FRS3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FRS3
Entrez Gene ID	10817
Full Name	fibroblast growth factor receptor substrate 3
Synonyms	FRS2-beta,FRS2B,FRS2beta,SNT-2,SNT2
General protein information	Preferred Names fibroblast growth factor receptor substrate 3 Names fibroblast growth factor receptor substrate 3 FGFR substrate 3 FGFR-signaling adaptor SNT2 suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor) testicular tissue protein Li 71
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p21.1
Summary	This gene encodes a substrate for the fibroblast growth factor receptor. The encoded protein is found in the peripheral plasma membrane and links fibroblast growth factor receptor stimulation to activators of Ras. The encoded protein down-regulates extracellular regulated kinase 2 through direct binding. [provided by RefSeq, Jul 2013].
Disorder MIM:	607744

mRNA and Protein(s)

mRNA	Protein	Name
XM_011514254.2	XP_011512556.1	fibroblast growth factor receptor substrate 3 isoform X1
NM_006653.5	NP_006644.1	fibroblast growth factor receptor substrate 3
XM_011514255.2	XP_011512557.1	fibroblast growth factor receptor substrate 3 isoform X1
XM_011514254.1	XP_011512556.1	fibroblast growth factor receptor substrate 3 isoform X1
XM_017010193.1	XP_016865682.1	fibroblast growth factor receptor substrate 3 isoform X2
XM_011514255.1	XP_011512557.1	fibroblast growth factor receptor substrate 3 isoform X1
NM_006653.4	NP_006644.1	fibroblast growth factor receptor substrate 3

Pathways from BioSystems

Homologies

Homo sapiens (human)	FRS3	NP_006644.1
Pan troglodytes (chimpanzee)	FRS3	XP_527384.2
Xenopus tropicalis (tropical clawed frog)	frs3	NP_001107141.1
Bos taurus (cattle)	FRS3	NP_001092388.1
Rattus norvegicus (Norway rat)	Frs3	NP_001017382.1
Gallus gallus (chicken)	FRS3	XP_418044.4
	FRS3	XP_001084538.2
Danio rerio (zebrafish)	LOC100330147	XP_002662545.2
Canis lupus familiaris (dog)	FRS3	XP_538915.1
Mus musculus (house mouse)	Frs3	NP_659188.1

Gene Ontology
Bibliography

Related articles in PubMed

Phospho-tyrosine dependent protein-protein interaction network.
Grossmann A, Benlasfer N, Birth P, Hegele A, Wachsmuth F, Apelt L, Stelzl U
Molecular systems biology11(3)794(2015 Mar)

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
Perry JR, Day F, Elks CE, Sulem P, Thompson DJ, Ferreira T, He C, Chasman DI, Esko T, Thorleifsson G, Albrecht E, Ang WQ, Corre T, Cousminer DL, Feenstra B, Franceschini N, Ganna A, Johnson AD, Kjellqvist S, Lunetta KL, McMahon G, Nolte IM, Paternoster L, Porcu E, Smith AV, Stolk L, Teumer A, T?ernikova N, Tikkanen E, Ulivi S, Wagner EK, Amin N, Bierut LJ, Byrne EM, Hottenga JJ, Koller DL, Mangino M, Pers TH, Yerges-Armstrong LM, Zhao JH, Andrulis IL, Anton-Culver H, Atsma F, Bandinelli S, Beckmann MW, Benitez J, Blomqvist C, Bojesen SE, Bolla MK, Bonanni B, Brauch H, Brenner H, Buring JE, Chang-Claude J, Chanock S, Chen J, Chenevix-Trench G, Coll?e JM, Couch FJ, Couper D, Coveillo AD, Cox A, Czene K, D'adamo AP, Smith GD, De Vivo I, Demerath EW, Dennis J, Devilee P, Dieffenbach AK, Dunning AM, Eiriksdottir G, Eriksson JG, Fasching PA, Ferrucci L, Flesch-Janys D, Flyger H, Foroud T, Franke L, Garcia ME, Garc?a-Closas M, Geller F, de Geus EE, Giles GG, Gudbjartsson DF, Gudnason V, Gu?nel P, Guo S, Hall P, Hamann U, Haring R, Hartman CA, Heath AC, Hofman A, Hooning MJ, Hopper JL, Hu FB, Hunter DJ, Karasik D, Kiel DP, Knight JA, Kosma VM, Kutalik Z, Lai S, Lambrechts D, Lindblom A, M?gi R, Magnusson PK, Mannermaa A, Martin NG, Masson G, McArdle PF, McArdle WL, Melbye M, Michailidou K, Mihailov E, Milani L, Milne RL, Nevanlinna H, Neven P, Nohr EA, Oldehinkel AJ, Oostra BA, Palotie A, Peacock M, Pedersen NL, Peterlongo P, Peto J, Pharoah PD, Postma DS, Pouta A, Pylk?s K, Radice P, Ring S, Rivadeneira F, Robino A, Rose LM, Rudolph A, Salomaa V, Sanna S, Schlessinger D, Schmidt MK, Southey MC, Sovio U, Stampfer MJ, St?ckl D, Storniolo AM, Timpson NJ, Tyrer J, Visser JA, Vollenweider P, V?lzke H, Waeber G, Waldenberger M, Wallaschofski H, Wang Q, Willemsen G, Winqvist R, Wolffenbuttel BH, Wright MJ, , , , , , , Boomsma DI, Econs MJ, Khaw KT, Loos RJ, McCarthy MI, Montgomery GW, Rice JP, Streeten EA, Thorsteinsdottir U, van Duijn CM, Alizadeh BZ, Bergmann S, Boerwinkle E, Boyd HA, Crisponi L, Gasparini P, Gieger C, Harris TB, Ingelsson E, J?rvelin MR, Kraft P, Lawlor D, Metspalu A, Pennell CE, Ridker PM, Snieder H, S?rensen TI, Spector TD, Strachan DP, Uitterlinden AG, Wareham NJ, Widen E, Zygmunt M, Murray A, Easton DF, Stefansson K, Murabito JM, Ong KK
Nature514(7520)92-97(2014 Oct)

Adaptor protein complex of FRS2? and CIN85/CD2AP provides a novel mechanism for ErbB2/HER2 protein downregulation.
Minegishi Y, Shibagaki Y, Mizutani A, Fujita K, Tezuka T, Kinoshita M, Kuroda M, Hattori S, Gotoh N
Cancer science104(3)345-52(2013 Mar)

FRS2beta, a potential prognostic gene for non-small cell lung cancer, encodes a feedback inhibitor of EGF receptor family members by ERK binding.
Iejima D, Minegishi Y, Takenaka K, Siswanto A, Watanabe M, Huang L, Watanabe T, Tanaka F, Kuroda M, Gotoh N
Oncogene29(21)3087-99(2010 May)

Hepatitis C virus infection protein network.
de Chassey B, Navratil V, Tafforeau L, Hiet MS, Aublin-Gex A, Agaugu? S, Meiffren G, Pradezynski F, Faria BF, Chantier T, Le Breton M, Pellet J, Davoust N, Mangeot PE, Chaboud A, Penin F, Jacob Y, Vidalain PO, Vidal M, Andr? P, Rabourdin-Combe C, Lotteau V
Molecular systems biology4230(2008)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

an FRS2beta-CIN85/CD2AP-Cbl axis for downregulation of ErbB2 may regulate ErbB2 protein levels in physiological and pathological settings
Title: Adaptor protein complex of FRS2? and CIN85/CD2AP provides a novel mechanism for ErbB2/HER2 protein downregulation.

Mechanisms by which FRS2beta acts as a feedback inhibitor of EGFR family members and suggest a role for FRS2beta as a tumor suppressor.
Title: FRS2beta, a potential prognostic gene for non-small cell lung cancer, encodes a feedback inhibitor of EGF receptor family members by ERK binding.

Observational study of gene-disease association. (HuGE Navigator)
Title: Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease.

Novel mechanism of negative control of EGFR tyrosine kinase activity with SNT-2 by recruiting ERK2.
Title: Unique role of SNT-2/FRS2beta/FRS3 docking/adaptor protein for negative regulation in EGF receptor tyrosine kinase signaling pathways.

SNT-2 negatively regulates ERK2 signaling activated via EGF stimulation through direct binding to ERK2
Title: SNT-2 interacts with ERK2 and negatively regulates ERK2 signaling in response to EGF stimulation.

The following FRS3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FRS3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu14211	NM_006653.5 Latest version!	Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu14211	XM_011514254.2 Latest version!	Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu14211	XM_011514255.2 Latest version!	Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu96265	XM_017010193.1 Latest version!	Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu14211	XM_011514254.1	Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu14211	XM_011514255.1	Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu14211	NM_006653.4	Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FRS3 ( NM_006653.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_006644.1 Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), mRNA.

