Sod2 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sod2
Entrez Gene ID	36878
Full Name	Superoxide dismutase 2 (Mn)
Synonyms	CG8905,Dmel\CG8905,Mito SOD,Mn SOD,Mn-SOD,Mn-SOD2,MnSOD,MnSODII,Mn[2+]SOD,SOD,SOD-2,SOD2,Sod-2,dSOD2,dSod2,mitSOD2,mnSOD,sod2
General protein information	Preferred Names Superoxide dismutase 2 (Mn) Names CG8905 gene product from transcript CG8905-RB CG8905-PA CG8905-PB Mn superoxide dismutase Mn-superoxide dismutase MnSOD Sod2-PA Sod2-PB manganese superoxide dismutase manganese-SOD mitochodnrial SOD mitochondrial Mn-superoxide dismutase 2 mitochondrial MnSOD mitochondrial superoxide dismutase 2 superoxide dismutase superoxide dismutase 2 superoxide dismutase 2 (Mn) superoxide dismutase-2 superoxide dismutatase 2
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2R Map Location: 53D8-53D8

mRNA and Protein(s)

mRNA	Protein	Name
NM_001299574.1	NP_001286503.1	superoxide dismutase 2 (Mn), isoform B
NM_057577.4	NP_476925.1	superoxide dismutase 2 (Mn), isoform A

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SOD2	XP_533463.3
Anopheles gambiae (African malaria mosquito)	MNSOD1	XP_314490.4
Caenorhabditis elegans (roundworm)	sod-3	NP_510764.1
Eremothecium gossypii	AGOS_ADR160W	NP_984257.2
Magnaporthe oryzae (rice blast fungus)	MGG_00212	XP_003718898.1
Bos taurus (cattle)	SOD2	NP_963285.2
Gallus gallus (chicken)	SOD2	NP_989542.1
Caenorhabditis elegans (roundworm)	sod-2	NP_492290.1
Neurospora crassa	NCU09560	XP_959485.1
Oryza sativa (rice)	Os05g0323900	NP_001055195.1
Homo sapiens (human)	SOD2	NP_000627.2
Danio rerio (zebrafish)	sod2	NP_956270.1
Drosophila melanogaster (fruit fly)	Sod2	NP_476925.1
Saccharomyces cerevisiae (baker's yeast)	SOD2	NP_011872.1
Kluyveromyces lactis	KLLA0E03609g	XP_454107.1
Xenopus tropicalis (tropical clawed frog)	sod2	NP_001005694.1
Pan troglodytes (chimpanzee)	SOD2	NP_001009022.1
	SOD2	NP_001027977.1
Mus musculus (house mouse)	Sod2	NP_038699.2
Rattus norvegicus (Norway rat)	Sod2	NP_058747.1
Schizosaccharomyces pombe (fission yeast)	SPAC1486.01	NP_594089.1
Arabidopsis thaliana (thale cress)	MSD1	NP_187703.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Depletion of superoxide dismutases promotes muscular and neuronal ROS accumulation which may have a significant effect on age-dependent impairment of the Drosophila adults.
Title: A correlation of reactive oxygen species accumulation by depletion of superoxide dismutases with age-dependent impairment in the nervous system and muscles of Drosophila adults.

The functional SOD1 and SOD2 genes knockout and their overexpression in neurons and glial tissue increase the sensitivity of Drosophila melanogaster to oxidative stress conditions.
Title: [Influence of tissue-specific superoxide dismutase genes expression in brain cells on Drosophila melanogaster sensitivity to oxidative stress and viability].

Paraquat exposure, but not Sod2 knockdown, resulted in increased carbonylated protein relative abundance.
Title: Paraquat exposure and Sod2 knockdown have dissimilar impacts on the Drosophila melanogaster carbonylated protein proteome.

ocytes lacking maternal SOD2 protein develop into adults just like normal SOD2-containing oocytes suggesting that maternal SOD2-mediated protection against mitochondrial ROS is not essential for oocyte viability
Title: SOD2, the principal scavenger of mitochondrial superoxide, is dispensable for embryogenesis and imaginal tissue development but essential for adult survival.

Muscles appear to be more sensitive to superoxide attack relative to the neurons and such overt phenotypes observed in SOD2-deficient animals can be directly attributed to the muscle.
Title: Mitochondrial superoxide radicals differentially affect muscle activity and neural function.

