GPX2 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	GPX2
Entrez Gene ID	100857454
Full Name	glutathione peroxidase 2
General protein information	Preferred Names glutathione peroxidase 2 Names glutathione peroxidase 2 glutathione peroxidase 2 (gastrointestinal)
Gene Type	protein-coding
Organism	Gallus gallus(chicken)
Summary	The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is predominantly expressed in the gastrointestinal tract, is localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. It is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. [provided by RefSeq, Jul 2016].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001277854.1	NP_001264783.1	glutathione peroxidase 2
NM_001277854.2	NP_001264783.2	glutathione peroxidase 2

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Gpx2	NP_899653.2
Homo sapiens (human)	GPX2	NP_002074.2
Gallus gallus (chicken)	GPX2	NP_001264783.1
Bos taurus (cattle)	GPX2	NP_001156611.1
Xenopus tropicalis (tropical clawed frog)	gpx2	NP_001243244.1
Mus musculus (house mouse)	Gpx2	NP_109602.2
Pan troglodytes (chimpanzee)	GPX2	NP_001108606.1
	GPX2	NP_001108609.1
Canis lupus familiaris (dog)	GPX2	NP_001108607.1

Gene Ontology
Bibliography

Related articles in PubMed

Dietary Selenium Status Regulates the Transcriptions of Selenoproteome and Activities of Selenoenzymes in Chicken Kidney at Low or Super-nutritional Levels.
Xu JX, Zhang C, Cao CY, Zhu SY, Li H, Sun YC, Li JL
Biological trace element research170(2)438-48(2016 Apr)

Composition and evolution of the vertebrate and mammalian selenoproteomes.
Mariotti M, Ridge PG, Zhang Y, Lobanov AV, Pringle TH, Guigo R, Hatfield DL, Gladyshev VN
PloS one7(3)e33066(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Dietary low Se downregulated the mRNA expressions of Gpx1-4, Txnrd3, Sepn1, Selw, Sepx1, Selh, and SEPSECS.
Title: Dietary Selenium Status Regulates the Transcriptions of Selenoproteome and Activities of Selenoenzymes in Chicken Kidney at Low or Super-nutritional Levels.

The following GPX2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GPX2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa26488	NM_001277854.1 Latest version!	Gallus gallus glutathione peroxidase 2 (GPX2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OGa153261	NM_001277854.2 Latest version!	Gallus gallus glutathione peroxidase 2 (GPX2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GPX2 ( NM_001277854.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001264783.1 Gallus gallus glutathione peroxidase 2 (GPX2), mRNA.

Price & Availability↑

CloneID	OGa26488
Clone ID Related Accession (Same CDS sequence)	NM_001277854.1
Accession Version	NM_001277854.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-06-25
Organism	Gallus gallus(chicken)
Product	glutathione peroxidase 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX273422.4 and BX273421.3. On Apr 24, 2013 this sequence version replaced XM_003641276.1. ##Evidence-Data-START## Transcript exon combination :: BX273422.4, BX273421.3 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2201357, SAMEA2201359 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGCGTCC CCATCGCCAA GTCCTTCTAC GACCTCAGTG CCACCTCCTT GCAGGGGGAG 
AAGGTGGACT TCAACGTCTT CCGCGGGCGG GTGGTCCTCA TCGAGAACGT GGCGTCGCTC 
TGAGGCACCA CGGTGAGGGA TTACACCCAG CTCAACCAGC TGCAGGCACG CTACCCACGG 
CGGCTGGTGG TGCTGGGCTT CCCCTGCAAC CAGTTCGGCT ACCAGGAGAA CGGCACCAAC 
GAGGAGATCC TCAACTGCCT CAAGCACGTG CGGCCGGGGG GCGGCTTCGA GCCCAACTTC 
ACCCTGTTCC AGAAGTGCCA GGTGAACGGG AAGGACACCC ACCCCGTCTT CGCCTACCTG 
AAGGCCCACC TGCCCGCCCC CGTGGACGAG GCAGACCACC TGATGGCCGA ACCCCGCTTC 
CTGGTGTGGA GCCCTGTGAG GCGCTCCGAC ATCTCCTGGA ACTTTGAGAA GTTCCTGGTG 
GGGCCCGAGG GGGAACCTTT CCGCCGCTAC AGCCCTCGCC TGCCCACCAC CCAGATAGAG 
CCTGACATCC AGCGCCTCCT CAAGCTGGCC AAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001264783.1
CDS	5..580
Translation	MSVPIAKSFYDLSATSLQGEKVDFNVFRGRVVLIENVASL*GTTVRDYTQLNQLQARYPRRLVVLGFPCNQFGYQENGTNEEILNCLKHVRPGGGFEPNFTLFQKCQVNGKDTHPVFAYLKAHLPAPVDEADHLMAEPRFLVWSPVRRSDISWNFEKFLVGPEGEPFRRYSPRLPTTQIEPDIQRLLKLAK

Target ORF information:

RefSeq Version	NM_001277854.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus glutathione peroxidase 2 (GPX2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001277854.1

ORF Insert Sequence:

ATGAGCGTCC CCATCGCCAA GTCCTTCTAC GACCTCAGTG CCACCTCCTT GCAGGGGGAG 
AAGGTGGACT TCAACGTCTT CCGCGGGCGG GTGGTCCTCA TCGAGAACGT GGCGTCGCTC 
TGAGGCACCA CGGTGAGGGA TTACACCCAG CTCAACCAGC TGCAGGCACG CTACCCACGG 
CGGCTGGTGG TGCTGGGCTT CCCCTGCAAC CAGTTCGGCT ACCAGGAGAA CGGCACCAAC 
GAGGAGATCC TCAACTGCCT CAAGCACGTG CGGCCGGGGG GCGGCTTCGA GCCCAACTTC 
ACCCTGTTCC AGAAGTGCCA GGTGAACGGG AAGGACACCC ACCCCGTCTT CGCCTACCTG 
AAGGCCCACC TGCCCGCCCC CGTGGACGAG GCAGACCACC TGATGGCCGA ACCCCGCTTC 
CTGGTGTGGA GCCCTGTGAG GCGCTCCGAC ATCTCCTGGA ACTTTGAGAA GTTCCTGGTG 
GGGCCCGAGG GGGAACCTTT CCGCCGCTAC AGCCCTCGCC TGCCCACCAC CCAGATAGAG 
CCTGACATCC AGCGCCTCCT CAAGCTGGCC AAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GPX2 ( NM_001277854.2 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001264783.2 Gallus gallus glutathione peroxidase 2 (GPX2), mRNA.

Price & Availability↑

CloneID	OGa153261
Clone ID Related Accession (Same CDS sequence)	NM_001277854.2
Accession Version	NM_001277854.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-17
Organism	Gallus gallus(chicken)
Product	glutathione peroxidase 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AADN05000685.1. On Jun 18, 2018 this sequence version replaced NM_001277854.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BX273422.4, BX273421.3 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGCGTCC CCATCGCCAA GTCCTTCTAC GACCTCAGTG CCACCTCCTT GCAGGGGGAG 
AAGGTGGACT TCAACGTCTT CCGCGGGCGG GTGGTCCTCA TCGAGAACGT GGCGTCGCTC 
TGAGGCACCA CGGTGAGGGA TTACACCCAG CTCAACCAGC TGCAGGCACG CTACCCACGG 
CGGCTGGTGG TGCTGGGCTT CCCCTGCAAC CAGTTCGGCT ACCAGGAGAA CGGCACCAAC 
GAGGAGATCC TCAACTGCCT CAAGCACGTG CGGCCGGGGG GCGGCTTCGA GCCCAACTTC 
ACCCTGTTCC AGAAGTGCCA GGTGAACGGG AAGGACACCC ACCCCGTCTT CGCCTACCTG 
AAGGCCCACC TGCCCGCCCC CGTGGACGAG GCAGACCACC TGATGGCCGA ACCCCGCTTC 
CTGGTGTGGA GCCCTGTGAG GCGCTCCGAC ATCTCCTGGA ACTTTGAGAA GTTCCTGGTG 
GGGCCCGAGG GGGAACCTTT CCGCCGCTAC AGCCCTCGCC TGCCCACCGC CCAGATAGAG 
CCTGACATCC AGCGCCTCCT CAAGCTGGCC AAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001264783.2
CDS	5..580
Translation	MSVPIAKSFYDLSATSLQGEKVDFNVFRGRVVLIENVASL*GTTVRDYTQLNQLQARYPRRLVVLGFPCNQFGYQENGTNEEILNCLKHVRPGGGFEPNFTLFQKCQVNGKDTHPVFAYLKAHLPAPVDEADHLMAEPRFLVWSPVRRSDISWNFEKFLVGPEGEPFRRYSPRLPTAQIEPDIQRLLKLAK

Target ORF information:

RefSeq Version	NM_001277854.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus glutathione peroxidase 2 (GPX2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001277854.2

ORF Insert Sequence:

ATGAGCGTCC CCATCGCCAA GTCCTTCTAC GACCTCAGTG CCACCTCCTT GCAGGGGGAG 
AAGGTGGACT TCAACGTCTT CCGCGGGCGG GTGGTCCTCA TCGAGAACGT GGCGTCGCTC 
TGAGGCACCA CGGTGAGGGA TTACACCCAG CTCAACCAGC TGCAGGCACG CTACCCACGG 
CGGCTGGTGG TGCTGGGCTT CCCCTGCAAC CAGTTCGGCT ACCAGGAGAA CGGCACCAAC 
GAGGAGATCC TCAACTGCCT CAAGCACGTG CGGCCGGGGG GCGGCTTCGA GCCCAACTTC 
ACCCTGTTCC AGAAGTGCCA GGTGAACGGG AAGGACACCC ACCCCGTCTT CGCCTACCTG 
AAGGCCCACC TGCCCGCCCC CGTGGACGAG GCAGACCACC TGATGGCCGA ACCCCGCTTC 
CTGGTGTGGA GCCCTGTGAG GCGCTCCGAC ATCTCCTGGA ACTTTGAGAA GTTCCTGGTG 
GGGCCCGAGG GGGAACCTTT CCGCCGCTAC AGCCCTCGCC TGCCCACCGC CCAGATAGAG 
CCTGACATCC AGCGCCTCCT CAAGCTGGCC AAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dietary Selenium Status Regulates the Transcriptions of Selenoproteome and Activities of Selenoenzymes in Chicken Kidney at Low or Super-nutritional Levels.
Biological trace element research170(2)438-48(2016 Apr)
Xu JX,Zhang C,Cao CY,Zhu SY,Li H,Sun YC,Li JL

Composition and evolution of the vertebrate and mammalian selenoproteomes.
PloS one7(3)e33066(2012)
Mariotti M,Ridge PG,Zhang Y,Lobanov AV,Pringle TH,Guigo R,Hatfield DL,Gladyshev VN

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

GPX2 cDNA ORF clone, Gallus gallus(chicken)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報