Price & Availability↑

CloneID	OHu14211
Clone ID Related Accession (Same CDS sequence)	XM_011514254.2 , NM_006653.5 , XM_011514255.2 , XM_011514254.1 , XM_011514255.1 , NM_006653.4
Accession Version	NM_006653.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Homo sapiens(human)
Product	fibroblast growth factor receptor substrate 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY036161.1 and AF036718.1. On Nov 22, 2018 this sequence version replaced NM_006653.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.307638.1, SRR1803615.490577.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000373018.7/ ENSP00000362109.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGAGCT GCTGCAGCTG CCTGAACAGA GACAGCGTTC CAGACAACCA CCCCACCAAG 
TTCAAGGTGA CAAATGTGGA TGATGAGGGG GTGGAGCTGG GCTCTGGGGT GATGGAGCTG 
ACGCAGAGTG AGCTGGTGCT GCACCTGCAT CGGCGTGAGG CCGTCCGCTG GCCTTATCTC 
TGCTTGCGGC GCTATGGCTA CGACTCCAAC CTCTTCTCCT TTGAGAGTGG CCGCCGATGT 
CAGACAGGCC AGGGAATATT TGCATTTAAG TGTTCCCGGG CTGAGGAAAT CTTCAACCTC 
CTTCAGGATC TGATGCAGTG CAACAGCATC AATGTGATGG AAGAGCCTGT CATCATCACC 
CGCAATAGCC ACCCCGCTGA GCTTGACCTC CCTCGAGCCC CCCAGCCACC CAATGCTCTA 
GGCTACACTG TCTCCAGCTT TTCCAATGGC TGCCCTGGAG AGGGCCCACG ATTCTCAGCT 
CCCCGGCGGC TCTCGACAAG CAGCCTGCGG CACCCCTCGC TTGGGGAAGA GTCCACCCAT 
GCCCTCATTG CTCCTGATGA GCAGTCCCAC ACCTATGTCA ACACACCGGC CAGTGAAGAT 
GACCACCGCA GGGGCCGCCA CTGCCTGCAG CCCCTGCCTG AGGGTCAGGC ACCCTTCCTC 
CCGCAGGCCC GGGGACCTGA CCAACGGGAC CCACAGGTGT TCTTGCAGCC AGGCCAGGTG 
AAGTTTGTGT TGGGCCCGAC CCCTGCTCGG CGGCACATGG TGAAGTGCCA GGGCCTCTGT 
CCCAGCCTGC ATGACCCCCC ACACCACAAT AATAACAATG AGGCCCCTTC TGAGTGTCCA 
GCCCAGCCCA AGTGCACCTA CGAGAACGTC ACCGGGGGGC TGTGGCGAGG GGCTGGCTGG 
AGACTGAGCC CAGAGGAGCC GGGCTGGAAT GGCCTTGCCC ACCGCCGGGC CGCCCTGCTG 
CACTATGAGA ACCTGCCCCC ACTGCCCCCT GTGTGGGAAA GCCAAGCCCA GCAGCTGGGA 
GGGGAGGCTG GGGATGATGG GGACTCGAGG GATGGGCTCA CACCCTCTTC CAATGGCTTC 
CCTGATGGTG AGGAGGACGA GACCCCACTG CAGAAGCCCA CCAGCACCCG GGCCGCCATC 
CGCAGCCACG GCAGCTTTCC TGTGCCACTG ACCCGCCGCC GCGGCTCCCC AAGGGTCTTC 
AACTTTGATT TCCGCCGGCC GGGGCCCGAG CCCCCAAGGC AGCTTAACTA CATCCAGGTG 
GAGCTAAAGG GCTGGGGTGG AGACCGCCCT AAGGGGCCCC AGAACCCCTC GAGCCCCCAA 
GCCCCCATGC CCACCACCCA CCCTGCCCGA AGCTCAGACT CCTACGCCGT GATTGACCTC 
AAAAAGACCG TGGCCATGTC CAACCTGCAG AGAGCTCTGC CCCGAGACGA TGGCACCGCC 
AGGAAAACCC GGCACAACAG CACCGACCTG CCTCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006644.1
CDS	253..1731
Translation	MGSCCSCLNRDSVPDNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHRREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPVIITRNSHPAELDLPRAPQPPNALGYTVSSFSNGCPGEGPRFSAPRRLSTSSLRHPSLGEESTHALIAPDEQSHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGPDQRDPQVFLQPGQVKFVLGPTPARRHMVKCQGLCPSLHDPPHHNNNNEAPSECPAQPKCTYENVTGGLWRGAGWRLSPEEPGWNGLAHRRAALLHYENLPPLPPVWESQAQQLGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTSTRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPGPEPPRQLNYIQVELKGWGGDRPKGPQNPSSPQAPMPTTHPARSSDSYAVIDLKKTVAMSNLQRALPRDDGTARKTRHNSTDLPL

Target ORF information:

RefSeq Version	NM_006653.5
Organism	Homo sapiens(human)
Definition	Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006653.5

ORF Insert Sequence:

ATGGGGAGCT GCTGCAGCTG CCTGAACAGA GACAGCGTTC CAGACAACCA CCCCACCAAG 
TTCAAGGTGA CAAATGTGGA TGATGAGGGG GTGGAGCTGG GCTCTGGGGT GATGGAGCTG 
ACGCAGAGTG AGCTGGTGCT GCACCTGCAT CGGCGTGAGG CCGTCCGCTG GCCTTATCTC 
TGCTTGCGGC GCTATGGCTA CGACTCCAAC CTCTTCTCCT TTGAGAGTGG CCGCCGATGT 
CAGACAGGCC AGGGAATATT TGCATTTAAG TGTTCCCGGG CTGAGGAAAT CTTCAACCTC 
CTTCAGGATC TGATGCAGTG CAACAGCATC AATGTGATGG AAGAGCCTGT CATCATCACC 
CGCAATAGCC ACCCCGCTGA GCTTGACCTC CCTCGAGCCC CCCAGCCACC CAATGCTCTA 
GGCTACACTG TCTCCAGCTT TTCCAATGGC TGCCCTGGAG AGGGCCCACG ATTCTCAGCT 
CCCCGGCGGC TCTCGACAAG CAGCCTGCGG CACCCCTCGC TTGGGGAAGA GTCCACCCAT 
GCCCTCATTG CTCCTGATGA GCAGTCCCAC ACCTATGTCA ACACACCGGC CAGTGAAGAT 
GACCACCGCA GGGGCCGCCA CTGCCTGCAG CCCCTGCCTG AGGGTCAGGC ACCCTTCCTC 
CCGCAGGCCC GGGGACCTGA CCAACGGGAC CCACAGGTGT TCTTGCAGCC AGGCCAGGTG 
AAGTTTGTGT TGGGCCCGAC CCCTGCTCGG CGGCACATGG TGAAGTGCCA GGGCCTCTGT 
CCCAGCCTGC ATGACCCCCC ACACCACAAT AATAACAATG AGGCCCCTTC TGAGTGTCCA 
GCCCAGCCCA AGTGCACCTA CGAGAACGTC ACCGGGGGGC TGTGGCGAGG GGCTGGCTGG 
AGACTGAGCC CAGAGGAGCC GGGCTGGAAT GGCCTTGCCC ACCGCCGGGC CGCCCTGCTG 
CACTATGAGA ACCTGCCCCC ACTGCCCCCT GTGTGGGAAA GCCAAGCCCA GCAGCTGGGA 
GGGGAGGCTG GGGATGATGG GGACTCGAGG GATGGGCTCA CACCCTCTTC CAATGGCTTC 
CCTGATGGTG AGGAGGACGA GACCCCACTG CAGAAGCCCA CCAGCACCCG GGCCGCCATC 
CGCAGCCACG GCAGCTTTCC TGTGCCACTG ACCCGCCGCC GCGGCTCCCC AAGGGTCTTC 
AACTTTGATT TCCGCCGGCC GGGGCCCGAG CCCCCAAGGC AGCTTAACTA CATCCAGGTG 
GAGCTAAAGG GCTGGGGTGG AGACCGCCCT AAGGGGCCCC AGAACCCCTC GAGCCCCCAA 
GCCCCCATGC CCACCACCCA CCCTGCCCGA AGCTCAGACT CCTACGCCGT GATTGACCTC 
AAAAAGACCG TGGCCATGTC CAACCTGCAG AGAGCTCTGC CCCGAGACGA TGGCACCGCC 
AGGAAAACCC GGCACAACAG CACCGACCTG CCTCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FRS3 ( NM_006653.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006644.1 Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), mRNA.

