IPO8 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	IPO8
Entrez Gene ID	10526
Full Name	importin 8
Synonyms	RANBP8
General protein information	Preferred Names importin 8 Names importin-8 RAN binding protein 8 imp8 ran-binding protein 8
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12p11.21
Summary	The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
Disorder MIM:	605600

mRNA and Protein(s)

mRNA	Protein	Name
XM_017018693.1	XP_016874182.1	importin-8 isoform X3
XM_017018693.2	XP_016874182.1	importin-8 isoform X3
NM_006390.3	NP_006381.2	importin-8 isoform 1
XM_017018692.1	XP_016874181.1	importin-8 isoform X2
NM_006390.4	NP_006381.2	importin-8 isoform 1
XM_017018691.1	XP_016874180.1	importin-8 isoform X1
XM_017018691.2	XP_016874180.1	importin-8 isoform X1
NM_001190995.1	NP_001177924.1	importin-8 isoform 2

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	LOC686774	XP_006237772.1
Xenopus tropicalis (tropical clawed frog)	ipo8	XP_002942294.2
	IPO8	XP_001082218.2
Bos taurus (cattle)	IPO8	NP_001193049.1
Danio rerio (zebrafish)	ipo8	NP_001037799.2
Pan troglodytes (chimpanzee)	IPO8	XP_528766.2
Mus musculus (house mouse)	Ipo8	NP_001074582.1
Homo sapiens (human)	IPO8	NP_006381.2
Canis lupus familiaris (dog)	IPO8	XP_865221.2
Gallus gallus (chicken)	IPO8	XP_416373.4

Gene Ontology
Bibliography

Related articles in PubMed

RUNX2 controls human IPO8 basal transcription in Saos-2 cells.
Xiong J, Hu Z, Wang T, Xu X, Liu J, Wu P, Che X, Li W
Molecular medicine reports14(2)1418-24(2016 Aug)

Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E.
Volpon L, Culjkovic-Kraljacic B, Osborne MJ, Ramteke A, Sun Q, Niesman A, Chook YM, Borden KL
Proceedings of the National Academy of Sciences of the United States of America113(19)5263-8(2016 May)

Functional characterization of importin ?8 as a classical nuclear localization signal receptor.
Kimoto C, Moriyama T, Tsujii A, Igarashi Y, Obuse C, Miyamoto Y, Oka M, Yoneda Y
Biochimica et biophysica acta1853(10 Pt A)2676-83(2015 Oct)

Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism.
Perera RM, Stoykova S, Nicolay BN, Ross KN, Fitamant J, Boukhali M, Lengrand J, Deshpande V, Selig MK, Ferrone CR, Settleman J, Stephanopoulos G, Dyson NJ, Zoncu R, Ramaswamy S, Haas W, Bardeesy N
Nature524(7565)361-5(2015 Aug)

KPNB1, XPO7 and IPO8 mediate the translocation ofNF-?B/p65 into the nucleus.
Liang P, Zhang H, Wang G, Li S, Cong S, Luo Y, Zhang B
Traffic (Copenhagen, Denmark)14(11)1132-43(2013 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the findings of the present study provided novel insights into the control of IPO8 transcription, and may enhance understanding regarding RUNX2 regulatory mechanisms in osteoblast differentiation, bone development, and degenerative bone disease.
Title: RUNX2 controls human IPO8 basal transcription in Saos-2 cells.

Our studies also suggest that nuclear entry is important for the prooncogenic activity of eIF4E, at least in this context. These findings position nuclear trafficking of eIF4E as a critical step in its regulation and position the importin 8-eIF4E complex as a novel therapeutic target.
Title: Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E.

importin alpha8 functions as a cNLS receptor with distinct cargo specificity, and that heterodimerization by importin alpha8 is a novel regulatory mode of cNLS binding, in addition to the autoinhibitory regulation by the importin beta binding domain.
Title: Functional characterization of importin ?8 as a classical nuclear localization signal receptor.

Knockdown of IPO8 reduced the amount of nuclear p65 following TNF stimulation. IPO8 binding to p65 is NLS independent.
Title: KPNB1, XPO7 and IPO8 mediate the translocation ofNF-?B/p65 into the nucleus.

Study provides evidence that Imp8 is required for cytoplasmic miRNA-guided gene silencing and affects nuclear localization of Ago proteins.
Title: Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs.

The following IPO8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IPO8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu32289	NM_001190995.1 Latest version!	Homo sapiens importin 8 (IPO8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu83454	XM_017018692.1 Latest version!	Homo sapiens importin 8 (IPO8), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu83455	XM_017018693.2 Latest version!	Homo sapiens importin 8 (IPO8), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu83453	XM_017018691.2 Latest version!	Homo sapiens importin 8 (IPO8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OHu05483	NM_006390.4 Latest version!	Homo sapiens importin 8 (IPO8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
View Old Accession Versions >>
OHu83455	XM_017018693.1	Homo sapiens importin 8 (IPO8), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu05483	NM_006390.3	Homo sapiens importin 8 (IPO8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
OHu83453	XM_017018691.1	Homo sapiens importin 8 (IPO8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IPO8 ( NM_001190995.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001177924.1 Homo sapiens importin 8 (IPO8), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu32289
Clone ID Related Accession (Same CDS sequence)	NM_001190995.1
Accession Version	NM_001190995.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2499bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	importin-8 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC400226.1, AK302260.1, DB067822.1, AK130090.1, EB387074.1, BG574795.1 and AA620453.1. Transcript Variant: This variant (2) lacks several 5' exons, but has an alternate 5' exon, as compared to variant 1. The resulting isoform (2) is shorter and has a different N-terminus, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK302260.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGAAAGTT TGACCCTCAA AGGGTATGCA TTGCCTCTTC AGCTAGTGAA TAACCAAACC 
ATGACAACAT GGATGGAGAT CTTCCGAACT ATTATCGACA GGACCGTTCC TCCTGAGACT 
CTGCACATTG ATGAGGATGA TAGACCAGAA CTGGTATGGT GGAAGTGTAA GAAGTGGGCA 
CTGCATATTG TAGCTCGGCT CTTTGAACGA TATGGAAGCC CAGGAAATGT CACAAAAGAA 
TACTTTGAAT TTTCTGAATT CTTTTTGAAA ACCTATGCAG TGGGCATTCA GCAGGTGCTA 
CTAAAAATTT TAGATCAATA TAGACAGAAA GAATATGTAG CTCCCCGTGT TCTTCAGCAA 
GCATTCAACT ATCTCAACCA AGGGGTGGTT CATTCTATAA CCTGGAAGCA GATGAAGCCA 
CACATACAGA ATATCTCTGA AGATGTGATT TTTTCTGTGA TGTGTTATAA AGATGAGGAT 
GAAGAGCTGT GGCAAGAAGA TCCATATGAG TATATAAGGA TGAAATTTGA TATTTTTGAA 
GATTATGCTT CTCCCACCAC AGCAGCCCAG ACTCTCTTAT ATACTGCTGC AAAGAAAAGA 
AAAGAGGTGT TGCCAAAAAT GATGGCATTC TGTTATCAAA TCCTGACAGA CCCGAACTTT 
GACCCTAGGA AGAAAGATGG AGCCCTGCAT GTGATTGGTT CCCTAGCTGA GATTTTACTG 
AAGAAGAGTT TATTCAAGGA CCAAATGGAG CTGTTTCTAC AAAATCATGT ATTTCCATTA 
TTATTGTCTA ACCTGGGATA TCTTCGAGCT AGATCTTGCT GGGTACTTCA TGCATTTAGT 
TCTTTGAAGT TCCATAATGA GCTCAATCTA AGAAATGCCG TTGAATTAGC GAAGAAGAGC 
CTGATTGAAG ATAAAGAGAT GCCTGTCAAA GTTGAAGCTG CCCTTGCTCT TCAGTCTTTA 
ATTTCTAACC AGATACAAGC TAAGGAATAT ATGAAGCCAC ATGTGAGGCC TATTATGCAG 
GAACTGTTGC ACATTGTTAG AGAGACAGAA AATGATGATG TTACTAATGT CATCCAGAAG 
ATGATATGTG AATACAGTCA AGAGGTAGCC TCAATTGCTG TTGATATGAC CCAACACTTG 
GCTGAGATAT TTGGCAAAGT TCTTCAAAGT GATGAATATG AAGAAGTTGA AGACAAAACA 
GTAATGGCTA TGGGAATTTT ACATACCATT GATACTATCT TAACAGTTGT AGAAGATCAT 
AAAGAGATTA CCCAGCAGTT AGAGAATATC TGTCTACGGA TCATTGATCT TGTTCTGCAG 
AAACATGTAA TTGAATTCTA TGAAGAAATT CTTTCCCTGG CATACAGTTT AACCTGCCAC 
AGTATTTCCC CTCAAATGTG GCAGCTTCTA GGTATACTAT ATGAAGTGTT TCAGCAGGAT 
TGCTTTGAAT ACTTTACAGA CATGATGCCT CTCCTGCATA ATTATGTGAC AATAGATACA 
GATACCTTAC TATCAAATGC AAAACATTTA GAAATTCTTT TTACAATGTG TAGGAAGGTA 
CTATGTGGAG ATGCAGGAGA AGATGCAGAG TGTCATGCAG CTAAACTTCT GGAAGTCATC 
ATTCTTCAGT GCAAAGGAAG GGGAATTGAT CAGTGCATTC CACTCTTCGT TCAACTTGTT 
TTGGAGAGAT TAACTCGAGG GGTCAAAACT AGTGAGCTTC GTACTATGTG TCTTCAGGTT 
GCAATTGCTG CCTTGTACTA CAACCCTGAT TTGCTGCTAC ATACTTTAGA ACGAATTCAG 
TTGCCTCACA ACCCTGGACC TATCACTGTA CAGTTTATAA ATCAATGGAT GAATGATACA 
GATTGTTTTC TTGGGCATCA TGACCGGAAG ATGTGTATAA TAGGACTGAG TATCCTTTTG 
GAATTGCAAA ATCGACCTCC TGCAGTAGAT GCTGTGGTGG GACAGATTGT TCCCTCAATT 
CTTTTCCTTT TCCTTGGCCT AAAGCAGGTC TGTGCTACTA GACAACTGGT AAACCGGGAA 
GATCGTTCAA AAGCAGAGAA AGCTGATATG GAAGAAAATG AGGAGATTTC AAGTGATGAA 
GAGGAGACAA ATGTAACTGC TCAAGCAATG CAGTCAAATA ATGGAAGAGG TGAAGATGAG 
GAGGAGGAAG ATGATGACTG GGATGAAGAA GTATTGGAAG AAACCGCGCT TGAGGGGTTC 
AGTACTCCAC TTGACCTTGA CAATAGTGTG GATGAATATC AGTTTTTTAC ACAAGCTCTG 
ATAACTGTGC AGAGTCGAGA TGCAGCCTGG TACCAGCTGC TGATGGCACC ACTCAGCGAG 
GATCAGAGGA CAGCACTGCA GGAGGTGTAC ACACTGGCAG AGCACCGACG GACGGTGGCA 
GAGGCAAAGA AGAAGATTGA ACAACAGGGA GGCTTCACCT TTGAAAACAA AGGAGTCCTC 
TCCGCATTTA ATTTTGGGAC TGTGCCCAGC AACAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001177924.1
CDS	326..2824
Translation	MESLTLKGYALPLQLVNNQTMTTWMEIFRTIIDRTVPPETLHIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVGIQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVIFSVMCYKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQILTDPNFDPRKKDGALHVIGSLAEILLKKSLFKDQMELFLQNHVFPLLLSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPVKVEAALALQSLISNQIQAKEYMKPHVRPIMQELLHIVRETENDDVTNVIQKMICEYSQEVASIAVDMTQHLAEIFGKVLQSDEYEEVEDKTVMAMGILHTIDTILTVVEDHKEITQQLENICLRIIDLVLQKHVIEFYEEILSLAYSLTCHSISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTIDTDTLLSNAKHLEILFTMCRKVLCGDAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLTRGVKTSELRTMCLQVAIAALYYNPDLLLHTLERIQLPHNPGPITVQFINQWMNDTDCFLGHHDRKMCIIGLSILLELQNRPPAVDAVVGQIVPSILFLFLGLKQVCATRQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETALEGFSTPLDLDNSVDEYQFFTQALITVQSRDAAWYQLLMAPLSEDQRTALQEVYTLAEHRRTVAEAKKKIEQQGGFTFENKGVLSAFNFGTVPSNN

Target ORF information:

RefSeq Version	NM_001190995.1
Organism	Homo sapiens(human)
Definition	Homo sapiens importin 8 (IPO8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001190995.1

ORF Insert Sequence:

ATGGAAAGTT TGACCCTCAA AGGGTATGCA TTGCCTCTTC AGCTAGTGAA TAACCAAACC 
ATGACAACAT GGATGGAGAT CTTCCGAACT ATTATCGACA GGACCGTTCC TCCTGAGACT 
CTGCACATTG ATGAGGATGA TAGACCAGAA CTGGTATGGT GGAAGTGTAA GAAGTGGGCA 
CTGCATATTG TAGCTCGGCT CTTTGAACGA TATGGAAGCC CAGGAAATGT CACAAAAGAA 
TACTTTGAAT TTTCTGAATT CTTTTTGAAA ACCTATGCAG TGGGCATTCA GCAGGTGCTA 
CTAAAAATTT TAGATCAATA TAGACAGAAA GAATATGTAG CTCCCCGTGT TCTTCAGCAA 
GCATTCAACT ATCTCAACCA AGGGGTGGTT CATTCTATAA CCTGGAAGCA GATGAAGCCA 
CACATACAGA ATATCTCTGA AGATGTGATT TTTTCTGTGA TGTGTTATAA AGATGAGGAT 
GAAGAGCTGT GGCAAGAAGA TCCATATGAG TATATAAGGA TGAAATTTGA TATTTTTGAA 
GATTATGCTT CTCCCACCAC AGCAGCCCAG ACTCTCTTAT ATACTGCTGC AAAGAAAAGA 
AAAGAGGTGT TGCCAAAAAT GATGGCATTC TGTTATCAAA TCCTGACAGA CCCGAACTTT 
GACCCTAGGA AGAAAGATGG AGCCCTGCAT GTGATTGGTT CCCTAGCTGA GATTTTACTG 
AAGAAGAGTT TATTCAAGGA CCAAATGGAG CTGTTTCTAC AAAATCATGT ATTTCCATTA 
TTATTGTCTA ACCTGGGATA TCTTCGAGCT AGATCTTGCT GGGTACTTCA TGCATTTAGT 
TCTTTGAAGT TCCATAATGA GCTCAATCTA AGAAATGCCG TTGAATTAGC GAAGAAGAGC 
CTGATTGAAG ATAAAGAGAT GCCTGTCAAA GTTGAAGCTG CCCTTGCTCT TCAGTCTTTA 
ATTTCTAACC AGATACAAGC TAAGGAATAT ATGAAGCCAC ATGTGAGGCC TATTATGCAG 
GAACTGTTGC ACATTGTTAG AGAGACAGAA AATGATGATG TTACTAATGT CATCCAGAAG 
ATGATATGTG AATACAGTCA AGAGGTAGCC TCAATTGCTG TTGATATGAC CCAACACTTG 
GCTGAGATAT TTGGCAAAGT TCTTCAAAGT GATGAATATG AAGAAGTTGA AGACAAAACA 
GTAATGGCTA TGGGAATTTT ACATACCATT GATACTATCT TAACAGTTGT AGAAGATCAT 
AAAGAGATTA CCCAGCAGTT AGAGAATATC TGTCTACGGA TCATTGATCT TGTTCTGCAG 
AAACATGTAA TTGAATTCTA TGAAGAAATT CTTTCCCTGG CATACAGTTT AACCTGCCAC 
AGTATTTCCC CTCAAATGTG GCAGCTTCTA GGTATACTAT ATGAAGTGTT TCAGCAGGAT 
TGCTTTGAAT ACTTTACAGA CATGATGCCT CTCCTGCATA ATTATGTGAC AATAGATACA 
GATACCTTAC TATCAAATGC AAAACATTTA GAAATTCTTT TTACAATGTG TAGGAAGGTA 
CTATGTGGAG ATGCAGGAGA AGATGCAGAG TGTCATGCAG CTAAACTTCT GGAAGTCATC 
ATTCTTCAGT GCAAAGGAAG GGGAATTGAT CAGTGCATTC CACTCTTCGT TCAACTTGTT 
TTGGAGAGAT TAACTCGAGG GGTCAAAACT AGTGAGCTTC GTACTATGTG TCTTCAGGTT 
GCAATTGCTG CCTTGTACTA CAACCCTGAT TTGCTGCTAC ATACTTTAGA ACGAATTCAG 
TTGCCTCACA ACCCTGGACC TATCACTGTA CAGTTTATAA ATCAATGGAT GAATGATACA 
GATTGTTTTC TTGGGCATCA TGACCGGAAG ATGTGTATAA TAGGACTGAG TATCCTTTTG 
GAATTGCAAA ATCGACCTCC TGCAGTAGAT GCTGTGGTGG GACAGATTGT TCCCTCAATT 
CTTTTCCTTT TCCTTGGCCT AAAGCAGGTC TGTGCTACTA GACAACTGGT AAACCGGGAA 
GATCGTTCAA AAGCAGAGAA AGCTGATATG GAAGAAAATG AGGAGATTTC AAGTGATGAA 
GAGGAGACAA ATGTAACTGC TCAAGCAATG CAGTCAAATA ATGGAAGAGG TGAAGATGAG 
GAGGAGGAAG ATGATGACTG GGATGAAGAA GTATTGGAAG AAACCGCGCT TGAGGGGTTC 
AGTACTCCAC TTGACCTTGA CAATAGTGTG GATGAATATC AGTTTTTTAC ACAAGCTCTG 
ATAACTGTGC AGAGTCGAGA TGCAGCCTGG TACCAGCTGC TGATGGCACC ACTCAGCGAG 
GATCAGAGGA CAGCACTGCA GGAGGTGTAC ACACTGGCAG AGCACCGACG GACGGTGGCA 
GAGGCAAAGA AGAAGATTGA ACAACAGGGA GGCTTCACCT TTGAAAACAA AGGAGTCCTC 
TCCGCATTTA ATTTTGGGAC TGTGCCCAGC AACAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IPO8 ( XM_017018692.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016874181.1 Homo sapiens importin 8 (IPO8), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu83454
Clone ID Related Accession (Same CDS sequence)	XM_017018692.1
Accession Version	XM_017018692.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2928bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	importin-8 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGACAC AATACTGGCC AGATCGAGAA CCTCCACCAG GAGAAGCAAT ATTTCCATTC 
AACATTCACG AAAACGATCG CCAGCAAATA CGTGATAACA TTGTGGAAGG AATAATTCGG 
TCTCCAGATT TAGTGAGAGT CCAATTAACA ATGTGTCTCC GTGCCATCAT AAAACATGAT 
TTTCCTGGTC ACTGGCCAGG AGTGGTCGAC AAGATAGACT ATTACTTGCA ATCACAGAGC 
AGTGCAAGCT GGCTTGGCAG TTTATTATGC CTGTATCAAC TGGTGAAGAC ATATGAATAT 
AAGAAAGCAG AAGAGAGAGA ACCTCTTATA ATAGCAATGC AGATATTCCT GCCTCGTATT 
CAGCAACAAA TTGTTCAGCT CCTTCCTGAT TCCTCCTATT ATTCTGTATT ACTGCAGAAA 
CAAATTCTGA AAATCTTTTA TGCACTTGTT CAGTATGCAT TGCCTCTTCA GCTAGTGAAT 
AACCAAACCA TGACAACATG GATGGAGATC TTCCGAACTA TTATCGACAG GACCGTTCCT 
CCTGAGACTC TGCACATTGA TGAGGATGAT AGACCAGAAC TGGTATGGTG GAAGTGTAAG 
AAGTGGGCAC TGCATATTGT AGCTCGGCTC TTTGAACGAT ATGGAAGCCC AGGAAATGTC 
ACAAAAGAAT ACTTTGAATT TTCTGAATTC TTTTTGAAAA CCTATGCAGT GGGCATTCAG 
CAGGTGCTAC TAAAAATTTT AGATCAATAT AGACAGAAAG AATATGTAGC TCCCCGTGTT 
CTTCAGCAAG CATTCAACTA TCTCAACCAA GGGGTGGTTC ATTCTATAAC CTGGAAGCAG 
ATGAAGCCAC ACATACAGAA TATCTCTGAA GATGTGATTT TTTCTGTGAT GTGTTATAAA 
GATGAGGATG AAGAGCTGTG GCAAGAAGAT CCATATGAGT ATATAAGGAT GAAATTTGAT 
ATTTTTGAAG ATTATGCTTC TCCCACCACA GCAGCCCAGA CTCTCTTATA TACTGCTGCA 
AAGAAAAGAA AAGAGGTGTT GCCAAAAATG ATGGCATTCT GTTATCAAAT CCTGACAGAC 
CCGAACTTTG ACCCTAGGAA GAAAGATGGA GCCCTGCATG TGATTGGTTC CCTAGCTGAG 
ATTTTACTGA AGAAGAGTTT ATTCAAGGAC CAAATGGAGC TGTTTCTACA AAATCATGTA 
TTTCCATTAT TATTGTCTAA CCTGGGATAT CTTCGAGCTA GATCTTGCTG GGTACTTCAT 
GCATTTAGTT CTTTGAAGTT CCATAATGAG CTCAATCTAA GAAATGCCGT TGAATTAGCG 
AAGAAGAGCC TGATTGAAGA TAAAGAGATG CCTGTCAAAG TTGAAGCTGC CCTTGCTCTT 
CAGTCTTTAA TTTCTAACCA GATACAAGCT AAGGAATATA TGAAGCCACA TGTGAGGCCT 
ATTATGCAGG AACTGTTGCA CATTGTTAGA GAGACAGAAA ATGATGATGT TACTAATGTC 
ATCCAGAAGA TGATATGTGA ATACAGTCAA GAGGTAGCCT CAATTGCTGT TGATATGACC 
CAACACTTGG CTGAGATATT TGGCAAAGTT CTTCAAAGTG ATGAATATGA AGAAGTTGAA 
GACAAAACAG TAATGGCTAT GGGAATTTTA CATACCATTG ATACTATCTT AACAGTTGTA 
GAAGATCATA AAGAGATTAC CCAGCAGTTA GAGAATATCT GTCTACGGAT CATTGATCTT 
GTTCTGCAGA AACATGTAAT TGAATTCTAT GAAGAAATTC TTTCCCTGGC ATACAGTTTA 
ACCTGCCACA GTATTTCCCC TCAAATGTGG CAGCTTCTAG GTATACTATA TGAAGTGTTT 
CAGCAGGATT GCTTTGAATA CTTTACAGAC ATGATGCCTC TCCTGCATAA TTATGTGACA 
ATAGATACAG ATACCTTACT ATCAAATGCA AAACATTTAG AAATTCTTTT TACAATGTGT 
AGGAAGGTAC TATGTGGAGA TGCAGGAGAA GATGCAGAGT GTCATGCAGC TAAACTTCTG 
GAAGTCATCA TTCTTCAGTG CAAAGGAAGG GGAATTGATC AGTGCATTCC ACTCTTCGTT 
CAACTTGTTT TGGAGAGATT AACTCGAGGG GTCAAAACTA GTGAGCTTCG TACTATGTGT 
CTTCAGGTTG CAATTGCTGC CTTGTACTAC AACCCTGATT TGCTGCTACA TACTTTAGAA 
CGAATTCAGT TGCCTCACAA CCCTGGACCT ATCACTGTAC AGTTTATAAA TCAATGGATG 
AATGATACAG ATTGTTTTCT TGGGCATCAT GACCGGAAGA TGTGTATAAT AGGACTGAGT 
ATCCTTTTGG AATTGCAAAA TCGACCTCCT GCAGTAGATG CTGTGGTGGG ACAGATTGTT 
CCCTCAATTC TTTTCCTTTT CCTTGGCCTA AAGCAGGTCT GTGCTACTAG ACAACTGGTA 
AACCGGGAAG ATCGTTCAAA AGCAGAGAAA GCTGATATGG AAGAAAATGA GGAGATTTCA 
AGTGATGAAG AGGAGACAAA TGTAACTGCT CAAGCAATGC AGTCAAATAA TGGAAGAGGT 
GAAGATGAGG AGGAGGAAGA TGATGACTGG GATGAAGAAG TATTGGAAGA AACCGCGCTT 
GAGGGGTTCA GTACTCCACT TGACCTTGAC AATAGTGTGG ATGAATATCA GTTTTTTACA 
CAAGCTCTGA TAACTGTGCA GAGTCGAGAT GCAGCCTGGT ACCAGCTGCT GATGGCACCA 
CTCAGCGAGG ATCAGAGGAC AGCACTGCAG GAGGTGTACA CACTGGCAGA GCACCGACGG 
ACGGTGGCAG AGGCAAAGAA GAAGATTGAA CAACAGGGAG GCTTCACCTT TGAAAACAAA 
GGAGTCCTCT CCGCATTTAA TTTTGGGACT GTGCCCAGCA ACAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016874181.1
CDS	92..3019
Translation	MVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRAIIKHDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLPRIQQQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRTVPPETLHIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVGIQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVIFSVMCYKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQILTDPNFDPRKKDGALHVIGSLAEILLKKSLFKDQMELFLQNHVFPLLLSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPVKVEAALALQSLISNQIQAKEYMKPHVRPIMQELLHIVRETENDDVTNVIQKMICEYSQEVASIAVDMTQHLAEIFGKVLQSDEYEEVEDKTVMAMGILHTIDTILTVVEDHKEITQQLENICLRIIDLVLQKHVIEFYEEILSLAYSLTCHSISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTIDTDTLLSNAKHLEILFTMCRKVLCGDAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLTRGVKTSELRTMCLQVAIAALYYNPDLLLHTLERIQLPHNPGPITVQFINQWMNDTDCFLGHHDRKMCIIGLSILLELQNRPPAVDAVVGQIVPSILFLFLGLKQVCATRQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETALEGFSTPLDLDNSVDEYQFFTQALITVQSRDAAWYQLLMAPLSEDQRTALQEVYTLAEHRRTVAEAKKKIEQQGGFTFENKGVLSAFNFGTVPSNN

Target ORF information:

RefSeq Version	XM_017018692.1
Organism	Homo sapiens(human)
Definition	Homo sapiens importin 8 (IPO8), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017018692.1

ORF Insert Sequence:

ATGGTGACAC AATACTGGCC AGATCGAGAA CCTCCACCAG GAGAAGCAAT ATTTCCATTC 
AACATTCACG AAAACGATCG CCAGCAAATA CGTGATAACA TTGTGGAAGG AATAATTCGG 
TCTCCAGATT TAGTGAGAGT CCAATTAACA ATGTGTCTCC GTGCCATCAT AAAACATGAT 
TTTCCTGGTC ACTGGCCAGG AGTGGTCGAC AAGATAGACT ATTACTTGCA ATCACAGAGC 
AGTGCAAGCT GGCTTGGCAG TTTATTATGC CTGTATCAAC TGGTGAAGAC ATATGAATAT 
AAGAAAGCAG AAGAGAGAGA ACCTCTTATA ATAGCAATGC AGATATTCCT GCCTCGTATT 
CAGCAACAAA TTGTTCAGCT CCTTCCTGAT TCCTCCTATT ATTCTGTATT ACTGCAGAAA 
CAAATTCTGA AAATCTTTTA TGCACTTGTT CAGTATGCAT TGCCTCTTCA GCTAGTGAAT 
AACCAAACCA TGACAACATG GATGGAGATC TTCCGAACTA TTATCGACAG GACCGTTCCT 
CCTGAGACTC TGCACATTGA TGAGGATGAT AGACCAGAAC TGGTATGGTG GAAGTGTAAG 
AAGTGGGCAC TGCATATTGT AGCTCGGCTC TTTGAACGAT ATGGAAGCCC AGGAAATGTC 
ACAAAAGAAT ACTTTGAATT TTCTGAATTC TTTTTGAAAA CCTATGCAGT GGGCATTCAG 
CAGGTGCTAC TAAAAATTTT AGATCAATAT AGACAGAAAG AATATGTAGC TCCCCGTGTT 
CTTCAGCAAG CATTCAACTA TCTCAACCAA GGGGTGGTTC ATTCTATAAC CTGGAAGCAG 
ATGAAGCCAC ACATACAGAA TATCTCTGAA GATGTGATTT TTTCTGTGAT GTGTTATAAA 
GATGAGGATG AAGAGCTGTG GCAAGAAGAT CCATATGAGT ATATAAGGAT GAAATTTGAT 
ATTTTTGAAG ATTATGCTTC TCCCACCACA GCAGCCCAGA CTCTCTTATA TACTGCTGCA 
AAGAAAAGAA AAGAGGTGTT GCCAAAAATG ATGGCATTCT GTTATCAAAT CCTGACAGAC 
CCGAACTTTG ACCCTAGGAA GAAAGATGGA GCCCTGCATG TGATTGGTTC CCTAGCTGAG 
ATTTTACTGA AGAAGAGTTT ATTCAAGGAC CAAATGGAGC TGTTTCTACA AAATCATGTA 
TTTCCATTAT TATTGTCTAA CCTGGGATAT CTTCGAGCTA GATCTTGCTG GGTACTTCAT 
GCATTTAGTT CTTTGAAGTT CCATAATGAG CTCAATCTAA GAAATGCCGT TGAATTAGCG 
AAGAAGAGCC TGATTGAAGA TAAAGAGATG CCTGTCAAAG TTGAAGCTGC CCTTGCTCTT 
CAGTCTTTAA TTTCTAACCA GATACAAGCT AAGGAATATA TGAAGCCACA TGTGAGGCCT 
ATTATGCAGG AACTGTTGCA CATTGTTAGA GAGACAGAAA ATGATGATGT TACTAATGTC 
ATCCAGAAGA TGATATGTGA ATACAGTCAA GAGGTAGCCT CAATTGCTGT TGATATGACC 
CAACACTTGG CTGAGATATT TGGCAAAGTT CTTCAAAGTG ATGAATATGA AGAAGTTGAA 
GACAAAACAG TAATGGCTAT GGGAATTTTA CATACCATTG ATACTATCTT AACAGTTGTA 
GAAGATCATA AAGAGATTAC CCAGCAGTTA GAGAATATCT GTCTACGGAT CATTGATCTT 
GTTCTGCAGA AACATGTAAT TGAATTCTAT GAAGAAATTC TTTCCCTGGC ATACAGTTTA 
ACCTGCCACA GTATTTCCCC TCAAATGTGG CAGCTTCTAG GTATACTATA TGAAGTGTTT 
CAGCAGGATT GCTTTGAATA CTTTACAGAC ATGATGCCTC TCCTGCATAA TTATGTGACA 
ATAGATACAG ATACCTTACT ATCAAATGCA AAACATTTAG AAATTCTTTT TACAATGTGT 
AGGAAGGTAC TATGTGGAGA TGCAGGAGAA GATGCAGAGT GTCATGCAGC TAAACTTCTG 
GAAGTCATCA TTCTTCAGTG CAAAGGAAGG GGAATTGATC AGTGCATTCC ACTCTTCGTT 
CAACTTGTTT TGGAGAGATT AACTCGAGGG GTCAAAACTA GTGAGCTTCG TACTATGTGT 
CTTCAGGTTG CAATTGCTGC CTTGTACTAC AACCCTGATT TGCTGCTACA TACTTTAGAA 
CGAATTCAGT TGCCTCACAA CCCTGGACCT ATCACTGTAC AGTTTATAAA TCAATGGATG 
AATGATACAG ATTGTTTTCT TGGGCATCAT GACCGGAAGA TGTGTATAAT AGGACTGAGT 
ATCCTTTTGG AATTGCAAAA TCGACCTCCT GCAGTAGATG CTGTGGTGGG ACAGATTGTT 
CCCTCAATTC TTTTCCTTTT CCTTGGCCTA AAGCAGGTCT GTGCTACTAG ACAACTGGTA 
AACCGGGAAG ATCGTTCAAA AGCAGAGAAA GCTGATATGG AAGAAAATGA GGAGATTTCA 
AGTGATGAAG AGGAGACAAA TGTAACTGCT CAAGCAATGC AGTCAAATAA TGGAAGAGGT 
GAAGATGAGG AGGAGGAAGA TGATGACTGG GATGAAGAAG TATTGGAAGA AACCGCGCTT 
GAGGGGTTCA GTACTCCACT TGACCTTGAC AATAGTGTGG ATGAATATCA GTTTTTTACA 
CAAGCTCTGA TAACTGTGCA GAGTCGAGAT GCAGCCTGGT ACCAGCTGCT GATGGCACCA 
CTCAGCGAGG ATCAGAGGAC AGCACTGCAG GAGGTGTACA CACTGGCAGA GCACCGACGG 
ACGGTGGCAG AGGCAAAGAA GAAGATTGAA CAACAGGGAG GCTTCACCTT TGAAAACAAA 
GGAGTCCTCT CCGCATTTAA TTTTGGGACT GTGCCCAGCA ACAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IPO8 ( XM_017018693.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016874182.1 Homo sapiens importin 8 (IPO8), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu83455
Clone ID Related Accession (Same CDS sequence)	XM_017018693.1 , XM_017018693.2
Accession Version	XM_017018693.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1599bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	importin-8 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCTCA ACCGGATCAT CCAGGCGCTG AAGGGCACCA TCGACCCGAA GTTGCGGATT 
GCAGCCGAGA ACGAGCTCAA CCAGTCCTAC AAGATTATCA ATTTTGCCCC CAGTTTACTT 
CGGATTATAG TCTCTGACCA TGTGGAATTC CCAGTACGAC AGGCAGCTGC CATTTACCTG 
AAGAACATGG TGACACAATA CTGGCCAGAT CGAGAACCTC CACCAGGAGA AGCAATATTT 
CCATTCAACA TTCACGAAAA CGATCGCCAG CAAATACGTG ATAACATTGT GGAAGGAATA 
ATTCGGTCTC CAGATTTAGT GAGAGTCCAA TTAACAATGT GTCTCCGTGC CATCATAAAA 
CATGATTTTC CTGGTCACTG GCCAGGAGTG GTCGACAAGA TAGACTATTA CTTGCAATCA 
CAGAGCAGTG CAAGCTGGCT TGGCAGTTTA TTATGCCTGT ATCAACTGGT GAAGACATAT 
GAATATAAGA AAGCAGAAGA GAGAGAACCT CTTATAATAG CAATGCAGAT ATTCCTGCCT 
CGTATTCAGC AACAAATTGT TCAGCTCCTT CCTGATTCCT CCTATTATTC TGTATTACTG 
CAGAAACAAA TTCTGAAAAT CTTTTATGCA CTTGTTCAGT ATGCATTGCC TCTTCAGCTA 
GTGAATAACC AAACCATGAC AACATGGATG GAGATCTTCC GAACTATTAT CGACAGGACC 
GTTCCTCCTG AGACTCTGCA CATTGATGAG GATGATAGAC CAGAACTGGT ATGGTGGAAG 
TGTAAGAAGT GGGCACTGCA TATTGTAGCT CGGCTCTTTG AACGATATGG AAGCCCAGGA 
AATGTCACAA AAGAATACTT TGAATTTTCT GAATTCTTTT TGAAAACCTA TGCAGTGGGC 
ATTCAGCAGG TGCTACTAAA AATTTTAGAT CAATATAGAC AGAAAGAATA TGTAGCTCCC 
CGTGTTCTTC AGCAAGCATT CAACTATCTC AACCAAGGGG TGGTTCATTC TATAACCTGG 
AAGCAGATGA AGCCACACAT ACAGAATATC TCTGAAGATG TGATTTTTTC TGTGATGTGT 
TATAAAGATG AGGATGAAGA GCTGTGGCAA GAAGATCCAT ATGAGTATAT AAGGATGAAA 
TTTGATATTT TTGAAGATTA TGCTTCTCCC ACCACAGCAG CCCAGACTCT CTTATATACT 
GCTGCAAAGA AAAGAAAAGA GGTGTTGCCA AAAATGATGG CATTCTGTTA TCAAATCCTG 
ACAGACCCGA ACTTTGACCC TAGGAAGAAA GATGGAGCCC TGCATGTGAT TGGTTCCCTA 
GCTGAGATTT TACTGAAGAA GAGTTTATTC AAGGACCAAA TGGAGCTGTT TCTACAAAAT 
CATGTATTTC CATTATTATT GTCTAACCTG GGATATCTTC GAGCTAGATC TTGCTGGGTA 
CTTCATGCAT TTAGTTCTTT GAAGTTCCAT AATGAGCTCA ATCTAAGAAA TGCCGTTGAA 
TTAGCGAAGA AGAGCCTGAT TGAAGATAAA GAGATGCCTG TCAAAGTTGA AGCTGCCCTT 
GCTCTTCAGT CTTTAATTTC TAACCAGATA CAAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016874182.1
CDS	342..1940
Translation	MDLNRIIQALKGTIDPKLRIAAENELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRAIIKHDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLPRIQQQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRTVPPETLHIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVGIQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVIFSVMCYKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQILTDPNFDPRKKDGALHVIGSLAEILLKKSLFKDQMELFLQNHVFPLLLSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPVKVEAALALQSLISNQIQG

Target ORF information:

RefSeq Version	XM_017018693.1
Organism	Homo sapiens(human)
Definition	Homo sapiens importin 8 (IPO8), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017018693.1

ORF Insert Sequence:

ATGGACCTCA ACCGGATCAT CCAGGCGCTG AAGGGCACCA TCGACCCGAA GTTGCGGATT 
GCAGCCGAGA ACGAGCTCAA CCAGTCCTAC AAGATTATCA ATTTTGCCCC CAGTTTACTT 
CGGATTATAG TCTCTGACCA TGTGGAATTC CCAGTACGAC AGGCAGCTGC CATTTACCTG 
AAGAACATGG TGACACAATA CTGGCCAGAT CGAGAACCTC CACCAGGAGA AGCAATATTT 
CCATTCAACA TTCACGAAAA CGATCGCCAG CAAATACGTG ATAACATTGT GGAAGGAATA 
ATTCGGTCTC CAGATTTAGT GAGAGTCCAA TTAACAATGT GTCTCCGTGC CATCATAAAA 
CATGATTTTC CTGGTCACTG GCCAGGAGTG GTCGACAAGA TAGACTATTA CTTGCAATCA 
CAGAGCAGTG CAAGCTGGCT TGGCAGTTTA TTATGCCTGT ATCAACTGGT GAAGACATAT 
GAATATAAGA AAGCAGAAGA GAGAGAACCT CTTATAATAG CAATGCAGAT ATTCCTGCCT 
CGTATTCAGC AACAAATTGT TCAGCTCCTT CCTGATTCCT CCTATTATTC TGTATTACTG 
CAGAAACAAA TTCTGAAAAT CTTTTATGCA CTTGTTCAGT ATGCATTGCC TCTTCAGCTA 
GTGAATAACC AAACCATGAC AACATGGATG GAGATCTTCC GAACTATTAT CGACAGGACC 
GTTCCTCCTG AGACTCTGCA CATTGATGAG GATGATAGAC CAGAACTGGT ATGGTGGAAG 
TGTAAGAAGT GGGCACTGCA TATTGTAGCT CGGCTCTTTG AACGATATGG AAGCCCAGGA 
AATGTCACAA AAGAATACTT TGAATTTTCT GAATTCTTTT TGAAAACCTA TGCAGTGGGC 
ATTCAGCAGG TGCTACTAAA AATTTTAGAT CAATATAGAC AGAAAGAATA TGTAGCTCCC 
CGTGTTCTTC AGCAAGCATT CAACTATCTC AACCAAGGGG TGGTTCATTC TATAACCTGG 
AAGCAGATGA AGCCACACAT ACAGAATATC TCTGAAGATG TGATTTTTTC TGTGATGTGT 
TATAAAGATG AGGATGAAGA GCTGTGGCAA GAAGATCCAT ATGAGTATAT AAGGATGAAA 
TTTGATATTT TTGAAGATTA TGCTTCTCCC ACCACAGCAG CCCAGACTCT CTTATATACT 
GCTGCAAAGA AAAGAAAAGA GGTGTTGCCA AAAATGATGG CATTCTGTTA TCAAATCCTG 
ACAGACCCGA ACTTTGACCC TAGGAAGAAA GATGGAGCCC TGCATGTGAT TGGTTCCCTA 
GCTGAGATTT TACTGAAGAA GAGTTTATTC AAGGACCAAA TGGAGCTGTT TCTACAAAAT 
CATGTATTTC CATTATTATT GTCTAACCTG GGATATCTTC GAGCTAGATC TTGCTGGGTA 
CTTCATGCAT TTAGTTCTTT GAAGTTCCAT AATGAGCTCA ATCTAAGAAA TGCCGTTGAA 
TTAGCGAAGA AGAGCCTGAT TGAAGATAAA GAGATGCCTG TCAAAGTTGA AGCTGCCCTT 
GCTCTTCAGT CTTTAATTTC TAACCAGATA CAAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IPO8 ( XM_017018693.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016874182.1 Homo sapiens importin 8 (IPO8), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu83455
Clone ID Related Accession (Same CDS sequence)	XM_017018693.1 , XM_017018693.2
Accession Version	XM_017018693.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1599bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	importin-8 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017018693.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCTCA ACCGGATCAT CCAGGCGCTG AAGGGCACCA TCGACCCGAA GTTGCGGATT 
GCAGCCGAGA ACGAGCTCAA CCAGTCCTAC AAGATTATCA ATTTTGCCCC CAGTTTACTT 
CGGATTATAG TCTCTGACCA TGTGGAATTC CCAGTACGAC AGGCAGCTGC CATTTACCTG 
AAGAACATGG TGACACAATA CTGGCCAGAT CGAGAACCTC CACCAGGAGA AGCAATATTT 
CCATTCAACA TTCACGAAAA CGATCGCCAG CAAATACGTG ATAACATTGT GGAAGGAATA 
ATTCGGTCTC CAGATTTAGT GAGAGTCCAA TTAACAATGT GTCTCCGTGC CATCATAAAA 
CATGATTTTC CTGGTCACTG GCCAGGAGTG GTCGACAAGA TAGACTATTA CTTGCAATCA 
CAGAGCAGTG CAAGCTGGCT TGGCAGTTTA TTATGCCTGT ATCAACTGGT GAAGACATAT 
GAATATAAGA AAGCAGAAGA GAGAGAACCT CTTATAATAG CAATGCAGAT ATTCCTGCCT 
CGTATTCAGC AACAAATTGT TCAGCTCCTT CCTGATTCCT CCTATTATTC TGTATTACTG 
CAGAAACAAA TTCTGAAAAT CTTTTATGCA CTTGTTCAGT ATGCATTGCC TCTTCAGCTA 
GTGAATAACC AAACCATGAC AACATGGATG GAGATCTTCC GAACTATTAT CGACAGGACC 
GTTCCTCCTG AGACTCTGCA CATTGATGAG GATGATAGAC CAGAACTGGT ATGGTGGAAG 
TGTAAGAAGT GGGCACTGCA TATTGTAGCT CGGCTCTTTG AACGATATGG AAGCCCAGGA 
AATGTCACAA AAGAATACTT TGAATTTTCT GAATTCTTTT TGAAAACCTA TGCAGTGGGC 
ATTCAGCAGG TGCTACTAAA AATTTTAGAT CAATATAGAC AGAAAGAATA TGTAGCTCCC 
CGTGTTCTTC AGCAAGCATT CAACTATCTC AACCAAGGGG TGGTTCATTC TATAACCTGG 
AAGCAGATGA AGCCACACAT ACAGAATATC TCTGAAGATG TGATTTTTTC TGTGATGTGT 
TATAAAGATG AGGATGAAGA GCTGTGGCAA GAAGATCCAT ATGAGTATAT AAGGATGAAA 
TTTGATATTT TTGAAGATTA TGCTTCTCCC ACCACAGCAG CCCAGACTCT CTTATATACT 
GCTGCAAAGA AAAGAAAAGA GGTGTTGCCA AAAATGATGG CATTCTGTTA TCAAATCCTG 
ACAGACCCGA ACTTTGACCC TAGGAAGAAA GATGGAGCCC TGCATGTGAT TGGTTCCCTA 
GCTGAGATTT TACTGAAGAA GAGTTTATTC AAGGACCAAA TGGAGCTGTT TCTACAAAAT 
CATGTATTTC CATTATTATT GTCTAACCTG GGATATCTTC GAGCTAGATC TTGCTGGGTA 
CTTCATGCAT TTAGTTCTTT GAAGTTCCAT AATGAGCTCA ATCTAAGAAA TGCCGTTGAA 
TTAGCGAAGA AGAGCCTGAT TGAAGATAAA GAGATGCCTG TCAAAGTTGA AGCTGCCCTT 
GCTCTTCAGT CTTTAATTTC TAACCAGATA CAAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016874182.1
CDS	340..1938
Translation	MDLNRIIQALKGTIDPKLRIAAENELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRAIIKHDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLPRIQQQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRTVPPETLHIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVGIQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVIFSVMCYKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQILTDPNFDPRKKDGALHVIGSLAEILLKKSLFKDQMELFLQNHVFPLLLSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPVKVEAALALQSLISNQIQG

Target ORF information:

RefSeq Version	XM_017018693.2
Organism	Homo sapiens(human)
Definition	Homo sapiens importin 8 (IPO8), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017018693.2

ORF Insert Sequence:

ATGGACCTCA ACCGGATCAT CCAGGCGCTG AAGGGCACCA TCGACCCGAA GTTGCGGATT 
GCAGCCGAGA ACGAGCTCAA CCAGTCCTAC AAGATTATCA ATTTTGCCCC CAGTTTACTT 
CGGATTATAG TCTCTGACCA TGTGGAATTC CCAGTACGAC AGGCAGCTGC CATTTACCTG 
AAGAACATGG TGACACAATA CTGGCCAGAT CGAGAACCTC CACCAGGAGA AGCAATATTT 
CCATTCAACA TTCACGAAAA CGATCGCCAG CAAATACGTG ATAACATTGT GGAAGGAATA 
ATTCGGTCTC CAGATTTAGT GAGAGTCCAA TTAACAATGT GTCTCCGTGC CATCATAAAA 
CATGATTTTC CTGGTCACTG GCCAGGAGTG GTCGACAAGA TAGACTATTA CTTGCAATCA 
CAGAGCAGTG CAAGCTGGCT TGGCAGTTTA TTATGCCTGT ATCAACTGGT GAAGACATAT 
GAATATAAGA AAGCAGAAGA GAGAGAACCT CTTATAATAG CAATGCAGAT ATTCCTGCCT 
CGTATTCAGC AACAAATTGT TCAGCTCCTT CCTGATTCCT CCTATTATTC TGTATTACTG 
CAGAAACAAA TTCTGAAAAT CTTTTATGCA CTTGTTCAGT ATGCATTGCC TCTTCAGCTA 
GTGAATAACC AAACCATGAC AACATGGATG GAGATCTTCC GAACTATTAT CGACAGGACC 
GTTCCTCCTG AGACTCTGCA CATTGATGAG GATGATAGAC CAGAACTGGT ATGGTGGAAG 
TGTAAGAAGT GGGCACTGCA TATTGTAGCT CGGCTCTTTG AACGATATGG AAGCCCAGGA 
AATGTCACAA AAGAATACTT TGAATTTTCT GAATTCTTTT TGAAAACCTA TGCAGTGGGC 
ATTCAGCAGG TGCTACTAAA AATTTTAGAT CAATATAGAC AGAAAGAATA TGTAGCTCCC 
CGTGTTCTTC AGCAAGCATT CAACTATCTC AACCAAGGGG TGGTTCATTC TATAACCTGG 
AAGCAGATGA AGCCACACAT ACAGAATATC TCTGAAGATG TGATTTTTTC TGTGATGTGT 
TATAAAGATG AGGATGAAGA GCTGTGGCAA GAAGATCCAT ATGAGTATAT AAGGATGAAA 
TTTGATATTT TTGAAGATTA TGCTTCTCCC ACCACAGCAG CCCAGACTCT CTTATATACT 
GCTGCAAAGA AAAGAAAAGA GGTGTTGCCA AAAATGATGG CATTCTGTTA TCAAATCCTG 
ACAGACCCGA ACTTTGACCC TAGGAAGAAA GATGGAGCCC TGCATGTGAT TGGTTCCCTA 
GCTGAGATTT TACTGAAGAA GAGTTTATTC AAGGACCAAA TGGAGCTGTT TCTACAAAAT 
CATGTATTTC CATTATTATT GTCTAACCTG GGATATCTTC GAGCTAGATC TTGCTGGGTA 
CTTCATGCAT TTAGTTCTTT GAAGTTCCAT AATGAGCTCA ATCTAAGAAA TGCCGTTGAA 
TTAGCGAAGA AGAGCCTGAT TGAAGATAAA GAGATGCCTG TCAAAGTTGA AGCTGCCCTT 
GCTCTTCAGT CTTTAATTTC TAACCAGATA CAAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IPO8 ( XM_017018691.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016874180.1 Homo sapiens importin 8 (IPO8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu83453
Clone ID Related Accession (Same CDS sequence)	XM_017018691.1 , XM_017018691.2
Accession Version	XM_017018691.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3063bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	importin-8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGATAC TGCTTTATCT AAGACACATC AAATCCTACA AGATTATCAA TTTTGCCCCC 
AGTTTACTTC GGATTATAGT CTCTGACCAT GTGGAATTCC CAGTACGACA GGCAGCTGCC 
ATTTACCTGA AGAACATGGT GACACAATAC TGGCCAGATC GAGAACCTCC ACCAGGAGAA 
GCAATATTTC CATTCAACAT TCACGAAAAC GATCGCCAGC AAATACGTGA TAACATTGTG 
GAAGGAATAA TTCGGTCTCC AGATTTAGTG AGAGTCCAAT TAACAATGTG TCTCCGTGCC 
ATCATAAAAC ATGATTTTCC TGGTCACTGG CCAGGAGTGG TCGACAAGAT AGACTATTAC 
TTGCAATCAC AGAGCAGTGC AAGCTGGCTT GGCAGTTTAT TATGCCTGTA TCAACTGGTG 
AAGACATATG AATATAAGAA AGCAGAAGAG AGAGAACCTC TTATAATAGC AATGCAGATA 
TTCCTGCCTC GTATTCAGCA ACAAATTGTT CAGCTCCTTC CTGATTCCTC CTATTATTCT 
GTATTACTGC AGAAACAAAT TCTGAAAATC TTTTATGCAC TTGTTCAGTA TGCATTGCCT 
CTTCAGCTAG TGAATAACCA AACCATGACA ACATGGATGG AGATCTTCCG AACTATTATC 
GACAGGACCG TTCCTCCTGA GACTCTGCAC ATTGATGAGG ATGATAGACC AGAACTGGTA 
TGGTGGAAGT GTAAGAAGTG GGCACTGCAT ATTGTAGCTC GGCTCTTTGA ACGATATGGA 
AGCCCAGGAA ATGTCACAAA AGAATACTTT GAATTTTCTG AATTCTTTTT GAAAACCTAT 
GCAGTGGGCA TTCAGCAGGT GCTACTAAAA ATTTTAGATC AATATAGACA GAAAGAATAT 
GTAGCTCCCC GTGTTCTTCA GCAAGCATTC AACTATCTCA ACCAAGGGGT GGTTCATTCT 
ATAACCTGGA AGCAGATGAA GCCACACATA CAGAATATCT CTGAAGATGT GATTTTTTCT 
GTGATGTGTT ATAAAGATGA GGATGAAGAG CTGTGGCAAG AAGATCCATA TGAGTATATA 
AGGATGAAAT TTGATATTTT TGAAGATTAT GCTTCTCCCA CCACAGCAGC CCAGACTCTC 
TTATATACTG CTGCAAAGAA AAGAAAAGAG GTGTTGCCAA AAATGATGGC ATTCTGTTAT 
CAAATCCTGA CAGACCCGAA CTTTGACCCT AGGAAGAAAG ATGGAGCCCT GCATGTGATT 
GGTTCCCTAG CTGAGATTTT ACTGAAGAAG AGTTTATTCA AGGACCAAAT GGAGCTGTTT 
CTACAAAATC ATGTATTTCC ATTATTATTG TCTAACCTGG GATATCTTCG AGCTAGATCT 
TGCTGGGTAC TTCATGCATT TAGTTCTTTG AAGTTCCATA ATGAGCTCAA TCTAAGAAAT 
GCCGTTGAAT TAGCGAAGAA GAGCCTGATT GAAGATAAAG AGATGCCTGT CAAAGTTGAA 
GCTGCCCTTG CTCTTCAGTC TTTAATTTCT AACCAGATAC AAGCTAAGGA ATATATGAAG 
CCACATGTGA GGCCTATTAT GCAGGAACTG TTGCACATTG TTAGAGAGAC AGAAAATGAT 
GATGTTACTA ATGTCATCCA GAAGATGATA TGTGAATACA GTCAAGAGGT AGCCTCAATT 
GCTGTTGATA TGACCCAACA CTTGGCTGAG ATATTTGGCA AAGTTCTTCA AAGTGATGAA 
TATGAAGAAG TTGAAGACAA AACAGTAATG GCTATGGGAA TTTTACATAC CATTGATACT 
ATCTTAACAG TTGTAGAAGA TCATAAAGAG ATTACCCAGC AGTTAGAGAA TATCTGTCTA 
CGGATCATTG ATCTTGTTCT GCAGAAACAT GTAATTGAAT TCTATGAAGA AATTCTTTCC 
CTGGCATACA GTTTAACCTG CCACAGTATT TCCCCTCAAA TGTGGCAGCT TCTAGGTATA 
CTATATGAAG TGTTTCAGCA GGATTGCTTT GAATACTTTA CAGACATGAT GCCTCTCCTG 
CATAATTATG TGACAATAGA TACAGATACC TTACTATCAA ATGCAAAACA TTTAGAAATT 
CTTTTTACAA TGTGTAGGAA GGTACTATGT GGAGATGCAG GAGAAGATGC AGAGTGTCAT 
GCAGCTAAAC TTCTGGAAGT CATCATTCTT CAGTGCAAAG GAAGGGGAAT TGATCAGTGC 
ATTCCACTCT TCGTTCAACT TGTTTTGGAG AGATTAACTC GAGGGGTCAA AACTAGTGAG 
CTTCGTACTA TGTGTCTTCA GGTTGCAATT GCTGCCTTGT ACTACAACCC TGATTTGCTG 
CTACATACTT TAGAACGAAT TCAGTTGCCT CACAACCCTG GACCTATCAC TGTACAGTTT 
ATAAATCAAT GGATGAATGA TACAGATTGT TTTCTTGGGC ATCATGACCG GAAGATGTGT 
ATAATAGGAC TGAGTATCCT TTTGGAATTG CAAAATCGAC CTCCTGCAGT AGATGCTGTG 
GTGGGACAGA TTGTTCCCTC AATTCTTTTC CTTTTCCTTG GCCTAAAGCA GGTCTGTGCT 
ACTAGACAAC TGGTAAACCG GGAAGATCGT TCAAAAGCAG AGAAAGCTGA TATGGAAGAA 
AATGAGGAGA TTTCAAGTGA TGAAGAGGAG ACAAATGTAA CTGCTCAAGC AATGCAGTCA 
AATAATGGAA GAGGTGAAGA TGAGGAGGAG GAAGATGATG ACTGGGATGA AGAAGTATTG 
GAAGAAACCG CGCTTGAGGG GTTCAGTACT CCACTTGACC TTGACAATAG TGTGGATGAA 
TATCAGTTTT TTACACAAGC TCTGATAACT GTGCAGAGTC GAGATGCAGC CTGGTACCAG 
CTGCTGATGG CACCACTCAG CGAGGATCAG AGGACAGCAC TGCAGGAGGT GTACACACTG 
GCAGAGCACC GACGGACGGT GGCAGAGGCA AAGAAGAAGA TTGAACAACA GGGAGGCTTC 
ACCTTTGAAA ACAAAGGAGT CCTCTCCGCA TTTAATTTTG GGACTGTGCC CAGCAACAAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016874180.1
CDS	297..3359
Translation	MVILLYLRHIKSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRAIIKHDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLPRIQQQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRTVPPETLHIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVGIQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVIFSVMCYKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQILTDPNFDPRKKDGALHVIGSLAEILLKKSLFKDQMELFLQNHVFPLLLSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPVKVEAALALQSLISNQIQAKEYMKPHVRPIMQELLHIVRETENDDVTNVIQKMICEYSQEVASIAVDMTQHLAEIFGKVLQSDEYEEVEDKTVMAMGILHTIDTILTVVEDHKEITQQLENICLRIIDLVLQKHVIEFYEEILSLAYSLTCHSISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTIDTDTLLSNAKHLEILFTMCRKVLCGDAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLTRGVKTSELRTMCLQVAIAALYYNPDLLLHTLERIQLPHNPGPITVQFINQWMNDTDCFLGHHDRKMCIIGLSILLELQNRPPAVDAVVGQIVPSILFLFLGLKQVCATRQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETALEGFSTPLDLDNSVDEYQFFTQALITVQSRDAAWYQLLMAPLSEDQRTALQEVYTLAEHRRTVAEAKKKIEQQGGFTFENKGVLSAFNFGTVPSNN

