Gene Symbol | MERTK |
Entrez Gene ID | 10461 |
Full Name | MER proto-oncogene, tyrosine kinase |
Synonyms | MER,RP38,Tyro12,c-Eyk,c-mer |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Retinitis pigmentosa 38, 613862 (3) |