JMJD7 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	JMJD7
Entrez Gene ID	100137047
Full Name	jumonji domain containing 7
General protein information	Preferred Names jumonji domain containing 7 Names jmjC domain-containing protein 7 jumonji domain-containing protein 7
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q15.1
Summary	This gene encodes a highly conserved protein with a JmjC domain, which are part of the cupin metalloenzyme superfamily. JmjC proteins may function as 2-oxoglutarate-Fe(II)-dependent dioxygenases. Most tissues also express read-through transcripts from this gene into the downstream phospholipase A2, group IVB (cytosolic) gene, some of which may encode fusion proteins combining the N-terminus of this protein with the phospholipase A2, group IVB protein. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001114632.1	NP_001108104.1	jmjC domain-containing protein 7
NM_001114632.2	NP_001108104.1	bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	JMJD7	XP_001150828.1
Mus musculus (house mouse)	Jmjd7	NP_001108109.1
Rattus norvegicus (Norway rat)	Jmjd7	NP_001108128.1
Canis lupus familiaris (dog)	JMJD7	NP_001191164.1
Magnaporthe oryzae (rice blast fungus)	MGG_08136	XP_003715099.1
Xenopus tropicalis (tropical clawed frog)	jmjd7	NP_001011279.1
Bos taurus (cattle)	JMJD7	NP_001108130.1
Drosophila melanogaster (fruit fly)	CG10133	NP_648651.1
Neurospora crassa	NCU03670	XP_961446.2
Oryza sativa (rice)	Os09g0483600	NP_001063511.1
Homo sapiens (human)	JMJD7	NP_001108104.1
Gallus gallus (chicken)	JMJD7	NP_001108131.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007766	XP_317749.4
Danio rerio (zebrafish)	jmjd7	NP_001017615.1
Arabidopsis thaliana (thale cress)	AT3G45880	NP_190174.2

Gene Ontology
Bibliography

Related articles in PubMed

Clipping of arginine-methylated histone tails by JMJD5 and JMJD7.
Liu H, Wang C, Lee S, Deng Y, Wither M, Oh S, Ning F, Dege C, Zhang Q, Liu X, Johnson AM, Zang J, Chen Z, Janknecht R, Hansen K, Marrack P, Li CY, Kappler JW, Hagman J, Zhang G
Proceedings of the National Academy of Sciences of the United States of America114(37)E7717-E7726(2017 Sep)

A novel read-through transcript JMJD7-PLA2G4B regulates head and neck squamous cell carcinoma cell proliferation and survival.
Cheng Y, Wang Y, Li J, Chang I, Wang CY
Oncotarget8(2)1972-1982(2017 Jan)

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S,
Diabetes care33(10)2250-3(2010 Oct)

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, , ,
American journal of human genetics85(5)628-42(2009 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

The following JMJD7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the JMJD7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30588	NM_001114632.2 Latest version!	Homo sapiens jumonji domain containing 7 (JMJD7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
View Old Accession Versions >>
OHu30588	NM_001114632.1	Homo sapiens jumonji domain containing 7 (JMJD7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

JMJD7 ( NM_001114632.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001108104.1 Homo sapiens jumonji domain containing 7 (JMJD7), mRNA.

