FAM189B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FAM189B
Entrez Gene ID	10712
Full Name	family with sequence similarity 189 member B
Synonyms	C1orf2,COTE1
General protein information	Preferred Names family with sequence similarity 189 member B Names protein FAM189B
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q22
Summary	This gene is located near the gene for the lysosomal enzyme glucosylceramidase; a deficiency in this enzyme is associated with Gaucher disease. The encoded protein has been identified as a potential binding partner of a WW domain-containing protein which is involved in apoptosis and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001267608.1	NP_001254537.1	protein FAM189B isoform c
NM_006589.3	NP_006580.2	protein FAM189B isoform a
NM_198264.2	NP_937995.1	protein FAM189B isoform b
NM_006589.2	NP_006580.2	protein FAM189B isoform a
XM_005244845.1	XP_005244902.1	protein FAM189B isoform X1
NM_001267608.2	NP_001254537.1	protein FAM189B isoform c
XM_005244845.2	XP_005244902.1	protein FAM189B isoform X1
NM_198264.1	NP_937995.1	protein FAM189B isoform b

Pathways from BioSystems

Homologies

Homo sapiens (human)	FAM189B	NP_006580.2
Bos taurus (cattle)	FAM189B	XP_005203849.1
Mus musculus (house mouse)	Fam189b	NP_001014995.1
Danio rerio (zebrafish)	LOC101882768	XP_005158202.1
Pan troglodytes (chimpanzee)	FAM189B	XP_001155325.1
Rattus norvegicus (Norway rat)	Fam189b	NP_001101160.1
Canis lupus familiaris (dog)	FAM189B	XP_547550.2

Gene Ontology
Bibliography

Related articles in PubMed

Upregulation of the putative oncogene COTE1 contributes to human hepatocarcinogenesis through modulation of WWOX signaling.
Zhang H, Tian Y, Shen J, Wang Y, Xu Y, Wang Y, Han Z, Li X
International journal of oncology45(2)719-31(2014 Aug)

Ectopic overexpression of COTE1 promotes cellular invasion of hepatocellular carcinoma.
Zhang H, Huang CJ, Tian Y, Wang YP, Han ZG, Li XC
Asian Pacific journal of cancer prevention : APJCP13(11)5799-804(2012)

SREBP-1 regulates the expression of heme oxygenase 1 and the phosphatidylinositol-3 kinase regulatory subunit p55 gamma.
Kallin A, Johannessen LE, Cani PD, Marbehant CY, Essaghir A, Foufelle F, Ferr? P, Heldin CH, Delzenne NM, Demoulin JB
Journal of lipid research48(7)1628-36(2007 Jul)

WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins.
Ludes-Meyers JH, Kil H, Bednarek AK, Drake J, Bedford MT, Aldaz CM
Oncogene23(29)5049-55(2004 Jun)

Identification of three additional genes contiguous to the glucocerebrosidase locus on chromosome 1q21: implications for Gaucher disease.
Winfield SL, Tayebi N, Martin BM, Ginns EI, Sidransky E
Genome research7(10)1020-6(1997 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

our findings suggest that the cytoplasmic protein COTE1 contributes to hepatocellular carcinoma tumorigenesis by regulating cell proliferation through the modulation of WWOX signaling
Title: Upregulation of the putative oncogene COTE1 contributes to human hepatocarcinogenesis through modulation of WWOX signaling.

Overexpression of COTE1 promotes cellular invasion of hepatocellular carcinoma.
Title: Ectopic overexpression of COTE1 promotes cellular invasion of hepatocellular carcinoma.

The following FAM189B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FAM189B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02524	NM_198264.2 Latest version!	Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu05562	NM_006589.3 Latest version!	Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu11445	NM_001267608.2 Latest version!	Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu34080	XM_005244845.2 Latest version!	Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
View Old Accession Versions >>
OHu05562	NM_006589.2	Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu11445	NM_001267608.1	Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu34080	XM_005244845.1	Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
OHu02524	NM_198264.1	Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FAM189B ( NM_198264.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_937995.1 Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02524
Clone ID Related Accession (Same CDS sequence)	NM_198264.2 , NM_198264.1
Accession Version	NM_198264.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1719bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	protein FAM189B isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK093335.1 and BC040136.1. On Jun 1, 2019 this sequence version replaced NM_198264.1. Transcript Variant: This variant (2) lacks an in-frame portion of the 5' coding region compared to variant 1. The resulting protein (isoform b) is shorter than isoform a. ##Evidence-Data-START## Transcript exon combination :: BC040136.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGCCCT CGCCTAGTGA CTCCAGCCGC TCGCTGACCA GCCGGCCCAG CACCAGGGGC 
CTTACCCACC TCCGCCTCCA CCGACCCTGG CTGCAGGCCC TGCTTACGCT GGGGCTGGTC 
CAAGTGCTCC TGGGCATCCT GGTGGTCACC TTCAGCATGG TGGCCTCTTC CGTCACCACC 
ACCGAGAGCA TCAAGAGGTC CTGCCCGTCT TGGGCTGGGT TCTCGAACCT GCTCTTCAGC 
GTCTGTGGGC TCACCATTTG TGCCGCTATA ATCTGTACAC TCTCTGCTAT TGTCTGCTGC 
ATCCAAATCT TCTCCCTGGA CCTCGTGCAT ACGCTGGCCC CTGAGCGGTC AGTCTCAGGC 
CCACTGGGAC CTCTGGGCTG CACGTCCCCG CCCCCAGCCC CTCTCCTACA CACCATGCTG 
GACCTGGAGG AATTTGTCCC GCCTGTGCCC CCACCGCCCT ACTATCCCCC AGAGTATACC 
TGCAGCTCAG AAACAGATGC ACAGAGCATC ACGTACAATG GCTCCATGGA CAGCCCAGTG 
CCCTTGTACC CTACCGATTG CCCCCCTTCT TATGAGGCAG TCATGGGACT ACGAGGAGAC 
AGCCAGGCCA CTCTCTTTGA CCCTCAGCTT CACGATGGCT CGTGCATCTG TGAACGAGTG 
GCCTCCATTG TAGACGTGTC CATGGACAGC GGGTCTCTGG TGCTGTCAGC CATTGGTGAC 
CTCCCTGGGG GCTCTAGCCC GTCGGAGGAC TCGTGCCTGC TGGAGCTGCA GGGCTCCGTG 
CGCTCCGTGG ACTACGTTCT CTTTCGCTCC ATCCAGCGCA GCCGTGCCGG CTACTGCCTC 
AGCCTGGACT GTGGCCTGCG GGGCCCCTTC GAGGAAAGCC CCCTGCCACG GCGCCCCCCA 
CGGGCTGCCC GCTCCTATTC CTGCTCTGCC CCTGAAGCTC CACCCCCACT GGGTGCCCCC 
ACAGCTGCCC GCAGCTGCCA CCGGTTGGAG GGCTGGCCGC CCTGGGTGGG ACCCTGCTTC 
CCCGAGCTGA GGCGGCGGGT CCCCCGGGGA GGGGGCCGCC CAGCCGCAGC CCCGCCCACC 
CGAGCCCCGA CTCGTCGCTT CAGCGATAGC TCAGGTTCCC TCACCCCACC GGGGCACCGG 
CCTCCTCATC CGGCATCCCC ACCACCGCTG CTGCTGCCAC GGTCCCACAG CGACCCAGGC 
ATCACGACCT CCAGTGACAC TGCTGACTTC AGGGACCTTT ATACCAAAGT GCTTGAGGAA 
GAAGCTGCTT CTGTTTCCTC TGCAGATACA GGGCTCTGCT CTGAAGCCTG CCTCTTCCGC 
CTAGCCCGCT GCCCTTCCCC CAAGTTGCTA CGTGCCCGGT CAGCCGAGAA ACGGCGCCCT 
GTGCCCACCT TCCAAAAAGT TCCCCTGCCC TCGGGCCCTG CACCTGCCCA CTCCCTGGGG 
GACCTAAAGG GCAGCTGGCC AGGTCGGGGC CTGGTCACTC GTTTCCTCCA GATATCCAGG 
AAAGCCCCAG ACCCCAGTGG GACTGGAGCT CATGGACATA AGCAGGTGCC CCGGAGCCTG 
TGGGGCCGGC CTGGCCGAGA GAGCCTCCAC CTTCGCAGCT GCGGAGATCT GAGCTCTAGC 
TCTTCCCTGC GGCGTCTCCT GTCTGGCCGC AGGCTGGAGC GTGGTACCCG CCCCCACAGC 
CTCAGCCTCA ACGGGGGCAG CCGGGAGACT GGGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_937995.1
CDS	607..2325
Translation	MMPSPSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTTTESIKRSCPSWAGFSNLLFSVCGLTICAAIICTLSAIVCCIQIFSLDLVHTLAPERSVSGPLGPLGCTSPPPAPLLHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPSYEAVMGLRGDSQATLFDPQLHDGSCICERVASIVDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQRSRAGYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLPRSHSDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPKLLRARSAEKRRPVPTFQKVPLPSGPAPAHSLGDLKGSWPGRGLVTRFLQISRKAPDPSGTGAHGHKQVPRSLWGRPGRESLHLRSCGDLSSSSSLRRLLSGRRLERGTRPHSLSLNGGSRETGL

Target ORF information:

RefSeq Version	NM_198264.2
Organism	Homo sapiens(human)
Definition	Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198264.2

ORF Insert Sequence:

ATGATGCCCT CGCCTAGTGA CTCCAGCCGC TCGCTGACCA GCCGGCCCAG CACCAGGGGC 
CTTACCCACC TCCGCCTCCA CCGACCCTGG CTGCAGGCCC TGCTTACGCT GGGGCTGGTC 
CAAGTGCTCC TGGGCATCCT GGTGGTCACC TTCAGCATGG TGGCCTCTTC CGTCACCACC 
ACCGAGAGCA TCAAGAGGTC CTGCCCGTCT TGGGCTGGGT TCTCGAACCT GCTCTTCAGC 
GTCTGTGGGC TCACCATTTG TGCCGCTATA ATCTGTACAC TCTCTGCTAT TGTCTGCTGC 
ATCCAAATCT TCTCCCTGGA CCTCGTGCAT ACGCTGGCCC CTGAGCGGTC AGTCTCAGGC 
CCACTGGGAC CTCTGGGCTG CACGTCCCCG CCCCCAGCCC CTCTCCTACA CACCATGCTG 
GACCTGGAGG AATTTGTCCC GCCTGTGCCC CCACCGCCCT ACTATCCCCC AGAGTATACC 
TGCAGCTCAG AAACAGATGC ACAGAGCATC ACGTACAATG GCTCCATGGA CAGCCCAGTG 
CCCTTGTACC CTACCGATTG CCCCCCTTCT TATGAGGCAG TCATGGGACT ACGAGGAGAC 
AGCCAGGCCA CTCTCTTTGA CCCTCAGCTT CACGATGGCT CGTGCATCTG TGAACGAGTG 
GCCTCCATTG TAGACGTGTC CATGGACAGC GGGTCTCTGG TGCTGTCAGC CATTGGTGAC 
CTCCCTGGGG GCTCTAGCCC GTCGGAGGAC TCGTGCCTGC TGGAGCTGCA GGGCTCCGTG 
CGCTCCGTGG ACTACGTTCT CTTTCGCTCC ATCCAGCGCA GCCGTGCCGG CTACTGCCTC 
AGCCTGGACT GTGGCCTGCG GGGCCCCTTC GAGGAAAGCC CCCTGCCACG GCGCCCCCCA 
CGGGCTGCCC GCTCCTATTC CTGCTCTGCC CCTGAAGCTC CACCCCCACT GGGTGCCCCC 
ACAGCTGCCC GCAGCTGCCA CCGGTTGGAG GGCTGGCCGC CCTGGGTGGG ACCCTGCTTC 
CCCGAGCTGA GGCGGCGGGT CCCCCGGGGA GGGGGCCGCC CAGCCGCAGC CCCGCCCACC 
CGAGCCCCGA CTCGTCGCTT CAGCGATAGC TCAGGTTCCC TCACCCCACC GGGGCACCGG 
CCTCCTCATC CGGCATCCCC ACCACCGCTG CTGCTGCCAC GGTCCCACAG CGACCCAGGC 
ATCACGACCT CCAGTGACAC TGCTGACTTC AGGGACCTTT ATACCAAAGT GCTTGAGGAA 
GAAGCTGCTT CTGTTTCCTC TGCAGATACA GGGCTCTGCT CTGAAGCCTG CCTCTTCCGC 
CTAGCCCGCT GCCCTTCCCC CAAGTTGCTA CGTGCCCGGT CAGCCGAGAA ACGGCGCCCT 
GTGCCCACCT TCCAAAAAGT TCCCCTGCCC TCGGGCCCTG CACCTGCCCA CTCCCTGGGG 
GACCTAAAGG GCAGCTGGCC AGGTCGGGGC CTGGTCACTC GTTTCCTCCA GATATCCAGG 
AAAGCCCCAG ACCCCAGTGG GACTGGAGCT CATGGACATA AGCAGGTGCC CCGGAGCCTG 
TGGGGCCGGC CTGGCCGAGA GAGCCTCCAC CTTCGCAGCT GCGGAGATCT GAGCTCTAGC 
TCTTCCCTGC GGCGTCTCCT GTCTGGCCGC AGGCTGGAGC GTGGTACCCG CCCCCACAGC 
CTCAGCCTCA ACGGGGGCAG CCGGGAGACT GGGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FAM189B ( NM_198264.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_937995.1 Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02524
Clone ID Related Accession (Same CDS sequence)	NM_198264.2 , NM_198264.1
Accession Version	NM_198264.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1719bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-22
Organism	Homo sapiens(human)
Product	protein FAM189B isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK093335.1 and BC040136.1. Transcript Variant: This variant (2) lacks an in-frame portion of the 5' coding region compared to variant 1. The resulting protein (isoform b) is shorter than isoform a. ##Evidence-Data-START## Transcript exon combination :: BC040136.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGCCCT CGCCTAGTGA CTCCAGCCGC TCGCTGACCA GCCGGCCCAG CACCAGGGGC 
CTTACCCACC TCCGCCTCCA CCGACCCTGG CTGCAGGCCC TGCTTACGCT GGGGCTGGTC 
CAAGTGCTCC TGGGCATCCT GGTGGTCACC TTCAGCATGG TGGCCTCTTC CGTCACCACC 
ACCGAGAGCA TCAAGAGGTC CTGCCCGTCT TGGGCTGGGT TCTCGAACCT GCTCTTCAGC 
GTCTGTGGGC TCACCATTTG TGCCGCTATA ATCTGTACAC TCTCTGCTAT TGTCTGCTGC 
ATCCAAATCT TCTCCCTGGA CCTCGTGCAT ACGCTGGCCC CTGAGCGGTC AGTCTCAGGC 
CCACTGGGAC CTCTGGGCTG CACGTCCCCG CCCCCAGCCC CTCTCCTACA CACCATGCTG 
GACCTGGAGG AATTTGTCCC GCCTGTGCCC CCACCGCCCT ACTATCCCCC AGAGTATACC 
TGCAGCTCAG AAACAGATGC ACAGAGCATC ACGTACAATG GCTCCATGGA CAGCCCAGTG 
CCCTTGTACC CTACCGATTG CCCCCCTTCT TATGAGGCAG TCATGGGACT ACGAGGAGAC 
AGCCAGGCCA CTCTCTTTGA CCCTCAGCTT CACGATGGCT CGTGCATCTG TGAACGAGTG 
GCCTCCATTG TAGACGTGTC CATGGACAGC GGGTCTCTGG TGCTGTCAGC CATTGGTGAC 
CTCCCTGGGG GCTCTAGCCC GTCGGAGGAC TCGTGCCTGC TGGAGCTGCA GGGCTCCGTG 
CGCTCCGTGG ACTACGTTCT CTTTCGCTCC ATCCAGCGCA GCCGTGCCGG CTACTGCCTC 
AGCCTGGACT GTGGCCTGCG GGGCCCCTTC GAGGAAAGCC CCCTGCCACG GCGCCCCCCA 
CGGGCTGCCC GCTCCTATTC CTGCTCTGCC CCTGAAGCTC CACCCCCACT GGGTGCCCCC 
ACAGCTGCCC GCAGCTGCCA CCGGTTGGAG GGCTGGCCGC CCTGGGTGGG ACCCTGCTTC 
CCCGAGCTGA GGCGGCGGGT CCCCCGGGGA GGGGGCCGCC CAGCCGCAGC CCCGCCCACC 
CGAGCCCCGA CTCGTCGCTT CAGCGATAGC TCAGGTTCCC TCACCCCACC GGGGCACCGG 
CCTCCTCATC CGGCATCCCC ACCACCGCTG CTGCTGCCAC GGTCCCACAG CGACCCAGGC 
ATCACGACCT CCAGTGACAC TGCTGACTTC AGGGACCTTT ATACCAAAGT GCTTGAGGAA 
GAAGCTGCTT CTGTTTCCTC TGCAGATACA GGGCTCTGCT CTGAAGCCTG CCTCTTCCGC 
CTAGCCCGCT GCCCTTCCCC CAAGTTGCTA CGTGCCCGGT CAGCCGAGAA ACGGCGCCCT 
GTGCCCACCT TCCAAAAAGT TCCCCTGCCC TCGGGCCCTG CACCTGCCCA CTCCCTGGGG 
GACCTAAAGG GCAGCTGGCC AGGTCGGGGC CTGGTCACTC GTTTCCTCCA GATATCCAGG 
AAAGCCCCAG ACCCCAGTGG GACTGGAGCT CATGGACATA AGCAGGTGCC CCGGAGCCTG 
TGGGGCCGGC CTGGCCGAGA GAGCCTCCAC CTTCGCAGCT GCGGAGATCT GAGCTCTAGC 
TCTTCCCTGC GGCGTCTCCT GTCTGGCCGC AGGCTGGAGC GTGGTACCCG CCCCCACAGC 
CTCAGCCTCA ACGGGGGCAG CCGGGAGACT GGGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_937995.1
CDS	607..2325
Translation	MMPSPSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTTTESIKRSCPSWAGFSNLLFSVCGLTICAAIICTLSAIVCCIQIFSLDLVHTLAPERSVSGPLGPLGCTSPPPAPLLHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPSYEAVMGLRGDSQATLFDPQLHDGSCICERVASIVDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQRSRAGYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLPRSHSDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPKLLRARSAEKRRPVPTFQKVPLPSGPAPAHSLGDLKGSWPGRGLVTRFLQISRKAPDPSGTGAHGHKQVPRSLWGRPGRESLHLRSCGDLSSSSSLRRLLSGRRLERGTRPHSLSLNGGSRETGL

Target ORF information:

RefSeq Version	NM_198264.1
Organism	Homo sapiens(human)
Definition	Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198264.1

ORF Insert Sequence:

ATGATGCCCT CGCCTAGTGA CTCCAGCCGC TCGCTGACCA GCCGGCCCAG CACCAGGGGC 
CTTACCCACC TCCGCCTCCA CCGACCCTGG CTGCAGGCCC TGCTTACGCT GGGGCTGGTC 
CAAGTGCTCC TGGGCATCCT GGTGGTCACC TTCAGCATGG TGGCCTCTTC CGTCACCACC 
ACCGAGAGCA TCAAGAGGTC CTGCCCGTCT TGGGCTGGGT TCTCGAACCT GCTCTTCAGC 
GTCTGTGGGC TCACCATTTG TGCCGCTATA ATCTGTACAC TCTCTGCTAT TGTCTGCTGC 
ATCCAAATCT TCTCCCTGGA CCTCGTGCAT ACGCTGGCCC CTGAGCGGTC AGTCTCAGGC 
CCACTGGGAC CTCTGGGCTG CACGTCCCCG CCCCCAGCCC CTCTCCTACA CACCATGCTG 
GACCTGGAGG AATTTGTCCC GCCTGTGCCC CCACCGCCCT ACTATCCCCC AGAGTATACC 
TGCAGCTCAG AAACAGATGC ACAGAGCATC ACGTACAATG GCTCCATGGA CAGCCCAGTG 
CCCTTGTACC CTACCGATTG CCCCCCTTCT TATGAGGCAG TCATGGGACT ACGAGGAGAC 
AGCCAGGCCA CTCTCTTTGA CCCTCAGCTT CACGATGGCT CGTGCATCTG TGAACGAGTG 
GCCTCCATTG TAGACGTGTC CATGGACAGC GGGTCTCTGG TGCTGTCAGC CATTGGTGAC 
CTCCCTGGGG GCTCTAGCCC GTCGGAGGAC TCGTGCCTGC TGGAGCTGCA GGGCTCCGTG 
CGCTCCGTGG ACTACGTTCT CTTTCGCTCC ATCCAGCGCA GCCGTGCCGG CTACTGCCTC 
AGCCTGGACT GTGGCCTGCG GGGCCCCTTC GAGGAAAGCC CCCTGCCACG GCGCCCCCCA 
CGGGCTGCCC GCTCCTATTC CTGCTCTGCC CCTGAAGCTC CACCCCCACT GGGTGCCCCC 
ACAGCTGCCC GCAGCTGCCA CCGGTTGGAG GGCTGGCCGC CCTGGGTGGG ACCCTGCTTC 
CCCGAGCTGA GGCGGCGGGT CCCCCGGGGA GGGGGCCGCC CAGCCGCAGC CCCGCCCACC 
CGAGCCCCGA CTCGTCGCTT CAGCGATAGC TCAGGTTCCC TCACCCCACC GGGGCACCGG 
CCTCCTCATC CGGCATCCCC ACCACCGCTG CTGCTGCCAC GGTCCCACAG CGACCCAGGC 
ATCACGACCT CCAGTGACAC TGCTGACTTC AGGGACCTTT ATACCAAAGT GCTTGAGGAA 
GAAGCTGCTT CTGTTTCCTC TGCAGATACA GGGCTCTGCT CTGAAGCCTG CCTCTTCCGC 
CTAGCCCGCT GCCCTTCCCC CAAGTTGCTA CGTGCCCGGT CAGCCGAGAA ACGGCGCCCT 
GTGCCCACCT TCCAAAAAGT TCCCCTGCCC TCGGGCCCTG CACCTGCCCA CTCCCTGGGG 
GACCTAAAGG GCAGCTGGCC AGGTCGGGGC CTGGTCACTC GTTTCCTCCA GATATCCAGG 
AAAGCCCCAG ACCCCAGTGG GACTGGAGCT CATGGACATA AGCAGGTGCC CCGGAGCCTG 
TGGGGCCGGC CTGGCCGAGA GAGCCTCCAC CTTCGCAGCT GCGGAGATCT GAGCTCTAGC 
TCTTCCCTGC GGCGTCTCCT GTCTGGCCGC AGGCTGGAGC GTGGTACCCG CCCCCACAGC 
CTCAGCCTCA ACGGGGGCAG CCGGGAGACT GGGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FAM189B ( NM_006589.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006580.2 Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu05562
Clone ID Related Accession (Same CDS sequence)	NM_006589.3 , NM_006589.2
Accession Version	NM_006589.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2007bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	protein FAM189B isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK093335.1, BC006493.2 and BC040136.1. On Nov 22, 2018 this sequence version replaced NM_006589.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform a). ##Evidence-Data-START## Transcript exon combination :: SRR1163657.27608.1, SRR1163657.186137.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000361361.7/ ENSP00000354958.2 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGATGCCCT CGCCTAGTGA CTCCAGCCGC TCGCTGACCA GCCGGCCCAG CACCAGGGGC 
CTTACCCACC TCCGCCTCCA CCGACCCTGG CTGCAGGCCC TGCTTACGCT GGGGCTGGTC 
CAAGTGCTCC TGGGCATCCT GGTGGTCACC TTCAGCATGG TGGCCTCTTC CGTCACCACC 
ACCGAGAGCA TCAAGAGGTC CTGCCCGTCT TGGGCTGGGT TCTCGCTGGC GTTCTCCGGG 
GTGGTTGGCA TTGTGTCCTG GAAGCGGCCA TTCACTCTAG TGATCTCCTT CTTCTCCTTG 
CTTTCGGTGC TCTGTGTCAT GCTTAGCATG GCTGGCTCTG TTCTCTCCTG TAAGAATGCT 
CAACTGGCCC GAGACTTCCA ACAGTGCTCT CTGGAAGGAA AGGTCTGTGT GTGCTGTCCC 
TCTGTTCCCC TCCTCCGGCC CTGTCCAGAG TCGGGGCAGG AACTGAAAGT TGCCCCTAAC 
TCCACCTGTG ATGAAGCCCG AGGGGCCCTC AAGAACCTGC TCTTCAGCGT CTGTGGGCTC 
ACCATTTGTG CCGCTATAAT CTGTACACTC TCTGCTATTG TCTGCTGCAT CCAAATCTTC 
TCCCTGGACC TCGTGCATAC GCTGGCCCCT GAGCGGTCAG TCTCAGGCCC ACTGGGACCT 
CTGGGCTGCA CGTCCCCGCC CCCAGCCCCT CTCCTACACA CCATGCTGGA CCTGGAGGAA 
TTTGTCCCGC CTGTGCCCCC ACCGCCCTAC TATCCCCCAG AGTATACCTG CAGCTCAGAA 
ACAGATGCAC AGAGCATCAC GTACAATGGC TCCATGGACA GCCCAGTGCC CTTGTACCCT 
ACCGATTGCC CCCCTTCTTA TGAGGCAGTC ATGGGACTAC GAGGAGACAG CCAGGCCACT 
CTCTTTGACC CTCAGCTTCA CGATGGCTCG TGCATCTGTG AACGAGTGGC CTCCATTGTA 
GACGTGTCCA TGGACAGCGG GTCTCTGGTG CTGTCAGCCA TTGGTGACCT CCCTGGGGGC 
TCTAGCCCGT CGGAGGACTC GTGCCTGCTG GAGCTGCAGG GCTCCGTGCG CTCCGTGGAC 
TACGTTCTCT TTCGCTCCAT CCAGCGCAGC CGTGCCGGCT ACTGCCTCAG CCTGGACTGT 
GGCCTGCGGG GCCCCTTCGA GGAAAGCCCC CTGCCACGGC GCCCCCCACG GGCTGCCCGC 
TCCTATTCCT GCTCTGCCCC TGAAGCTCCA CCCCCACTGG GTGCCCCCAC AGCTGCCCGC 
AGCTGCCACC GGTTGGAGGG CTGGCCGCCC TGGGTGGGAC CCTGCTTCCC CGAGCTGAGG 
CGGCGGGTCC CCCGGGGAGG GGGCCGCCCA GCCGCAGCCC CGCCCACCCG AGCCCCGACT 
CGTCGCTTCA GCGATAGCTC AGGTTCCCTC ACCCCACCGG GGCACCGGCC TCCTCATCCG 
GCATCCCCAC CACCGCTGCT GCTGCCACGG TCCCACAGCG ACCCAGGCAT CACGACCTCC 
AGTGACACTG CTGACTTCAG GGACCTTTAT ACCAAAGTGC TTGAGGAAGA AGCTGCTTCT 
GTTTCCTCTG CAGATACAGG GCTCTGCTCT GAAGCCTGCC TCTTCCGCCT AGCCCGCTGC 
CCTTCCCCCA AGTTGCTACG TGCCCGGTCA GCCGAGAAAC GGCGCCCTGT GCCCACCTTC 
CAAAAAGTTC CCCTGCCCTC GGGCCCTGCA CCTGCCCACT CCCTGGGGGA CCTAAAGGGC 
AGCTGGCCAG GTCGGGGCCT GGTCACTCGT TTCCTCCAGA TATCCAGGAA AGCCCCAGAC 
CCCAGTGGGA CTGGAGCTCA TGGACATAAG CAGGTGCCCC GGAGCCTGTG GGGCCGGCCT 
GGCCGAGAGA GCCTCCACCT TCGCAGCTGC GGAGATCTGA GCTCTAGCTC TTCCCTGCGG 
CGTCTCCTGT CTGGCCGCAG GCTGGAGCGT GGTACCCGCC CCCACAGCCT CAGCCTCAAC 
GGGGGCAGCC GGGAGACTGG GCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006580.2
CDS	607..2613
Translation	MMPSPSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTTTESIKRSCPSWAGFSLAFSGVVGIVSWKRPFTLVISFFSLLSVLCVMLSMAGSVLSCKNAQLARDFQQCSLEGKVCVCCPSVPLLRPCPESGQELKVAPNSTCDEARGALKNLLFSVCGLTICAAIICTLSAIVCCIQIFSLDLVHTLAPERSVSGPLGPLGCTSPPPAPLLHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPSYEAVMGLRGDSQATLFDPQLHDGSCICERVASIVDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQRSRAGYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLPRSHSDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPKLLRARSAEKRRPVPTFQKVPLPSGPAPAHSLGDLKGSWPGRGLVTRFLQISRKAPDPSGTGAHGHKQVPRSLWGRPGRESLHLRSCGDLSSSSSLRRLLSGRRLERGTRPHSLSLNGGSRETGL

Target ORF information:

RefSeq Version	NM_006589.3
Organism	Homo sapiens(human)
Definition	Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006589.3

ORF Insert Sequence:

ATGATGCCCT CGCCTAGTGA CTCCAGCCGC TCGCTGACCA GCCGGCCCAG CACCAGGGGC 
CTTACCCACC TCCGCCTCCA CCGACCCTGG CTGCAGGCCC TGCTTACGCT GGGGCTGGTC 
CAAGTGCTCC TGGGCATCCT GGTGGTCACC TTCAGCATGG TGGCCTCTTC CGTCACCACC 
ACCGAGAGCA TCAAGAGGTC CTGCCCGTCT TGGGCTGGGT TCTCGCTGGC GTTCTCCGGG 
GTGGTTGGCA TTGTGTCCTG GAAGCGGCCA TTCACTCTAG TGATCTCCTT CTTCTCCTTG 
CTTTCGGTGC TCTGTGTCAT GCTTAGCATG GCTGGCTCTG TTCTCTCCTG TAAGAATGCT 
CAACTGGCCC GAGACTTCCA ACAGTGCTCT CTGGAAGGAA AGGTCTGTGT GTGCTGTCCC 
TCTGTTCCCC TCCTCCGGCC CTGTCCAGAG TCGGGGCAGG AACTGAAAGT TGCCCCTAAC 
TCCACCTGTG ATGAAGCCCG AGGGGCCCTC AAGAACCTGC TCTTCAGCGT CTGTGGGCTC 
ACCATTTGTG CCGCTATAAT CTGTACACTC TCTGCTATTG TCTGCTGCAT CCAAATCTTC 
TCCCTGGACC TCGTGCATAC GCTGGCCCCT GAGCGGTCAG TCTCAGGCCC ACTGGGACCT 
CTGGGCTGCA CGTCCCCGCC CCCAGCCCCT CTCCTACACA CCATGCTGGA CCTGGAGGAA 
TTTGTCCCGC CTGTGCCCCC ACCGCCCTAC TATCCCCCAG AGTATACCTG CAGCTCAGAA 
ACAGATGCAC AGAGCATCAC GTACAATGGC TCCATGGACA GCCCAGTGCC CTTGTACCCT 
ACCGATTGCC CCCCTTCTTA TGAGGCAGTC ATGGGACTAC GAGGAGACAG CCAGGCCACT 
CTCTTTGACC CTCAGCTTCA CGATGGCTCG TGCATCTGTG AACGAGTGGC CTCCATTGTA 
GACGTGTCCA TGGACAGCGG GTCTCTGGTG CTGTCAGCCA TTGGTGACCT CCCTGGGGGC 
TCTAGCCCGT CGGAGGACTC GTGCCTGCTG GAGCTGCAGG GCTCCGTGCG CTCCGTGGAC 
TACGTTCTCT TTCGCTCCAT CCAGCGCAGC CGTGCCGGCT ACTGCCTCAG CCTGGACTGT 
GGCCTGCGGG GCCCCTTCGA GGAAAGCCCC CTGCCACGGC GCCCCCCACG GGCTGCCCGC 
TCCTATTCCT GCTCTGCCCC TGAAGCTCCA CCCCCACTGG GTGCCCCCAC AGCTGCCCGC 
AGCTGCCACC GGTTGGAGGG CTGGCCGCCC TGGGTGGGAC CCTGCTTCCC CGAGCTGAGG 
CGGCGGGTCC CCCGGGGAGG GGGCCGCCCA GCCGCAGCCC CGCCCACCCG AGCCCCGACT 
CGTCGCTTCA GCGATAGCTC AGGTTCCCTC ACCCCACCGG GGCACCGGCC TCCTCATCCG 
GCATCCCCAC CACCGCTGCT GCTGCCACGG TCCCACAGCG ACCCAGGCAT CACGACCTCC 
AGTGACACTG CTGACTTCAG GGACCTTTAT ACCAAAGTGC TTGAGGAAGA AGCTGCTTCT 
GTTTCCTCTG CAGATACAGG GCTCTGCTCT GAAGCCTGCC TCTTCCGCCT AGCCCGCTGC 
CCTTCCCCCA AGTTGCTACG TGCCCGGTCA GCCGAGAAAC GGCGCCCTGT GCCCACCTTC 
CAAAAAGTTC CCCTGCCCTC GGGCCCTGCA CCTGCCCACT CCCTGGGGGA CCTAAAGGGC 
AGCTGGCCAG GTCGGGGCCT GGTCACTCGT TTCCTCCAGA TATCCAGGAA AGCCCCAGAC 
CCCAGTGGGA CTGGAGCTCA TGGACATAAG CAGGTGCCCC GGAGCCTGTG GGGCCGGCCT 
GGCCGAGAGA GCCTCCACCT TCGCAGCTGC GGAGATCTGA GCTCTAGCTC TTCCCTGCGG 
CGTCTCCTGT CTGGCCGCAG GCTGGAGCGT GGTACCCGCC CCCACAGCCT CAGCCTCAAC 
GGGGGCAGCC GGGAGACTGG GCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FAM189B ( NM_006589.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_006580.2 Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant 1, mRNA.

