GHR cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	GHR
Entrez Gene ID	408184
Full Name	growth hormone receptor
Synonyms	GHBP
General protein information	Preferred Names growth hormone receptor Names growth hormone receptor GH receptor growth hormone binding protein somatotropin receptor
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001001293.1	NP_001001293.1	growth hormone receptor precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	GHR	NP_788781.1
Mus musculus (house mouse)	Ghr	NP_001273299.1
Gallus gallus (chicken)	GHR	NP_001001293.1
Danio rerio (zebrafish)	ghra	NP_001077047.1
Homo sapiens (human)	GHR	NP_001229328.1
	GHR	NP_001036132.1
Rattus norvegicus (Norway rat)	Ghr	NP_058790.1
Pan troglodytes (chimpanzee)	GHR	XP_003950612.1
Canis lupus familiaris (dog)	GHR	NP_001003123.1
Xenopus tropicalis (tropical clawed frog)	ghr	XP_002933093.2

Gene Ontology
Bibliography

Related articles in PubMed

Pattern of GHR mRNA expression and body growth in the S2 line of sex-linked dwarf chickens.
Huang HY, Zhao ZH, Li SF, Liang Z, Li CM, Wang QB
Genetics and molecular research : GMR15(4)(2016 Nov)

Expression and localization of growth hormone receptor in the oviduct of the laying hen (Gallus domesticus).
Hrabia A, Grzegorzewska AK, Sechman A
Folia biologica61(3-4)271-6(2013)

Expression of genes for interleukins, neuropeptides, growth hormone receptor, and leptin receptor in adipose tissue from growing broiler chickens.
Hausman GJ, Barb CR, Fairchild BD, Gamble J, Lee-Rutherford L
Domestic animal endocrinology43(3)260-3(2012 Oct)

Let-7b regulates the expression of the growth hormone receptor gene in deletion-type dwarf chickens.
Lin S, Li H, Mu H, Luo W, Li Y, Jia X, Wang S, Jia X, Nie Q, Li Y, Zhang X
BMC genomics13306(2012 Jul)

Expression profiles of somatotropic axis genes in lines of chickens divergently selected for 56-day body weight.
Wu G, Siegel PB, Gilbert ER, Yang N, Wong EA
Animal biotechnology22(2)100-10(2011 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the molecular mechanisms underlying growth hormone receptor (GHR) in Sex-linked dwarf chickens, was examined.
Title: Pattern of GHR mRNA expression and body growth in the S2 line of sex-linked dwarf chickens.

GHR mRNA was expressed in all examined oviductal segments with a significantly lower level in the infundibulum in comparison to other parts of the oviduct; specific GHR immunoreactivity was also detected in the wall of the oviduct.
Title: Expression and localization of growth hormone receptor in the oviduct of the laying hen (Gallus domesticus).

Between 3 and 6 wk of age, growth hormone receptor expression increased with age in adipose tissue.
Title: Expression of genes for interleukins, neuropeptides, growth hormone receptor, and leptin receptor in adipose tissue from growing broiler chickens.

There is a critical miRNA, let-7b, involved in the regulation of GHR.
Title: Let-7b regulates the expression of the growth hormone receptor gene in deletion-type dwarf chickens.

Pectoralis major muscle GHR mRNA was greater in line of low weight than high weight selected chicken.
Title: Expression profiles of somatotropic axis genes in lines of chickens divergently selected for 56-day body weight.

The following GHR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GHR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa26863	NM_001001293.1 Latest version!	Gallus gallus growth hormone receptor (GHR), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GHR ( NM_001001293.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001001293.1 Gallus gallus growth hormone receptor (GHR), mRNA.

Price & Availability↑

CloneID	OGa26863
Clone ID Related Accession (Same CDS sequence)	NM_001001293.1
Accession Version	NM_001001293.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1827bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Gallus gallus(chicken)
Product	growth hormone receptor precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M74057.1. On Aug 30, 2004 this sequence version replaced XM_424779.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M74057.1 [ECO:0000332] ##Evidence-Data-END##

