GAP43 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	GAP43
Entrez Gene ID	427955
Full Name	growth associated protein 43
Synonyms	GAP-43
General protein information	Preferred Names growth associated protein 43 Names neuromodulin axonal membrane protein GAP-43
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001305054.1	NP_001291983.1	neuromodulin

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Gap43	NP_032109.1
Xenopus tropicalis (tropical clawed frog)	gap43	NP_001072212.1
Canis lupus familiaris (dog)	GAP43	XP_535747.1
Pan troglodytes (chimpanzee)	GAP43	NP_001009816.1
Bos taurus (cattle)	GAP43	NP_976234.2
Gallus gallus (chicken)	GAP43	XP_425527.3
	GAP43	XP_001107759.2
Homo sapiens (human)	GAP43	NP_001123536.1
Rattus norvegicus (Norway rat)	Gap43	NP_058891.1

Gene Ontology
Bibliography

Related articles in PubMed

Differential expression of GAP-43 protein in the rostral brain neurons of early chick embryos.
Onodera N, Kakehata A, Araki I
The Tohoku journal of experimental medicine231(4)293-8(2013 12)

Overexpression of GAP-43 reveals unexpected properties of hippocampal mossy fibers.
Rekart JL, Routtenberg A
Hippocampus20(1)46-57(2010 Jan)

Ectopic growth of hippocampal mossy fibers in a mutated GAP-43 transgenic mouse with impaired spatial memory retention.
Holahan MR, Honegger KS, Routtenberg A
Hippocampus20(1)58-64(2010 Jan)

Conservation and expression of IQ-domain-containing calpacitin gene products (neuromodulin/GAP-43, neurogranin/RC3) in the adult and developing oscine song control system.
Clayton DF, George JM, Mello CV, Siepka SM
Developmental neurobiology69(2-3)124-40(2009 Feb 1-15)

GAP-43 gene expression regulates information storage.
Holahan MR, Honegger KS, Tabatadze N, Routtenberg A
Learning & memory (Cold Spring Harbor, N.Y.)14(6)407-15(2007 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

GAP-43 protein is expressed in the rostral brain neurons of early chick embryos
Title: Differential expression of GAP-43 protein in the rostral brain neurons of early chick embryos.

first evidence that links increased GAP-43 expression with growth of central axons; findings raise questions about the properties of granule cells and the mossy fiber mechanisms that differentially regulate axonal remodeling in the adult hippocampus
Title: Overexpression of GAP-43 reveals unexpected properties of hippocampal mossy fibers.

permanently dephosphorylated GAP-43 may disrupt normal axonal fasciculation which gives rise to the ectopic growth into distal stratum oriens
Title: Ectopic growth of hippocampal mossy fibers in a mutated GAP-43 transgenic mouse with impaired spatial memory retention.

GAP-43 expression in the adult and developing oscine song control system.
Title: Conservation and expression of IQ-domain-containing calpacitin gene products (neuromodulin/GAP-43, neurogranin/RC3) in the adult and developing oscine song control system.

role of GAP-43 protein levels in regulating memory function
Title: GAP-43 gene expression regulates information storage.

The following GAP43 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GAP43 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa02418	NM_001305054.1 Latest version!	Gallus gallus growth associated protein 43 (GAP43), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GAP43 ( NM_001305054.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001291983.1 Gallus gallus growth associated protein 43 (GAP43), mRNA.

Price & Availability↑

CloneID	OGa02418
Clone ID Related Accession (Same CDS sequence)	NM_001305054.1
Accession Version	NM_001305054.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 741bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Gallus gallus(chicken)
Product	neuromodulin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AADN05000813.1 and CN210811.1. On Feb 20, 2015 this sequence version replaced XM_425527.4. ##Evidence-Data-START## Transcript exon combination :: ERR2368565.64374.1, ERR2368565.103039.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2201363, SAMEA2201366 [ECO:0000348] ##Evidence-Data-END##

