MAFA cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	MAFA
Entrez Gene ID	395881
Full Name	MAF bZIP transcription factor A
Synonyms	L-MAF,MAFL
General protein information	Preferred Names MAF bZIP transcription factor A Names transcription factor MafA bZIP transcription factor L-Maf lens-specific Maf v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A v-maf musculoaponeurotic fibrosarcoma oncogene homolog A
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_205025.1	NP_990356.1	transcription factor MafA

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Mafa	NP_919331.1
Gallus gallus (chicken)	MAFA	NP_990356.1
Danio rerio (zebrafish)	mafa	NP_001076409.1
Bos taurus (cattle)	MAFA	XP_005215337.1
Canis lupus familiaris (dog)	MAFA	XP_003431862.2
Rattus norvegicus (Norway rat)	Mafa	XP_006241965.1
Homo sapiens (human)	MAFA	NP_963883.2
Xenopus tropicalis (tropical clawed frog)	mafa	NP_001027475.1

Gene Ontology
Bibliography

Related articles in PubMed

BMP-induced L-Maf regulates subsequent BMP-independent differentiation of primary lens fibre cells.
Pandit T, Jidigam VK, Gunhaga L
Developmental dynamics : an official publication of the American Association of Anatomists240(8)1917-28(2011 Aug)

L-Maf regulates p27kip1 expression during chick lens fiber differentiation.
Reza HM, Nishi H, Kataoka K, Takahashi Y, Yasuda K
Differentiation; research in biological diversity75(8)737-44(2007 Oct)

MafA has strong cell transforming ability but is a weak transactivator.
Nishizawa M, Kataoka K, Vogt PK
Oncogene22(39)7882-90(2003 Sep)

Genetic variation among chicken lines and mammalian species in specific genes.
Zhou H, Liu W, Lamont SJ
Poultry science80(3)284-8(2001 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results show that before L-Maf induction BMP activity is required for lens specification, whereas after L-Maf up-regulation, the early differentiation of primary lens fibre cells occurs independent of BMP signals.
Title: BMP-induced L-Maf regulates subsequent BMP-independent differentiation of primary lens fibre cells.

Pegulates cell cycle exit of the posterior lens cells by activating cyclin-dependent kinase inhibitor p27 (p27kip1), and thus directs fiber cell differentiation during lens formation in chick.
Title: L-Maf regulates p27kip1 expression during chick lens fiber differentiation.

The following MAFA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAFA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa27720	NM_205025.1 Latest version!	Gallus gallus MAF bZIP transcription factor A (MAFA), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MAFA ( NM_205025.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_990356.1 Gallus gallus MAF bZIP transcription factor A (MAFA), mRNA.

Price & Availability↑

CloneID	OGa27720
Clone ID Related Accession (Same CDS sequence)	NM_205025.1
Accession Version	NM_205025.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 861bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Gallus gallus(chicken)
Product	transcription factor MafA
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF034570.1. On Dec 9, 2006 this sequence version replaced XM_001232433.1. ##Evidence-Data-START## Transcript exon combination :: AF034570.1 [ECO:0000332] ##Evidence-Data-END##

