Synonyms	ANXD2
General protein information	Preferred Names POP1 homolog, ribonuclease P/MRP subunit Names ribonucleases P/MRP protein subunit POP1 hPOP1 processing of precursor 1, ribonuclease P/MRP subunit processing of precursors 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8q22.2
Summary	This gene encodes the protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing. This protein is also an autoantigen in patients suffering from connective tissue diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009].
Disorder MIM:	602486
Disorder Html:	Anauxetic dysplasia 2, 617396 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_011516801.2	XP_011515103.1	ribonucleases P/MRP protein subunit POP1 isoform X1
NM_001145860.1	NP_001139332.1	ribonucleases P/MRP protein subunit POP1
NM_001145861.2	NP_001139333.1	ribonucleases P/MRP protein subunit POP1
NM_015029.2	NP_055844.2	ribonucleases P/MRP protein subunit POP1
NM_001145861.1	NP_001139333.1	ribonucleases P/MRP protein subunit POP1
NM_001145860.2	NP_001139332.1	ribonucleases P/MRP protein subunit POP1

Pathways from BioSystems

Homologies

Homo sapiens (human)	POP1	NP_001139333.1
Drosophila melanogaster (fruit fly)	l(1)G0045	NP_572236.3
Xenopus tropicalis (tropical clawed frog)	pop1	XP_004915182.1
Mus musculus (house mouse)	Pop1	NP_690854.1
Danio rerio (zebrafish)	LOC799016	XP_001339421.5
Pan troglodytes (chimpanzee)	POP1	XP_001149384.1
	POP1	XP_002805472.1
Rattus norvegicus (Norway rat)	Pop1	NP_001124022.1
Gallus gallus (chicken)	POP1	XP_003640861.1
Bos taurus (cattle)	POP1	NP_001180144.1
Canis lupus familiaris (dog)	POP1	XP_005627870.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012125	XP_001689259.1

Gene Ontology
Bibliography

Related articles in PubMed

Broadening the phenotypic spectrum of POP1-skeletal dysplasias: identification of POP1 mutations in a mild and severe skeletal dysplasia.
Barraza-Garc?a J, Rivera-Pedroza CI, Hisado-Oliva A, Belinch?n-Mart?nez A, Sentchordi-Montan? L, Duncan EL, Clark GR, Del Pozo A, Ib??ez-Garikano K, Offiah A, Prieto-Matos P, Cormier-Daire V, Heath KE
Clinical genetics92(1)91-98(2017 Jul)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Further evidence of POP1 mutations as the cause of anauxetic dysplasia.
Elalaoui SC, Laarabi FZ, Mansouri M, Mrani NA, Nishimura G, Sefiani A
American journal of medical genetics. Part A170(9)2462-5(2016 Sep)

The PYRIN Domain-only Protein POP1 Inhibits Inflammasome Assembly and Ameliorates Inflammatory Disease.
de Almeida L, Khare S, Misharin AV, Patel R, Ratsimandresy RA, Wallin MC, Perlman H, Greaves DR, Hoffman HM, Dorfleutner A, Stehlik C
Immunity43(2)264-76(2015 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

we reported the third case with POP1-related AAD. This phenotype may appropriately be termed AAD type 2.
Title: Further evidence of POP1 mutations as the cause of anauxetic dysplasia.

by inhibiting inflammasome assembly, provides a regulatory feedback loop that shuts down excessive inflammatory responses; Cryopyrin-Associated Periodic Syndrome patients exhibit reduced expression
Title: The PYRIN Domain-only Protein POP1 Inhibits Inflammasome Assembly and Ameliorates Inflammatory Disease.

S-palmitoylation alters conformation or secondary structure of Trx1, as well as decreases the ability of Trx1 to transfer electrons from thioredoxin reductase to S-nitrosylated protein-tyrosine phosphatase 1B and S-nitroso-glutathione
Title: Crystal structure of human POP1 and its distinct structural feature for PYD domain.

Mitochondrial ribonuclease P structure provides insight into the evolution of catalytic strategies for precursor-trna 5' processing.
Title: Mitochondrial ribonuclease P structure provides insight into the evolution of catalytic strategies for precursor-tRNA 5' processing.

POP1 gene expression is increased in classic variant of papillary thyroid carcinoma.
Title: Differential expression of a set of genes in follicular and classic variants of papillary thyroid carcinoma.

The following POP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the POP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu64532	XM_011516801.2 Latest version!	Homo sapiens POP1 homolog, ribonuclease P/MRP subunit (POP1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu07644	NM_001145861.2 Latest version!	Homo sapiens POP1 homolog, ribonuclease P/MRP subunit (POP1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$69.30 $99.00
OHu07644	NM_001145860.2 Latest version!	Homo sapiens POP1 homolog, ribonuclease P/MRP subunit (POP1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$69.30 $99.00
OHu07644	NM_015029.2 Latest version!	Homo sapiens POP1 homolog, ribonuclease P/MRP subunit (POP1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$69.30 $99.00
View Old Accession Versions >>
OHu07644	NM_001145861.1	Homo sapiens POP1 homolog, ribonuclease P/MRP subunit (POP1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$69.30 $99.00
OHu07644	NM_001145860.1	Homo sapiens POP1 homolog, ribonuclease P/MRP subunit (POP1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$69.30 $99.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

POP1 ( XM_011516801.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011515103.1 Homo sapiens POP1 homolog, ribonuclease P/MRP subunit (POP1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu64532
Clone ID Related Accession (Same CDS sequence)	XM_011516801.2
Accession Version	XM_011516801.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1602bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ribonucleases P/MRP protein subunit POP1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011516801.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAAATG CAAAAGAAAG AAAACACGCC AAGAAAATGA GAAACCAGCC TACCAATGTG 
ACTCTGTCCT CTGGCTTTGT GGCTGACAGA GGTGTAAAGC ACCACAGTGG AGGTGAAAAA 
CCTTTCCAAG CTCAAAAACA AGAGCCTCAT CCTGGAACTT CACGACAGCG GCAAACCAGA 
GTCAACCCCC ATTCTCTGCC TGACCCTGAA GTGAATGAGC AGTCTTCCTC CAAAGGGATG 
TTTAGAAAAA AGGGAGGATG GAAAGCAGGT CCCGAGGGCA CGTCTCAGGA GATCCCCAAG 
TATATAACTG CTTCTACTTT TGCTCAAGCA CGAGCTGCTG AAATCAGTGC TATGTTAAAA 
GCTGTGACCC AGAAGTCTTC GAATTCACTG GTTTTTCAGA CTCTGCCACG GCACATGCGA 
CGAAGAGCCA TGAGCCACAA CGTCAAACGC CTTCCCAGAC GGTTACAGGA GATTGCCCAG 
AAAGAGGCGG AGAAAGCCGT ACATCAGAAA AAAGAACATT CAAAAAATAA ATGCCATAAA 
GCTCGAAGAT GTCACATGAA CCGGACGCTA GAATTTAACC GTAGACAAAA GAAGAACATT 
TGGTTAGAAA CTCACATCTG GCACGCCAAG CGGTTTCATA TGGTCAAGAA GTGGGGCTAC 
TGCCTTGGGG AGAGGCCAAC AGTCAAGAGC CACAGAGCCT GCTATCGAGC CATGACGAAC 
CGGTGCCTCC TGCAGGATTT ATCCTATTAC TGTTGTTTGG AGTTGAAAGG CAAAGAGGAA 
GAAATACTAA AGGCGCTTTC TGGAATGTGT AACATAGACA CAGGGCTGAC GTTTGCAGCA 
GTTCACTGCT TGTCTGGAAA GCGCCAAGGG AGCCTTGTGC TTTATCGGGT GAATAAATAT 
CCCAGAGAAA TGCTTGGGCC TGTTACGTTT ATCTGGAAGT CCCAGAGGAC CCCGGGTGAC 
CCTTCTGAGA GCAGGCAGCT GTGGATCTGG CTGCATCCAA CCCTTAAACA GGATATCTTA 
GAGGAAATAA AAGCAGCGTG CCAGTGTGTG GAACCCATCA AATCAGCTGT CTGCATCGCT 
GACCCACTTC CAACACCATC CCAAGAAAAA AGCCAAACTG AATTGCCTGA CGAGAAAATT 
GGCAAGAAAA GAAAAAGGAA AGATGATGGA GAAAATGCTA AACCAATTAA AAAAATTATC 
GGTGATGGAA CTAGAGATCC ATGTCTACCA TACTCTTGGA TCTCTCCAAC CACAGGCATT 
ATAATCAGCG ATTTGACGAT GGAGATGAAC AGATTCCGGC TGATTGGGCC ACTTTCCCAC 
TCCATCCTAA CTGAAGCAAT AAAAGCTGCT TCTGTCCACA CTGTGGGAGA GGACACAGAG 
GAGACACCTC ACCGCTGGTG GATAGAAACC TGTAAGAAAC CTGACAGCGT TTCCCTTCAT 
TGCAGACAAG AAGCCATTTT CGAGTTGTTG GGAGGAATAA CATCACCAGC AGAAATTCCG 
GCAGGTACTA TTCTGGGACT GACAGTTGGG GATCCTCGAA TAAATTTGCC CCAAAAGAAG 
TCCAAAGCTT TGCCCAATCC AGAAAAATGC CAAGAATTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011515103.1
CDS	101..1702
Translation	MSNAKERKHAKKMRNQPTNVTLSSGFVADRGVKHHSGGEKPFQAQKQEPHPGTSRQRQTRVNPHSLPDPEVNEQSSSKGMFRKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQKSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEIAQKEAEKAVHQKKEHSKNKCHKARRCHMNRTLEFNRRQKKNIWLETHIWHAKRFHMVKKWGYCLGERPTVKSHRACYRAMTNRCLLQDLSYYCCLELKGKEEEILKALSGMCNIDTGLTFAAVHCLSGKRQGSLVLYRVNKYPREMLGPVTFIWKSQRTPGDPSESRQLWIWLHPTLKQDILEEIKAACQCVEPIKSAVCIADPLPTPSQEKSQTELPDEKIGKKRKRKDDGENAKPIKKIIGDGTRDPCLPYSWISPTTGIIISDLTMEMNRFRLIGPLSHSILTEAIKAASVHTVGEDTEETPHRWWIETCKKPDSVSLHCRQEAIFELLGGITSPAEIPAGTILGLTVGDPRINLPQKKSKALPNPEKCQEF

Target ORF information:

RefSeq Version	XM_011516801.2
Organism	Homo sapiens(human)
Definition	Homo sapiens POP1 homolog, ribonuclease P/MRP subunit (POP1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011516801.2

ORF Insert Sequence:

ATGTCAAATG CAAAAGAAAG AAAACACGCC AAGAAAATGA GAAACCAGCC TACCAATGTG 
ACTCTGTCCT CTGGCTTTGT GGCTGACAGA GGTGTAAAGC ACCACAGTGG AGGTGAAAAA 
CCTTTCCAAG CTCAAAAACA AGAGCCTCAT CCTGGAACTT CACGACAGCG GCAAACCAGA 
GTCAACCCCC ATTCTCTGCC TGACCCTGAA GTGAATGAGC AGTCTTCCTC CAAAGGGATG 
TTTAGAAAAA AGGGAGGATG GAAAGCAGGT CCCGAGGGCA CGTCTCAGGA GATCCCCAAG 
TATATAACTG CTTCTACTTT TGCTCAAGCA CGAGCTGCTG AAATCAGTGC TATGTTAAAA 
GCTGTGACCC AGAAGTCTTC GAATTCACTG GTTTTTCAGA CTCTGCCACG GCACATGCGA 
CGAAGAGCCA TGAGCCACAA CGTCAAACGC CTTCCCAGAC GGTTACAGGA GATTGCCCAG 
AAAGAGGCGG AGAAAGCCGT ACATCAGAAA AAAGAACATT CAAAAAATAA ATGCCATAAA 
GCTCGAAGAT GTCACATGAA CCGGACGCTA GAATTTAACC GTAGACAAAA GAAGAACATT 
TGGTTAGAAA CTCACATCTG GCACGCCAAG CGGTTTCATA TGGTCAAGAA GTGGGGCTAC 
TGCCTTGGGG AGAGGCCAAC AGTCAAGAGC CACAGAGCCT GCTATCGAGC CATGACGAAC 
CGGTGCCTCC TGCAGGATTT ATCCTATTAC TGTTGTTTGG AGTTGAAAGG CAAAGAGGAA 
GAAATACTAA AGGCGCTTTC TGGAATGTGT AACATAGACA CAGGGCTGAC GTTTGCAGCA 
GTTCACTGCT TGTCTGGAAA GCGCCAAGGG AGCCTTGTGC TTTATCGGGT GAATAAATAT 
CCCAGAGAAA TGCTTGGGCC TGTTACGTTT ATCTGGAAGT CCCAGAGGAC CCCGGGTGAC 
CCTTCTGAGA GCAGGCAGCT GTGGATCTGG CTGCATCCAA CCCTTAAACA GGATATCTTA 
GAGGAAATAA AAGCAGCGTG CCAGTGTGTG GAACCCATCA AATCAGCTGT CTGCATCGCT 
GACCCACTTC CAACACCATC CCAAGAAAAA AGCCAAACTG AATTGCCTGA CGAGAAAATT 
GGCAAGAAAA GAAAAAGGAA AGATGATGGA GAAAATGCTA AACCAATTAA AAAAATTATC 
GGTGATGGAA CTAGAGATCC ATGTCTACCA TACTCTTGGA TCTCTCCAAC CACAGGCATT 
ATAATCAGCG ATTTGACGAT GGAGATGAAC AGATTCCGGC TGATTGGGCC ACTTTCCCAC 
TCCATCCTAA CTGAAGCAAT AAAAGCTGCT TCTGTCCACA CTGTGGGAGA GGACACAGAG 
GAGACACCTC ACCGCTGGTG GATAGAAACC TGTAAGAAAC CTGACAGCGT TTCCCTTCAT 
TGCAGACAAG AAGCCATTTT CGAGTTGTTG GGAGGAATAA CATCACCAGC AGAAATTCCG 
GCAGGTACTA TTCTGGGACT GACAGTTGGG GATCCTCGAA TAAATTTGCC CCAAAAGAAG 
TCCAAAGCTT TGCCCAATCC AGAAAAATGC CAAGAATTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