ATGCTGTGCT GTATGAGAAG AACAAAACAG GTTGAAAAAA ATGAGGACGG GGACCAAAAG 
ATTGAGCAAG ATGGCATCAA ACCAGAAGAT AAAGCTCATA AGGCAGCCAC CAAAATCCAG 
GCCAGCTTCC GTGGACACAT AACAAGGAAA AAGCTCAAGG GAGAGAAGAA GGCAGATGCC 
CCCGCATCCG AGTCTGAGGC CGCCGACAAG AAGGACGAAG GCCCTGCTGG CGGAGCGGCC 
GAGAACAAAG AGAGTGAGGC TTCCGCTGCC ACAGAGGCCA GCGCCGCCGA CAGTGCCCAG 
CTGGACGAGG GCAGCAAAGA CAGCAGCGTG CCAGCAGAGG AGAAAAAAGG GAATGGAGCC 
GCTGACACGG GCTCAGAGCA GCCAGCCCCG CAGGCTGCCA CTCCTGCTGC CTCCTCGGAG 
GAAAAACCCG CTGCCGCCGC CGAGACGGAA AGTGCCACTA AAGCTTCCAC TGATAACTCG 
CCATCCTTGA AGGCTGACGA AGCCCAAGAC AAAGAGGAGC CTAAACAAGC CGACGTGCCT 
GCTGCTGACA CCACTGCCAC CACCACCCCT GCCGCAGAGG ATGCTACTGC CAAGGCAACA 
GCGCAACCCC AAATGGAGAC AGTGGAGAGC AGCCAAACCG AAGAGAAGAC AGATGCTGTA 
GAAGAAACCA AACCTACTGA AAGTGCCCAG CAGGAAGAGG TGAAAGAAGA AGAGAGCAAG 
GCGGACCAAG AAAATGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001291983.1
CDS	78..818
Translation	MLCCMRRTKQVEKNEDGDQKIEQDGIKPEDKAHKAATKIQASFRGHITRKKLKGEKKADAPASESEAADKKDEGPAGGAAENKESEASAATEASAADSAQLDEGSKDSSVPAEEKKGNGAADTGSEQPAPQAATPAASSEEKPAAAAETESATKASTDNSPSLKADEAQDKEEPKQADVPAADTTATTTPAAEDATAKATAQPQMETVESSQTEEKTDAVEETKPTESAQQEEVKEEESKADQENA

Target ORF information:

RefSeq Version	NM_001305054.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus growth associated protein 43 (GAP43), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001305054.1

ORF Insert Sequence:

ATGCTGTGCT GTATGAGAAG AACAAAACAG GTTGAAAAAA ATGAGGACGG GGACCAAAAG 
ATTGAGCAAG ATGGCATCAA ACCAGAAGAT AAAGCTCATA AGGCAGCCAC CAAAATCCAG 
GCCAGCTTCC GTGGACACAT AACAAGGAAA AAGCTCAAGG GAGAGAAGAA GGCAGATGCC 
CCCGCATCCG AGTCTGAGGC CGCCGACAAG AAGGACGAAG GCCCTGCTGG CGGAGCGGCC 
GAGAACAAAG AGAGTGAGGC TTCCGCTGCC ACAGAGGCCA GCGCCGCCGA CAGTGCCCAG 
CTGGACGAGG GCAGCAAAGA CAGCAGCGTG CCAGCAGAGG AGAAAAAAGG GAATGGAGCC 
GCTGACACGG GCTCAGAGCA GCCAGCCCCG CAGGCTGCCA CTCCTGCTGC CTCCTCGGAG 
GAAAAACCCG CTGCCGCCGC CGAGACGGAA AGTGCCACTA AAGCTTCCAC TGATAACTCG 
CCATCCTTGA AGGCTGACGA AGCCCAAGAC AAAGAGGAGC CTAAACAAGC CGACGTGCCT 
GCTGCTGACA CCACTGCCAC CACCACCCCT GCCGCAGAGG ATGCTACTGC CAAGGCAACA 
GCGCAACCCC AAATGGAGAC AGTGGAGAGC AGCCAAACCG AAGAGAAGAC AGATGCTGTA 
GAAGAAACCA AACCTACTGA AAGTGCCCAG CAGGAAGAGG TGAAAGAAGA AGAGAGCAAG 
GCGGACCAAG AAAATGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Differential expression of GAP-43 protein in the rostral brain neurons of early chick embryos.
The Tohoku journal of experimental medicine231(4)293-8(2013 12)
Onodera N,Kakehata A,Araki I

Overexpression of GAP-43 reveals unexpected properties of hippocampal mossy fibers.
Hippocampus20(1)46-57(2010 Jan)
Rekart JL,Routtenberg A

Ectopic growth of hippocampal mossy fibers in a mutated GAP-43 transgenic mouse with impaired spatial memory retention.
Hippocampus20(1)58-64(2010 Jan)
Holahan MR,Honegger KS,Routtenberg A

Conservation and expression of IQ-domain-containing calpacitin gene products (neuromodulin/GAP-43, neurogranin/RC3) in the adult and developing oscine song control system.
Developmental neurobiology69(2-3)124-40(2009 Feb 1-15)
Clayton DF,George JM,Mello CV,Siepka SM

GAP-43 gene expression regulates information storage.
Learning & memory (Cold Spring Harbor, N.Y.)14(6)407-15(2007 Jun)
Holahan MR,Honegger KS,Tabatadze N,Routtenberg A

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GAP43 cDNA ORF clone, Gallus gallus(chicken)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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