The following Sod2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sod2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa10268	NM_001299574.1 Latest version!	Drosophila melanogaster superoxide dismutase 2 (Mn), transcript variant B (Sod2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OFa10268	NM_057577.4 Latest version!	Drosophila melanogaster superoxide dismutase 2 (Mn), transcript variant A (Sod2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sod2 ( NM_001299574.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001286503.1 Drosophila melanogaster superoxide dismutase 2 (Mn), transcript variant B (Sod2), mRNA.

Price & Availability↑

CloneID	OFa10268
Clone ID Related Accession (Same CDS sequence)	NM_001299574.1 , NM_057577.4
Accession Version	NM_001299574.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	superoxide dismutase 2 (Mn), isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTTCGTGG CCCGTAAAAT TTCGCAAACT GCAAGCCTGG CGGTGCGTGG CAAGCACACC 
CTACCGAAGC TGCCCTACGA CTATGCCGCC CTGGAGCCTA TCATCTGCCG GGAGATCATG 
GAGCTGCATC ACCAGAAGCA CCACCAGACC TACGTCAACA ATCTAAATGC CGCCGAGGAG 
CAGCTGGAGG AGGCCAAGTC GAAGAGCGAC ACCACCAAGC TGATTCAGCT GGCTCCTGCC 
CTGCGTTTCA ATGGCGGTGG CCACATCAAC CACACCATCT TCTGGCAGAA CCTCTCGCCC 
AACAAGACCC AGCCCAGCGA TGATCTGAAG AAGGCCATCG AGTCGCAGTG GAAGAGCCTC 
GAGGAGTTCA AAAAGGAGCT GACCACGCTG ACCGTGGCGG TCCAGGGCTC CGGCTGGGGC 
TGGCTGGGCT TCAACAAGAA GTCGGGCAAA CTGCAACTGG CCGCCCTGCC CAACCAGGAT 
CCCCTGGAGG CCTCCACCGG CCTGATCCCG CTCTTCGGCA TCGATGTCTG GGAGCACGCC 
TACTATCTGC AGTACAAGAA CGTGCGTCCC TCCTACGTGG AGGCCATCTG GGACATCGCC 
AACTGGGATG ACATCTCGTG CCGCTTCCAG GAGGCCAAGA AGCTCGGTTG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001286503.1
CDS	127..780
Translation	MFVARKISQTASLAVRGKHTLPKLPYDYAALEPIICREIMELHHQKHHQTYVNNLNAAEEQLEEAKSKSDTTKLIQLAPALRFNGGGHINHTIFWQNLSPNKTQPSDDLKKAIESQWKSLEEFKKELTTLTVAVQGSGWGWLGFNKKSGKLQLAALPNQDPLEASTGLIPLFGIDVWEHAYYLQYKNVRPSYVEAIWDIANWDDISCRFQEAKKLGC

Target ORF information:

RefSeq Version	NM_001299574.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster superoxide dismutase 2 (Mn), transcript variant B (Sod2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001299574.1

ORF Insert Sequence:

ATGTTCGTGG CCCGTAAAAT TTCGCAAACT GCAAGCCTGG CGGTGCGTGG CAAGCACACC 
CTACCGAAGC TGCCCTACGA CTATGCCGCC CTGGAGCCTA TCATCTGCCG GGAGATCATG 
GAGCTGCATC ACCAGAAGCA CCACCAGACC TACGTCAACA ATCTAAATGC CGCCGAGGAG 
CAGCTGGAGG AGGCCAAGTC GAAGAGCGAC ACCACCAAGC TGATTCAGCT GGCTCCTGCC 
CTGCGTTTCA ATGGCGGTGG CCACATCAAC CACACCATCT TCTGGCAGAA CCTCTCGCCC 
AACAAGACCC AGCCCAGCGA TGATCTGAAG AAGGCCATCG AGTCGCAGTG GAAGAGCCTC 
GAGGAGTTCA AAAAGGAGCT GACCACGCTG ACCGTGGCGG TCCAGGGCTC CGGCTGGGGC 
TGGCTGGGCT TCAACAAGAA GTCGGGCAAA CTGCAACTGG CCGCCCTGCC CAACCAGGAT 
CCCCTGGAGG CCTCCACCGG CCTGATCCCG CTCTTCGGCA TCGATGTCTG GGAGCACGCC 
TACTATCTGC AGTACAAGAA CGTGCGTCCC TCCTACGTGG AGGCCATCTG GGACATCGCC 
AACTGGGATG ACATCTCGTG CCGCTTCCAG GAGGCCAAGA AGCTCGGTTG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sod2 ( NM_057577.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_476925.1 Drosophila melanogaster superoxide dismutase 2 (Mn), transcript variant A (Sod2), mRNA.