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CloneID	OHu05562
Clone ID Related Accession (Same CDS sequence)	NM_006589.3 , NM_006589.2
Accession Version	NM_006589.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2007bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	protein FAM189B isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK093335.1, BC006493.2 and BC040136.1. On Nov 3, 2003 this sequence version replaced NM_006589.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform a). ##Evidence-Data-START## Transcript exon combination :: SRR1163657.27608.1, SRR1163657.186137.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGCCCT CGCCTAGTGA CTCCAGCCGC TCGCTGACCA GCCGGCCCAG CACCAGGGGC 
CTTACCCACC TCCGCCTCCA CCGACCCTGG CTGCAGGCCC TGCTTACGCT GGGGCTGGTC 
CAAGTGCTCC TGGGCATCCT GGTGGTCACC TTCAGCATGG TGGCCTCTTC CGTCACCACC 
ACCGAGAGCA TCAAGAGGTC CTGCCCGTCT TGGGCTGGGT TCTCGCTGGC GTTCTCCGGG 
GTGGTTGGCA TTGTGTCCTG GAAGCGGCCA TTCACTCTAG TGATCTCCTT CTTCTCCTTG 
CTTTCGGTGC TCTGTGTCAT GCTTAGCATG GCTGGCTCTG TTCTCTCCTG TAAGAATGCT 
CAACTGGCCC GAGACTTCCA ACAGTGCTCT CTGGAAGGAA AGGTCTGTGT GTGCTGTCCC 
TCTGTTCCCC TCCTCCGGCC CTGTCCAGAG TCGGGGCAGG AACTGAAAGT TGCCCCTAAC 
TCCACCTGTG ATGAAGCCCG AGGGGCCCTC AAGAACCTGC TCTTCAGCGT CTGTGGGCTC 
ACCATTTGTG CCGCTATAAT CTGTACACTC TCTGCTATTG TCTGCTGCAT CCAAATCTTC 
TCCCTGGACC TCGTGCATAC GCTGGCCCCT GAGCGGTCAG TCTCAGGCCC ACTGGGACCT 
CTGGGCTGCA CGTCCCCGCC CCCAGCCCCT CTCCTACACA CCATGCTGGA CCTGGAGGAA 
TTTGTCCCGC CTGTGCCCCC ACCGCCCTAC TATCCCCCAG AGTATACCTG CAGCTCAGAA 
ACAGATGCAC AGAGCATCAC GTACAATGGC TCCATGGACA GCCCAGTGCC CTTGTACCCT 
ACCGATTGCC CCCCTTCTTA TGAGGCAGTC ATGGGACTAC GAGGAGACAG CCAGGCCACT 
CTCTTTGACC CTCAGCTTCA CGATGGCTCG TGCATCTGTG AACGAGTGGC CTCCATTGTA 
GACGTGTCCA TGGACAGCGG GTCTCTGGTG CTGTCAGCCA TTGGTGACCT CCCTGGGGGC 
TCTAGCCCGT CGGAGGACTC GTGCCTGCTG GAGCTGCAGG GCTCCGTGCG CTCCGTGGAC 
TACGTTCTCT TTCGCTCCAT CCAGCGCAGC CGTGCCGGCT ACTGCCTCAG CCTGGACTGT 
GGCCTGCGGG GCCCCTTCGA GGAAAGCCCC CTGCCACGGC GCCCCCCACG GGCTGCCCGC 
TCCTATTCCT GCTCTGCCCC TGAAGCTCCA CCCCCACTGG GTGCCCCCAC AGCTGCCCGC 
AGCTGCCACC GGTTGGAGGG CTGGCCGCCC TGGGTGGGAC CCTGCTTCCC CGAGCTGAGG 
CGGCGGGTCC CCCGGGGAGG GGGCCGCCCA GCCGCAGCCC CGCCCACCCG AGCCCCGACT 
CGTCGCTTCA GCGATAGCTC AGGTTCCCTC ACCCCACCGG GGCACCGGCC TCCTCATCCG 
GCATCCCCAC CACCGCTGCT GCTGCCACGG TCCCACAGCG ACCCAGGCAT CACGACCTCC 
AGTGACACTG CTGACTTCAG GGACCTTTAT ACCAAAGTGC TTGAGGAAGA AGCTGCTTCT 
GTTTCCTCTG CAGATACAGG GCTCTGCTCT GAAGCCTGCC TCTTCCGCCT AGCCCGCTGC 
CCTTCCCCCA AGTTGCTACG TGCCCGGTCA GCCGAGAAAC GGCGCCCTGT GCCCACCTTC 
CAAAAAGTTC CCCTGCCCTC GGGCCCTGCA CCTGCCCACT CCCTGGGGGA CCTAAAGGGC 
AGCTGGCCAG GTCGGGGCCT GGTCACTCGT TTCCTCCAGA TATCCAGGAA AGCCCCAGAC 
CCCAGTGGGA CTGGAGCTCA TGGACATAAG CAGGTGCCCC GGAGCCTGTG GGGCCGGCCT 
GGCCGAGAGA GCCTCCACCT TCGCAGCTGC GGAGATCTGA GCTCTAGCTC TTCCCTGCGG 
CGTCTCCTGT CTGGCCGCAG GCTGGAGCGT GGTACCCGCC CCCACAGCCT CAGCCTCAAC 
GGGGGCAGCC GGGAGACTGG GCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006580.2
CDS	607..2613
Translation	MMPSPSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTTTESIKRSCPSWAGFSLAFSGVVGIVSWKRPFTLVISFFSLLSVLCVMLSMAGSVLSCKNAQLARDFQQCSLEGKVCVCCPSVPLLRPCPESGQELKVAPNSTCDEARGALKNLLFSVCGLTICAAIICTLSAIVCCIQIFSLDLVHTLAPERSVSGPLGPLGCTSPPPAPLLHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPSYEAVMGLRGDSQATLFDPQLHDGSCICERVASIVDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQRSRAGYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLPRSHSDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPKLLRARSAEKRRPVPTFQKVPLPSGPAPAHSLGDLKGSWPGRGLVTRFLQISRKAPDPSGTGAHGHKQVPRSLWGRPGRESLHLRSCGDLSSSSSLRRLLSGRRLERGTRPHSLSLNGGSRETGL

Target ORF information:

RefSeq Version	NM_006589.2
Organism	Homo sapiens(human)
Definition	Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006589.2

ORF Insert Sequence:

ATGATGCCCT CGCCTAGTGA CTCCAGCCGC TCGCTGACCA GCCGGCCCAG CACCAGGGGC 
CTTACCCACC TCCGCCTCCA CCGACCCTGG CTGCAGGCCC TGCTTACGCT GGGGCTGGTC 
CAAGTGCTCC TGGGCATCCT GGTGGTCACC TTCAGCATGG TGGCCTCTTC CGTCACCACC 
ACCGAGAGCA TCAAGAGGTC CTGCCCGTCT TGGGCTGGGT TCTCGCTGGC GTTCTCCGGG 
GTGGTTGGCA TTGTGTCCTG GAAGCGGCCA TTCACTCTAG TGATCTCCTT CTTCTCCTTG 
CTTTCGGTGC TCTGTGTCAT GCTTAGCATG GCTGGCTCTG TTCTCTCCTG TAAGAATGCT 
CAACTGGCCC GAGACTTCCA ACAGTGCTCT CTGGAAGGAA AGGTCTGTGT GTGCTGTCCC 
TCTGTTCCCC TCCTCCGGCC CTGTCCAGAG TCGGGGCAGG AACTGAAAGT TGCCCCTAAC 
TCCACCTGTG ATGAAGCCCG AGGGGCCCTC AAGAACCTGC TCTTCAGCGT CTGTGGGCTC 
ACCATTTGTG CCGCTATAAT CTGTACACTC TCTGCTATTG TCTGCTGCAT CCAAATCTTC 
TCCCTGGACC TCGTGCATAC GCTGGCCCCT GAGCGGTCAG TCTCAGGCCC ACTGGGACCT 
CTGGGCTGCA CGTCCCCGCC CCCAGCCCCT CTCCTACACA CCATGCTGGA CCTGGAGGAA 
TTTGTCCCGC CTGTGCCCCC ACCGCCCTAC TATCCCCCAG AGTATACCTG CAGCTCAGAA 
ACAGATGCAC AGAGCATCAC GTACAATGGC TCCATGGACA GCCCAGTGCC CTTGTACCCT 
ACCGATTGCC CCCCTTCTTA TGAGGCAGTC ATGGGACTAC GAGGAGACAG CCAGGCCACT 
CTCTTTGACC CTCAGCTTCA CGATGGCTCG TGCATCTGTG AACGAGTGGC CTCCATTGTA 
GACGTGTCCA TGGACAGCGG GTCTCTGGTG CTGTCAGCCA TTGGTGACCT CCCTGGGGGC 
TCTAGCCCGT CGGAGGACTC GTGCCTGCTG GAGCTGCAGG GCTCCGTGCG CTCCGTGGAC 
TACGTTCTCT TTCGCTCCAT CCAGCGCAGC CGTGCCGGCT ACTGCCTCAG CCTGGACTGT 
GGCCTGCGGG GCCCCTTCGA GGAAAGCCCC CTGCCACGGC GCCCCCCACG GGCTGCCCGC 
TCCTATTCCT GCTCTGCCCC TGAAGCTCCA CCCCCACTGG GTGCCCCCAC AGCTGCCCGC 
AGCTGCCACC GGTTGGAGGG CTGGCCGCCC TGGGTGGGAC CCTGCTTCCC CGAGCTGAGG 
CGGCGGGTCC CCCGGGGAGG GGGCCGCCCA GCCGCAGCCC CGCCCACCCG AGCCCCGACT 
CGTCGCTTCA GCGATAGCTC AGGTTCCCTC ACCCCACCGG GGCACCGGCC TCCTCATCCG 
GCATCCCCAC CACCGCTGCT GCTGCCACGG TCCCACAGCG ACCCAGGCAT CACGACCTCC 
AGTGACACTG CTGACTTCAG GGACCTTTAT ACCAAAGTGC TTGAGGAAGA AGCTGCTTCT 
GTTTCCTCTG CAGATACAGG GCTCTGCTCT GAAGCCTGCC TCTTCCGCCT AGCCCGCTGC 
CCTTCCCCCA AGTTGCTACG TGCCCGGTCA GCCGAGAAAC GGCGCCCTGT GCCCACCTTC 
CAAAAAGTTC CCCTGCCCTC GGGCCCTGCA CCTGCCCACT CCCTGGGGGA CCTAAAGGGC 
AGCTGGCCAG GTCGGGGCCT GGTCACTCGT TTCCTCCAGA TATCCAGGAA AGCCCCAGAC 
CCCAGTGGGA CTGGAGCTCA TGGACATAAG CAGGTGCCCC GGAGCCTGTG GGGCCGGCCT 
GGCCGAGAGA GCCTCCACCT TCGCAGCTGC GGAGATCTGA GCTCTAGCTC TTCCCTGCGG 
CGTCTCCTGT CTGGCCGCAG GCTGGAGCGT GGTACCCGCC CCCACAGCCT CAGCCTCAAC 
GGGGGCAGCC GGGAGACTGG GCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FAM189B ( NM_001267608.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001254537.1 Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant 3, mRNA.

