SP cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	SP
Entrez Gene ID	39494
Full Name	Sex Peptide
Synonyms	ACP,ACP70A,Acp-70A,Acp70,Acp70A,Acp70a,Apc70A,CG17673,Dmel\CG17673,DrmSP,PapB,Spg70,sex peptide
General protein information	Preferred Names Sex Peptide Names CG17673 gene product from transcript CG17673-RA CG17673-PA DrmSP Paragonial-peptide-B SP-PA Sex peptide Sex-Peptide accessory gland peptide 70A accessory gland protein 70A accessory protein 70A sex peptide gene in 70 sexpeptide
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3L Map Location: 70A4-70A4

mRNA and Protein(s)

mRNA	Protein	Name
NM_079333.2	NP_524057.2	Sex peptide

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that female sleep is reduced by male-derived sex Peptide (SP) SP acting through the canonical sex peptide receptor (SPR) within the same neurons responsible for altering other postmating responses (PMRs).
Title: Changes in Female Drosophila Sleep following Mating Are Mediated by SPSN-SAG Neurons.

Results suggested that the SP/SPR-mediated post-mating responses was established in the lineage of the D. melanogaster species group.
Title: Evolution of sex-peptide in Drosophila.

Molecular Functions and Cross-Species Activity of Sex-Peptide in Drosophila
Title: Visualizing Molecular Functions and Cross-Species Activity of Sex-Peptide in Drosophila.

Results reveal a rather flexible sex peptide that lacks a compact folded structure in solution.
Title: NMR studies of the solution conformation of the sex peptide from Drosophila melanogaster.

MIPs likely function as ancestral ligands of SPRs and could place evolutionary constraints on the MIP/SPR class.
Title: Myoinhibiting peptides are the ancestral ligands of the promiscuous Drosophila sex peptide receptor.

The following SP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa18397	NM_079333.2 Latest version!	Drosophila melanogaster Sex peptide (SP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SP ( NM_079333.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_524057.2 Drosophila melanogaster Sex peptide (SP), mRNA.

Price & Availability↑

CloneID	OFa18397
Clone ID Related Accession (Same CDS sequence)	NM_079333.2
Accession Version	NM_079333.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 168bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Sex peptide
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Nov 6, 2002 this sequence version replaced NM_079333.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

1
61
121

ATGAAAACTC TAGCTCTATT CTTGGTTCTC GTTTGCGTAC TCGGCTTGGT CCAGGCCTGG 
GAATGGCCGT GGAATAGGAA GCCTACAAAG TTTCCAATTC CAAGCCCCAA TCCTCGTGAT 
AAGTGGTGCC GTCTTAATTT GGGGCCCGCC TGGGGTGGAA GATGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_524057.2
CDS	4..171
Translation	MKTLALFLVLVCVLGLVQAWEWPWNRKPTKFPIPSPNPRDKWCRLNLGPAWGGRC

Target ORF information:

RefSeq Version	NM_079333.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Sex peptide (SP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_079333.2

ORF Insert Sequence:

1
61
121

ATGAAAACTC TAGCTCTATT CTTGGTTCTC GTTTGCGTAC TCGGCTTGGT CCAGGCCTGG 
GAATGGCCGT GGAATAGGAA GCCTACAAAG TTTCCAATTC CAAGCCCCAA TCCTCGTGAT 
AAGTGGTGCC GTCTTAATTT GGGGCCCGCC TGGGGTGGAA GATGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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SP cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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