Price & Availability↑

CloneID	OFa10268
Clone ID Related Accession (Same CDS sequence)	NM_001299574.1 , NM_057577.4
Accession Version	NM_057577.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	superoxide dismutase 2 (Mn), isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jul 15, 2014 this sequence version replaced NM_057577.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTTCGTGG CCCGTAAAAT TTCGCAAACT GCAAGCCTGG CGGTGCGTGG CAAGCACACC 
CTACCGAAGC TGCCCTACGA CTATGCCGCC CTGGAGCCTA TCATCTGCCG GGAGATCATG 
GAGCTGCATC ACCAGAAGCA CCACCAGACC TACGTCAACA ATCTAAATGC CGCCGAGGAG 
CAGCTGGAGG AGGCCAAGTC GAAGAGCGAC ACCACCAAGC TGATTCAGCT GGCTCCTGCC 
CTGCGTTTCA ATGGCGGTGG CCACATCAAC CACACCATCT TCTGGCAGAA CCTCTCGCCC 
AACAAGACCC AGCCCAGCGA TGATCTGAAG AAGGCCATCG AGTCGCAGTG GAAGAGCCTC 
GAGGAGTTCA AAAAGGAGCT GACCACGCTG ACCGTGGCGG TCCAGGGCTC CGGCTGGGGC 
TGGCTGGGCT TCAACAAGAA GTCGGGCAAA CTGCAACTGG CCGCCCTGCC CAACCAGGAT 
CCCCTGGAGG CCTCCACCGG CCTGATCCCG CTCTTCGGCA TCGATGTCTG GGAGCACGCC 
TACTATCTGC AGTACAAGAA CGTGCGTCCC TCCTACGTGG AGGCCATCTG GGACATCGCC 
AACTGGGATG ACATCTCGTG CCGCTTCCAG GAGGCCAAGA AGCTCGGTTG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_476925.1
CDS	127..780
Translation	MFVARKISQTASLAVRGKHTLPKLPYDYAALEPIICREIMELHHQKHHQTYVNNLNAAEEQLEEAKSKSDTTKLIQLAPALRFNGGGHINHTIFWQNLSPNKTQPSDDLKKAIESQWKSLEEFKKELTTLTVAVQGSGWGWLGFNKKSGKLQLAALPNQDPLEASTGLIPLFGIDVWEHAYYLQYKNVRPSYVEAIWDIANWDDISCRFQEAKKLGC

Target ORF information:

RefSeq Version	NM_057577.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster superoxide dismutase 2 (Mn), transcript variant A (Sod2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_057577.4

ORF Insert Sequence:

ATGTTCGTGG CCCGTAAAAT TTCGCAAACT GCAAGCCTGG CGGTGCGTGG CAAGCACACC 
CTACCGAAGC TGCCCTACGA CTATGCCGCC CTGGAGCCTA TCATCTGCCG GGAGATCATG 
GAGCTGCATC ACCAGAAGCA CCACCAGACC TACGTCAACA ATCTAAATGC CGCCGAGGAG 
CAGCTGGAGG AGGCCAAGTC GAAGAGCGAC ACCACCAAGC TGATTCAGCT GGCTCCTGCC 
CTGCGTTTCA ATGGCGGTGG CCACATCAAC CACACCATCT TCTGGCAGAA CCTCTCGCCC 
AACAAGACCC AGCCCAGCGA TGATCTGAAG AAGGCCATCG AGTCGCAGTG GAAGAGCCTC 
GAGGAGTTCA AAAAGGAGCT GACCACGCTG ACCGTGGCGG TCCAGGGCTC CGGCTGGGGC 
TGGCTGGGCT TCAACAAGAA GTCGGGCAAA CTGCAACTGG CCGCCCTGCC CAACCAGGAT 
CCCCTGGAGG CCTCCACCGG CCTGATCCCG CTCTTCGGCA TCGATGTCTG GGAGCACGCC 
TACTATCTGC AGTACAAGAA CGTGCGTCCC TCCTACGTGG AGGCCATCTG GGACATCGCC 
AACTGGGATG ACATCTCGTG CCGCTTCCAG GAGGCCAAGA AGCTCGGTTG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Sod2 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報