ftz cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	ftz
Entrez Gene ID	40834
Full Name	fushi tarazu
Synonyms	BG:DS07876.1,CG2047,Dm-Ftz,Dm-ftz,DmFtz,Dmel\CG2047,Dmftz,FTZ,Ftz,Ual,l(3)84Ag
General protein information	Preferred Names fushi tarazu Names CG2047 gene product from transcript CG2047-RA CG2047-PA Fushi-Tarazu Ultra-abdominal-like ftz-PA fushitarazu
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3R Map Location: 84A6-84A6\|3-47.5 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_058150.3	NP_477498.1	fushi tarazu

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Comparative analysis of enhancers containing Ftz/Ftz-F1 binding sites that were or were not bona fide targets in vivo suggested that GAF negatively regulates enhancers that contain Ftz/Ftz-F1 binding sites but are not actually utilized.
Title: Activation of Ftz-F1-Responsive Genes through Ftz/Ftz-F1 Dependent Enhancers.

Evolutionary acquisition of the LXXLL motif specialized Ftz for segmentation, while strengthening the Ftz/Ftz-F1 interaction led to degeneration of the YPWM motif and loss of homeotic activity.
Title: Cofactor-interaction motifs and the cooption of a homeotic Hox protein into the segmentation pathway of Drosophila melanogaster.

Contrasting responses of different downstream targets to Runt in the presence or absence of Ftz is thus central to the combinatorial logic of the pair-rule to segment-polarity transition.
Title: Ftz modulates Runt-dependent activation and repression of segment-polarity gene transcription.

FTZ(delta151-209) is a hyperactive FTZ molecule; the region encompassing amino acids 151-209 of FTZ is required in some manner for repression of FTZ activity
Title: Low-level ectopic expression of Fushi tarazu in Drosophila melanogaster results in ftz(Ual/Rpl)-like phenotypes and rescues ftz phenotypes.

influences Ftz-F1 activity by interacting with its AF-2 domain in a manner that mimics a nuclear receptor coactivator
Title: The nuclear receptor Ftz-F1 and homeodomain protein Ftz interact through evolutionarily conserved protein domains.

The following ftz gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ftz cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa04131	NM_058150.3 Latest version!	Drosophila melanogaster fushi tarazu (ftz), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ftz ( NM_058150.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_477498.1 Drosophila melanogaster fushi tarazu (ftz), mRNA.

Price & Availability↑

CloneID	OFa04131
Clone ID Related Accession (Same CDS sequence)	NM_058150.3
Accession Version	NM_058150.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1233bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	fushi tarazu
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jul 15, 2014 this sequence version replaced NM_058150.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCCACCA CAAACAGCCA GAGCCACTAC AGCTACGCCG ACAACATGAA CATGTACAAC 
ATGTATCACC CCCACAGCCT GCCGCCCACC TACTACGATA ATTCAGGCAG CAATGCCTAC 
TATCAGAACA CCTCCAATTA TCAGGGCTAC TATCCCCAGG AGAGTTACTC GGAGAGCTGC 
TACTACTACA ACAATCAGGA GCAGGTGACC ACCCAGACTG TACCGCCCGT GCAACCCACC 
ACCCCGCCGC CCAAGGCCAC CAAGCGCAAG GCCGAAGATG ATGCTGCTTC CATCATCGCC 
GCCGTGGAGG AGCGACCCAG CACACTGAGG GCTCTGCTCA CCAATCCCGT GAAGAAGCTG 
AAGTACACCC CCGACTATTT CTACACAACC GTCGAGCAGG TGAAGAAGGC TCCCGCCGTA 
AGCACCAAGG TCACCGCCAG CCCCGCTCCC AGCTACGACC AAGAGTACGT GACTGTGCCC 
ACGCCCAGCG CCTCCGAGGA TGTCGACTAC TTGGACGTCT ACTCGCCCCA GTCGCAGACG 
CAGAAGCTGA AGAATGGCGA CTTTGCCACC CCTCCGCCAA CCACGCCCAC CTCTCTGCCG 
CCCCTCGAAG GCATCAGCAC GCCACCCCAA TCGCCGGGGG AGAAATCCTC GTCAGCTGTC 
AGCCAGGAGA TCAATCATCG AATTGTGACA GCCCCGAATG GAGCCGGCGA TTTCAATTGG 
TCGCACATCG AGGAGACTTT GGCATCAGAT TGCAAAGACT CGAAACGCAC CCGTCAGACG 
TACACCCGCT ACCAGACCCT GGAGCTCGAG AAGGAGTTCC ACTTCAATAG ATACATCACC 
CGGCGTCGTC GCATCGATAT CGCCAATGCC CTGAGCCTGA GCGAAAGGCA GATCAAGATC 
TGGTTCCAAA ACCGACGCAT GAAGTCGAAG AAGGATCGCA CGCTGGACAG CTCCCCGGAG 
CACTGTGGTG CCGGCTACAC CGCGATGCTG CCGCCACTGG AGGCCACAAG CACCGCCACC 
ACCGGGGCAC CATCGGTGCC AGTGCCCATG TACCACCACC ACCAAACCAC CGCCGCCTAC 
CCCGCTTACA GCCACAGTCA CAGTCATGGT TATGGCCTGC TCAATGATTA CCCTCAGCAG 
CAGACCCACC AGCAGTACGA TGCCTACCCG CAGCAGTACC AACATCAGTG CAGCTACCAG 
CAACATCCAC AGGACCTCTA CCATCTGTCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_477498.1
CDS	71..1303
Translation	MATTNSQSHYSYADNMNMYNMYHPHSLPPTYYDNSGSNAYYQNTSNYQGYYPQESYSESCYYYNNQEQVTTQTVPPVQPTTPPPKATKRKAEDDAASIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTVEQVKKAPAVSTKVTASPAPSYDQEYVTVPTPSASEDVDYLDVYSPQSQTQKLKNGDFATPPPTTPTSLPPLEGISTPPQSPGEKSSSAVSQEINHRIVTAPNGAGDFNWSHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKDRTLDSSPEHCGAGYTAMLPPLEATSTATTGAPSVPVPMYHHHQTTAAYPAYSHSHSHGYGLLNDYPQQQTHQQYDAYPQQYQHQCSYQQHPQDLYHLS