Price & Availability↑

CloneID	OHu14211
Clone ID Related Accession (Same CDS sequence)	XM_011514254.2 , NM_006653.5 , XM_011514255.2 , XM_011514254.1 , XM_011514255.1 , NM_006653.4
Accession Version	NM_006653.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	fibroblast growth factor receptor substrate 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY036161.1 and AF036718.1. On Jul 11, 2013 this sequence version replaced NM_006653.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.307638.1, SRR1803615.490577.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGAGCT GCTGCAGCTG CCTGAACAGA GACAGCGTTC CAGACAACCA CCCCACCAAG 
TTCAAGGTGA CAAATGTGGA TGATGAGGGG GTGGAGCTGG GCTCTGGGGT GATGGAGCTG 
ACGCAGAGTG AGCTGGTGCT GCACCTGCAT CGGCGTGAGG CCGTCCGCTG GCCTTATCTC 
TGCTTGCGGC GCTATGGCTA CGACTCCAAC CTCTTCTCCT TTGAGAGTGG CCGCCGATGT 
CAGACAGGCC AGGGAATATT TGCATTTAAG TGTTCCCGGG CTGAGGAAAT CTTCAACCTC 
CTTCAGGATC TGATGCAGTG CAACAGCATC AATGTGATGG AAGAGCCTGT CATCATCACC 
CGCAATAGCC ACCCCGCTGA GCTTGACCTC CCTCGAGCCC CCCAGCCACC CAATGCTCTA 
GGCTACACTG TCTCCAGCTT TTCCAATGGC TGCCCTGGAG AGGGCCCACG ATTCTCAGCT 
CCCCGGCGGC TCTCGACAAG CAGCCTGCGG CACCCCTCGC TTGGGGAAGA GTCCACCCAT 
GCCCTCATTG CTCCTGATGA GCAGTCCCAC ACCTATGTCA ACACACCGGC CAGTGAAGAT 
GACCACCGCA GGGGCCGCCA CTGCCTGCAG CCCCTGCCTG AGGGTCAGGC ACCCTTCCTC 
CCGCAGGCCC GGGGACCTGA CCAACGGGAC CCACAGGTGT TCTTGCAGCC AGGCCAGGTG 
AAGTTTGTGT TGGGCCCGAC CCCTGCTCGG CGGCACATGG TGAAGTGCCA GGGCCTCTGT 
CCCAGCCTGC ATGACCCCCC ACACCACAAT AATAACAATG AGGCCCCTTC TGAGTGTCCA 
GCCCAGCCCA AGTGCACCTA CGAGAACGTC ACCGGGGGGC TGTGGCGAGG GGCTGGCTGG 
AGACTGAGCC CAGAGGAGCC GGGCTGGAAT GGCCTTGCCC ACCGCCGGGC CGCCCTGCTG 
CACTATGAGA ACCTGCCCCC ACTGCCCCCT GTGTGGGAAA GCCAAGCCCA GCAGCTGGGA 
GGGGAGGCTG GGGATGATGG GGACTCGAGG GATGGGCTCA CACCCTCTTC CAATGGCTTC 
CCTGATGGTG AGGAGGACGA GACCCCACTG CAGAAGCCCA CCAGCACCCG GGCCGCCATC 
CGCAGCCACG GCAGCTTTCC TGTGCCACTG ACCCGCCGCC GCGGCTCCCC AAGGGTCTTC 
AACTTTGATT TCCGCCGGCC GGGGCCCGAG CCCCCAAGGC AGCTTAACTA CATCCAGGTG 
GAGCTAAAGG GCTGGGGTGG AGACCGCCCT AAGGGGCCCC AGAACCCCTC GAGCCCCCAA 
GCCCCCATGC CCACCACCCA CCCTGCCCGA AGCTCAGACT CCTACGCCGT GATTGACCTC 
AAAAAGACCG TGGCCATGTC CAACCTGCAG AGAGCTCTGC CCCGAGACGA TGGCACCGCC 
AGGAAAACCC GGCACAACAG CACCGACCTG CCTCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006644.1
CDS	258..1736
Translation	MGSCCSCLNRDSVPDNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHRREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPVIITRNSHPAELDLPRAPQPPNALGYTVSSFSNGCPGEGPRFSAPRRLSTSSLRHPSLGEESTHALIAPDEQSHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGPDQRDPQVFLQPGQVKFVLGPTPARRHMVKCQGLCPSLHDPPHHNNNNEAPSECPAQPKCTYENVTGGLWRGAGWRLSPEEPGWNGLAHRRAALLHYENLPPLPPVWESQAQQLGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTSTRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPGPEPPRQLNYIQVELKGWGGDRPKGPQNPSSPQAPMPTTHPARSSDSYAVIDLKKTVAMSNLQRALPRDDGTARKTRHNSTDLPL

Target ORF information:

RefSeq Version	NM_006653.4
Organism	Homo sapiens(human)
Definition	Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006653.4

ORF Insert Sequence:

ATGGGGAGCT GCTGCAGCTG CCTGAACAGA GACAGCGTTC CAGACAACCA CCCCACCAAG 
TTCAAGGTGA CAAATGTGGA TGATGAGGGG GTGGAGCTGG GCTCTGGGGT GATGGAGCTG 
ACGCAGAGTG AGCTGGTGCT GCACCTGCAT CGGCGTGAGG CCGTCCGCTG GCCTTATCTC 
TGCTTGCGGC GCTATGGCTA CGACTCCAAC CTCTTCTCCT TTGAGAGTGG CCGCCGATGT 
CAGACAGGCC AGGGAATATT TGCATTTAAG TGTTCCCGGG CTGAGGAAAT CTTCAACCTC 
CTTCAGGATC TGATGCAGTG CAACAGCATC AATGTGATGG AAGAGCCTGT CATCATCACC 
CGCAATAGCC ACCCCGCTGA GCTTGACCTC CCTCGAGCCC CCCAGCCACC CAATGCTCTA 
GGCTACACTG TCTCCAGCTT TTCCAATGGC TGCCCTGGAG AGGGCCCACG ATTCTCAGCT 
CCCCGGCGGC TCTCGACAAG CAGCCTGCGG CACCCCTCGC TTGGGGAAGA GTCCACCCAT 
GCCCTCATTG CTCCTGATGA GCAGTCCCAC ACCTATGTCA ACACACCGGC CAGTGAAGAT 
GACCACCGCA GGGGCCGCCA CTGCCTGCAG CCCCTGCCTG AGGGTCAGGC ACCCTTCCTC 
CCGCAGGCCC GGGGACCTGA CCAACGGGAC CCACAGGTGT TCTTGCAGCC AGGCCAGGTG 
AAGTTTGTGT TGGGCCCGAC CCCTGCTCGG CGGCACATGG TGAAGTGCCA GGGCCTCTGT 
CCCAGCCTGC ATGACCCCCC ACACCACAAT AATAACAATG AGGCCCCTTC TGAGTGTCCA 
GCCCAGCCCA AGTGCACCTA CGAGAACGTC ACCGGGGGGC TGTGGCGAGG GGCTGGCTGG 
AGACTGAGCC CAGAGGAGCC GGGCTGGAAT GGCCTTGCCC ACCGCCGGGC CGCCCTGCTG 
CACTATGAGA ACCTGCCCCC ACTGCCCCCT GTGTGGGAAA GCCAAGCCCA GCAGCTGGGA 
GGGGAGGCTG GGGATGATGG GGACTCGAGG GATGGGCTCA CACCCTCTTC CAATGGCTTC 
CCTGATGGTG AGGAGGACGA GACCCCACTG CAGAAGCCCA CCAGCACCCG GGCCGCCATC 
CGCAGCCACG GCAGCTTTCC TGTGCCACTG ACCCGCCGCC GCGGCTCCCC AAGGGTCTTC 
AACTTTGATT TCCGCCGGCC GGGGCCCGAG CCCCCAAGGC AGCTTAACTA CATCCAGGTG 
GAGCTAAAGG GCTGGGGTGG AGACCGCCCT AAGGGGCCCC AGAACCCCTC GAGCCCCCAA 
GCCCCCATGC CCACCACCCA CCCTGCCCGA AGCTCAGACT CCTACGCCGT GATTGACCTC 
AAAAAGACCG TGGCCATGTC CAACCTGCAG AGAGCTCTGC CCCGAGACGA TGGCACCGCC 
AGGAAAACCC GGCACAACAG CACCGACCTG CCTCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FRS3 ( XM_011514254.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512556.1 Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu14211
Clone ID Related Accession (Same CDS sequence)	XM_011514254.2 , NM_006653.5 , XM_011514255.2 , XM_011514254.1 , XM_011514255.1 , NM_006653.4
Accession Version	XM_011514254.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	fibroblast growth factor receptor substrate 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011514254.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAGCT GCTGCAGCTG CCTGAACAGA GACAGCGTTC CAGACAACCA CCCCACCAAG 
TTCAAGGTGA CAAATGTGGA TGATGAGGGG GTGGAGCTGG GCTCTGGGGT GATGGAGCTG 
ACGCAGAGTG AGCTGGTGCT GCACCTGCAT CGGCGTGAGG CCGTCCGCTG GCCTTATCTC 
TGCTTGCGGC GCTATGGCTA CGACTCCAAC CTCTTCTCCT TTGAGAGTGG CCGCCGATGT 
CAGACAGGCC AGGGAATATT TGCATTTAAG TGTTCCCGGG CTGAGGAAAT CTTCAACCTC 
CTTCAGGATC TGATGCAGTG CAACAGCATC AATGTGATGG AAGAGCCTGT CATCATCACC 
CGCAATAGCC ACCCCGCTGA GCTTGACCTC CCTCGAGCCC CCCAGCCACC CAATGCTCTA 
GGCTACACTG TCTCCAGCTT TTCCAATGGC TGCCCTGGAG AGGGCCCACG ATTCTCAGCT 
CCCCGGCGGC TCTCGACAAG CAGCCTGCGG CACCCCTCGC TTGGGGAAGA GTCCACCCAT 
GCCCTCATTG CTCCTGATGA GCAGTCCCAC ACCTATGTCA ACACACCGGC CAGTGAAGAT 
GACCACCGCA GGGGCCGCCA CTGCCTGCAG CCCCTGCCTG AGGGTCAGGC ACCCTTCCTC 
CCGCAGGCCC GGGGACCTGA CCAACGGGAC CCACAGGTGT TCTTGCAGCC AGGCCAGGTG 
AAGTTTGTGT TGGGCCCGAC CCCTGCTCGG CGGCACATGG TGAAGTGCCA GGGCCTCTGT 
CCCAGCCTGC ATGACCCCCC ACACCACAAT AATAACAATG AGGCCCCTTC TGAGTGTCCA 
GCCCAGCCCA AGTGCACCTA CGAGAACGTC ACCGGGGGGC TGTGGCGAGG GGCTGGCTGG 
AGACTGAGCC CAGAGGAGCC GGGCTGGAAT GGCCTTGCCC ACCGCCGGGC CGCCCTGCTG 
CACTATGAGA ACCTGCCCCC ACTGCCCCCT GTGTGGGAAA GCCAAGCCCA GCAGCTGGGA 
GGGGAGGCTG GGGATGATGG GGACTCGAGG GATGGGCTCA CACCCTCTTC CAATGGCTTC 
CCTGATGGTG AGGAGGACGA GACCCCACTG CAGAAGCCCA CCAGCACCCG GGCCGCCATC 
CGCAGCCACG GCAGCTTTCC TGTGCCACTG ACCCGCCGCC GCGGCTCCCC AAGGGTCTTC 
AACTTTGATT TCCGCCGGCC GGGGCCCGAG CCCCCAAGGC AGCTTAACTA CATCCAGGTG 
GAGCTAAAGG GCTGGGGTGG AGACCGCCCT AAGGGGCCCC AGAACCCCTC GAGCCCCCAA 
GCCCCCATGC CCACCACCCA CCCTGCCCGA AGCTCAGACT CCTACGCCGT GATTGACCTC 
AAAAAGACCG TGGCCATGTC CAACCTGCAG AGAGCTCTGC CCCGAGACGA TGGCACCGCC 
AGGAAAACCC GGCACAACAG CACCGACCTG CCTCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512556.1
CDS	1111..2589
Translation	MGSCCSCLNRDSVPDNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHRREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPVIITRNSHPAELDLPRAPQPPNALGYTVSSFSNGCPGEGPRFSAPRRLSTSSLRHPSLGEESTHALIAPDEQSHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGPDQRDPQVFLQPGQVKFVLGPTPARRHMVKCQGLCPSLHDPPHHNNNNEAPSECPAQPKCTYENVTGGLWRGAGWRLSPEEPGWNGLAHRRAALLHYENLPPLPPVWESQAQQLGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTSTRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPGPEPPRQLNYIQVELKGWGGDRPKGPQNPSSPQAPMPTTHPARSSDSYAVIDLKKTVAMSNLQRALPRDDGTARKTRHNSTDLPL

