Rac2 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rac2
Entrez Gene ID	38831
Full Name	CG8556 gene product from transcript CG8556-RB
Synonyms	CG8556,D-Rac 2,D-Rac2,DRac2,DRacB,DmRAC2,Dmel\CG8556,Drac1b,Drac2,P48554,Rac,Rac GTPase,Rac-2,Rac1,Rac1b,RacB,rac2
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3L Map Location: 66A1-66A1

mRNA and Protein(s)

mRNA	Protein	Name
NM_139864.3	NP_648121.1	Rac2, isoform A
NM_001274588.2	NP_001261517.1	Rac2, isoform B

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	RAC1	NP_001003274.1
Bos taurus (cattle)	RAC1	NP_776588.1
Danio rerio (zebrafish)	rac1a	NP_956065.1
Drosophila melanogaster (fruit fly)	Rac2	NP_001261517.1
	LOC717755	XP_001109586.2
Mus musculus (house mouse)	Rac1	NP_033033.1
Drosophila melanogaster (fruit fly)	Rac1	NP_476950.1
Arabidopsis thaliana (thale cress)	ROP1	NP_190698.1
Arabidopsis thaliana (thale cress)	RAC6	NP_195320.1
Xenopus tropicalis (tropical clawed frog)	rac1	NP_001004840.1
Rattus norvegicus (Norway rat)	Rac1	NP_599193.1
Gallus gallus (chicken)	RAC1	NP_990348.1
Pan troglodytes (chimpanzee)	RAC1	NP_001233310.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005445	XP_315449.4
Homo sapiens (human)	RAC1	NP_061485.1
Arabidopsis thaliana (thale cress)	ARAC1	NP_179371.1
Oryza sativa (rice)	Os02g0120800	NP_001045712.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Rac2 has a central role in regulating the Drosophila homeostatic system.
Title: The Drosophila small GTPase Rac2 is required for normal feeding and mating behaviour.

Zir is necessary to activate the Rho-family GTPases Rac2 and Cdc42 during the Drosophila cellular immune response.
Title: The RhoGEF Zizimin-related acts in the Drosophila cellular immune response via the Rho GTPases Rac2 and Cdc42.

Findings demonstrate that light-induced translocation of Arr2 occurs through a noncanonical rhodopsin/Rac2 pathway, which is distinct from the classical phototransduction cascade.
Title: Light-induced translocation of Drosophila visual Arrestin2 depends on Rac2.

Rac2 is the main host factor whose function is inhibited by the GAP domain of the ExoS toxin
Title: Rac2 is a major actor of Drosophila resistance to Pseudomonas aeruginosa acting in phagocytic cells.

Rho GTPases may have partially overlapping functions during planar cell polarity generation
Title: Analysis of the role of the Rac/Cdc42 GTPases during planar cell polarity generation in Drosophila.

The following Rac2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rac2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa17801	NM_139864.3 Latest version!	Drosophila melanogaster Rac2, transcript variant A (Rac2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OFa17801	NM_001274588.2 Latest version!	Drosophila melanogaster Rac2, transcript variant B (Rac2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rac2 ( NM_139864.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_648121.1 Drosophila melanogaster Rac2, transcript variant A (Rac2), mRNA.

Price & Availability↑

CloneID	OFa17801
Clone ID Related Accession (Same CDS sequence)	NM_139864.3 , NM_001274588.2
Accession Version	NM_139864.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Rac2, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jan 16, 2013 this sequence version replaced NM_139864.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGCAGGCCA TCAAGTGTGT GGTTGTGGGC GACGGAGCGG TGGGAAAGAC CTGTCTGCTG 
ATCAGCTATA CGACCAACGC CTTCCCCGGC GAGTACATAC CCACGGTGTT CGACAACTAT 
TCGGCGAATG TGATGGTGGA TGCCAAGCCC ATCAATCTGG GCCTCTGGGA TACGGCTGGA 
CAGGAGGACT ACGATCGCCT GAGGCCGCTA TCCTATCCGC AAACGGATGT CTTTCTCATC 
TGTTTCTCAC TGGTGAATCC GGCATCGTTT GAGAATGTGC GAGCCAAATG GTTTCCCGAG 
GTGCGTCATC ATTGCCCGAG TGTGCCGATA ATCCTGGTCG GCACCAAACT GGATCTGCGC 
GACGATAAGC AGACGATCGA GAAGCTGAAG GACAAGAAGC TAACACCGAT CACCTATCCC 
CAAGGACTGG CGATGGCCAA GGAAATAGCT GCGGTCAAGT ATCTGGAGTG CTCGGCCCTG 
ACCCAAAAGG GTCTGAAGAC GGTCTTCGAC GAGGCCATAC GATCCGTGCT ATGTCCTGTC 
GTTCGAGGAC CCAAGCGGCA CAAGTGCGCC CTGCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_648121.1
CDS	681..1259
Translation	MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVGTKLDLRDDKQTIEKLKDKKLTPITYPQGLAMAKEIAAVKYLECSALTQKGLKTVFDEAIRSVLCPVVRGPKRHKCALL

