Ggamma1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ggamma1
Entrez Gene ID	35881
Full Name	G protein gamma 1
Synonyms	CG8261,D-G[[gamma]]1,Dmel\CG8261,GNG13,G[[gamma1]],G[[gamma]],Gbetagamma,Gg1,Ggamma,Ggamma-1,bro4,dg1alpha,ggamma1,l(2)k08017
General protein information	Preferred Names G protein gamma 1 Names CG8261 gene product from transcript CG8261-RC CG8261-PA CG8261-PB CG8261-PC G protein Gg1 G protein gamma1 G protein subunit gamma1 G-protein gamma subunit 1 Ggamma1-PA Ggamma1-PB Ggamma1-PC
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2R Map Location: 44F3-44F5

mRNA and Protein(s)

mRNA	Protein	Name
NM_078938.3	NP_523662.1	G protein gamma 1, isoform C
NM_165632.2	NP_724719.1	G protein gamma 1, isoform B
NM_165631.2	NP_724718.1	G protein gamma 1, isoform A

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	Ggamma1	NP_523662.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010589	XP_314554.2

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Galphaq, Ggamma1 and Plc21C are anti-obesity genes and Akh employs the Galphaq/Ggamma1/Plc21C module of iCa(2+) control to regulate lipid mobilization in adult Drosophila.
Title: G?q, G?1 and Plc21C control Drosophila body fat storage.

We show that production of this PGC attractant depends upon shf as well as a second hh pathway gene g gamma1.
Title: The hedgehog pathway gene shifted functions together with the hmgcr-dependent isoprenoid biosynthetic pathway to orchestrate germ cell migration.

findings show that Ggamma1 is a component of the Hedgehog signaling pathway & is required for the efficient release of the Hh ligand from hh expressing cells; also Ggamma1 is required for germ cell migration
Title: Ggamma1, a downstream target for the hmgcr-isoprenoid biosynthetic pathway, is required for releasing the Hedgehog ligand and directing germ cell migration.

Study shows that G-oalpha47A and Gbeta13F cooperate with Ggamma1 to maintain cardiac integrity in Drosophila.
Title: Heterotrimeric G proteins regulate a noncanonical function of septate junction proteins to maintain cardiac integrity in Drosophila.

findings reveal a cardial cell-autonomous requirement of Ggamma1 geranylgeranylation for heart formation and suggest the involvement of the mevalonate pathway in congenital heart disease
Title: The mevalonate pathway controls heart formation in Drosophila by isoprenylation of Ggamma1.

The following Ggamma1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ggamma1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OFa12816	NM_078938.3 Latest version!	Drosophila melanogaster G protein gamma 1 (Ggamma1), transcript variant C, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OFa12816	NM_165631.2 Latest version!	Drosophila melanogaster G protein gamma 1 (Ggamma1), transcript variant A, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OFa12816	NM_165632.2 Latest version!	Drosophila melanogaster G protein gamma 1 (Ggamma1), transcript variant B, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ggamma1 ( NM_078938.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_523662.1 Drosophila melanogaster G protein gamma 1 (Ggamma1), transcript variant C, mRNA.

Price & Availability↑

CloneID	OFa12816
Clone ID Related Accession (Same CDS sequence)	NM_078938.3 , NM_165632.2 , NM_165631.2
Accession Version	NM_078938.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 213bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	G protein gamma 1, isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jan 16, 2013 this sequence version replaced NM_078938.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGACGTAA TGTCATCATC CCTGCAGCAG CAGCGCGTCG TGGTGGAGCA GCTGCGTCGC 
GAGGCTGCCA TCGACCGCCA GACGATCTCG GAGTCATGCG CTAAGATGAT GAAGTACATC 
ACGGAGCACG AGCAGGAGGA CTACCTGCTC ACCGGGTTCA CCAGCCAGAA GGTGAATCCC 
TTCCGCGAGA AGTCGTCCTG CACCGTTCTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_523662.1
CDS	49..261
Translation	MDVMSSSLQQQRVVVEQLRREAAIDRQTISESCAKMMKYITEHEQEDYLLTGFTSQKVNPFREKSSCTVL

Target ORF information:

RefSeq Version	NM_078938.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster G protein gamma 1 (Ggamma1), transcript variant C, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_078938.3

