IL2 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	IL2
Entrez Gene ID	373958
Full Name	interleukin 2
Synonyms	IL-2,interleukin-2
General protein information	Preferred Names interleukin 2 Names interleukin 2
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
XM_015276098.2	XP_015131584.1	interleukin 2 isoform X1
NM_204153.1	NP_989484.1	interleukin 2 precursor
XM_015276098.1	XP_015131584.1	interleukin 2 isoform X1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Splenic gene expression profiling in White Leghorn layer inoculated with the Salmonella enterica serovar Enteritidis.
Wu G, Liu L, Qi Y, Sun Y, Yang N, Xu G, Zhou H, Li X
Animal genetics46(6)617-26(2015 Dec)

Effects of zearalenone on IL-2, IL-6, and IFN-? mRNA levels in the splenic lymphocytes of chickens.
Wang YC, Deng JL, Xu SW, Peng X, Zuo ZC, Cui HM, Wang Y, Ren ZH
TheScientificWorldJournal2012567327(2012)

Abundance of IFN-? and IFN-? gene transcripts and absence of IL-2 transcripts in the blood of chickens vaccinated with live or inactivated NDV.
Balenovi? M, Savi? V, Ekert Kabalin A, Jurinovi? L, Ragland WL
Acta veterinaria Hungarica59(1)141-8(2011 Mar)

Identification of functional domains of chicken interleukin 2.
Gu J, Ruan X, Huang Z, Chen J, Zhou J
Veterinary immunology and immunopathology134(3-4)230-8(2010 Apr)

Identification of the functional interleukin-2 binding domain of the chicken common cytokine receptor gamma chain.
Gu J, Teng Q, Huang Z, Ruan X, Zhou J
Developmental and comparative immunology34(3)258-63(2010 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

zearalenone affects IL-2, IL-6, and IFN-gamma mRNA levels in the splenic lymphocytes of chickens
Title: Effects of zearalenone on IL-2, IL-6, and IFN-? mRNA levels in the splenic lymphocytes of chickens.

The results show that cells stimulated to produce IFN-alpha and IFN-gamma enter the circulating blood but those stimulated to produce IL-2 do not, or in very low number, and the IFN responses to both vaccines are the same.
Title: Abundance of IFN-? and IFN-? gene transcripts and absence of IL-2 transcripts in the blood of chickens vaccinated with live or inactivated NDV.

The predicted tertiary structure of IL-2 reveals that domain I was positioned in the long A-B loop and the N terminal of Helix B, domain II was mostly situated in Helix C, and domain III was distributed in the C-D loop and Helix D.
Title: Identification of functional domains of chicken interleukin 2.

These data provide experimental evidence for elucidating the interaction between chicken CD132 and IL-2.
Title: Identification of the functional interleukin-2 binding domain of the chicken common cytokine receptor gamma chain.

The following IL2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OGa24397	NM_204153.1 Latest version!	Gallus gallus interleukin 2 (IL2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OGa34998	XM_015276098.2 Latest version!	Gallus gallus interleukin 2 (IL2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00
View Old Accession Versions >>
OGa34998	XM_015276098.1	Gallus gallus interleukin 2 (IL2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IL2 ( NM_204153.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_989484.1 Gallus gallus interleukin 2 (IL2), mRNA.

Price & Availability↑

CloneID	OGa24397
Clone ID Related Accession (Same CDS sequence)	NM_204153.1
Accession Version	NM_204153.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 432bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-20
Organism	Gallus gallus(chicken)
Product	interleukin 2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF033563.1. On Aug 30, 2004 this sequence version replaced XM_420623.1. ##Evidence-Data-START## Transcript exon combination :: AF033563.1, AF017645.1 [ECO:0000332] ##Evidence-Data-END##

ATGATGTGCA AAGTACTGAT CTTTGGCTGT ATTTCGGTAG CAATGCTAAT GACTACAGCT 
TATGGAGCAT CTCTATCATC AGAAAAATGG AAAACTCTTC AAACATTAAT AAAGGATTTA 
GAAATATTGG AAAATATCAA GAATAAGATT CATCTCGAGC TCTACACACC AACTGAGACC 
CAGGAGTGCA CCCAGCAAAC TCTGCAGTGT TACCTGGGAG AAGTGGTTAC TCTGAAGAAA 
GAAACTGAAG ATGACACTGA AATTAAAGAA GAATTTGTAA CTGCTATTCA AAATATCGAA 
AAGAACCTCA AGAGTCTTAC GGGTCTAAAT CACACCGGAA GTGAATGCAA GATCTGTGAA 
GCTAACAACA AGAAAAAATT TCCTGATTTT CTCCATGAAC TGACCAACTT TGTGAGATAT 
CTGCAAAAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_989484.1
CDS	61..492
Translation	MMCKVLIFGCISVAMLMTTAYGASLSSEKWKTLQTLIKDLEILENIKNKIHLELYTPTETQECTQQTLQCYLGEVVTLKKETEDDTEIKEEFVTAIQNIEKNLKSLTGLNHTGSECKICEANNKKKFPDFLHELTNFVRYLQK