ATGGATCTTC GGCATCTGCT GTTTACTTTG GCACTGGTGT GTGCAAATGA CTCACTTTCT 
GCAAGTGATG ATCTTCTGCA GTGGCCACAA ATCAGCAAGT GCAGGTCACC TGAGCTGGAG 
ACATTTTCGT GTTATTGGAC TGATGGAAAG GTCACTACTT CAGGAACAAT ACAACTGTTG 
TATATGAAAA GGAGTGATGA AGACTGGAAA GAATGTCCGG ATTATATCAC TGCAGGAGAA 
AATAGCTGTT ACTTCAACAC ATCCTACACC TCGATTTGGA TACCATATTG TGTTAAGCTT 
GCCAATAAAG ATGAAGTATT TGACGAAAAG TGTTTCAGTG TTGATGAAAT AGTACTACCT 
GATCCCCCTG TGCACCTTAA CTGGACTCTG CTAAATACTA GTCAAACTGG GATCCATGGG 
GATATTCAAG TACGATGGGA TCCACCACCA ACAGCAGATG TTCAGAAAGG ATGGATTACT 
CTGGAGTATG AATTGCAGTA CAAAGAAGTT AATGAGACAA AATGGAAGGA GTTAGAACCC 
AGGCTCTCAA CAGTGGTTCC ACTGTATTCT CTGAAGATGG GAAGAGATTA TGAGATCCGA 
GTCCGATCAA GACAACGTAC CTCCGAAAAG TTTGGGGAGT TCAGTGAAAT CCTCTATGTT 
TCCTTTACTC AAGCAGGCAT TGAATTTGTT CATTGTGCTG AAGAAATCGA GTTTCCCTGG 
TTCTTAGTTG TTGTCTTCGG AGTGTGTGGG CTGGCCGTAA CAGCGATCTT AATCCTGTTG 
TCTAAACAGC CAAGGTTAAA AATGCTGATT TTTCCTCCTG TGCCAGTTCC AAAGATTAAA 
GGGATTGACC CAGATCTCTT AAAGAAAGGA AAGCTAGATG AAGTGAACTC CATCTTAGCC 
AGCCATGACA ACTACAAGAC ACAGCTATAC AATGATGACT TGTGGGTTGA GTTTATTGAA 
TTGGACATAG ATGACTCCGA TGAAAAGAAC AGAGTCTCAG ATACTGACAG GCTCCTGAGT 
GACGATCATC TGAAGTCACA CAGTTGCTTG GGAGCCAAGG ATGATGATTC TGGACGTGCC 
AGTTGTTATG AACCAGATAT TCCAGAGACA GACTTCAGTG CAAGCGACAC ATGTGATGCC 
ATCTCTGATA TTGATCAGTT CAAGAAGGTA ACTGAAAAAG AAGAGGATCT CTTGTGCCTT 
CATAGGAAAG ATGATGTTGA GGCACTTCAA AGTCTTGCCA ACACAGATAC CCAACAGCCG 
CATACTAGTA CTCAGTCTGA AAGCAGAGAG TCATGGCCAC CTTTTGCAGA CAGCACTGAC 
TCAGCTAATC CATCAGTCCA AACTCAGCTA AGTAACCAGA ATTCCCTGAC AAACACTGAC 
TTCTATGCTC AAGTGAGTGA TATTACTCCT GCTGGAAGTG TTGTACTTTC TCCAGGGCAG 
AAATCCAAGG TGGGAAGAGC ACAGTGTGAA AGCTGCACAG AACAAAACTT CACCATGGAC 
AATGCCTATT TCTGTGAGGC AGATGTGAAA AAATGTATTG CTGTGATTTC ACAGGAAGAG 
GATGAGCCGC GTGTTCAGGA GCAAAGCTGT AACGAGGACA CTTACTTCAC CACAGAAAGC 
CTTACCACTA CCGGTATCAA TCTTGGAGCT TCAATGGCAG AAACCCCAAG TATGGAAATG 
CCTGTCCCAG ACTACACTTC TATTCATATT GTTCACTCTC CACAAGGCCT TGTGCTCAAT 
GCAACTGCAC TGCCTGTGCC AGAGAAAGAA TTTAACATGT CTTGTGGCTA TGTGAGCACA 
GACCAGCTGA ACAAAATCAT GCCGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001001293.1
CDS	36..1862
Translation	MDLRHLLFTLALVCANDSLSASDDLLQWPQISKCRSPELETFSCYWTDGKVTTSGTIQLLYMKRSDEDWKECPDYITAGENSCYFNTSYTSIWIPYCVKLANKDEVFDEKCFSVDEIVLPDPPVHLNWTLLNTSQTGIHGDIQVRWDPPPTADVQKGWITLEYELQYKEVNETKWKELEPRLSTVVPLYSLKMGRDYEIRVRSRQRTSEKFGEFSEILYVSFTQAGIEFVHCAEEIEFPWFLVVVFGVCGLAVTAILILLSKQPRLKMLIFPPVPVPKIKGIDPDLLKKGKLDEVNSILASHDNYKTQLYNDDLWVEFIELDIDDSDEKNRVSDTDRLLSDDHLKSHSCLGAKDDDSGRASCYEPDIPETDFSASDTCDAISDIDQFKKVTEKEEDLLCLHRKDDVEALQSLANTDTQQPHTSTQSESRESWPPFADSTDSANPSVQTQLSNQNSLTNTDFYAQVSDITPAGSVVLSPGQKSKVGRAQCESCTEQNFTMDNAYFCEADVKKCIAVISQEEDEPRVQEQSCNEDTYFTTESLTTTGINLGASMAETPSMEMPVPDYTSIHIVHSPQGLVLNATALPVPEKEFNMSCGYVSTDQLNKIMP