Target ORF information:

RefSeq Version	XM_017018691.1
Organism	Homo sapiens(human)
Definition	Homo sapiens importin 8 (IPO8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017018691.1

ORF Insert Sequence:

ATGGTGATAC TGCTTTATCT AAGACACATC AAATCCTACA AGATTATCAA TTTTGCCCCC 
AGTTTACTTC GGATTATAGT CTCTGACCAT GTGGAATTCC CAGTACGACA GGCAGCTGCC 
ATTTACCTGA AGAACATGGT GACACAATAC TGGCCAGATC GAGAACCTCC ACCAGGAGAA 
GCAATATTTC CATTCAACAT TCACGAAAAC GATCGCCAGC AAATACGTGA TAACATTGTG 
GAAGGAATAA TTCGGTCTCC AGATTTAGTG AGAGTCCAAT TAACAATGTG TCTCCGTGCC 
ATCATAAAAC ATGATTTTCC TGGTCACTGG CCAGGAGTGG TCGACAAGAT AGACTATTAC 
TTGCAATCAC AGAGCAGTGC AAGCTGGCTT GGCAGTTTAT TATGCCTGTA TCAACTGGTG 
AAGACATATG AATATAAGAA AGCAGAAGAG AGAGAACCTC TTATAATAGC AATGCAGATA 
TTCCTGCCTC GTATTCAGCA ACAAATTGTT CAGCTCCTTC CTGATTCCTC CTATTATTCT 
GTATTACTGC AGAAACAAAT TCTGAAAATC TTTTATGCAC TTGTTCAGTA TGCATTGCCT 
CTTCAGCTAG TGAATAACCA AACCATGACA ACATGGATGG AGATCTTCCG AACTATTATC 
GACAGGACCG TTCCTCCTGA GACTCTGCAC ATTGATGAGG ATGATAGACC AGAACTGGTA 
TGGTGGAAGT GTAAGAAGTG GGCACTGCAT ATTGTAGCTC GGCTCTTTGA ACGATATGGA 
AGCCCAGGAA ATGTCACAAA AGAATACTTT GAATTTTCTG AATTCTTTTT GAAAACCTAT 
GCAGTGGGCA TTCAGCAGGT GCTACTAAAA ATTTTAGATC AATATAGACA GAAAGAATAT 
GTAGCTCCCC GTGTTCTTCA GCAAGCATTC AACTATCTCA ACCAAGGGGT GGTTCATTCT 
ATAACCTGGA AGCAGATGAA GCCACACATA CAGAATATCT CTGAAGATGT GATTTTTTCT 
GTGATGTGTT ATAAAGATGA GGATGAAGAG CTGTGGCAAG AAGATCCATA TGAGTATATA 
AGGATGAAAT TTGATATTTT TGAAGATTAT GCTTCTCCCA CCACAGCAGC CCAGACTCTC 
TTATATACTG CTGCAAAGAA AAGAAAAGAG GTGTTGCCAA AAATGATGGC ATTCTGTTAT 
CAAATCCTGA CAGACCCGAA CTTTGACCCT AGGAAGAAAG ATGGAGCCCT GCATGTGATT 
GGTTCCCTAG CTGAGATTTT ACTGAAGAAG AGTTTATTCA AGGACCAAAT GGAGCTGTTT 
CTACAAAATC ATGTATTTCC ATTATTATTG TCTAACCTGG GATATCTTCG AGCTAGATCT 
TGCTGGGTAC TTCATGCATT TAGTTCTTTG AAGTTCCATA ATGAGCTCAA TCTAAGAAAT 
GCCGTTGAAT TAGCGAAGAA GAGCCTGATT GAAGATAAAG AGATGCCTGT CAAAGTTGAA 
GCTGCCCTTG CTCTTCAGTC TTTAATTTCT AACCAGATAC AAGCTAAGGA ATATATGAAG 
CCACATGTGA GGCCTATTAT GCAGGAACTG TTGCACATTG TTAGAGAGAC AGAAAATGAT 
GATGTTACTA ATGTCATCCA GAAGATGATA TGTGAATACA GTCAAGAGGT AGCCTCAATT 
GCTGTTGATA TGACCCAACA CTTGGCTGAG ATATTTGGCA AAGTTCTTCA AAGTGATGAA 
TATGAAGAAG TTGAAGACAA AACAGTAATG GCTATGGGAA TTTTACATAC CATTGATACT 
ATCTTAACAG TTGTAGAAGA TCATAAAGAG ATTACCCAGC AGTTAGAGAA TATCTGTCTA 
CGGATCATTG ATCTTGTTCT GCAGAAACAT GTAATTGAAT TCTATGAAGA AATTCTTTCC 
CTGGCATACA GTTTAACCTG CCACAGTATT TCCCCTCAAA TGTGGCAGCT TCTAGGTATA 
CTATATGAAG TGTTTCAGCA GGATTGCTTT GAATACTTTA CAGACATGAT GCCTCTCCTG 
CATAATTATG TGACAATAGA TACAGATACC TTACTATCAA ATGCAAAACA TTTAGAAATT 
CTTTTTACAA TGTGTAGGAA GGTACTATGT GGAGATGCAG GAGAAGATGC AGAGTGTCAT 
GCAGCTAAAC TTCTGGAAGT CATCATTCTT CAGTGCAAAG GAAGGGGAAT TGATCAGTGC 
ATTCCACTCT TCGTTCAACT TGTTTTGGAG AGATTAACTC GAGGGGTCAA AACTAGTGAG 
CTTCGTACTA TGTGTCTTCA GGTTGCAATT GCTGCCTTGT ACTACAACCC TGATTTGCTG 
CTACATACTT TAGAACGAAT TCAGTTGCCT CACAACCCTG GACCTATCAC TGTACAGTTT 
ATAAATCAAT GGATGAATGA TACAGATTGT TTTCTTGGGC ATCATGACCG GAAGATGTGT 
ATAATAGGAC TGAGTATCCT TTTGGAATTG CAAAATCGAC CTCCTGCAGT AGATGCTGTG 
GTGGGACAGA TTGTTCCCTC AATTCTTTTC CTTTTCCTTG GCCTAAAGCA GGTCTGTGCT 
ACTAGACAAC TGGTAAACCG GGAAGATCGT TCAAAAGCAG AGAAAGCTGA TATGGAAGAA 
AATGAGGAGA TTTCAAGTGA TGAAGAGGAG ACAAATGTAA CTGCTCAAGC AATGCAGTCA 
AATAATGGAA GAGGTGAAGA TGAGGAGGAG GAAGATGATG ACTGGGATGA AGAAGTATTG 
GAAGAAACCG CGCTTGAGGG GTTCAGTACT CCACTTGACC TTGACAATAG TGTGGATGAA 
TATCAGTTTT TTACACAAGC TCTGATAACT GTGCAGAGTC GAGATGCAGC CTGGTACCAG 
CTGCTGATGG CACCACTCAG CGAGGATCAG AGGACAGCAC TGCAGGAGGT GTACACACTG 
GCAGAGCACC GACGGACGGT GGCAGAGGCA AAGAAGAAGA TTGAACAACA GGGAGGCTTC 
ACCTTTGAAA ACAAAGGAGT CCTCTCCGCA TTTAATTTTG GGACTGTGCC CAGCAACAAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IPO8 ( XM_017018691.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016874180.1 Homo sapiens importin 8 (IPO8), transcript variant X1, mRNA.

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CloneID	OHu83453
Clone ID Related Accession (Same CDS sequence)	XM_017018691.1 , XM_017018691.2
Accession Version	XM_017018691.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3063bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	importin-8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017018691.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGATAC TGCTTTATCT AAGACACATC AAATCCTACA AGATTATCAA TTTTGCCCCC 
AGTTTACTTC GGATTATAGT CTCTGACCAT GTGGAATTCC CAGTACGACA GGCAGCTGCC 
ATTTACCTGA AGAACATGGT GACACAATAC TGGCCAGATC GAGAACCTCC ACCAGGAGAA 
GCAATATTTC CATTCAACAT TCACGAAAAC GATCGCCAGC AAATACGTGA TAACATTGTG 
GAAGGAATAA TTCGGTCTCC AGATTTAGTG AGAGTCCAAT TAACAATGTG TCTCCGTGCC 
ATCATAAAAC ATGATTTTCC TGGTCACTGG CCAGGAGTGG TCGACAAGAT AGACTATTAC 
TTGCAATCAC AGAGCAGTGC AAGCTGGCTT GGCAGTTTAT TATGCCTGTA TCAACTGGTG 
AAGACATATG AATATAAGAA AGCAGAAGAG AGAGAACCTC TTATAATAGC AATGCAGATA 
TTCCTGCCTC GTATTCAGCA ACAAATTGTT CAGCTCCTTC CTGATTCCTC CTATTATTCT 
GTATTACTGC AGAAACAAAT TCTGAAAATC TTTTATGCAC TTGTTCAGTA TGCATTGCCT 
CTTCAGCTAG TGAATAACCA AACCATGACA ACATGGATGG AGATCTTCCG AACTATTATC 
GACAGGACCG TTCCTCCTGA GACTCTGCAC ATTGATGAGG ATGATAGACC AGAACTGGTA 
TGGTGGAAGT GTAAGAAGTG GGCACTGCAT ATTGTAGCTC GGCTCTTTGA ACGATATGGA 
AGCCCAGGAA ATGTCACAAA AGAATACTTT GAATTTTCTG AATTCTTTTT GAAAACCTAT 
GCAGTGGGCA TTCAGCAGGT GCTACTAAAA ATTTTAGATC AATATAGACA GAAAGAATAT 
GTAGCTCCCC GTGTTCTTCA GCAAGCATTC AACTATCTCA ACCAAGGGGT GGTTCATTCT 
ATAACCTGGA AGCAGATGAA GCCACACATA CAGAATATCT CTGAAGATGT GATTTTTTCT 
GTGATGTGTT ATAAAGATGA GGATGAAGAG CTGTGGCAAG AAGATCCATA TGAGTATATA 
AGGATGAAAT TTGATATTTT TGAAGATTAT GCTTCTCCCA CCACAGCAGC CCAGACTCTC 
TTATATACTG CTGCAAAGAA AAGAAAAGAG GTGTTGCCAA AAATGATGGC ATTCTGTTAT 
CAAATCCTGA CAGACCCGAA CTTTGACCCT AGGAAGAAAG ATGGAGCCCT GCATGTGATT 
GGTTCCCTAG CTGAGATTTT ACTGAAGAAG AGTTTATTCA AGGACCAAAT GGAGCTGTTT 
CTACAAAATC ATGTATTTCC ATTATTATTG TCTAACCTGG GATATCTTCG AGCTAGATCT 
TGCTGGGTAC TTCATGCATT TAGTTCTTTG AAGTTCCATA ATGAGCTCAA TCTAAGAAAT 
GCCGTTGAAT TAGCGAAGAA GAGCCTGATT GAAGATAAAG AGATGCCTGT CAAAGTTGAA 
GCTGCCCTTG CTCTTCAGTC TTTAATTTCT AACCAGATAC AAGCTAAGGA ATATATGAAG 
CCACATGTGA GGCCTATTAT GCAGGAACTG TTGCACATTG TTAGAGAGAC AGAAAATGAT 
GATGTTACTA ATGTCATCCA GAAGATGATA TGTGAATACA GTCAAGAGGT AGCCTCAATT 
GCTGTTGATA TGACCCAACA CTTGGCTGAG ATATTTGGCA AAGTTCTTCA AAGTGATGAA 
TATGAAGAAG TTGAAGACAA AACAGTAATG GCTATGGGAA TTTTACATAC CATTGATACT 
ATCTTAACAG TTGTAGAAGA TCATAAAGAG ATTACCCAGC AGTTAGAGAA TATCTGTCTA 
CGGATCATTG ATCTTGTTCT GCAGAAACAT GTAATTGAAT TCTATGAAGA AATTCTTTCC 
CTGGCATACA GTTTAACCTG CCACAGTATT TCCCCTCAAA TGTGGCAGCT TCTAGGTATA 
CTATATGAAG TGTTTCAGCA GGATTGCTTT GAATACTTTA CAGACATGAT GCCTCTCCTG 
CATAATTATG TGACAATAGA TACAGATACC TTACTATCAA ATGCAAAACA TTTAGAAATT 
CTTTTTACAA TGTGTAGGAA GGTACTATGT GGAGATGCAG GAGAAGATGC AGAGTGTCAT 
GCAGCTAAAC TTCTGGAAGT CATCATTCTT CAGTGCAAAG GAAGGGGAAT TGATCAGTGC 
ATTCCACTCT TCGTTCAACT TGTTTTGGAG AGATTAACTC GAGGGGTCAA AACTAGTGAG 
CTTCGTACTA TGTGTCTTCA GGTTGCAATT GCTGCCTTGT ACTACAACCC TGATTTGCTG 
CTACATACTT TAGAACGAAT TCAGTTGCCT CACAACCCTG GACCTATCAC TGTACAGTTT 
ATAAATCAAT GGATGAATGA TACAGATTGT TTTCTTGGGC ATCATGACCG GAAGATGTGT 
ATAATAGGAC TGAGTATCCT TTTGGAATTG CAAAATCGAC CTCCTGCAGT AGATGCTGTG 
GTGGGACAGA TTGTTCCCTC AATTCTTTTC CTTTTCCTTG GCCTAAAGCA GGTCTGTGCT 
ACTAGACAAC TGGTAAACCG GGAAGATCGT TCAAAAGCAG AGAAAGCTGA TATGGAAGAA 
AATGAGGAGA TTTCAAGTGA TGAAGAGGAG ACAAATGTAA CTGCTCAAGC AATGCAGTCA 
AATAATGGAA GAGGTGAAGA TGAGGAGGAG GAAGATGATG ACTGGGATGA AGAAGTATTG 
GAAGAAACCG CGCTTGAGGG GTTCAGTACT CCACTTGACC TTGACAATAG TGTGGATGAA 
TATCAGTTTT TTACACAAGC TCTGATAACT GTGCAGAGTC GAGATGCAGC CTGGTACCAG 
CTGCTGATGG CACCACTCAG CGAGGATCAG AGGACAGCAC TGCAGGAGGT GTACACACTG 
GCAGAGCACC GACGGACGGT GGCAGAGGCA AAGAAGAAGA TTGAACAACA GGGAGGCTTC 
ACCTTTGAAA ACAAAGGAGT CCTCTCCGCA TTTAATTTTG GGACTGTGCC CAGCAACAAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016874180.1
CDS	298..3360
Translation	MVILLYLRHIKSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRAIIKHDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLPRIQQQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRTVPPETLHIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVGIQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVIFSVMCYKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQILTDPNFDPRKKDGALHVIGSLAEILLKKSLFKDQMELFLQNHVFPLLLSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPVKVEAALALQSLISNQIQAKEYMKPHVRPIMQELLHIVRETENDDVTNVIQKMICEYSQEVASIAVDMTQHLAEIFGKVLQSDEYEEVEDKTVMAMGILHTIDTILTVVEDHKEITQQLENICLRIIDLVLQKHVIEFYEEILSLAYSLTCHSISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTIDTDTLLSNAKHLEILFTMCRKVLCGDAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLTRGVKTSELRTMCLQVAIAALYYNPDLLLHTLERIQLPHNPGPITVQFINQWMNDTDCFLGHHDRKMCIIGLSILLELQNRPPAVDAVVGQIVPSILFLFLGLKQVCATRQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETALEGFSTPLDLDNSVDEYQFFTQALITVQSRDAAWYQLLMAPLSEDQRTALQEVYTLAEHRRTVAEAKKKIEQQGGFTFENKGVLSAFNFGTVPSNN

