Rrp4 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rrp4
Entrez Gene ID	37731
Full Name	CG3931 gene product from transcript CG3931-RA
Synonyms	CG3931,Dmel\CG3931,RRP4,dRrp4,rrp4
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2R Map Location: 59E3-59E3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001299842.1	NP_001286771.1	Rrp4, isoform B
NM_137963.2	NP_611807.1	Rrp4, isoform A

Pathways from BioSystems

Homologies

Homo sapiens (human)	EXOSC2	NP_055100.2
Canis lupus familiaris (dog)	EXOSC2	XP_005625290.1
Caenorhabditis elegans (roundworm)	exos-2	NP_500978.1
Schizosaccharomyces pombe (fission yeast)	SPAC2F7.14c	NP_592984.1
Neurospora crassa	NCU04009	XP_957624.2
Pan troglodytes (chimpanzee)	EXOSC2	XP_001166030.1
Gallus gallus (chicken)	EXOSC2	NP_001012816.2
Danio rerio (zebrafish)	exosc2	NP_001017572.2
Magnaporthe oryzae (rice blast fungus)	MGG_08100	XP_003715055.1
Oryza sativa (rice)	Os04g0520000	NP_001053332.1
	EXOSC2	XP_001106567.1
Xenopus tropicalis (tropical clawed frog)	exosc2	NP_001025658.1
Rattus norvegicus (Norway rat)	Exosc2	NP_001102422.1
Drosophila melanogaster (fruit fly)	Rrp4	NP_611807.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011211	XP_309432.3
Arabidopsis thaliana (thale cress)	RRP4	NP_171835.1
Bos taurus (cattle)	EXOSC2	NP_001040026.1
Mus musculus (house mouse)	Exosc2	NP_659135.1
Saccharomyces cerevisiae (baker's yeast)	RRP4	NP_011936.1
Kluyveromyces lactis	KLLA0E12739g	XP_454524.1
Eremothecium gossypii	AGOS_AAL034C	NP_982508.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that depletion of Hrp59 by RNA interference reduces the levels of Rrp4 at transcription sites, which suggests that Hrp59 is needed for the exosome to stably interact with nascent pre-mRNPs.
Title: The exosome associates cotranscriptionally with the nascent pre-mRNP through interactions with heterogeneous nuclear ribonucleoproteins.

The following Rrp4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rrp4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa11055	NM_137963.2 Latest version!	Drosophila melanogaster Rrp4, transcript variant A (Rrp4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OFa11055	NM_001299842.1 Latest version!	Drosophila melanogaster Rrp4, transcript variant B (Rrp4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rrp4 ( NM_001299842.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001286771.1 Drosophila melanogaster Rrp4, transcript variant B (Rrp4), mRNA.

Price & Availability↑

CloneID	OFa11055
Clone ID Related Accession (Same CDS sequence)	NM_001299842.1 , NM_137963.2
Accession Version	NM_001299842.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 897bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Rrp4, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTCCACCA ACGCGGCGAT AGATCTGGCC CTGGACCGGG TGGACTGGCG CGACCTGGCC 
GCGCAGACGG AGGAACAGCC GAGGGTGTAT ACGCCGGGGG AAGTGCTGAT GCCGGAGGCG 
GGATTCATGC GCGGCCACGG AACCTTCGTC GAGGACGAGA ACATCAAGTC CTCGGTGGCC 
GGGGTGATCC AGAAGGTCAA CAAGCTGATC TCGGTGCGCC CGCTTAAGAG TCGCTATGTG 
GGCGAGATCG GGGACGTGGT GGTGGCCCGC GTCAGCGAGG TGCAACAGAA GCGCTGGCGA 
GTGGACACCA ATTCCCGGCT CGACTCCATC CTACTGCTCT CCTCGGTGAA TCTGCCAGGC 
GGAGAACTAC GACGGAGATC GGCGGAGGAC GAGCAGATGA TGCGACGATA CTTGGACGAG 
GGCGATCTCA TCTCTGCCGA GGTCCAGAAC ATCTTTGAGG AGGGCTCCCT TTCGCTGTAC 
ACGCGCAGTT TGAAGTATGG AAAACTATCG CAGGGCATCC TGGTCAAGGT GTTCCCCGCT 
CTCGTCAAGC GCCGCAAGAT GCACTTCCAC AACCTGCCCT GCGGCGCCTC CGTGATCCTG 
GGCAACAATG GCTACATCTG GATATCGCCG ACCAAGGGCC AGGAGGAGGA AGGCGGCGAG 
GGAGGATTCG CTCAGAACCT GAACGAGCAT GTGCCGCGCG CGGATCGGGA GGTGATCGCC 
CGGCTGAGGA ACTCCATCCT CGCGCTGGCC AAGTGCAAGC TGATGATTTA CGACACCAGC 
ATCCAGTACG CCTACGAGGA GTCCCTGCGC TACGAGGCCC ACGAGCTGCT CCAGCAGAAC 
GCCATCTACG ACATCGGCCA GCAGACGCAG GCTCGTCTGA GGGACGCGGA CGAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001286771.1
CDS	80..976
Translation	MSTNAAIDLALDRVDWRDLAAQTEEQPRVYTPGEVLMPEAGFMRGHGTFVEDENIKSSVAGVIQKVNKLISVRPLKSRYVGEIGDVVVARVSEVQQKRWRVDTNSRLDSILLLSSVNLPGGELRRRSAEDEQMMRRYLDEGDLISAEVQNIFEEGSLSLYTRSLKYGKLSQGILVKVFPALVKRRKMHFHNLPCGASVILGNNGYIWISPTKGQEEEGGEGGFAQNLNEHVPRADREVIARLRNSILALAKCKLMIYDTSIQYAYEESLRYEAHELLQQNAIYDIGQQTQARLRDADE