Target ORF information:

RefSeq Version	NM_139864.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Rac2, transcript variant A (Rac2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139864.3

ORF Insert Sequence:

ATGCAGGCCA TCAAGTGTGT GGTTGTGGGC GACGGAGCGG TGGGAAAGAC CTGTCTGCTG 
ATCAGCTATA CGACCAACGC CTTCCCCGGC GAGTACATAC CCACGGTGTT CGACAACTAT 
TCGGCGAATG TGATGGTGGA TGCCAAGCCC ATCAATCTGG GCCTCTGGGA TACGGCTGGA 
CAGGAGGACT ACGATCGCCT GAGGCCGCTA TCCTATCCGC AAACGGATGT CTTTCTCATC 
TGTTTCTCAC TGGTGAATCC GGCATCGTTT GAGAATGTGC GAGCCAAATG GTTTCCCGAG 
GTGCGTCATC ATTGCCCGAG TGTGCCGATA ATCCTGGTCG GCACCAAACT GGATCTGCGC 
GACGATAAGC AGACGATCGA GAAGCTGAAG GACAAGAAGC TAACACCGAT CACCTATCCC 
CAAGGACTGG CGATGGCCAA GGAAATAGCT GCGGTCAAGT ATCTGGAGTG CTCGGCCCTG 
ACCCAAAAGG GTCTGAAGAC GGTCTTCGAC GAGGCCATAC GATCCGTGCT ATGTCCTGTC 
GTTCGAGGAC CCAAGCGGCA CAAGTGCGCC CTGCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rac2 ( NM_001274588.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001261517.1 Drosophila melanogaster Rac2, transcript variant B (Rac2), mRNA.

Price & Availability↑

CloneID	OFa17801
Clone ID Related Accession (Same CDS sequence)	NM_139864.3 , NM_001274588.2
Accession Version	NM_001274588.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Rac2, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Oct 19, 2015 this sequence version replaced NM_001274588.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGCAGGCCA TCAAGTGTGT GGTTGTGGGC GACGGAGCGG TGGGAAAGAC CTGTCTGCTG 
ATCAGCTATA CGACCAACGC CTTCCCCGGC GAGTACATAC CCACGGTGTT CGACAACTAT 
TCGGCGAATG TGATGGTGGA TGCCAAGCCC ATCAATCTGG GCCTCTGGGA TACGGCTGGA 
CAGGAGGACT ACGATCGCCT GAGGCCGCTA TCCTATCCGC AAACGGATGT CTTTCTCATC 
TGTTTCTCAC TGGTGAATCC GGCATCGTTT GAGAATGTGC GAGCCAAATG GTTTCCCGAG 
GTGCGTCATC ATTGCCCGAG TGTGCCGATA ATCCTGGTCG GCACCAAACT GGATCTGCGC 
GACGATAAGC AGACGATCGA GAAGCTGAAG GACAAGAAGC TAACACCGAT CACCTATCCC 
CAAGGACTGG CGATGGCCAA GGAAATAGCT GCGGTCAAGT ATCTGGAGTG CTCGGCCCTG 
ACCCAAAAGG GTCTGAAGAC GGTCTTCGAC GAGGCCATAC GATCCGTGCT ATGTCCTGTC 
GTTCGAGGAC CCAAGCGGCA CAAGTGCGCC CTGCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001261517.1
CDS	681..1259
Translation	MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVGTKLDLRDDKQTIEKLKDKKLTPITYPQGLAMAKEIAAVKYLECSALTQKGLKTVFDEAIRSVLCPVVRGPKRHKCALL

Target ORF information:

RefSeq Version	NM_001274588.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Rac2, transcript variant B (Rac2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001274588.2

ORF Insert Sequence:

ATGCAGGCCA TCAAGTGTGT GGTTGTGGGC GACGGAGCGG TGGGAAAGAC CTGTCTGCTG 
ATCAGCTATA CGACCAACGC CTTCCCCGGC GAGTACATAC CCACGGTGTT CGACAACTAT 
TCGGCGAATG TGATGGTGGA TGCCAAGCCC ATCAATCTGG GCCTCTGGGA TACGGCTGGA 
CAGGAGGACT ACGATCGCCT GAGGCCGCTA TCCTATCCGC AAACGGATGT CTTTCTCATC 
TGTTTCTCAC TGGTGAATCC GGCATCGTTT GAGAATGTGC GAGCCAAATG GTTTCCCGAG 
GTGCGTCATC ATTGCCCGAG TGTGCCGATA ATCCTGGTCG GCACCAAACT GGATCTGCGC 
GACGATAAGC AGACGATCGA GAAGCTGAAG GACAAGAAGC TAACACCGAT CACCTATCCC 
CAAGGACTGG CGATGGCCAA GGAAATAGCT GCGGTCAAGT ATCTGGAGTG CTCGGCCCTG 
ACCCAAAAGG GTCTGAAGAC GGTCTTCGAC GAGGCCATAC GATCCGTGCT ATGTCCTGTC 
GTTCGAGGAC CCAAGCGGCA CAAGTGCGCC CTGCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Rac2 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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