CecA1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	CecA1
Entrez Gene ID	43596
Full Name	Cecropin A1
Synonyms	CEC,CG1365,Cec,Cec A1,Cec-A1,CecA,DIM 25,Dmel\CG1365,cec,cecA,cecA1,crpA1
General protein information	Preferred Names Cecropin A1 Names CG1365 gene product from transcript CG1365-RA CG1365-PA CecA1-PA Cecropin-A1/A2 precursor CecropinA cecropin cecropin A cecropin A1 cecropin-A cecropin-A1 cecropinA1
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3R Map Location: 99E2-99E2

mRNA and Protein(s)

mRNA	Protein	Name
NM_079849.4	NP_524588.1	cecropin A1

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	CecC	NP_524591.1
Drosophila melanogaster (fruit fly)	CecA1	NP_524588.1
Drosophila melanogaster (fruit fly)	CecA2	NP_524589.1
Drosophila melanogaster (fruit fly)	CecB	NP_524590.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate that in response to infection Drosophila egg expressed several immune genes including AttacinA (CG10146), CecropinA1 (CG1365) and CecropinB (CG1878).
Title: Immune competence in insect eggs depends on the extraembryonic serosa.

The functionality of CecA1 ARE relies on its ability to recruit TIS11 protein, which accelerates CecA1 mRNA deadenylation and decay
Title: Post-transcriptional Regulation of Genes Encoding Anti-microbial Peptides in Drosophila.

Gene was induced by the G(+) bacteria Micrococcus luteus and Staphylococcus aureus, but not by other G(+) or G(-) bacteria.
Title: Differential activation of the NF-kappaB-like factors Relish and Dif in Drosophila melanogaster by fungi and Gram-positive bacteria.

high levels of CecA1 antimicrobial peptide gene expression in response to infection
Title: Functional characterization of a novel promoter element required for an innate immune response in Drosophila.

The following CecA1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CecA1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa06631	NM_079849.4 Latest version!	Drosophila melanogaster cecropin A1 (CecA1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CecA1 ( NM_079849.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_524588.1 Drosophila melanogaster cecropin A1 (CecA1), mRNA.

Price & Availability↑

CloneID	OFa06631
Clone ID Related Accession (Same CDS sequence)	NM_079849.4
Accession Version	NM_079849.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 192bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	cecropin A1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jul 15, 2014 this sequence version replaced NM_079849.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGAACTTCT ACAACATCTT CGTTTTCGTC GCTCTCATTC TGGCCATCAC CATTGGACAA 
TCGGAAGCTG GGTGGCTGAA GAAAATTGGC AAGAAAATCG AACGCGTTGG TCAGCACACT 
CGGGATGCCA CAATCCAGGG ACTGGGAATC GCTCAACAAG CCGCCAATGT CGCCGCAACT 
GCCCGAGGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_524588.1
CDS	75..266
Translation	MNFYNIFVFVALILAITIGQSEAGWLKKIGKKIERVGQHTRDATIQGLGIAQQAANVAATARG

Target ORF information:

RefSeq Version	NM_079849.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster cecropin A1 (CecA1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_079849.4

ORF Insert Sequence:

ATGAACTTCT ACAACATCTT CGTTTTCGTC GCTCTCATTC TGGCCATCAC CATTGGACAA 
TCGGAAGCTG GGTGGCTGAA GAAAATTGGC AAGAAAATCG AACGCGTTGG TCAGCACACT 
CGGGATGCCA CAATCCAGGG ACTGGGAATC GCTCAACAAG CCGCCAATGT CGCCGCAACT 
GCCCGAGGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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CecA1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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