Target ORF information:

RefSeq Version	NM_001299842.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Rrp4, transcript variant B (Rrp4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001299842.1

ORF Insert Sequence:

ATGTCCACCA ACGCGGCGAT AGATCTGGCC CTGGACCGGG TGGACTGGCG CGACCTGGCC 
GCGCAGACGG AGGAACAGCC GAGGGTGTAT ACGCCGGGGG AAGTGCTGAT GCCGGAGGCG 
GGATTCATGC GCGGCCACGG AACCTTCGTC GAGGACGAGA ACATCAAGTC CTCGGTGGCC 
GGGGTGATCC AGAAGGTCAA CAAGCTGATC TCGGTGCGCC CGCTTAAGAG TCGCTATGTG 
GGCGAGATCG GGGACGTGGT GGTGGCCCGC GTCAGCGAGG TGCAACAGAA GCGCTGGCGA 
GTGGACACCA ATTCCCGGCT CGACTCCATC CTACTGCTCT CCTCGGTGAA TCTGCCAGGC 
GGAGAACTAC GACGGAGATC GGCGGAGGAC GAGCAGATGA TGCGACGATA CTTGGACGAG 
GGCGATCTCA TCTCTGCCGA GGTCCAGAAC ATCTTTGAGG AGGGCTCCCT TTCGCTGTAC 
ACGCGCAGTT TGAAGTATGG AAAACTATCG CAGGGCATCC TGGTCAAGGT GTTCCCCGCT 
CTCGTCAAGC GCCGCAAGAT GCACTTCCAC AACCTGCCCT GCGGCGCCTC CGTGATCCTG 
GGCAACAATG GCTACATCTG GATATCGCCG ACCAAGGGCC AGGAGGAGGA AGGCGGCGAG 
GGAGGATTCG CTCAGAACCT GAACGAGCAT GTGCCGCGCG CGGATCGGGA GGTGATCGCC 
CGGCTGAGGA ACTCCATCCT CGCGCTGGCC AAGTGCAAGC TGATGATTTA CGACACCAGC 
ATCCAGTACG CCTACGAGGA GTCCCTGCGC TACGAGGCCC ACGAGCTGCT CCAGCAGAAC 
GCCATCTACG ACATCGGCCA GCAGACGCAG GCTCGTCTGA GGGACGCGGA CGAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rrp4 ( NM_137963.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_611807.1 Drosophila melanogaster Rrp4, transcript variant A (Rrp4), mRNA.

