lush cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	lush
Entrez Gene ID	40136
Full Name	CG8807 gene product from transcript CG8807-RA
Synonyms	76a,76c,76c(LUSH),CG8807,DmelObp76a,Dmel\CG8807,LUSH,Lush,Obp76a,obp76a
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3L Map Location: 76B9-76B9

mRNA and Protein(s)

mRNA	Protein	Name
NM_079438.3	NP_524162.1	lush, isoform A
NM_001169997.1	NP_001163468.1	lush, isoform B

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	OBP5	XP_318661.2
Anopheles gambiae (African malaria mosquito)	OBP4	XP_314462.2
Drosophila melanogaster (fruit fly)	lush	NP_001163468.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the ligand-binding cavity of LUSH protein can accommodate a variety ligands and pheromones with strong binding interactions
Title: Quantitative analysis of pheromone-binding protein specificity.

the alcohol binding in the LUSH protein is the consequence of three important factors: H-bonding, solvation, and the other noncovalent interaction.
Title: Alcohol binding to the odorant binding protein LUSH: multiple factors affecting binding affinities.

Detection of odorants by olfactory neurons is results from direct activation of odorant receptors by odor molecules; study shows that detection of the 11-cis vaccenyl acetate (cVA), is instead mediated by pheromone-induced conformational shifts in LUSH.
Title: Activation of pheromone-sensitive neurons is mediated by conformational activation of pheromone-binding protein.

genetic interaction between lush and spontaneous activity in 11-cis vaccenyl acetate-sensitive neurons in the absence of pheromone
Title: Drosophila OBP LUSH is required for activity of pheromone-sensitive neurons.

LUSH, a soluble odorant-binding protein, undergoes a major conformational change, triggered by ligands.
Title: Revisiting the odorant-binding protein LUSH of Drosophila melanogaster: evidence for odour recognition and discrimination.

The following lush gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the lush cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa18986	NM_079438.3 Latest version!	Drosophila melanogaster lush, transcript variant A (lush), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OFa18986	NM_001169997.1 Latest version!	Drosophila melanogaster lush, transcript variant B (lush), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

lush ( NM_079438.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_524162.1 Drosophila melanogaster lush, transcript variant A (lush), mRNA.

Price & Availability↑

CloneID	OFa18986
Clone ID Related Accession (Same CDS sequence)	NM_079438.3 , NM_001169997.1
Accession Version	NM_079438.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 462bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	lush, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Dec 17, 2009 this sequence version replaced NM_079438.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGAAGCATT GGAAACGACG CTCTTCCGCT GTTTTCGCGA TCGTCCTGCA AGTGCTGGTA 
CTCCTGCTAC CCGATCCTGC AGTTGCCATG ACGATGGAGC AGTTCTTGAC CTCGCTAGAC 
ATGATCCGCA GTGGCTGTGC GCCGAAGTTT AAGCTCAAAA CAGAAGATCT CGATCGGCTT 
CGCGTGGGTG ATTTCAACTT TCCGCCATCG CAGGATCTTA TGTGCTACAC AAAGTGTGTG 
TCTTTGATGG CGGGCACTGT GAACAAAAAG GGGGAGTTCA ACGCTCCCAA GGCGCTGGCC 
CAACTTCCGC ATCTGGTTCC CCCGGAAATG ATGGAGATGT CCAGGAAATC CGTTGAAGCT 
TGTCGGGATA CGCATAAACA ATTTAAGGAA TCTTGCGAGA GGGTCTACCA GACGGCCAAG 
TGCTTCTCTG AAAACGCCGA TGGGCAGTTC ATGTGGCCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_524162.1
CDS	225..686
Translation	MKHWKRRSSAVFAIVLQVLVLLLPDPAVAMTMEQFLTSLDMIRSGCAPKFKLKTEDLDRLRVGDFNFPPSQDLMCYTKCVSLMAGTVNKKGEFNAPKALAQLPHLVPPEMMEMSRKSVEACRDTHKQFKESCERVYQTAKCFSENADGQFMWP

Target ORF information:

RefSeq Version	NM_079438.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster lush, transcript variant A (lush), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_079438.3

ORF Insert Sequence:

ATGAAGCATT GGAAACGACG CTCTTCCGCT GTTTTCGCGA TCGTCCTGCA AGTGCTGGTA 
CTCCTGCTAC CCGATCCTGC AGTTGCCATG ACGATGGAGC AGTTCTTGAC CTCGCTAGAC 
ATGATCCGCA GTGGCTGTGC GCCGAAGTTT AAGCTCAAAA CAGAAGATCT CGATCGGCTT 
CGCGTGGGTG ATTTCAACTT TCCGCCATCG CAGGATCTTA TGTGCTACAC AAAGTGTGTG 
TCTTTGATGG CGGGCACTGT GAACAAAAAG GGGGAGTTCA ACGCTCCCAA GGCGCTGGCC 
CAACTTCCGC ATCTGGTTCC CCCGGAAATG ATGGAGATGT CCAGGAAATC CGTTGAAGCT 
TGTCGGGATA CGCATAAACA ATTTAAGGAA TCTTGCGAGA GGGTCTACCA GACGGCCAAG 
TGCTTCTCTG AAAACGCCGA TGGGCAGTTC ATGTGGCCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

lush ( NM_001169997.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001163468.1 Drosophila melanogaster lush, transcript variant B (lush), mRNA.

Price & Availability↑

CloneID	OFa18986
Clone ID Related Accession (Same CDS sequence)	NM_079438.3 , NM_001169997.1
Accession Version	NM_001169997.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 462bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	lush, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGAAGCATT GGAAACGACG CTCTTCCGCT GTTTTCGCGA TCGTCCTGCA AGTGCTGGTA 
CTCCTGCTAC CCGATCCTGC AGTTGCCATG ACGATGGAGC AGTTCTTGAC CTCGCTAGAC 
ATGATCCGCA GTGGCTGTGC GCCGAAGTTT AAGCTCAAAA CAGAAGATCT CGATCGGCTT 
CGCGTGGGTG ATTTCAACTT TCCGCCATCG CAGGATCTTA TGTGCTACAC AAAGTGTGTG 
TCTTTGATGG CGGGCACTGT GAACAAAAAG GGGGAGTTCA ACGCTCCCAA GGCGCTGGCC 
CAACTTCCGC ATCTGGTTCC CCCGGAAATG ATGGAGATGT CCAGGAAATC CGTTGAAGCT 
TGTCGGGATA CGCATAAACA ATTTAAGGAA TCTTGCGAGA GGGTCTACCA GACGGCCAAG 
TGCTTCTCTG AAAACGCCGA TGGGCAGTTC ATGTGGCCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001163468.1
CDS	212..673
Translation	MKHWKRRSSAVFAIVLQVLVLLLPDPAVAMTMEQFLTSLDMIRSGCAPKFKLKTEDLDRLRVGDFNFPPSQDLMCYTKCVSLMAGTVNKKGEFNAPKALAQLPHLVPPEMMEMSRKSVEACRDTHKQFKESCERVYQTAKCFSENADGQFMWP

Target ORF information:

RefSeq Version	NM_001169997.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster lush, transcript variant B (lush), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001169997.1

ORF Insert Sequence:

ATGAAGCATT GGAAACGACG CTCTTCCGCT GTTTTCGCGA TCGTCCTGCA AGTGCTGGTA 
CTCCTGCTAC CCGATCCTGC AGTTGCCATG ACGATGGAGC AGTTCTTGAC CTCGCTAGAC 
ATGATCCGCA GTGGCTGTGC GCCGAAGTTT AAGCTCAAAA CAGAAGATCT CGATCGGCTT 
CGCGTGGGTG ATTTCAACTT TCCGCCATCG CAGGATCTTA TGTGCTACAC AAAGTGTGTG 
TCTTTGATGG CGGGCACTGT GAACAAAAAG GGGGAGTTCA ACGCTCCCAA GGCGCTGGCC 
CAACTTCCGC ATCTGGTTCC CCCGGAAATG ATGGAGATGT CCAGGAAATC CGTTGAAGCT 
TGTCGGGATA CGCATAAACA ATTTAAGGAA TCTTGCGAGA GGGTCTACCA GACGGCCAAG 
TGCTTCTCTG AAAACGCCGA TGGGCAGTTC ATGTGGCCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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lush cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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