Target ORF information:

RefSeq Version	XM_011514254.2
Organism	Homo sapiens(human)
Definition	Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011514254.2

ORF Insert Sequence:

ATGGGGAGCT GCTGCAGCTG CCTGAACAGA GACAGCGTTC CAGACAACCA CCCCACCAAG 
TTCAAGGTGA CAAATGTGGA TGATGAGGGG GTGGAGCTGG GCTCTGGGGT GATGGAGCTG 
ACGCAGAGTG AGCTGGTGCT GCACCTGCAT CGGCGTGAGG CCGTCCGCTG GCCTTATCTC 
TGCTTGCGGC GCTATGGCTA CGACTCCAAC CTCTTCTCCT TTGAGAGTGG CCGCCGATGT 
CAGACAGGCC AGGGAATATT TGCATTTAAG TGTTCCCGGG CTGAGGAAAT CTTCAACCTC 
CTTCAGGATC TGATGCAGTG CAACAGCATC AATGTGATGG AAGAGCCTGT CATCATCACC 
CGCAATAGCC ACCCCGCTGA GCTTGACCTC CCTCGAGCCC CCCAGCCACC CAATGCTCTA 
GGCTACACTG TCTCCAGCTT TTCCAATGGC TGCCCTGGAG AGGGCCCACG ATTCTCAGCT 
CCCCGGCGGC TCTCGACAAG CAGCCTGCGG CACCCCTCGC TTGGGGAAGA GTCCACCCAT 
GCCCTCATTG CTCCTGATGA GCAGTCCCAC ACCTATGTCA ACACACCGGC CAGTGAAGAT 
GACCACCGCA GGGGCCGCCA CTGCCTGCAG CCCCTGCCTG AGGGTCAGGC ACCCTTCCTC 
CCGCAGGCCC GGGGACCTGA CCAACGGGAC CCACAGGTGT TCTTGCAGCC AGGCCAGGTG 
AAGTTTGTGT TGGGCCCGAC CCCTGCTCGG CGGCACATGG TGAAGTGCCA GGGCCTCTGT 
CCCAGCCTGC ATGACCCCCC ACACCACAAT AATAACAATG AGGCCCCTTC TGAGTGTCCA 
GCCCAGCCCA AGTGCACCTA CGAGAACGTC ACCGGGGGGC TGTGGCGAGG GGCTGGCTGG 
AGACTGAGCC CAGAGGAGCC GGGCTGGAAT GGCCTTGCCC ACCGCCGGGC CGCCCTGCTG 
CACTATGAGA ACCTGCCCCC ACTGCCCCCT GTGTGGGAAA GCCAAGCCCA GCAGCTGGGA 
GGGGAGGCTG GGGATGATGG GGACTCGAGG GATGGGCTCA CACCCTCTTC CAATGGCTTC 
CCTGATGGTG AGGAGGACGA GACCCCACTG CAGAAGCCCA CCAGCACCCG GGCCGCCATC 
CGCAGCCACG GCAGCTTTCC TGTGCCACTG ACCCGCCGCC GCGGCTCCCC AAGGGTCTTC 
AACTTTGATT TCCGCCGGCC GGGGCCCGAG CCCCCAAGGC AGCTTAACTA CATCCAGGTG 
GAGCTAAAGG GCTGGGGTGG AGACCGCCCT AAGGGGCCCC AGAACCCCTC GAGCCCCCAA 
GCCCCCATGC CCACCACCCA CCCTGCCCGA AGCTCAGACT CCTACGCCGT GATTGACCTC 
AAAAAGACCG TGGCCATGTC CAACCTGCAG AGAGCTCTGC CCCGAGACGA TGGCACCGCC 
AGGAAAACCC GGCACAACAG CACCGACCTG CCTCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FRS3 ( XM_011514255.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512557.1 Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu14211
Clone ID Related Accession (Same CDS sequence)	XM_011514254.2 , NM_006653.5 , XM_011514255.2 , XM_011514254.1 , XM_011514255.1 , NM_006653.4
Accession Version	XM_011514255.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	fibroblast growth factor receptor substrate 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011514255.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAGCT GCTGCAGCTG CCTGAACAGA GACAGCGTTC CAGACAACCA CCCCACCAAG 
TTCAAGGTGA CAAATGTGGA TGATGAGGGG GTGGAGCTGG GCTCTGGGGT GATGGAGCTG 
ACGCAGAGTG AGCTGGTGCT GCACCTGCAT CGGCGTGAGG CCGTCCGCTG GCCTTATCTC 
TGCTTGCGGC GCTATGGCTA CGACTCCAAC CTCTTCTCCT TTGAGAGTGG CCGCCGATGT 
CAGACAGGCC AGGGAATATT TGCATTTAAG TGTTCCCGGG CTGAGGAAAT CTTCAACCTC 
CTTCAGGATC TGATGCAGTG CAACAGCATC AATGTGATGG AAGAGCCTGT CATCATCACC 
CGCAATAGCC ACCCCGCTGA GCTTGACCTC CCTCGAGCCC CCCAGCCACC CAATGCTCTA 
GGCTACACTG TCTCCAGCTT TTCCAATGGC TGCCCTGGAG AGGGCCCACG ATTCTCAGCT 
CCCCGGCGGC TCTCGACAAG CAGCCTGCGG CACCCCTCGC TTGGGGAAGA GTCCACCCAT 
GCCCTCATTG CTCCTGATGA GCAGTCCCAC ACCTATGTCA ACACACCGGC CAGTGAAGAT 
GACCACCGCA GGGGCCGCCA CTGCCTGCAG CCCCTGCCTG AGGGTCAGGC ACCCTTCCTC 
CCGCAGGCCC GGGGACCTGA CCAACGGGAC CCACAGGTGT TCTTGCAGCC AGGCCAGGTG 
AAGTTTGTGT TGGGCCCGAC CCCTGCTCGG CGGCACATGG TGAAGTGCCA GGGCCTCTGT 
CCCAGCCTGC ATGACCCCCC ACACCACAAT AATAACAATG AGGCCCCTTC TGAGTGTCCA 
GCCCAGCCCA AGTGCACCTA CGAGAACGTC ACCGGGGGGC TGTGGCGAGG GGCTGGCTGG 
AGACTGAGCC CAGAGGAGCC GGGCTGGAAT GGCCTTGCCC ACCGCCGGGC CGCCCTGCTG 
CACTATGAGA ACCTGCCCCC ACTGCCCCCT GTGTGGGAAA GCCAAGCCCA GCAGCTGGGA 
GGGGAGGCTG GGGATGATGG GGACTCGAGG GATGGGCTCA CACCCTCTTC CAATGGCTTC 
CCTGATGGTG AGGAGGACGA GACCCCACTG CAGAAGCCCA CCAGCACCCG GGCCGCCATC 
CGCAGCCACG GCAGCTTTCC TGTGCCACTG ACCCGCCGCC GCGGCTCCCC AAGGGTCTTC 
AACTTTGATT TCCGCCGGCC GGGGCCCGAG CCCCCAAGGC AGCTTAACTA CATCCAGGTG 
GAGCTAAAGG GCTGGGGTGG AGACCGCCCT AAGGGGCCCC AGAACCCCTC GAGCCCCCAA 
GCCCCCATGC CCACCACCCA CCCTGCCCGA AGCTCAGACT CCTACGCCGT GATTGACCTC 
AAAAAGACCG TGGCCATGTC CAACCTGCAG AGAGCTCTGC CCCGAGACGA TGGCACCGCC 
AGGAAAACCC GGCACAACAG CACCGACCTG CCTCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512557.1
CDS	1106..2584
Translation	MGSCCSCLNRDSVPDNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHRREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPVIITRNSHPAELDLPRAPQPPNALGYTVSSFSNGCPGEGPRFSAPRRLSTSSLRHPSLGEESTHALIAPDEQSHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGPDQRDPQVFLQPGQVKFVLGPTPARRHMVKCQGLCPSLHDPPHHNNNNEAPSECPAQPKCTYENVTGGLWRGAGWRLSPEEPGWNGLAHRRAALLHYENLPPLPPVWESQAQQLGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTSTRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPGPEPPRQLNYIQVELKGWGGDRPKGPQNPSSPQAPMPTTHPARSSDSYAVIDLKKTVAMSNLQRALPRDDGTARKTRHNSTDLPL