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CloneID	OHu11445
Clone ID Related Accession (Same CDS sequence)	NM_001267608.1 , NM_001267608.2
Accession Version	NM_001267608.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1953bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-06
Organism	Homo sapiens(human)
Product	protein FAM189B isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL713999.28, BC033707.2 and AF070550.1. Transcript Variant: This variant (3) lacks an in-frame exon in the 5' coding region, compared to variant 1. It encodes isoform c which is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC033707.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGATGCCCT CGCCTAGTGA CTCCAGCCGC TCGCTGACCA GCCGGCCCAG CACCAGGGGC 
CTTACCCACC TCCGCCTCCA CCGACCCTGG CTGCAGGCCC TGCTTACGCT GGGGCTGGTC 
CAAGTGCTCC TGGGCATCCT GGTGGTCACC TTCAGCATGG TGGCCTCTTC CGTCACCACC 
ACCGAGAGCA TCAAGAGGTC CTGCCCGTCT TGGGCTGGGT TCTCGATCTC CTTCTTCTCC 
TTGCTTTCGG TGCTCTGTGT CATGCTTAGC ATGGCTGGCT CTGTTCTCTC CTGTAAGAAT 
GCTCAACTGG CCCGAGACTT CCAACAGTGC TCTCTGGAAG GAAAGGTCTG TGTGTGCTGT 
CCCTCTGTTC CCCTCCTCCG GCCCTGTCCA GAGTCGGGGC AGGAACTGAA AGTTGCCCCT 
AACTCCACCT GTGATGAAGC CCGAGGGGCC CTCAAGAACC TGCTCTTCAG CGTCTGTGGG 
CTCACCATTT GTGCCGCTAT AATCTGTACA CTCTCTGCTA TTGTCTGCTG CATCCAAATC 
TTCTCCCTGG ACCTCGTGCA TACGCAGCTG GCCCCTGAGC GGTCAGTCTC AGGCCCACTG 
GGACCTCTGG GCTGCACGTC CCCGCCCCCA GCCCCTCTCC TACACACCAT GCTGGACCTG 
GAGGAATTTG TCCCGCCTGT GCCCCCACCG CCCTACTATC CCCCAGAGTA TACCTGCAGC 
TCAGAAACAG ATGCACAGAG CATCACGTAC AATGGCTCCA TGGACAGCCC AGTGCCCTTG 
TACCCTACCG ATTGCCCCCC TTCTTATGAG GCAGTCATGG GACTACGAGG AGACAGCCAG 
GCCACTCTCT TTGACCCTCA GCTTCACGAT GGCTCGTGCA TCTGTGAACG AGTGGCCTCC 
ATTGTAGACG TGTCCATGGA CAGCGGGTCT CTGGTGCTGT CAGCCATTGG TGACCTCCCT 
GGGGGCTCTA GCCCGTCGGA GGACTCGTGC CTGCTGGAGC TGCAGGGCTC CGTGCGCTCC 
GTGGACTACG TTCTCTTTCG CTCCATCCAG CGCAGCCGTG CCGGCTACTG CCTCAGCCTG 
GACTGTGGCC TGCGGGGCCC CTTCGAGGAA AGCCCCCTGC CACGGCGCCC CCCACGGGCT 
GCCCGCTCCT ATTCCTGCTC TGCCCCTGAA GCTCCACCCC CACTGGGTGC CCCCACAGCT 
GCCCGCAGCT GCCACCGGTT GGAGGGCTGG CCGCCCTGGG TGGGACCCTG CTTCCCCGAG 
CTGAGGCGGC GGGTCCCCCG GGGAGGGGGC CGCCCAGCCG CAGCCCCGCC CACCCGAGCC 
CCGACTCGTC GCTTCAGCGA TAGCTCAGGT TCCCTCACCC CACCGGGGCA CCGGCCTCCT 
CATCCGGCAT CCCCACCACC GCTGCTGCTG CCACGGTCCC ACAGCGACCC AGGCATCACG 
ACCTCCAGTG ACACTGCTGA CTTCAGGGAC CTTTATACCA AAGTGCTTGA GGAAGAAGCT 
GCTTCTGTTT CCTCTGCAGA TACAGGGCTC TGCTCTGAAG CCTGCCTCTT CCGCCTAGCC 
CGCTGCCCTT CCCCCAAGTT GCTACGTGCC CGGTCAGCCG AGAAACGGCG CCCTGTGCCC 
ACCTTCCAAA AAGTTCCCCT GCCCTCGGGC CCTGCACCTG CCCACTCCCT GGGGGACCTA 
AAGGGCAGCT GGCCAGGTCG GGGCCTGGTC ACTCGTTTCC TCCAGATATC CAGGAAAGCC 
CCAGACCCCA GTGGGACTGG AGCTCATGGA CATAAGCAGG TGCCCCGGAG CCTGTGGGGC 
CGGCCTGGCC GAGAGAGCCT CCACCTTCGC AGCTGCGGAG ATCTGAGCTC TAGCTCTTCC 
CTGCGGCGTC TCCTGTCTGG CCGCAGGCTG GAGCGTGGTA CCCGCCCCCA CAGCCTCAGC 
CTCAACGGGG GCAGCCGGGA GACTGGGCTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001254537.1
CDS	607..2559
Translation	MMPSPSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTTTESIKRSCPSWAGFSISFFSLLSVLCVMLSMAGSVLSCKNAQLARDFQQCSLEGKVCVCCPSVPLLRPCPESGQELKVAPNSTCDEARGALKNLLFSVCGLTICAAIICTLSAIVCCIQIFSLDLVHTQLAPERSVSGPLGPLGCTSPPPAPLLHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPSYEAVMGLRGDSQATLFDPQLHDGSCICERVASIVDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQRSRAGYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLPRSHSDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPKLLRARSAEKRRPVPTFQKVPLPSGPAPAHSLGDLKGSWPGRGLVTRFLQISRKAPDPSGTGAHGHKQVPRSLWGRPGRESLHLRSCGDLSSSSSLRRLLSGRRLERGTRPHSLSLNGGSRETGL

Target ORF information:

RefSeq Version	NM_001267608.1
Organism	Homo sapiens(human)
Definition	Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267608.1

ORF Insert Sequence:

ATGATGCCCT CGCCTAGTGA CTCCAGCCGC TCGCTGACCA GCCGGCCCAG CACCAGGGGC 
CTTACCCACC TCCGCCTCCA CCGACCCTGG CTGCAGGCCC TGCTTACGCT GGGGCTGGTC 
CAAGTGCTCC TGGGCATCCT GGTGGTCACC TTCAGCATGG TGGCCTCTTC CGTCACCACC 
ACCGAGAGCA TCAAGAGGTC CTGCCCGTCT TGGGCTGGGT TCTCGATCTC CTTCTTCTCC 
TTGCTTTCGG TGCTCTGTGT CATGCTTAGC ATGGCTGGCT CTGTTCTCTC CTGTAAGAAT 
GCTCAACTGG CCCGAGACTT CCAACAGTGC TCTCTGGAAG GAAAGGTCTG TGTGTGCTGT 
CCCTCTGTTC CCCTCCTCCG GCCCTGTCCA GAGTCGGGGC AGGAACTGAA AGTTGCCCCT 
AACTCCACCT GTGATGAAGC CCGAGGGGCC CTCAAGAACC TGCTCTTCAG CGTCTGTGGG 
CTCACCATTT GTGCCGCTAT AATCTGTACA CTCTCTGCTA TTGTCTGCTG CATCCAAATC 
TTCTCCCTGG ACCTCGTGCA TACGCAGCTG GCCCCTGAGC GGTCAGTCTC AGGCCCACTG 
GGACCTCTGG GCTGCACGTC CCCGCCCCCA GCCCCTCTCC TACACACCAT GCTGGACCTG 
GAGGAATTTG TCCCGCCTGT GCCCCCACCG CCCTACTATC CCCCAGAGTA TACCTGCAGC 
TCAGAAACAG ATGCACAGAG CATCACGTAC AATGGCTCCA TGGACAGCCC AGTGCCCTTG 
TACCCTACCG ATTGCCCCCC TTCTTATGAG GCAGTCATGG GACTACGAGG AGACAGCCAG 
GCCACTCTCT TTGACCCTCA GCTTCACGAT GGCTCGTGCA TCTGTGAACG AGTGGCCTCC 
ATTGTAGACG TGTCCATGGA CAGCGGGTCT CTGGTGCTGT CAGCCATTGG TGACCTCCCT 
GGGGGCTCTA GCCCGTCGGA GGACTCGTGC CTGCTGGAGC TGCAGGGCTC CGTGCGCTCC 
GTGGACTACG TTCTCTTTCG CTCCATCCAG CGCAGCCGTG CCGGCTACTG CCTCAGCCTG 
GACTGTGGCC TGCGGGGCCC CTTCGAGGAA AGCCCCCTGC CACGGCGCCC CCCACGGGCT 
GCCCGCTCCT ATTCCTGCTC TGCCCCTGAA GCTCCACCCC CACTGGGTGC CCCCACAGCT 
GCCCGCAGCT GCCACCGGTT GGAGGGCTGG CCGCCCTGGG TGGGACCCTG CTTCCCCGAG 
CTGAGGCGGC GGGTCCCCCG GGGAGGGGGC CGCCCAGCCG CAGCCCCGCC CACCCGAGCC 
CCGACTCGTC GCTTCAGCGA TAGCTCAGGT TCCCTCACCC CACCGGGGCA CCGGCCTCCT 
CATCCGGCAT CCCCACCACC GCTGCTGCTG CCACGGTCCC ACAGCGACCC AGGCATCACG 
ACCTCCAGTG ACACTGCTGA CTTCAGGGAC CTTTATACCA AAGTGCTTGA GGAAGAAGCT 
GCTTCTGTTT CCTCTGCAGA TACAGGGCTC TGCTCTGAAG CCTGCCTCTT CCGCCTAGCC 
CGCTGCCCTT CCCCCAAGTT GCTACGTGCC CGGTCAGCCG AGAAACGGCG CCCTGTGCCC 
ACCTTCCAAA AAGTTCCCCT GCCCTCGGGC CCTGCACCTG CCCACTCCCT GGGGGACCTA 
AAGGGCAGCT GGCCAGGTCG GGGCCTGGTC ACTCGTTTCC TCCAGATATC CAGGAAAGCC 
CCAGACCCCA GTGGGACTGG AGCTCATGGA CATAAGCAGG TGCCCCGGAG CCTGTGGGGC 
CGGCCTGGCC GAGAGAGCCT CCACCTTCGC AGCTGCGGAG ATCTGAGCTC TAGCTCTTCC 
CTGCGGCGTC TCCTGTCTGG CCGCAGGCTG GAGCGTGGTA CCCGCCCCCA CAGCCTCAGC 
CTCAACGGGG GCAGCCGGGA GACTGGGCTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FAM189B ( NM_001267608.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001254537.1 Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant 3, mRNA.