Target ORF information:

RefSeq Version	XM_017018691.2
Organism	Homo sapiens(human)
Definition	Homo sapiens importin 8 (IPO8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017018691.2

ORF Insert Sequence:

ATGGTGATAC TGCTTTATCT AAGACACATC AAATCCTACA AGATTATCAA TTTTGCCCCC 
AGTTTACTTC GGATTATAGT CTCTGACCAT GTGGAATTCC CAGTACGACA GGCAGCTGCC 
ATTTACCTGA AGAACATGGT GACACAATAC TGGCCAGATC GAGAACCTCC ACCAGGAGAA 
GCAATATTTC CATTCAACAT TCACGAAAAC GATCGCCAGC AAATACGTGA TAACATTGTG 
GAAGGAATAA TTCGGTCTCC AGATTTAGTG AGAGTCCAAT TAACAATGTG TCTCCGTGCC 
ATCATAAAAC ATGATTTTCC TGGTCACTGG CCAGGAGTGG TCGACAAGAT AGACTATTAC 
TTGCAATCAC AGAGCAGTGC AAGCTGGCTT GGCAGTTTAT TATGCCTGTA TCAACTGGTG 
AAGACATATG AATATAAGAA AGCAGAAGAG AGAGAACCTC TTATAATAGC AATGCAGATA 
TTCCTGCCTC GTATTCAGCA ACAAATTGTT CAGCTCCTTC CTGATTCCTC CTATTATTCT 
GTATTACTGC AGAAACAAAT TCTGAAAATC TTTTATGCAC TTGTTCAGTA TGCATTGCCT 
CTTCAGCTAG TGAATAACCA AACCATGACA ACATGGATGG AGATCTTCCG AACTATTATC 
GACAGGACCG TTCCTCCTGA GACTCTGCAC ATTGATGAGG ATGATAGACC AGAACTGGTA 
TGGTGGAAGT GTAAGAAGTG GGCACTGCAT ATTGTAGCTC GGCTCTTTGA ACGATATGGA 
AGCCCAGGAA ATGTCACAAA AGAATACTTT GAATTTTCTG AATTCTTTTT GAAAACCTAT 
GCAGTGGGCA TTCAGCAGGT GCTACTAAAA ATTTTAGATC AATATAGACA GAAAGAATAT 
GTAGCTCCCC GTGTTCTTCA GCAAGCATTC AACTATCTCA ACCAAGGGGT GGTTCATTCT 
ATAACCTGGA AGCAGATGAA GCCACACATA CAGAATATCT CTGAAGATGT GATTTTTTCT 
GTGATGTGTT ATAAAGATGA GGATGAAGAG CTGTGGCAAG AAGATCCATA TGAGTATATA 
AGGATGAAAT TTGATATTTT TGAAGATTAT GCTTCTCCCA CCACAGCAGC CCAGACTCTC 
TTATATACTG CTGCAAAGAA AAGAAAAGAG GTGTTGCCAA AAATGATGGC ATTCTGTTAT 
CAAATCCTGA CAGACCCGAA CTTTGACCCT AGGAAGAAAG ATGGAGCCCT GCATGTGATT 
GGTTCCCTAG CTGAGATTTT ACTGAAGAAG AGTTTATTCA AGGACCAAAT GGAGCTGTTT 
CTACAAAATC ATGTATTTCC ATTATTATTG TCTAACCTGG GATATCTTCG AGCTAGATCT 
TGCTGGGTAC TTCATGCATT TAGTTCTTTG AAGTTCCATA ATGAGCTCAA TCTAAGAAAT 
GCCGTTGAAT TAGCGAAGAA GAGCCTGATT GAAGATAAAG AGATGCCTGT CAAAGTTGAA 
GCTGCCCTTG CTCTTCAGTC TTTAATTTCT AACCAGATAC AAGCTAAGGA ATATATGAAG 
CCACATGTGA GGCCTATTAT GCAGGAACTG TTGCACATTG TTAGAGAGAC AGAAAATGAT 
GATGTTACTA ATGTCATCCA GAAGATGATA TGTGAATACA GTCAAGAGGT AGCCTCAATT 
GCTGTTGATA TGACCCAACA CTTGGCTGAG ATATTTGGCA AAGTTCTTCA AAGTGATGAA 
TATGAAGAAG TTGAAGACAA AACAGTAATG GCTATGGGAA TTTTACATAC CATTGATACT 
ATCTTAACAG TTGTAGAAGA TCATAAAGAG ATTACCCAGC AGTTAGAGAA TATCTGTCTA 
CGGATCATTG ATCTTGTTCT GCAGAAACAT GTAATTGAAT TCTATGAAGA AATTCTTTCC 
CTGGCATACA GTTTAACCTG CCACAGTATT TCCCCTCAAA TGTGGCAGCT TCTAGGTATA 
CTATATGAAG TGTTTCAGCA GGATTGCTTT GAATACTTTA CAGACATGAT GCCTCTCCTG 
CATAATTATG TGACAATAGA TACAGATACC TTACTATCAA ATGCAAAACA TTTAGAAATT 
CTTTTTACAA TGTGTAGGAA GGTACTATGT GGAGATGCAG GAGAAGATGC AGAGTGTCAT 
GCAGCTAAAC TTCTGGAAGT CATCATTCTT CAGTGCAAAG GAAGGGGAAT TGATCAGTGC 
ATTCCACTCT TCGTTCAACT TGTTTTGGAG AGATTAACTC GAGGGGTCAA AACTAGTGAG 
CTTCGTACTA TGTGTCTTCA GGTTGCAATT GCTGCCTTGT ACTACAACCC TGATTTGCTG 
CTACATACTT TAGAACGAAT TCAGTTGCCT CACAACCCTG GACCTATCAC TGTACAGTTT 
ATAAATCAAT GGATGAATGA TACAGATTGT TTTCTTGGGC ATCATGACCG GAAGATGTGT 
ATAATAGGAC TGAGTATCCT TTTGGAATTG CAAAATCGAC CTCCTGCAGT AGATGCTGTG 
GTGGGACAGA TTGTTCCCTC AATTCTTTTC CTTTTCCTTG GCCTAAAGCA GGTCTGTGCT 
ACTAGACAAC TGGTAAACCG GGAAGATCGT TCAAAAGCAG AGAAAGCTGA TATGGAAGAA 
AATGAGGAGA TTTCAAGTGA TGAAGAGGAG ACAAATGTAA CTGCTCAAGC AATGCAGTCA 
AATAATGGAA GAGGTGAAGA TGAGGAGGAG GAAGATGATG ACTGGGATGA AGAAGTATTG 
GAAGAAACCG CGCTTGAGGG GTTCAGTACT CCACTTGACC TTGACAATAG TGTGGATGAA 
TATCAGTTTT TTACACAAGC TCTGATAACT GTGCAGAGTC GAGATGCAGC CTGGTACCAG 
CTGCTGATGG CACCACTCAG CGAGGATCAG AGGACAGCAC TGCAGGAGGT GTACACACTG 
GCAGAGCACC GACGGACGGT GGCAGAGGCA AAGAAGAAGA TTGAACAACA GGGAGGCTTC 
ACCTTTGAAA ACAAAGGAGT CCTCTCCGCA TTTAATTTTG GGACTGTGCC CAGCAACAAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IPO8 ( NM_006390.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006381.2 Homo sapiens importin 8 (IPO8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu05483
Clone ID Related Accession (Same CDS sequence)	NM_006390.3 , NM_006390.4
Accession Version	NM_006390.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3114bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	importin-8 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB072643.1, DB088518.1, U77494.1, AK302260.1, DB067822.1, AK130090.1, EB387074.1, BG574795.1 and AA620453.1. On Jul 9, 2010 this sequence version replaced NM_006390.2. Transcript Variant: This variant (1) is the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.170067.1, SRR1660807.262017.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACCTCA ACCGGATCAT CCAGGCGCTG AAGGGCACCA TCGACCCGAA GTTGCGGATT 
GCAGCCGAGA ACGAGCTCAA CCAGTCCTAC AAGATTATCA ATTTTGCCCC CAGTTTACTT 
CGGATTATAG TCTCTGACCA TGTGGAATTC CCAGTACGAC AGGCAGCTGC CATTTACCTG 
AAGAACATGG TGACACAATA CTGGCCAGAT CGAGAACCTC CACCAGGAGA AGCAATATTT 
CCATTCAACA TTCACGAAAA CGATCGCCAG CAAATACGTG ATAACATTGT GGAAGGAATA 
ATTCGGTCTC CAGATTTAGT GAGAGTCCAA TTAACAATGT GTCTCCGTGC CATCATAAAA 
CATGATTTTC CTGGTCACTG GCCAGGAGTG GTCGACAAGA TAGACTATTA CTTGCAATCA 
CAGAGCAGTG CAAGCTGGCT TGGCAGTTTA TTATGCCTGT ATCAACTGGT GAAGACATAT 
GAATATAAGA AAGCAGAAGA GAGAGAACCT CTTATAATAG CAATGCAGAT ATTCCTGCCT 
CGTATTCAGC AACAAATTGT TCAGCTCCTT CCTGATTCCT CCTATTATTC TGTATTACTG 
CAGAAACAAA TTCTGAAAAT CTTTTATGCA CTTGTTCAGT ATGCATTGCC TCTTCAGCTA 
GTGAATAACC AAACCATGAC AACATGGATG GAGATCTTCC GAACTATTAT CGACAGGACC 
GTTCCTCCTG AGACTCTGCA CATTGATGAG GATGATAGAC CAGAACTGGT ATGGTGGAAG 
TGTAAGAAGT GGGCACTGCA TATTGTAGCT CGGCTCTTTG AACGATATGG AAGCCCAGGA 
AATGTCACAA AAGAATACTT TGAATTTTCT GAATTCTTTT TGAAAACCTA TGCAGTGGGC 
ATTCAGCAGG TGCTACTAAA AATTTTAGAT CAATATAGAC AGAAAGAATA TGTAGCTCCC 
CGTGTTCTTC AGCAAGCATT CAACTATCTC AACCAAGGGG TGGTTCATTC TATAACCTGG 
AAGCAGATGA AGCCACACAT ACAGAATATC TCTGAAGATG TGATTTTTTC TGTGATGTGT 
TATAAAGATG AGGATGAAGA GCTGTGGCAA GAAGATCCAT ATGAGTATAT AAGGATGAAA 
TTTGATATTT TTGAAGATTA TGCTTCTCCC ACCACAGCAG CCCAGACTCT CTTATATACT 
GCTGCAAAGA AAAGAAAAGA GGTGTTGCCA AAAATGATGG CATTCTGTTA TCAAATCCTG 
ACAGACCCGA ACTTTGACCC TAGGAAGAAA GATGGAGCCC TGCATGTGAT TGGTTCCCTA 
GCTGAGATTT TACTGAAGAA GAGTTTATTC AAGGACCAAA TGGAGCTGTT TCTACAAAAT 
CATGTATTTC CATTATTATT GTCTAACCTG GGATATCTTC GAGCTAGATC TTGCTGGGTA 
CTTCATGCAT TTAGTTCTTT GAAGTTCCAT AATGAGCTCA ATCTAAGAAA TGCCGTTGAA 
TTAGCGAAGA AGAGCCTGAT TGAAGATAAA GAGATGCCTG TCAAAGTTGA AGCTGCCCTT 
GCTCTTCAGT CTTTAATTTC TAACCAGATA CAAGCTAAGG AATATATGAA GCCACATGTG 
AGGCCTATTA TGCAGGAACT GTTGCACATT GTTAGAGAGA CAGAAAATGA TGATGTTACT 
AATGTCATCC AGAAGATGAT ATGTGAATAC AGTCAAGAGG TAGCCTCAAT TGCTGTTGAT 
ATGACCCAAC ACTTGGCTGA GATATTTGGC AAAGTTCTTC AAAGTGATGA ATATGAAGAA 
GTTGAAGACA AAACAGTAAT GGCTATGGGA ATTTTACATA CCATTGATAC TATCTTAACA 
GTTGTAGAAG ATCATAAAGA GATTACCCAG CAGTTAGAGA ATATCTGTCT ACGGATCATT 
GATCTTGTTC TGCAGAAACA TGTAATTGAA TTCTATGAAG AAATTCTTTC CCTGGCATAC 
AGTTTAACCT GCCACAGTAT TTCCCCTCAA ATGTGGCAGC TTCTAGGTAT ACTATATGAA 
GTGTTTCAGC AGGATTGCTT TGAATACTTT ACAGACATGA TGCCTCTCCT GCATAATTAT 
GTGACAATAG ATACAGATAC CTTACTATCA AATGCAAAAC ATTTAGAAAT TCTTTTTACA 
ATGTGTAGGA AGGTACTATG TGGAGATGCA GGAGAAGATG CAGAGTGTCA TGCAGCTAAA 
CTTCTGGAAG TCATCATTCT TCAGTGCAAA GGAAGGGGAA TTGATCAGTG CATTCCACTC 
TTCGTTCAAC TTGTTTTGGA GAGATTAACT CGAGGGGTCA AAACTAGTGA GCTTCGTACT 
ATGTGTCTTC AGGTTGCAAT TGCTGCCTTG TACTACAACC CTGATTTGCT GCTACATACT 
TTAGAACGAA TTCAGTTGCC TCACAACCCT GGACCTATCA CTGTACAGTT TATAAATCAA 
TGGATGAATG ATACAGATTG TTTTCTTGGG CATCATGACC GGAAGATGTG TATAATAGGA 
CTGAGTATCC TTTTGGAATT GCAAAATCGA CCTCCTGCAG TAGATGCTGT GGTGGGACAG 
ATTGTTCCCT CAATTCTTTT CCTTTTCCTT GGCCTAAAGC AGGTCTGTGC TACTAGACAA 
CTGGTAAACC GGGAAGATCG TTCAAAAGCA GAGAAAGCTG ATATGGAAGA AAATGAGGAG 
ATTTCAAGTG ATGAAGAGGA GACAAATGTA ACTGCTCAAG CAATGCAGTC AAATAATGGA 
AGAGGTGAAG ATGAGGAGGA GGAAGATGAT GACTGGGATG AAGAAGTATT GGAAGAAACC 
GCGCTTGAGG GGTTCAGTAC TCCACTTGAC CTTGACAATA GTGTGGATGA ATATCAGTTT 
TTTACACAAG CTCTGATAAC TGTGCAGAGT CGAGATGCAG CCTGGTACCA GCTGCTGATG 
GCACCACTCA GCGAGGATCA GAGGACAGCA CTGCAGGAGG TGTACACACT GGCAGAGCAC 
CGACGGACGG TGGCAGAGGC AAAGAAGAAG ATTGAACAAC AGGGAGGCTT CACCTTTGAA 
AACAAAGGAG TCCTCTCCGC ATTTAATTTT GGGACTGTGC CCAGCAACAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006381.2
CDS	349..3462
Translation	MDLNRIIQALKGTIDPKLRIAAENELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRAIIKHDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLPRIQQQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRTVPPETLHIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVGIQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVIFSVMCYKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQILTDPNFDPRKKDGALHVIGSLAEILLKKSLFKDQMELFLQNHVFPLLLSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPVKVEAALALQSLISNQIQAKEYMKPHVRPIMQELLHIVRETENDDVTNVIQKMICEYSQEVASIAVDMTQHLAEIFGKVLQSDEYEEVEDKTVMAMGILHTIDTILTVVEDHKEITQQLENICLRIIDLVLQKHVIEFYEEILSLAYSLTCHSISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTIDTDTLLSNAKHLEILFTMCRKVLCGDAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLTRGVKTSELRTMCLQVAIAALYYNPDLLLHTLERIQLPHNPGPITVQFINQWMNDTDCFLGHHDRKMCIIGLSILLELQNRPPAVDAVVGQIVPSILFLFLGLKQVCATRQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETALEGFSTPLDLDNSVDEYQFFTQALITVQSRDAAWYQLLMAPLSEDQRTALQEVYTLAEHRRTVAEAKKKIEQQGGFTFENKGVLSAFNFGTVPSNN