Target ORF information:

RefSeq Version	NM_058150.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster fushi tarazu (ftz), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_058150.3

ORF Insert Sequence:

ATGGCCACCA CAAACAGCCA GAGCCACTAC AGCTACGCCG ACAACATGAA CATGTACAAC 
ATGTATCACC CCCACAGCCT GCCGCCCACC TACTACGATA ATTCAGGCAG CAATGCCTAC 
TATCAGAACA CCTCCAATTA TCAGGGCTAC TATCCCCAGG AGAGTTACTC GGAGAGCTGC 
TACTACTACA ACAATCAGGA GCAGGTGACC ACCCAGACTG TACCGCCCGT GCAACCCACC 
ACCCCGCCGC CCAAGGCCAC CAAGCGCAAG GCCGAAGATG ATGCTGCTTC CATCATCGCC 
GCCGTGGAGG AGCGACCCAG CACACTGAGG GCTCTGCTCA CCAATCCCGT GAAGAAGCTG 
AAGTACACCC CCGACTATTT CTACACAACC GTCGAGCAGG TGAAGAAGGC TCCCGCCGTA 
AGCACCAAGG TCACCGCCAG CCCCGCTCCC AGCTACGACC AAGAGTACGT GACTGTGCCC 
ACGCCCAGCG CCTCCGAGGA TGTCGACTAC TTGGACGTCT ACTCGCCCCA GTCGCAGACG 
CAGAAGCTGA AGAATGGCGA CTTTGCCACC CCTCCGCCAA CCACGCCCAC CTCTCTGCCG 
CCCCTCGAAG GCATCAGCAC GCCACCCCAA TCGCCGGGGG AGAAATCCTC GTCAGCTGTC 
AGCCAGGAGA TCAATCATCG AATTGTGACA GCCCCGAATG GAGCCGGCGA TTTCAATTGG 
TCGCACATCG AGGAGACTTT GGCATCAGAT TGCAAAGACT CGAAACGCAC CCGTCAGACG 
TACACCCGCT ACCAGACCCT GGAGCTCGAG AAGGAGTTCC ACTTCAATAG ATACATCACC 
CGGCGTCGTC GCATCGATAT CGCCAATGCC CTGAGCCTGA GCGAAAGGCA GATCAAGATC 
TGGTTCCAAA ACCGACGCAT GAAGTCGAAG AAGGATCGCA CGCTGGACAG CTCCCCGGAG 
CACTGTGGTG CCGGCTACAC CGCGATGCTG CCGCCACTGG AGGCCACAAG CACCGCCACC 
ACCGGGGCAC CATCGGTGCC AGTGCCCATG TACCACCACC ACCAAACCAC CGCCGCCTAC 
CCCGCTTACA GCCACAGTCA CAGTCATGGT TATGGCCTGC TCAATGATTA CCCTCAGCAG 
CAGACCCACC AGCAGTACGA TGCCTACCCG CAGCAGTACC AACATCAGTG CAGCTACCAG 
CAACATCCAC AGGACCTCTA CCATCTGTCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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ftz cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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