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CloneID	OHu11445
Clone ID Related Accession (Same CDS sequence)	NM_001267608.1 , NM_001267608.2
Accession Version	NM_001267608.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1953bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	protein FAM189B isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL713999.28, BC033707.2 and AF070550.1. On May 31, 2019 this sequence version replaced NM_001267608.1. Transcript Variant: This variant (3) lacks an in-frame exon in the 5' coding region, compared to variant 1. It encodes isoform c which is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC033707.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGATGCCCT CGCCTAGTGA CTCCAGCCGC TCGCTGACCA GCCGGCCCAG CACCAGGGGC 
CTTACCCACC TCCGCCTCCA CCGACCCTGG CTGCAGGCCC TGCTTACGCT GGGGCTGGTC 
CAAGTGCTCC TGGGCATCCT GGTGGTCACC TTCAGCATGG TGGCCTCTTC CGTCACCACC 
ACCGAGAGCA TCAAGAGGTC CTGCCCGTCT TGGGCTGGGT TCTCGATCTC CTTCTTCTCC 
TTGCTTTCGG TGCTCTGTGT CATGCTTAGC ATGGCTGGCT CTGTTCTCTC CTGTAAGAAT 
GCTCAACTGG CCCGAGACTT CCAACAGTGC TCTCTGGAAG GAAAGGTCTG TGTGTGCTGT 
CCCTCTGTTC CCCTCCTCCG GCCCTGTCCA GAGTCGGGGC AGGAACTGAA AGTTGCCCCT 
AACTCCACCT GTGATGAAGC CCGAGGGGCC CTCAAGAACC TGCTCTTCAG CGTCTGTGGG 
CTCACCATTT GTGCCGCTAT AATCTGTACA CTCTCTGCTA TTGTCTGCTG CATCCAAATC 
TTCTCCCTGG ACCTCGTGCA TACGCAGCTG GCCCCTGAGC GGTCAGTCTC AGGCCCACTG 
GGACCTCTGG GCTGCACGTC CCCGCCCCCA GCCCCTCTCC TACACACCAT GCTGGACCTG 
GAGGAATTTG TCCCGCCTGT GCCCCCACCG CCCTACTATC CCCCAGAGTA TACCTGCAGC 
TCAGAAACAG ATGCACAGAG CATCACGTAC AATGGCTCCA TGGACAGCCC AGTGCCCTTG 
TACCCTACCG ATTGCCCCCC TTCTTATGAG GCAGTCATGG GACTACGAGG AGACAGCCAG 
GCCACTCTCT TTGACCCTCA GCTTCACGAT GGCTCGTGCA TCTGTGAACG AGTGGCCTCC 
ATTGTAGACG TGTCCATGGA CAGCGGGTCT CTGGTGCTGT CAGCCATTGG TGACCTCCCT 
GGGGGCTCTA GCCCGTCGGA GGACTCGTGC CTGCTGGAGC TGCAGGGCTC CGTGCGCTCC 
GTGGACTACG TTCTCTTTCG CTCCATCCAG CGCAGCCGTG CCGGCTACTG CCTCAGCCTG 
GACTGTGGCC TGCGGGGCCC CTTCGAGGAA AGCCCCCTGC CACGGCGCCC CCCACGGGCT 
GCCCGCTCCT ATTCCTGCTC TGCCCCTGAA GCTCCACCCC CACTGGGTGC CCCCACAGCT 
GCCCGCAGCT GCCACCGGTT GGAGGGCTGG CCGCCCTGGG TGGGACCCTG CTTCCCCGAG 
CTGAGGCGGC GGGTCCCCCG GGGAGGGGGC CGCCCAGCCG CAGCCCCGCC CACCCGAGCC 
CCGACTCGTC GCTTCAGCGA TAGCTCAGGT TCCCTCACCC CACCGGGGCA CCGGCCTCCT 
CATCCGGCAT CCCCACCACC GCTGCTGCTG CCACGGTCCC ACAGCGACCC AGGCATCACG 
ACCTCCAGTG ACACTGCTGA CTTCAGGGAC CTTTATACCA AAGTGCTTGA GGAAGAAGCT 
GCTTCTGTTT CCTCTGCAGA TACAGGGCTC TGCTCTGAAG CCTGCCTCTT CCGCCTAGCC 
CGCTGCCCTT CCCCCAAGTT GCTACGTGCC CGGTCAGCCG AGAAACGGCG CCCTGTGCCC 
ACCTTCCAAA AAGTTCCCCT GCCCTCGGGC CCTGCACCTG CCCACTCCCT GGGGGACCTA 
AAGGGCAGCT GGCCAGGTCG GGGCCTGGTC ACTCGTTTCC TCCAGATATC CAGGAAAGCC 
CCAGACCCCA GTGGGACTGG AGCTCATGGA CATAAGCAGG TGCCCCGGAG CCTGTGGGGC 
CGGCCTGGCC GAGAGAGCCT CCACCTTCGC AGCTGCGGAG ATCTGAGCTC TAGCTCTTCC 
CTGCGGCGTC TCCTGTCTGG CCGCAGGCTG GAGCGTGGTA CCCGCCCCCA CAGCCTCAGC 
CTCAACGGGG GCAGCCGGGA GACTGGGCTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001254537.1
CDS	607..2559
Translation	MMPSPSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTTTESIKRSCPSWAGFSISFFSLLSVLCVMLSMAGSVLSCKNAQLARDFQQCSLEGKVCVCCPSVPLLRPCPESGQELKVAPNSTCDEARGALKNLLFSVCGLTICAAIICTLSAIVCCIQIFSLDLVHTQLAPERSVSGPLGPLGCTSPPPAPLLHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPSYEAVMGLRGDSQATLFDPQLHDGSCICERVASIVDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQRSRAGYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLPRSHSDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPKLLRARSAEKRRPVPTFQKVPLPSGPAPAHSLGDLKGSWPGRGLVTRFLQISRKAPDPSGTGAHGHKQVPRSLWGRPGRESLHLRSCGDLSSSSSLRRLLSGRRLERGTRPHSLSLNGGSRETGL

Target ORF information:

RefSeq Version	NM_001267608.2
Organism	Homo sapiens(human)
Definition	Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267608.2

ORF Insert Sequence:

ATGATGCCCT CGCCTAGTGA CTCCAGCCGC TCGCTGACCA GCCGGCCCAG CACCAGGGGC 
CTTACCCACC TCCGCCTCCA CCGACCCTGG CTGCAGGCCC TGCTTACGCT GGGGCTGGTC 
CAAGTGCTCC TGGGCATCCT GGTGGTCACC TTCAGCATGG TGGCCTCTTC CGTCACCACC 
ACCGAGAGCA TCAAGAGGTC CTGCCCGTCT TGGGCTGGGT TCTCGATCTC CTTCTTCTCC 
TTGCTTTCGG TGCTCTGTGT CATGCTTAGC ATGGCTGGCT CTGTTCTCTC CTGTAAGAAT 
GCTCAACTGG CCCGAGACTT CCAACAGTGC TCTCTGGAAG GAAAGGTCTG TGTGTGCTGT 
CCCTCTGTTC CCCTCCTCCG GCCCTGTCCA GAGTCGGGGC AGGAACTGAA AGTTGCCCCT 
AACTCCACCT GTGATGAAGC CCGAGGGGCC CTCAAGAACC TGCTCTTCAG CGTCTGTGGG 
CTCACCATTT GTGCCGCTAT AATCTGTACA CTCTCTGCTA TTGTCTGCTG CATCCAAATC 
TTCTCCCTGG ACCTCGTGCA TACGCAGCTG GCCCCTGAGC GGTCAGTCTC AGGCCCACTG 
GGACCTCTGG GCTGCACGTC CCCGCCCCCA GCCCCTCTCC TACACACCAT GCTGGACCTG 
GAGGAATTTG TCCCGCCTGT GCCCCCACCG CCCTACTATC CCCCAGAGTA TACCTGCAGC 
TCAGAAACAG ATGCACAGAG CATCACGTAC AATGGCTCCA TGGACAGCCC AGTGCCCTTG 
TACCCTACCG ATTGCCCCCC TTCTTATGAG GCAGTCATGG GACTACGAGG AGACAGCCAG 
GCCACTCTCT TTGACCCTCA GCTTCACGAT GGCTCGTGCA TCTGTGAACG AGTGGCCTCC 
ATTGTAGACG TGTCCATGGA CAGCGGGTCT CTGGTGCTGT CAGCCATTGG TGACCTCCCT 
GGGGGCTCTA GCCCGTCGGA GGACTCGTGC CTGCTGGAGC TGCAGGGCTC CGTGCGCTCC 
GTGGACTACG TTCTCTTTCG CTCCATCCAG CGCAGCCGTG CCGGCTACTG CCTCAGCCTG 
GACTGTGGCC TGCGGGGCCC CTTCGAGGAA AGCCCCCTGC CACGGCGCCC CCCACGGGCT 
GCCCGCTCCT ATTCCTGCTC TGCCCCTGAA GCTCCACCCC CACTGGGTGC CCCCACAGCT 
GCCCGCAGCT GCCACCGGTT GGAGGGCTGG CCGCCCTGGG TGGGACCCTG CTTCCCCGAG 
CTGAGGCGGC GGGTCCCCCG GGGAGGGGGC CGCCCAGCCG CAGCCCCGCC CACCCGAGCC 
CCGACTCGTC GCTTCAGCGA TAGCTCAGGT TCCCTCACCC CACCGGGGCA CCGGCCTCCT 
CATCCGGCAT CCCCACCACC GCTGCTGCTG CCACGGTCCC ACAGCGACCC AGGCATCACG 
ACCTCCAGTG ACACTGCTGA CTTCAGGGAC CTTTATACCA AAGTGCTTGA GGAAGAAGCT 
GCTTCTGTTT CCTCTGCAGA TACAGGGCTC TGCTCTGAAG CCTGCCTCTT CCGCCTAGCC 
CGCTGCCCTT CCCCCAAGTT GCTACGTGCC CGGTCAGCCG AGAAACGGCG CCCTGTGCCC 
ACCTTCCAAA AAGTTCCCCT GCCCTCGGGC CCTGCACCTG CCCACTCCCT GGGGGACCTA 
AAGGGCAGCT GGCCAGGTCG GGGCCTGGTC ACTCGTTTCC TCCAGATATC CAGGAAAGCC 
CCAGACCCCA GTGGGACTGG AGCTCATGGA CATAAGCAGG TGCCCCGGAG CCTGTGGGGC 
CGGCCTGGCC GAGAGAGCCT CCACCTTCGC AGCTGCGGAG ATCTGAGCTC TAGCTCTTCC 
CTGCGGCGTC TCCTGTCTGG CCGCAGGCTG GAGCGTGGTA CCCGCCCCCA CAGCCTCAGC 
CTCAACGGGG GCAGCCGGGA GACTGGGCTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FAM189B ( XM_005244845.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005244902.1 Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu34080
Clone ID Related Accession (Same CDS sequence)	XM_005244845.1 , XM_005244845.2
Accession Version	XM_005244845.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2010bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	protein FAM189B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGCCCT CGCCTAGTGA CTCCAGCCGC TCGCTGACCA GCCGGCCCAG CACCAGGGGC 
CTTACCCACC TCCGCCTCCA CCGACCCTGG CTGCAGGCCC TGCTTACGCT GGGGCTGGTC 
CAAGTGCTCC TGGGCATCCT GGTGGTCACC TTCAGCATGG TGGCCTCTTC CGTCACCACC 
ACCGAGAGCA TCAAGAGGTC CTGCCCGTCT TGGGCTGGGT TCTCGCTGGC GTTCTCCGGG 
GTGGTTGGCA TTGTGTCCTG GAAGCGGCCA TTCACTCTAG TGATCTCCTT CTTCTCCTTG 
CTTTCGGTGC TCTGTGTCAT GCTTAGCATG GCTGGCTCTG TTCTCTCCTG TAAGAATGCT 
CAACTGGCCC GAGACTTCCA ACAGTGCTCT CTGGAAGGAA AGGTCTGTGT GTGCTGTCCC 
TCTGTTCCCC TCCTCCGGCC CTGTCCAGAG TCGGGGCAGG AACTGAAAGT TGCCCCTAAC 
TCCACCTGTG ATGAAGCCCG AGGGGCCCTC AAGAACCTGC TCTTCAGCGT CTGTGGGCTC 
ACCATTTGTG CCGCTATAAT CTGTACACTC TCTGCTATTG TCTGCTGCAT CCAAATCTTC 
TCCCTGGACC TCGTGCATAC GCAGCTGGCC CCTGAGCGGT CAGTCTCAGG CCCACTGGGA 
CCTCTGGGCT GCACGTCCCC GCCCCCAGCC CCTCTCCTAC ACACCATGCT GGACCTGGAG 
GAATTTGTCC CGCCTGTGCC CCCACCGCCC TACTATCCCC CAGAGTATAC CTGCAGCTCA 
GAAACAGATG CACAGAGCAT CACGTACAAT GGCTCCATGG ACAGCCCAGT GCCCTTGTAC 
CCTACCGATT GCCCCCCTTC TTATGAGGCA GTCATGGGAC TACGAGGAGA CAGCCAGGCC 
ACTCTCTTTG ACCCTCAGCT TCACGATGGC TCGTGCATCT GTGAACGAGT GGCCTCCATT 
GTAGACGTGT CCATGGACAG CGGGTCTCTG GTGCTGTCAG CCATTGGTGA CCTCCCTGGG 
GGCTCTAGCC CGTCGGAGGA CTCGTGCCTG CTGGAGCTGC AGGGCTCCGT GCGCTCCGTG 
GACTACGTTC TCTTTCGCTC CATCCAGCGC AGCCGTGCCG GCTACTGCCT CAGCCTGGAC 
TGTGGCCTGC GGGGCCCCTT CGAGGAAAGC CCCCTGCCAC GGCGCCCCCC ACGGGCTGCC 
CGCTCCTATT CCTGCTCTGC CCCTGAAGCT CCACCCCCAC TGGGTGCCCC CACAGCTGCC 
CGCAGCTGCC ACCGGTTGGA GGGCTGGCCG CCCTGGGTGG GACCCTGCTT CCCCGAGCTG 
AGGCGGCGGG TCCCCCGGGG AGGGGGCCGC CCAGCCGCAG CCCCGCCCAC CCGAGCCCCG 
ACTCGTCGCT TCAGCGATAG CTCAGGTTCC CTCACCCCAC CGGGGCACCG GCCTCCTCAT 
CCGGCATCCC CACCACCGCT GCTGCTGCCA CGGTCCCACA GCGACCCAGG CATCACGACC 
TCCAGTGACA CTGCTGACTT CAGGGACCTT TATACCAAAG TGCTTGAGGA AGAAGCTGCT 
TCTGTTTCCT CTGCAGATAC AGGGCTCTGC TCTGAAGCCT GCCTCTTCCG CCTAGCCCGC 
TGCCCTTCCC CCAAGTTGCT ACGTGCCCGG TCAGCCGAGA AACGGCGCCC TGTGCCCACC 
TTCCAAAAAG TTCCCCTGCC CTCGGGCCCT GCACCTGCCC ACTCCCTGGG GGACCTAAAG 
GGCAGCTGGC CAGGTCGGGG CCTGGTCACT CGTTTCCTCC AGATATCCAG GAAAGCCCCA 
GACCCCAGTG GGACTGGAGC TCATGGACAT AAGCAGGTGC CCCGGAGCCT GTGGGGCCGG 
CCTGGCCGAG AGAGCCTCCA CCTTCGCAGC TGCGGAGATC TGAGCTCTAG CTCTTCCCTG 
CGGCGTCTCC TGTCTGGCCG CAGGCTGGAG CGTGGTACCC GCCCCCACAG CCTCAGCCTC 
AACGGGGGCA GCCGGGAGAC TGGGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005244902.1
CDS	601..2610
Translation	MMPSPSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTTTESIKRSCPSWAGFSLAFSGVVGIVSWKRPFTLVISFFSLLSVLCVMLSMAGSVLSCKNAQLARDFQQCSLEGKVCVCCPSVPLLRPCPESGQELKVAPNSTCDEARGALKNLLFSVCGLTICAAIICTLSAIVCCIQIFSLDLVHTQLAPERSVSGPLGPLGCTSPPPAPLLHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPSYEAVMGLRGDSQATLFDPQLHDGSCICERVASIVDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQRSRAGYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLPRSHSDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPKLLRARSAEKRRPVPTFQKVPLPSGPAPAHSLGDLKGSWPGRGLVTRFLQISRKAPDPSGTGAHGHKQVPRSLWGRPGRESLHLRSCGDLSSSSSLRRLLSGRRLERGTRPHSLSLNGGSRETGL