Target ORF information:

RefSeq Version	XM_011514255.2
Organism	Homo sapiens(human)
Definition	Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011514255.2

ORF Insert Sequence:

ATGGGGAGCT GCTGCAGCTG CCTGAACAGA GACAGCGTTC CAGACAACCA CCCCACCAAG 
TTCAAGGTGA CAAATGTGGA TGATGAGGGG GTGGAGCTGG GCTCTGGGGT GATGGAGCTG 
ACGCAGAGTG AGCTGGTGCT GCACCTGCAT CGGCGTGAGG CCGTCCGCTG GCCTTATCTC 
TGCTTGCGGC GCTATGGCTA CGACTCCAAC CTCTTCTCCT TTGAGAGTGG CCGCCGATGT 
CAGACAGGCC AGGGAATATT TGCATTTAAG TGTTCCCGGG CTGAGGAAAT CTTCAACCTC 
CTTCAGGATC TGATGCAGTG CAACAGCATC AATGTGATGG AAGAGCCTGT CATCATCACC 
CGCAATAGCC ACCCCGCTGA GCTTGACCTC CCTCGAGCCC CCCAGCCACC CAATGCTCTA 
GGCTACACTG TCTCCAGCTT TTCCAATGGC TGCCCTGGAG AGGGCCCACG ATTCTCAGCT 
CCCCGGCGGC TCTCGACAAG CAGCCTGCGG CACCCCTCGC TTGGGGAAGA GTCCACCCAT 
GCCCTCATTG CTCCTGATGA GCAGTCCCAC ACCTATGTCA ACACACCGGC CAGTGAAGAT 
GACCACCGCA GGGGCCGCCA CTGCCTGCAG CCCCTGCCTG AGGGTCAGGC ACCCTTCCTC 
CCGCAGGCCC GGGGACCTGA CCAACGGGAC CCACAGGTGT TCTTGCAGCC AGGCCAGGTG 
AAGTTTGTGT TGGGCCCGAC CCCTGCTCGG CGGCACATGG TGAAGTGCCA GGGCCTCTGT 
CCCAGCCTGC ATGACCCCCC ACACCACAAT AATAACAATG AGGCCCCTTC TGAGTGTCCA 
GCCCAGCCCA AGTGCACCTA CGAGAACGTC ACCGGGGGGC TGTGGCGAGG GGCTGGCTGG 
AGACTGAGCC CAGAGGAGCC GGGCTGGAAT GGCCTTGCCC ACCGCCGGGC CGCCCTGCTG 
CACTATGAGA ACCTGCCCCC ACTGCCCCCT GTGTGGGAAA GCCAAGCCCA GCAGCTGGGA 
GGGGAGGCTG GGGATGATGG GGACTCGAGG GATGGGCTCA CACCCTCTTC CAATGGCTTC 
CCTGATGGTG AGGAGGACGA GACCCCACTG CAGAAGCCCA CCAGCACCCG GGCCGCCATC 
CGCAGCCACG GCAGCTTTCC TGTGCCACTG ACCCGCCGCC GCGGCTCCCC AAGGGTCTTC 
AACTTTGATT TCCGCCGGCC GGGGCCCGAG CCCCCAAGGC AGCTTAACTA CATCCAGGTG 
GAGCTAAAGG GCTGGGGTGG AGACCGCCCT AAGGGGCCCC AGAACCCCTC GAGCCCCCAA 
GCCCCCATGC CCACCACCCA CCCTGCCCGA AGCTCAGACT CCTACGCCGT GATTGACCTC 
AAAAAGACCG TGGCCATGTC CAACCTGCAG AGAGCTCTGC CCCGAGACGA TGGCACCGCC 
AGGAAAACCC GGCACAACAG CACCGACCTG CCTCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FRS3 ( XM_011514254.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512556.1 Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu14211
Clone ID Related Accession (Same CDS sequence)	XM_011514254.2 , NM_006653.5 , XM_011514255.2 , XM_011514254.1 , XM_011514255.1 , NM_006653.4
Accession Version	XM_011514254.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	fibroblast growth factor receptor substrate 3 isoform X1
Comment

ATGGGGAGCT GCTGCAGCTG CCTGAACAGA GACAGCGTTC CAGACAACCA CCCCACCAAG 
TTCAAGGTGA CAAATGTGGA TGATGAGGGG GTGGAGCTGG GCTCTGGGGT GATGGAGCTG 
ACGCAGAGTG AGCTGGTGCT GCACCTGCAT CGGCGTGAGG CCGTCCGCTG GCCTTATCTC 
TGCTTGCGGC GCTATGGCTA CGACTCCAAC CTCTTCTCCT TTGAGAGTGG CCGCCGATGT 
CAGACAGGCC AGGGAATATT TGCATTTAAG TGTTCCCGGG CTGAGGAAAT CTTCAACCTC 
CTTCAGGATC TGATGCAGTG CAACAGCATC AATGTGATGG AAGAGCCTGT CATCATCACC 
CGCAATAGCC ACCCCGCTGA GCTTGACCTC CCTCGAGCCC CCCAGCCACC CAATGCTCTA 
GGCTACACTG TCTCCAGCTT TTCCAATGGC TGCCCTGGAG AGGGCCCACG ATTCTCAGCT 
CCCCGGCGGC TCTCGACAAG CAGCCTGCGG CACCCCTCGC TTGGGGAAGA GTCCACCCAT 
GCCCTCATTG CTCCTGATGA GCAGTCCCAC ACCTATGTCA ACACACCGGC CAGTGAAGAT 
GACCACCGCA GGGGCCGCCA CTGCCTGCAG CCCCTGCCTG AGGGTCAGGC ACCCTTCCTC 
CCGCAGGCCC GGGGACCTGA CCAACGGGAC CCACAGGTGT TCTTGCAGCC AGGCCAGGTG 
AAGTTTGTGT TGGGCCCGAC CCCTGCTCGG CGGCACATGG TGAAGTGCCA GGGCCTCTGT 
CCCAGCCTGC ATGACCCCCC ACACCACAAT AATAACAATG AGGCCCCTTC TGAGTGTCCA 
GCCCAGCCCA AGTGCACCTA CGAGAACGTC ACCGGGGGGC TGTGGCGAGG GGCTGGCTGG 
AGACTGAGCC CAGAGGAGCC GGGCTGGAAT GGCCTTGCCC ACCGCCGGGC CGCCCTGCTG 
CACTATGAGA ACCTGCCCCC ACTGCCCCCT GTGTGGGAAA GCCAAGCCCA GCAGCTGGGA 
GGGGAGGCTG GGGATGATGG GGACTCGAGG GATGGGCTCA CACCCTCTTC CAATGGCTTC 
CCTGATGGTG AGGAGGACGA GACCCCACTG CAGAAGCCCA CCAGCACCCG GGCCGCCATC 
CGCAGCCACG GCAGCTTTCC TGTGCCACTG ACCCGCCGCC GCGGCTCCCC AAGGGTCTTC 
AACTTTGATT TCCGCCGGCC GGGGCCCGAG CCCCCAAGGC AGCTTAACTA CATCCAGGTG 
GAGCTAAAGG GCTGGGGTGG AGACCGCCCT AAGGGGCCCC AGAACCCCTC GAGCCCCCAA 
GCCCCCATGC CCACCACCCA CCCTGCCCGA AGCTCAGACT CCTACGCCGT GATTGACCTC 
AAAAAGACCG TGGCCATGTC CAACCTGCAG AGAGCTCTGC CCCGAGACGA TGGCACCGCC 
AGGAAAACCC GGCACAACAG CACCGACCTG CCTCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011512556.1