POP1 ( NM_001145860.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001139332.1 Homo sapiens POP1 homolog, ribonuclease P/MRP subunit (POP1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu07644
Clone ID Related Accession (Same CDS sequence)	NM_001145860.1 , NM_001145861.2 , NM_015029.2 , NM_001145861.1 , NM_001145860.2
Accession Version	NM_001145860.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3075bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-22
Organism	Homo sapiens(human)
Product	ribonucleases P/MRP protein subunit POP1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from X99302.1, AK291434.1, D31765.1, AP003439.2 and BF511088.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.265777.1, SRR1803616.101407.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGTCAAATG CAAAAGAAAG AAAACACGCC AAGAAAATGA GAAACCAGCC TACCAATGTG 
ACTCTGTCCT CTGGCTTTGT GGCTGACAGA GGTGTAAAGC ACCACAGTGG AGGTGAAAAA 
CCTTTCCAAG CTCAAAAACA AGAGCCTCAT CCTGGAACTT CACGACAGCG GCAAACCAGA 
GTCAACCCCC ATTCTCTGCC TGACCCTGAA GTGAATGAGC AGTCTTCCTC CAAAGGGATG 
TTTAGAAAAA AGGGAGGATG GAAAGCAGGT CCCGAGGGCA CGTCTCAGGA GATCCCCAAG 
TATATAACTG CTTCTACTTT TGCTCAAGCA CGAGCTGCTG AAATCAGTGC TATGTTAAAA 
GCTGTGACCC AGAAGTCTTC GAATTCACTG GTTTTTCAGA CTCTGCCACG GCACATGCGA 
CGAAGAGCCA TGAGCCACAA CGTCAAACGC CTTCCCAGAC GGTTACAGGA GATTGCCCAG 
AAAGAGGCGG AGAAAGCCGT ACATCAGAAA AAAGAACATT CAAAAAATAA ATGCCATAAA 
GCTCGAAGAT GTCACATGAA CCGGACGCTA GAATTTAACC GTAGACAAAA GAAGAACATT 
TGGTTAGAAA CTCACATCTG GCACGCCAAG CGGTTTCATA TGGTCAAGAA GTGGGGCTAC 
TGCCTTGGGG AGAGGCCAAC AGTCAAGAGC CACAGAGCCT GCTATCGAGC CATGACGAAC 
CGGTGCCTCC TGCAGGATTT ATCCTATTAC TGTTGTTTGG AGTTGAAAGG CAAAGAGGAA 
GAAATACTAA AGGCGCTTTC TGGAATGTGT AACATAGACA CAGGGCTGAC GTTTGCAGCA 
GTTCACTGCT TGTCTGGAAA GCGCCAAGGG AGCCTTGTGC TTTATCGGGT GAATAAATAT 
CCCAGAGAAA TGCTTGGGCC TGTTACGTTT ATCTGGAAGT CCCAGAGGAC CCCGGGTGAC 
CCTTCTGAGA GCAGGCAGCT GTGGATCTGG CTGCATCCAA CCCTTAAACA GGATATCTTA 
GAGGAAATAA AAGCAGCGTG CCAGTGTGTG GAACCCATCA AATCAGCTGT CTGCATCGCT 
GACCCACTTC CAACACCATC CCAAGAAAAA AGCCAAACTG AATTGCCTGA CGAGAAAATT 
GGCAAGAAAA GAAAAAGGAA AGATGATGGA GAAAATGCTA AACCAATTAA AAAAATTATC 
GGTGATGGAA CTAGAGATCC ATGTCTACCA TACTCTTGGA TCTCTCCAAC CACAGGCATT 
ATAATCAGCG ATTTGACGAT GGAGATGAAC AGATTCCGGC TGATTGGGCC ACTTTCCCAC 
TCCATCCTAA CTGAAGCAAT AAAAGCTGCT TCTGTCCACA CTGTGGGAGA GGACACAGAG 
GAGACACCTC ACCGCTGGTG GATAGAAACC TGTAAGAAAC CTGACAGCGT TTCCCTTCAT 
TGCAGACAAG AAGCCATTTT CGAGTTGTTG GGAGGAATAA CATCACCAGC AGAAATTCCG 
GCAGGTACTA TTCTGGGACT GACAGTTGGG GATCCTCGAA TAAATTTGCC CCAAAAGAAG 
TCCAAAGCTT TGCCCAATCC AGAAAAATGC CAAGATAATG AGAAAGTTAG ACAGCTGCTT 
CTGGAGGGTG TGCCTGTGGA ATGTACGCAT AGCTTTATCT GGAACCAAGA TATCTGTAAG 
AGTGTCACAG AGAATAAAAT CTCGGATCAG GATTTAAACC GGATGAGGAG TGAATTGCTG 
GTGCCTGGGT CACAGCTTAT TTTAGGTCCC CATGAATCCA AGATACCTAT ACTTTTGATT 
CAGCAGCCAG GAAAAGTGAC TGGTGAAGAT CGACTAGGCT GGGGAAGTGG CTGGGATGTC 
CTACTCCCAA AGGGCTGGGG CATGGCTTTC TGGATTCCAT TTATTTATCG AGGTGTGAGA 
GTCGGAGGGT TGAAAGAGTC TGCAGTGCAT TCTCAGTATA AGAGGTCGCC TAATGTCCCA 
GGCGATTTTC CAGACTGCCC TGCCGGGATG CTGTTTGCGG AAGAGCAAGC TAAGAATCTT 
CTTGAAAAGT ACAAAAGACG CCCTCCTGCA AAACGGCCCA ACTACGTTAA GCTTGGCACT 
CTGGCACCTT TCTGCTGTCC CTGGGAGCAG TTAACTCAAG ACTGGGAGTC AAGAGTCCAG 
GCTTACGAAG AACCTTCTGT AGCTTCATCT CCAAATGGTA AGGAGAGTGA CCTAAGAAGA 
TCTGAGGTGC CTTGTGCTCC CATGCCTAAA AAAACTCATC AGCCATCTGA TGAAGTGGGC 
ACATCCATAG AGCACCCCAG GGAGGCAGAG GAGGTAATGG ATGCAGGGTG TCAAGAATCG 
GCAGGGCCTG AGAGGATCAC AGACCAGGAG GCCAGTGAAA ACCATGTTGC TGCCACAGGG 
AGTCACCTCT GCGTTCTCAG GAGTAGAAAA TTACTGAAGC AACTGTCAGC CTGGTGTGGG 
CCCAGTTCTG AGGATAGTCG GGGAGGCCGG CGAGCTCCCG GCAGAGGCCA GCAAGGATTG 
ACCAGAGAGG CTTGCCTGTC CATCTTGGGC CACTTCCCCA GGGCCCTGGT TTGGGTCAGC 
CTGTCCCTGC TCAGCAAGGG CAGCCCCGAG CCTCACACCA TGATCTGTGT CCCAGCCAAG 
GAGGACTTCC TCCAGCTCCA TGAGGACTGG CATTACTGTG GGCCCCAGGA ATCCAAACAC 
AGTGACCCAT TCAGGAGCAA GATCCTGAAA CAGAAAGAGA AGAAGAAAAG GGAGAAGAGG 
CAGAAGCCAG GACGTGCCTC TTCTGATGGC CCGGCGGGGG AAGAGCCCGT GGCTGGGCAG 
GAAGCTCTGA CTCTAGGGCT GTGGTCAGGC CCTCTGCCGC GTGTGACGTT GCACTGCTCC 
AGAACTCTCC TAGGCTTTGT GACTCAGGGA GATTTTTCCA TGGCTGTTGG CTGTGGAGAA 
GCCCTGGGGT TTGTTAGCTT GACAGGCTTG CTGGATATGC TGTCCAGCCA GCCTGCAGCG 
CAGAGGGGCT TAGTGCTACT GAGGCCTCCC GCCTCTCTGC AGTATCGATT TGCGAGGATT 
GCTATTGAGG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001139332.1
CDS	101..3175
Translation	MSNAKERKHAKKMRNQPTNVTLSSGFVADRGVKHHSGGEKPFQAQKQEPHPGTSRQRQTRVNPHSLPDPEVNEQSSSKGMFRKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQKSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEIAQKEAEKAVHQKKEHSKNKCHKARRCHMNRTLEFNRRQKKNIWLETHIWHAKRFHMVKKWGYCLGERPTVKSHRACYRAMTNRCLLQDLSYYCCLELKGKEEEILKALSGMCNIDTGLTFAAVHCLSGKRQGSLVLYRVNKYPREMLGPVTFIWKSQRTPGDPSESRQLWIWLHPTLKQDILEEIKAACQCVEPIKSAVCIADPLPTPSQEKSQTELPDEKIGKKRKRKDDGENAKPIKKIIGDGTRDPCLPYSWISPTTGIIISDLTMEMNRFRLIGPLSHSILTEAIKAASVHTVGEDTEETPHRWWIETCKKPDSVSLHCRQEAIFELLGGITSPAEIPAGTILGLTVGDPRINLPQKKSKALPNPEKCQDNEKVRQLLLEGVPVECTHSFIWNQDICKSVTENKISDQDLNRMRSELLVPGSQLILGPHESKIPILLIQQPGKVTGEDRLGWGSGWDVLLPKGWGMAFWIPFIYRGVRVGGLKESAVHSQYKRSPNVPGDFPDCPAGMLFAEEQAKNLLEKYKRRPPAKRPNYVKLGTLAPFCCPWEQLTQDWESRVQAYEEPSVASSPNGKESDLRRSEVPCAPMPKKTHQPSDEVGTSIEHPREAEEVMDAGCQESAGPERITDQEASENHVAATGSHLCVLRSRKLLKQLSAWCGPSSEDSRGGRRAPGRGQQGLTREACLSILGHFPRALVWVSLSLLSKGSPEPHTMICVPAKEDFLQLHEDWHYCGPQESKHSDPFRSKILKQKEKKKREKRQKPGRASSDGPAGEEPVAGQEALTLGLWSGPLPRVTLHCSRTLLGFVTQGDFSMAVGCGEALGFVSLTGLLDMLSSQPAAQRGLVLLRPPASLQYRFARIAIEV

Target ORF information:

RefSeq Version	NM_001145860.1
Organism	Homo sapiens(human)
Definition	Homo sapiens POP1 homolog, ribonuclease P/MRP subunit (POP1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145860.1

ORF Insert Sequence:

ATGTCAAATG CAAAAGAAAG AAAACACGCC AAGAAAATGA GAAACCAGCC TACCAATGTG 
ACTCTGTCCT CTGGCTTTGT GGCTGACAGA GGTGTAAAGC ACCACAGTGG AGGTGAAAAA 
CCTTTCCAAG CTCAAAAACA AGAGCCTCAT CCTGGAACTT CACGACAGCG GCAAACCAGA 
GTCAACCCCC ATTCTCTGCC TGACCCTGAA GTGAATGAGC AGTCTTCCTC CAAAGGGATG 
TTTAGAAAAA AGGGAGGATG GAAAGCAGGT CCCGAGGGCA CGTCTCAGGA GATCCCCAAG 
TATATAACTG CTTCTACTTT TGCTCAAGCA CGAGCTGCTG AAATCAGTGC TATGTTAAAA 
GCTGTGACCC AGAAGTCTTC GAATTCACTG GTTTTTCAGA CTCTGCCACG GCACATGCGA 
CGAAGAGCCA TGAGCCACAA CGTCAAACGC CTTCCCAGAC GGTTACAGGA GATTGCCCAG 
AAAGAGGCGG AGAAAGCCGT ACATCAGAAA AAAGAACATT CAAAAAATAA ATGCCATAAA 
GCTCGAAGAT GTCACATGAA CCGGACGCTA GAATTTAACC GTAGACAAAA GAAGAACATT 
TGGTTAGAAA CTCACATCTG GCACGCCAAG CGGTTTCATA TGGTCAAGAA GTGGGGCTAC 
TGCCTTGGGG AGAGGCCAAC AGTCAAGAGC CACAGAGCCT GCTATCGAGC CATGACGAAC 
CGGTGCCTCC TGCAGGATTT ATCCTATTAC TGTTGTTTGG AGTTGAAAGG CAAAGAGGAA 
GAAATACTAA AGGCGCTTTC TGGAATGTGT AACATAGACA CAGGGCTGAC GTTTGCAGCA 
GTTCACTGCT TGTCTGGAAA GCGCCAAGGG AGCCTTGTGC TTTATCGGGT GAATAAATAT 
CCCAGAGAAA TGCTTGGGCC TGTTACGTTT ATCTGGAAGT CCCAGAGGAC CCCGGGTGAC 
CCTTCTGAGA GCAGGCAGCT GTGGATCTGG CTGCATCCAA CCCTTAAACA GGATATCTTA 
GAGGAAATAA AAGCAGCGTG CCAGTGTGTG GAACCCATCA AATCAGCTGT CTGCATCGCT 
GACCCACTTC CAACACCATC CCAAGAAAAA AGCCAAACTG AATTGCCTGA CGAGAAAATT 
GGCAAGAAAA GAAAAAGGAA AGATGATGGA GAAAATGCTA AACCAATTAA AAAAATTATC 
GGTGATGGAA CTAGAGATCC ATGTCTACCA TACTCTTGGA TCTCTCCAAC CACAGGCATT 
ATAATCAGCG ATTTGACGAT GGAGATGAAC AGATTCCGGC TGATTGGGCC ACTTTCCCAC 
TCCATCCTAA CTGAAGCAAT AAAAGCTGCT TCTGTCCACA CTGTGGGAGA GGACACAGAG 
GAGACACCTC ACCGCTGGTG GATAGAAACC TGTAAGAAAC CTGACAGCGT TTCCCTTCAT 
TGCAGACAAG AAGCCATTTT CGAGTTGTTG GGAGGAATAA CATCACCAGC AGAAATTCCG 
GCAGGTACTA TTCTGGGACT GACAGTTGGG GATCCTCGAA TAAATTTGCC CCAAAAGAAG 
TCCAAAGCTT TGCCCAATCC AGAAAAATGC CAAGATAATG AGAAAGTTAG ACAGCTGCTT 
CTGGAGGGTG TGCCTGTGGA ATGTACGCAT AGCTTTATCT GGAACCAAGA TATCTGTAAG 
AGTGTCACAG AGAATAAAAT CTCGGATCAG GATTTAAACC GGATGAGGAG TGAATTGCTG 
GTGCCTGGGT CACAGCTTAT TTTAGGTCCC CATGAATCCA AGATACCTAT ACTTTTGATT 
CAGCAGCCAG GAAAAGTGAC TGGTGAAGAT CGACTAGGCT GGGGAAGTGG CTGGGATGTC 
CTACTCCCAA AGGGCTGGGG CATGGCTTTC TGGATTCCAT TTATTTATCG AGGTGTGAGA 
GTCGGAGGGT TGAAAGAGTC TGCAGTGCAT TCTCAGTATA AGAGGTCGCC TAATGTCCCA 
GGCGATTTTC CAGACTGCCC TGCCGGGATG CTGTTTGCGG AAGAGCAAGC TAAGAATCTT 
CTTGAAAAGT ACAAAAGACG CCCTCCTGCA AAACGGCCCA ACTACGTTAA GCTTGGCACT 
CTGGCACCTT TCTGCTGTCC CTGGGAGCAG TTAACTCAAG ACTGGGAGTC AAGAGTCCAG 
GCTTACGAAG AACCTTCTGT AGCTTCATCT CCAAATGGTA AGGAGAGTGA CCTAAGAAGA 
TCTGAGGTGC CTTGTGCTCC CATGCCTAAA AAAACTCATC AGCCATCTGA TGAAGTGGGC 
ACATCCATAG AGCACCCCAG GGAGGCAGAG GAGGTAATGG ATGCAGGGTG TCAAGAATCG 
GCAGGGCCTG AGAGGATCAC AGACCAGGAG GCCAGTGAAA ACCATGTTGC TGCCACAGGG 
AGTCACCTCT GCGTTCTCAG GAGTAGAAAA TTACTGAAGC AACTGTCAGC CTGGTGTGGG 
CCCAGTTCTG AGGATAGTCG GGGAGGCCGG CGAGCTCCCG GCAGAGGCCA GCAAGGATTG 
ACCAGAGAGG CTTGCCTGTC CATCTTGGGC CACTTCCCCA GGGCCCTGGT TTGGGTCAGC 
CTGTCCCTGC TCAGCAAGGG CAGCCCCGAG CCTCACACCA TGATCTGTGT CCCAGCCAAG 
GAGGACTTCC TCCAGCTCCA TGAGGACTGG CATTACTGTG GGCCCCAGGA ATCCAAACAC 
AGTGACCCAT TCAGGAGCAA GATCCTGAAA CAGAAAGAGA AGAAGAAAAG GGAGAAGAGG 
CAGAAGCCAG GACGTGCCTC TTCTGATGGC CCGGCGGGGG AAGAGCCCGT GGCTGGGCAG 
GAAGCTCTGA CTCTAGGGCT GTGGTCAGGC CCTCTGCCGC GTGTGACGTT GCACTGCTCC 
AGAACTCTCC TAGGCTTTGT GACTCAGGGA GATTTTTCCA TGGCTGTTGG CTGTGGAGAA 
GCCCTGGGGT TTGTTAGCTT GACAGGCTTG CTGGATATGC TGTCCAGCCA GCCTGCAGCG 
CAGAGGGGCT TAGTGCTACT GAGGCCTCCC GCCTCTCTGC AGTATCGATT TGCGAGGATT 
GCTATTGAGG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

POP1 ( NM_001145861.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001139333.1 Homo sapiens POP1 homolog, ribonuclease P/MRP subunit (POP1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu07644
Clone ID Related Accession (Same CDS sequence)	NM_001145860.1 , NM_001145861.2 , NM_015029.2 , NM_001145861.1 , NM_001145860.2
Accession Version	NM_001145861.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3075bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	ribonucleases P/MRP protein subunit POP1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP280616.1, BP249298.1, AK291434.1, D31765.1, AP003439.2 and BF511088.1. On May 31, 2019 this sequence version replaced NM_001145861.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGTCAAATG CAAAAGAAAG AAAACACGCC AAGAAAATGA GAAACCAGCC TACCAATGTG 
ACTCTGTCCT CTGGCTTTGT GGCTGACAGA GGTGTAAAGC ACCACAGTGG AGGTGAAAAA 
CCTTTCCAAG CTCAAAAACA AGAGCCTCAT CCTGGAACTT CACGACAGCG GCAAACCAGA 
GTCAACCCCC ATTCTCTGCC TGACCCTGAA GTGAATGAGC AGTCTTCCTC CAAAGGGATG 
TTTAGAAAAA AGGGAGGATG GAAAGCAGGT CCCGAGGGCA CGTCTCAGGA GATCCCCAAG 
TATATAACTG CTTCTACTTT TGCTCAAGCA CGAGCTGCTG AAATCAGTGC TATGTTAAAA 
GCTGTGACCC AGAAGTCTTC GAATTCACTG GTTTTTCAGA CTCTGCCACG GCACATGCGA 
CGAAGAGCCA TGAGCCACAA CGTCAAACGC CTTCCCAGAC GGTTACAGGA GATTGCCCAG 
AAAGAGGCGG AGAAAGCCGT ACATCAGAAA AAAGAACATT CAAAAAATAA ATGCCATAAA 
GCTCGAAGAT GTCACATGAA CCGGACGCTA GAATTTAACC GTAGACAAAA GAAGAACATT 
TGGTTAGAAA CTCACATCTG GCACGCCAAG CGGTTTCATA TGGTCAAGAA GTGGGGCTAC 
TGCCTTGGGG AGAGGCCAAC AGTCAAGAGC CACAGAGCCT GCTATCGAGC CATGACGAAC 
CGGTGCCTCC TGCAGGATTT ATCCTATTAC TGTTGTTTGG AGTTGAAAGG CAAAGAGGAA 
GAAATACTAA AGGCGCTTTC TGGAATGTGT AACATAGACA CAGGGCTGAC GTTTGCAGCA 
GTTCACTGCT TGTCTGGAAA GCGCCAAGGG AGCCTTGTGC TTTATCGGGT GAATAAATAT 
CCCAGAGAAA TGCTTGGGCC TGTTACGTTT ATCTGGAAGT CCCAGAGGAC CCCGGGTGAC 
CCTTCTGAGA GCAGGCAGCT GTGGATCTGG CTGCATCCAA CCCTTAAACA GGATATCTTA 
GAGGAAATAA AAGCAGCGTG CCAGTGTGTG GAACCCATCA AATCAGCTGT CTGCATCGCT 
GACCCACTTC CAACACCATC CCAAGAAAAA AGCCAAACTG AATTGCCTGA CGAGAAAATT 
GGCAAGAAAA GAAAAAGGAA AGATGATGGA GAAAATGCTA AACCAATTAA AAAAATTATC 
GGTGATGGAA CTAGAGATCC ATGTCTACCA TACTCTTGGA TCTCTCCAAC CACAGGCATT 
ATAATCAGCG ATTTGACGAT GGAGATGAAC AGATTCCGGC TGATTGGGCC ACTTTCCCAC 
TCCATCCTAA CTGAAGCAAT AAAAGCTGCT TCTGTCCACA CTGTGGGAGA GGACACAGAG 
GAGACACCTC ACCGCTGGTG GATAGAAACC TGTAAGAAAC CTGACAGCGT TTCCCTTCAT 
TGCAGACAAG AAGCCATTTT CGAGTTGTTG GGAGGAATAA CATCACCAGC AGAAATTCCG 
GCAGGTACTA TTCTGGGACT GACAGTTGGG GATCCTCGAA TAAATTTGCC CCAAAAGAAG 
TCCAAAGCTT TGCCCAATCC AGAAAAATGC CAAGATAATG AGAAAGTTAG ACAGCTGCTT 
CTGGAGGGTG TGCCTGTGGA ATGTACGCAT AGCTTTATCT GGAACCAAGA TATCTGTAAG 
AGTGTCACAG AGAATAAAAT CTCGGATCAG GATTTAAACC GGATGAGGAG TGAATTGCTG 
GTGCCTGGGT CACAGCTTAT TTTAGGTCCC CATGAATCCA AGATACCTAT ACTTTTGATT 
CAGCAGCCAG GAAAAGTGAC TGGTGAAGAT CGACTAGGCT GGGGAAGTGG CTGGGATGTC 
CTACTCCCAA AGGGCTGGGG CATGGCTTTC TGGATTCCAT TTATTTATCG AGGTGTGAGA 
GTCGGAGGGT TGAAAGAGTC TGCAGTGCAT TCTCAGTATA AGAGGTCGCC TAATGTCCCA 
GGCGATTTTC CAGACTGCCC TGCCGGGATG CTGTTTGCGG AAGAGCAAGC TAAGAATCTT 
CTTGAAAAGT ACAAAAGACG CCCTCCTGCA AAACGGCCCA ACTACGTTAA GCTTGGCACT 
CTGGCACCTT TCTGCTGTCC CTGGGAGCAG TTAACTCAAG ACTGGGAGTC AAGAGTCCAG 
GCTTACGAAG AACCTTCTGT AGCTTCATCT CCAAATGGTA AGGAGAGTGA CCTAAGAAGA 
TCTGAGGTGC CTTGTGCTCC CATGCCTAAA AAAACTCATC AGCCATCTGA TGAAGTGGGC 
ACATCCATAG AGCACCCCAG GGAGGCAGAG GAGGTAATGG ATGCAGGGTG TCAAGAATCG 
GCAGGGCCTG AGAGGATCAC AGACCAGGAG GCCAGTGAAA ACCATGTTGC TGCCACAGGG 
AGTCACCTCT GCGTTCTCAG GAGTAGAAAA TTACTGAAGC AACTGTCAGC CTGGTGTGGG 
CCCAGTTCTG AGGATAGTCG GGGAGGCCGG CGAGCTCCCG GCAGAGGCCA GCAAGGATTG 
ACCAGAGAGG CTTGCCTGTC CATCTTGGGC CACTTCCCCA GGGCCCTGGT TTGGGTCAGC 
CTGTCCCTGC TCAGCAAGGG CAGCCCCGAG CCTCACACCA TGATCTGTGT CCCAGCCAAG 
GAGGACTTCC TCCAGCTCCA TGAGGACTGG CATTACTGTG GGCCCCAGGA ATCCAAACAC 
AGTGACCCAT TCAGGAGCAA GATCCTGAAA CAGAAAGAGA AGAAGAAAAG GGAGAAGAGG 
CAGAAGCCAG GACGTGCCTC TTCTGATGGC CCGGCGGGGG AAGAGCCCGT GGCTGGGCAG 
GAAGCTCTGA CTCTAGGGCT GTGGTCAGGC CCTCTGCCGC GTGTGACGTT GCACTGCTCC 
AGAACTCTCC TAGGCTTTGT GACTCAGGGA GATTTTTCCA TGGCTGTTGG CTGTGGAGAA 
GCCCTGGGGT TTGTTAGCTT GACAGGCTTG CTGGATATGC TGTCCAGCCA GCCTGCAGCG 
CAGAGGGGCT TAGTGCTACT GAGGCCTCCC GCCTCTCTGC AGTATCGATT TGCGAGGATT 
GCTATTGAGG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001139333.1
CDS	41..3115
Translation	MSNAKERKHAKKMRNQPTNVTLSSGFVADRGVKHHSGGEKPFQAQKQEPHPGTSRQRQTRVNPHSLPDPEVNEQSSSKGMFRKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQKSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEIAQKEAEKAVHQKKEHSKNKCHKARRCHMNRTLEFNRRQKKNIWLETHIWHAKRFHMVKKWGYCLGERPTVKSHRACYRAMTNRCLLQDLSYYCCLELKGKEEEILKALSGMCNIDTGLTFAAVHCLSGKRQGSLVLYRVNKYPREMLGPVTFIWKSQRTPGDPSESRQLWIWLHPTLKQDILEEIKAACQCVEPIKSAVCIADPLPTPSQEKSQTELPDEKIGKKRKRKDDGENAKPIKKIIGDGTRDPCLPYSWISPTTGIIISDLTMEMNRFRLIGPLSHSILTEAIKAASVHTVGEDTEETPHRWWIETCKKPDSVSLHCRQEAIFELLGGITSPAEIPAGTILGLTVGDPRINLPQKKSKALPNPEKCQDNEKVRQLLLEGVPVECTHSFIWNQDICKSVTENKISDQDLNRMRSELLVPGSQLILGPHESKIPILLIQQPGKVTGEDRLGWGSGWDVLLPKGWGMAFWIPFIYRGVRVGGLKESAVHSQYKRSPNVPGDFPDCPAGMLFAEEQAKNLLEKYKRRPPAKRPNYVKLGTLAPFCCPWEQLTQDWESRVQAYEEPSVASSPNGKESDLRRSEVPCAPMPKKTHQPSDEVGTSIEHPREAEEVMDAGCQESAGPERITDQEASENHVAATGSHLCVLRSRKLLKQLSAWCGPSSEDSRGGRRAPGRGQQGLTREACLSILGHFPRALVWVSLSLLSKGSPEPHTMICVPAKEDFLQLHEDWHYCGPQESKHSDPFRSKILKQKEKKKREKRQKPGRASSDGPAGEEPVAGQEALTLGLWSGPLPRVTLHCSRTLLGFVTQGDFSMAVGCGEALGFVSLTGLLDMLSSQPAAQRGLVLLRPPASLQYRFARIAIEV

