Gene Symbol | RORA |
Entrez Gene ID | 415377 |
Full Name | RAR related orphan receptor A |
Synonyms | RORalpha1 |
General protein information |
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Gene Type | protein-coding |
Organism | Gallus gallus(chicken) |
Summary | The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. [provided by RefSeq, Feb 2014]. |