Translation

MGSCCSCLNRDSVPDNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHRREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPVIITRNSHPAELDLPRAPQPPNALGYTVSSFSNGCPGEGPRFSAPRRLSTSSLRHPSLGEESTHALIAPDEQSHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGPDQRDPQVFLQPGQVKFVLGPTPARRHMVKCQGLCPSLHDPPHHNNNNEAPSECPAQPKCTYENVTGGLWRGAGWRLSPEEPGWNGLAHRRAALLHYENLPPLPPVWESQAQQLGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTSTRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPGPEPPRQLNYIQVELKGWGGDRPKGPQNPSSPQAPMPTTHPARSSDSYAVIDLKKTVAMSNLQRALPRDDGTARKTRHNSTDLPL

Target ORF information:

RefSeq Version	XM_011514254.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011514254.1

ORF Insert Sequence:

ATGGGGAGCT GCTGCAGCTG CCTGAACAGA GACAGCGTTC CAGACAACCA CCCCACCAAG 
TTCAAGGTGA CAAATGTGGA TGATGAGGGG GTGGAGCTGG GCTCTGGGGT GATGGAGCTG 
ACGCAGAGTG AGCTGGTGCT GCACCTGCAT CGGCGTGAGG CCGTCCGCTG GCCTTATCTC 
TGCTTGCGGC GCTATGGCTA CGACTCCAAC CTCTTCTCCT TTGAGAGTGG CCGCCGATGT 
CAGACAGGCC AGGGAATATT TGCATTTAAG TGTTCCCGGG CTGAGGAAAT CTTCAACCTC 
CTTCAGGATC TGATGCAGTG CAACAGCATC AATGTGATGG AAGAGCCTGT CATCATCACC 
CGCAATAGCC ACCCCGCTGA GCTTGACCTC CCTCGAGCCC CCCAGCCACC CAATGCTCTA 
GGCTACACTG TCTCCAGCTT TTCCAATGGC TGCCCTGGAG AGGGCCCACG ATTCTCAGCT 
CCCCGGCGGC TCTCGACAAG CAGCCTGCGG CACCCCTCGC TTGGGGAAGA GTCCACCCAT 
GCCCTCATTG CTCCTGATGA GCAGTCCCAC ACCTATGTCA ACACACCGGC CAGTGAAGAT 
GACCACCGCA GGGGCCGCCA CTGCCTGCAG CCCCTGCCTG AGGGTCAGGC ACCCTTCCTC 
CCGCAGGCCC GGGGACCTGA CCAACGGGAC CCACAGGTGT TCTTGCAGCC AGGCCAGGTG 
AAGTTTGTGT TGGGCCCGAC CCCTGCTCGG CGGCACATGG TGAAGTGCCA GGGCCTCTGT 
CCCAGCCTGC ATGACCCCCC ACACCACAAT AATAACAATG AGGCCCCTTC TGAGTGTCCA 
GCCCAGCCCA AGTGCACCTA CGAGAACGTC ACCGGGGGGC TGTGGCGAGG GGCTGGCTGG 
AGACTGAGCC CAGAGGAGCC GGGCTGGAAT GGCCTTGCCC ACCGCCGGGC CGCCCTGCTG 
CACTATGAGA ACCTGCCCCC ACTGCCCCCT GTGTGGGAAA GCCAAGCCCA GCAGCTGGGA 
GGGGAGGCTG GGGATGATGG GGACTCGAGG GATGGGCTCA CACCCTCTTC CAATGGCTTC 
CCTGATGGTG AGGAGGACGA GACCCCACTG CAGAAGCCCA CCAGCACCCG GGCCGCCATC 
CGCAGCCACG GCAGCTTTCC TGTGCCACTG ACCCGCCGCC GCGGCTCCCC AAGGGTCTTC 
AACTTTGATT TCCGCCGGCC GGGGCCCGAG CCCCCAAGGC AGCTTAACTA CATCCAGGTG 
GAGCTAAAGG GCTGGGGTGG AGACCGCCCT AAGGGGCCCC AGAACCCCTC GAGCCCCCAA 
GCCCCCATGC CCACCACCCA CCCTGCCCGA AGCTCAGACT CCTACGCCGT GATTGACCTC 
AAAAAGACCG TGGCCATGTC CAACCTGCAG AGAGCTCTGC CCCGAGACGA TGGCACCGCC 
AGGAAAACCC GGCACAACAG CACCGACCTG CCTCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FRS3 ( XM_011514255.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512557.1 Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu14211
Clone ID Related Accession (Same CDS sequence)	XM_011514254.2 , NM_006653.5 , XM_011514255.2 , XM_011514254.1 , XM_011514255.1 , NM_006653.4
Accession Version	XM_011514255.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	fibroblast growth factor receptor substrate 3 isoform X1
Comment

ATGGGGAGCT GCTGCAGCTG CCTGAACAGA GACAGCGTTC CAGACAACCA CCCCACCAAG 
TTCAAGGTGA CAAATGTGGA TGATGAGGGG GTGGAGCTGG GCTCTGGGGT GATGGAGCTG 
ACGCAGAGTG AGCTGGTGCT GCACCTGCAT CGGCGTGAGG CCGTCCGCTG GCCTTATCTC 
TGCTTGCGGC GCTATGGCTA CGACTCCAAC CTCTTCTCCT TTGAGAGTGG CCGCCGATGT 
CAGACAGGCC AGGGAATATT TGCATTTAAG TGTTCCCGGG CTGAGGAAAT CTTCAACCTC 
CTTCAGGATC TGATGCAGTG CAACAGCATC AATGTGATGG AAGAGCCTGT CATCATCACC 
CGCAATAGCC ACCCCGCTGA GCTTGACCTC CCTCGAGCCC CCCAGCCACC CAATGCTCTA 
GGCTACACTG TCTCCAGCTT TTCCAATGGC TGCCCTGGAG AGGGCCCACG ATTCTCAGCT 
CCCCGGCGGC TCTCGACAAG CAGCCTGCGG CACCCCTCGC TTGGGGAAGA GTCCACCCAT 
GCCCTCATTG CTCCTGATGA GCAGTCCCAC ACCTATGTCA ACACACCGGC CAGTGAAGAT 
GACCACCGCA GGGGCCGCCA CTGCCTGCAG CCCCTGCCTG AGGGTCAGGC ACCCTTCCTC 
CCGCAGGCCC GGGGACCTGA CCAACGGGAC CCACAGGTGT TCTTGCAGCC AGGCCAGGTG 
AAGTTTGTGT TGGGCCCGAC CCCTGCTCGG CGGCACATGG TGAAGTGCCA GGGCCTCTGT 
CCCAGCCTGC ATGACCCCCC ACACCACAAT AATAACAATG AGGCCCCTTC TGAGTGTCCA 
GCCCAGCCCA AGTGCACCTA CGAGAACGTC ACCGGGGGGC TGTGGCGAGG GGCTGGCTGG 
AGACTGAGCC CAGAGGAGCC GGGCTGGAAT GGCCTTGCCC ACCGCCGGGC CGCCCTGCTG 
CACTATGAGA ACCTGCCCCC ACTGCCCCCT GTGTGGGAAA GCCAAGCCCA GCAGCTGGGA 
GGGGAGGCTG GGGATGATGG GGACTCGAGG GATGGGCTCA CACCCTCTTC CAATGGCTTC 
CCTGATGGTG AGGAGGACGA GACCCCACTG CAGAAGCCCA CCAGCACCCG GGCCGCCATC 
CGCAGCCACG GCAGCTTTCC TGTGCCACTG ACCCGCCGCC GCGGCTCCCC AAGGGTCTTC 
AACTTTGATT TCCGCCGGCC GGGGCCCGAG CCCCCAAGGC AGCTTAACTA CATCCAGGTG 
GAGCTAAAGG GCTGGGGTGG AGACCGCCCT AAGGGGCCCC AGAACCCCTC GAGCCCCCAA 
GCCCCCATGC CCACCACCCA CCCTGCCCGA AGCTCAGACT CCTACGCCGT GATTGACCTC 
AAAAAGACCG TGGCCATGTC CAACCTGCAG AGAGCTCTGC CCCGAGACGA TGGCACCGCC 
AGGAAAACCC GGCACAACAG CACCGACCTG CCTCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011512557.1