Target ORF information:

RefSeq Version	NM_204153.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus interleukin 2 (IL2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_204153.1

ORF Insert Sequence:

ATGATGTGCA AAGTACTGAT CTTTGGCTGT ATTTCGGTAG CAATGCTAAT GACTACAGCT 
TATGGAGCAT CTCTATCATC AGAAAAATGG AAAACTCTTC AAACATTAAT AAAGGATTTA 
GAAATATTGG AAAATATCAA GAATAAGATT CATCTCGAGC TCTACACACC AACTGAGACC 
CAGGAGTGCA CCCAGCAAAC TCTGCAGTGT TACCTGGGAG AAGTGGTTAC TCTGAAGAAA 
GAAACTGAAG ATGACACTGA AATTAAAGAA GAATTTGTAA CTGCTATTCA AAATATCGAA 
AAGAACCTCA AGAGTCTTAC GGGTCTAAAT CACACCGGAA GTGAATGCAA GATCTGTGAA 
GCTAACAACA AGAAAAAATT TCCTGATTTT CTCCATGAAC TGACCAACTT TGTGAGATAT 
CTGCAAAAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IL2 ( XM_015276098.2 ) cDNA ORF clone, Gallus gallus(chicken) -> XP_015131584.1 Gallus gallus interleukin 2 (IL2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OGa34998
Clone ID Related Accession (Same CDS sequence)	XM_015276098.2 , XM_015276098.1
Accession Version	XM_015276098.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 429bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-16
Organism	Gallus gallus(chicken)
Product	interleukin 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006091.5) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XM_015276098.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGTGCA AAGTACTGAT CTTTGGCTGT ATTTCGGTAG CAATGCTAAT GACTACAGCT 
TATGGAGCAT CTCTATCATC AGCAAAAAGG AAACCTCTTC AAACATTAAT AAAGGATTTA 
GAAATATTGG AAAATATCAA GAACATTCAT CTCGAGCTCT ACACACCAAC TGAGACCCAG 
GAGTGCACCC AGCAAACTCT GCAGTGTTAC CTGGGAGAAG TGGTTACTCT GAAGAAAGAA 
ACTGAAGATG ACACTGAAAT TAAAGAAGAA TTTGTAACTG CTATTCAAAA TATCGAAAAG 
AACCTCAAGA GTCTTACGGG TCTAAATCAC ACCGGAAGTG AATGCAAGAT CTGTGAAGCT 
AACAACAAGA AAAAATTTCC TGATTTTCTC CATGAACTGA CCAACTTTGT GAGATATCTG 
CAAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_015131584.1
CDS	444..872
Translation	MMCKVLIFGCISVAMLMTTAYGASLSSAKRKPLQTLIKDLEILENIKNIHLELYTPTETQECTQQTLQCYLGEVVTLKKETEDDTEIKEEFVTAIQNIEKNLKSLTGLNHTGSECKICEANNKKKFPDFLHELTNFVRYLQK

Target ORF information:

RefSeq Version	XM_015276098.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus interleukin 2 (IL2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015276098.2

ORF Insert Sequence:

ATGATGTGCA AAGTACTGAT CTTTGGCTGT ATTTCGGTAG CAATGCTAAT GACTACAGCT 
TATGGAGCAT CTCTATCATC AGCAAAAAGG AAACCTCTTC AAACATTAAT AAAGGATTTA 
GAAATATTGG AAAATATCAA GAACATTCAT CTCGAGCTCT ACACACCAAC TGAGACCCAG 
GAGTGCACCC AGCAAACTCT GCAGTGTTAC CTGGGAGAAG TGGTTACTCT GAAGAAAGAA 
ACTGAAGATG ACACTGAAAT TAAAGAAGAA TTTGTAACTG CTATTCAAAA TATCGAAAAG 
AACCTCAAGA GTCTTACGGG TCTAAATCAC ACCGGAAGTG AATGCAAGAT CTGTGAAGCT 
AACAACAAGA AAAAATTTCC TGATTTTCTC CATGAACTGA CCAACTTTGT GAGATATCTG 
CAAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IL2 ( XM_015276098.1 ) cDNA ORF clone, Gallus gallus(chicken) -> XP_015131584.1 Gallus gallus interleukin 2 (IL2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OGa34998
Clone ID Related Accession (Same CDS sequence)	XM_015276098.2 , XM_015276098.1
Accession Version	XM_015276098.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 429bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-03
Organism	Gallus gallus(chicken)
Product	interleukin 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_001471685.3) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Gallus gallus Annotation Release 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGTGCA AAGTACTGAT CTTTGGCTGT ATTTCGGTAG CAATGCTAAT GACTACAGCT 
TATGGAGCAT CTCTATCATC AGCAAAAAGG AAACCTCTTC AAACATTAAT AAAGGATTTA 
GAAATATTGG AAAATATCAA GAACATTCAT CTCGAGCTCT ACACACCAAC TGAGACCCAG 
GAGTGCACCC AGCAAACTCT GCAGTGTTAC CTGGGAGAAG TGGTTACTCT GAAGAAAGAA 
ACTGAAGATG ACACTGAAAT TAAAGAAGAA TTTGTAACTG CTATTCAAAA TATCGAAAAG 
AACCTCAAGA GTCTTACGGG TCTAAATCAC ACCGGAAGTG AATGCAAGAT CTGTGAAGCT 
AACAACAAGA AAAAATTTCC TGATTTTCTC CATGAACTGA CCAACTTTGT GAGATATCTG 
CAAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_015131584.1
CDS	335..763
Translation	MMCKVLIFGCISVAMLMTTAYGASLSSAKRKPLQTLIKDLEILENIKNIHLELYTPTETQECTQQTLQCYLGEVVTLKKETEDDTEIKEEFVTAIQNIEKNLKSLTGLNHTGSECKICEANNKKKFPDFLHELTNFVRYLQK

Target ORF information:

RefSeq Version	XM_015276098.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus interleukin 2 (IL2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015276098.1

ORF Insert Sequence:

ATGATGTGCA AAGTACTGAT CTTTGGCTGT ATTTCGGTAG CAATGCTAAT GACTACAGCT 
TATGGAGCAT CTCTATCATC AGCAAAAAGG AAACCTCTTC AAACATTAAT AAAGGATTTA 
GAAATATTGG AAAATATCAA GAACATTCAT CTCGAGCTCT ACACACCAAC TGAGACCCAG 
GAGTGCACCC AGCAAACTCT GCAGTGTTAC CTGGGAGAAG TGGTTACTCT GAAGAAAGAA 
ACTGAAGATG ACACTGAAAT TAAAGAAGAA TTTGTAACTG CTATTCAAAA TATCGAAAAG 
AACCTCAAGA GTCTTACGGG TCTAAATCAC ACCGGAAGTG AATGCAAGAT CTGTGAAGCT 
AACAACAAGA AAAAATTTCC TGATTTTCTC CATGAACTGA CCAACTTTGT GAGATATCTG 
CAAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Splenic gene expression profiling in White Leghorn layer inoculated with the Salmonella enterica serovar Enteritidis.
Animal genetics46(6)617-26(2015 Dec)
Wu G,Liu L,Qi Y,Sun Y,Yang N,Xu G,Zhou H,Li X

Effects of zearalenone on IL-2, IL-6, and IFN-? mRNA levels in the splenic lymphocytes of chickens.
TheScientificWorldJournal2012567327(2012)
Wang YC,Deng JL,Xu SW,Peng X,Zuo ZC,Cui HM,Wang Y,Ren ZH

Abundance of IFN-? and IFN-? gene transcripts and absence of IL-2 transcripts in the blood of chickens vaccinated with live or inactivated NDV.
Acta veterinaria Hungarica59(1)141-8(2011 Mar)
Balenovi? M,Savi? V,Ekert Kabalin A,Jurinovi? L,Ragland WL

Identification of functional domains of chicken interleukin 2.
Veterinary immunology and immunopathology134(3-4)230-8(2010 Apr)
Gu J,Ruan X,Huang Z,Chen J,Zhou J

Identification of the functional interleukin-2 binding domain of the chicken common cytokine receptor gamma chain.
Developmental and comparative immunology34(3)258-63(2010 Mar)
Gu J,Teng Q,Huang Z,Ruan X,Zhou J

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IL2 cDNA ORF clone, Gallus gallus(chicken)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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