Target ORF information:

RefSeq Version	NM_001145861.2
Organism	Homo sapiens(human)
Definition	Homo sapiens POP1 homolog, ribonuclease P/MRP subunit (POP1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145861.2

ORF Insert Sequence:

ATGTCAAATG CAAAAGAAAG AAAACACGCC AAGAAAATGA GAAACCAGCC TACCAATGTG 
ACTCTGTCCT CTGGCTTTGT GGCTGACAGA GGTGTAAAGC ACCACAGTGG AGGTGAAAAA 
CCTTTCCAAG CTCAAAAACA AGAGCCTCAT CCTGGAACTT CACGACAGCG GCAAACCAGA 
GTCAACCCCC ATTCTCTGCC TGACCCTGAA GTGAATGAGC AGTCTTCCTC CAAAGGGATG 
TTTAGAAAAA AGGGAGGATG GAAAGCAGGT CCCGAGGGCA CGTCTCAGGA GATCCCCAAG 
TATATAACTG CTTCTACTTT TGCTCAAGCA CGAGCTGCTG AAATCAGTGC TATGTTAAAA 
GCTGTGACCC AGAAGTCTTC GAATTCACTG GTTTTTCAGA CTCTGCCACG GCACATGCGA 
CGAAGAGCCA TGAGCCACAA CGTCAAACGC CTTCCCAGAC GGTTACAGGA GATTGCCCAG 
AAAGAGGCGG AGAAAGCCGT ACATCAGAAA AAAGAACATT CAAAAAATAA ATGCCATAAA 
GCTCGAAGAT GTCACATGAA CCGGACGCTA GAATTTAACC GTAGACAAAA GAAGAACATT 
TGGTTAGAAA CTCACATCTG GCACGCCAAG CGGTTTCATA TGGTCAAGAA GTGGGGCTAC 
TGCCTTGGGG AGAGGCCAAC AGTCAAGAGC CACAGAGCCT GCTATCGAGC CATGACGAAC 
CGGTGCCTCC TGCAGGATTT ATCCTATTAC TGTTGTTTGG AGTTGAAAGG CAAAGAGGAA 
GAAATACTAA AGGCGCTTTC TGGAATGTGT AACATAGACA CAGGGCTGAC GTTTGCAGCA 
GTTCACTGCT TGTCTGGAAA GCGCCAAGGG AGCCTTGTGC TTTATCGGGT GAATAAATAT 
CCCAGAGAAA TGCTTGGGCC TGTTACGTTT ATCTGGAAGT CCCAGAGGAC CCCGGGTGAC 
CCTTCTGAGA GCAGGCAGCT GTGGATCTGG CTGCATCCAA CCCTTAAACA GGATATCTTA 
GAGGAAATAA AAGCAGCGTG CCAGTGTGTG GAACCCATCA AATCAGCTGT CTGCATCGCT 
GACCCACTTC CAACACCATC CCAAGAAAAA AGCCAAACTG AATTGCCTGA CGAGAAAATT 
GGCAAGAAAA GAAAAAGGAA AGATGATGGA GAAAATGCTA AACCAATTAA AAAAATTATC 
GGTGATGGAA CTAGAGATCC ATGTCTACCA TACTCTTGGA TCTCTCCAAC CACAGGCATT 
ATAATCAGCG ATTTGACGAT GGAGATGAAC AGATTCCGGC TGATTGGGCC ACTTTCCCAC 
TCCATCCTAA CTGAAGCAAT AAAAGCTGCT TCTGTCCACA CTGTGGGAGA GGACACAGAG 
GAGACACCTC ACCGCTGGTG GATAGAAACC TGTAAGAAAC CTGACAGCGT TTCCCTTCAT 
TGCAGACAAG AAGCCATTTT CGAGTTGTTG GGAGGAATAA CATCACCAGC AGAAATTCCG 
GCAGGTACTA TTCTGGGACT GACAGTTGGG GATCCTCGAA TAAATTTGCC CCAAAAGAAG 
TCCAAAGCTT TGCCCAATCC AGAAAAATGC CAAGATAATG AGAAAGTTAG ACAGCTGCTT 
CTGGAGGGTG TGCCTGTGGA ATGTACGCAT AGCTTTATCT GGAACCAAGA TATCTGTAAG 
AGTGTCACAG AGAATAAAAT CTCGGATCAG GATTTAAACC GGATGAGGAG TGAATTGCTG 
GTGCCTGGGT CACAGCTTAT TTTAGGTCCC CATGAATCCA AGATACCTAT ACTTTTGATT 
CAGCAGCCAG GAAAAGTGAC TGGTGAAGAT CGACTAGGCT GGGGAAGTGG CTGGGATGTC 
CTACTCCCAA AGGGCTGGGG CATGGCTTTC TGGATTCCAT TTATTTATCG AGGTGTGAGA 
GTCGGAGGGT TGAAAGAGTC TGCAGTGCAT TCTCAGTATA AGAGGTCGCC TAATGTCCCA 
GGCGATTTTC CAGACTGCCC TGCCGGGATG CTGTTTGCGG AAGAGCAAGC TAAGAATCTT 
CTTGAAAAGT ACAAAAGACG CCCTCCTGCA AAACGGCCCA ACTACGTTAA GCTTGGCACT 
CTGGCACCTT TCTGCTGTCC CTGGGAGCAG TTAACTCAAG ACTGGGAGTC AAGAGTCCAG 
GCTTACGAAG AACCTTCTGT AGCTTCATCT CCAAATGGTA AGGAGAGTGA CCTAAGAAGA 
TCTGAGGTGC CTTGTGCTCC CATGCCTAAA AAAACTCATC AGCCATCTGA TGAAGTGGGC 
ACATCCATAG AGCACCCCAG GGAGGCAGAG GAGGTAATGG ATGCAGGGTG TCAAGAATCG 
GCAGGGCCTG AGAGGATCAC AGACCAGGAG GCCAGTGAAA ACCATGTTGC TGCCACAGGG 
AGTCACCTCT GCGTTCTCAG GAGTAGAAAA TTACTGAAGC AACTGTCAGC CTGGTGTGGG 
CCCAGTTCTG AGGATAGTCG GGGAGGCCGG CGAGCTCCCG GCAGAGGCCA GCAAGGATTG 
ACCAGAGAGG CTTGCCTGTC CATCTTGGGC CACTTCCCCA GGGCCCTGGT TTGGGTCAGC 
CTGTCCCTGC TCAGCAAGGG CAGCCCCGAG CCTCACACCA TGATCTGTGT CCCAGCCAAG 
GAGGACTTCC TCCAGCTCCA TGAGGACTGG CATTACTGTG GGCCCCAGGA ATCCAAACAC 
AGTGACCCAT TCAGGAGCAA GATCCTGAAA CAGAAAGAGA AGAAGAAAAG GGAGAAGAGG 
CAGAAGCCAG GACGTGCCTC TTCTGATGGC CCGGCGGGGG AAGAGCCCGT GGCTGGGCAG 
GAAGCTCTGA CTCTAGGGCT GTGGTCAGGC CCTCTGCCGC GTGTGACGTT GCACTGCTCC 
AGAACTCTCC TAGGCTTTGT GACTCAGGGA GATTTTTCCA TGGCTGTTGG CTGTGGAGAA 
GCCCTGGGGT TTGTTAGCTT GACAGGCTTG CTGGATATGC TGTCCAGCCA GCCTGCAGCG 
CAGAGGGGCT TAGTGCTACT GAGGCCTCCC GCCTCTCTGC AGTATCGATT TGCGAGGATT 
GCTATTGAGG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