Price & Availability↑

CloneID	OFa11055
Clone ID Related Accession (Same CDS sequence)	NM_001299842.1 , NM_137963.2
Accession Version	NM_137963.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 897bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Rrp4, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jul 15, 2014 this sequence version replaced NM_137963.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTCCACCA ACGCGGCGAT AGATCTGGCC CTGGACCGGG TGGACTGGCG CGACCTGGCC 
GCGCAGACGG AGGAACAGCC GAGGGTGTAT ACGCCGGGGG AAGTGCTGAT GCCGGAGGCG 
GGATTCATGC GCGGCCACGG AACCTTCGTC GAGGACGAGA ACATCAAGTC CTCGGTGGCC 
GGGGTGATCC AGAAGGTCAA CAAGCTGATC TCGGTGCGCC CGCTTAAGAG TCGCTATGTG 
GGCGAGATCG GGGACGTGGT GGTGGCCCGC GTCAGCGAGG TGCAACAGAA GCGCTGGCGA 
GTGGACACCA ATTCCCGGCT CGACTCCATC CTACTGCTCT CCTCGGTGAA TCTGCCAGGC 
GGAGAACTAC GACGGAGATC GGCGGAGGAC GAGCAGATGA TGCGACGATA CTTGGACGAG 
GGCGATCTCA TCTCTGCCGA GGTCCAGAAC ATCTTTGAGG AGGGCTCCCT TTCGCTGTAC 
ACGCGCAGTT TGAAGTATGG AAAACTATCG CAGGGCATCC TGGTCAAGGT GTTCCCCGCT 
CTCGTCAAGC GCCGCAAGAT GCACTTCCAC AACCTGCCCT GCGGCGCCTC CGTGATCCTG 
GGCAACAATG GCTACATCTG GATATCGCCG ACCAAGGGCC AGGAGGAGGA AGGCGGCGAG 
GGAGGATTCG CTCAGAACCT GAACGAGCAT GTGCCGCGCG CGGATCGGGA GGTGATCGCC 
CGGCTGAGGA ACTCCATCCT CGCGCTGGCC AAGTGCAAGC TGATGATTTA CGACACCAGC 
ATCCAGTACG CCTACGAGGA GTCCCTGCGC TACGAGGCCC ACGAGCTGCT CCAGCAGAAC 
GCCATCTACG ACATCGGCCA GCAGACGCAG GCTCGTCTGA GGGACGCGGA CGAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_611807.1
CDS	80..976
Translation	MSTNAAIDLALDRVDWRDLAAQTEEQPRVYTPGEVLMPEAGFMRGHGTFVEDENIKSSVAGVIQKVNKLISVRPLKSRYVGEIGDVVVARVSEVQQKRWRVDTNSRLDSILLLSSVNLPGGELRRRSAEDEQMMRRYLDEGDLISAEVQNIFEEGSLSLYTRSLKYGKLSQGILVKVFPALVKRRKMHFHNLPCGASVILGNNGYIWISPTKGQEEEGGEGGFAQNLNEHVPRADREVIARLRNSILALAKCKLMIYDTSIQYAYEESLRYEAHELLQQNAIYDIGQQTQARLRDADE

Target ORF information:

RefSeq Version	NM_137963.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Rrp4, transcript variant A (Rrp4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_137963.2

ORF Insert Sequence:

ATGTCCACCA ACGCGGCGAT AGATCTGGCC CTGGACCGGG TGGACTGGCG CGACCTGGCC 
GCGCAGACGG AGGAACAGCC GAGGGTGTAT ACGCCGGGGG AAGTGCTGAT GCCGGAGGCG 
GGATTCATGC GCGGCCACGG AACCTTCGTC GAGGACGAGA ACATCAAGTC CTCGGTGGCC 
GGGGTGATCC AGAAGGTCAA CAAGCTGATC TCGGTGCGCC CGCTTAAGAG TCGCTATGTG 
GGCGAGATCG GGGACGTGGT GGTGGCCCGC GTCAGCGAGG TGCAACAGAA GCGCTGGCGA 
GTGGACACCA ATTCCCGGCT CGACTCCATC CTACTGCTCT CCTCGGTGAA TCTGCCAGGC 
GGAGAACTAC GACGGAGATC GGCGGAGGAC GAGCAGATGA TGCGACGATA CTTGGACGAG 
GGCGATCTCA TCTCTGCCGA GGTCCAGAAC ATCTTTGAGG AGGGCTCCCT TTCGCTGTAC 
ACGCGCAGTT TGAAGTATGG AAAACTATCG CAGGGCATCC TGGTCAAGGT GTTCCCCGCT 
CTCGTCAAGC GCCGCAAGAT GCACTTCCAC AACCTGCCCT GCGGCGCCTC CGTGATCCTG 
GGCAACAATG GCTACATCTG GATATCGCCG ACCAAGGGCC AGGAGGAGGA AGGCGGCGAG 
GGAGGATTCG CTCAGAACCT GAACGAGCAT GTGCCGCGCG CGGATCGGGA GGTGATCGCC 
CGGCTGAGGA ACTCCATCCT CGCGCTGGCC AAGTGCAAGC TGATGATTTA CGACACCAGC 
ATCCAGTACG CCTACGAGGA GTCCCTGCGC TACGAGGCCC ACGAGCTGCT CCAGCAGAAC 
GCCATCTACG ACATCGGCCA GCAGACGCAG GCTCGTCTGA GGGACGCGGA CGAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Rrp4 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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