Price & Availability↑

CloneID	OHu30588
Clone ID Related Accession (Same CDS sequence)	NM_001114632.1 , NM_001114632.2
Accession Version	NM_001114632.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 951bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	jmjC domain-containing protein 7
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK289833.1, DA100207.1, BC139899.1 and BU739980.1. On or before Aug 17, 2008 this sequence version replaced XM_001723659.1, XM_001725545.1, XM_001720570.1. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.258917.1, SRR1163658.317015.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGAGG CGGCTTTGGA AGCCGTGCGG AGCGAGTTAC GAGAATTCCC GGCCGCTGCA 
AGGGAGCTCT GCGTGCCTCT TGCTGTGCCC TACCTGGACA AACCCCCAAC TCCGCTCCAC 
TTCTACCGGG ACTGGGTCTG CCCCAACAGG CCGTGCATTA TCCGCAACGC TCTGCAGCAC 
TGGCCGGCCC TCCAGAAGTG GTCCCTCCCC TATTTCAGAG CCACAGTGGG CTCCACAGAG 
GTGAGTGTGG CCGTGACCCC AGATGGTTAC GCGGATGCCG TGAGAGGGGA TCGCTTCATG 
ATGCCAGCTG AGCGCCGCCT GCCCCTGAGC TTCGTGCTGG ATGTGCTGGA GGGCCGGGCC 
CAGCACCCTG GAGTCCTCTA TGTGCAGAAG CAGTGCTCCA ACCTGCCCAG CGAGCTGCCC 
CAGCTGCTGC CTGATCTGGA ATCCCATGTG CCCTGGGCCT CCGAAGCCCT GGGAAAGATG 
CCCGATGCTG TGAACTTCTG GCTGGGGGAG GCGGCTGCAG TGACTTCTTT GCACAAGGAC 
CACTATGAGA ACCTCTACTG CGTGGTCTCA GGAGAGAAGC ATTTCCTGTT CCATCCGCCC 
AGCGACCGGC CCTTCATCCC CTATGAGCTG TACACGCCGG CAACCTACCA GCTAACTGAA 
GAGGGCACCT TTAAGGTGGT GGATGAAGAG GCCATGGAGA AGGTGCCCTG GATCCCACTG 
GACCCCTTGG CGCCAGACCT AGCACGGTAC CCTAGTTACA GTCAGGCCCA GGCCCTTCGC 
TGCACGGTGC GGGCCGGTGA GATGCTCTAT CTGCCGGCTC TGTGGTTCCA CCACGTCCAG 
CAGTCCCAGG GCTGCATCGC AGTGAATTTC TGGTATGACA TGGAATACGA CCTCAAGTAT 
AGTTACTTCC AGCTGCTCGA CTCCCTCACC AAGGCTTCAG GCCTTGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001108104.1
CDS	41..991
Translation	MAEAALEAVRSELREFPAAARELCVPLAVPYLDKPPTPLHFYRDWVCPNRPCIIRNALQHWPALQKWSLPYFRATVGSTEVSVAVTPDGYADAVRGDRFMMPAERRLPLSFVLDVLEGRAQHPGVLYVQKQCSNLPSELPQLLPDLESHVPWASEALGKMPDAVNFWLGEAAAVTSLHKDHYENLYCVVSGEKHFLFHPPSDRPFIPYELYTPATYQLTEEGTFKVVDEEAMEKVPWIPLDPLAPDLARYPSYSQAQALRCTVRAGEMLYLPALWFHHVQQSQGCIAVNFWYDMEYDLKYSYFQLLDSLTKASGLD

Target ORF information:

RefSeq Version	NM_001114632.1
Organism	Homo sapiens(human)
Definition	Homo sapiens jumonji domain containing 7 (JMJD7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001114632.1

ORF Insert Sequence:

ATGGCGGAGG CGGCTTTGGA AGCCGTGCGG AGCGAGTTAC GAGAATTCCC GGCCGCTGCA 
AGGGAGCTCT GCGTGCCTCT TGCTGTGCCC TACCTGGACA AACCCCCAAC TCCGCTCCAC 
TTCTACCGGG ACTGGGTCTG CCCCAACAGG CCGTGCATTA TCCGCAACGC TCTGCAGCAC 
TGGCCGGCCC TCCAGAAGTG GTCCCTCCCC TATTTCAGAG CCACAGTGGG CTCCACAGAG 
GTGAGTGTGG CCGTGACCCC AGATGGTTAC GCGGATGCCG TGAGAGGGGA TCGCTTCATG 
ATGCCAGCTG AGCGCCGCCT GCCCCTGAGC TTCGTGCTGG ATGTGCTGGA GGGCCGGGCC 
CAGCACCCTG GAGTCCTCTA TGTGCAGAAG CAGTGCTCCA ACCTGCCCAG CGAGCTGCCC 
CAGCTGCTGC CTGATCTGGA ATCCCATGTG CCCTGGGCCT CCGAAGCCCT GGGAAAGATG 
CCCGATGCTG TGAACTTCTG GCTGGGGGAG GCGGCTGCAG TGACTTCTTT GCACAAGGAC 
CACTATGAGA ACCTCTACTG CGTGGTCTCA GGAGAGAAGC ATTTCCTGTT CCATCCGCCC 
AGCGACCGGC CCTTCATCCC CTATGAGCTG TACACGCCGG CAACCTACCA GCTAACTGAA 
GAGGGCACCT TTAAGGTGGT GGATGAAGAG GCCATGGAGA AGGTGCCCTG GATCCCACTG 
GACCCCTTGG CGCCAGACCT AGCACGGTAC CCTAGTTACA GTCAGGCCCA GGCCCTTCGC 
TGCACGGTGC GGGCCGGTGA GATGCTCTAT CTGCCGGCTC TGTGGTTCCA CCACGTCCAG 
CAGTCCCAGG GCTGCATCGC AGTGAATTTC TGGTATGACA TGGAATACGA CCTCAAGTAT 
AGTTACTTCC AGCTGCTCGA CTCCCTCACC AAGGCTTCAG GCCTTGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JMJD7 ( NM_001114632.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001108104.1 Homo sapiens jumonji domain containing 7 (JMJD7), mRNA.