POP1 ( NM_015029.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_055844.2 Homo sapiens POP1 homolog, ribonuclease P/MRP subunit (POP1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu07644
Clone ID Related Accession (Same CDS sequence)	NM_001145860.1 , NM_001145861.2 , NM_015029.2 , NM_001145861.1 , NM_001145860.2
Accession Version	NM_015029.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3075bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	ribonucleases P/MRP protein subunit POP1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC011529.1, D31765.1, AP003439.2 and BF511088.1. On Mar 17, 2009 this sequence version replaced NM_015029.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC011529.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145893 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCAAATG CAAAAGAAAG AAAACACGCC AAGAAAATGA GAAACCAGCC TACCAATGTG 
ACTCTGTCCT CTGGCTTTGT GGCTGACAGA GGTGTAAAGC ACCACAGTGG AGGTGAAAAA 
CCTTTCCAAG CTCAAAAACA AGAGCCTCAT CCTGGAACTT CACGACAGCG GCAAACCAGA 
GTCAACCCCC ATTCTCTGCC TGACCCTGAA GTGAATGAGC AGTCTTCCTC CAAAGGGATG 
TTTAGAAAAA AGGGAGGATG GAAAGCAGGT CCCGAGGGCA CGTCTCAGGA GATCCCCAAG 
TATATAACTG CTTCTACTTT TGCTCAAGCA CGAGCTGCTG AAATCAGTGC TATGTTAAAA 
GCTGTGACCC AGAAGTCTTC GAATTCACTG GTTTTTCAGA CTCTGCCACG GCACATGCGA 
CGAAGAGCCA TGAGCCACAA CGTCAAACGC CTTCCCAGAC GGTTACAGGA GATTGCCCAG 
AAAGAGGCGG AGAAAGCCGT ACATCAGAAA AAAGAACATT CAAAAAATAA ATGCCATAAA 
GCTCGAAGAT GTCACATGAA CCGGACGCTA GAATTTAACC GTAGACAAAA GAAGAACATT 
TGGTTAGAAA CTCACATCTG GCACGCCAAG CGGTTTCATA TGGTCAAGAA GTGGGGCTAC 
TGCCTTGGGG AGAGGCCAAC AGTCAAGAGC CACAGAGCCT GCTATCGAGC CATGACGAAC 
CGGTGCCTCC TGCAGGATTT ATCCTATTAC TGTTGTTTGG AGTTGAAAGG CAAAGAGGAA 
GAAATACTAA AGGCGCTTTC TGGAATGTGT AACATAGACA CAGGGCTGAC GTTTGCAGCA 
GTTCACTGCT TGTCTGGAAA GCGCCAAGGG AGCCTTGTGC TTTATCGGGT GAATAAATAT 
CCCAGAGAAA TGCTTGGGCC TGTTACGTTT ATCTGGAAGT CCCAGAGGAC CCCGGGTGAC 
CCTTCTGAGA GCAGGCAGCT GTGGATCTGG CTGCATCCAA CCCTTAAACA GGATATCTTA 
GAGGAAATAA AAGCAGCGTG CCAGTGTGTG GAACCCATCA AATCAGCTGT CTGCATCGCT 
GACCCACTTC CAACACCATC CCAAGAAAAA AGCCAAACTG AATTGCCTGA CGAGAAAATT 
GGCAAGAAAA GAAAAAGGAA AGATGATGGA GAAAATGCTA AACCAATTAA AAAAATTATC 
GGTGATGGAA CTAGAGATCC ATGTCTACCA TACTCTTGGA TCTCTCCAAC CACAGGCATT 
ATAATCAGCG ATTTGACGAT GGAGATGAAC AGATTCCGGC TGATTGGGCC ACTTTCCCAC 
TCCATCCTAA CTGAAGCAAT AAAAGCTGCT TCTGTCCACA CTGTGGGAGA GGACACAGAG 
GAGACACCTC ACCGCTGGTG GATAGAAACC TGTAAGAAAC CTGACAGCGT TTCCCTTCAT 
TGCAGACAAG AAGCCATTTT CGAGTTGTTG GGAGGAATAA CATCACCAGC AGAAATTCCG 
GCAGGTACTA TTCTGGGACT GACAGTTGGG GATCCTCGAA TAAATTTGCC CCAAAAGAAG 
TCCAAAGCTT TGCCCAATCC AGAAAAATGC CAAGATAATG AGAAAGTTAG ACAGCTGCTT 
CTGGAGGGTG TGCCTGTGGA ATGTACGCAT AGCTTTATCT GGAACCAAGA TATCTGTAAG 
AGTGTCACAG AGAATAAAAT CTCGGATCAG GATTTAAACC GGATGAGGAG TGAATTGCTG 
GTGCCTGGGT CACAGCTTAT TTTAGGTCCC CATGAATCCA AGATACCTAT ACTTTTGATT 
CAGCAGCCAG GAAAAGTGAC TGGTGAAGAT CGACTAGGCT GGGGAAGTGG CTGGGATGTC 
CTACTCCCAA AGGGCTGGGG CATGGCTTTC TGGATTCCAT TTATTTATCG AGGTGTGAGA 
GTCGGAGGGT TGAAAGAGTC TGCAGTGCAT TCTCAGTATA AGAGGTCGCC TAATGTCCCA 
GGCGATTTTC CAGACTGCCC TGCCGGGATG CTGTTTGCGG AAGAGCAAGC TAAGAATCTT 
CTTGAAAAGT ACAAAAGACG CCCTCCTGCA AAACGGCCCA ACTACGTTAA GCTTGGCACT 
CTGGCACCTT TCTGCTGTCC CTGGGAGCAG TTAACTCAAG ACTGGGAGTC AAGAGTCCAG 
GCTTACGAAG AACCTTCTGT AGCTTCATCT CCAAATGGTA AGGAGAGTGA CCTAAGAAGA 
TCTGAGGTGC CTTGTGCTCC CATGCCTAAA AAAACTCATC AGCCATCTGA TGAAGTGGGC 
ACATCCATAG AGCACCCCAG GGAGGCAGAG GAGGTAATGG ATGCAGGGTG TCAAGAATCG 
GCAGGGCCTG AGAGGATCAC AGACCAGGAG GCCAGTGAAA ACCATGTTGC TGCCACAGGG 
AGTCACCTCT GCGTTCTCAG GAGTAGAAAA TTACTGAAGC AACTGTCAGC CTGGTGTGGG 
CCCAGTTCTG AGGATAGTCG GGGAGGCCGG CGAGCTCCCG GCAGAGGCCA GCAAGGATTG 
ACCAGAGAGG CTTGCCTGTC CATCTTGGGC CACTTCCCCA GGGCCCTGGT TTGGGTCAGC 
CTGTCCCTGC TCAGCAAGGG CAGCCCCGAG CCTCACACCA TGATCTGTGT CCCAGCCAAG 
GAGGACTTCC TCCAGCTCCA TGAGGACTGG CATTACTGTG GGCCCCAGGA ATCCAAACAC 
AGTGACCCAT TCAGGAGCAA GATCCTGAAA CAGAAAGAGA AGAAGAAAAG GGAGAAGAGG 
CAGAAGCCAG GACGTGCCTC TTCTGATGGC CCGGCGGGGG AAGAGCCCGT GGCTGGGCAG 
GAAGCTCTGA CTCTAGGGCT GTGGTCAGGC CCTCTGCCGC GTGTGACGTT GCACTGCTCC 
AGAACTCTCC TAGGCTTTGT GACTCAGGGA GATTTTTCCA TGGCTGTTGG CTGTGGAGAA 
GCCCTGGGGT TTGTTAGCTT GACAGGCTTG CTGGATATGC TGTCCAGCCA GCCTGCAGCG 
CAGAGGGGCT TAGTGCTACT GAGGCCTCCC GCCTCTCTGC AGTATCGATT TGCGAGGATT 
GCTATTGAGG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055844.2
CDS	29..3103
Translation	MSNAKERKHAKKMRNQPTNVTLSSGFVADRGVKHHSGGEKPFQAQKQEPHPGTSRQRQTRVNPHSLPDPEVNEQSSSKGMFRKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQKSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEIAQKEAEKAVHQKKEHSKNKCHKARRCHMNRTLEFNRRQKKNIWLETHIWHAKRFHMVKKWGYCLGERPTVKSHRACYRAMTNRCLLQDLSYYCCLELKGKEEEILKALSGMCNIDTGLTFAAVHCLSGKRQGSLVLYRVNKYPREMLGPVTFIWKSQRTPGDPSESRQLWIWLHPTLKQDILEEIKAACQCVEPIKSAVCIADPLPTPSQEKSQTELPDEKIGKKRKRKDDGENAKPIKKIIGDGTRDPCLPYSWISPTTGIIISDLTMEMNRFRLIGPLSHSILTEAIKAASVHTVGEDTEETPHRWWIETCKKPDSVSLHCRQEAIFELLGGITSPAEIPAGTILGLTVGDPRINLPQKKSKALPNPEKCQDNEKVRQLLLEGVPVECTHSFIWNQDICKSVTENKISDQDLNRMRSELLVPGSQLILGPHESKIPILLIQQPGKVTGEDRLGWGSGWDVLLPKGWGMAFWIPFIYRGVRVGGLKESAVHSQYKRSPNVPGDFPDCPAGMLFAEEQAKNLLEKYKRRPPAKRPNYVKLGTLAPFCCPWEQLTQDWESRVQAYEEPSVASSPNGKESDLRRSEVPCAPMPKKTHQPSDEVGTSIEHPREAEEVMDAGCQESAGPERITDQEASENHVAATGSHLCVLRSRKLLKQLSAWCGPSSEDSRGGRRAPGRGQQGLTREACLSILGHFPRALVWVSLSLLSKGSPEPHTMICVPAKEDFLQLHEDWHYCGPQESKHSDPFRSKILKQKEKKKREKRQKPGRASSDGPAGEEPVAGQEALTLGLWSGPLPRVTLHCSRTLLGFVTQGDFSMAVGCGEALGFVSLTGLLDMLSSQPAAQRGLVLLRPPASLQYRFARIAIEV

Target ORF information:

RefSeq Version	NM_015029.2
Organism	Homo sapiens(human)
Definition	Homo sapiens POP1 homolog, ribonuclease P/MRP subunit (POP1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015029.2

ORF Insert Sequence:

ATGTCAAATG CAAAAGAAAG AAAACACGCC AAGAAAATGA GAAACCAGCC TACCAATGTG 
ACTCTGTCCT CTGGCTTTGT GGCTGACAGA GGTGTAAAGC ACCACAGTGG AGGTGAAAAA 
CCTTTCCAAG CTCAAAAACA AGAGCCTCAT CCTGGAACTT CACGACAGCG GCAAACCAGA 
GTCAACCCCC ATTCTCTGCC TGACCCTGAA GTGAATGAGC AGTCTTCCTC CAAAGGGATG 
TTTAGAAAAA AGGGAGGATG GAAAGCAGGT CCCGAGGGCA CGTCTCAGGA GATCCCCAAG 
TATATAACTG CTTCTACTTT TGCTCAAGCA CGAGCTGCTG AAATCAGTGC TATGTTAAAA 
GCTGTGACCC AGAAGTCTTC GAATTCACTG GTTTTTCAGA CTCTGCCACG GCACATGCGA 
CGAAGAGCCA TGAGCCACAA CGTCAAACGC CTTCCCAGAC GGTTACAGGA GATTGCCCAG 
AAAGAGGCGG AGAAAGCCGT ACATCAGAAA AAAGAACATT CAAAAAATAA ATGCCATAAA 
GCTCGAAGAT GTCACATGAA CCGGACGCTA GAATTTAACC GTAGACAAAA GAAGAACATT 
TGGTTAGAAA CTCACATCTG GCACGCCAAG CGGTTTCATA TGGTCAAGAA GTGGGGCTAC 
TGCCTTGGGG AGAGGCCAAC AGTCAAGAGC CACAGAGCCT GCTATCGAGC CATGACGAAC 
CGGTGCCTCC TGCAGGATTT ATCCTATTAC TGTTGTTTGG AGTTGAAAGG CAAAGAGGAA 
GAAATACTAA AGGCGCTTTC TGGAATGTGT AACATAGACA CAGGGCTGAC GTTTGCAGCA 
GTTCACTGCT TGTCTGGAAA GCGCCAAGGG AGCCTTGTGC TTTATCGGGT GAATAAATAT 
CCCAGAGAAA TGCTTGGGCC TGTTACGTTT ATCTGGAAGT CCCAGAGGAC CCCGGGTGAC 
CCTTCTGAGA GCAGGCAGCT GTGGATCTGG CTGCATCCAA CCCTTAAACA GGATATCTTA 
GAGGAAATAA AAGCAGCGTG CCAGTGTGTG GAACCCATCA AATCAGCTGT CTGCATCGCT 
GACCCACTTC CAACACCATC CCAAGAAAAA AGCCAAACTG AATTGCCTGA CGAGAAAATT 
GGCAAGAAAA GAAAAAGGAA AGATGATGGA GAAAATGCTA AACCAATTAA AAAAATTATC 
GGTGATGGAA CTAGAGATCC ATGTCTACCA TACTCTTGGA TCTCTCCAAC CACAGGCATT 
ATAATCAGCG ATTTGACGAT GGAGATGAAC AGATTCCGGC TGATTGGGCC ACTTTCCCAC 
TCCATCCTAA CTGAAGCAAT AAAAGCTGCT TCTGTCCACA CTGTGGGAGA GGACACAGAG 
GAGACACCTC ACCGCTGGTG GATAGAAACC TGTAAGAAAC CTGACAGCGT TTCCCTTCAT 
TGCAGACAAG AAGCCATTTT CGAGTTGTTG GGAGGAATAA CATCACCAGC AGAAATTCCG 
GCAGGTACTA TTCTGGGACT GACAGTTGGG GATCCTCGAA TAAATTTGCC CCAAAAGAAG 
TCCAAAGCTT TGCCCAATCC AGAAAAATGC CAAGATAATG AGAAAGTTAG ACAGCTGCTT 
CTGGAGGGTG TGCCTGTGGA ATGTACGCAT AGCTTTATCT GGAACCAAGA TATCTGTAAG 
AGTGTCACAG AGAATAAAAT CTCGGATCAG GATTTAAACC GGATGAGGAG TGAATTGCTG 
GTGCCTGGGT CACAGCTTAT TTTAGGTCCC CATGAATCCA AGATACCTAT ACTTTTGATT 
CAGCAGCCAG GAAAAGTGAC TGGTGAAGAT CGACTAGGCT GGGGAAGTGG CTGGGATGTC 
CTACTCCCAA AGGGCTGGGG CATGGCTTTC TGGATTCCAT TTATTTATCG AGGTGTGAGA 
GTCGGAGGGT TGAAAGAGTC TGCAGTGCAT TCTCAGTATA AGAGGTCGCC TAATGTCCCA 
GGCGATTTTC CAGACTGCCC TGCCGGGATG CTGTTTGCGG AAGAGCAAGC TAAGAATCTT 
CTTGAAAAGT ACAAAAGACG CCCTCCTGCA AAACGGCCCA ACTACGTTAA GCTTGGCACT 
CTGGCACCTT TCTGCTGTCC CTGGGAGCAG TTAACTCAAG ACTGGGAGTC AAGAGTCCAG 
GCTTACGAAG AACCTTCTGT AGCTTCATCT CCAAATGGTA AGGAGAGTGA CCTAAGAAGA 
TCTGAGGTGC CTTGTGCTCC CATGCCTAAA AAAACTCATC AGCCATCTGA TGAAGTGGGC 
ACATCCATAG AGCACCCCAG GGAGGCAGAG GAGGTAATGG ATGCAGGGTG TCAAGAATCG 
GCAGGGCCTG AGAGGATCAC AGACCAGGAG GCCAGTGAAA ACCATGTTGC TGCCACAGGG 
AGTCACCTCT GCGTTCTCAG GAGTAGAAAA TTACTGAAGC AACTGTCAGC CTGGTGTGGG 
CCCAGTTCTG AGGATAGTCG GGGAGGCCGG CGAGCTCCCG GCAGAGGCCA GCAAGGATTG 
ACCAGAGAGG CTTGCCTGTC CATCTTGGGC CACTTCCCCA GGGCCCTGGT TTGGGTCAGC 
CTGTCCCTGC TCAGCAAGGG CAGCCCCGAG CCTCACACCA TGATCTGTGT CCCAGCCAAG 
GAGGACTTCC TCCAGCTCCA TGAGGACTGG CATTACTGTG GGCCCCAGGA ATCCAAACAC 
AGTGACCCAT TCAGGAGCAA GATCCTGAAA CAGAAAGAGA AGAAGAAAAG GGAGAAGAGG 
CAGAAGCCAG GACGTGCCTC TTCTGATGGC CCGGCGGGGG AAGAGCCCGT GGCTGGGCAG 
GAAGCTCTGA CTCTAGGGCT GTGGTCAGGC CCTCTGCCGC GTGTGACGTT GCACTGCTCC 
AGAACTCTCC TAGGCTTTGT GACTCAGGGA GATTTTTCCA TGGCTGTTGG CTGTGGAGAA 
GCCCTGGGGT TTGTTAGCTT GACAGGCTTG CTGGATATGC TGTCCAGCCA GCCTGCAGCG 
CAGAGGGGCT TAGTGCTACT GAGGCCTCCC GCCTCTCTGC AGTATCGATT TGCGAGGATT 
GCTATTGAGG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

