Rab7 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rab7
Entrez Gene ID	42841
Full Name	CG5915 gene product from transcript CG5915-RA
Synonyms	AAF56218,CG5915,DRAB7,DRab7,Dm Rab7,DmRab7,Dmel\CG5915,Drab7,O76742,RAB7,Rab-7,Rab-r7,Rab7A,dRab7,drab7,rab7
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3R Map Location: 95D5-95D5

mRNA and Protein(s)

mRNA	Protein	Name
NM_001260347.1	NP_001247276.1	Rab7, isoform B
NM_001260348.2	NP_001247277.1	Rab7, isoform C
NM_079748.4	NP_524472.1	Rab7, isoform A

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	zgc:91909	NP_001002178.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001617	XP_001689335.2
Drosophila melanogaster (fruit fly)	Rab7	NP_524472.1
Arabidopsis thaliana (thale cress)	RABG3d	NP_175638.1
Oryza sativa (rice)	Os01g0227300	NP_001042470.1
Danio rerio (zebrafish)	zgc:100918	NP_001005591.1
Caenorhabditis elegans (roundworm)	rab-7	NP_496549.1
Arabidopsis thaliana (thale cress)	RABG3c	NP_188231.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Regulation of NOTCH signaling by RAB7 and RAB8 requires carboxyl methylation by ICMT.
Title: Regulation of NOTCH signaling by RAB7 and RAB8 requires carboxyl methylation by ICMT.

findings are not consistent with a gain-of-function mechanism. Instead, they indicate a dosage-dependent sensitivity of neurons to rab7-dependent degradation
Title: Charcot-Marie-Tooth 2B mutations in rab7 cause dosage-dependent neurodegeneration due to partial loss of function.

Dmon1 controls recruitment of Rab7 to maturing endosomes in Drosophila.
Title: Dmon1 controls recruitment of Rab7 to maturing endosomes in Drosophila.

The following Rab7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rab7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OFa05873	NM_001260347.1 Latest version!	Drosophila melanogaster Rab7, transcript variant B (Rab7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OFa05873	NM_001260348.2 Latest version!	Drosophila melanogaster Rab7, transcript variant C (Rab7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OFa05873	NM_079748.4 Latest version!	Drosophila melanogaster Rab7, transcript variant A (Rab7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rab7 ( NM_001260347.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001247276.1 Drosophila melanogaster Rab7, transcript variant B (Rab7), mRNA.

Price & Availability↑

CloneID	OFa05873
Clone ID Related Accession (Same CDS sequence)	NM_001260347.1 , NM_001260348.2 , NM_079748.4
Accession Version	NM_001260347.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 624bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Rab7, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTCCGGAC GTAAGAAATC CCTACTGAAA GTCATCATTC TGGGCGACAG CAGTGTGGGC 
AAGACCTCTC TGATGAATCA GTATGTAAAC AAACGCTTCT CCAACCAATA CAAAGCCACG 
ATCGGAGCTG ATTTCTGCAC GAAAGAGGTG GTGGTCAACG ACCGAGTGGT CACAATGCAG 
ATCTGGGACA CTGCTGGTCA GGAACGCTTC CAGTCGCTTG GAGTGGCGTT TTACCGCGGA 
GCCGACTGCT GCGTGCTTGT CTACGATGTG ACGGCGCCCA ACTCGTTCAA GAATCTCGAC 
TCCTGGCGCG ACGAGTTCCT CATACAGGCC AGTCCACGGG ATCCCGATCA CTTCCCCTTC 
GTTGTGTTGG GCAATAAGGT GGATTTGGAC AACCGCCAGG TGTCCACGCG TCGAGCGCAG 
CAATGGTGCC AATCTAAGAA CGATATACCC TACTACGAAA CGTCCGCCAA GGAGGGCATC 
AACGTGGAGA TGGCGTTTCA AGTTATAGCC AAGAATGCGT TAGAGTTGGA GGCGGAGGCT 
GAAGTTATCA ACGATTTCCC CGATCAGATT ACCTTGGGCT CGCAAAACAA TCGTCCTGGC 
AATCCTGACA ACTGTCAGTG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001247276.1
CDS	144..767
Translation	MSGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQNNRPGNPDNCQC

Target ORF information:

RefSeq Version	NM_001260347.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Rab7, transcript variant B (Rab7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001260347.1

ORF Insert Sequence:

ATGTCCGGAC GTAAGAAATC CCTACTGAAA GTCATCATTC TGGGCGACAG CAGTGTGGGC 
AAGACCTCTC TGATGAATCA GTATGTAAAC AAACGCTTCT CCAACCAATA CAAAGCCACG 
ATCGGAGCTG ATTTCTGCAC GAAAGAGGTG GTGGTCAACG ACCGAGTGGT CACAATGCAG 
ATCTGGGACA CTGCTGGTCA GGAACGCTTC CAGTCGCTTG GAGTGGCGTT TTACCGCGGA 
GCCGACTGCT GCGTGCTTGT CTACGATGTG ACGGCGCCCA ACTCGTTCAA GAATCTCGAC 
TCCTGGCGCG ACGAGTTCCT CATACAGGCC AGTCCACGGG ATCCCGATCA CTTCCCCTTC 
GTTGTGTTGG GCAATAAGGT GGATTTGGAC AACCGCCAGG TGTCCACGCG TCGAGCGCAG 
CAATGGTGCC AATCTAAGAA CGATATACCC TACTACGAAA CGTCCGCCAA GGAGGGCATC 
AACGTGGAGA TGGCGTTTCA AGTTATAGCC AAGAATGCGT TAGAGTTGGA GGCGGAGGCT 
GAAGTTATCA ACGATTTCCC CGATCAGATT ACCTTGGGCT CGCAAAACAA TCGTCCTGGC 
AATCCTGACA ACTGTCAGTG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rab7 ( NM_001260348.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001247277.1 Drosophila melanogaster Rab7, transcript variant C (Rab7), mRNA.

Price & Availability↑

CloneID	OFa05873
Clone ID Related Accession (Same CDS sequence)	NM_001260347.1 , NM_001260348.2 , NM_079748.4
Accession Version	NM_001260348.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 624bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Rab7, isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jul 15, 2014 this sequence version replaced NM_001260348.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTCCGGAC GTAAGAAATC CCTACTGAAA GTCATCATTC TGGGCGACAG CAGTGTGGGC 
AAGACCTCTC TGATGAATCA GTATGTAAAC AAACGCTTCT CCAACCAATA CAAAGCCACG 
ATCGGAGCTG ATTTCTGCAC GAAAGAGGTG GTGGTCAACG ACCGAGTGGT CACAATGCAG 
ATCTGGGACA CTGCTGGTCA GGAACGCTTC CAGTCGCTTG GAGTGGCGTT TTACCGCGGA 
GCCGACTGCT GCGTGCTTGT CTACGATGTG ACGGCGCCCA ACTCGTTCAA GAATCTCGAC 
TCCTGGCGCG ACGAGTTCCT CATACAGGCC AGTCCACGGG ATCCCGATCA CTTCCCCTTC 
GTTGTGTTGG GCAATAAGGT GGATTTGGAC AACCGCCAGG TGTCCACGCG TCGAGCGCAG 
CAATGGTGCC AATCTAAGAA CGATATACCC TACTACGAAA CGTCCGCCAA GGAGGGCATC 
AACGTGGAGA TGGCGTTTCA AGTTATAGCC AAGAATGCGT TAGAGTTGGA GGCGGAGGCT 
GAAGTTATCA ACGATTTCCC CGATCAGATT ACCTTGGGCT CGCAAAACAA TCGTCCTGGC 
AATCCTGACA ACTGTCAGTG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001247277.1
CDS	155..778
Translation	MSGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQNNRPGNPDNCQC

Target ORF information:

RefSeq Version	NM_001260348.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Rab7, transcript variant C (Rab7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001260348.2

ORF Insert Sequence:

ATGTCCGGAC GTAAGAAATC CCTACTGAAA GTCATCATTC TGGGCGACAG CAGTGTGGGC 
AAGACCTCTC TGATGAATCA GTATGTAAAC AAACGCTTCT CCAACCAATA CAAAGCCACG 
ATCGGAGCTG ATTTCTGCAC GAAAGAGGTG GTGGTCAACG ACCGAGTGGT CACAATGCAG 
ATCTGGGACA CTGCTGGTCA GGAACGCTTC CAGTCGCTTG GAGTGGCGTT TTACCGCGGA 
GCCGACTGCT GCGTGCTTGT CTACGATGTG ACGGCGCCCA ACTCGTTCAA GAATCTCGAC 
TCCTGGCGCG ACGAGTTCCT CATACAGGCC AGTCCACGGG ATCCCGATCA CTTCCCCTTC 
GTTGTGTTGG GCAATAAGGT GGATTTGGAC AACCGCCAGG TGTCCACGCG TCGAGCGCAG 
CAATGGTGCC AATCTAAGAA CGATATACCC TACTACGAAA CGTCCGCCAA GGAGGGCATC 
AACGTGGAGA TGGCGTTTCA AGTTATAGCC AAGAATGCGT TAGAGTTGGA GGCGGAGGCT 
GAAGTTATCA ACGATTTCCC CGATCAGATT ACCTTGGGCT CGCAAAACAA TCGTCCTGGC 
AATCCTGACA ACTGTCAGTG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rab7 ( NM_079748.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_524472.1 Drosophila melanogaster Rab7, transcript variant A (Rab7), mRNA.

Price & Availability↑

CloneID	OFa05873
Clone ID Related Accession (Same CDS sequence)	NM_001260347.1 , NM_001260348.2 , NM_079748.4
Accession Version	NM_079748.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 624bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Rab7, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jul 15, 2014 this sequence version replaced NM_079748.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTCCGGAC GTAAGAAATC CCTACTGAAA GTCATCATTC TGGGCGACAG CAGTGTGGGC 
AAGACCTCTC TGATGAATCA GTATGTAAAC AAACGCTTCT CCAACCAATA CAAAGCCACG 
ATCGGAGCTG ATTTCTGCAC GAAAGAGGTG GTGGTCAACG ACCGAGTGGT CACAATGCAG 
ATCTGGGACA CTGCTGGTCA GGAACGCTTC CAGTCGCTTG GAGTGGCGTT TTACCGCGGA 
GCCGACTGCT GCGTGCTTGT CTACGATGTG ACGGCGCCCA ACTCGTTCAA GAATCTCGAC 
TCCTGGCGCG ACGAGTTCCT CATACAGGCC AGTCCACGGG ATCCCGATCA CTTCCCCTTC 
GTTGTGTTGG GCAATAAGGT GGATTTGGAC AACCGCCAGG TGTCCACGCG TCGAGCGCAG 
CAATGGTGCC AATCTAAGAA CGATATACCC TACTACGAAA CGTCCGCCAA GGAGGGCATC 
AACGTGGAGA TGGCGTTTCA AGTTATAGCC AAGAATGCGT TAGAGTTGGA GGCGGAGGCT 
GAAGTTATCA ACGATTTCCC CGATCAGATT ACCTTGGGCT CGCAAAACAA TCGTCCTGGC 
AATCCTGACA ACTGTCAGTG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_524472.1
CDS	190..813
Translation	MSGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQNNRPGNPDNCQC

Target ORF information:

RefSeq Version	NM_079748.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Rab7, transcript variant A (Rab7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_079748.4

ORF Insert Sequence:

ATGTCCGGAC GTAAGAAATC CCTACTGAAA GTCATCATTC TGGGCGACAG CAGTGTGGGC 
AAGACCTCTC TGATGAATCA GTATGTAAAC AAACGCTTCT CCAACCAATA CAAAGCCACG 
ATCGGAGCTG ATTTCTGCAC GAAAGAGGTG GTGGTCAACG ACCGAGTGGT CACAATGCAG 
ATCTGGGACA CTGCTGGTCA GGAACGCTTC CAGTCGCTTG GAGTGGCGTT TTACCGCGGA 
GCCGACTGCT GCGTGCTTGT CTACGATGTG ACGGCGCCCA ACTCGTTCAA GAATCTCGAC 
TCCTGGCGCG ACGAGTTCCT CATACAGGCC AGTCCACGGG ATCCCGATCA CTTCCCCTTC 
GTTGTGTTGG GCAATAAGGT GGATTTGGAC AACCGCCAGG TGTCCACGCG TCGAGCGCAG 
CAATGGTGCC AATCTAAGAA CGATATACCC TACTACGAAA CGTCCGCCAA GGAGGGCATC 
AACGTGGAGA TGGCGTTTCA AGTTATAGCC AAGAATGCGT TAGAGTTGGA GGCGGAGGCT 
GAAGTTATCA ACGATTTCCC CGATCAGATT ACCTTGGGCT CGCAAAACAA TCGTCCTGGC 
AATCCTGACA ACTGTCAGTG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Rab7 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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