Price & Availability↑

CloneID	OHu30588
Clone ID Related Accession (Same CDS sequence)	NM_001114632.1 , NM_001114632.2
Accession Version	NM_001114632.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 951bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-18
Organism	Homo sapiens(human)
Product	bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK289833.1, DA100207.1 and BC139899.1. On Nov 23, 2018 this sequence version replaced NM_001114632.1. ##Evidence-Data-START## Transcript exon combination :: SRR5189655.114844.1, SRR1163658.317015.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000397299.9/ ENSP00000380467.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGAGG CGGCTTTGGA AGCCGTGCGG AGCGAGTTAC GAGAATTCCC GGCCGCTGCA 
AGGGAGCTCT GCGTGCCTCT TGCTGTGCCC TACCTGGACA AACCCCCAAC TCCGCTCCAC 
TTCTACCGGG ACTGGGTCTG CCCCAACAGG CCGTGCATTA TCCGCAACGC TCTGCAGCAC 
TGGCCGGCCC TCCAGAAGTG GTCCCTCCCC TATTTCAGAG CCACAGTGGG CTCCACAGAG 
GTGAGTGTGG CCGTGACCCC AGATGGTTAC GCGGATGCCG TGAGAGGGGA TCGCTTCATG 
ATGCCAGCTG AGCGCCGCCT GCCCCTGAGC TTCGTGCTGG ATGTGCTGGA GGGCCGGGCC 
CAGCACCCTG GAGTCCTCTA TGTGCAGAAG CAGTGCTCCA ACCTGCCCAG CGAGCTGCCC 
CAGCTGCTGC CTGATCTGGA ATCCCATGTG CCCTGGGCCT CCGAAGCCCT GGGAAAGATG 
CCCGATGCTG TGAACTTCTG GCTGGGGGAG GCGGCTGCAG TGACTTCTTT GCACAAGGAC 
CACTATGAGA ACCTCTACTG CGTGGTCTCA GGAGAGAAGC ATTTCCTGTT CCATCCGCCC 
AGCGACCGGC CCTTCATCCC CTATGAGCTG TACACGCCGG CAACCTACCA GCTAACTGAA 
GAGGGCACCT TTAAGGTGGT GGATGAAGAG GCCATGGAGA AGGTGCCCTG GATCCCACTG 
GACCCCTTGG CGCCAGACCT AGCACGGTAC CCTAGTTACA GTCAGGCCCA GGCCCTTCGC 
TGCACGGTGC GGGCCGGTGA GATGCTCTAT CTGCCGGCTC TGTGGTTCCA CCACGTCCAG 
CAGTCCCAGG GCTGCATCGC AGTGAATTTC TGGTATGACA TGGAATACGA CCTCAAGTAT 
AGTTACTTCC AGCTGCTCGA CTCCCTCACC AAGGCTTCAG GCCTTGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001108104.1
CDS	34..984
Translation	MAEAALEAVRSELREFPAAARELCVPLAVPYLDKPPTPLHFYRDWVCPNRPCIIRNALQHWPALQKWSLPYFRATVGSTEVSVAVTPDGYADAVRGDRFMMPAERRLPLSFVLDVLEGRAQHPGVLYVQKQCSNLPSELPQLLPDLESHVPWASEALGKMPDAVNFWLGEAAAVTSLHKDHYENLYCVVSGEKHFLFHPPSDRPFIPYELYTPATYQLTEEGTFKVVDEEAMEKVPWIPLDPLAPDLARYPSYSQAQALRCTVRAGEMLYLPALWFHHVQQSQGCIAVNFWYDMEYDLKYSYFQLLDSLTKASGLD