Target ORF information:

RefSeq Version	NM_006390.3
Organism	Homo sapiens(human)
Definition	Homo sapiens importin 8 (IPO8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006390.3

ORF Insert Sequence:

ATGGACCTCA ACCGGATCAT CCAGGCGCTG AAGGGCACCA TCGACCCGAA GTTGCGGATT 
GCAGCCGAGA ACGAGCTCAA CCAGTCCTAC AAGATTATCA ATTTTGCCCC CAGTTTACTT 
CGGATTATAG TCTCTGACCA TGTGGAATTC CCAGTACGAC AGGCAGCTGC CATTTACCTG 
AAGAACATGG TGACACAATA CTGGCCAGAT CGAGAACCTC CACCAGGAGA AGCAATATTT 
CCATTCAACA TTCACGAAAA CGATCGCCAG CAAATACGTG ATAACATTGT GGAAGGAATA 
ATTCGGTCTC CAGATTTAGT GAGAGTCCAA TTAACAATGT GTCTCCGTGC CATCATAAAA 
CATGATTTTC CTGGTCACTG GCCAGGAGTG GTCGACAAGA TAGACTATTA CTTGCAATCA 
CAGAGCAGTG CAAGCTGGCT TGGCAGTTTA TTATGCCTGT ATCAACTGGT GAAGACATAT 
GAATATAAGA AAGCAGAAGA GAGAGAACCT CTTATAATAG CAATGCAGAT ATTCCTGCCT 
CGTATTCAGC AACAAATTGT TCAGCTCCTT CCTGATTCCT CCTATTATTC TGTATTACTG 
CAGAAACAAA TTCTGAAAAT CTTTTATGCA CTTGTTCAGT ATGCATTGCC TCTTCAGCTA 
GTGAATAACC AAACCATGAC AACATGGATG GAGATCTTCC GAACTATTAT CGACAGGACC 
GTTCCTCCTG AGACTCTGCA CATTGATGAG GATGATAGAC CAGAACTGGT ATGGTGGAAG 
TGTAAGAAGT GGGCACTGCA TATTGTAGCT CGGCTCTTTG AACGATATGG AAGCCCAGGA 
AATGTCACAA AAGAATACTT TGAATTTTCT GAATTCTTTT TGAAAACCTA TGCAGTGGGC 
ATTCAGCAGG TGCTACTAAA AATTTTAGAT CAATATAGAC AGAAAGAATA TGTAGCTCCC 
CGTGTTCTTC AGCAAGCATT CAACTATCTC AACCAAGGGG TGGTTCATTC TATAACCTGG 
AAGCAGATGA AGCCACACAT ACAGAATATC TCTGAAGATG TGATTTTTTC TGTGATGTGT 
TATAAAGATG AGGATGAAGA GCTGTGGCAA GAAGATCCAT ATGAGTATAT AAGGATGAAA 
TTTGATATTT TTGAAGATTA TGCTTCTCCC ACCACAGCAG CCCAGACTCT CTTATATACT 
GCTGCAAAGA AAAGAAAAGA GGTGTTGCCA AAAATGATGG CATTCTGTTA TCAAATCCTG 
ACAGACCCGA ACTTTGACCC TAGGAAGAAA GATGGAGCCC TGCATGTGAT TGGTTCCCTA 
GCTGAGATTT TACTGAAGAA GAGTTTATTC AAGGACCAAA TGGAGCTGTT TCTACAAAAT 
CATGTATTTC CATTATTATT GTCTAACCTG GGATATCTTC GAGCTAGATC TTGCTGGGTA 
CTTCATGCAT TTAGTTCTTT GAAGTTCCAT AATGAGCTCA ATCTAAGAAA TGCCGTTGAA 
TTAGCGAAGA AGAGCCTGAT TGAAGATAAA GAGATGCCTG TCAAAGTTGA AGCTGCCCTT 
GCTCTTCAGT CTTTAATTTC TAACCAGATA CAAGCTAAGG AATATATGAA GCCACATGTG 
AGGCCTATTA TGCAGGAACT GTTGCACATT GTTAGAGAGA CAGAAAATGA TGATGTTACT 
AATGTCATCC AGAAGATGAT ATGTGAATAC AGTCAAGAGG TAGCCTCAAT TGCTGTTGAT 
ATGACCCAAC ACTTGGCTGA GATATTTGGC AAAGTTCTTC AAAGTGATGA ATATGAAGAA 
GTTGAAGACA AAACAGTAAT GGCTATGGGA ATTTTACATA CCATTGATAC TATCTTAACA 
GTTGTAGAAG ATCATAAAGA GATTACCCAG CAGTTAGAGA ATATCTGTCT ACGGATCATT 
GATCTTGTTC TGCAGAAACA TGTAATTGAA TTCTATGAAG AAATTCTTTC CCTGGCATAC 
AGTTTAACCT GCCACAGTAT TTCCCCTCAA ATGTGGCAGC TTCTAGGTAT ACTATATGAA 
GTGTTTCAGC AGGATTGCTT TGAATACTTT ACAGACATGA TGCCTCTCCT GCATAATTAT 
GTGACAATAG ATACAGATAC CTTACTATCA AATGCAAAAC ATTTAGAAAT TCTTTTTACA 
ATGTGTAGGA AGGTACTATG TGGAGATGCA GGAGAAGATG CAGAGTGTCA TGCAGCTAAA 
CTTCTGGAAG TCATCATTCT TCAGTGCAAA GGAAGGGGAA TTGATCAGTG CATTCCACTC 
TTCGTTCAAC TTGTTTTGGA GAGATTAACT CGAGGGGTCA AAACTAGTGA GCTTCGTACT 
ATGTGTCTTC AGGTTGCAAT TGCTGCCTTG TACTACAACC CTGATTTGCT GCTACATACT 
TTAGAACGAA TTCAGTTGCC TCACAACCCT GGACCTATCA CTGTACAGTT TATAAATCAA 
TGGATGAATG ATACAGATTG TTTTCTTGGG CATCATGACC GGAAGATGTG TATAATAGGA 
CTGAGTATCC TTTTGGAATT GCAAAATCGA CCTCCTGCAG TAGATGCTGT GGTGGGACAG 
ATTGTTCCCT CAATTCTTTT CCTTTTCCTT GGCCTAAAGC AGGTCTGTGC TACTAGACAA 
CTGGTAAACC GGGAAGATCG TTCAAAAGCA GAGAAAGCTG ATATGGAAGA AAATGAGGAG 
ATTTCAAGTG ATGAAGAGGA GACAAATGTA ACTGCTCAAG CAATGCAGTC AAATAATGGA 
AGAGGTGAAG ATGAGGAGGA GGAAGATGAT GACTGGGATG AAGAAGTATT GGAAGAAACC 
GCGCTTGAGG GGTTCAGTAC TCCACTTGAC CTTGACAATA GTGTGGATGA ATATCAGTTT 
TTTACACAAG CTCTGATAAC TGTGCAGAGT CGAGATGCAG CCTGGTACCA GCTGCTGATG 
GCACCACTCA GCGAGGATCA GAGGACAGCA CTGCAGGAGG TGTACACACT GGCAGAGCAC 
CGACGGACGG TGGCAGAGGC AAAGAAGAAG ATTGAACAAC AGGGAGGCTT CACCTTTGAA 
AACAAAGGAG TCCTCTCCGC ATTTAATTTT GGGACTGTGC CCAGCAACAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IPO8 ( NM_006390.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006381.2 Homo sapiens importin 8 (IPO8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu05483
Clone ID Related Accession (Same CDS sequence)	NM_006390.3 , NM_006390.4
Accession Version	NM_006390.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3114bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	importin-8 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB072643.1, DB088518.1, U77494.1, AK302260.1, DB067822.1, AK130090.1, EB387074.1 and BG574795.1. On Nov 23, 2018 this sequence version replaced NM_006390.3. Transcript Variant: This variant (1) is the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.170067.1, SRR1660807.262017.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000256079.9/ ENSP00000256079.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGACCTCA ACCGGATCAT CCAGGCGCTG AAGGGCACCA TCGACCCGAA GTTGCGGATT 
GCAGCCGAGA ACGAGCTCAA CCAGTCCTAC AAGATTATCA ATTTTGCCCC CAGTTTACTT 
CGGATTATAG TCTCTGACCA TGTGGAATTC CCAGTACGAC AGGCAGCTGC CATTTACCTG 
AAGAACATGG TGACACAATA CTGGCCAGAT CGAGAACCTC CACCAGGAGA AGCAATATTT 
CCATTCAACA TTCACGAAAA CGATCGCCAG CAAATACGTG ATAACATTGT GGAAGGAATA 
ATTCGGTCTC CAGATTTAGT GAGAGTCCAA TTAACAATGT GTCTCCGTGC CATCATAAAA 
CATGATTTTC CTGGTCACTG GCCAGGAGTG GTCGACAAGA TAGACTATTA CTTGCAATCA 
CAGAGCAGTG CAAGCTGGCT TGGCAGTTTA TTATGCCTGT ATCAACTGGT GAAGACATAT 
GAATATAAGA AAGCAGAAGA GAGAGAACCT CTTATAATAG CAATGCAGAT ATTCCTGCCT 
CGTATTCAGC AACAAATTGT TCAGCTCCTT CCTGATTCCT CCTATTATTC TGTATTACTG 
CAGAAACAAA TTCTGAAAAT CTTTTATGCA CTTGTTCAGT ATGCATTGCC TCTTCAGCTA 
GTGAATAACC AAACCATGAC AACATGGATG GAGATCTTCC GAACTATTAT CGACAGGACC 
GTTCCTCCTG AGACTCTGCA CATTGATGAG GATGATAGAC CAGAACTGGT ATGGTGGAAG 
TGTAAGAAGT GGGCACTGCA TATTGTAGCT CGGCTCTTTG AACGATATGG AAGCCCAGGA 
AATGTCACAA AAGAATACTT TGAATTTTCT GAATTCTTTT TGAAAACCTA TGCAGTGGGC 
ATTCAGCAGG TGCTACTAAA AATTTTAGAT CAATATAGAC AGAAAGAATA TGTAGCTCCC 
CGTGTTCTTC AGCAAGCATT CAACTATCTC AACCAAGGGG TGGTTCATTC TATAACCTGG 
AAGCAGATGA AGCCACACAT ACAGAATATC TCTGAAGATG TGATTTTTTC TGTGATGTGT 
TATAAAGATG AGGATGAAGA GCTGTGGCAA GAAGATCCAT ATGAGTATAT AAGGATGAAA 
TTTGATATTT TTGAAGATTA TGCTTCTCCC ACCACAGCAG CCCAGACTCT CTTATATACT 
GCTGCAAAGA AAAGAAAAGA GGTGTTGCCA AAAATGATGG CATTCTGTTA TCAAATCCTG 
ACAGACCCGA ACTTTGACCC TAGGAAGAAA GATGGAGCCC TGCATGTGAT TGGTTCCCTA 
GCTGAGATTT TACTGAAGAA GAGTTTATTC AAGGACCAAA TGGAGCTGTT TCTACAAAAT 
CATGTATTTC CATTATTATT GTCTAACCTG GGATATCTTC GAGCTAGATC TTGCTGGGTA 
CTTCATGCAT TTAGTTCTTT GAAGTTCCAT AATGAGCTCA ATCTAAGAAA TGCCGTTGAA 
TTAGCGAAGA AGAGCCTGAT TGAAGATAAA GAGATGCCTG TCAAAGTTGA AGCTGCCCTT 
GCTCTTCAGT CTTTAATTTC TAACCAGATA CAAGCTAAGG AATATATGAA GCCACATGTG 
AGGCCTATTA TGCAGGAACT GTTGCACATT GTTAGAGAGA CAGAAAATGA TGATGTTACT 
AATGTCATCC AGAAGATGAT ATGTGAATAC AGTCAAGAGG TAGCCTCAAT TGCTGTTGAT 
ATGACCCAAC ACTTGGCTGA GATATTTGGC AAAGTTCTTC AAAGTGATGA ATATGAAGAA 
GTTGAAGACA AAACAGTAAT GGCTATGGGA ATTTTACATA CCATTGATAC TATCTTAACA 
GTTGTAGAAG ATCATAAAGA GATTACCCAG CAGTTAGAGA ATATCTGTCT ACGGATCATT 
GATCTTGTTC TGCAGAAACA TGTAATTGAA TTCTATGAAG AAATTCTTTC CCTGGCATAC 
AGTTTAACCT GCCACAGTAT TTCCCCTCAA ATGTGGCAGC TTCTAGGTAT ACTATATGAA 
GTGTTTCAGC AGGATTGCTT TGAATACTTT ACAGACATGA TGCCTCTCCT GCATAATTAT 
GTGACAATAG ATACAGATAC CTTACTATCA AATGCAAAAC ATTTAGAAAT TCTTTTTACA 
ATGTGTAGGA AGGTACTATG TGGAGATGCA GGAGAAGATG CAGAGTGTCA TGCAGCTAAA 
CTTCTGGAAG TCATCATTCT TCAGTGCAAA GGAAGGGGAA TTGATCAGTG CATTCCACTC 
TTCGTTCAAC TTGTTTTGGA GAGATTAACT CGAGGGGTCA AAACTAGTGA GCTTCGTACT 
ATGTGTCTTC AGGTTGCAAT TGCTGCCTTG TACTACAACC CTGATTTGCT GCTACATACT 
TTAGAACGAA TTCAGTTGCC TCACAACCCT GGACCTATCA CTGTACAGTT TATAAATCAA 
TGGATGAATG ATACAGATTG TTTTCTTGGG CATCATGACC GGAAGATGTG TATAATAGGA 
CTGAGTATCC TTTTGGAATT GCAAAATCGA CCTCCTGCAG TAGATGCTGT GGTGGGACAG 
ATTGTTCCCT CAATTCTTTT CCTTTTCCTT GGCCTAAAGC AGGTCTGTGC TACTAGACAA 
CTGGTAAACC GGGAAGATCG TTCAAAAGCA GAGAAAGCTG ATATGGAAGA AAATGAGGAG 
ATTTCAAGTG ATGAAGAGGA GACAAATGTA ACTGCTCAAG CAATGCAGTC AAATAATGGA 
AGAGGTGAAG ATGAGGAGGA GGAAGATGAT GACTGGGATG AAGAAGTATT GGAAGAAACC 
GCGCTTGAGG GGTTCAGTAC TCCACTTGAC CTTGACAATA GTGTGGATGA ATATCAGTTT 
TTTACACAAG CTCTGATAAC TGTGCAGAGT CGAGATGCAG CCTGGTACCA GCTGCTGATG 
GCACCACTCA GCGAGGATCA GAGGACAGCA CTGCAGGAGG TGTACACACT GGCAGAGCAC 
CGACGGACGG TGGCAGAGGC AAAGAAGAAG ATTGAACAAC AGGGAGGCTT CACCTTTGAA 
AACAAAGGAG TCCTCTCCGC ATTTAATTTT GGGACTGTGC CCAGCAACAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006381.2
CDS	223..3336
Translation	MDLNRIIQALKGTIDPKLRIAAENELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRAIIKHDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLPRIQQQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRTVPPETLHIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVGIQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVIFSVMCYKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQILTDPNFDPRKKDGALHVIGSLAEILLKKSLFKDQMELFLQNHVFPLLLSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPVKVEAALALQSLISNQIQAKEYMKPHVRPIMQELLHIVRETENDDVTNVIQKMICEYSQEVASIAVDMTQHLAEIFGKVLQSDEYEEVEDKTVMAMGILHTIDTILTVVEDHKEITQQLENICLRIIDLVLQKHVIEFYEEILSLAYSLTCHSISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTIDTDTLLSNAKHLEILFTMCRKVLCGDAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLTRGVKTSELRTMCLQVAIAALYYNPDLLLHTLERIQLPHNPGPITVQFINQWMNDTDCFLGHHDRKMCIIGLSILLELQNRPPAVDAVVGQIVPSILFLFLGLKQVCATRQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETALEGFSTPLDLDNSVDEYQFFTQALITVQSRDAAWYQLLMAPLSEDQRTALQEVYTLAEHRRTVAEAKKKIEQQGGFTFENKGVLSAFNFGTVPSNN