ORF Insert Sequence:

ATGGACGTAA TGTCATCATC CCTGCAGCAG CAGCGCGTCG TGGTGGAGCA GCTGCGTCGC 
GAGGCTGCCA TCGACCGCCA GACGATCTCG GAGTCATGCG CTAAGATGAT GAAGTACATC 
ACGGAGCACG AGCAGGAGGA CTACCTGCTC ACCGGGTTCA CCAGCCAGAA GGTGAATCCC 
TTCCGCGAGA AGTCGTCCTG CACCGTTCTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ggamma1 ( NM_165632.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_724719.1 Drosophila melanogaster G protein gamma 1 (Ggamma1), transcript variant B, mRNA.

Price & Availability↑

CloneID	OFa12816
Clone ID Related Accession (Same CDS sequence)	NM_078938.3 , NM_165632.2 , NM_165631.2
Accession Version	NM_165632.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 213bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	G protein gamma 1, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jan 16, 2013 this sequence version replaced NM_165632.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGACGTAA TGTCATCATC CCTGCAGCAG CAGCGCGTCG TGGTGGAGCA GCTGCGTCGC 
GAGGCTGCCA TCGACCGCCA GACGATCTCG GAGTCATGCG CTAAGATGAT GAAGTACATC 
ACGGAGCACG AGCAGGAGGA CTACCTGCTC ACCGGGTTCA CCAGCCAGAA GGTGAATCCC 
TTCCGCGAGA AGTCGTCCTG CACCGTTCTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_724719.1
CDS	302..514
Translation	MDVMSSSLQQQRVVVEQLRREAAIDRQTISESCAKMMKYITEHEQEDYLLTGFTSQKVNPFREKSSCTVL

Target ORF information:

RefSeq Version	NM_165632.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster G protein gamma 1 (Ggamma1), transcript variant B, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_165632.2

ORF Insert Sequence:

ATGGACGTAA TGTCATCATC CCTGCAGCAG CAGCGCGTCG TGGTGGAGCA GCTGCGTCGC 
GAGGCTGCCA TCGACCGCCA GACGATCTCG GAGTCATGCG CTAAGATGAT GAAGTACATC 
ACGGAGCACG AGCAGGAGGA CTACCTGCTC ACCGGGTTCA CCAGCCAGAA GGTGAATCCC 
TTCCGCGAGA AGTCGTCCTG CACCGTTCTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ggamma1 ( NM_165631.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_724718.1 Drosophila melanogaster G protein gamma 1 (Ggamma1), transcript variant A, mRNA.

Price & Availability↑

CloneID	OFa12816
Clone ID Related Accession (Same CDS sequence)	NM_078938.3 , NM_165632.2 , NM_165631.2
Accession Version	NM_165631.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 213bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	G protein gamma 1, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jan 16, 2013 this sequence version replaced NM_165631.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGACGTAA TGTCATCATC CCTGCAGCAG CAGCGCGTCG TGGTGGAGCA GCTGCGTCGC 
GAGGCTGCCA TCGACCGCCA GACGATCTCG GAGTCATGCG CTAAGATGAT GAAGTACATC 
ACGGAGCACG AGCAGGAGGA CTACCTGCTC ACCGGGTTCA CCAGCCAGAA GGTGAATCCC 
TTCCGCGAGA AGTCGTCCTG CACCGTTCTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_724718.1
CDS	111..323
Translation	MDVMSSSLQQQRVVVEQLRREAAIDRQTISESCAKMMKYITEHEQEDYLLTGFTSQKVNPFREKSSCTVL

Target ORF information:

RefSeq Version	NM_165631.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster G protein gamma 1 (Ggamma1), transcript variant A, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_165631.2

ORF Insert Sequence:

ATGGACGTAA TGTCATCATC CCTGCAGCAG CAGCGCGTCG TGGTGGAGCA GCTGCGTCGC 
GAGGCTGCCA TCGACCGCCA GACGATCTCG GAGTCATGCG CTAAGATGAT GAAGTACATC 
ACGGAGCACG AGCAGGAGGA CTACCTGCTC ACCGGGTTCA CCAGCCAGAA GGTGAATCCC 
TTCCGCGAGA AGTCGTCCTG CACCGTTCTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Ggamma1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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