ATGGCCTCGG AGTTGGCCAT GACCGCGGAG CTGCCCACCA GCCCCCTCGC CATCGAATAC 
GTCAACGATT TTGACCTGAT GAAGTTTGAG GTGAAGAAAG AACCGGCGGA GGCCGAGAGG 
CTGTGCCACC GCCTGCCTGC CGGTTCTCTA TCTTCCACCC CTCTCAGCAC CCCGTGCTCC 
TCCGTGCCTT CCTCGCCCAG TTTCTGCGCT CCCAGCCCCG GTGGGCAACC GAGTGCTGGT 
CCCACCGCCG CTCCCCTGGG CTCCAAACCG CAGCTGGAGG AGCTGTATTG GATGTCGGGC 
TACCAACACC ACCTCAACCC CGAAGCGCTC AACTTGACCC CGGAGGATGC TGTGGAAGCG 
TTGATCGGCG CTCCGCACCA CCATCATCAC CACCATCAGA GCTATGAGTC GTTCCGGCCT 
CAGCCCTTTG GGGGCGAGGA GCTGCCCCCG GCCGCCCACC ACCACAACGC CCACCACCAC 
CATCACCACC ACCACCTGCG CTTGGAGGAG AGGTTTTCCG ACGACCAGTT GGTGAGTATG 
TCGGTGCGGG AGCTCAACCG GCAGCTGCGG GGATTCAGCA AGGAGGAGGT GATTCGCCTC 
AAGCAGAACA GGAGGACCTT GAAGAACCGC GGCTACGCGC AGTCCTGTCG CTACAAGCGG 
GTCCAGCAGA GGCACATCCT GGAGAACGAG AAGTGTCAGC TCCAGAGCCA AGTGGAGCAA 
CTCAAGCAAG AAGTTTCCCG TTTGGCCAAG GAGCGGGATC TGTACAAAGA GAAGTACGAG 
AAGTTGGCGG CGCGGGGCTT CCCCCGGGAG CCATCCCCTC CCGCAGCCCC AAAAACTACT 
GCCGCTGACT TCTTCATGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_990356.1
CDS	1126..1986
Translation	MASELAMTAELPTSPLAIEYVNDFDLMKFEVKKEPAEAERLCHRLPAGSLSSTPLSTPCSSVPSSPSFCAPSPGGQPSAGPTAAPLGSKPQLEELYWMSGYQHHLNPEALNLTPEDAVEALIGAPHHHHHHHQSYESFRPQPFGGEELPPAAHHHNAHHHHHHHHLRLEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQNRRTLKNRGYAQSCRYKRVQQRHILENEKCQLQSQVEQLKQEVSRLAKERDLYKEKYEKLAARGFPREPSPPAAPKTTAADFFM

Target ORF information:

RefSeq Version	NM_205025.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus MAF bZIP transcription factor A (MAFA), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_205025.1

ORF Insert Sequence:

ATGGCCTCGG AGTTGGCCAT GACCGCGGAG CTGCCCACCA GCCCCCTCGC CATCGAATAC 
GTCAACGATT TTGACCTGAT GAAGTTTGAG GTGAAGAAAG AACCGGCGGA GGCCGAGAGG 
CTGTGCCACC GCCTGCCTGC CGGTTCTCTA TCTTCCACCC CTCTCAGCAC CCCGTGCTCC 
TCCGTGCCTT CCTCGCCCAG TTTCTGCGCT CCCAGCCCCG GTGGGCAACC GAGTGCTGGT 
CCCACCGCCG CTCCCCTGGG CTCCAAACCG CAGCTGGAGG AGCTGTATTG GATGTCGGGC 
TACCAACACC ACCTCAACCC CGAAGCGCTC AACTTGACCC CGGAGGATGC TGTGGAAGCG 
TTGATCGGCG CTCCGCACCA CCATCATCAC CACCATCAGA GCTATGAGTC GTTCCGGCCT 
CAGCCCTTTG GGGGCGAGGA GCTGCCCCCG GCCGCCCACC ACCACAACGC CCACCACCAC 
CATCACCACC ACCACCTGCG CTTGGAGGAG AGGTTTTCCG ACGACCAGTT GGTGAGTATG 
TCGGTGCGGG AGCTCAACCG GCAGCTGCGG GGATTCAGCA AGGAGGAGGT GATTCGCCTC 
AAGCAGAACA GGAGGACCTT GAAGAACCGC GGCTACGCGC AGTCCTGTCG CTACAAGCGG 
GTCCAGCAGA GGCACATCCT GGAGAACGAG AAGTGTCAGC TCCAGAGCCA AGTGGAGCAA 
CTCAAGCAAG AAGTTTCCCG TTTGGCCAAG GAGCGGGATC TGTACAAAGA GAAGTACGAG 
AAGTTGGCGG CGCGGGGCTT CCCCCGGGAG CCATCCCCTC CCGCAGCCCC AAAAACTACT 
GCCGCTGACT TCTTCATGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

BMP-induced L-Maf regulates subsequent BMP-independent differentiation of primary lens fibre cells.
Developmental dynamics : an official publication of the American Association of Anatomists240(8)1917-28(2011 Aug)
Pandit T,Jidigam VK,Gunhaga L

L-Maf regulates p27kip1 expression during chick lens fiber differentiation.
Differentiation; research in biological diversity75(8)737-44(2007 Oct)
Reza HM,Nishi H,Kataoka K,Takahashi Y,Yasuda K

MafA has strong cell transforming ability but is a weak transactivator.
Oncogene22(39)7882-90(2003 Sep)
Nishizawa M,Kataoka K,Vogt PK

Genetic variation among chicken lines and mammalian species in specific genes.
Poultry science80(3)284-8(2001 Mar)
Zhou H,Liu W,Lamont SJ