POP1 ( NM_001145861.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001139333.1 Homo sapiens POP1 homolog, ribonuclease P/MRP subunit (POP1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu07644
Clone ID Related Accession (Same CDS sequence)	NM_001145860.1 , NM_001145861.2 , NM_015029.2 , NM_001145861.1 , NM_001145860.2
Accession Version	NM_001145861.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3075bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-19
Organism	Homo sapiens(human)
Product	ribonucleases P/MRP protein subunit POP1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP280616.1, BP249298.1, AK291434.1, D31765.1, AP003439.2 and BF511088.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: SRR1803613.265777.1, SRR1803616.101407.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGTCAAATG CAAAAGAAAG AAAACACGCC AAGAAAATGA GAAACCAGCC TACCAATGTG 
ACTCTGTCCT CTGGCTTTGT GGCTGACAGA GGTGTAAAGC ACCACAGTGG AGGTGAAAAA 
CCTTTCCAAG CTCAAAAACA AGAGCCTCAT CCTGGAACTT CACGACAGCG GCAAACCAGA 
GTCAACCCCC ATTCTCTGCC TGACCCTGAA GTGAATGAGC AGTCTTCCTC CAAAGGGATG 
TTTAGAAAAA AGGGAGGATG GAAAGCAGGT CCCGAGGGCA CGTCTCAGGA GATCCCCAAG 
TATATAACTG CTTCTACTTT TGCTCAAGCA CGAGCTGCTG AAATCAGTGC TATGTTAAAA 
GCTGTGACCC AGAAGTCTTC GAATTCACTG GTTTTTCAGA CTCTGCCACG GCACATGCGA 
CGAAGAGCCA TGAGCCACAA CGTCAAACGC CTTCCCAGAC GGTTACAGGA GATTGCCCAG 
AAAGAGGCGG AGAAAGCCGT ACATCAGAAA AAAGAACATT CAAAAAATAA ATGCCATAAA 
GCTCGAAGAT GTCACATGAA CCGGACGCTA GAATTTAACC GTAGACAAAA GAAGAACATT 
TGGTTAGAAA CTCACATCTG GCACGCCAAG CGGTTTCATA TGGTCAAGAA GTGGGGCTAC 
TGCCTTGGGG AGAGGCCAAC AGTCAAGAGC CACAGAGCCT GCTATCGAGC CATGACGAAC 
CGGTGCCTCC TGCAGGATTT ATCCTATTAC TGTTGTTTGG AGTTGAAAGG CAAAGAGGAA 
GAAATACTAA AGGCGCTTTC TGGAATGTGT AACATAGACA CAGGGCTGAC GTTTGCAGCA 
GTTCACTGCT TGTCTGGAAA GCGCCAAGGG AGCCTTGTGC TTTATCGGGT GAATAAATAT 
CCCAGAGAAA TGCTTGGGCC TGTTACGTTT ATCTGGAAGT CCCAGAGGAC CCCGGGTGAC 
CCTTCTGAGA GCAGGCAGCT GTGGATCTGG CTGCATCCAA CCCTTAAACA GGATATCTTA 
GAGGAAATAA AAGCAGCGTG CCAGTGTGTG GAACCCATCA AATCAGCTGT CTGCATCGCT 
GACCCACTTC CAACACCATC CCAAGAAAAA AGCCAAACTG AATTGCCTGA CGAGAAAATT 
GGCAAGAAAA GAAAAAGGAA AGATGATGGA GAAAATGCTA AACCAATTAA AAAAATTATC 
GGTGATGGAA CTAGAGATCC ATGTCTACCA TACTCTTGGA TCTCTCCAAC CACAGGCATT 
ATAATCAGCG ATTTGACGAT GGAGATGAAC AGATTCCGGC TGATTGGGCC ACTTTCCCAC 
TCCATCCTAA CTGAAGCAAT AAAAGCTGCT TCTGTCCACA CTGTGGGAGA GGACACAGAG 
GAGACACCTC ACCGCTGGTG GATAGAAACC TGTAAGAAAC CTGACAGCGT TTCCCTTCAT 
TGCAGACAAG AAGCCATTTT CGAGTTGTTG GGAGGAATAA CATCACCAGC AGAAATTCCG 
GCAGGTACTA TTCTGGGACT GACAGTTGGG GATCCTCGAA TAAATTTGCC CCAAAAGAAG 
TCCAAAGCTT TGCCCAATCC AGAAAAATGC CAAGATAATG AGAAAGTTAG ACAGCTGCTT 
CTGGAGGGTG TGCCTGTGGA ATGTACGCAT AGCTTTATCT GGAACCAAGA TATCTGTAAG 
AGTGTCACAG AGAATAAAAT CTCGGATCAG GATTTAAACC GGATGAGGAG TGAATTGCTG 
GTGCCTGGGT CACAGCTTAT TTTAGGTCCC CATGAATCCA AGATACCTAT ACTTTTGATT 
CAGCAGCCAG GAAAAGTGAC TGGTGAAGAT CGACTAGGCT GGGGAAGTGG CTGGGATGTC 
CTACTCCCAA AGGGCTGGGG CATGGCTTTC TGGATTCCAT TTATTTATCG AGGTGTGAGA 
GTCGGAGGGT TGAAAGAGTC TGCAGTGCAT TCTCAGTATA AGAGGTCGCC TAATGTCCCA 
GGCGATTTTC CAGACTGCCC TGCCGGGATG CTGTTTGCGG AAGAGCAAGC TAAGAATCTT 
CTTGAAAAGT ACAAAAGACG CCCTCCTGCA AAACGGCCCA ACTACGTTAA GCTTGGCACT 
CTGGCACCTT TCTGCTGTCC CTGGGAGCAG TTAACTCAAG ACTGGGAGTC AAGAGTCCAG 
GCTTACGAAG AACCTTCTGT AGCTTCATCT CCAAATGGTA AGGAGAGTGA CCTAAGAAGA 
TCTGAGGTGC CTTGTGCTCC CATGCCTAAA AAAACTCATC AGCCATCTGA TGAAGTGGGC 
ACATCCATAG AGCACCCCAG GGAGGCAGAG GAGGTAATGG ATGCAGGGTG TCAAGAATCG 
GCAGGGCCTG AGAGGATCAC AGACCAGGAG GCCAGTGAAA ACCATGTTGC TGCCACAGGG 
AGTCACCTCT GCGTTCTCAG GAGTAGAAAA TTACTGAAGC AACTGTCAGC CTGGTGTGGG 
CCCAGTTCTG AGGATAGTCG GGGAGGCCGG CGAGCTCCCG GCAGAGGCCA GCAAGGATTG 
ACCAGAGAGG CTTGCCTGTC CATCTTGGGC CACTTCCCCA GGGCCCTGGT TTGGGTCAGC 
CTGTCCCTGC TCAGCAAGGG CAGCCCCGAG CCTCACACCA TGATCTGTGT CCCAGCCAAG 
GAGGACTTCC TCCAGCTCCA TGAGGACTGG CATTACTGTG GGCCCCAGGA ATCCAAACAC 
AGTGACCCAT TCAGGAGCAA GATCCTGAAA CAGAAAGAGA AGAAGAAAAG GGAGAAGAGG 
CAGAAGCCAG GACGTGCCTC TTCTGATGGC CCGGCGGGGG AAGAGCCCGT GGCTGGGCAG 
GAAGCTCTGA CTCTAGGGCT GTGGTCAGGC CCTCTGCCGC GTGTGACGTT GCACTGCTCC 
AGAACTCTCC TAGGCTTTGT GACTCAGGGA GATTTTTCCA TGGCTGTTGG CTGTGGAGAA 
GCCCTGGGGT TTGTTAGCTT GACAGGCTTG CTGGATATGC TGTCCAGCCA GCCTGCAGCG 
CAGAGGGGCT TAGTGCTACT GAGGCCTCCC GCCTCTCTGC AGTATCGATT TGCGAGGATT 
GCTATTGAGG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001139333.1
CDS	41..3115
Translation	MSNAKERKHAKKMRNQPTNVTLSSGFVADRGVKHHSGGEKPFQAQKQEPHPGTSRQRQTRVNPHSLPDPEVNEQSSSKGMFRKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQKSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEIAQKEAEKAVHQKKEHSKNKCHKARRCHMNRTLEFNRRQKKNIWLETHIWHAKRFHMVKKWGYCLGERPTVKSHRACYRAMTNRCLLQDLSYYCCLELKGKEEEILKALSGMCNIDTGLTFAAVHCLSGKRQGSLVLYRVNKYPREMLGPVTFIWKSQRTPGDPSESRQLWIWLHPTLKQDILEEIKAACQCVEPIKSAVCIADPLPTPSQEKSQTELPDEKIGKKRKRKDDGENAKPIKKIIGDGTRDPCLPYSWISPTTGIIISDLTMEMNRFRLIGPLSHSILTEAIKAASVHTVGEDTEETPHRWWIETCKKPDSVSLHCRQEAIFELLGGITSPAEIPAGTILGLTVGDPRINLPQKKSKALPNPEKCQDNEKVRQLLLEGVPVECTHSFIWNQDICKSVTENKISDQDLNRMRSELLVPGSQLILGPHESKIPILLIQQPGKVTGEDRLGWGSGWDVLLPKGWGMAFWIPFIYRGVRVGGLKESAVHSQYKRSPNVPGDFPDCPAGMLFAEEQAKNLLEKYKRRPPAKRPNYVKLGTLAPFCCPWEQLTQDWESRVQAYEEPSVASSPNGKESDLRRSEVPCAPMPKKTHQPSDEVGTSIEHPREAEEVMDAGCQESAGPERITDQEASENHVAATGSHLCVLRSRKLLKQLSAWCGPSSEDSRGGRRAPGRGQQGLTREACLSILGHFPRALVWVSLSLLSKGSPEPHTMICVPAKEDFLQLHEDWHYCGPQESKHSDPFRSKILKQKEKKKREKRQKPGRASSDGPAGEEPVAGQEALTLGLWSGPLPRVTLHCSRTLLGFVTQGDFSMAVGCGEALGFVSLTGLLDMLSSQPAAQRGLVLLRPPASLQYRFARIAIEV

Target ORF information:

RefSeq Version	NM_001145861.1
Organism	Homo sapiens(human)
Definition	Homo sapiens POP1 homolog, ribonuclease P/MRP subunit (POP1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145861.1

ORF Insert Sequence:

ATGTCAAATG CAAAAGAAAG AAAACACGCC AAGAAAATGA GAAACCAGCC TACCAATGTG 
ACTCTGTCCT CTGGCTTTGT GGCTGACAGA GGTGTAAAGC ACCACAGTGG AGGTGAAAAA 
CCTTTCCAAG CTCAAAAACA AGAGCCTCAT CCTGGAACTT CACGACAGCG GCAAACCAGA 
GTCAACCCCC ATTCTCTGCC TGACCCTGAA GTGAATGAGC AGTCTTCCTC CAAAGGGATG 
TTTAGAAAAA AGGGAGGATG GAAAGCAGGT CCCGAGGGCA CGTCTCAGGA GATCCCCAAG 
TATATAACTG CTTCTACTTT TGCTCAAGCA CGAGCTGCTG AAATCAGTGC TATGTTAAAA 
GCTGTGACCC AGAAGTCTTC GAATTCACTG GTTTTTCAGA CTCTGCCACG GCACATGCGA 
CGAAGAGCCA TGAGCCACAA CGTCAAACGC CTTCCCAGAC GGTTACAGGA GATTGCCCAG 
AAAGAGGCGG AGAAAGCCGT ACATCAGAAA AAAGAACATT CAAAAAATAA ATGCCATAAA 
GCTCGAAGAT GTCACATGAA CCGGACGCTA GAATTTAACC GTAGACAAAA GAAGAACATT 
TGGTTAGAAA CTCACATCTG GCACGCCAAG CGGTTTCATA TGGTCAAGAA GTGGGGCTAC 
TGCCTTGGGG AGAGGCCAAC AGTCAAGAGC CACAGAGCCT GCTATCGAGC CATGACGAAC 
CGGTGCCTCC TGCAGGATTT ATCCTATTAC TGTTGTTTGG AGTTGAAAGG CAAAGAGGAA 
GAAATACTAA AGGCGCTTTC TGGAATGTGT AACATAGACA CAGGGCTGAC GTTTGCAGCA 
GTTCACTGCT TGTCTGGAAA GCGCCAAGGG AGCCTTGTGC TTTATCGGGT GAATAAATAT 
CCCAGAGAAA TGCTTGGGCC TGTTACGTTT ATCTGGAAGT CCCAGAGGAC CCCGGGTGAC 
CCTTCTGAGA GCAGGCAGCT GTGGATCTGG CTGCATCCAA CCCTTAAACA GGATATCTTA 
GAGGAAATAA AAGCAGCGTG CCAGTGTGTG GAACCCATCA AATCAGCTGT CTGCATCGCT 
GACCCACTTC CAACACCATC CCAAGAAAAA AGCCAAACTG AATTGCCTGA CGAGAAAATT 
GGCAAGAAAA GAAAAAGGAA AGATGATGGA GAAAATGCTA AACCAATTAA AAAAATTATC 
GGTGATGGAA CTAGAGATCC ATGTCTACCA TACTCTTGGA TCTCTCCAAC CACAGGCATT 
ATAATCAGCG ATTTGACGAT GGAGATGAAC AGATTCCGGC TGATTGGGCC ACTTTCCCAC 
TCCATCCTAA CTGAAGCAAT AAAAGCTGCT TCTGTCCACA CTGTGGGAGA GGACACAGAG 
GAGACACCTC ACCGCTGGTG GATAGAAACC TGTAAGAAAC CTGACAGCGT TTCCCTTCAT 
TGCAGACAAG AAGCCATTTT CGAGTTGTTG GGAGGAATAA CATCACCAGC AGAAATTCCG 
GCAGGTACTA TTCTGGGACT GACAGTTGGG GATCCTCGAA TAAATTTGCC CCAAAAGAAG 
TCCAAAGCTT TGCCCAATCC AGAAAAATGC CAAGATAATG AGAAAGTTAG ACAGCTGCTT 
CTGGAGGGTG TGCCTGTGGA ATGTACGCAT AGCTTTATCT GGAACCAAGA TATCTGTAAG 
AGTGTCACAG AGAATAAAAT CTCGGATCAG GATTTAAACC GGATGAGGAG TGAATTGCTG 
GTGCCTGGGT CACAGCTTAT TTTAGGTCCC CATGAATCCA AGATACCTAT ACTTTTGATT 
CAGCAGCCAG GAAAAGTGAC TGGTGAAGAT CGACTAGGCT GGGGAAGTGG CTGGGATGTC 
CTACTCCCAA AGGGCTGGGG CATGGCTTTC TGGATTCCAT TTATTTATCG AGGTGTGAGA 
GTCGGAGGGT TGAAAGAGTC TGCAGTGCAT TCTCAGTATA AGAGGTCGCC TAATGTCCCA 
GGCGATTTTC CAGACTGCCC TGCCGGGATG CTGTTTGCGG AAGAGCAAGC TAAGAATCTT 
CTTGAAAAGT ACAAAAGACG CCCTCCTGCA AAACGGCCCA ACTACGTTAA GCTTGGCACT 
CTGGCACCTT TCTGCTGTCC CTGGGAGCAG TTAACTCAAG ACTGGGAGTC AAGAGTCCAG 
GCTTACGAAG AACCTTCTGT AGCTTCATCT CCAAATGGTA AGGAGAGTGA CCTAAGAAGA 
TCTGAGGTGC CTTGTGCTCC CATGCCTAAA AAAACTCATC AGCCATCTGA TGAAGTGGGC 
ACATCCATAG AGCACCCCAG GGAGGCAGAG GAGGTAATGG ATGCAGGGTG TCAAGAATCG 
GCAGGGCCTG AGAGGATCAC AGACCAGGAG GCCAGTGAAA ACCATGTTGC TGCCACAGGG 
AGTCACCTCT GCGTTCTCAG GAGTAGAAAA TTACTGAAGC AACTGTCAGC CTGGTGTGGG 
CCCAGTTCTG AGGATAGTCG GGGAGGCCGG CGAGCTCCCG GCAGAGGCCA GCAAGGATTG 
ACCAGAGAGG CTTGCCTGTC CATCTTGGGC CACTTCCCCA GGGCCCTGGT TTGGGTCAGC 
CTGTCCCTGC TCAGCAAGGG CAGCCCCGAG CCTCACACCA TGATCTGTGT CCCAGCCAAG 
GAGGACTTCC TCCAGCTCCA TGAGGACTGG CATTACTGTG GGCCCCAGGA ATCCAAACAC 
AGTGACCCAT TCAGGAGCAA GATCCTGAAA CAGAAAGAGA AGAAGAAAAG GGAGAAGAGG 
CAGAAGCCAG GACGTGCCTC TTCTGATGGC CCGGCGGGGG AAGAGCCCGT GGCTGGGCAG 
GAAGCTCTGA CTCTAGGGCT GTGGTCAGGC CCTCTGCCGC GTGTGACGTT GCACTGCTCC 
AGAACTCTCC TAGGCTTTGT GACTCAGGGA GATTTTTCCA TGGCTGTTGG CTGTGGAGAA 
GCCCTGGGGT TTGTTAGCTT GACAGGCTTG CTGGATATGC TGTCCAGCCA GCCTGCAGCG 
CAGAGGGGCT TAGTGCTACT GAGGCCTCCC GCCTCTCTGC AGTATCGATT TGCGAGGATT 
GCTATTGAGG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

POP1 ( NM_001145860.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001139332.1 Homo sapiens POP1 homolog, ribonuclease P/MRP subunit (POP1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu07644
Clone ID Related Accession (Same CDS sequence)	NM_001145860.1 , NM_001145861.2 , NM_015029.2 , NM_001145861.1 , NM_001145860.2
Accession Version	NM_001145860.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3075bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	ribonucleases P/MRP protein subunit POP1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from X99302.1, AK291434.1, D31765.1, AP003439.2 and BF511088.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_001145860.1. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.265777.1, SRR1803616.101407.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000401707.7/ ENSP00000385787.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCAAATG CAAAAGAAAG AAAACACGCC AAGAAAATGA GAAACCAGCC TACCAATGTG 
ACTCTGTCCT CTGGCTTTGT GGCTGACAGA GGTGTAAAGC ACCACAGTGG AGGTGAAAAA 
CCTTTCCAAG CTCAAAAACA AGAGCCTCAT CCTGGAACTT CACGACAGCG GCAAACCAGA 
GTCAACCCCC ATTCTCTGCC TGACCCTGAA GTGAATGAGC AGTCTTCCTC CAAAGGGATG 
TTTAGAAAAA AGGGAGGATG GAAAGCAGGT CCCGAGGGCA CGTCTCAGGA GATCCCCAAG 
TATATAACTG CTTCTACTTT TGCTCAAGCA CGAGCTGCTG AAATCAGTGC TATGTTAAAA 
GCTGTGACCC AGAAGTCTTC GAATTCACTG GTTTTTCAGA CTCTGCCACG GCACATGCGA 
CGAAGAGCCA TGAGCCACAA CGTCAAACGC CTTCCCAGAC GGTTACAGGA GATTGCCCAG 
AAAGAGGCGG AGAAAGCCGT ACATCAGAAA AAAGAACATT CAAAAAATAA ATGCCATAAA 
GCTCGAAGAT GTCACATGAA CCGGACGCTA GAATTTAACC GTAGACAAAA GAAGAACATT 
TGGTTAGAAA CTCACATCTG GCACGCCAAG CGGTTTCATA TGGTCAAGAA GTGGGGCTAC 
TGCCTTGGGG AGAGGCCAAC AGTCAAGAGC CACAGAGCCT GCTATCGAGC CATGACGAAC 
CGGTGCCTCC TGCAGGATTT ATCCTATTAC TGTTGTTTGG AGTTGAAAGG CAAAGAGGAA 
GAAATACTAA AGGCGCTTTC TGGAATGTGT AACATAGACA CAGGGCTGAC GTTTGCAGCA 
GTTCACTGCT TGTCTGGAAA GCGCCAAGGG AGCCTTGTGC TTTATCGGGT GAATAAATAT 
CCCAGAGAAA TGCTTGGGCC TGTTACGTTT ATCTGGAAGT CCCAGAGGAC CCCGGGTGAC 
CCTTCTGAGA GCAGGCAGCT GTGGATCTGG CTGCATCCAA CCCTTAAACA GGATATCTTA 
GAGGAAATAA AAGCAGCGTG CCAGTGTGTG GAACCCATCA AATCAGCTGT CTGCATCGCT 
GACCCACTTC CAACACCATC CCAAGAAAAA AGCCAAACTG AATTGCCTGA CGAGAAAATT 
GGCAAGAAAA GAAAAAGGAA AGATGATGGA GAAAATGCTA AACCAATTAA AAAAATTATC 
GGTGATGGAA CTAGAGATCC ATGTCTACCA TACTCTTGGA TCTCTCCAAC CACAGGCATT 
ATAATCAGCG ATTTGACGAT GGAGATGAAC AGATTCCGGC TGATTGGGCC ACTTTCCCAC 
TCCATCCTAA CTGAAGCAAT AAAAGCTGCT TCTGTCCACA CTGTGGGAGA GGACACAGAG 
GAGACACCTC ACCGCTGGTG GATAGAAACC TGTAAGAAAC CTGACAGCGT TTCCCTTCAT 
TGCAGACAAG AAGCCATTTT CGAGTTGTTG GGAGGAATAA CATCACCAGC AGAAATTCCG 
GCAGGTACTA TTCTGGGACT GACAGTTGGG GATCCTCGAA TAAATTTGCC CCAAAAGAAG 
TCCAAAGCTT TGCCCAATCC AGAAAAATGC CAAGATAATG AGAAAGTTAG ACAGCTGCTT 
CTGGAGGGTG TGCCTGTGGA ATGTACGCAT AGCTTTATCT GGAACCAAGA TATCTGTAAG 
AGTGTCACAG AGAATAAAAT CTCGGATCAG GATTTAAACC GGATGAGGAG TGAATTGCTG 
GTGCCTGGGT CACAGCTTAT TTTAGGTCCC CATGAATCCA AGATACCTAT ACTTTTGATT 
CAGCAGCCAG GAAAAGTGAC TGGTGAAGAT CGACTAGGCT GGGGAAGTGG CTGGGATGTC 
CTACTCCCAA AGGGCTGGGG CATGGCTTTC TGGATTCCAT TTATTTATCG AGGTGTGAGA 
GTCGGAGGGT TGAAAGAGTC TGCAGTGCAT TCTCAGTATA AGAGGTCGCC TAATGTCCCA 
GGCGATTTTC CAGACTGCCC TGCCGGGATG CTGTTTGCGG AAGAGCAAGC TAAGAATCTT 
CTTGAAAAGT ACAAAAGACG CCCTCCTGCA AAACGGCCCA ACTACGTTAA GCTTGGCACT 
CTGGCACCTT TCTGCTGTCC CTGGGAGCAG TTAACTCAAG ACTGGGAGTC AAGAGTCCAG 
GCTTACGAAG AACCTTCTGT AGCTTCATCT CCAAATGGTA AGGAGAGTGA CCTAAGAAGA 
TCTGAGGTGC CTTGTGCTCC CATGCCTAAA AAAACTCATC AGCCATCTGA TGAAGTGGGC 
ACATCCATAG AGCACCCCAG GGAGGCAGAG GAGGTAATGG ATGCAGGGTG TCAAGAATCG 
GCAGGGCCTG AGAGGATCAC AGACCAGGAG GCCAGTGAAA ACCATGTTGC TGCCACAGGG 
AGTCACCTCT GCGTTCTCAG GAGTAGAAAA TTACTGAAGC AACTGTCAGC CTGGTGTGGG 
CCCAGTTCTG AGGATAGTCG GGGAGGCCGG CGAGCTCCCG GCAGAGGCCA GCAAGGATTG 
ACCAGAGAGG CTTGCCTGTC CATCTTGGGC CACTTCCCCA GGGCCCTGGT TTGGGTCAGC 
CTGTCCCTGC TCAGCAAGGG CAGCCCCGAG CCTCACACCA TGATCTGTGT CCCAGCCAAG 
GAGGACTTCC TCCAGCTCCA TGAGGACTGG CATTACTGTG GGCCCCAGGA ATCCAAACAC 
AGTGACCCAT TCAGGAGCAA GATCCTGAAA CAGAAAGAGA AGAAGAAAAG GGAGAAGAGG 
CAGAAGCCAG GACGTGCCTC TTCTGATGGC CCGGCGGGGG AAGAGCCCGT GGCTGGGCAG 
GAAGCTCTGA CTCTAGGGCT GTGGTCAGGC CCTCTGCCGC GTGTGACGTT GCACTGCTCC 
AGAACTCTCC TAGGCTTTGT GACTCAGGGA GATTTTTCCA TGGCTGTTGG CTGTGGAGAA 
GCCCTGGGGT TTGTTAGCTT GACAGGCTTG CTGGATATGC TGTCCAGCCA GCCTGCAGCG 
CAGAGGGGCT TAGTGCTACT GAGGCCTCCC GCCTCTCTGC AGTATCGATT TGCGAGGATT 
GCTATTGAGG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001139332.1
CDS	101..3175
Translation	MSNAKERKHAKKMRNQPTNVTLSSGFVADRGVKHHSGGEKPFQAQKQEPHPGTSRQRQTRVNPHSLPDPEVNEQSSSKGMFRKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQKSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEIAQKEAEKAVHQKKEHSKNKCHKARRCHMNRTLEFNRRQKKNIWLETHIWHAKRFHMVKKWGYCLGERPTVKSHRACYRAMTNRCLLQDLSYYCCLELKGKEEEILKALSGMCNIDTGLTFAAVHCLSGKRQGSLVLYRVNKYPREMLGPVTFIWKSQRTPGDPSESRQLWIWLHPTLKQDILEEIKAACQCVEPIKSAVCIADPLPTPSQEKSQTELPDEKIGKKRKRKDDGENAKPIKKIIGDGTRDPCLPYSWISPTTGIIISDLTMEMNRFRLIGPLSHSILTEAIKAASVHTVGEDTEETPHRWWIETCKKPDSVSLHCRQEAIFELLGGITSPAEIPAGTILGLTVGDPRINLPQKKSKALPNPEKCQDNEKVRQLLLEGVPVECTHSFIWNQDICKSVTENKISDQDLNRMRSELLVPGSQLILGPHESKIPILLIQQPGKVTGEDRLGWGSGWDVLLPKGWGMAFWIPFIYRGVRVGGLKESAVHSQYKRSPNVPGDFPDCPAGMLFAEEQAKNLLEKYKRRPPAKRPNYVKLGTLAPFCCPWEQLTQDWESRVQAYEEPSVASSPNGKESDLRRSEVPCAPMPKKTHQPSDEVGTSIEHPREAEEVMDAGCQESAGPERITDQEASENHVAATGSHLCVLRSRKLLKQLSAWCGPSSEDSRGGRRAPGRGQQGLTREACLSILGHFPRALVWVSLSLLSKGSPEPHTMICVPAKEDFLQLHEDWHYCGPQESKHSDPFRSKILKQKEKKKREKRQKPGRASSDGPAGEEPVAGQEALTLGLWSGPLPRVTLHCSRTLLGFVTQGDFSMAVGCGEALGFVSLTGLLDMLSSQPAAQRGLVLLRPPASLQYRFARIAIEV