Target ORF information:

RefSeq Version	XM_005244845.1
Organism	Homo sapiens(human)
Definition	Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005244845.1

ORF Insert Sequence:

ATGATGCCCT CGCCTAGTGA CTCCAGCCGC TCGCTGACCA GCCGGCCCAG CACCAGGGGC 
CTTACCCACC TCCGCCTCCA CCGACCCTGG CTGCAGGCCC TGCTTACGCT GGGGCTGGTC 
CAAGTGCTCC TGGGCATCCT GGTGGTCACC TTCAGCATGG TGGCCTCTTC CGTCACCACC 
ACCGAGAGCA TCAAGAGGTC CTGCCCGTCT TGGGCTGGGT TCTCGCTGGC GTTCTCCGGG 
GTGGTTGGCA TTGTGTCCTG GAAGCGGCCA TTCACTCTAG TGATCTCCTT CTTCTCCTTG 
CTTTCGGTGC TCTGTGTCAT GCTTAGCATG GCTGGCTCTG TTCTCTCCTG TAAGAATGCT 
CAACTGGCCC GAGACTTCCA ACAGTGCTCT CTGGAAGGAA AGGTCTGTGT GTGCTGTCCC 
TCTGTTCCCC TCCTCCGGCC CTGTCCAGAG TCGGGGCAGG AACTGAAAGT TGCCCCTAAC 
TCCACCTGTG ATGAAGCCCG AGGGGCCCTC AAGAACCTGC TCTTCAGCGT CTGTGGGCTC 
ACCATTTGTG CCGCTATAAT CTGTACACTC TCTGCTATTG TCTGCTGCAT CCAAATCTTC 
TCCCTGGACC TCGTGCATAC GCAGCTGGCC CCTGAGCGGT CAGTCTCAGG CCCACTGGGA 
CCTCTGGGCT GCACGTCCCC GCCCCCAGCC CCTCTCCTAC ACACCATGCT GGACCTGGAG 
GAATTTGTCC CGCCTGTGCC CCCACCGCCC TACTATCCCC CAGAGTATAC CTGCAGCTCA 
GAAACAGATG CACAGAGCAT CACGTACAAT GGCTCCATGG ACAGCCCAGT GCCCTTGTAC 
CCTACCGATT GCCCCCCTTC TTATGAGGCA GTCATGGGAC TACGAGGAGA CAGCCAGGCC 
ACTCTCTTTG ACCCTCAGCT TCACGATGGC TCGTGCATCT GTGAACGAGT GGCCTCCATT 
GTAGACGTGT CCATGGACAG CGGGTCTCTG GTGCTGTCAG CCATTGGTGA CCTCCCTGGG 
GGCTCTAGCC CGTCGGAGGA CTCGTGCCTG CTGGAGCTGC AGGGCTCCGT GCGCTCCGTG 
GACTACGTTC TCTTTCGCTC CATCCAGCGC AGCCGTGCCG GCTACTGCCT CAGCCTGGAC 
TGTGGCCTGC GGGGCCCCTT CGAGGAAAGC CCCCTGCCAC GGCGCCCCCC ACGGGCTGCC 
CGCTCCTATT CCTGCTCTGC CCCTGAAGCT CCACCCCCAC TGGGTGCCCC CACAGCTGCC 
CGCAGCTGCC ACCGGTTGGA GGGCTGGCCG CCCTGGGTGG GACCCTGCTT CCCCGAGCTG 
AGGCGGCGGG TCCCCCGGGG AGGGGGCCGC CCAGCCGCAG CCCCGCCCAC CCGAGCCCCG 
ACTCGTCGCT TCAGCGATAG CTCAGGTTCC CTCACCCCAC CGGGGCACCG GCCTCCTCAT 
CCGGCATCCC CACCACCGCT GCTGCTGCCA CGGTCCCACA GCGACCCAGG CATCACGACC 
TCCAGTGACA CTGCTGACTT CAGGGACCTT TATACCAAAG TGCTTGAGGA AGAAGCTGCT 
TCTGTTTCCT CTGCAGATAC AGGGCTCTGC TCTGAAGCCT GCCTCTTCCG CCTAGCCCGC 
TGCCCTTCCC CCAAGTTGCT ACGTGCCCGG TCAGCCGAGA AACGGCGCCC TGTGCCCACC 
TTCCAAAAAG TTCCCCTGCC CTCGGGCCCT GCACCTGCCC ACTCCCTGGG GGACCTAAAG 
GGCAGCTGGC CAGGTCGGGG CCTGGTCACT CGTTTCCTCC AGATATCCAG GAAAGCCCCA 
GACCCCAGTG GGACTGGAGC TCATGGACAT AAGCAGGTGC CCCGGAGCCT GTGGGGCCGG 
CCTGGCCGAG AGAGCCTCCA CCTTCGCAGC TGCGGAGATC TGAGCTCTAG CTCTTCCCTG 
CGGCGTCTCC TGTCTGGCCG CAGGCTGGAG CGTGGTACCC GCCCCCACAG CCTCAGCCTC 
AACGGGGGCA GCCGGGAGAC TGGGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FAM189B ( XM_005244845.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005244902.1 Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu34080
Clone ID Related Accession (Same CDS sequence)	XM_005244845.1 , XM_005244845.2
Accession Version	XM_005244845.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2010bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein FAM189B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005244845.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGCCCT CGCCTAGTGA CTCCAGCCGC TCGCTGACCA GCCGGCCCAG CACCAGGGGC 
CTTACCCACC TCCGCCTCCA CCGACCCTGG CTGCAGGCCC TGCTTACGCT GGGGCTGGTC 
CAAGTGCTCC TGGGCATCCT GGTGGTCACC TTCAGCATGG TGGCCTCTTC CGTCACCACC 
ACCGAGAGCA TCAAGAGGTC CTGCCCGTCT TGGGCTGGGT TCTCGCTGGC GTTCTCCGGG 
GTGGTTGGCA TTGTGTCCTG GAAGCGGCCA TTCACTCTAG TGATCTCCTT CTTCTCCTTG 
CTTTCGGTGC TCTGTGTCAT GCTTAGCATG GCTGGCTCTG TTCTCTCCTG TAAGAATGCT 
CAACTGGCCC GAGACTTCCA ACAGTGCTCT CTGGAAGGAA AGGTCTGTGT GTGCTGTCCC 
TCTGTTCCCC TCCTCCGGCC CTGTCCAGAG TCGGGGCAGG AACTGAAAGT TGCCCCTAAC 
TCCACCTGTG ATGAAGCCCG AGGGGCCCTC AAGAACCTGC TCTTCAGCGT CTGTGGGCTC 
ACCATTTGTG CCGCTATAAT CTGTACACTC TCTGCTATTG TCTGCTGCAT CCAAATCTTC 
TCCCTGGACC TCGTGCATAC GCAGCTGGCC CCTGAGCGGT CAGTCTCAGG CCCACTGGGA 
CCTCTGGGCT GCACGTCCCC GCCCCCAGCC CCTCTCCTAC ACACCATGCT GGACCTGGAG 
GAATTTGTCC CGCCTGTGCC CCCACCGCCC TACTATCCCC CAGAGTATAC CTGCAGCTCA 
GAAACAGATG CACAGAGCAT CACGTACAAT GGCTCCATGG ACAGCCCAGT GCCCTTGTAC 
CCTACCGATT GCCCCCCTTC TTATGAGGCA GTCATGGGAC TACGAGGAGA CAGCCAGGCC 
ACTCTCTTTG ACCCTCAGCT TCACGATGGC TCGTGCATCT GTGAACGAGT GGCCTCCATT 
GTAGACGTGT CCATGGACAG CGGGTCTCTG GTGCTGTCAG CCATTGGTGA CCTCCCTGGG 
GGCTCTAGCC CGTCGGAGGA CTCGTGCCTG CTGGAGCTGC AGGGCTCCGT GCGCTCCGTG 
GACTACGTTC TCTTTCGCTC CATCCAGCGC AGCCGTGCCG GCTACTGCCT CAGCCTGGAC 
TGTGGCCTGC GGGGCCCCTT CGAGGAAAGC CCCCTGCCAC GGCGCCCCCC ACGGGCTGCC 
CGCTCCTATT CCTGCTCTGC CCCTGAAGCT CCACCCCCAC TGGGTGCCCC CACAGCTGCC 
CGCAGCTGCC ACCGGTTGGA GGGCTGGCCG CCCTGGGTGG GACCCTGCTT CCCCGAGCTG 
AGGCGGCGGG TCCCCCGGGG AGGGGGCCGC CCAGCCGCAG CCCCGCCCAC CCGAGCCCCG 
ACTCGTCGCT TCAGCGATAG CTCAGGTTCC CTCACCCCAC CGGGGCACCG GCCTCCTCAT 
CCGGCATCCC CACCACCGCT GCTGCTGCCA CGGTCCCACA GCGACCCAGG CATCACGACC 
TCCAGTGACA CTGCTGACTT CAGGGACCTT TATACCAAAG TGCTTGAGGA AGAAGCTGCT 
TCTGTTTCCT CTGCAGATAC AGGGCTCTGC TCTGAAGCCT GCCTCTTCCG CCTAGCCCGC 
TGCCCTTCCC CCAAGTTGCT ACGTGCCCGG TCAGCCGAGA AACGGCGCCC TGTGCCCACC 
TTCCAAAAAG TTCCCCTGCC CTCGGGCCCT GCACCTGCCC ACTCCCTGGG GGACCTAAAG 
GGCAGCTGGC CAGGTCGGGG CCTGGTCACT CGTTTCCTCC AGATATCCAG GAAAGCCCCA 
GACCCCAGTG GGACTGGAGC TCATGGACAT AAGCAGGTGC CCCGGAGCCT GTGGGGCCGG 
CCTGGCCGAG AGAGCCTCCA CCTTCGCAGC TGCGGAGATC TGAGCTCTAG CTCTTCCCTG 
CGGCGTCTCC TGTCTGGCCG CAGGCTGGAG CGTGGTACCC GCCCCCACAG CCTCAGCCTC 
AACGGGGGCA GCCGGGAGAC TGGGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005244902.1
CDS	1016..3025
Translation	MMPSPSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTTTESIKRSCPSWAGFSLAFSGVVGIVSWKRPFTLVISFFSLLSVLCVMLSMAGSVLSCKNAQLARDFQQCSLEGKVCVCCPSVPLLRPCPESGQELKVAPNSTCDEARGALKNLLFSVCGLTICAAIICTLSAIVCCIQIFSLDLVHTQLAPERSVSGPLGPLGCTSPPPAPLLHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPSYEAVMGLRGDSQATLFDPQLHDGSCICERVASIVDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQRSRAGYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAPEAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRRVPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHPASPPPLLLPRSHSDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPKLLRARSAEKRRPVPTFQKVPLPSGPAPAHSLGDLKGSWPGRGLVTRFLQISRKAPDPSGTGAHGHKQVPRSLWGRPGRESLHLRSCGDLSSSSSLRRLLSGRRLERGTRPHSLSLNGGSRETGL