Target ORF information:

RefSeq Version	NM_001114632.2
Organism	Homo sapiens(human)
Definition	Homo sapiens jumonji domain containing 7 (JMJD7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001114632.2

ORF Insert Sequence:

ATGGCGGAGG CGGCTTTGGA AGCCGTGCGG AGCGAGTTAC GAGAATTCCC GGCCGCTGCA 
AGGGAGCTCT GCGTGCCTCT TGCTGTGCCC TACCTGGACA AACCCCCAAC TCCGCTCCAC 
TTCTACCGGG ACTGGGTCTG CCCCAACAGG CCGTGCATTA TCCGCAACGC TCTGCAGCAC 
TGGCCGGCCC TCCAGAAGTG GTCCCTCCCC TATTTCAGAG CCACAGTGGG CTCCACAGAG 
GTGAGTGTGG CCGTGACCCC AGATGGTTAC GCGGATGCCG TGAGAGGGGA TCGCTTCATG 
ATGCCAGCTG AGCGCCGCCT GCCCCTGAGC TTCGTGCTGG ATGTGCTGGA GGGCCGGGCC 
CAGCACCCTG GAGTCCTCTA TGTGCAGAAG CAGTGCTCCA ACCTGCCCAG CGAGCTGCCC 
CAGCTGCTGC CTGATCTGGA ATCCCATGTG CCCTGGGCCT CCGAAGCCCT GGGAAAGATG 
CCCGATGCTG TGAACTTCTG GCTGGGGGAG GCGGCTGCAG TGACTTCTTT GCACAAGGAC 
CACTATGAGA ACCTCTACTG CGTGGTCTCA GGAGAGAAGC ATTTCCTGTT CCATCCGCCC 
AGCGACCGGC CCTTCATCCC CTATGAGCTG TACACGCCGG CAACCTACCA GCTAACTGAA 
GAGGGCACCT TTAAGGTGGT GGATGAAGAG GCCATGGAGA AGGTGCCCTG GATCCCACTG 
GACCCCTTGG CGCCAGACCT AGCACGGTAC CCTAGTTACA GTCAGGCCCA GGCCCTTCGC 
TGCACGGTGC GGGCCGGTGA GATGCTCTAT CTGCCGGCTC TGTGGTTCCA CCACGTCCAG 
CAGTCCCAGG GCTGCATCGC AGTGAATTTC TGGTATGACA TGGAATACGA CCTCAAGTAT 
AGTTACTTCC AGCTGCTCGA CTCCCTCACC AAGGCTTCAG GCCTTGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Clipping of arginine-methylated histone tails by JMJD5 and JMJD7.
Proceedings of the National Academy of Sciences of the United States of America114(37)E7717-E7726(2017 Sep)
Liu H,Wang C,Lee S,Deng Y,Wither M,Oh S,Ning F,Dege C,Zhang Q,Liu X,Johnson AM,Zang J,Chen Z,Janknecht R,Hansen K,Marrack P,Li CY,Kappler JW,Hagman J,Zhang G

A novel read-through transcript JMJD7-PLA2G4B regulates head and neck squamous cell carcinoma cell proliferation and survival.
Oncotarget8(2)1972-1982(2017 Jan)
Cheng Y,Wang Y,Li J,Chang I,Wang CY

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Diabetes care33(10)2250-3(2010 Oct)
Bailey SD,Xie C,Do R,Montpetit A,Diaz R,Mohan V,Keavney B,Yusuf S,Gerstein HC,Engert JC,Anand S,

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
American journal of human genetics85(5)628-42(2009 Nov)
Talmud PJ,Drenos F,Shah S,Shah T,Palmen J,Verzilli C,Gaunt TR,Pallas J,Lovering R,Li K,Casas JP,Sofat R,Kumari M,Rodriguez S,Johnson T,Newhouse SJ,Dominiczak A,Samani NJ,Caulfield M,Sever P,Stanton A,Shields DC,Padmanabhan S,Melander O,Hastie C,Delles C,Ebrahim S,Marmot MG,Smith GD,Lawlor DA,Munroe PB,Day IN,Kivimaki M,Whittaker J,Humphries SE,Hingorani AD,,,

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JMJD7 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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