Target ORF information:

RefSeq Version	NM_001001293.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus growth hormone receptor (GHR), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001001293.1

ORF Insert Sequence:

ATGGATCTTC GGCATCTGCT GTTTACTTTG GCACTGGTGT GTGCAAATGA CTCACTTTCT 
GCAAGTGATG ATCTTCTGCA GTGGCCACAA ATCAGCAAGT GCAGGTCACC TGAGCTGGAG 
ACATTTTCGT GTTATTGGAC TGATGGAAAG GTCACTACTT CAGGAACAAT ACAACTGTTG 
TATATGAAAA GGAGTGATGA AGACTGGAAA GAATGTCCGG ATTATATCAC TGCAGGAGAA 
AATAGCTGTT ACTTCAACAC ATCCTACACC TCGATTTGGA TACCATATTG TGTTAAGCTT 
GCCAATAAAG ATGAAGTATT TGACGAAAAG TGTTTCAGTG TTGATGAAAT AGTACTACCT 
GATCCCCCTG TGCACCTTAA CTGGACTCTG CTAAATACTA GTCAAACTGG GATCCATGGG 
GATATTCAAG TACGATGGGA TCCACCACCA ACAGCAGATG TTCAGAAAGG ATGGATTACT 
CTGGAGTATG AATTGCAGTA CAAAGAAGTT AATGAGACAA AATGGAAGGA GTTAGAACCC 
AGGCTCTCAA CAGTGGTTCC ACTGTATTCT CTGAAGATGG GAAGAGATTA TGAGATCCGA 
GTCCGATCAA GACAACGTAC CTCCGAAAAG TTTGGGGAGT TCAGTGAAAT CCTCTATGTT 
TCCTTTACTC AAGCAGGCAT TGAATTTGTT CATTGTGCTG AAGAAATCGA GTTTCCCTGG 
TTCTTAGTTG TTGTCTTCGG AGTGTGTGGG CTGGCCGTAA CAGCGATCTT AATCCTGTTG 
TCTAAACAGC CAAGGTTAAA AATGCTGATT TTTCCTCCTG TGCCAGTTCC AAAGATTAAA 
GGGATTGACC CAGATCTCTT AAAGAAAGGA AAGCTAGATG AAGTGAACTC CATCTTAGCC 
AGCCATGACA ACTACAAGAC ACAGCTATAC AATGATGACT TGTGGGTTGA GTTTATTGAA 
TTGGACATAG ATGACTCCGA TGAAAAGAAC AGAGTCTCAG ATACTGACAG GCTCCTGAGT 
GACGATCATC TGAAGTCACA CAGTTGCTTG GGAGCCAAGG ATGATGATTC TGGACGTGCC 
AGTTGTTATG AACCAGATAT TCCAGAGACA GACTTCAGTG CAAGCGACAC ATGTGATGCC 
ATCTCTGATA TTGATCAGTT CAAGAAGGTA ACTGAAAAAG AAGAGGATCT CTTGTGCCTT 
CATAGGAAAG ATGATGTTGA GGCACTTCAA AGTCTTGCCA ACACAGATAC CCAACAGCCG 
CATACTAGTA CTCAGTCTGA AAGCAGAGAG TCATGGCCAC CTTTTGCAGA CAGCACTGAC 
TCAGCTAATC CATCAGTCCA AACTCAGCTA AGTAACCAGA ATTCCCTGAC AAACACTGAC 
TTCTATGCTC AAGTGAGTGA TATTACTCCT GCTGGAAGTG TTGTACTTTC TCCAGGGCAG 
AAATCCAAGG TGGGAAGAGC ACAGTGTGAA AGCTGCACAG AACAAAACTT CACCATGGAC 
AATGCCTATT TCTGTGAGGC AGATGTGAAA AAATGTATTG CTGTGATTTC ACAGGAAGAG 
GATGAGCCGC GTGTTCAGGA GCAAAGCTGT AACGAGGACA CTTACTTCAC CACAGAAAGC 
CTTACCACTA CCGGTATCAA TCTTGGAGCT TCAATGGCAG AAACCCCAAG TATGGAAATG 
CCTGTCCCAG ACTACACTTC TATTCATATT GTTCACTCTC CACAAGGCCT TGTGCTCAAT 
GCAACTGCAC TGCCTGTGCC AGAGAAAGAA TTTAACATGT CTTGTGGCTA TGTGAGCACA 
GACCAGCTGA ACAAAATCAT GCCGTAG