Target ORF information:

RefSeq Version	NM_001145860.2
Organism	Homo sapiens(human)
Definition	Homo sapiens POP1 homolog, ribonuclease P/MRP subunit (POP1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145860.2

ORF Insert Sequence:

ATGTCAAATG CAAAAGAAAG AAAACACGCC AAGAAAATGA GAAACCAGCC TACCAATGTG 
ACTCTGTCCT CTGGCTTTGT GGCTGACAGA GGTGTAAAGC ACCACAGTGG AGGTGAAAAA 
CCTTTCCAAG CTCAAAAACA AGAGCCTCAT CCTGGAACTT CACGACAGCG GCAAACCAGA 
GTCAACCCCC ATTCTCTGCC TGACCCTGAA GTGAATGAGC AGTCTTCCTC CAAAGGGATG 
TTTAGAAAAA AGGGAGGATG GAAAGCAGGT CCCGAGGGCA CGTCTCAGGA GATCCCCAAG 
TATATAACTG CTTCTACTTT TGCTCAAGCA CGAGCTGCTG AAATCAGTGC TATGTTAAAA 
GCTGTGACCC AGAAGTCTTC GAATTCACTG GTTTTTCAGA CTCTGCCACG GCACATGCGA 
CGAAGAGCCA TGAGCCACAA CGTCAAACGC CTTCCCAGAC GGTTACAGGA GATTGCCCAG 
AAAGAGGCGG AGAAAGCCGT ACATCAGAAA AAAGAACATT CAAAAAATAA ATGCCATAAA 
GCTCGAAGAT GTCACATGAA CCGGACGCTA GAATTTAACC GTAGACAAAA GAAGAACATT 
TGGTTAGAAA CTCACATCTG GCACGCCAAG CGGTTTCATA TGGTCAAGAA GTGGGGCTAC 
TGCCTTGGGG AGAGGCCAAC AGTCAAGAGC CACAGAGCCT GCTATCGAGC CATGACGAAC 
CGGTGCCTCC TGCAGGATTT ATCCTATTAC TGTTGTTTGG AGTTGAAAGG CAAAGAGGAA 
GAAATACTAA AGGCGCTTTC TGGAATGTGT AACATAGACA CAGGGCTGAC GTTTGCAGCA 
GTTCACTGCT TGTCTGGAAA GCGCCAAGGG AGCCTTGTGC TTTATCGGGT GAATAAATAT 
CCCAGAGAAA TGCTTGGGCC TGTTACGTTT ATCTGGAAGT CCCAGAGGAC CCCGGGTGAC 
CCTTCTGAGA GCAGGCAGCT GTGGATCTGG CTGCATCCAA CCCTTAAACA GGATATCTTA 
GAGGAAATAA AAGCAGCGTG CCAGTGTGTG GAACCCATCA AATCAGCTGT CTGCATCGCT 
GACCCACTTC CAACACCATC CCAAGAAAAA AGCCAAACTG AATTGCCTGA CGAGAAAATT 
GGCAAGAAAA GAAAAAGGAA AGATGATGGA GAAAATGCTA AACCAATTAA AAAAATTATC 
GGTGATGGAA CTAGAGATCC ATGTCTACCA TACTCTTGGA TCTCTCCAAC CACAGGCATT 
ATAATCAGCG ATTTGACGAT GGAGATGAAC AGATTCCGGC TGATTGGGCC ACTTTCCCAC 
TCCATCCTAA CTGAAGCAAT AAAAGCTGCT TCTGTCCACA CTGTGGGAGA GGACACAGAG 
GAGACACCTC ACCGCTGGTG GATAGAAACC TGTAAGAAAC CTGACAGCGT TTCCCTTCAT 
TGCAGACAAG AAGCCATTTT CGAGTTGTTG GGAGGAATAA CATCACCAGC AGAAATTCCG 
GCAGGTACTA TTCTGGGACT GACAGTTGGG GATCCTCGAA TAAATTTGCC CCAAAAGAAG 
TCCAAAGCTT TGCCCAATCC AGAAAAATGC CAAGATAATG AGAAAGTTAG ACAGCTGCTT 
CTGGAGGGTG TGCCTGTGGA ATGTACGCAT AGCTTTATCT GGAACCAAGA TATCTGTAAG 
AGTGTCACAG AGAATAAAAT CTCGGATCAG GATTTAAACC GGATGAGGAG TGAATTGCTG 
GTGCCTGGGT CACAGCTTAT TTTAGGTCCC CATGAATCCA AGATACCTAT ACTTTTGATT 
CAGCAGCCAG GAAAAGTGAC TGGTGAAGAT CGACTAGGCT GGGGAAGTGG CTGGGATGTC 
CTACTCCCAA AGGGCTGGGG CATGGCTTTC TGGATTCCAT TTATTTATCG AGGTGTGAGA 
GTCGGAGGGT TGAAAGAGTC TGCAGTGCAT TCTCAGTATA AGAGGTCGCC TAATGTCCCA 
GGCGATTTTC CAGACTGCCC TGCCGGGATG CTGTTTGCGG AAGAGCAAGC TAAGAATCTT 
CTTGAAAAGT ACAAAAGACG CCCTCCTGCA AAACGGCCCA ACTACGTTAA GCTTGGCACT 
CTGGCACCTT TCTGCTGTCC CTGGGAGCAG TTAACTCAAG ACTGGGAGTC AAGAGTCCAG 
GCTTACGAAG AACCTTCTGT AGCTTCATCT CCAAATGGTA AGGAGAGTGA CCTAAGAAGA 
TCTGAGGTGC CTTGTGCTCC CATGCCTAAA AAAACTCATC AGCCATCTGA TGAAGTGGGC 
ACATCCATAG AGCACCCCAG GGAGGCAGAG GAGGTAATGG ATGCAGGGTG TCAAGAATCG 
GCAGGGCCTG AGAGGATCAC AGACCAGGAG GCCAGTGAAA ACCATGTTGC TGCCACAGGG 
AGTCACCTCT GCGTTCTCAG GAGTAGAAAA TTACTGAAGC AACTGTCAGC CTGGTGTGGG 
CCCAGTTCTG AGGATAGTCG GGGAGGCCGG CGAGCTCCCG GCAGAGGCCA GCAAGGATTG 
ACCAGAGAGG CTTGCCTGTC CATCTTGGGC CACTTCCCCA GGGCCCTGGT TTGGGTCAGC 
CTGTCCCTGC TCAGCAAGGG CAGCCCCGAG CCTCACACCA TGATCTGTGT CCCAGCCAAG 
GAGGACTTCC TCCAGCTCCA TGAGGACTGG CATTACTGTG GGCCCCAGGA ATCCAAACAC 
AGTGACCCAT TCAGGAGCAA GATCCTGAAA CAGAAAGAGA AGAAGAAAAG GGAGAAGAGG 
CAGAAGCCAG GACGTGCCTC TTCTGATGGC CCGGCGGGGG AAGAGCCCGT GGCTGGGCAG 
GAAGCTCTGA CTCTAGGGCT GTGGTCAGGC CCTCTGCCGC GTGTGACGTT GCACTGCTCC 
AGAACTCTCC TAGGCTTTGT GACTCAGGGA GATTTTTCCA TGGCTGTTGG CTGTGGAGAA 
GCCCTGGGGT TTGTTAGCTT GACAGGCTTG CTGGATATGC TGTCCAGCCA GCCTGCAGCG 
CAGAGGGGCT TAGTGCTACT GAGGCCTCCC GCCTCTCTGC AGTATCGATT TGCGAGGATT 
GCTATTGAGG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Broadening the phenotypic spectrum of POP1-skeletal dysplasias: identification of POP1 mutations in a mild and severe skeletal dysplasia.
Clinical genetics92(1)91-98(2017 Jul)
Barraza-Garc?a J,Rivera-Pedroza CI,Hisado-Oliva A,Belinch?n-Mart?nez A,Sentchordi-Montan? L,Duncan EL,Clark GR,Del Pozo A,Ib??ez-Garikano K,Offiah A,Prieto-Matos P,Cormier-Daire V,Heath KE

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Further evidence of POP1 mutations as the cause of anauxetic dysplasia.
American journal of medical genetics. Part A170(9)2462-5(2016 Sep)
Elalaoui SC,Laarabi FZ,Mansouri M,Mrani NA,Nishimura G,Sefiani A

The PYRIN Domain-only Protein POP1 Inhibits Inflammasome Assembly and Ameliorates Inflammatory Disease.
Immunity43(2)264-76(2015 Aug)
de Almeida L,Khare S,Misharin AV,Patel R,Ratsimandresy RA,Wallin MC,Perlman H,Greaves DR,Hoffman HM,Dorfleutner A,Stehlik C

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POP1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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