Translation

MGSCCSCLNRDSVPDNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHRREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPVIITRNSHPAELDLPRAPQPPNALGYTVSSFSNGCPGEGPRFSAPRRLSTSSLRHPSLGEESTHALIAPDEQSHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGPDQRDPQVFLQPGQVKFVLGPTPARRHMVKCQGLCPSLHDPPHHNNNNEAPSECPAQPKCTYENVTGGLWRGAGWRLSPEEPGWNGLAHRRAALLHYENLPPLPPVWESQAQQLGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTSTRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPGPEPPRQLNYIQVELKGWGGDRPKGPQNPSSPQAPMPTTHPARSSDSYAVIDLKKTVAMSNLQRALPRDDGTARKTRHNSTDLPL

Target ORF information:

RefSeq Version	XM_011514255.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011514255.1

ORF Insert Sequence:

ATGGGGAGCT GCTGCAGCTG CCTGAACAGA GACAGCGTTC CAGACAACCA CCCCACCAAG 
TTCAAGGTGA CAAATGTGGA TGATGAGGGG GTGGAGCTGG GCTCTGGGGT GATGGAGCTG 
ACGCAGAGTG AGCTGGTGCT GCACCTGCAT CGGCGTGAGG CCGTCCGCTG GCCTTATCTC 
TGCTTGCGGC GCTATGGCTA CGACTCCAAC CTCTTCTCCT TTGAGAGTGG CCGCCGATGT 
CAGACAGGCC AGGGAATATT TGCATTTAAG TGTTCCCGGG CTGAGGAAAT CTTCAACCTC 
CTTCAGGATC TGATGCAGTG CAACAGCATC AATGTGATGG AAGAGCCTGT CATCATCACC 
CGCAATAGCC ACCCCGCTGA GCTTGACCTC CCTCGAGCCC CCCAGCCACC CAATGCTCTA 
GGCTACACTG TCTCCAGCTT TTCCAATGGC TGCCCTGGAG AGGGCCCACG ATTCTCAGCT 
CCCCGGCGGC TCTCGACAAG CAGCCTGCGG CACCCCTCGC TTGGGGAAGA GTCCACCCAT 
GCCCTCATTG CTCCTGATGA GCAGTCCCAC ACCTATGTCA ACACACCGGC CAGTGAAGAT 
GACCACCGCA GGGGCCGCCA CTGCCTGCAG CCCCTGCCTG AGGGTCAGGC ACCCTTCCTC 
CCGCAGGCCC GGGGACCTGA CCAACGGGAC CCACAGGTGT TCTTGCAGCC AGGCCAGGTG 
AAGTTTGTGT TGGGCCCGAC CCCTGCTCGG CGGCACATGG TGAAGTGCCA GGGCCTCTGT 
CCCAGCCTGC ATGACCCCCC ACACCACAAT AATAACAATG AGGCCCCTTC TGAGTGTCCA 
GCCCAGCCCA AGTGCACCTA CGAGAACGTC ACCGGGGGGC TGTGGCGAGG GGCTGGCTGG 
AGACTGAGCC CAGAGGAGCC GGGCTGGAAT GGCCTTGCCC ACCGCCGGGC CGCCCTGCTG 
CACTATGAGA ACCTGCCCCC ACTGCCCCCT GTGTGGGAAA GCCAAGCCCA GCAGCTGGGA 
GGGGAGGCTG GGGATGATGG GGACTCGAGG GATGGGCTCA CACCCTCTTC CAATGGCTTC 
CCTGATGGTG AGGAGGACGA GACCCCACTG CAGAAGCCCA CCAGCACCCG GGCCGCCATC 
CGCAGCCACG GCAGCTTTCC TGTGCCACTG ACCCGCCGCC GCGGCTCCCC AAGGGTCTTC 
AACTTTGATT TCCGCCGGCC GGGGCCCGAG CCCCCAAGGC AGCTTAACTA CATCCAGGTG 
GAGCTAAAGG GCTGGGGTGG AGACCGCCCT AAGGGGCCCC AGAACCCCTC GAGCCCCCAA 
GCCCCCATGC CCACCACCCA CCCTGCCCGA AGCTCAGACT CCTACGCCGT GATTGACCTC 
AAAAAGACCG TGGCCATGTC CAACCTGCAG AGAGCTCTGC CCCGAGACGA TGGCACCGCC 
AGGAAAACCC GGCACAACAG CACCGACCTG CCTCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FRS3 ( XM_017010193.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016865682.1 Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu96265
Clone ID Related Accession (Same CDS sequence)	XM_017010193.1
Accession Version	XM_017010193.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1368bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	fibroblast growth factor receptor substrate 3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCTGA CGCAGAGTGA GCTGGTGCTG CACCTGCATC GGCGTGAGGC CGTCCGCTGG 
CCTTATCTCT GCTTGCGGCG CTATGGCTAC GACTCCAACC TCTTCTCCTT TGAGAGTGGC 
CGCCGATGTC AGACAGGCCA GGGAATATTT GCATTTAAGT GTTCCCGGGC TGAGGAAATC 
TTCAACCTCC TTCAGGATCT GATGCAGTGC AACAGCATCA ATGTGATGGA AGAGCCTGTC 
ATCATCACCC GCAATAGCCA CCCCGCTGAG CTTGACCTCC CTCGAGCCCC CCAGCCACCC 
AATGCTCTAG GCTACACTGT CTCCAGCTTT TCCAATGGCT GCCCTGGAGA GGGCCCACGA 
TTCTCAGCTC CCCGGCGGCT CTCGACAAGC AGCCTGCGGC ACCCCTCGCT TGGGGAAGAG 
TCCACCCATG CCCTCATTGC TCCTGATGAG CAGTCCCACA CCTATGTCAA CACACCGGCC 
AGTGAAGATG ACCACCGCAG GGGCCGCCAC TGCCTGCAGC CCCTGCCTGA GGGTCAGGCA 
CCCTTCCTCC CGCAGGCCCG GGGACCTGAC CAACGGGACC CACAGGTGTT CTTGCAGCCA 
GGCCAGGTGA AGTTTGTGTT GGGCCCGACC CCTGCTCGGC GGCACATGGT GAAGTGCCAG 
GGCCTCTGTC CCAGCCTGCA TGACCCCCCA CACCACAATA ATAACAATGA GGCCCCTTCT 
GAGTGTCCAG CCCAGCCCAA GTGCACCTAC GAGAACGTCA CCGGGGGGCT GTGGCGAGGG 
GCTGGCTGGA GACTGAGCCC AGAGGAGCCG GGCTGGAATG GCCTTGCCCA CCGCCGGGCC 
GCCCTGCTGC ACTATGAGAA CCTGCCCCCA CTGCCCCCTG TGTGGGAAAG CCAAGCCCAG 
CAGCTGGGAG GGGAGGCTGG GGATGATGGG GACTCGAGGG ATGGGCTCAC ACCCTCTTCC 
AATGGCTTCC CTGATGGTGA GGAGGACGAG ACCCCACTGC AGAAGCCCAC CAGCACCCGG 
GCCGCCATCC GCAGCCACGG CAGCTTTCCT GTGCCACTGA CCCGCCGCCG CGGCTCCCCA 
AGGGTCTTCA ACTTTGATTT CCGCCGGCCG GGGCCCGAGC CCCCAAGGCA GCTTAACTAC 
ATCCAGGTGG AGCTAAAGGG CTGGGGTGGA GACCGCCCTA AGGGGCCCCA GAACCCCTCG 
AGCCCCCAAG CCCCCATGCC CACCACCCAC CCTGCCCGAA GCTCAGACTC CTACGCCGTG 
ATTGACCTCA AAAAGACCGT GGCCATGTCC AACCTGCAGA GAGCTCTGCC CCGAGACGAT 
GGCACCGCCA GGAAAACCCG GCACAACAGC ACCGACCTGC CTCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016865682.1
CDS	1977..3344
Translation	MELTQSELVLHLHRREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPVIITRNSHPAELDLPRAPQPPNALGYTVSSFSNGCPGEGPRFSAPRRLSTSSLRHPSLGEESTHALIAPDEQSHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGPDQRDPQVFLQPGQVKFVLGPTPARRHMVKCQGLCPSLHDPPHHNNNNEAPSECPAQPKCTYENVTGGLWRGAGWRLSPEEPGWNGLAHRRAALLHYENLPPLPPVWESQAQQLGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTSTRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPGPEPPRQLNYIQVELKGWGGDRPKGPQNPSSPQAPMPTTHPARSSDSYAVIDLKKTVAMSNLQRALPRDDGTARKTRHNSTDLPL