Target ORF information:

RefSeq Version	XM_005244845.2
Organism	Homo sapiens(human)
Definition	Homo sapiens family with sequence similarity 189 member B (FAM189B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005244845.2

ORF Insert Sequence:

ATGATGCCCT CGCCTAGTGA CTCCAGCCGC TCGCTGACCA GCCGGCCCAG CACCAGGGGC 
CTTACCCACC TCCGCCTCCA CCGACCCTGG CTGCAGGCCC TGCTTACGCT GGGGCTGGTC 
CAAGTGCTCC TGGGCATCCT GGTGGTCACC TTCAGCATGG TGGCCTCTTC CGTCACCACC 
ACCGAGAGCA TCAAGAGGTC CTGCCCGTCT TGGGCTGGGT TCTCGCTGGC GTTCTCCGGG 
GTGGTTGGCA TTGTGTCCTG GAAGCGGCCA TTCACTCTAG TGATCTCCTT CTTCTCCTTG 
CTTTCGGTGC TCTGTGTCAT GCTTAGCATG GCTGGCTCTG TTCTCTCCTG TAAGAATGCT 
CAACTGGCCC GAGACTTCCA ACAGTGCTCT CTGGAAGGAA AGGTCTGTGT GTGCTGTCCC 
TCTGTTCCCC TCCTCCGGCC CTGTCCAGAG TCGGGGCAGG AACTGAAAGT TGCCCCTAAC 
TCCACCTGTG ATGAAGCCCG AGGGGCCCTC AAGAACCTGC TCTTCAGCGT CTGTGGGCTC 
ACCATTTGTG CCGCTATAAT CTGTACACTC TCTGCTATTG TCTGCTGCAT CCAAATCTTC 
TCCCTGGACC TCGTGCATAC GCAGCTGGCC CCTGAGCGGT CAGTCTCAGG CCCACTGGGA 
CCTCTGGGCT GCACGTCCCC GCCCCCAGCC CCTCTCCTAC ACACCATGCT GGACCTGGAG 
GAATTTGTCC CGCCTGTGCC CCCACCGCCC TACTATCCCC CAGAGTATAC CTGCAGCTCA 
GAAACAGATG CACAGAGCAT CACGTACAAT GGCTCCATGG ACAGCCCAGT GCCCTTGTAC 
CCTACCGATT GCCCCCCTTC TTATGAGGCA GTCATGGGAC TACGAGGAGA CAGCCAGGCC 
ACTCTCTTTG ACCCTCAGCT TCACGATGGC TCGTGCATCT GTGAACGAGT GGCCTCCATT 
GTAGACGTGT CCATGGACAG CGGGTCTCTG GTGCTGTCAG CCATTGGTGA CCTCCCTGGG 
GGCTCTAGCC CGTCGGAGGA CTCGTGCCTG CTGGAGCTGC AGGGCTCCGT GCGCTCCGTG 
GACTACGTTC TCTTTCGCTC CATCCAGCGC AGCCGTGCCG GCTACTGCCT CAGCCTGGAC 
TGTGGCCTGC GGGGCCCCTT CGAGGAAAGC CCCCTGCCAC GGCGCCCCCC ACGGGCTGCC 
CGCTCCTATT CCTGCTCTGC CCCTGAAGCT CCACCCCCAC TGGGTGCCCC CACAGCTGCC 
CGCAGCTGCC ACCGGTTGGA GGGCTGGCCG CCCTGGGTGG GACCCTGCTT CCCCGAGCTG 
AGGCGGCGGG TCCCCCGGGG AGGGGGCCGC CCAGCCGCAG CCCCGCCCAC CCGAGCCCCG 
ACTCGTCGCT TCAGCGATAG CTCAGGTTCC CTCACCCCAC CGGGGCACCG GCCTCCTCAT 
CCGGCATCCC CACCACCGCT GCTGCTGCCA CGGTCCCACA GCGACCCAGG CATCACGACC 
TCCAGTGACA CTGCTGACTT CAGGGACCTT TATACCAAAG TGCTTGAGGA AGAAGCTGCT 
TCTGTTTCCT CTGCAGATAC AGGGCTCTGC TCTGAAGCCT GCCTCTTCCG CCTAGCCCGC 
TGCCCTTCCC CCAAGTTGCT ACGTGCCCGG TCAGCCGAGA AACGGCGCCC TGTGCCCACC 
TTCCAAAAAG TTCCCCTGCC CTCGGGCCCT GCACCTGCCC ACTCCCTGGG GGACCTAAAG 
GGCAGCTGGC CAGGTCGGGG CCTGGTCACT CGTTTCCTCC AGATATCCAG GAAAGCCCCA 
GACCCCAGTG GGACTGGAGC TCATGGACAT AAGCAGGTGC CCCGGAGCCT GTGGGGCCGG 
CCTGGCCGAG AGAGCCTCCA CCTTCGCAGC TGCGGAGATC TGAGCTCTAG CTCTTCCCTG 
CGGCGTCTCC TGTCTGGCCG CAGGCTGGAG CGTGGTACCC GCCCCCACAG CCTCAGCCTC 
AACGGGGGCA GCCGGGAGAC TGGGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Upregulation of the putative oncogene COTE1 contributes to human hepatocarcinogenesis through modulation of WWOX signaling.
International journal of oncology45(2)719-31(2014 Aug)
Zhang H,Tian Y,Shen J,Wang Y,Xu Y,Wang Y,Han Z,Li X

Ectopic overexpression of COTE1 promotes cellular invasion of hepatocellular carcinoma.
Asian Pacific journal of cancer prevention : APJCP13(11)5799-804(2012)
Zhang H,Huang CJ,Tian Y,Wang YP,Han ZG,Li XC

SREBP-1 regulates the expression of heme oxygenase 1 and the phosphatidylinositol-3 kinase regulatory subunit p55 gamma.
Journal of lipid research48(7)1628-36(2007 Jul)
Kallin A,Johannessen LE,Cani PD,Marbehant CY,Essaghir A,Foufelle F,Ferr? P,Heldin CH,Delzenne NM,Demoulin JB

WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins.
Oncogene23(29)5049-55(2004 Jun)
Ludes-Meyers JH,Kil H,Bednarek AK,Drake J,Bedford MT,Aldaz CM

Identification of three additional genes contiguous to the glucocerebrosidase locus on chromosome 1q21: implications for Gaucher disease.
Genome research7(10)1020-6(1997 Oct)
Winfield SL,Tayebi N,Martin BM,Ginns EI,Sidransky E

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FAM189B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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