Aps cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Aps
Entrez Gene ID	39226
Full Name	CG6391 gene product from transcript CG6391-RC
Synonyms	CG6391,Dmel\CG6391,anon-WO0118547.266
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3L Map Location: 67F1-67F1

mRNA and Protein(s)

mRNA	Protein	Name
NM_168425.3	NP_729639.1	Aps, isoform B
NM_168426.3	NP_729640.1	Aps, isoform C
NM_140164.4	NP_648421.1	Aps, isoform A

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	NUDT3	NP_001244227.1
Danio rerio (zebrafish)	nudt3b	NP_001006034.1
Caenorhabditis elegans (roundworm)	Y92H12BL.5	NP_740784.1
Bos taurus (cattle)	NUDT3	NP_001075935.1
Canis lupus familiaris (dog)	NUDT3	NP_001239318.1
Mus musculus (house mouse)	Nudt3	NP_062811.1
Homo sapiens (human)	NUDT3	NP_006694.1
	NUDT3	XP_001116464.1
Rattus norvegicus (Norway rat)	Nudt3	NP_001019414.1
Drosophila melanogaster (fruit fly)	Aps	NP_648421.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009901	XP_319021.3

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Aps knockdown in Drosophila central nervous system, or the insulin-producing cells induces hyperinsulinemia-like phenotypes, including decrease in circulating trehalose levels as well as decreasing all carbohydrate levels under starvation conditions.
Title: The Obesity-Linked Gene Nudt3 Drosophila Homolog Aps Is Associated With Insulin Signaling.

These data suggest that the redox state of Aps may play a role in controlling its activity by altering its stability, something that could be important for regulating PP-InsP(5) during development.
Title: Oxidation of the diphosphoinositol polyphosphate phosphohydrolase-like Nudix hydrolase Aps from Drosophila melanogaster induces thermolability--A possible regulatory switch?

The following Aps gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Aps cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OFa18188	NM_168426.3 Latest version!	Drosophila melanogaster Aps, transcript variant C (Aps), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OFa18188	NM_168425.3 Latest version!	Drosophila melanogaster Aps, transcript variant B (Aps), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OFa18188	NM_140164.4 Latest version!	Drosophila melanogaster Aps, transcript variant A (Aps), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Aps ( NM_168425.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_729639.1 Drosophila melanogaster Aps, transcript variant B (Aps), mRNA.

Price & Availability↑

CloneID	OFa18188
Clone ID Related Accession (Same CDS sequence)	NM_168425.3 , NM_168426.3 , NM_140164.4
Accession Version	NM_168425.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 534bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Aps, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jan 16, 2013 this sequence version replaced NM_168425.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGTCAAGG AGAAGCCCAA CTCGACTCGC ATCTACGACA AGGATGGATT TAGGCGCCGG 
GCTGCTTGTA TTTGCGTGAA ATCGGAGAAT GAGGCGGAGG TACTCTTGGT AACCTCATCT 
CGTCGCCCGG AGTTGTGGAT CGTTCCAGGA GGCGGCGTTG AACCAGAAGA GGAGTCATCG 
GTGACAGCCG TGCGCGAAGT GCTCGAAGAA GCCGGCGTGG TTGGCGATCT GGGTCGTTGT 
CTCGGTGTAT TCGAGAACAA TGACCACATG CATCGCACCG AGGTGTTCGT GATGAACGTG 
ACTCAGGAAC TGGACGAGTG GGAGGATTCG CGGAGCATCG GTCGCAAGCG CCAGTGGTTC 
ACCATCGATG ATGCACTCTC GCAGCTGGCG CTGCATAAGC CGACGCAGCA ACACTATCTG 
ATGCAGCTGC AGCACTCGAA GACGCTGGAC AACACGAATC GCGTGGTGAA CGCCACGCAT 
CCGCCCAAGT TGACCAATGC CGCCACCCCA GCCGCATCTC CCACTACGGC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_729639.1
CDS	1147..1680
Translation	MVKEKPNSTRIYDKDGFRRRAACICVKSENEAEVLLVTSSRRPELWIVPGGGVEPEEESSVTAVREVLEEAGVVGDLGRCLGVFENNDHMHRTEVFVMNVTQELDEWEDSRSIGRKRQWFTIDDALSQLALHKPTQQHYLMQLQHSKTLDNTNRVVNATHPPKLTNAATPAASPTTA