Target ORF information:

RefSeq Version	NM_006390.4
Organism	Homo sapiens(human)
Definition	Homo sapiens importin 8 (IPO8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006390.4

ORF Insert Sequence:

ATGGACCTCA ACCGGATCAT CCAGGCGCTG AAGGGCACCA TCGACCCGAA GTTGCGGATT 
GCAGCCGAGA ACGAGCTCAA CCAGTCCTAC AAGATTATCA ATTTTGCCCC CAGTTTACTT 
CGGATTATAG TCTCTGACCA TGTGGAATTC CCAGTACGAC AGGCAGCTGC CATTTACCTG 
AAGAACATGG TGACACAATA CTGGCCAGAT CGAGAACCTC CACCAGGAGA AGCAATATTT 
CCATTCAACA TTCACGAAAA CGATCGCCAG CAAATACGTG ATAACATTGT GGAAGGAATA 
ATTCGGTCTC CAGATTTAGT GAGAGTCCAA TTAACAATGT GTCTCCGTGC CATCATAAAA 
CATGATTTTC CTGGTCACTG GCCAGGAGTG GTCGACAAGA TAGACTATTA CTTGCAATCA 
CAGAGCAGTG CAAGCTGGCT TGGCAGTTTA TTATGCCTGT ATCAACTGGT GAAGACATAT 
GAATATAAGA AAGCAGAAGA GAGAGAACCT CTTATAATAG CAATGCAGAT ATTCCTGCCT 
CGTATTCAGC AACAAATTGT TCAGCTCCTT CCTGATTCCT CCTATTATTC TGTATTACTG 
CAGAAACAAA TTCTGAAAAT CTTTTATGCA CTTGTTCAGT ATGCATTGCC TCTTCAGCTA 
GTGAATAACC AAACCATGAC AACATGGATG GAGATCTTCC GAACTATTAT CGACAGGACC 
GTTCCTCCTG AGACTCTGCA CATTGATGAG GATGATAGAC CAGAACTGGT ATGGTGGAAG 
TGTAAGAAGT GGGCACTGCA TATTGTAGCT CGGCTCTTTG AACGATATGG AAGCCCAGGA 
AATGTCACAA AAGAATACTT TGAATTTTCT GAATTCTTTT TGAAAACCTA TGCAGTGGGC 
ATTCAGCAGG TGCTACTAAA AATTTTAGAT CAATATAGAC AGAAAGAATA TGTAGCTCCC 
CGTGTTCTTC AGCAAGCATT CAACTATCTC AACCAAGGGG TGGTTCATTC TATAACCTGG 
AAGCAGATGA AGCCACACAT ACAGAATATC TCTGAAGATG TGATTTTTTC TGTGATGTGT 
TATAAAGATG AGGATGAAGA GCTGTGGCAA GAAGATCCAT ATGAGTATAT AAGGATGAAA 
TTTGATATTT TTGAAGATTA TGCTTCTCCC ACCACAGCAG CCCAGACTCT CTTATATACT 
GCTGCAAAGA AAAGAAAAGA GGTGTTGCCA AAAATGATGG CATTCTGTTA TCAAATCCTG 
ACAGACCCGA ACTTTGACCC TAGGAAGAAA GATGGAGCCC TGCATGTGAT TGGTTCCCTA 
GCTGAGATTT TACTGAAGAA GAGTTTATTC AAGGACCAAA TGGAGCTGTT TCTACAAAAT 
CATGTATTTC CATTATTATT GTCTAACCTG GGATATCTTC GAGCTAGATC TTGCTGGGTA 
CTTCATGCAT TTAGTTCTTT GAAGTTCCAT AATGAGCTCA ATCTAAGAAA TGCCGTTGAA 
TTAGCGAAGA AGAGCCTGAT TGAAGATAAA GAGATGCCTG TCAAAGTTGA AGCTGCCCTT 
GCTCTTCAGT CTTTAATTTC TAACCAGATA CAAGCTAAGG AATATATGAA GCCACATGTG 
AGGCCTATTA TGCAGGAACT GTTGCACATT GTTAGAGAGA CAGAAAATGA TGATGTTACT 
AATGTCATCC AGAAGATGAT ATGTGAATAC AGTCAAGAGG TAGCCTCAAT TGCTGTTGAT 
ATGACCCAAC ACTTGGCTGA GATATTTGGC AAAGTTCTTC AAAGTGATGA ATATGAAGAA 
GTTGAAGACA AAACAGTAAT GGCTATGGGA ATTTTACATA CCATTGATAC TATCTTAACA 
GTTGTAGAAG ATCATAAAGA GATTACCCAG CAGTTAGAGA ATATCTGTCT ACGGATCATT 
GATCTTGTTC TGCAGAAACA TGTAATTGAA TTCTATGAAG AAATTCTTTC CCTGGCATAC 
AGTTTAACCT GCCACAGTAT TTCCCCTCAA ATGTGGCAGC TTCTAGGTAT ACTATATGAA 
GTGTTTCAGC AGGATTGCTT TGAATACTTT ACAGACATGA TGCCTCTCCT GCATAATTAT 
GTGACAATAG ATACAGATAC CTTACTATCA AATGCAAAAC ATTTAGAAAT TCTTTTTACA 
ATGTGTAGGA AGGTACTATG TGGAGATGCA GGAGAAGATG CAGAGTGTCA TGCAGCTAAA 
CTTCTGGAAG TCATCATTCT TCAGTGCAAA GGAAGGGGAA TTGATCAGTG CATTCCACTC 
TTCGTTCAAC TTGTTTTGGA GAGATTAACT CGAGGGGTCA AAACTAGTGA GCTTCGTACT 
ATGTGTCTTC AGGTTGCAAT TGCTGCCTTG TACTACAACC CTGATTTGCT GCTACATACT 
TTAGAACGAA TTCAGTTGCC TCACAACCCT GGACCTATCA CTGTACAGTT TATAAATCAA 
TGGATGAATG ATACAGATTG TTTTCTTGGG CATCATGACC GGAAGATGTG TATAATAGGA 
CTGAGTATCC TTTTGGAATT GCAAAATCGA CCTCCTGCAG TAGATGCTGT GGTGGGACAG 
ATTGTTCCCT CAATTCTTTT CCTTTTCCTT GGCCTAAAGC AGGTCTGTGC TACTAGACAA 
CTGGTAAACC GGGAAGATCG TTCAAAAGCA GAGAAAGCTG ATATGGAAGA AAATGAGGAG 
ATTTCAAGTG ATGAAGAGGA GACAAATGTA ACTGCTCAAG CAATGCAGTC AAATAATGGA 
AGAGGTGAAG ATGAGGAGGA GGAAGATGAT GACTGGGATG AAGAAGTATT GGAAGAAACC 
GCGCTTGAGG GGTTCAGTAC TCCACTTGAC CTTGACAATA GTGTGGATGA ATATCAGTTT 
TTTACACAAG CTCTGATAAC TGTGCAGAGT CGAGATGCAG CCTGGTACCA GCTGCTGATG 
GCACCACTCA GCGAGGATCA GAGGACAGCA CTGCAGGAGG TGTACACACT GGCAGAGCAC 
CGACGGACGG TGGCAGAGGC AAAGAAGAAG ATTGAACAAC AGGGAGGCTT CACCTTTGAA 
AACAAAGGAG TCCTCTCCGC ATTTAATTTT GGGACTGTGC CCAGCAACAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

RUNX2 controls human IPO8 basal transcription in Saos-2 cells.
Molecular medicine reports14(2)1418-24(2016 Aug)
Xiong J,Hu Z,Wang T,Xu X,Liu J,Wu P,Che X,Li W

Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E.
Proceedings of the National Academy of Sciences of the United States of America113(19)5263-8(2016 May)
Volpon L,Culjkovic-Kraljacic B,Osborne MJ,Ramteke A,Sun Q,Niesman A,Chook YM,Borden KL

Functional characterization of importin ?8 as a classical nuclear localization signal receptor.
Biochimica et biophysica acta1853(10 Pt A)2676-83(2015 Oct)
Kimoto C,Moriyama T,Tsujii A,Igarashi Y,Obuse C,Miyamoto Y,Oka M,Yoneda Y

Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism.
Nature524(7565)361-5(2015 Aug)
Perera RM,Stoykova S,Nicolay BN,Ross KN,Fitamant J,Boukhali M,Lengrand J,Deshpande V,Selig MK,Ferrone CR,Settleman J,Stephanopoulos G,Dyson NJ,Zoncu R,Ramaswamy S,Haas W,Bardeesy N

KPNB1, XPO7 and IPO8 mediate the translocation ofNF-?B/p65 into the nucleus.
Traffic (Copenhagen, Denmark)14(11)1132-43(2013 Nov)
Liang P,Zhang H,Wang G,Li S,Cong S,Luo Y,Zhang B

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IPO8 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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