Target ORF information:

RefSeq Version	XM_017010193.1
Organism	Homo sapiens(human)
Definition	Homo sapiens fibroblast growth factor receptor substrate 3 (FRS3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017010193.1

ORF Insert Sequence:

ATGGAGCTGA CGCAGAGTGA GCTGGTGCTG CACCTGCATC GGCGTGAGGC CGTCCGCTGG 
CCTTATCTCT GCTTGCGGCG CTATGGCTAC GACTCCAACC TCTTCTCCTT TGAGAGTGGC 
CGCCGATGTC AGACAGGCCA GGGAATATTT GCATTTAAGT GTTCCCGGGC TGAGGAAATC 
TTCAACCTCC TTCAGGATCT GATGCAGTGC AACAGCATCA ATGTGATGGA AGAGCCTGTC 
ATCATCACCC GCAATAGCCA CCCCGCTGAG CTTGACCTCC CTCGAGCCCC CCAGCCACCC 
AATGCTCTAG GCTACACTGT CTCCAGCTTT TCCAATGGCT GCCCTGGAGA GGGCCCACGA 
TTCTCAGCTC CCCGGCGGCT CTCGACAAGC AGCCTGCGGC ACCCCTCGCT TGGGGAAGAG 
TCCACCCATG CCCTCATTGC TCCTGATGAG CAGTCCCACA CCTATGTCAA CACACCGGCC 
AGTGAAGATG ACCACCGCAG GGGCCGCCAC TGCCTGCAGC CCCTGCCTGA GGGTCAGGCA 
CCCTTCCTCC CGCAGGCCCG GGGACCTGAC CAACGGGACC CACAGGTGTT CTTGCAGCCA 
GGCCAGGTGA AGTTTGTGTT GGGCCCGACC CCTGCTCGGC GGCACATGGT GAAGTGCCAG 
GGCCTCTGTC CCAGCCTGCA TGACCCCCCA CACCACAATA ATAACAATGA GGCCCCTTCT 
GAGTGTCCAG CCCAGCCCAA GTGCACCTAC GAGAACGTCA CCGGGGGGCT GTGGCGAGGG 
GCTGGCTGGA GACTGAGCCC AGAGGAGCCG GGCTGGAATG GCCTTGCCCA CCGCCGGGCC 
GCCCTGCTGC ACTATGAGAA CCTGCCCCCA CTGCCCCCTG TGTGGGAAAG CCAAGCCCAG 
CAGCTGGGAG GGGAGGCTGG GGATGATGGG GACTCGAGGG ATGGGCTCAC ACCCTCTTCC 
AATGGCTTCC CTGATGGTGA GGAGGACGAG ACCCCACTGC AGAAGCCCAC CAGCACCCGG 
GCCGCCATCC GCAGCCACGG CAGCTTTCCT GTGCCACTGA CCCGCCGCCG CGGCTCCCCA 
AGGGTCTTCA ACTTTGATTT CCGCCGGCCG GGGCCCGAGC CCCCAAGGCA GCTTAACTAC 
ATCCAGGTGG AGCTAAAGGG CTGGGGTGGA GACCGCCCTA AGGGGCCCCA GAACCCCTCG 
AGCCCCCAAG CCCCCATGCC CACCACCCAC CCTGCCCGAA GCTCAGACTC CTACGCCGTG 
ATTGACCTCA AAAAGACCGT GGCCATGTCC AACCTGCAGA GAGCTCTGCC CCGAGACGAT 
GGCACCGCCA GGAAAACCCG GCACAACAGC ACCGACCTGC CTCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Phospho-tyrosine dependent protein-protein interaction network.
Molecular systems biology11(3)794(2015 Mar)
Grossmann A,Benlasfer N,Birth P,Hegele A,Wachsmuth F,Apelt L,Stelzl U

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
Nature514(7520)92-97(2014 Oct)
Perry JR,Day F,Elks CE,Sulem P,Thompson DJ,Ferreira T,He C,Chasman DI,Esko T,Thorleifsson G,Albrecht E,Ang WQ,Corre T,Cousminer DL,Feenstra B,Franceschini N,Ganna A,Johnson AD,Kjellqvist S,Lunetta KL,McMahon G,Nolte IM,Paternoster L,Porcu E,Smith AV,Stolk L,Teumer A,T?ernikova N,Tikkanen E,Ulivi S,Wagner EK,Amin N,Bierut LJ,Byrne EM,Hottenga JJ,Koller DL,Mangino M,Pers TH,Yerges-Armstrong LM,Zhao JH,Andrulis IL,Anton-Culver H,Atsma F,Bandinelli S,Beckmann MW,Benitez J,Blomqvist C,Bojesen SE,Bolla MK,Bonanni B,Brauch H,Brenner H,Buring JE,Chang-Claude J,Chanock S,Chen J,Chenevix-Trench G,Coll?e JM,Couch FJ,Couper D,Coveillo AD,Cox A,Czene K,D'adamo AP,Smith GD,De Vivo I,Demerath EW,Dennis J,Devilee P,Dieffenbach AK,Dunning AM,Eiriksdottir G,Eriksson JG,Fasching PA,Ferrucci L,Flesch-Janys D,Flyger H,Foroud T,Franke L,Garcia ME,Garc?a-Closas M,Geller F,de Geus EE,Giles GG,Gudbjartsson DF,Gudnason V,Gu?nel P,Guo S,Hall P,Hamann U,Haring R,Hartman CA,Heath AC,Hofman A,Hooning MJ,Hopper JL,Hu FB,Hunter DJ,Karasik D,Kiel DP,Knight JA,Kosma VM,Kutalik Z,Lai S,Lambrechts D,Lindblom A,M?gi R,Magnusson PK,Mannermaa A,Martin NG,Masson G,McArdle PF,McArdle WL,Melbye M,Michailidou K,Mihailov E,Milani L,Milne RL,Nevanlinna H,Neven P,Nohr EA,Oldehinkel AJ,Oostra BA,Palotie A,Peacock M,Pedersen NL,Peterlongo P,Peto J,Pharoah PD,Postma DS,Pouta A,Pylk?s K,Radice P,Ring S,Rivadeneira F,Robino A,Rose LM,Rudolph A,Salomaa V,Sanna S,Schlessinger D,Schmidt MK,Southey MC,Sovio U,Stampfer MJ,St?ckl D,Storniolo AM,Timpson NJ,Tyrer J,Visser JA,Vollenweider P,V?lzke H,Waeber G,Waldenberger M,Wallaschofski H,Wang Q,Willemsen G,Winqvist R,Wolffenbuttel BH,Wright MJ,,,,,,,Boomsma DI,Econs MJ,Khaw KT,Loos RJ,McCarthy MI,Montgomery GW,Rice JP,Streeten EA,Thorsteinsdottir U,van Duijn CM,Alizadeh BZ,Bergmann S,Boerwinkle E,Boyd HA,Crisponi L,Gasparini P,Gieger C,Harris TB,Ingelsson E,J?rvelin MR,Kraft P,Lawlor D,Metspalu A,Pennell CE,Ridker PM,Snieder H,S?rensen TI,Spector TD,Strachan DP,Uitterlinden AG,Wareham NJ,Widen E,Zygmunt M,Murray A,Easton DF,Stefansson K,Murabito JM,Ong KK

Adaptor protein complex of FRS2? and CIN85/CD2AP provides a novel mechanism for ErbB2/HER2 protein downregulation.
Cancer science104(3)345-52(2013 Mar)
Minegishi Y,Shibagaki Y,Mizutani A,Fujita K,Tezuka T,Kinoshita M,Kuroda M,Hattori S,Gotoh N

FRS2beta, a potential prognostic gene for non-small cell lung cancer, encodes a feedback inhibitor of EGF receptor family members by ERK binding.
Oncogene29(21)3087-99(2010 May)
Iejima D,Minegishi Y,Takenaka K,Siswanto A,Watanabe M,Huang L,Watanabe T,Tanaka F,Kuroda M,Gotoh N

Hepatitis C virus infection protein network.
Molecular systems biology4230(2008)
de Chassey B,Navratil V,Tafforeau L,Hiet MS,Aublin-Gex A,Agaugu? S,Meiffren G,Pradezynski F,Faria BF,Chantier T,Le Breton M,Pellet J,Davoust N,Mangeot PE,Chaboud A,Penin F,Jacob Y,Vidalain PO,Vidal M,Andr? P,Rabourdin-Combe C,Lotteau V

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FRS3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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