Target ORF information:

RefSeq Version	NM_168425.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Aps, transcript variant B (Aps), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_168425.3

ORF Insert Sequence:

ATGGTCAAGG AGAAGCCCAA CTCGACTCGC ATCTACGACA AGGATGGATT TAGGCGCCGG 
GCTGCTTGTA TTTGCGTGAA ATCGGAGAAT GAGGCGGAGG TACTCTTGGT AACCTCATCT 
CGTCGCCCGG AGTTGTGGAT CGTTCCAGGA GGCGGCGTTG AACCAGAAGA GGAGTCATCG 
GTGACAGCCG TGCGCGAAGT GCTCGAAGAA GCCGGCGTGG TTGGCGATCT GGGTCGTTGT 
CTCGGTGTAT TCGAGAACAA TGACCACATG CATCGCACCG AGGTGTTCGT GATGAACGTG 
ACTCAGGAAC TGGACGAGTG GGAGGATTCG CGGAGCATCG GTCGCAAGCG CCAGTGGTTC 
ACCATCGATG ATGCACTCTC GCAGCTGGCG CTGCATAAGC CGACGCAGCA ACACTATCTG 
ATGCAGCTGC AGCACTCGAA GACGCTGGAC AACACGAATC GCGTGGTGAA CGCCACGCAT 
CCGCCCAAGT TGACCAATGC CGCCACCCCA GCCGCATCTC CCACTACGGC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aps ( NM_168426.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_729640.1 Drosophila melanogaster Aps, transcript variant C (Aps), mRNA.

Price & Availability↑

CloneID	OFa18188
Clone ID Related Accession (Same CDS sequence)	NM_168425.3 , NM_168426.3 , NM_140164.4
Accession Version	NM_168426.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 534bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Aps, isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jan 16, 2013 this sequence version replaced NM_168426.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGTCAAGG AGAAGCCCAA CTCGACTCGC ATCTACGACA AGGATGGATT TAGGCGCCGG 
GCTGCTTGTA TTTGCGTGAA ATCGGAGAAT GAGGCGGAGG TACTCTTGGT AACCTCATCT 
CGTCGCCCGG AGTTGTGGAT CGTTCCAGGA GGCGGCGTTG AACCAGAAGA GGAGTCATCG 
GTGACAGCCG TGCGCGAAGT GCTCGAAGAA GCCGGCGTGG TTGGCGATCT GGGTCGTTGT 
CTCGGTGTAT TCGAGAACAA TGACCACATG CATCGCACCG AGGTGTTCGT GATGAACGTG 
ACTCAGGAAC TGGACGAGTG GGAGGATTCG CGGAGCATCG GTCGCAAGCG CCAGTGGTTC 
ACCATCGATG ATGCACTCTC GCAGCTGGCG CTGCATAAGC CGACGCAGCA ACACTATCTG 
ATGCAGCTGC AGCACTCGAA GACGCTGGAC AACACGAATC GCGTGGTGAA CGCCACGCAT 
CCGCCCAAGT TGACCAATGC CGCCACCCCA GCCGCATCTC CCACTACGGC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_729640.1
CDS	856..1389
Translation	MVKEKPNSTRIYDKDGFRRRAACICVKSENEAEVLLVTSSRRPELWIVPGGGVEPEEESSVTAVREVLEEAGVVGDLGRCLGVFENNDHMHRTEVFVMNVTQELDEWEDSRSIGRKRQWFTIDDALSQLALHKPTQQHYLMQLQHSKTLDNTNRVVNATHPPKLTNAATPAASPTTA

Target ORF information:

RefSeq Version	NM_168426.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Aps, transcript variant C (Aps), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_168426.3

ORF Insert Sequence:

ATGGTCAAGG AGAAGCCCAA CTCGACTCGC ATCTACGACA AGGATGGATT TAGGCGCCGG 
GCTGCTTGTA TTTGCGTGAA ATCGGAGAAT GAGGCGGAGG TACTCTTGGT AACCTCATCT 
CGTCGCCCGG AGTTGTGGAT CGTTCCAGGA GGCGGCGTTG AACCAGAAGA GGAGTCATCG 
GTGACAGCCG TGCGCGAAGT GCTCGAAGAA GCCGGCGTGG TTGGCGATCT GGGTCGTTGT 
CTCGGTGTAT TCGAGAACAA TGACCACATG CATCGCACCG AGGTGTTCGT GATGAACGTG 
ACTCAGGAAC TGGACGAGTG GGAGGATTCG CGGAGCATCG GTCGCAAGCG CCAGTGGTTC 
ACCATCGATG ATGCACTCTC GCAGCTGGCG CTGCATAAGC CGACGCAGCA ACACTATCTG 
ATGCAGCTGC AGCACTCGAA GACGCTGGAC AACACGAATC GCGTGGTGAA CGCCACGCAT 
CCGCCCAAGT TGACCAATGC CGCCACCCCA GCCGCATCTC CCACTACGGC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aps ( NM_140164.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_648421.1 Drosophila melanogaster Aps, transcript variant A (Aps), mRNA.

Price & Availability↑

CloneID	OFa18188
Clone ID Related Accession (Same CDS sequence)	NM_168425.3 , NM_168426.3 , NM_140164.4
Accession Version	NM_140164.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 534bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Aps, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jul 15, 2014 this sequence version replaced NM_140164.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGTCAAGG AGAAGCCCAA CTCGACTCGC ATCTACGACA AGGATGGATT TAGGCGCCGG 
GCTGCTTGTA TTTGCGTGAA ATCGGAGAAT GAGGCGGAGG TACTCTTGGT AACCTCATCT 
CGTCGCCCGG AGTTGTGGAT CGTTCCAGGA GGCGGCGTTG AACCAGAAGA GGAGTCATCG 
GTGACAGCCG TGCGCGAAGT GCTCGAAGAA GCCGGCGTGG TTGGCGATCT GGGTCGTTGT 
CTCGGTGTAT TCGAGAACAA TGACCACATG CATCGCACCG AGGTGTTCGT GATGAACGTG 
ACTCAGGAAC TGGACGAGTG GGAGGATTCG CGGAGCATCG GTCGCAAGCG CCAGTGGTTC 
ACCATCGATG ATGCACTCTC GCAGCTGGCG CTGCATAAGC CGACGCAGCA ACACTATCTG 
ATGCAGCTGC AGCACTCGAA GACGCTGGAC AACACGAATC GCGTGGTGAA CGCCACGCAT 
CCGCCCAAGT TGACCAATGC CGCCACCCCA GCCGCATCTC CCACTACGGC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_648421.1
CDS	677..1210
Translation	MVKEKPNSTRIYDKDGFRRRAACICVKSENEAEVLLVTSSRRPELWIVPGGGVEPEEESSVTAVREVLEEAGVVGDLGRCLGVFENNDHMHRTEVFVMNVTQELDEWEDSRSIGRKRQWFTIDDALSQLALHKPTQQHYLMQLQHSKTLDNTNRVVNATHPPKLTNAATPAASPTTA

Target ORF information:

RefSeq Version	NM_140164.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Aps, transcript variant A (Aps), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_140164.4

ORF Insert Sequence:

ATGGTCAAGG AGAAGCCCAA CTCGACTCGC ATCTACGACA AGGATGGATT TAGGCGCCGG 
GCTGCTTGTA TTTGCGTGAA ATCGGAGAAT GAGGCGGAGG TACTCTTGGT AACCTCATCT 
CGTCGCCCGG AGTTGTGGAT CGTTCCAGGA GGCGGCGTTG AACCAGAAGA GGAGTCATCG 
GTGACAGCCG TGCGCGAAGT GCTCGAAGAA GCCGGCGTGG TTGGCGATCT GGGTCGTTGT 
CTCGGTGTAT TCGAGAACAA TGACCACATG CATCGCACCG AGGTGTTCGT GATGAACGTG 
ACTCAGGAAC TGGACGAGTG GGAGGATTCG CGGAGCATCG GTCGCAAGCG CCAGTGGTTC 
ACCATCGATG ATGCACTCTC GCAGCTGGCG CTGCATAAGC CGACGCAGCA ACACTATCTG 
ATGCAGCTGC AGCACTCGAA GACGCTGGAC AACACGAATC GCGTGGTGAA CGCCACGCAT 
CCGCCCAAGT TGACCAATGC CGCCACCCCA GCCGCATCTC CCACTACGGC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Aps cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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